Detailed information for compound 757962

Basic information

Technical information
  • TDR Targets ID: 757962
  • Name: cyclopentyl N-(1,1,1,3,3,3-hexafluoropropan-2 -yl)carbamate
  • MW: 279.18 | Formula: C9H11F6NO2
  • H donors: 1 H acceptors: 1 LogP: 3.51 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(OC1CCCC1)NC(C(F)(F)F)C(F)(F)F
  • InChi: 1S/C9H11F6NO2/c10-8(11,12)6(9(13,14)15)16-7(17)18-5-3-1-2-4-5/h5-6H,1-4H2,(H,16,17)
  • InChiKey: TZAISGSBDSYNKI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • cyclopentyl N-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]carbamate
  • N-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]carbamic acid cyclopentyl ester
  • IDI1_021507
  • ChemDiv3_003597

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0052 0.0123 0.0093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0074 0.0152
Plasmodium vivax importin-beta 2, putative 0.0033 0.003 0.0082
Echinococcus granulosus survival motor neuron protein 1 0.0981 0.4672 0.4655
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0074 0.0071
Brugia malayi follicle stimulating hormone receptor 0.0519 0.241 0.5156
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Echinococcus granulosus jumonji domain containing protein 0.0082 0.027 0.0241
Schistosoma mansoni hypothetical protein 0.2071 1 1
Mycobacterium leprae Probable lipase LipE 0.0114 0.0431 1
Onchocerca volvulus 0.0064 0.0183 0.1093
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0074 0.0044
Loa Loa (eye worm) histone methyltransferase 0.0045 0.0091 0.0185
Loa Loa (eye worm) thyroglobulin type-1 repeat family protein 0.0064 0.0183 0.0382
Schistosoma mansoni survival motor neuron protein 0.02 0.085 0.0848
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0033 0.0032 0.0002
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0197 0.0194
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.007 0.1551
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0229 0.0456
Brugia malayi PHD-finger family protein 0.0084 0.028 0.0594
Loa Loa (eye worm) heterochromatin protein 1 0.0145 0.0582 0.1237
Brugia malayi Bromodomain containing protein 0.0235 0.1022 0.2183
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0004 0.0015
Brugia malayi Bm-MIF-1, identical 0.0587 0.274 0.5863
Mycobacterium tuberculosis Probable esterase LipL 0.0114 0.0431 0.1122
Mycobacterium tuberculosis Conserved protein 0.0114 0.0431 0.1122
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0158 0.0472
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0229 0.0837
Brugia malayi Thyroglobulin type-1 repeat family protein 0.0064 0.0183 0.0385
Brugia malayi steroid hormone receptor 0.0041 0.0074 0.0152
Loa Loa (eye worm) hypothetical protein 0.0033 0.003 0.0056
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0114 0.0431 0.0428
Schistosoma mansoni alpha glucosidase 0.0073 0.0229 0.0227
Schistosoma mansoni hypothetical protein 0.02 0.085 0.0848
Trichomonas vaginalis macrophage migration inhibitory factor, mif, putative 0.0587 0.274 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.007 0.1545
Brugia malayi CHD4 protein 0.0038 0.0056 0.0114
Schistosoma mansoni cpg binding protein 0.0159 0.0651 0.0648
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0074 0.0149
Onchocerca volvulus 0.0051 0.012 0.0713
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.007 0.004
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.018 0.0752 0.0724
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0197 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.1604 0.5853
Plasmodium falciparum importin beta, putative 0.0033 0.003 0.0082
Echinococcus multilocularis microtubule associated protein 2 0.1399 0.6714 0.6704
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0074 0.0152
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0004 0.0015
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.012 0.046 0.0431
Onchocerca volvulus Alhambra homolog 0.0059 0.0158 0.0943
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0074 0.0149
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0074 0.0152
Brugia malayi chromobox protein homolog 3 0.0081 0.0269 0.0571
Trichomonas vaginalis chromobox protein, putative 0.0145 0.0582 0.2123
Mycobacterium ulcerans lipase LipD 0.0114 0.0431 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0064 0.0183 0.0383
Toxoplasma gondii ABC1 family protein 0.0114 0.0431 0.1478
Schistosoma mansoni smad1 5 8 and 0.0042 0.0075 0.0073
Brugia malayi CXXC zinc finger family protein 0.0145 0.0582 0.1241
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.007 0.0139
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0074 0.0071
Brugia malayi Glycosyl hydrolases family 31 protein 0.0073 0.0229 0.0485
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.007 0.1627
Echinococcus granulosus geminin 0.1233 0.59 0.5888
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0074 0.0044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0189 0.0795 0.0767
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Onchocerca volvulus Huntingtin homolog 0.0124 0.0475 0.2868
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0336 0.1515 0.324
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.007 0.004
Trypanosoma brucei ISWI complex protein 0.0046 0.0097 0.2181
Trichomonas vaginalis chromobox protein, putative 0.0088 0.03 0.1093
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0074 0.0044
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0158 0.0472
Brugia malayi Thyroglobulin type-1 repeat family protein 0.0064 0.0183 0.0385
Brugia malayi RNA, U transporter 1 0.0093 0.0324 0.0689
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0074 0.0149
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0197 0.0194
Echinococcus granulosus fetal alzheimer antigen falz 0.0077 0.0245 0.0215
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.03 0.1337 0.2661
Giardia lamblia Macrophage migration inhibitory factor 0.0587 0.274 0.5389
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0074 0.0044
Echinococcus granulosus Smad4 0.0042 0.0075 0.0045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0074 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.0114 0.0431 1
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.2377 0.8675
Loa Loa (eye worm) isocitrate dehydrogenase 0.0063 0.0178 0.0373
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0431 1
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.2377 0.8675
Schistosoma mansoni tar DNA-binding protein 0.0335 0.151 0.1508
Loa Loa (eye worm) hypothetical protein 0.0364 0.165 0.3526
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0178 0.0547
Trypanosoma cruzi ISWI complex protein 0.0046 0.0097 0.2257
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0109 0.0403 0.0374
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0123 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0148 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.012 0.046 0.0431
Mycobacterium tuberculosis Probable hydrolase 0.0114 0.0431 0.1122
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0074 0.0149
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0055 0.0139 0.0109
Brugia malayi Smad1 0.0042 0.0075 0.0156
Loa Loa (eye worm) RNA binding protein 0.0335 0.151 0.3227
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0062 0.0225
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.007 0.0068
Brugia malayi beta-lactamase family protein 0.0114 0.0431 0.0917
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.007 0.014
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0004 0.0015
Schistosoma mansoni smad1 5 8 and 0.0042 0.0075 0.0073
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.007 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0153 0.0558
Loa Loa (eye worm) hypothetical protein 0.0064 0.0183 0.0382
Schistosoma mansoni importin beta-1 0.0033 0.003 0.0028
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0114 0.0431 0.1122
Plasmodium falciparum macrophage migration inhibitory factor 0.0587 0.274 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0033 0.0032 0.0002
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1054 0.5024 1
Schistosoma mansoni zinc finger protein 0.0046 0.0097 0.0095
Schistosoma mansoni jumonji/arid domain-containing protein 0.0085 0.0287 0.0285
Schistosoma mansoni alpha-glucosidase 0.0284 0.1262 0.1259
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0074 0.0152
Onchocerca volvulus 0.0299 0.1334 0.8081
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0004 0.001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0348 0.1574 0.3363
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0074 0.0071
Brugia malayi jmjC domain containing protein 0.0085 0.0287 0.061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0336 0.1515 0.1489
Schistosoma mansoni inositol monophosphatase 0.0041 0.007 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Brugia malayi Isocitrate dehydrogenase 0.0063 0.0178 0.0377
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0075 0.0153
Onchocerca volvulus 0.0191 0.0805 0.4873
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0114 0.0431 0.0914
Brugia malayi hypothetical protein 0.0124 0.0475 0.1012
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0229 0.0837
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.027 0.0241
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.007 0.0256
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0218 0.0189
Onchocerca volvulus 0.0064 0.0183 0.1093
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0075 0.0045
Echinococcus multilocularis peregrin 0.0066 0.0193 0.0163
Loa Loa (eye worm) hypothetical protein 0.0116 0.0439 0.0931
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1515 0.553
Schistosoma mansoni hypothetical protein 0.0389 0.1775 0.1773
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0336 0.1515 0.1489
Leishmania major hypothetical protein, conserved 0.0046 0.0097 0.0355
Echinococcus granulosus microtubule associated protein 2 0.1399 0.6714 0.6704
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0431 0.1572
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0063 0.0178 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0269 0.0983
Brugia malayi hypothetical protein 0.0981 0.4672 1
Brugia malayi PHD-finger family protein 0.0059 0.0158 0.0333
Loa Loa (eye worm) hypothetical protein 0.0299 0.1334 0.2849
Schistosoma mansoni tar DNA-binding protein 0.0335 0.151 0.1508
Brugia malayi nuclear hormone receptor 0.0041 0.0074 0.0152
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0229 0.0837
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0074 0.0149
Loa Loa (eye worm) hypothetical protein 0.0114 0.0431 0.0914
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.0091 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0153 0.0558
Brugia malayi RNA binding protein 0.0335 0.151 0.323
Schistosoma mansoni smad 0.0042 0.0075 0.0073
Echinococcus multilocularis neuropeptide receptor A26 0.0514 0.2385 0.2362
Loa Loa (eye worm) hypothetical protein 0.0214 0.0918 0.1958
Trichomonas vaginalis chromobox protein, putative 0.0088 0.03 0.1093
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0004 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0004 0.0015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0109 0.0403 0.0374
Echinococcus multilocularis neuropeptide s receptor 0.0514 0.2385 0.2362
Entamoeba histolytica hypothetical protein 0.012 0.046 0.0915
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.018 0.0752 0.0724
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Entamoeba histolytica hypothetical protein 0.012 0.046 0.0915
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0178 0.0149
Toxoplasma gondii histone lysine methyltransferase SET1 0.0283 0.1253 0.4513
Echinococcus multilocularis chromobox protein 1 0.0145 0.0582 0.0553
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0038 0.0056 0.0053
Loa Loa (eye worm) hypothetical protein 0.0101 0.0363 0.0769
Loa Loa (eye worm) bromodomain containing protein 0.0053 0.0132 0.0274
Schistosoma mansoni chromobox protein 0.0145 0.0582 0.0579
Schistosoma mansoni coup transcription factor 0.0041 0.0074 0.0071
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0731 0.3448 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.0063
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0074 0.0044
Loa Loa (eye worm) hypothetical protein 0.018 0.0752 0.1603
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0074 0.0071
Leishmania major macrophage migration inhibitory factor-like protein 0.0587 0.274 1
Brugia malayi MH1 domain containing protein 0.0042 0.0075 0.0156
Echinococcus granulosus chromobox protein 1 0.0145 0.0582 0.0553
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0114 0.0431 0.1122
Echinococcus granulosus neuropeptide s receptor 0.0514 0.2385 0.2362
Leishmania major macrophage migration inhibitory factor-like protein 0.0587 0.274 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1487 0.1461
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1515 0.553
Schistosoma mansoni bromodomain containing protein 0.02 0.0848 0.0846
Leishmania major alpha glucosidase II subunit, putative 0.0073 0.0229 0.0837
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0074 0.0149
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0336 0.1515 0.1489
Entamoeba histolytica hypothetical protein 0.03 0.1337 0.2661
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0197 0.3513
Loa Loa (eye worm) hypothetical protein 0.0041 0.007 0.0142
Brugia malayi beta-lactamase 0.0114 0.0431 0.0917
Onchocerca volvulus 0.0064 0.0183 0.1096
Schistosoma mansoni hypothetical protein 0.0046 0.0097 0.0095
Onchocerca volvulus 0.0064 0.0183 0.1093
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0197 0.0718
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0336 0.1515 0.1513
Loa Loa (eye worm) Smad1 0.0042 0.0075 0.0153
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0176 0.0368
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.007 0.0256
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0074 0.0044
Echinococcus granulosus GPCR family 2 0.018 0.0752 0.0724
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0229 0.0456
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0512 0.2377 0.5083
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0074 0.0071
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.007 0.0257
Giardia lamblia PHD finger protein 15 0.0059 0.0158 0.0177
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0075 0.0073
Schistosoma mansoni hypothetical protein 0.018 0.0752 0.075
Echinococcus granulosus tumor protein p63 0.0348 0.1575 0.1549
Giardia lamblia DNA repair protein RAD52 0.1054 0.5024 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.033 0.1487 0.3179
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0074 0.0152
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0074 0.0071
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0178 0.0547
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0114 0.0431 0.0428
Trichomonas vaginalis penicillin-binding protein, putative 0.0114 0.0431 0.1572
Echinococcus granulosus histone lysine methyltransferase setb 0.0055 0.0139 0.0109
Loa Loa (eye worm) beta-lactamase 0.0114 0.0431 0.0914
Brugia malayi secreted modular calcium-binding protein 1 0.0064 0.0183 0.0385
Echinococcus granulosus smad 0.0042 0.0075 0.0045
Schistosoma mansoni hypothetical protein 0.0059 0.0158 0.0155
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.012 0.0118
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0004 0.0015
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.007 0.004
Brugia malayi Bromodomain containing protein 0.0066 0.0193 0.0408
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0464 0.0985
Schistosoma mansoni hypothetical protein 0.1233 0.59 0.5899
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0074 0.0044
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0074 0.0044
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.007 0.0147
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0178 0.4143
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0074 0.0044
Echinococcus multilocularis survival motor neuron protein 1 0.0981 0.4672 0.4655
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0073 0.0268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0074 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0229 0.0837
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0074 0.0071
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0038 0.0056 0.0026
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0075 0.0045
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0063 0.0178 0.0624
Mycobacterium ulcerans hypothetical protein 0.0114 0.0431 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.012 0.0248
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0148 0.0541
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0229 0.5324
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0073 0.0229 0.0482
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0431 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0036 0.0047 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0587 0.274 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0074 0.0152
Schistosoma mansoni hypothetical protein 0.018 0.0752 0.075
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0397 0.1811 0.3873
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0074 0.0044
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0158 0.0329
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.2377 0.8675
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0004 0.0015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0519 0.241 0.5154
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0074 0.0071
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.007 0.1627
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0063 0.0178 0.0624
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0269 0.0983
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.007 0.0256
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0148 0.0541
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.033 0.1487 0.3176
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0336 0.1515 0.1513
Brugia malayi ecdysteroid receptor 0.0041 0.0074 0.0152
Brugia malayi nuclear receptor NHR-88 0.0041 0.0074 0.0152
Echinococcus multilocularis GPCR, family 2 0.018 0.0752 0.0724
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.018 0.0752 0.1606
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0386 0.1758 0.6415
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0148 0.0541
Mycobacterium ulcerans beta-lactamase 0.0114 0.0431 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0073 0.0229 0.0837
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.007 0.0256
Brugia malayi latrophilin 2 splice variant baaae 0.0389 0.1775 0.3797
Schistosoma mansoni jumonji domain containing protein 0.0153 0.0618 0.0616
Loa Loa (eye worm) hypothetical protein 0.0389 0.1775 0.3795
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0192 0.0812 0.0784
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.003 0.0609
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Toxoplasma gondii macrophage migration inhibitory factor, putative 0.0587 0.274 1
Echinococcus multilocularis snurportin 1 0.0348 0.1574 0.1548
Schistosoma mansoni inositol monophosphatase 0.0041 0.007 0.0068
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0114 0.0431 1
Echinococcus granulosus cpg binding protein 0.0159 0.0651 0.0622
Onchocerca volvulus 0.0114 0.0431 0.2598
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0229 0.5324
Loa Loa (eye worm) TAR-binding protein 0.0335 0.151 0.3227
Onchocerca volvulus Glucosylceramidase homolog 0.0336 0.1515 0.9181
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Brugia malayi MH2 domain containing protein 0.0615 0.2877 0.6157
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0055 0.0139 0.0136
Schistosoma mansoni cpg binding protein 0.0145 0.0582 0.0579
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0114 0.0431 0.1122
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0197 0.3513
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0077 0.0245 0.0243
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.2377 0.8675
Schistosoma mansoni zinc finger protein 0.0068 0.0201 0.0199
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0074 0.0152
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.2377 0.8675
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1515 0.553
Mycobacterium tuberculosis Conserved protein 0.0114 0.0431 0.1122
Trichomonas vaginalis maltase-glucoamylase, putative 0.0073 0.0229 0.0837
Echinococcus multilocularis cpg binding protein 0.0159 0.0651 0.0622
Onchocerca volvulus Huntingtin homolog 0.0124 0.0475 0.2868
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.018 0.0752 0.0724
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0148 0.0541
Loa Loa (eye worm) hypothetical protein 0.0137 0.0543 0.1154
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1515 0.553
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0074 0.0071
Echinococcus granulosus zinc finger protein 0.0068 0.0201 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.1604 0.5853
Brugia malayi hypothetical protein 0.012 0.046 0.0979
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.057 0.2657 0.5685
Loa Loa (eye worm) CHromoDomain protein family member 0.0038 0.0056 0.0111
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0074 0.0071
Brugia malayi MH1 domain containing protein 0.0042 0.0075 0.0156
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.007 0.0068
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1776 0.8558 0.8554
Loa Loa (eye worm) hypothetical protein 0.0055 0.0139 0.0288
Echinococcus multilocularis zinc finger protein 0.0068 0.0201 0.0171
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0077 0.0245 0.0215
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.007 0.0257
Brugia malayi N-terminal motif family protein 0.0364 0.165 0.3528
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0229 0.0837
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0178 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0004 0.0015
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0158 0.0155
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0074 0.0044
Schistosoma mansoni tar DNA-binding protein 0.0335 0.151 0.1508
Trypanosoma cruzi ISWI complex protein 0.0046 0.0097 0.2257
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.02 0.085 0.1815
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0074 0.0152
Echinococcus multilocularis smad 0.0042 0.0075 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0073 0.0268
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0004 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0074 0.0152
Loa Loa (eye worm) hypothetical protein 0.0123 0.0474 0.1006
Trichomonas vaginalis helicase, putative 0.0033 0.0032 0.0116
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.018 0.0752 0.0724
Schistosoma mansoni hypothetical protein 0.0062 0.0176 0.0174
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0158 0.0549
Brugia malayi RNA recognition motif domain containing protein 0.0335 0.151 0.323
Brugia malayi jmjC domain containing protein 0.0192 0.0812 0.1733
Loa Loa (eye worm) hypothetical protein 0.0081 0.0269 0.0568
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0192 0.0812 0.0784
Leishmania major hypothetical protein, conserved 0.0114 0.0431 0.1572
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1515 0.553
Loa Loa (eye worm) macrophage migration inhibitory factor 0.0587 0.274 0.5861
Loa Loa (eye worm) hypothetical protein 0.0114 0.0431 0.0914
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0074 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0074 0.0152
Onchocerca volvulus 0.0114 0.0431 0.2598
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0063 0.0178 0.038
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0063 0.0178 0.4143
Schistosoma mansoni hypothetical protein 0.1233 0.59 0.5899
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.007 0.004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0336 0.1515 0.3237
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0047 0.0017
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.0292 0.1301 0.2778
Loa Loa (eye worm) hypothetical protein 0.0114 0.0431 0.0914
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.003 0.0609
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0335 0.151 0.3227
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0197 0.0615
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1515 0.553
Brugia malayi isocitrate dehydrogenase 0.0063 0.0178 0.0377
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0004 0.0015
Mycobacterium tuberculosis Probable lipase LipD 0.0114 0.0431 0.1122
Mycobacterium tuberculosis Probable lipase LipE 0.0114 0.0431 0.1122
Loa Loa (eye worm) pigment dispersing factor receptor c 0.057 0.2657 0.5683
Loa Loa (eye worm) hypothetical protein 0.057 0.2657 0.5683
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.007 0.0145
Loa Loa (eye worm) hypothetical protein 0.0124 0.0475 0.1009
Plasmodium vivax macrophage migration inhibitory factor, putative 0.0587 0.274 1
Loa Loa (eye worm) inositol-1 0.0041 0.007 0.0141
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0075 0.0045
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.007 0.004
Echinococcus granulosus chromobox protein 1 0.0145 0.0582 0.0553
Schistosoma mansoni cpg binding protein 0.0159 0.0651 0.0648
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.007 0.0257
Brugia malayi PHD-finger family protein 0.0033 0.0033 0.0066
Echinococcus granulosus beta LACTamase domain containing family member 0.0114 0.0431 0.0402
Echinococcus granulosus neutral alpha glucosidase AB 0.0073 0.0229 0.02
Brugia malayi beta-lactamase family protein 0.0114 0.0431 0.0917
Brugia malayi Calcitonin receptor-like protein seb-1 0.057 0.2657 0.5685
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0038 0.0056 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0336 0.1515 0.1489
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.007 0.1633
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0088 0.03 0.1803
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0075 0.0045
Mycobacterium tuberculosis Conserved protein 0.0114 0.0431 0.1122
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0229 0.0837
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0178 0.4086
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Trypanosoma brucei hypothetical protein, conserved 0.0114 0.0431 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0073 0.0229 0.0735
Echinococcus multilocularis neutral alpha glucosidase AB 0.0073 0.0229 0.02
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.1515 0.553
Loa Loa (eye worm) hypothetical protein 0.0397 0.1811 0.387
Trypanosoma brucei glucosidase, putative 0.0073 0.0229 0.5278
Echinococcus granulosus methyl CpG binding domain protein 2 0.0052 0.0123 0.0093
Brugia malayi MH2 domain containing protein 0.0042 0.0075 0.0156
Echinococcus multilocularis tar DNA binding protein 0.0335 0.151 0.1485
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0063 0.0178 0.0176
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0074 0.0044
Loa Loa (eye worm) hypothetical protein 0.0114 0.0431 0.0914
Schistosoma mansoni jumonji/arid domain-containing protein 0.0085 0.0287 0.0285
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.007 0.0257
Entamoeba histolytica macrophage migration inhibitory factor-like protein 0.0587 0.274 0.5453
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0512 0.2377 0.5085
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0229 0.0837
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.007 0.004
Loa Loa (eye worm) jmjC domain-containing protein 0.0085 0.0287 0.0606
Mycobacterium leprae conserved hypothetical protein 0.0114 0.0431 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.018 0.0752 0.1603
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.0292 0.1301 0.2778
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0074 0.0071
Schistosoma mansoni alpha-glucosidase 0.0284 0.1262 0.1259
Loa Loa (eye worm) hypothetical protein 0.0064 0.0183 0.0382
Trichomonas vaginalis chromobox protein, putative 0.0145 0.0582 0.2123
Schistosoma mansoni smad1 5 8 and 0.0042 0.0075 0.0073
Brugia malayi TAR-binding protein 0.0335 0.151 0.323
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0308 0.1379 0.1377
Trichomonas vaginalis glucosylceramidase, putative 0.0512 0.2377 0.8675
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0431 0.1572
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0047 0.0017
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0004 0.0097
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0074 0.0431
Loa Loa (eye worm) hypothetical protein 0.0114 0.0431 0.0914
Onchocerca volvulus 0.0145 0.0582 0.3516
Onchocerca volvulus 0.0041 0.0074 0.0431
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0364 0.165 1
Brugia malayi Latrophilin receptor protein 2 0.018 0.0752 0.1606
Schistosoma mansoni microtubule-associated protein tau 0.1399 0.6714 0.6713
Echinococcus granulosus tar DNA binding protein 0.0335 0.151 0.1485
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0148 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0032 0.0116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0148 0.0541
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0074 0.0152
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0178 0.0149
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.007 0.1633
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0114 0.0431 0.0917
Loa Loa (eye worm) hypothetical protein 0.0064 0.0183 0.0382
Echinococcus granulosus lysosomal alpha glucosidase 0.033 0.1487 0.1461
Loa Loa (eye worm) hypothetical protein 0.0059 0.0158 0.0329
Echinococcus granulosus neuropeptide receptor A26 0.0514 0.2385 0.2362
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0074 0.0431
Brugia malayi Thyroglobulin type-1 repeat family protein 0.0064 0.0183 0.0385
Echinococcus multilocularis tumor protein p63 0.0348 0.1575 0.1549
Brugia malayi MH2 domain containing protein 0.0042 0.0075 0.0156
Brugia malayi Importin beta-1 subunit 0.0033 0.003 0.0059
Schistosoma mansoni Smad4 0.0042 0.0075 0.0073
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0074 0.0044
Schistosoma mansoni hypothetical protein 0.018 0.0752 0.075
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0123 0.0121
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0074 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0074 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0074 0.0152
Brugia malayi Heterochromatin protein 1 0.0145 0.0582 0.124
Brugia malayi F/Y-rich N-terminus family protein 0.0069 0.021 0.0444
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0197 0.0167
Echinococcus multilocularis dnaJ subfamily B 0.2071 1 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0075 0.0153
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Schistosoma mansoni hypothetical protein 0.0348 0.1574 0.1572
Schistosoma mansoni chromobox protein 0.0145 0.0582 0.0579
Schistosoma mansoni hypothetical protein 0.012 0.046 0.0457
Schistosoma mansoni transcription factor LCR-F1 0.012 0.046 0.0457
Echinococcus multilocularis isocitrate dehydrogenase 0.0063 0.0178 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0074 0.0152
Echinococcus granulosus lysine specific demethylase 5A 0.0085 0.0287 0.0258
Loa Loa (eye worm) thyroglobulin type-1 repeat family protein 0.0064 0.0183 0.0382
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Onchocerca volvulus 0.0064 0.0183 0.1093
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0081 0.0269 0.1619
Loa Loa (eye worm) hypothetical protein 0.0064 0.0183 0.0382
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0074 0.0431
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0158 0.0128
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0004 0.0097
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0158 0.0128
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.007 0.004
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0197 0.0167
Loa Loa (eye worm) CXXC zinc finger family protein 0.0145 0.0582 0.1238
Trichomonas vaginalis esterase, putative 0.0114 0.0431 0.1572
Brugia malayi hypothetical protein 0.0299 0.1334 0.2851
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0074 0.0149
Brugia malayi Inositol-1 0.0041 0.007 0.0145
Echinococcus multilocularis Smad4 0.0042 0.0075 0.0045
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1487 0.1461
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0197 0.3513
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0336 0.1515 0.1513
Echinococcus multilocularis beta LACTamase domain containing family member 0.0114 0.0431 0.0402
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0431 0.1572
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0074 0.0152
Loa Loa (eye worm) hypothetical protein 0.0114 0.0431 0.0914
Echinococcus granulosus snurportin 1 0.0348 0.1574 0.1548
Echinococcus granulosus peregrin 0.0066 0.0193 0.0163
Echinococcus multilocularis chromobox protein 1 0.0145 0.0582 0.0553
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0189 0.0795 0.0767
Onchocerca volvulus 0.02 0.085 0.5143
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0148 0.0541
Entamoeba histolytica hypothetical protein 0.012 0.046 0.0915
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0074 0.0044
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0178 0.0651
Echinococcus multilocularis geminin 0.1233 0.59 0.5888
Plasmodium falciparum phd finger protein, putative 0.0059 0.0158 0.0549
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0074 0.0152
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0074 0.0044
Schistosoma mansoni tar DNA-binding protein 0.0335 0.151 0.1508
Plasmodium vivax hypothetical protein, conserved 0.0114 0.0431 0.1547
Loa Loa (eye worm) MH2 domain-containing protein 0.0615 0.2877 0.6156
Trichomonas vaginalis penicillin-binding protein, putative 0.0114 0.0431 0.1572
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0055 0.0141 0.0139
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.007 0.5
Schistosoma mansoni tar DNA-binding protein 0.0335 0.151 0.1508
Entamoeba histolytica hypothetical protein 0.012 0.046 0.0915
Loa Loa (eye worm) hypothetical protein 0.0981 0.4672 1
Schistosoma mansoni hypothetical protein 0.018 0.0752 0.075
Echinococcus granulosus mixed lineage leukemia protein mll 0.0036 0.0047 0.0017
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0063 0.0178 0.0149
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0063 0.0178 0.4086
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.0091 0.0061
Loa Loa (eye worm) hypothetical protein 0.0124 0.0475 0.1009
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Loa Loa (eye worm) transcription factor SMAD2 0.0615 0.2877 0.6156
Onchocerca volvulus 0.0114 0.0431 0.2598
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0074 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0055 0.0139 0.0136
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0149
Brugia malayi Bromodomain containing protein 0.0116 0.0438 0.0932

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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