Detailed information for compound 794342

Basic information

Technical information
  • TDR Targets ID: 794342
  • Name: 3,5-bis(4-methoxyphenyl)-2-phenyl-3a,6a-dihyd ro-3H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione
  • MW: 430.453 | Formula: C25H22N2O5
  • H donors: 0 H acceptors: 2 LogP: 3.98 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C1C2C(=O)N(C(=O)C2ON1c1ccccc1)c1ccc(cc1)OC
  • InChi: 1S/C25H22N2O5/c1-30-19-12-8-16(9-13-19)22-21-23(32-27(22)18-6-4-3-5-7-18)25(29)26(24(21)28)17-10-14-20(31-2)15-11-17/h3-15,21-23H,1-2H3
  • InChiKey: KJVGAKSWUZWNON-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3,5-bis(4-methoxyphenyl)-2-phenyl-3a,6a-dihydro-3H-pyrrolo[3,4-d]isoxazole-4,6-dione
  • 3,5-bis(4-methoxyphenyl)-2-phenyl-3a,6a-dihydro-3H-pyrrolo[3,4-d]isoxazole-4,6-quinone
  • A2908/0122562
  • EU-0053539

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0014 0.0014
Echinococcus granulosus sex peptide receptor 0.0032 0.0014 0.0014
Plasmodium vivax transporter, putative 0.0014 0.0002 0.0525
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0059 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0014 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Trypanosoma cruzi transporter, putative 0.0014 0.0002 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni histamine h1 receptor 0.0032 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Onchocerca volvulus 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Leishmania major integral membrane transport protein, putative,drug resistence protein, putative 0.0014 0.0002 0.0002
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus granulosus neuropeptide receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.0014 0.0014
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0059 0.0059
Schistosoma mansoni oxalate:formate antiporter 0.0014 0.0002 0.0002
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.0014 0.0014
Onchocerca volvulus Putative transporter 0.0014 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor 0.0032 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 1.4865 1 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0146 0.0091 0.5095
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus sugar phosphate exchanger 3 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0188 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.0032 0.0014 0.0014
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0014 0.0002 0.009
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0014 0.0014
Trypanosoma cruzi drug resistance protein, putative 0.0014 0.0002 0.0001
Trypanosoma brucei riboflavin transporter 0.0014 0.0002 0.0002
Entamoeba histolytica major facilitator superfamily protein 0.0014 0.0002 0.0685
Schistosoma mansoni hypothetical protein 0.0387 0.0253 0.0253
Echinococcus multilocularis survival motor neuron protein 1 0.0252 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0003 0.0896
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.034 0.0222 0.0222
Toxoplasma gondii hypothetical protein 0.0028 0.0012 0.3617
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0014 0.0014
Brugia malayi Calcitonin receptor-like protein seb-1 0.0108 0.0065 0.0065
Echinococcus granulosus GPCR family 2 0.0034 0.0015 0.0015
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0006 0.0268
Trichomonas vaginalis ran, putative 0.0043 0.0022 0.116
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Echinococcus granulosus somatostatin receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0517 0.034 0.034
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Echinococcus granulosus vesicular glutamate transporter 0.0014 0.0002 0.0002
Brugia malayi transporter 0.0014 0.0002 0.0002
Plasmodium vivax monocarboxylate transporter, putative 0.0014 0.0002 0.0525
Schistosoma mansoni tetracycline-efflux transporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0167 0.0105 0.0105
Plasmodium falciparum thioredoxin reductase 0.002 0.0006 0.1849
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Trypanosoma brucei protein associated with differentiation 5, putative 0.0014 0.0002 0.0002
Plasmodium vivax transporter, putative 0.0014 0.0002 0.0525
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein 0.0014 0.0002 0.0001
Schistosoma mansoni oxalate:formate antiporter 0.0014 0.0002 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0006 0.0006
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0006 0.1849
Schistosoma mansoni sugar transporter 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0006 0.0007
Schistosoma mansoni hypothetical protein 0.0034 0.0015 0.0015
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0006 0.0006
Brugia malayi ORL1-like opioid receptor 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Toxoplasma gondii zinc finger protein 36 family 3 protein 0.0014 0.0002 0.0525
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Schistosoma mansoni transport proetin (smap-4-related) 0.0014 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Schistosoma mansoni importin beta-1 0.0059 0.0032 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.0012
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Probable reductase 0.0131 0.0081 0.4531
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0014 0.0014
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Brugia malayi Thioredoxin reductase 0.0058 0.0031 0.0031
Onchocerca volvulus 0.0032 0.0014 0.0014
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0006 0.0342
Onchocerca volvulus 0.0028 0.0012 0.0011
Schistosoma mansoni drug transporter 0.0014 0.0002 0.0002
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.0014 0.0014
Echinococcus multilocularis GPCR, family 2 0.0034 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0014 0.0002 0.009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus multilocularis vesicular acetylcholine transporter 1.4865 1 1
Onchocerca volvulus 0.0014 0.0002 0.0001
Echinococcus granulosus sodium dependent phosphate transport protein 1 0.0014 0.0002 0.0002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0006 0.0248
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Schistosoma mansoni DNA polymerase eta 0.0021 0.0006 0.0006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0278 0.018 0.018
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0146 0.0091 0.5095
Brugia malayi Dopamine receptor protein 1 0.0032 0.0014 0.0014
Echinococcus multilocularis sex peptide receptor 0.0032 0.0014 0.0014
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0058 0.0031 0.1691
Echinococcus granulosus hypothetical protein 0.0032 0.0014 0.0014
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Trypanosoma cruzi integral membrane transport protein, putative 0.0014 0.0002 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0014 0.0014
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi Dopamine receptor protein 2 0.0032 0.0014 0.0014
Echinococcus granulosus Hippocampus abundant transcript 1 protein 0.0014 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0074 0.0042 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0006
Onchocerca volvulus 0.0032 0.0014 0.0014
Echinococcus multilocularis solute carrier family 43 0.0014 0.0002 0.0002
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0014 0.0002 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Echinococcus multilocularis monocarboxylate transporter 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Echinococcus multilocularis orexin receptor type 2 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Onchocerca volvulus 0.0014 0.0002 0.0001
Trypanosoma brucei unspecified product 0.0014 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0612 0.0404 0.0404
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0022 0.6744
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.0014 0.0014
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0014 0.0002 0.0002
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Echinococcus granulosus allatostatin A receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0006
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis thioredoxin glutathione reductase 0.0058 0.0031 0.0031
Brugia malayi putative neuropeptide receptor 0.0032 0.0014 0.0014
Schistosoma mansoni biogenic amine receptor 0.0032 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0387 0.0253 0.0253
Onchocerca volvulus 0.0032 0.0014 0.0014
Onchocerca volvulus EG:103B4.3 protein homolog 0.0014 0.0002 0.0001
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.0002
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Brugia malayi RNA, U transporter 1 0.0167 0.0105 0.0105
Echinococcus multilocularis sugar phosphate exchanger solute carrier family 0.0014 0.0002 0.0002
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.0014 0.0014
Entamoeba histolytica sucrose transporter, putative 0.0014 0.0002 0.0685
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni transporter spinster-related 0.0014 0.0002 0.0002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0253 0.0163 0.0163
Trypanosoma brucei protein associated with differentiation 7, putative 0.0014 0.0002 0.0002
Brugia malayi Pre-SET motif family protein 0.0253 0.0163 0.0163
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0001 0.0038
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0022 0.0022
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis monocarboxylate transporter 0.0014 0.0002 0.0002
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0028 0.0012 0.3617
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0006 0.0006
Schistosoma mansoni oxalate:formate antiporter 0.0014 0.0002 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Brugia malayi Serotonin receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.0014 0.0014
Schistosoma mansoni neuropeptide receptor 0.0032 0.0014 0.0014
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Echinococcus multilocularis somatostatin receptor 0.0032 0.0014 0.0014
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Schistosoma mansoni neuropeptide receptor 0.0032 0.0014 0.0014
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Plasmodium vivax transporter, putative 0.0014 0.0002 0.0525
Trypanosoma brucei protein associated with differentiation 3, putative 0.0014 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Plasmodium falciparum amino acid transporter, putative 0.0028 0.0012 0.3617
Leishmania major DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Schistosoma mansoni sodium/chloride dependent transporter 0.0028 0.0012 0.0012
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.0014 0.0014
Trypanosoma brucei transporter protein, putative 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0034 0.0015 0.0015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0006 0.0007
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0108 0.0065 0.0065
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0006 0.0243
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0032 0.0014 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0015 0.0015
Plasmodium vivax transporter, putative 0.0014 0.0002 0.0525
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.0014 0.0014
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0006 0.1849
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0022 0.0022
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0008 0.042
Schistosoma mansoni ran 0.0043 0.0022 0.0022
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0014 0.0002 0.0002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.0014 0.0014
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0034 0.0015 0.0015
Leishmania major importin beta-1 subunit, putative 0.0048 0.0025 0.0028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0167 0.0105 0.0105
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0014 0.0002 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni phosphate transporter 0.0014 0.0002 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0006 0.0323
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0025 0.1319
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Leishmania major trypanothione reductase 0.0058 0.0031 0.0036
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0006 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Loa Loa (eye worm) hippocampus abundant transcript 1a 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0028 0.0012 0.0011
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0006 0.0007
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0006 0.0006
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0014 0.0002 0.0002
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0015 0.0015
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0014 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0059 0.0059
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0032 0.0032
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0006
Echinococcus granulosus tm gpcr rhodopsin 0.0517 0.034 0.034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0006
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0146 0.0091 1
Onchocerca volvulus 0.0032 0.0014 0.0014
Plasmodium vivax glutathione reductase, putative 0.0058 0.0031 0.9735
Plasmodium vivax SET domain protein, putative 0.0036 0.0017 0.5286
Onchocerca volvulus 0.0036 0.0017 0.0017
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0006 0.0006
Echinococcus granulosus Solute carrier family 22 5 0.0014 0.0002 0.0002
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0002 0.0525
Trypanosoma cruzi transporter, putative 0.0014 0.0002 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Brugia malayi Hypothetical transporter C09D4.1 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0014 0.0002 0.0001
Echinococcus granulosus snurportin 1 0.0628 0.0415 0.0415
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Onchocerca volvulus Sugar phosphate exchanger 3 homolog 0.0014 0.0002 0.0001
Echinococcus granulosus sodium and chloride dependent glycine 0.0028 0.0012 0.0012
Echinococcus granulosus vesicular acetylcholine transporter 1.4865 1 1
Trypanosoma brucei major facilitator superfamily protein (MFS), putative 0.0014 0.0002 0.0002
Trypanosoma brucei Protein Associated with Differentiation, putative 0.0014 0.0002 0.0002
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0014 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0059 0.0059
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0006 0.0007
Brugia malayi hypothetical protein 0.0252 0.0162 0.0162
Trypanosoma brucei transporter, putative 0.0014 0.0002 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0028 0.0012 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0006 0.1849
Leishmania major transporter-like protein 0.0014 0.0002 0.0002
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0006 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0048 0.0025 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0006
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Echinococcus granulosus g protein coupled receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Onchocerca volvulus Phospholipase A2 homolog 0.0188 0.0119 0.0119
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.0014 0.0014
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0002 0.0525
Entamoeba histolytica major facilitator superfamily protein 0.0014 0.0002 0.0685
Brugia malayi Serotonin receptor 0.0032 0.0014 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Brugia malayi hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0015 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0006 0.0006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0022 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0012 0.3617
Schistosoma mansoni amine GPCR 0.0032 0.0014 0.0014
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0006 0.0006
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0001 0.0285
Schistosoma mansoni survival motor neuron protein 0.0051 0.0027 0.0027
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0006 0.1876
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.0014 0.0014
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) RecQ helicase 0.0023 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Toxoplasma gondii thioredoxin reductase 0.0058 0.0031 0.9735
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0014 0.0014
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0002 0.0002
Plasmodium falciparum glutathione reductase 0.002 0.0006 0.1849
Schistosoma mansoni vesicular amine transporter 0.0014 0.0002 0.0002
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.0014 0.0014
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0051 0.0027 0.0027
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0014 0.0014
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0014 0.0002 0.0002
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0017 0.0017
Leishmania major monocarboxylate transporter-like protein 0.0014 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Loa Loa (eye worm) serotonin transporter b 0.0167 0.0105 0.0105
Echinococcus multilocularis monocarboxylate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni drug efflux protein-related 0.0014 0.0002 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0006 0.0007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0002 0.009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0014 0.0014
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0006 0.0248
Trypanosoma brucei protein associated with differentiation 6, putative 0.0014 0.0002 0.0002
Schistosoma mansoni opsin-like receptor 0.0032 0.0014 0.0014
Plasmodium vivax pantothenate transporter, putative 0.0014 0.0002 0.0525
Brugia malayi Melatonin receptor type 1A 0.0032 0.0014 0.0014
Brugia malayi neuropeptide F receptor 0.0032 0.0014 0.0014
Brugia malayi sulfakinin receptor protein 0.0032 0.0014 0.0014
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0017 0.0017
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0002 0.0525
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0006 0.2172
Giardia lamblia DINP protein human, muc B family 0.0021 0.0006 0.2348
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trichomonas vaginalis hypothetical protein 0.0014 0.0002 0.009
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.0014 0.0014
Brugia malayi G-protein coupled receptor 0.0032 0.0014 0.0014
Schistosoma mansoni amine GPCR 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0028 0.0012 0.0011
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0014 0.0002 0.009
Schistosoma mansoni adenoreceptor 0.0032 0.0014 0.0014
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0131 0.0081 0.8893
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus multilocularis solute carrier family 43 0.0014 0.0002 0.0002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Trypanosoma brucei protein associated with differentiation 8, putative 0.0014 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0014 0.0002 0.0685
Echinococcus granulosus dna polymerase kappa 0.0021 0.0006 0.0006
Schistosoma mansoni biogenic amine receptor 0.0032 0.0014 0.0014
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0006 0.0318
Onchocerca volvulus 0.0051 0.0027 0.0027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0059 0.0059
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0014 0.0014
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trypanosoma brucei Protein Associated with Differentiation 1 0.0014 0.0002 0.0002
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Plasmodium falciparum monocarboxylate transporter, putative 0.0014 0.0002 0.0525
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Trypanosoma cruzi transporter, putative 0.0014 0.0002 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0014 0.0014
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0028 0.0012 0.0012
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0028 0.0012 0.0012
Plasmodium falciparum metabolite/drug transporter, putative 0.0014 0.0002 0.0525
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni amine GPCR 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0014 0.0002 0.0001
Onchocerca volvulus Sialin homolog 0.0014 0.0002 0.0001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.0014 0.0014
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0014 0.0002 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0006 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0014 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0006
Echinococcus granulosus solute carrier family 43 0.0014 0.0002 0.0002
Echinococcus multilocularis sodium dependent phosphate transport protein 1 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus multilocularis vesicular glutamate transporter 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.0014 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0014 0.0014
Schistosoma mansoni oxalate:formate antiporter 0.0014 0.0002 0.0002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0006 0.0243
Onchocerca volvulus 0.0014 0.0002 0.0001
Schistosoma mansoni drug efflux protein-related 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0014 0.0002 0.0001
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0014 0.0014
Onchocerca volvulus 0.034 0.0222 0.0221
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0628 0.0415 0.0415
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0028 0.0012 0.0012
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0006 0.1849
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0006 0.4282
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.0014 0.0014
Schistosoma mansoni protein transport protein Sec13 0.0014 0.0002 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0059 0.0059
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Echinococcus granulosus sugar phosphate exchanger 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0014 0.0002 0.0001
Onchocerca volvulus 0.0032 0.0014 0.0014
Trypanosoma brucei C-8 sterol isomerase, putative 1.3016 0.8755 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Loa Loa (eye worm) thioredoxin reductase 0.0058 0.0031 0.0031
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0002 0.0002
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.0014 0.0014
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0006 0.0243
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0252 0.0162 0.0162
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0014 0.0014
Trypanosoma cruzi major facilitator superfamily, putative 0.0014 0.0002 0.0001
Brugia malayi Dopamine receptor 0.0032 0.0014 0.0014
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.0014 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0273 0.0176 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi neuropeptide F receptor 0.0032 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0002 0.0002
Echinococcus granulosus neuropeptide s receptor 0.0032 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Echinococcus multilocularis geminin 0.0387 0.0253 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0017 0.0017
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Brugia malayi hypothetical protein 0.0014 0.0002 0.0002
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0156 0.0098 0.0111
Trypanosoma cruzi phospholipase A1, putative 0.034 0.0222 0.0252
Onchocerca volvulus 0.0014 0.0002 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0006 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0014 0.0014
Trypanosoma cruzi MFS transporter, putative 0.0014 0.0002 0.0001
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0014 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0006 0.9805
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Echinococcus multilocularis feline leukemia virus subgroup C 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis serotonin transporter 0.0167 0.0105 0.0105
Echinococcus multilocularis serotonin receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0014 0.0014
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0002 0.0525
Onchocerca volvulus 0.0032 0.0014 0.0014
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Treponema pallidum sodium- and chloride- dependent transporter 0.0167 0.0105 1
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Echinococcus multilocularis allatostatin A receptor 0.0032 0.0014 0.0014
Trypanosoma brucei unspecified product 0.0021 0.0006 0.0007
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0131 0.0081 0.4531
Toxoplasma gondii exonuclease III APE 0.002 0.0006 0.1876
Brugia malayi transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.0014 0.0014
Plasmodium vivax importin-beta 2, putative 0.0059 0.0032 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.0014 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.0012
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus vesicular glutamate transporter 0.0014 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0014 0.0014
Brugia malayi RE15519p 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Schistosoma mansoni vesicular acetylcholine transporter 1.4865 1 1
Plasmodium falciparum transporter, putative 0.0028 0.0012 0.3617
Echinococcus granulosus solute carrier family 43 0.0014 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0014 0.0002 0.0001
Onchocerca volvulus 0.0032 0.0014 0.0014
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Schistosoma mansoni ran 0.0043 0.0022 0.0022
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.0014 0.0014
Plasmodium falciparum monocarboxylate transporter, putative 0.0014 0.0002 0.0525
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0006 0.2446
Trichomonas vaginalis glucose-6-phosphate translocase, putative 0.0014 0.0002 0.009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0025 0.1319
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Plasmodium vivax amine transporter, putative 0.0028 0.0012 0.3617
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Echinococcus granulosus g-protein coupled receptor 0.0032 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Schistosoma mansoni vesicular amine transporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Onchocerca volvulus 0.0014 0.0002 0.0001
Leishmania major hypothetical protein, conserved in leishmania 0.0014 0.0002 0.0002
Echinococcus multilocularis dna polymerase eta 0.0021 0.0006 0.0006
Brugia malayi larval opioid receptor 0.0032 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0014 0.0002 0.0001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0032 0.0014 0.0014
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0028 0.0012 0.0012
Plasmodium falciparum glutathione reductase 0.0058 0.0031 0.9735
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0014 0.0002 0.009
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0006 0.0243
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0028 0.0012 0.0012
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0006 0.0006
Echinococcus multilocularis sugar phosphate exchanger 3 0.0014 0.0002 0.0002
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0131 0.0081 0.4531
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0006 0.0323
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Plasmodium falciparum thioredoxin reductase 0.0058 0.0031 0.9735
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus g protein coupled receptor 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.0131 0.0081 0.4531
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0022 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Schistosoma mansoni biogenic amine receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0074 0.0042 0.0042
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0001 0.0001
Echinococcus granulosus serotonin receptor 0.0032 0.0014 0.0014
Entamoeba histolytica major facilitator superfamily transporter, putative 0.0014 0.0002 0.0685
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0025 0.0027
Trypanosoma brucei drug resistence protein, putative 0.0014 0.0002 0.0002
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0167 0.0105 0.0105
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0005
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.0014 0.0014
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0028 0.0012 0.0012
Trypanosoma brucei trypanothione reductase 0.0058 0.0031 0.0036
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Trypanosoma brucei transporter, putative 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Onchocerca volvulus 0.0014 0.0002 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) glutathione reductase 0.0058 0.0031 0.0031
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Echinococcus multilocularis sodium and chloride dependent glycine 0.0028 0.0012 0.0012
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0156 0.0098 0.0111
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0017 0.5286
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.0014 0.0014
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0032 1
Trypanosoma cruzi phospholipase A1, putative 0.034 0.0222 0.0252
Schistosoma mansoni ap endonuclease 0.002 0.0006 0.0006
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0006 0.0007
Echinococcus granulosus thioredoxin glutathione reductase 0.0058 0.0031 0.0031
Echinococcus granulosus survival motor neuron protein 1 0.0252 0.0162 0.0162
Brugia malayi glutathione reductase 0.0058 0.0031 0.0031
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.0014 0.0014
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Echinococcus granulosus synaptic vesicular amine transporter 0.0014 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0059 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Trypanosoma brucei protein associated with differentiation 4, putative 0.0014 0.0002 0.0002
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.0014 0.0014
Schistosoma mansoni selectively expressed in embryonic epithelia protein-1 0.0014 0.0002 0.0002
Trypanosoma cruzi major facilitator superfamily, putative 0.0014 0.0002 0.0001
Onchocerca volvulus 0.0014 0.0002 0.0001
Trypanosoma cruzi transporter, putative 0.0014 0.0002 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Leishmania major transporter, putative,major facilitator superfamily protein (MFS), putative 0.0014 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0014 0.0002 0.0685
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0006 0.1862
Echinococcus multilocularis monocarboxylate transporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Trichomonas vaginalis Hexuronate transporter, putative 0.0014 0.0002 0.009
Toxoplasma gondii hypothetical protein 0.0014 0.0002 0.0525
Plasmodium falciparum pantothenate transporter 0.0014 0.0002 0.0525
Schistosoma mansoni opsin-like receptor 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0006 0.0006
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.034 0.0222 0.0222
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0014 0.0014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0016 0.0016
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.0014 0.0014
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0006 0.0268
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Brugia malayi probable sodium-dependent inorganic phosphate cotransporter 0.0014 0.0002 0.0002
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein 0.0014 0.0002 0.0001
Leishmania major phospholipase A1, putative 0.034 0.0222 0.0253
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0022 0.0022
Loa Loa (eye worm) norepinephrine transporter 0.0167 0.0105 0.0105
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Echinococcus granulosus fmrfamide receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0032 0.0014 0.0014
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Schistosoma mansoni amine GPCR 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0108 0.0065 0.0065
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0008 0.042
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0022 0.0024
Schistosoma mansoni hypothetical protein 0.0628 0.0415 0.0415
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0006 0.1849
Trypanosoma brucei Protein Associated with Differentiation 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Probable oxidoreductase 0.0273 0.0176 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.0014 0.0014
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0034 0.0015 0.0015
Toxoplasma gondii hypothetical protein 0.0014 0.0002 0.0525
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0042 0.0042
Trypanosoma cruzi major facilitator superfamily, putative 0.0014 0.0002 0.0001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.0012
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0006 0.259
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0008 0.0008
Brugia malayi Pre-SET motif family protein 0.0036 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0167 0.0105 0.0105
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0014 0.0002 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.0014 0.0014
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0006 0.0006
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Leishmania major hypothetical protein, unknown function 0.0014 0.0002 0.0002
Trypanosoma cruzi transporter, putative 0.0014 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Echinococcus multilocularis monocarboxylate transporter 0.0014 0.0002 0.0002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.0014 0.0014
Echinococcus granulosus importin subunit beta 1 0.0059 0.0032 0.0032
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Schistosoma mansoni adenylate cyclase 0.0014 0.0002 0.0002
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0022 0.6744
Echinococcus granulosus bloom syndrome protein 0.0023 0.0008 0.0008
Brugia malayi Phospholipase A2 family protein 0.0612 0.0404 0.0404
Onchocerca volvulus Phospholipase A2 homolog 0.0612 0.0404 0.0404
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Plasmodium falciparum importin beta, putative 0.0059 0.0032 1
Echinococcus granulosus g protein coupled receptor 0.0032 0.0014 0.0014
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0006 0.0006
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0014 0.0014
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Onchocerca volvulus 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0167 0.0105 0.0105
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.0028 0.0012 0.0012
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Onchocerca volvulus 0.0014 0.0002 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0059 0.0059
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Schistosoma mansoni neuropeptide receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0014 0.0002 0.0002
Onchocerca volvulus 0.034 0.0222 0.0221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0017 0.0017
Onchocerca volvulus Sialin homolog 0.0014 0.0002 0.0001
Echinococcus multilocularis oxalate:formate antiporter 0.0014 0.0002 0.0002
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0028 0.0012 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0032 0.0014 0.0014
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0006 0.0268
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0014 0.0002 0.0001
Echinococcus multilocularis protein spinster 0.0014 0.0002 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.0014 0.0014
Schistosoma mansoni opsin-like receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.0014 0.0014
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0131 0.0081 0.4531
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0014 0.0002 0.0002
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0014 0.0002 0.0001
Brugia malayi ERG2 and Sigma1 receptor like protein 1.3016 0.8755 0.8755
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0022 0.6744
Toxoplasma gondii hypothetical protein 0.0014 0.0002 0.0525
Schistosoma mansoni sialin (solute carrier family 17 member 5) (sodium/sialic acid cotransporter) (ast) (membrane glycoprotein hp59) 0.0014 0.0002 0.0002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0006 0.0007
Onchocerca volvulus Putative solute carrier family 17, member 7 0.0014 0.0002 0.0001
Trypanosoma brucei major facilitator superfamily, putative 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Trichomonas vaginalis transport proetin, putative 0.0014 0.0002 0.009
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.3617
Plasmodium vivax thioredoxin reductase, putative 0.0058 0.0031 0.9735
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0006 0.0006
Schistosoma mansoni neuropeptide receptor 0.0032 0.0014 0.0014
Schistosoma mansoni solute carrier family 17 member 7 (vesicular glutamate transporter 0.0014 0.0002 0.0002
Echinococcus multilocularis snurportin 1 0.0628 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0014 0.0002 0.0525
Echinococcus multilocularis Glycerol 3 phosphate transporter 0.0014 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Brugia malayi hypothetical protein 0.0014 0.0002 0.0002
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0288 0.0187 0.0186
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0015 0.0015
Echinococcus granulosus serotonin transporter 0.0167 0.0105 0.0105
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Trypanosoma cruzi integral membrane transport protein, putative 0.0014 0.0002 0.0001
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0022 0.0022
Trypanosoma brucei major facilitator superfamily, putative 0.0014 0.0002 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.0014 0.0014
Mycobacterium tuberculosis Probable oxidoreductase 0.0146 0.0091 0.5095
Loa Loa (eye worm) hypothetical protein 0.0034 0.0015 0.0015
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0006 0.1849
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis Hippocampus abundant transcript 1 protein 0.0014 0.0002 0.0002
Onchocerca volvulus Uncharacterized transporter homolog 0.0014 0.0002 0.0001
Trypanosoma brucei major facilitator superfamily, putative 0.0014 0.0002 0.0002
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0006 0.0318
Echinococcus granulosus protein spinster 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0058 0.0031 0.0035
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.0014 0.0014
Echinococcus granulosus dna polymerase eta 0.0021 0.0006 0.0006
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0032 0.0037
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0022 1
Trypanosoma brucei transporter, putative 0.0014 0.0002 0.0002
Echinococcus multilocularis sodium and chloride dependent glycine 0.0028 0.0012 0.0012
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.0014 0.0014
Leishmania major MFS transporter, putative 0.0014 0.0002 0.0002
Echinococcus multilocularis serotonin receptor 0.0032 0.0014 0.0014
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0032 0.0014 0.0014
Trichomonas vaginalis sucrose transport protein, putative 0.0014 0.0002 0.009
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Plasmodium vivax sugar transporter, putative 0.0014 0.0002 0.0525
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0017 0.0017
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Echinococcus multilocularis transfer RNA-Leu 0.0014 0.0002 0.0002
Brugia malayi Importin beta-1 subunit 0.0059 0.0032 0.0032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.3617
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Brugia malayi AKH receptor 0.0032 0.0014 0.0014
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0002 0.009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni myosin xvIII 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Echinococcus granulosus sodium and chloride dependent glycine 0.0028 0.0012 0.0012
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0028 0.0012 0.0012
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0006 0.0342
Loa Loa (eye worm) solute carrier family 6 member 4 0.0167 0.0105 0.0105
Onchocerca volvulus 0.034 0.0222 0.0221
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0006 0.1876
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0015 0.0015
Leishmania major DNA polymerase eta, putative 0.0021 0.0006 0.0007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0014 0.0002 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0006 0.0006
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0025 0.1319
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Leishmania major C-8 sterol isomerase-like protein 1.3016 0.8755 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0006 0.2129
Schistosoma mansoni phosphate transporter 0.0014 0.0002 0.0002
Echinococcus granulosus feline leukemia virus subgroup C 0.0014 0.0002 0.0002
Trichomonas vaginalis set domain proteins, putative 0.0288 0.0187 1
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.0014 0.0014
Echinococcus granulosus oxalate:formate antiporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0006 0.0006
Echinococcus multilocularis vesicular glutamate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0059 0.0059
Schistosoma mansoni monocarboxylate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni sodium/sialic acid cotransporter 0.0014 0.0002 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0014 0.0014
Schistosoma mansoni ap endonuclease 0.002 0.0006 0.0006
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.0012
Leishmania major hypothetical protein, unknown function 0.0014 0.0002 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0002 0.0002
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0014 0.0002 0.0525
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0006
Echinococcus multilocularis monocarboxylate transporter 0.0014 0.0002 0.0002
Schistosoma mansoni amine GPCR 0.0032 0.0014 0.0014
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.0014 0.0014
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0108 0.0065 0.0065
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0014 0.0002 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0006 0.0006
Onchocerca volvulus Vesicular acetylcholine transporter homolog 1.4865 1 1
Trypanosoma cruzi protein associated with differentiation 4, putative 0.0014 0.0002 0.0001
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.0014 0.0014
Plasmodium vivax transporter, putative 0.0014 0.0002 0.0525
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0028 0.0012 0.3617
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi Abnormal catecholamine distribution protein 1 0.0014 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Echinococcus granulosus Glycerol 3 phosphate transporter 0.0014 0.0002 0.0002
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0014 0.0002 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0014 0.0014
Entamoeba histolytica phosphate transporter, putative 0.0014 0.0002 0.0685
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0006 0.0006
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0014 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Entamoeba histolytica Ran family GTPase 0.0043 0.0022 0.8795
Plasmodium vivax transporter, putative 0.0014 0.0002 0.0525
Onchocerca volvulus 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Entamoeba histolytica transporter, major facilitator family 0.0014 0.0002 0.0685
Trypanosoma brucei major facilitator superfamily, putative 0.0014 0.0002 0.0002
Schistosoma mansoni sodium-dependent phosphate transporter 0.0014 0.0002 0.0002
Trypanosoma brucei unspecified product 0.0014 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0002 0.0001
Plasmodium vivax metabolite/drug transporter, putative 0.0014 0.0002 0.0525
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.0014 0.0014
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.0014 0.0014
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi hypothetical protein 0.0028 0.0012 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Trypanosoma cruzi major facilitator superfamily, putative 0.0014 0.0002 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0014 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0003 0.0858
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0002 0.0002
Trypanosoma brucei major facilitator superfamily, putative 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Echinococcus granulosus orexin receptor type 2 0.0032 0.0014 0.0014
Leishmania major GTP-binding protein, putative 0.0043 0.0022 0.0025
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0006 0.0006
Schistosoma mansoni oxalate:formate antiporter 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0131 0.0081 0.4531
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.0014 0.0014
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0006 0.0009
Entamoeba histolytica major facilitator superfamily protein 0.0014 0.0002 0.0685
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Onchocerca volvulus 0.0032 0.0014 0.0014
Schistosoma mansoni sodium-dependent amino acid transporter 0.0028 0.0012 0.0012
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0014 0.0002 0.0002
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Brugia malayi G-protein coupled receptor 0.0032 0.0014 0.0014
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0006 0.0007
Echinococcus granulosus geminin 0.0387 0.0253 0.0253
Onchocerca volvulus 0.0014 0.0002 0.0001
Echinococcus granulosus monocarboxylate transporter 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0032 0.0014 0.0014
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0014 0.0002 0.0002
Trypanosoma cruzi transporter, putative 0.0014 0.0002 0.0001
Echinococcus multilocularis synaptic vesicular amine transporter 0.0014 0.0002 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0002 0.0525
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 1.3016 0.8755 0.8755
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.0014 0.0014
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0028 0.0012 0.0012
Onchocerca volvulus 0.0032 0.0014 0.0014
Brugia malayi G protein-coupled receptor 0.0032 0.0014 0.0014
Trypanosoma cruzi C-8 sterol isomerase, putative 1.3016 0.8755 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Schistosoma mansoni sugar transporter 0.0014 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0014 0.0014
Trypanosoma brucei phospholipase A1, putative 0.034 0.0222 0.0253
Brugia malayi hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi GnHR receptor homolog 0.0032 0.0014 0.0014
Echinococcus multilocularis monocarboxylate transporter 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0006 0.0007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0015 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0006 0.0268
Loa Loa (eye worm) hypothetical protein 0.6653 0.4471 0.4471
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0014 0.0014
Schistosoma mansoni sodium/chloride dependent transporter 0.0167 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0014
Brugia malayi follicle stimulating hormone receptor 0.0278 0.018 0.018
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0006 0.9805

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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