Detailed information for compound 790253

Basic information

Technical information
  • TDR Targets ID: 790253
  • Name: 4-(4-chloro-5-methyl-3-nitropyrazol-1-yl)-N-( 3-cyano-4-ethyl-5-methylthiophen-2-yl)butanam ide
  • MW: 395.864 | Formula: C16H18ClN5O3S
  • H donors: 1 H acceptors: 5 LogP: 4 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1c(NC(=O)CCCn2nc(c(c2C)Cl)[N+](=O)[O-])sc(c1CC)C
  • InChi: 1S/C16H18ClN5O3S/c1-4-11-10(3)26-16(12(11)8-18)19-13(23)6-5-7-21-9(2)14(17)15(20-21)22(24)25/h4-7H2,1-3H3,(H,19,23)
  • InChiKey: QWBGJPMBALGIKT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(4-chloro-5-methyl-3-nitro-pyrazol-1-yl)-N-(3-cyano-4-ethyl-5-methyl-2-thienyl)butanamide
  • 4-(4-chloro-5-methyl-3-nitro-1-pyrazolyl)-N-(3-cyano-4-ethyl-5-methyl-2-thienyl)butanamide
  • 4-(4-chloro-5-methyl-3-nitro-pyrazol-1-yl)-N-(3-cyano-4-ethyl-5-methyl-2-thienyl)butyramide
  • 4-(4-chloro-5-methyl-3-nitro-pyrazol-1-yl)-N-(3-cyano-4-ethyl-5-methyl-thiophen-2-yl)butanamide
  • EU-0089207
  • ZINC02431306

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Muscleblind-like protein 0.0924 0.5689 1
Trichomonas vaginalis beta lactamase domain, putative 0.0034 0.014 0.0784
Echinococcus granulosus kelch ECH associated protein 1 like 0.0298 0.1785 0.3138
Plasmodium vivax DNA repair protein REV1, putative 0.0018 0.004 0.0172
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0034 0.014 0.014
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0102 0.018
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0058 0.0664
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0247 0.1469 0.515
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0248 0.1387
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Trypanosoma brucei unspecified product 0.0058 0.0289 0.1256
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0582 0.3556 0.8226
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0335 0.18
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0034 0.014 0.0784
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0398 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0034 0.0034
Brugia malayi Cytochrome P450 family protein 0.0048 0.0228 0.0402
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0089 0.0246
Plasmodium vivax unspecified product 0.0034 0.014 0.292
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0034 0.0086
Onchocerca volvulus 0.0017 0.0034 0.0086
Onchocerca volvulus 0.0034 0.014 0.036
Entamoeba histolytica protein kinase domain containing protein 0.0013 0.0009 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0289 0.1556
Schistosoma mansoni hypothetical protein 0.0299 0.179 0.6279
Loa Loa (eye worm) ctsf protein 0.0017 0.0034 0.0059
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Echinococcus granulosus ferritin 0.0027 0.0094 0.0166
Brugia malayi jmjC domain containing protein 0.0033 0.013 0.0229
Echinococcus granulosus survival motor neuron protein 1 0.049 0.2983 0.5244
Plasmodium falciparum importin beta, putative 0.0028 0.0105 0.1944
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.049 0.2983 0.5244
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.0787 0.1383
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0034 0.014 0.0753
Entamoeba histolytica type A flavoprotein, putative 0.0034 0.014 0.0784
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0236 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Entamoeba histolytica hypothetical protein 0.0037 0.0156 0.0874
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.085 0.4754
Brugia malayi Smad1 0.0025 0.0086 0.0151
Onchocerca volvulus Huntingtin homolog 0.0136 0.0773 0.1985
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0248 0.1387
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0296 0.1594
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0089 0.0573
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0094 0.0526
Echinococcus multilocularis ETS transcription factor Elf 5 0.0022 0.0067 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Brugia malayi MH1 domain containing protein 0.0025 0.0086 0.0151
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0086 0.0151
Brugia malayi Cathepsin L-like precursor 0.0017 0.0034 0.0059
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0089 0.0477
Schistosoma mansoni smad1 5 8 and 0.0025 0.0086 0.0301
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0028 0.005
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0094 0.0094
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0028 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.0034 0.014 0.0246
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0248 0.1333
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0248 0.1333
Mycobacterium ulcerans hypothetical protein 0.0034 0.014 0.0235
Onchocerca volvulus 0.0017 0.0034 0.0086
Entamoeba histolytica alkyl sulfatase, putative 0.0034 0.014 0.0784
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.005
Entamoeba histolytica hypothetical protein, conserved 0.0034 0.014 0.0784
Loa Loa (eye worm) ets-domain-containing protein 0.0022 0.0067 0.0118
Trypanosoma cruzi glyoxalase II 0.0034 0.014 0.0753
Schistosoma mansoni flap endonuclease-1 0.0024 0.0078 0.0274
Echinococcus multilocularis snurportin 1 0.0303 0.1817 0.1817
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0156 0.084
Mycobacterium tuberculosis Possible hydrolase 0.0034 0.014 0.0109
Schistosoma mansoni hypothetical protein 0.034 0.2047 0.7179
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0105 0.0325
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.01 0.0176
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0055 0.031
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0332 0.1782
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.072 0.2524
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.0787 0.1383
Toxoplasma gondii histone lysine methyltransferase SET1 0.0172 0.0998 1
Schistosoma mansoni tsg101-related 0.0183 0.1067 0.374
Entamoeba histolytica type A flavoprotein, putative 0.0034 0.014 0.0784
Entamoeba histolytica serine/threonine protein kinase, putative 0.0298 0.1788 1
Schistosoma mansoni ferritin 0.0027 0.0094 0.0331
Echinococcus multilocularis ets variant gene 4 0.0022 0.0067 0.0067
Echinococcus multilocularis ETS transcription factor Elf 1 0.0022 0.0067 0.0067
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0034 0.014 0.0784
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0059
Schistosoma mansoni ran 0.0021 0.0058 0.0203
Leishmania major hypothetical protein, conserved 0.0034 0.014 0.0753
Echinococcus multilocularis Kelch repeat type 1 0.0299 0.179 0.179
Trichomonas vaginalis beta lactamase domain, putative 0.0034 0.014 0.0784
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0055 0.031
Schistosoma mansoni smad1 5 8 and 0.0025 0.0086 0.0301
Echinococcus granulosus muscleblind protein 0.0924 0.5689 1
Entamoeba histolytica hypothetical protein 0.0023 0.0071 0.0397
Loa Loa (eye worm) hypothetical protein 0.0034 0.014 0.0246
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Brugia malayi hypothetical protein 0.0034 0.014 0.0246
Onchocerca volvulus 0.0017 0.0034 0.0086
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0398 0.0841
Brugia malayi hypothetical protein 0.0219 0.1295 0.2277
Plasmodium vivax importin-beta 2, putative 0.0028 0.0105 0.1944
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0028 0.005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0058 0.0289 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.014 0.0784
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0117 0.0655 0.3662
Leishmania major metallo-beta-lactamase family protein-like protein 0.0034 0.014 0.0753
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0163 0.0287
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0289 0.0509
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0787 0.1383
Trypanosoma brucei protein kinase, putative 0.0051 0.0248 0.1047
Echinococcus granulosus dnaJ subfamily B 0.042 0.2545 0.4473
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0105 0.0325
Echinococcus multilocularis ETS transcription factor Elf 2 0.0022 0.0067 0.0067
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0058 0.0289 0.0509
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0028 0.005
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0248 0.1333
Leishmania major cathepsin L-like protease 0.0065 0.0332 0.1782
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0102 0.0102
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0122 0.0688 0.1209
Brugia malayi Cathepsin L-like precursor 0.0017 0.0034 0.0059
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.013 0.013
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0335 0.0589
Leishmania major importin beta-1 subunit, putative 0.0023 0.0071 0.0382
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.0586
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0055 0.031
Echinococcus multilocularis tumor protein p63 0.0343 0.2067 0.2067
Leishmania major DNA damage repair protein, putative 0.0018 0.004 0.0214
Echinococcus granulosus flap endonuclease 1 0.0027 0.0094 0.0165
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0335 0.1484
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0702 0.4303 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Echinococcus granulosus Smad4 0.0025 0.0086 0.0151
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0245 0.1317
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0398 0.0891
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0089 0.0477
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0787 0.1383
Echinococcus granulosus dna polymerase kappa 0.0058 0.0289 0.0509
Loa Loa (eye worm) hypothetical protein 0.0083 0.0443 0.0778
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.013 0.0455
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0034 0.014 0.0753
Trichomonas vaginalis hypothetical protein 0.0107 0.0594 0.332
Trypanosoma brucei unspecified product 0.004 0.0177 0.0691
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0335 0.0589
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0289 0.1556
Entamoeba histolytica protein kinase domain containing protein 0.0013 0.0009 0.005
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0298 0.1788 0.1788
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.186 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0247 0.1469 0.1469
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0022 0.0067 0.0118
Loa Loa (eye worm) hypothetical protein 0.0219 0.1295 0.2277
Brugia malayi ImpB/MucB/SamB family protein 0.0083 0.0443 0.0778
Leishmania major hypothetical protein, conserved 0.0033 0.013 0.07
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0184 0.1073 0.1073
Brugia malayi hypothetical protein 0.0636 0.3893 0.6843
Brugia malayi hypothetical protein 0.049 0.2983 0.5244
Mycobacterium ulcerans hypothetical protein 0.0163 0.0945 0.2124
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.007
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.0034 0.014 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0655 0.3662
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.186 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0842 0.4036
Entamoeba histolytica hypothetical protein 0.0037 0.0156 0.0874
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0132 0.0751 0.132
Schistosoma mansoni ferritin 0.0027 0.0094 0.0331
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0398 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0236 0.0236
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0058 0.0289 0.0289
Leishmania major mitochondrial DNA polymerase beta 0.031 0.186 1
Toxoplasma gondii hypothetical protein 0.005 0.0239 0.2133
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0332 0.1782
Schistosoma mansoni hypothetical protein 0.042 0.2545 0.8924
Schistosoma mansoni hypothetical protein 0.0184 0.1073 0.3762
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0193 0.1039
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0247 0.1469 0.2581
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0219 0.1295 0.2277
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Entamoeba histolytica metallo-beta-lactamase family protein 0.0034 0.014 0.0784
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0246 0.0433
Mycobacterium ulcerans hydrolase 0.0034 0.014 0.0235
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0582 0.3556 0.8248
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0398 0.1397
Mycobacterium tuberculosis Beta lactamase like protein 0.0034 0.014 0.0109
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0117 0.0655 0.2297
Entamoeba histolytica hypothetical protein 0.0184 0.1073 0.5998
Echinococcus multilocularis cysteine protease 0.0017 0.0034 0.0034
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.0193 0.1656
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Onchocerca volvulus Huntingtin homolog 0.0136 0.0773 0.1985
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.014 0.0784
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Loa Loa (eye worm) hypothetical protein 0.0136 0.0773 0.1359
Loa Loa (eye worm) nuclear factor I 0.0014 0.0015 0.0027
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0184 0.1073 0.1885
Schistosoma mansoni hypothetical protein 0.0303 0.1817 0.6372
Brugia malayi MH1 domain containing protein 0.0014 0.0015 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.004 0.0214
Trichomonas vaginalis DNA polymerase eta, putative 0.0058 0.0289 0.1619
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0398 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0199 0.1071
Echinococcus granulosus cpg binding protein 0.0096 0.0525 0.0922
Brugia malayi MH1 domain containing protein 0.0025 0.0086 0.0151
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0398 0.0841
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0028 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0055 0.031
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0246 0.0433
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0842 0.4527
Echinococcus granulosus ETS transcription factor Elf 2 0.0022 0.0067 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Schistosoma mansoni DNA polymerase eta 0.0083 0.0443 0.1553
Entamoeba histolytica hypothetical protein 0.0184 0.1073 0.5998
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0162 0.0162
Trichomonas vaginalis helicase, putative 0.0021 0.0055 0.031
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0034 0.018
Brugia malayi jmjC domain containing protein 0.0122 0.0688 0.1209
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0787 0.276
Leishmania major hypothetical protein, conserved 0.0026 0.0089 0.0477
Loa Loa (eye worm) cysteine protease 0.0017 0.0034 0.0059
Schistosoma mansoni apoferritin-2 0.0027 0.0094 0.0331
Schistosoma mansoni jumonji domain containing protein 0.0033 0.013 0.0457
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.0289 0.1556
Loa Loa (eye worm) hypothetical protein 0.0924 0.5689 1
Trypanosoma brucei hydroxyacylglutathione hydrolase, putative 0.0034 0.014 0.0504
Entamoeba histolytica hypothetical protein 0.0184 0.1073 0.5998
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.014 0.0109
Schistosoma mansoni hypothetical protein 0.0022 0.0067 0.0236
Trichomonas vaginalis beta lactamase domain, putative 0.0034 0.014 0.0784
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0034 0.014 0.014
Brugia malayi MH1 domain containing protein 0.0014 0.0015 0.0027
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0289 0.1256
Brugia malayi Cathepsin L-like precursor 0.0017 0.0034 0.0059
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0582 0.3556 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0117 0.0655 0.0655
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0018 0.004 0.0065
Schistosoma mansoni ferritin light chain 0.0027 0.0094 0.0331
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0028 0.0028
Schistosoma mansoni smad 0.0025 0.0086 0.0301
Schistosoma mansoni ferritin light chain 0.0027 0.0094 0.0331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0298 0.1788 0.3143
Echinococcus multilocularis ubiquitin specific protease 41 0.0117 0.0655 0.0655
Trichomonas vaginalis CAMK family protein kinase 0.0298 0.1788 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0071 0.0397
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.009 0.1541
Echinococcus granulosus dna polymerase eta 0.0083 0.0443 0.0778
Brugia malayi jmjC domain containing protein 0.0033 0.013 0.0229
Trypanosoma brucei DNA polymerase eta, putative 0.0083 0.0443 0.2027
Echinococcus multilocularis ferritin 0.0027 0.0094 0.0094
Entamoeba histolytica alkyl sulfatase, putative 0.0034 0.014 0.0784
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.009 0.1541
Brugia malayi Cathepsin L-like precursor 0.0017 0.0034 0.0059
Mycobacterium leprae POSSIBLE HYDROLASE 0.0034 0.014 0.0145
Trypanosoma cruzi glyoxalase II 0.0034 0.014 0.0753
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0094 0.0146
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Schistosoma mansoni cpg binding protein 0.0096 0.0525 0.184
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0068 0.0119
Echinococcus multilocularis muscleblind protein 0.0924 0.5689 0.5689
Echinococcus granulosus importin subunit beta 1 0.0028 0.0105 0.0184
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0034 0.014 0.0246
Loa Loa (eye worm) hypothetical protein 0.0924 0.5689 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0289 0.1556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0122 0.0688 0.0688
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0034 0.014 0.0753
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0787 0.276
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Brugia malayi serine/threonine-protein kinase plk-2 0.0298 0.1788 0.3143
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.0323
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.014 0.0109
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0022 0.0067 0.0067
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.005
Plasmodium falciparum flap endonuclease 1 0.0027 0.0094 0.166
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0034 0.0188
Brugia malayi Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. 0.0034 0.014 0.0246
Mycobacterium ulcerans lipoprotein LpqF 0.0337 0.2028 0.4663
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0034 0.0086
Plasmodium falciparum cytosolic glyoxalase II 0.0034 0.014 0.292
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0034 0.0118
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0248 0.0248
Echinococcus multilocularis dnaJ subfamily B 0.042 0.2545 0.2545
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0787 0.0787
Trichomonas vaginalis CAMK family protein kinase 0.0298 0.1788 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.013 0.0229
Brugia malayi MH2 domain containing protein 0.0373 0.2252 0.3958
Brugia malayi RNA, U transporter 1 0.0081 0.0431 0.0757
Brugia malayi DNA-binding protein D-ETS-3 0.0022 0.0067 0.0118
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0034 0.0034
Trypanosoma cruzi polo-like protein kinase, putative 0.0298 0.1788 0.9614
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.014 0.0784
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0094 0.0165
Entamoeba histolytica metallo-beta-lactamase family protein 0.0034 0.014 0.0784
Schistosoma mansoni kinase 0.0152 0.0875 0.3067
Onchocerca volvulus 0.005 0.0241 0.0618
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0177 0.0691
Mycobacterium leprae conserved hypothetical protein 0.0034 0.014 0.0145
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0089 0.1514
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Brugia malayi Ets-domain containing protein 0.0022 0.0067 0.0118
Entamoeba histolytica metallo-beta-lactamase superfamily protein 0.0034 0.014 0.0784
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0058 0.0058
Mycobacterium ulcerans beta lactamase-like protein 0.0034 0.014 0.0235
Loa Loa (eye worm) Smad1 0.0025 0.0086 0.0151
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0335 0.0335
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0094 0.0273
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0094 0.0506
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Echinococcus multilocularis survival motor neuron protein 1 0.049 0.2983 0.2983
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Onchocerca volvulus 0.0017 0.0034 0.0086
Schistosoma mansoni hypothetical protein 0.0016 0.0028 0.01
Mycobacterium tuberculosis Conserved protein 0.0034 0.014 0.0109
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0094 0.0526
Brugia malayi hypothetical protein 0.0026 0.0089 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Loa Loa (eye worm) hypothetical protein 0.0117 0.0655 0.1151
Loa Loa (eye worm) MH2 domain-containing protein 0.0373 0.2252 0.3958
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0034 0.018
Echinococcus multilocularis kelch ECH associated protein 1 0.0298 0.1785 0.1785
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0248 0.087
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0248 0.2224
Entamoeba histolytica Ran family GTPase 0.0021 0.0058 0.0323
Entamoeba histolytica protein kinase domain containing protein 0.0013 0.0009 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0055 0.031
Onchocerca volvulus 0.0034 0.014 0.036
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0071 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.013 0.2648
Schistosoma mansoni ets-related 0.0022 0.0067 0.0236
Echinococcus granulosus geminin 0.034 0.2047 0.3598
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Trichomonas vaginalis beta lactamase domain, putative 0.0034 0.014 0.0784
Trypanosoma cruzi polo-like protein kinase, putative 0.0298 0.1788 0.9614
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Entamoeba histolytica hypothetical protein 0.0184 0.1073 0.5998
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.013 0.07
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.0034 0.014 0.0491
Trichomonas vaginalis A-type flavoprotein 0.0034 0.014 0.0784
Echinococcus multilocularis cpg binding protein 0.0096 0.0525 0.0525
Leishmania major cathepsin L-like protease 0.0065 0.0332 0.1782
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Leishmania major cathepsin L-like protease 0.0065 0.0332 0.1782
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0105 0.0736
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0117 0.0655 0.3662
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.0102
Schistosoma mansoni terminal deoxycytidyl transferase 0.0058 0.0289 0.1015
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0398 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0335 0.1174
Trichomonas vaginalis CAMK family protein kinase 0.0298 0.1788 1
Trichomonas vaginalis ferritin, putative 0.0027 0.0094 0.0527
Loa Loa (eye worm) hypothetical protein 0.005 0.0241 0.0423
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0055 0.031
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0058 0.0311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Trypanosoma cruzi DNA polymerase eta, putative 0.0083 0.0443 0.2381
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0241 0.0844
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0089 0.1514
Schistosoma mansoni zinc phosphodiesterase 0.0034 0.014 0.0491
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0058 0.0289 0.1015
Brugia malayi MH2 domain containing protein 0.0025 0.0086 0.0151
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.0945 0.2023
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0086 0.0086
Entamoeba histolytica hypothetical protein 0.0037 0.0156 0.0874
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0086 0.0151
Brugia malayi Cathepsin L-like precursor 0.0017 0.0034 0.0059
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0702 0.4303 1
Mycobacterium ulcerans hydrolase 0.0034 0.014 0.0235
Leishmania major cathepsin L-like protease 0.0017 0.0034 0.018
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0149 0.0858 0.4797
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0117 0.0655 0.1151
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0177 0.0691
Loa Loa (eye worm) hypothetical protein 0.0028 0.0105 0.0184
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0034 0.0059
Echinococcus granulosus kelch ECH associated protein 1 0.0298 0.1785 0.3138
Onchocerca volvulus Serine\/threonine kinase homolog 0.0298 0.1788 0.4593
Leishmania major hypothetical protein, conserved 0.007 0.0365 0.1962
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.014 0.0784
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0055 0.031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0787 0.0787
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0022 0.0067 0.0118
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0034 0.0059
Echinococcus granulosus cathepsin l1 0.0017 0.0034 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0298 0.1788 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Brugia malayi CXXC zinc finger family protein 0.0091 0.0492 0.0865
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0089 0.1514
Echinococcus multilocularis ETHE1 protein 0.0034 0.014 0.014
Leishmania major cathepsin L-like protease 0.0017 0.0034 0.018
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0117 0.0655 0.2297
Schistosoma mansoni tsg101-related 0.0183 0.1067 0.374
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0058 0.0102
Schistosoma mansoni hypothetical protein 0.0034 0.014 0.0491
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.005
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0335 0.0589
Leishmania major cleavage and polyadenylation specificity factor, putative 0.0034 0.014 0.0753
Echinococcus granulosus smad 0.0025 0.0086 0.0151
Loa Loa (eye worm) hypothetical protein 0.0033 0.013 0.0229
Schistosoma mansoni Smad4 0.0025 0.0086 0.0301
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.013 0.013
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0094 0.166
Toxoplasma gondii hypothetical protein 0.0026 0.009 0.0583
Toxoplasma gondii hydroxyacylglutathione hydrolase 0.0034 0.014 0.1105
Brugia malayi Ets-domain containing protein 0.0154 0.0891 0.1565
Giardia lamblia Kinase, PLK 0.0298 0.1788 1
Echinococcus multilocularis muscleblind protein 1 0.0924 0.5689 0.5689
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Echinococcus multilocularis geminin 0.034 0.2047 0.2047
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0248 0.1333
Leishmania major DNA polymerase eta, putative 0.0043 0.0193 0.1039
Entamoeba histolytica deoxycytidyl transferase, putative 0.0058 0.0289 0.1619
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0248 0.0436
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0337 0.2028 0.4594
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.1788 0.6271
Brugia malayi MAP kinase sur-1 0.0051 0.0248 0.0436
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Plasmodium vivax hydroxyacyl glutathione hydrolase, putative 0.0034 0.014 0.292
Loa Loa (eye worm) hypothetical protein 0.0636 0.3893 0.6843
Trichomonas vaginalis CAMK family protein kinase 0.0298 0.1788 1
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Leishmania major GTP-binding protein, putative 0.0021 0.0058 0.0311
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0094 0.0128
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0028 0.0028
Schistosoma mansoni ferritin 0.0027 0.0094 0.0331
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0117 0.0655 0.3521
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.013 0.0229
Plasmodium vivax JmjC domain containing protein 0.0033 0.013 0.2648
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.014 0.0109
Entamoeba histolytica hypothetical protein 0.0037 0.0156 0.0874
Echinococcus multilocularis phd:f box containing protein 0.0033 0.013 0.013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0034 0.0059
Echinococcus granulosus GA binding protein alpha chain 0.0154 0.0891 0.1565
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Leishmania major hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative 0.0034 0.014 0.0753
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.013 0.0229
Mycobacterium leprae Beta-lactamase-like protein 0.0034 0.014 0.0145
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.0664
Loa Loa (eye worm) hypothetical protein 0.0016 0.0028 0.005
Echinococcus granulosus ETS transcription factor Elf 1 0.0022 0.0067 0.0118
Schistosoma mansoni smad1 5 8 and 0.0025 0.0086 0.0301
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0332 0.1782
Echinococcus multilocularis ewsr:fli fusion protein type 0.0022 0.0067 0.0067
Schistosoma mansoni cpg binding protein 0.0096 0.0525 0.184
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0332 0.1782
Echinococcus granulosus kelch ECH associated protein 1 like 0.0298 0.1785 0.3138
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0086 0.0151
Schistosoma mansoni jumonji domain containing protein 0.0122 0.0688 0.2411
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.072 0.2524
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0034 0.014 0.0784
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.007 0.0365 0.1962
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.004 0.0065
Brugia malayi Importin beta-1 subunit 0.0028 0.0105 0.0184
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0117 0.0655 0.3094
Loa Loa (eye worm) fibroinase 0.0017 0.0034 0.0059
Giardia lamblia DINP protein human, muc B family 0.0058 0.0289 0.1619
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Brugia malayi transcription factor E74 isoform 0.0022 0.0067 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0013 0.0009 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0259 0.1391
Echinococcus multilocularis lysine specific demethylase 5A 0.0122 0.0688 0.0688
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0094 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.085 0.4754
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0156 0.0874
Trichomonas vaginalis ran, putative 0.0021 0.0058 0.0323
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0335 0.18
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.0102
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0248 0.1047
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0842 0.4527
Echinococcus granulosus expressed protein 0.0027 0.0094 0.0166
Echinococcus multilocularis protein C ets 2 0.0022 0.0067 0.0067
Mycobacterium ulcerans Zn-dependent glyoxylase 0.0034 0.014 0.0235
Schistosoma mansoni importin beta-1 0.0028 0.0105 0.0366
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0117 0.0655 0.3521
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0199 0.1071
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0094 0.0628
Brugia malayi hypothetical protein 0.0184 0.1073 0.1885
Plasmodium falciparum DNA repair protein REV1, putative 0.0018 0.004 0.0172
Echinococcus multilocularis Smad4 0.0025 0.0086 0.0086
Mycobacterium ulcerans hypothetical protein 0.0034 0.014 0.0235
Schistosoma mansoni hypothetical protein 0.0016 0.0028 0.01
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.1817 0.3194
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0248 0.0436
Leishmania major cathepsin L-like protease 0.0017 0.0034 0.018
Schistosoma mansoni hypothetical protein 0.0034 0.014 0.0491
Schistosoma mansoni hypothetical protein 0.0016 0.0028 0.01
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.013 0.0457
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0289 0.0586
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0102 0.018
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.013 0.0229
Echinococcus multilocularis ETS transcription factor Elf 2 0.0022 0.0067 0.0067
Echinococcus granulosus ETHE1 protein 0.0034 0.014 0.0246
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0013 0.0009 0.005
Brugia malayi Flap endonuclease-1 0.0027 0.0094 0.0165
Brugia malayi Probable ClpP-like protease 0.0076 0.0398 0.07
Echinococcus multilocularis smad 0.0025 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0014 0.0015 0.0027
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0154 0.0891 0.1565
Echinococcus multilocularis dna polymerase kappa 0.0058 0.0289 0.0289
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0335 0.1872
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0289 0.1256
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0055 0.031
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0034 0.0034
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0398 1
Schistosoma mansoni zinc phosphodiesterase 0.0034 0.014 0.0491
Leishmania major DNA polymerase eta, putative 0.0083 0.0443 0.2381
Schistosoma mansoni ets-related 0.0469 0.2852 1
Schistosoma mansoni protein phosphatase 2C 0.0033 0.013 0.0457
Trichomonas vaginalis beta lactamase domain, putative 0.0034 0.014 0.0784
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0117 0.0655 0.3521
Trypanosoma brucei polo-like protein kinase 0.0298 0.1788 0.8796
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.013 0.1002
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0289 0.1256
Loa Loa (eye worm) hypothetical protein 0.0034 0.014 0.0246
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Giardia lamblia DNA damage repair protein 0.0018 0.004 0.0223
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.0034 0.014 0.0246
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0086 0.0086
Echinococcus multilocularis GA binding protein alpha chain 0.0154 0.0891 0.0891
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0398 0.3785
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Brugia malayi ethe1-prov protein 0.0034 0.014 0.0246
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0094 0.0013
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Onchocerca volvulus 0.0017 0.0034 0.0086
Trypanosoma cruzi glyoxalase II 0.0034 0.014 0.0753
Trypanosoma cruzi metallo-beta-lactamase superfamily, putative 0.0034 0.014 0.0753
Loa Loa (eye worm) hypothetical protein 0.0033 0.013 0.0229
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0094 0.0526
Brugia malayi Fli-1 protein 0.0469 0.2852 0.5012
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.0034 0.014 0.0246
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0398 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0398 0.07
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0156 0.084
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0034 0.0086
Loa Loa (eye worm) D-ets-2 protein 0.0022 0.0067 0.0118
Echinococcus granulosus lysine specific demethylase 5A 0.0127 0.072 0.1265
Brugia malayi hypothetical protein 0.0136 0.0773 0.1359
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.0289 0.0464
Schistosoma mansoni tsg101-related 0.0149 0.0858 0.3009
Echinococcus granulosus ETS transcription factor Elf 5 0.0022 0.0067 0.0118
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0337 0.2028 0.5591
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Brugia malayi Cathepsin L-like precursor 0.0017 0.0034 0.0059
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0219 0.1295 0.1295
Loa Loa (eye worm) hypothetical protein 0.0034 0.014 0.0246
Brugia malayi jmjC domain containing protein 0.0127 0.072 0.1265
Trypanosoma brucei beta lactamase 0.0337 0.2028 1
Trichomonas vaginalis CAMK family protein kinase 0.0298 0.1788 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.013 0.1002
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0248 0.0436
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Leishmania major DNA polymerase kappa, putative 0.0018 0.004 0.0214
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0068 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Echinococcus multilocularis kelch ECH associated protein 1 0.0298 0.1785 0.1785
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Brugia malayi jmjC domain containing protein 0.0033 0.013 0.0229
Loa Loa (eye worm) hypothetical protein 0.0034 0.014 0.0246
Schistosoma mansoni hypothetical protein 0.0034 0.014 0.0491
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0034 0.0059
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0236 0.0337
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0236 0.0337
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0289 0.0586
Schistosoma mansoni transcription factor LCR-F1 0.0184 0.1073 0.3762
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0199 0.1071
Echinococcus granulosus phd:f box containing protein 0.0033 0.013 0.0229
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Echinococcus granulosus ewsr:fli fusion protein type 0.0022 0.0067 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.014 0.0784
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0228 0.0402
Echinococcus multilocularis expressed protein 0.0027 0.0094 0.0094
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.013 0.0229
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0398 0.0398
Trypanosoma brucei cleavage and polyadenylation specificity factor subunit, putative 0.0034 0.014 0.0504
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0156 0.0874
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0289 0.1556
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Onchocerca volvulus 0.0091 0.0492 0.1265
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.013 0.0229
Mycobacterium tuberculosis Possible hydrolase 0.0034 0.014 0.0109
Echinococcus granulosus ETS transcription factor Elf 2 0.0022 0.0067 0.0118
Mycobacterium tuberculosis Conserved protein 0.0034 0.014 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Trypanosoma cruzi hydroxyacylglutathione hydrolase, putative 0.0034 0.014 0.0753
Echinococcus multilocularis zinc phosphodiesterase 0.0034 0.014 0.014
Trypanosoma brucei metallo-beta-lactamase-like protein, putative 0.0034 0.014 0.0504
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0248 0.1387
Trypanosoma brucei Vps23 core domain containing protein, putative 0.007 0.0365 0.1635
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0398 0.3785
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0068 0.0238
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0034 0.014 0.0246
Loa Loa (eye worm) hypothetical protein 0.0136 0.0773 0.1359
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0248 0.1387
Brugia malayi metallo-beta-lactamase superfamily protein 0.0034 0.014 0.0246
Schistosoma mansoni hypothetical protein 0.0022 0.0067 0.0236
Schistosoma mansoni ets 0.0022 0.0067 0.0236
Schistosoma mansoni hypothetical protein 0.0035 0.0146 0.051
Toxoplasma gondii metallo-beta-lactamase domain-containing protein 0.0034 0.014 0.1105
Schistosoma mansoni hypothetical protein 0.034 0.2047 0.7179
Entamoeba histolytica tyrosine kinase, putative 0.0013 0.0009 0.005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0091 0.0492 0.0865
Schistosoma mansoni cpg binding protein 0.0091 0.0492 0.1727
Entamoeba histolytica cysteine protease, putative 0.0017 0.0034 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.013 0.07
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0177 0.0691
Schistosoma mansoni elf1 0.0022 0.0067 0.0236
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.004 0.0214
Brugia malayi metallo-beta-lactamase superfamily protein 0.0034 0.014 0.0246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Leishmania major DNA polymerase kappa, putative 0.0058 0.0289 0.1556
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Mycobacterium tuberculosis Conserved protein 0.0034 0.014 0.0109
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0034 0.0059
Schistosoma mansoni gabp alpha 0.0154 0.0891 0.3123
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0058 0.0251
Giardia lamblia Hydroxyacylglutathione hydrolase 0.0034 0.014 0.0784
Brugia malayi polk-prov protein 0.0018 0.004 0.007
Trichomonas vaginalis apoptosis inducing factor, putative 0.0034 0.014 0.0784
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0034 0.0118
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0037 0.0156 0.084
Entamoeba histolytica metallo-beta-lactamase family protein 0.0034 0.014 0.0784
Giardia lamblia Metallo-beta-lactamase superfamily protein 0.0034 0.014 0.0784
Echinococcus granulosus GPCR family 2 0.0016 0.0028 0.005
Echinococcus multilocularis dna polymerase eta 0.0083 0.0443 0.0443
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0022 0.0067 0.0118
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0236 0.0423
Brugia malayi MH2 domain containing protein 0.0025 0.0086 0.0151
Onchocerca volvulus 0.01 0.0551 0.1415
Onchocerca volvulus Putative hydrolase PNKD 0.0034 0.014 0.036
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0058 0.0311
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Echinococcus granulosus tumor protein p63 0.0343 0.2067 0.3634
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Brugia malayi Ets-domain containing protein 0.0154 0.0891 0.1565
Mycobacterium leprae conserved hypothetical protein 0.0034 0.014 0.0145
Echinococcus multilocularis GPCR, family 2 0.0016 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0035 0.0146 0.0256
Onchocerca volvulus Hydroxyacylglutathione hydrolase, mitochondrial homolog 0.0034 0.014 0.036
Onchocerca volvulus 0.0017 0.0034 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0034 0.0188
Loa Loa (eye worm) jmjC domain-containing protein 0.0127 0.072 0.1265
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0034 0.0188
Mycobacterium ulcerans hydrolase 0.0034 0.014 0.0235
Trichomonas vaginalis beta lactamase domain, putative 0.0034 0.014 0.0784
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0199 0.0802
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0058 0.0289 0.1619
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0022 0.0067 0.0236
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0094 0.0506
Wolbachia endosymbiont of Brugia malayi metallo-beta-lactamase superfamily hydrolase 0.0034 0.014 0.1507
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0086 0.0151
Trypanosoma brucei glyoxalase II 0.0034 0.014 0.0504
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0146 0.0256
Treponema pallidum ribonuclease Z 0.0034 0.014 0.1631
Echinococcus granulosus ubiquitin specific protease 41 0.0117 0.0655 0.1151
Loa Loa (eye worm) hypothetical protein 0.0022 0.0067 0.0118
Onchocerca volvulus 0.0636 0.3893 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0034 0.0188
Trypanosoma cruzi metallo-beta-lactamase-like protein, putative 0.0034 0.014 0.0753
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0016 0.0028 0.01
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0248 0.1333
Trypanosoma cruzi DNA damage repair protein, putative 0.0018 0.004 0.0214
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0551 0.0968
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0071 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0787 0.276
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0068 0.0068
Schistosoma mansoni ferritin 0.0027 0.0094 0.0331
Schistosoma mansoni ran 0.0021 0.0058 0.0203
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0117 0.0655 0.1151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0332 0.1467
Brugia malayi jmjC domain containing protein 0.0033 0.013 0.0229
Echinococcus multilocularis cysteine protease 0.0017 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Echinococcus granulosus protein C ets 2 0.0022 0.0067 0.0118
Loa Loa (eye worm) fli-1 protein 0.0469 0.2852 0.5012
Mycobacterium ulcerans hypothetical protein 0.0034 0.014 0.0235
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.186 0.9157
Trypanosoma brucei unspecified product 0.004 0.0177 0.0691
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0086 0.0301
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0058 0.009
Leishmania major cathepsin L-like protease 0.0017 0.0034 0.018
Mycobacterium ulcerans hypothetical protein 0.0034 0.014 0.0235
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0398 0.07
Schistosoma mansoni hypothetical protein 0.01 0.0551 0.1932
Entamoeba histolytica protein kinase domain containing protein 0.0013 0.0009 0.005
Leishmania major metallo-beta-lactamase family-like protein 0.0034 0.014 0.0753
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0163 0.0163
Schistosoma mansoni DNA polymerase IV / kappa 0.0018 0.004 0.014
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.0289 0.0464
Schistosoma mansoni survival motor neuron protein 0.01 0.0551 0.1932
Entamoeba histolytica protein kinase domain containing protein 0.0013 0.0009 0.005
Schistosoma mansoni apoferritin-2 0.0027 0.0094 0.0331
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0034 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.004 0.0214
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0192 0.1126 0.3948
Trichomonas vaginalis CAMK family protein kinase 0.0298 0.1788 1
Schistosoma mansoni phd/f-box containing protein 0.0033 0.013 0.0457
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0071 0.0382
Echinococcus granulosus zinc phosphodiesterase 0.0034 0.014 0.0246
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0117 0.0655 0.1151
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0289 0.1256
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0246 0.0433
Leishmania major cathepsin L-like protease 0.0017 0.0034 0.018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0009 0.003
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.0373 0.2252 0.3958
Mycobacterium ulcerans glyoxalase II, GloB 0.0034 0.014 0.0235
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.013 0.0457
Brugia malayi hypothetical protein 0.0017 0.0032 0.0056
Loa Loa (eye worm) hypothetical protein 0.0026 0.0089 0.0156
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0117 0.0655 0.0655
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0162 0.0285
Echinococcus granulosus snurportin 1 0.0303 0.1817 0.3194
Loa Loa (eye worm) hypothetical protein 0.0033 0.013 0.0229
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0298 0.1788 0.9614
Loa Loa (eye worm) hypothetical protein 0.0051 0.0246 0.0433
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0117 0.0655 0.3662
Echinococcus granulosus ETS domain containing protein Elk 1 0.0022 0.0067 0.0118
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0117 0.0655 0.3662
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.0034 0.014 0.014
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0248 0.1387
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0055 0.031
Onchocerca volvulus 0.0017 0.0034 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.014 0.0784
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0298 0.1788 0.3143
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0335 0.18
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0034 0.0188
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0248 0.1333

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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