Detailed information for compound 723869

Basic information

Technical information
  • TDR Targets ID: 723869
  • Name: 3-(3-chloro-4-fluorophenyl)-1-(thiophen-2-ylm ethyl)thiourea
  • MW: 300.803 | Formula: C12H10ClFN2S2
  • H donors: 2 H acceptors: 0 LogP: 3.47 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C(Nc1ccc(c(c1)Cl)F)NCc1cccs1
  • InChi: 1S/C12H10ClFN2S2/c13-10-6-8(3-4-11(10)14)16-12(17)15-7-9-2-1-5-18-9/h1-6H,7H2,(H2,15,16,17)
  • InChiKey: CWWDHFSVFKXMRP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-(3-chloro-4-fluoro-phenyl)-1-(2-thienylmethyl)thiourea
  • 3-(3-chloro-4-fluorophenyl)-1-(2-thienylmethyl)thiourea
  • 3-(3-chloro-4-fluoro-phenyl)-1-(thiophen-2-ylmethyl)thiourea
  • ZINC00089112
  • STK164884
  • SR-01000632799-1

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0158
Echinococcus granulosus Squalene phytoene synthase 0.0022 0.0022 0.0022
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0017 0.0039
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0012 0.0002 0.0002
Echinococcus granulosus snurportin 1 0.0173 0.0333 0.0333
Echinococcus multilocularis carboxylesterase 5A 0.0091 0.0165 0.0165
Schistosoma mansoni tar DNA-binding protein 0.0167 0.0321 0.0739
Loa Loa (eye worm) hypothetical protein 0.0034 0.0047 0.0229
Echinococcus granulosus pyruvate kinase 0.0023 0.0026 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0003 0.002
Treponema pallidum 76K protein 0.0091 0.0164 0.0177
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0022 0.0022 0.0022
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0031 0.0041 0.2115
Echinococcus granulosus pyruvate kinase 0.0023 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Echinococcus granulosus pyruvate kinase 0.0012 0.0002 0.0002
Toxoplasma gondii LsmAD domain-containing protein 0.0032 0.0044 0.2241
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0028 0.0034 0.0168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0017 0.008
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0031 0.0041 0.0279
Mycobacterium ulcerans hypothetical protein 0.0019 0.0017 0.0115
Schistosoma mansoni glutamate receptor NMDA 0.0028 0.0034 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0078
Onchocerca volvulus 0.0028 0.0034 0.1628
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0015 0.0007 0.0007
Echinococcus granulosus inositol monophosphatase 1 0.0066 0.0114 0.0114
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0012 0.0002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0132
Plasmodium vivax pyruvate kinase, putative 0.0023 0.0026 0.1253
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Brugia malayi MH2 domain containing protein 0.0122 0.0228 0.1136
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0168
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.213 0.435 1
Echinococcus granulosus GPCR family 3 C terminal 0.0048 0.0076 0.0076
Brugia malayi Bromodomain containing protein 0.0021 0.0021 0.0098
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0015 0.0009 0.0063
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0019 0.0017 0.0038
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0015 0.0009 0.0021
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0003 0.002
Mycobacterium ulcerans phytoene synthase, CrtB 0.0022 0.0022 0.0152
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0091 0.0164 0.8469
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0017 0.0038
Echinococcus granulosus neuropeptide receptor A26 0.0926 0.1879 0.1879
Toxoplasma gondii pyruvate kinase PyK1 0.0023 0.0026 0.1287
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0012 0.0002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0041
Giardia lamblia PHD finger protein 15 0.002 0.0018 0.085
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0039 0.0058 0.1602
Onchocerca volvulus 0.0091 0.0164 0.8056
Trichomonas vaginalis inositol monophosphatase, putative 0.0066 0.0114 0.0779
Echinococcus multilocularis Mastin 0.0019 0.0017 0.0017
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0066 0.0114 0.5901
Leishmania major phosphoglycerate kinase C, glycosomal 0.0105 0.0193 0.5417
Leishmania major 4-coumarate:coa ligase-like protein 0.0033 0.0044 0.1227
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0017 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0002 0.0021
Echinococcus multilocularis acetylcholinesterase 0.0091 0.0165 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0017 0.0078
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0047 0.0323
Trypanosoma brucei importin beta-1 subunit, putative 0.0016 0.0011 0.0276
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0015 0.0009 0.0021
Leishmania major hypothetical protein, conserved 0.0022 0.0022 0.0599
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Plasmodium falciparum phosphoglycerate kinase 0.0105 0.0193 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0017 0.0017
Echinococcus multilocularis GPCR, family 3, C terminal 0.0048 0.0076 0.0076
Echinococcus granulosus BC026374 protein S09 family 0.0015 0.0009 0.0009
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0117 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0015 0.0007 0.0007
Schistosoma mansoni rotamase 0.0012 0.0001 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0044 0.0215
Echinococcus multilocularis survival motor neuron protein 1 0.0159 0.0304 0.0304
Schistosoma mansoni hypothetical protein 0.0014 0.0005 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0044 0.0215
Echinococcus multilocularis neuropeptide s receptor 0.0926 0.1879 0.1879
Entamoeba histolytica hypothetical protein 0.0043 0.0065 0.3333
Plasmodium vivax pyruvate kinase 2, putative 0.0012 0.0002 0.0026
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0117 0.0217 0.0217
Echinococcus multilocularis tumor protein p63 0.0465 0.0932 0.0932
Brugia malayi hypothetical protein 0.0159 0.0304 0.1515
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0039 0.0058 0.2957
Echinococcus multilocularis muscleblind protein 1 0.0098 0.018 0.018
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Brugia malayi hypothetical protein 0.0032 0.0044 0.0213
Entamoeba histolytica acyl-coA synthetase, putative 0.0033 0.0044 0.2265
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0359 0.0826
Loa Loa (eye worm) glutamate receptor 0.0116 0.0216 0.1078
Brugia malayi hypothetical protein 0.0015 0.0009 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0017 0.008
Echinococcus granulosus L aminoadipate semialdehyde 0.011 0.0203 0.0203
Entamoeba histolytica elongation factor-2 kinase, putative 0.0091 0.0164 0.8475
Brugia malayi Receptor family ligand binding region containing protein 0.0028 0.0034 0.0166
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Echinococcus multilocularis muscleblind protein 0.0098 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0055 0.0091 0.0449
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0013 0.0004 0.003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0039 0.0058 0.1602
Loa Loa (eye worm) hypothetical protein 0.0048 0.0076 0.0375
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Echinococcus granulosus dnaJ subfamily B 0.0288 0.0568 0.0568
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0015 0.0009 0.0476
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0184 0.0355 1
Schistosoma mansoni gliotactin 0.0015 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0041
Leishmania major phosphopantetheinyl transferase-like protein 0.0031 0.0041 0.1125
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0017 0.0076
Loa Loa (eye worm) carboxylesterase 0.0015 0.0009 0.0041
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Echinococcus multilocularis chromobox protein 1 0.0024 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0168
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0087 0.0156 0.4384
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0123
Loa Loa (eye worm) hypothetical protein 0.0033 0.0045 0.0222
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Schistosoma mansoni cellular tumor antigen P53 0.0068 0.0117 0.0269
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0019 0.0017 0.0451
Brugia malayi Importin beta-1 subunit 0.0016 0.0011 0.0046
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0012 0.0002 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0012 0.0002 0.0005
Echinococcus granulosus glutamate receptor 2 0.0028 0.0034 0.0034
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0024 0.0027 0.1425
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.011 0.0203 0.0466
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0076 0.0133 0.0661
Schistosoma mansoni hypothetical protein 0.0091 0.0164 0.0376
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0041 0.1125
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0017 0.0017
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0015 0.0009 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0003 0.002
Schistosoma mansoni hypothetical protein 0.0015 0.0007 0.0017
Echinococcus multilocularis pyruvate kinase 0.0023 0.0026 0.0026
Brugia malayi Pyruvate kinase, M2 isozyme 0.0023 0.0026 0.0121
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0079 0.0139 0.0321
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0051
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Brugia malayi glutaminase DH11.1 0.0723 0.1461 0.732
Giardia lamblia Pyruvate kinase 0.0012 0.0002 0.0026
Echinococcus granulosus tar DNA binding protein 0.0167 0.0321 0.0321
Plasmodium falciparum importin beta, putative 0.0016 0.0011 0.0473
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0336 0.0667 0.1534
Brugia malayi steroid hormone receptor 0.0019 0.0017 0.0078
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0063 0.0063
Echinococcus granulosus cpg binding protein 0.0041 0.0061 0.0061
Plasmodium falciparum thrombospondin-related anonymous protein 0.0091 0.0164 0.8469
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0017 0.0078
Echinococcus multilocularis pyruvate kinase 0.0019 0.0015 0.0015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0022 0.0022 0.0022
Schistosoma mansoni ap endonuclease 0.0012 0.0002 0.0004
Schistosoma mansoni tyrosine kinase 0.0028 0.0034 0.0079
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.0026 0.0697
Entamoeba histolytica hypothetical protein 0.0031 0.0041 0.2077
Mycobacterium ulcerans pyruvate kinase 0.0023 0.0026 0.0175
Trypanosoma cruzi PAB1-binding protein , putative 0.0032 0.0044 0.1214
Brugia malayi RNA binding protein 0.0167 0.0321 0.1604
Trypanosoma brucei phosphoglycerate kinase 0.0105 0.0193 0.5417
Trypanosoma brucei phosphoglycerate kinase 0.0039 0.0057 0.1569
Schistosoma mansoni jumonji/arid domain-containing protein 0.0027 0.0033 0.0077
Echinococcus multilocularis tar DNA binding protein 0.0167 0.0321 0.0321
Echinococcus granulosus tumor protein p63 0.0465 0.0932 0.0932
Entamoeba histolytica phosphoglycerate kinase, putative 0.0105 0.0193 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0063 0.0063
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0017 0.0017
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Echinococcus granulosus metabotropic glutamate receptor 5 0.0364 0.0724 0.0724
Plasmodium falciparum flap endonuclease 1 0.0019 0.0017 0.0797
Trypanosoma brucei PAB1-binding protein , putative 0.0032 0.0044 0.1214
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0033 0.0045 0.0045
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0022 0.0022 0.0022
Echinococcus granulosus nmda type glutamate receptor 0.0028 0.0034 0.0034
Schistosoma mansoni cpg binding protein 0.0037 0.0054 0.0124
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Leishmania major importin beta-1 subunit, putative 0.0013 0.0004 0.0099
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.005
Brugia malayi von Willebrand Factor 0.0091 0.0164 0.0813
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0017 0.0078
Schistosoma mansoni serine-rich repeat protein 0.1147 0.2332 0.5361
Echinococcus multilocularis pyruvate kinase 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0068 0.0117 0.5741
Schistosoma mansoni methyl-cpg binding protein mbd 0.0011 0.0001 0.0001
Echinococcus granulosus voltage dependent calcium channel subunit 0.2221 0.4536 0.4536
Schistosoma mansoni jumonji/arid domain-containing protein 0.0027 0.0033 0.0077
Plasmodium vivax acyl-CoA synthetase, putative 0.0024 0.0027 0.1349
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0017 0.0017
Echinococcus granulosus metabotropic glutamate receptor 2 0.0248 0.0486 0.0486
Echinococcus multilocularis nmda type glutamate receptor 0.0028 0.0034 0.0034
Onchocerca volvulus 0.0015 0.0009 0.0367
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0026 0.0123
Trichomonas vaginalis rotamase, putative 0.0011 0.0001 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0017 0.008
Echinococcus granulosus receptor type guanylyl cyclase 0.0028 0.0034 0.0034
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0173 0.0333 0.1662
Loa Loa (eye worm) hypothetical protein 0.0098 0.018 0.0895
Leishmania major 4-coumarate:coa ligase-like protein 0.0033 0.0044 0.1227
Onchocerca volvulus 0.0032 0.0044 0.21
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0017 0.0078
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0168
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0041
Brugia malayi hypothetical protein 0.0019 0.0017 0.0076
Entamoeba histolytica hypothetical protein 0.0091 0.0164 0.8475
Trichomonas vaginalis importin beta-1, putative 0.0013 0.0004 0.003
Echinococcus multilocularis L aminoadipate semialdehyde 0.011 0.0203 0.0203
Echinococcus granulosus phosphoglycerate kinase 1 0.0105 0.0193 0.0193
Trypanosoma brucei phosphoglycerate kinase 0.0105 0.0193 0.5417
Echinococcus multilocularis dnaJ subfamily B 0.0288 0.0568 0.0568
Echinococcus multilocularis glutamate receptor 2 0.0028 0.0034 0.0034
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0033 0.0045 0.0045
Echinococcus multilocularis transmembrane protease serine 3 0.0019 0.0017 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0359 0.0359
Trypanosoma cruzi squalene synthase, putative 0.007 0.0121 0.3384
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0017 0.0017
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.0026 0.0175
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0025 0.1283
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0031 0.0041 0.2077
Toxoplasma gondii hypothetical protein 0.003 0.0038 0.1952
Brugia malayi Flap endonuclease-1 0.0019 0.0017 0.0077
Loa Loa (eye worm) TAR-binding protein 0.0167 0.0321 0.1605
Echinococcus multilocularis SAM and MBT domain containing protein 0.0029 0.0037 0.0037
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0003 0.002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0017 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0017 0.0078
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0003 0.002
Brugia malayi Latrophilin receptor protein 2 0.0022 0.0022 0.0103
Loa Loa (eye worm) latrophilin receptor protein 2 0.0022 0.0022 0.0105
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Schistosoma mansoni hypothetical protein 0.002 0.0018 0.0041
Plasmodium vivax hypothetical protein, conserved 0.002 0.0018 0.085
Echinococcus granulosus para nitrobenzyl esterase 0.0015 0.0009 0.0009
Echinococcus multilocularis zinc finger protein 0.0015 0.0008 0.0008
Plasmodium falciparum pyruvate kinase 0.0023 0.0026 0.1253
Onchocerca volvulus Alhambra homolog 0.002 0.0018 0.0803
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0051
Loa Loa (eye worm) hypothetical protein 0.0069 0.0118 0.0587
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0051
Toxoplasma gondii pyruvate kinase PyKII 0.0012 0.0002 0.0065
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0039 0.0057 0.1569
Echinococcus granulosus methyl CpG binding domain protein 2 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0085 0.0152 0.7489
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0078
Echinococcus granulosus SAM and MBT domain containing protein 0.0029 0.0037 0.0037
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0012 0.0002 0.0002
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0031 0.0041 0.0279
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0065 0.0065
Schistosoma mansoni cpg binding protein 0.0041 0.0061 0.014
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0031 0.0041 0.0906
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.001 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.0032 0.0044 0.1214
Schistosoma mansoni neuroligin 3 (S09 family) 0.0015 0.0009 0.0021
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0017 0.008
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0044 0.0215
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0361
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0132
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0012 0.0001 0.0002
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0105 0.0193 0.5417
Loa Loa (eye worm) glutaminase 2 0.0723 0.1461 0.732
Schistosoma mansoni jumonji domain containing protein 0.0051 0.0083 0.019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.0359 0.1795
Echinococcus multilocularis neuropeptide receptor A26 0.0926 0.1879 0.1879
Echinococcus granulosus lysine specific demethylase 5A 0.0027 0.0033 0.0033
Leishmania major pyruvate kinase 0.0023 0.0026 0.0697
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0015 0.0009 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0015 0.0008 0.0053
Brugia malayi PHD-finger family protein 0.002 0.0018 0.0082
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0003 0.002
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0105 0.0193 0.132
Brugia malayi Muscleblind-like protein 0.0098 0.018 0.0893
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0217
Plasmodium falciparum ataxin-2 like protein, putative 0.0032 0.0044 0.221
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0217
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0039 0.0057 0.1569
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0017 0.0758
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0015 0.0008 0.0294
Schistosoma mansoni hypothetical protein 0.0043 0.0065 0.0149
Brugia malayi Bromodomain containing protein 0.0052 0.0083 0.041
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0017 0.0078
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0215
Leishmania major mitochondrial DNA polymerase beta 0.0184 0.0355 1
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.4522 0.9259 1
Brugia malayi Trypsin-like protease protein 5 0.0019 0.0017 0.0076
Loa Loa (eye worm) hypothetical protein 0.0159 0.0304 0.1517
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0023 0.0026 0.1329
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0028 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0168
Echinococcus granulosus transmembrane protease serine 3 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Toxoplasma gondii exonuclease III APE 0.0012 0.0002 0.0039
Loa Loa (eye worm) PHD-finger family protein 0.0014 0.0005 0.0021
Onchocerca volvulus 0.0091 0.0164 0.8056
Brugia malayi Calcitonin receptor-like protein seb-1 0.0069 0.0118 0.0585
Plasmodium vivax ataxin-2 like protein, putative 0.0032 0.0044 0.221
Echinococcus granulosus neuropeptide s receptor 0.0926 0.1879 0.1879
Loa Loa (eye worm) inositol-1 0.0066 0.0114 0.0565
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0168
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0039 0.0058 0.0284
Echinococcus multilocularis GPCR, family 2 0.0022 0.0022 0.0022
Loa Loa (eye worm) flap endonuclease-1 0.0019 0.0017 0.0079
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0026 0.0031 0.0837
Echinococcus granulosus glycoprotein Antigen 5 0.0019 0.0017 0.0017
Mycobacterium ulcerans phosphoglycerate kinase 0.0105 0.0193 0.132
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1046 0.2126 0.2126
Trichomonas vaginalis glutaminase, putative 0.0723 0.1461 1
Onchocerca volvulus 0.011 0.0203 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0228 0.1138
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Mycobacterium ulcerans hypothetical protein 0.0097 0.0176 0.1208
Schistosoma mansoni coup transcription factor 0.0019 0.0017 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Schistosoma mansoni inositol monophosphatase 0.0066 0.0114 0.0262
Brugia malayi Phosphoglycerate kinase 0.0039 0.0057 0.0276
Brugia malayi Receptor family ligand binding region containing protein 0.0076 0.0133 0.0659
Echinococcus multilocularis geminin 0.0191 0.0369 0.0369
Schistosoma mansoni hypothetical protein 0.0091 0.0164 0.0376
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0039 0.0058 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0025 0.1283
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0012 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0105 0.0193 0.0962
Schistosoma mansoni hypothetical protein 0.0191 0.0369 0.0848
Brugia malayi hypothetical protein 0.0091 0.0164 0.0813
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0031 0.0041 0.0044
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0033 0.0044 0.2302
Onchocerca volvulus 0.0091 0.0164 0.8056
Echinococcus multilocularis inositol monophosphatase 1 0.0066 0.0114 0.0114
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0032 0.0042 0.1165
Brugia malayi Heterochromatin protein 1 0.0024 0.0028 0.0131
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0105 0.0193 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0106
Echinococcus granulosus carboxylesterase 5A 0.0091 0.0165 0.0165
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0359 0.0359
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0001 0.001
Echinococcus granulosus survival motor neuron protein 1 0.0159 0.0304 0.0304
Loa Loa (eye worm) CXXC zinc finger family protein 0.0037 0.0054 0.0265
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0091 0.0164 0.0164
Schistosoma mansoni tar DNA-binding protein 0.0167 0.0321 0.0739
Brugia malayi chromobox protein homolog 3 0.0014 0.0006 0.002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0013 0.0004 0.0099
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0091 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0076 0.0133 0.0661
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0026 0.0031 0.0837
Brugia malayi exodeoxyribonuclease III family protein 0.0012 0.0002 0.0001
Entamoeba histolytica hypothetical protein, conserved 0.0091 0.0164 0.8475
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0017 0.0038
Trypanosoma brucei squalene synthase, putative 0.007 0.0121 0.3384
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0065 0.0065
Mycobacterium tuberculosis Carboxylesterase LipT 0.0015 0.0009 0.0476
Schistosoma mansoni inositol monophosphatase 0.0066 0.0114 0.0262
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0026 0.1187
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.1074 0.2182 0.5015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0003 0.002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0069 0.0118 0.0585
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0014 0.0006 0.0187
Brugia malayi latrophilin 2 splice variant baaae 0.0047 0.0074 0.0362
Echinococcus multilocularis peregrin 0.0021 0.0021 0.0021
Brugia malayi Carboxylesterase family protein 0.0015 0.0009 0.0039
Brugia malayi PHD-finger family protein 0.0019 0.0016 0.007
Brugia malayi nuclear receptor NHR-88 0.0019 0.0017 0.0078
Loa Loa (eye worm) glutamate receptor 0.0296 0.0584 0.2924
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0034 0.0047 0.0108
Trichomonas vaginalis ran, putative 0.0012 0.0002 0.0013
Leishmania major pyruvate kinase 0.0023 0.0026 0.0697
Echinococcus multilocularis BC026374 protein (S09 family) 0.0015 0.0009 0.0009
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0029 0.0037 0.0085
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0017 0.0038
Echinococcus multilocularis voltage dependent calcium channel subunit 0.4883 1 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0013 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0132
Brugia malayi metabotropic glutamate receptor type 2 0.0144 0.0273 0.1363
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Echinococcus multilocularis receptor type guanylyl cyclase 0.0028 0.0034 0.0034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0017 0.0017
Schistosoma mansoni survival motor neuron protein 0.0032 0.0044 0.0101
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0359 0.0826
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0012 0.0002 0.0002
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0018 0.0886
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0012 0.0002 0.0005
Schistosoma mansoni cpg binding protein 0.0041 0.0061 0.014
Treponema pallidum phosphoglycerate kinase 0.0105 0.0193 0.0208
Loa Loa (eye worm) hypothetical protein 0.0055 0.0091 0.0449
Loa Loa (eye worm) trypsin family protein 0.0019 0.0017 0.0078
Mycobacterium leprae Probable pyruvate kinase PykA 0.0023 0.0026 0.1329
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0364 0.0724 0.0724
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0031 0.0041 0.2077
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0091 0.0164 0.8469
Mycobacterium leprae conserved hypothetical protein 0.0031 0.0041 0.2115
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.0114 0.3186
Onchocerca volvulus 0.0015 0.0009 0.0367
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0012 0.0002 0.0028
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0047 0.0047
Schistosoma mansoni sex comb on midleg homolog 0.0029 0.0037 0.0085
Trichomonas vaginalis rotamase, putative 0.0012 0.0001 0.001
Echinococcus granulosus histone lysine methyltransferase setb 0.0012 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0017 0.0078
Onchocerca volvulus 0.0015 0.0009 0.0367
Schistosoma mansoni sex comb on midleg homolog 0.0029 0.0037 0.0085
Loa Loa (eye worm) hypothetical protein 0.0029 0.0037 0.0181
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0034 0.0047 0.2446
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0017 0.008
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0032 0.0042 0.0208
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0017 0.0017
Echinococcus granulosus importin subunit beta 1 0.0016 0.0011 0.0011
Trypanosoma cruzi extracellular receptor, putative 0.0028 0.0034 0.0947
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0017 0.0078
Echinococcus multilocularis phosphoglycerate kinase 1 0.0105 0.0193 0.0193
Onchocerca volvulus 0.0091 0.0164 0.8056
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0105 0.0193 1
Schistosoma mansoni ap endonuclease 0.0012 0.0002 0.0004
Schistosoma mansoni pyruvate kinase 0.0012 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Giardia lamblia Flap structure-specific endonuclease 0.0019 0.0017 0.0797
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0017 0.008
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0028 0.0034 0.0034
Echinococcus multilocularis neuroligin 0.0015 0.0009 0.0009
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0033 0.0045 0.022
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0028 0.0034 0.1628
Onchocerca volvulus 0.0019 0.0017 0.0744
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0018 0.0886
Brugia malayi Carboxylesterase family protein 0.0091 0.0165 0.0821
Echinococcus granulosus glutamate receptor 2 0.0028 0.0034 0.0034
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0039 0.0058 0.1602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0091 0.0164 0.0813
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0019 0.0017 0.0076
Schistosoma mansoni ran 0.0012 0.0002 0.0004
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0012 0.0002 0.0013
Brugia malayi Metabotropic glutamate receptor precursor. 0.0296 0.0584 0.2922
Schistosoma mansoni hypothetical protein 0.0019 0.0017 0.0038
Schistosoma mansoni hypothetical protein 0.0288 0.0568 0.1307
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0168
Echinococcus granulosus fetal alzheimer antigen falz 0.0017 0.0012 0.0012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0027 0.0188
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0015 0.0009 0.0476
Loa Loa (eye worm) acetylcholinesterase 1 0.0091 0.0165 0.0823
Echinococcus granulosus acetylcholinesterase 0.0091 0.0165 0.0165
Echinococcus granulosus neuroligin 0.0015 0.0009 0.0009
Loa Loa (eye worm) CUTiclin-Like family member 0.0091 0.0164 0.0815
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0033 0.0044 0.2302
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Schistosoma mansoni hypothetical protein 0.0019 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0098 0.018 0.0895
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0028 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0047 0.0074 0.0364
Loa Loa (eye worm) MBCTL1 0.0033 0.0045 0.0222
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Loa Loa (eye worm) hypothetical protein 0.0033 0.0044 0.0217
Brugia malayi hypothetical protein 0.0082 0.0146 0.0727
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0028 0.0034 0.0034
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0066 0.0114 0.5882
Brugia malayi CXXC zinc finger family protein 0.0037 0.0054 0.0263
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0041
Trypanosoma cruzi pyruvate kinase 2, putative 0.0023 0.0026 0.0697
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0011 0.0001 0.0001
Echinococcus granulosus pyruvate kinase 0.0012 0.0002 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0032 0.0044 0.221
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0017 0.0017
Entamoeba histolytica Flap nuclease, putative 0.0019 0.0017 0.0833
Echinococcus granulosus expressed protein 0.0012 0.0001 0.0001
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0039 0.0057 0.1569
Schistosoma mansoni hypothetical protein 0.0048 0.0076 0.0175
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0034 0.0168
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0087 0.0156 0.4384
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.0114 0.3186
Echinococcus granulosus histone acetyltransferase MYST2 0.0033 0.0045 0.0045
Echinococcus multilocularis tyrosine kinase 0.0028 0.0034 0.0034
Echinococcus multilocularis para nitrobenzyl esterase 0.0015 0.0009 0.0009
Echinococcus granulosus collagen alpha 1VII chain 0.0091 0.0164 0.0164
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0024 0.0026 0.0026
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0028 0.0034 0.0034
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0033 0.0044 0.2302
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0059 0.01 0.516
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0017 0.0038
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0028 0.0034 0.0034
Echinococcus granulosus atrial natriuretic peptide receptor 0.0028 0.0034 0.0034
Echinococcus multilocularis lysine specific demethylase 5A 0.0024 0.0026 0.0026
Echinococcus granulosus flap endonuclease 1 0.0019 0.0017 0.0017
Schistosoma mansoni metabotropic glutamate receptor 0.0144 0.0273 0.0628
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0017 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0017 0.0078
Schistosoma mansoni BC026374 protein (S09 family) 0.0015 0.0009 0.0021
Entamoeba histolytica hypothetical protein 0.0043 0.0065 0.3333
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0132
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0248 0.0486 0.0486
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0184 0.0355 1
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0091 0.0164 0.112
Loa Loa (eye worm) mbt repeat family protein 0.0029 0.0037 0.0181
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0012 0.0002 0.0028
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0091 0.0164 0.8475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0017 0.008
Echinococcus granulosus geminin 0.0191 0.0369 0.0369
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0105 0.0193 0.132
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.0114 0.3186
Echinococcus granulosus muscleblind protein 0.0098 0.018 0.018
Toxoplasma gondii HEAT repeat-containing protein 0.0016 0.0011 0.051
Echinococcus multilocularis polycomb protein SCMH1 0.0029 0.0037 0.0037
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0028 0.0034 0.0166
Loa Loa (eye worm) hypothetical protein 0.011 0.0203 0.1011
Echinococcus multilocularis chromobox protein 1 0.0024 0.0028 0.0028
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0039 0.0057 0.1569
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0066 0.0114 0.0779
Trypanosoma brucei phosphoglycerate kinase, putative 0.0039 0.0057 0.1569
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0012 0.0002 0.0002
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0039 0.0058 0.0133
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0059 0.01 0.516
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0017 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0028 0.0189
Leishmania major 4-coumarate:coa ligase-like protein 0.0033 0.0044 0.1227
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0184 0.0355 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0047 0.0047
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0026 0.0031 0.0837
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0359 0.0359
Echinococcus multilocularis Squalene phytoene synthase 0.0022 0.0022 0.0022
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0091 0.0164 0.8469
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0002 0.0011
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Schistosoma mansoni hypothetical protein 0.0047 0.0074 0.0169
Echinococcus multilocularis snurportin 1 0.0173 0.0333 0.0333
Trichomonas vaginalis flap endonuclease-1, putative 0.0019 0.0017 0.0116
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0026 0.0031 0.0837
Onchocerca volvulus 0.0029 0.0037 0.1759
Trypanosoma cruzi squalene synthase, putative 0.007 0.0121 0.3384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Brugia malayi RNA recognition motif domain containing protein 0.0167 0.0321 0.1604
Leishmania major hypothetical protein, conserved 0.0032 0.0044 0.1214
Brugia malayi Trypsin family protein 0.0019 0.0017 0.0076
Schistosoma mansoni bromodomain containing protein 0.0044 0.0067 0.0155
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0048 0.0076 0.3691
Loa Loa (eye worm) pyruvate kinase-PB 0.0016 0.0011 0.005
Plasmodium vivax thrombospondin-related anonymous protein 0.0091 0.0164 0.8469
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0017 0.0078
Echinococcus multilocularis expressed protein 0.0012 0.0001 0.0001
Echinococcus granulosus GTP binding nuclear protein Ran 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0034 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0017 0.0078
Trypanosoma brucei importin beta-1 subunit, putative 0.0016 0.0011 0.0276
Schistosoma mansoni methyl-cpg binding protein mbd 0.0011 0.0001 0.0001
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0228 0.1138
Brugia malayi Trypsin family protein 0.0055 0.0091 0.0447
Treponema pallidum hypothetical protein 0.0091 0.0164 0.0177
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0026 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0038
Schistosoma mansoni importin beta-1 0.0016 0.0011 0.0025
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.011 0.011
Brugia malayi hypothetical protein 0.0043 0.0065 0.0318
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0003 0.002
Loa Loa (eye worm) hypothetical protein 0.0364 0.0724 0.3627
Schistosoma mansoni zinc finger protein 0.0015 0.0008 0.0019
Schistosoma mansoni acetylcholinesterase 0.0015 0.0009 0.0021
Echinococcus granulosus jumonji domain containing protein 0.0027 0.0034 0.0034
Loa Loa (eye worm) RNA binding protein 0.0167 0.0321 0.1605
Toxoplasma gondii microneme protein MIC2 0.0091 0.0164 0.8475
Brugia malayi jmjC domain containing protein 0.0027 0.0033 0.016
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0019 0.0017 0.0833
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0055 0.0091 0.0208
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0017 0.0017
Schistosoma mansoni glutaminase 0.0723 0.1461 0.3359
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0017 0.0078
Schistosoma mansoni ran 0.0012 0.0002 0.0004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0022 0.0022 0.0022
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0017 0.0017
Chlamydia trachomatis phosphoglycerate kinase 0.0105 0.0193 1
Onchocerca volvulus Huntingtin homolog 0.0082 0.0146 0.7202
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0019 0.0017 0.0451
Schistosoma mansoni chromobox protein 0.0024 0.0028 0.0063
Onchocerca volvulus Huntingtin homolog 0.0082 0.0146 0.7202
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0012 0.0002 0.0011
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0091 0.0164 0.8469
Brugia malayi Trypsin family protein 0.0019 0.0017 0.0076
Treponema pallidum exodeoxyribonuclease (exoA) 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0015 0.0009 0.0367
Onchocerca volvulus 0.0091 0.0164 0.8056
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0091 0.0164 0.0815
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0048 0.0076 0.0373
Mycobacterium ulcerans acyl-CoA synthetase 0.0033 0.0044 0.0304
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0017 0.0017
Echinococcus granulosus polycomb protein SCMH1 0.0029 0.0037 0.0037
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0034 0.0047 0.0229
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0012 0.0002 0.0087
Mycobacterium ulcerans acyl-CoA synthetase 0.0033 0.0044 0.0304
Schistosoma mansoni hypothetical protein 0.0191 0.0369 0.0848
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0012 0.0002 0.0021
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0017 0.0012 0.0028
Onchocerca volvulus 0.0019 0.0017 0.0744
Plasmodium falciparum phd finger protein, putative 0.002 0.0018 0.085
Onchocerca volvulus 0.0037 0.0054 0.2591
Echinococcus multilocularis glutamate receptor 2 0.0028 0.0034 0.0034
Echinococcus granulosus GPCR family 2 0.0022 0.0022 0.0022
Leishmania major extracellular receptor, putative 0.0028 0.0034 0.0947
Echinococcus granulosus pyruvate kinase 0.0012 0.0002 0.0002
Echinococcus multilocularis importin subunit beta 1 0.0016 0.0011 0.0011
Brugia malayi Cache domain containing protein 0.0983 0.1995 1
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0017 0.0017
Mycobacterium ulcerans hypothetical protein 0.0033 0.0044 0.0304
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0033 0.0044 0.0304
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0091 0.0164 0.8469
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0012 0.0002 0.0021
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0017 0.0039
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0031 0.0041 0.2045
Mycobacterium ulcerans acyl-CoA synthetase 0.0033 0.0044 0.0304
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0068 0.0117 0.0582
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0039 0.0058 0.0058
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0034 0.0168
Brugia malayi Pyruvate kinase, muscle isozyme 0.0023 0.0026 0.0121
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0017 0.0039
Echinococcus multilocularis jumonji domain containing protein 0.0027 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0043 0.0065 0.3333
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0164 0.8469
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0017 0.0078
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0041
Schistosoma mansoni pyruvate kinase 0.0023 0.0026 0.0059
Brugia malayi ecdysteroid receptor 0.0019 0.0017 0.0078
Brugia malayi Carboxylesterase family protein 0.0015 0.0009 0.0039
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0026 0.1187
Trichomonas vaginalis spcc417.12 protein, putative 0.0015 0.0009 0.0063
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0012 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0983 0.1995 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0033 0.0044 0.2265
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0028 0.0034 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0167 0.0321 0.0739
Loa Loa (eye worm) hypothetical protein 0.0082 0.0146 0.0729
Plasmodium vivax phosphoglycerate kinase, putative 0.0105 0.0193 1
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0017 0.0039
Schistosoma mansoni chromobox protein 0.0024 0.0028 0.0063
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0193
Plasmodium falciparum acyl-CoA synthetase 0.0024 0.0027 0.1349
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0012 0.0002 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0044 0.2302
Echinococcus granulosus tyrosine kinase 0.0028 0.0034 0.0034
Brugia malayi Bromodomain containing protein 0.0025 0.0029 0.0139
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0028 0.0189
Trypanosoma brucei pyruvate kinase 1, putative 0.0023 0.0026 0.0697
Echinococcus granulosus chromobox protein 1 0.0024 0.0028 0.0028
Echinococcus multilocularis PHD finger protein rhinoceros 0.002 0.0018 0.0018
Echinococcus multilocularis pyruvate kinase 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0027 0.0132
Echinococcus granulosus PHD finger protein rhinoceros 0.002 0.0018 0.0018
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0105 0.0193 1
Schistosoma mansoni tyrosine kinase 0.0028 0.0034 0.0079
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0022 0.0022 0.1013
Brugia malayi Guanylyl cyclase protein 23 0.0028 0.0034 0.0166
Onchocerca volvulus 0.0019 0.0017 0.0744
Brugia malayi Phosphoglycerate kinase 0.0105 0.0193 0.096
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0033 0.0044 0.0304
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0069 0.0118 0.0587
Entamoeba histolytica hypothetical protein 0.0013 0.0004 0.0182
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0047 0.0323
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0066 0.0114 0.3186
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0039 0.0058 0.0282
Entamoeba histolytica hypothetical protein 0.0043 0.0065 0.3333
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.0359 0.1793
Schistosoma mansoni metabotropic glutamate receptor 0.0248 0.0486 0.1117
Echinococcus multilocularis cpg binding protein 0.0041 0.0061 0.0061
Brugia malayi TAR-binding protein 0.0167 0.0321 0.1604
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0001 0.0001
Trichomonas vaginalis chromobox protein, putative 0.0015 0.0008 0.0053
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0065 0.0149
Brugia malayi nuclear hormone receptor 0.0019 0.0017 0.0078
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0268 0.0527 0.2636
Echinococcus multilocularis voltage dependent calcium channel subunit 0.2221 0.4536 0.4536
Loa Loa (eye worm) hypothetical protein 0.0082 0.0146 0.0729
Mycobacterium ulcerans carboxylesterase, LipT 0.0015 0.0009 0.0063
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0032 0.0044 0.0213
Echinococcus granulosus acetylcholinesterase 0.0091 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0179 0.0345 0.0793
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0173 0.0333 0.0765
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0105 0.0193 1
Schistosoma mansoni flap endonuclease-1 0.0017 0.0013 0.003
Onchocerca volvulus 0.0019 0.0017 0.0744
Giardia lamblia Phosphoglycerate kinase 0.0105 0.0193 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0048
Onchocerca volvulus Pyruvate kinase homolog 0.0023 0.0026 0.1187
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0006
Onchocerca volvulus 0.0036 0.0051 0.2463
Echinococcus multilocularis flap endonuclease 1 0.0019 0.0017 0.0017
Entamoeba histolytica hypothetical protein, conserved 0.0091 0.0164 0.8475
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0034 0.0168
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0022 0.0022 0.0103
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0165 0.038
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0017 0.0039
Plasmodium vivax flap endonuclease 1, putative 0.0019 0.0017 0.0797
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0017 0.008
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0019 0.0017 0.0017
Echinococcus multilocularis pyruvate kinase 0.0023 0.0026 0.0026
Loa Loa (eye worm) carboxylesterase 0.0091 0.0165 0.0823
Entamoeba histolytica pyruvate kinase, putative 0.0016 0.0011 0.0528
Schistosoma mansoni tar DNA-binding protein 0.0167 0.0321 0.0739
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0012 0.0002 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0167 0.0321 0.0739
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0025 0.1283
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0039 0.0057 0.1569
Onchocerca volvulus 0.0019 0.0017 0.0758
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0019 0.0017 0.0017
Echinococcus granulosus enteropeptidase 0.0019 0.0017 0.0017
Brugia malayi hypothetical protein 0.0085 0.0152 0.0756
Brugia malayi Zona pellucida-like domain containing protein 0.0091 0.0164 0.0813
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0051
Brugia malayi Inositol-1 0.0066 0.0114 0.0563
Schistosoma mansoni phosphoglycerate kinase 0.0105 0.0193 0.0443
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0018 0.0084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0022
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0028 0.0034 0.0034
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0033 0.0044 0.0304
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.1147 0.2332 0.5361
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0084
Onchocerca volvulus 0.0033 0.0044 0.2121
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0039 0.0057 0.1569
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0091 0.0164 0.0815
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0017 0.0012 0.0012
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0017 0.0758
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0019 0.0017 0.0451
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0022 0.0022 0.1148
Echinococcus multilocularis transcription factor Dp 1 0.0023 0.0024 0.0024
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0087 0.0156 0.4384
Schistosoma mansoni protein kinase 0.0028 0.0034 0.0079
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Schistosoma mansoni phosphoglycerate kinase 0.0105 0.0193 0.0443
Brugia malayi hypothetical protein 0.0021 0.002 0.0095
Echinococcus granulosus Mastin 0.0019 0.0017 0.0017
Plasmodium falciparum pyruvate kinase 2 0.0012 0.0002 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0038
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0029 0.0037 0.1759
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0017 0.0039
Brugia malayi mbt repeat family protein 0.0029 0.0037 0.0179
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.008
Loa Loa (eye worm) hypothetical protein 0.0091 0.0165 0.0823
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Onchocerca volvulus 0.0019 0.0017 0.0744
Entamoeba histolytica acyl-CoA synthetase, putative 0.0033 0.0044 0.2265
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0078
Echinococcus granulosus transcription factor Dp 1 0.0023 0.0024 0.0024
Loa Loa (eye worm) glutaminase 0.0723 0.1461 0.732
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0029 0.0142
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0031 0.0041 0.2115
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0031 0.0041 0.2045
Entamoeba histolytica hypothetical protein 0.0028 0.0034 0.1749
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0105
Echinococcus granulosus peregrin 0.0021 0.0021 0.0021
Loa Loa (eye worm) bromodomain containing protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Brugia malayi Carboxylesterase family protein 0.0015 0.0009 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0041
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0015 0.0009 0.0009
Brugia malayi hypothetical protein 0.0028 0.0034 0.0166
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0017 0.0017
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0024 0.0027 0.011
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0066 0.0114 0.0779
Loa Loa (eye worm) pyruvate kinase 0.0023 0.0026 0.0123
Echinococcus granulosus chromobox protein 1 0.0024 0.0028 0.0028
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0024 0.0026 0.0026
Onchocerca volvulus 0.0091 0.0164 0.8056
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0167 0.0321 0.1605
Brugia malayi jmjC domain containing protein 0.0065 0.011 0.0544
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0078
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0017 0.0758
Loa Loa (eye worm) hypothetical protein 0.0076 0.0133 0.0661
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0033 0.0044 0.0304
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0066 0.0114 0.5882
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0105 0.0193 1
Loa Loa (eye worm) carboxylesterase 0.0015 0.0009 0.0041
Mycobacterium ulcerans glutaminase 0.0723 0.1461 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0012 0.0002 0.0052
Echinococcus multilocularis acetylcholinesterase 0.0091 0.0165 0.0165
Loa Loa (eye worm) heterochromatin protein 1 0.0024 0.0028 0.0133
Schistosoma mansoni hypothetical protein 0.0032 0.0044 0.0101
Brugia malayi Carboxylesterase family protein 0.0091 0.0165 0.0821
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0028 0.0034 0.0034
Echinococcus multilocularis glycoprotein Antigen 5 0.0019 0.0017 0.0017
Trypanosoma brucei pyruvate kinase 1 0.0023 0.0026 0.0697
Trichomonas vaginalis pyruvate kinase, putative 0.0023 0.0026 0.0175
Schistosoma mansoni myelin transcription factor 1 myt1 0.0033 0.0045 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0017 0.0078
Loa Loa (eye worm) hypothetical protein 0.0091 0.0165 0.0823
Echinococcus multilocularis enteropeptidase 0.0019 0.0017 0.0017
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0034 0.0047 0.1305
Entamoeba histolytica Ran family GTPase 0.0012 0.0002 0.0052
Leishmania major GTP-binding protein, putative 0.0012 0.0002 0.0028
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0105 0.0193 0.5417
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0061 0.0301
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0359 0.0359
Echinococcus multilocularis pyruvate kinase 0.0012 0.0002 0.0002
Brugia malayi Carboxylesterase family protein 0.0015 0.0009 0.0039
Echinococcus multilocularis histone acetyltransferase MYST2 0.0033 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0051
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0017 0.0017
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.011 0.0203 0.1009
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0033 0.0162
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0078
Brugia malayi RNA, U transporter 1 0.0046 0.0072 0.0354
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0012 0.0002 0.0087
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0039 0.0058 0.1602
Onchocerca volvulus 0.0091 0.0164 0.8056
Giardia lamblia Pyruvate kinase 0.0023 0.0026 0.1253
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0359 0.0826
Loa Loa (eye worm) hypothetical protein 0.0091 0.0164 0.0815
Leishmania major squalene synthase, putative 0.007 0.0121 0.3384
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0017 0.0039
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.0176 0.9149
Brugia malayi mbt repeat family protein 0.0029 0.0037 0.0179
Loa Loa (eye worm) CUTiclin family member 0.0091 0.0164 0.0815
Trypanosoma cruzi phytoene synthase, putative 0.0022 0.0022 0.0599
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0091 0.0164 0.0813
Onchocerca volvulus 0.0015 0.0009 0.0367
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0017 0.0078
Onchocerca volvulus 0.0028 0.0034 0.1628
Toxoplasma gondii histone lysine methyltransferase SET1 0.0072 0.0125 0.6485
Brugia malayi Trypsin family protein 0.0019 0.0017 0.0076
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.002 0.0018 0.0041
Echinococcus granulosus zinc finger protein 0.0015 0.0008 0.0008
Leishmania major phosphoglycerate kinase B, cytosolic 0.0105 0.0193 0.5417
Schistosoma mansoni pyruvate kinase 0.0023 0.0026 0.0059
Brugia malayi Zona pellucida-like domain containing protein 0.0091 0.0164 0.0813
Onchocerca volvulus Poor gastrulation protein homolog 0.0048 0.0076 0.3691
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0066 0.0114 0.0779
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0025 0.1283
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0017 0.0017
Plasmodium vivax importin-beta 2, putative 0.0016 0.0011 0.0473
Brugia malayi von Willebrand factor type A domain containing protein 0.0091 0.0164 0.0813
Onchocerca volvulus 0.0055 0.0091 0.4419
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0085 0.0152 0.0758

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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