Detailed information for compound 801183

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 459.507 | Formula: C25H30FNO6
  • H donors: 1 H acceptors: 3 LogP: 3.21 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C1C(C)CC2=C(C1=O)C(c1cccc(c1)F)/C(=C(/OCCOC(C)C)\O)/C(=N2)C
  • InChi: 1S/C25H30FNO6/c1-13(2)32-9-10-33-25(30)20-15(4)27-18-11-14(3)19(24(29)31-5)23(28)22(18)21(20)16-7-6-8-17(26)12-16/h6-8,12-14,19,21,30H,9-11H2,1-5H3
  • InChiKey: CAELZMQXWUUHNO-UHFFFAOYSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0963 0.0956
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0748 0.1294
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0037 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.1081 0.1074
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0235 0.0423
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.1046 0.6661
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0116 0.0116
Plasmodium falciparum heat shock protein 90 0.0035 0.023 0.0414
Echinococcus multilocularis General substrate transporter 0.0096 0.0949 0.0942
Echinococcus granulosus lamin dm0 0.0027 0.0142 0.0135
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0073 0.0421
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0181 0.195 0.5509
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1082 0.1878
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0748 0.0741
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0238 0.0428
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0235 0.0423
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Toxoplasma gondii exonuclease III APE 0.0019 0.0042 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1403 0.3312
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.014 0.0375
Brugia malayi Cytochrome P450 family protein 0.002 0.0058 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0375 0.0368
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.014 0.0314
Schistosoma mansoni survival motor neuron protein 0.0097 0.0963 0.0963
Echinococcus multilocularis cysteine protease 0.0035 0.0238 0.0231
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0042 0.0081
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0235 0.0646
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Schistosoma mansoni ap endonuclease 0.0019 0.0042 0.0042
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0229 0.1424
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0015 0.0046
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0681 0.0674
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0039 0.0281 0.0777
Onchocerca volvulus 0.0079 0.0748 0.0741
Giardia lamblia Tenascin-X 0.0024 0.0101 0.0599
Loa Loa (eye worm) hypothetical protein 0.0192 0.2071 0.2065
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0015 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0015 0.0013
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.014 0.0314
Toxoplasma gondii cathepsin CPL 0.0035 0.0238 0.0654
Brugia malayi hypothetical protein 0.002 0.0057 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Loa Loa (eye worm) fli-1 protein 0.0222 0.2427 0.2422
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Plasmodium falciparum protein kinase 6 0.0475 0.5392 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0748 0.1757
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0235 0.0228
Toxoplasma gondii facilitative glucose transporter GT1 0.0112 0.1133 0.3191
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0042 0.2448
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0149 0.1567 0.156
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0015 0.0013
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0748 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0065 0.0057
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0065 0.0065
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni Smad4 0.0017 0.0027 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0065 0.0057
Echinococcus multilocularis calcium dependent protein kinase 0.0032 0.02 0.0192
Brugia malayi Smad1 0.0017 0.0027 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0748 0.0748
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Echinococcus granulosus geminin 0.0526 0.5992 0.5989
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Brugia malayi MAP kinase sur-1 0.0104 0.1046 0.1039
Onchocerca volvulus 0.0035 0.0238 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0229 0.1424
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1133 0.7219
Entamoeba histolytica cysteine protease, putative 0.0035 0.0238 0.1012
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Brugia malayi MH2 domain containing protein 0.0255 0.2819 0.2813
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0149 0.1567 0.37
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0033 0.0216 0.0209
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.014 0.0314
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0543 0.1271
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0057 0.0049
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0065 0.0065
Echinococcus granulosus calcium dependent protein kinase 0.0032 0.02 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Plasmodium vivax heat shock protein 86, putative 0.0035 0.023 0.0414
Brugia malayi nuclear receptor NHR-88 0.0021 0.0065 0.0057
Echinococcus granulosus fibrillin 1 0.0024 0.0101 0.0093
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.023 0.0529
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0216 0.0216
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0015 0.0046
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0015 0.0017
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0748 0.1294
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0065 0.0057
Echinococcus granulosus vesicular acetylcholine transporter 0.0867 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0238 0.1012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0065 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0898 0.0898
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0149 0.1567 0.1567
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0229 0.0527
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0123 0.1266 0.2987
Toxoplasma gondii heat shock protein HSP90 0.0035 0.023 0.0632
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0101 0.0094
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Trypanosoma brucei protein kinase, putative 0.0104 0.1046 0.2464
Loa Loa (eye worm) sugar transporter 0.0112 0.1133 0.1126
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0748 0.475
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Onchocerca volvulus 0.0024 0.0101 0.0094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0898 0.0892
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0015 0.0017
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0057 0.0049
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0027 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0072 0.0112
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0414 0.0414
Brugia malayi Cytochrome P450 family protein 0.002 0.0058 0.005
Giardia lamblia hypothetical protein 0.0024 0.0101 0.0599
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0142 0.0135
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0187 0.2024 0.2018
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0094
Treponema pallidum heat shock protein 90 0.0028 0.0148 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1082 0.1878
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0898 0.0892
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0149 0.1567 0.1567
Leishmania major glucose transporter, lmgt3 0.0035 0.0229 0.0527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0529 0.091
Loa Loa (eye worm) hypothetical protein 0.0476 0.5411 0.5407
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0042 0.022
Brugia malayi MH2 domain containing protein 0.0017 0.0027 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0748 0.0748
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0042 0.0024
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Schistosoma mansoni transcription factor LCR-F1 0.0187 0.2024 0.2024
Plasmodium vivax CDK-related protein kinase 6, putative 0.0475 0.5392 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0037 0.007
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0072 0.0112
Plasmodium falciparum thioredoxin reductase 0.0016 0.0015 0.0013
Schistosoma mansoni integrin beta subunit 0.0432 0.4894 0.4894
Mycobacterium tuberculosis Conserved protein 0.0079 0.0748 0.1294
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0.023 0.0529
Onchocerca volvulus 0.0024 0.0101 0.0093
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0065 0.0057
Brugia malayi MH2 domain containing protein 0.0017 0.0027 0.002
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0149 0.1567 0.156
Leishmania major glucose transporter, lmgt1 0.0035 0.0229 0.0527
Schistosoma mansoni vesicular acetylcholine transporter 0.0867 1 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0015 0.0507
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0405 0.0398
Schistosoma mansoni ero1-related 0.0054 0.0461 0.0461
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0065 0.0057
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0007
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0681 0.0674
Echinococcus multilocularis cathepsin L 0.0018 0.0037 0.003
Echinococcus multilocularis heat shock protein 0.0035 0.023 0.0223
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0543 0.0536
Brugia malayi MH1 domain containing protein 0.0017 0.0027 0.002
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Onchocerca volvulus 0.002 0.0057 0.0049
Plasmodium vivax vivapain-3 0.0018 0.0037 0.0055
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0229 0.0527
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0235 0.0228
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0529 0.7035
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Giardia lamblia Heat shock protein HSP 90-alpha 0.0035 0.023 0.143
Leishmania major cathepsin L-like protease 0.0135 0.1403 0.3312
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Leishmania major hypothetical protein, conserved 0.0027 0.014 0.0314
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0529 0.7035
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0238 0.1479
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0543 0.0936
Onchocerca volvulus 0.0035 0.0238 0.0231
Plasmodium vivax glutathione reductase, putative 0.0047 0.0375 0.0683
Toxoplasma gondii thioredoxin reductase 0.0047 0.0375 0.1043
Plasmodium falciparum endoplasmin, putative 0.0021 0.0073 0.0122
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.1046 0.2464
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0065 0.0057
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0148 0.0898
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1403 0.3312
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Brugia malayi Thioredoxin reductase 0.0047 0.0375 0.0368
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.1663 0.1657
Trypanosoma brucei trypanothione reductase 0.0047 0.0375 0.0873
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0065 0.0057
Loa Loa (eye worm) glutathione reductase 0.0047 0.0375 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0065 0.0057
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0157 0.1663 0.1657
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0015 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0529 0.0529
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0065 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0065 0.0057
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0681 0.0674
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0116 0.1461
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0065 0.0057
Giardia lamblia Lysyl-tRNA synthetase 0.0025 0.0116 0.0694
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0058 0.0119
Echinococcus multilocularis adam 0.0024 0.0101 0.0093
Loa Loa (eye worm) hypothetical protein 0.005 0.0405 0.0398
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0065 0.0057
Trypanosoma brucei glucose transporter 2A 0.0035 0.0229 0.0527
Echinococcus granulosus lamin 0.0027 0.0142 0.0135
Echinococcus granulosus survival motor neuron protein 1 0.0476 0.5411 0.5407
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Echinococcus granulosus adam 0.0024 0.0101 0.0093
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.014 0.0246
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0529 0.1477
Trypanosoma cruzi heat shock protein 85, putative 0.0028 0.0148 0.0332
Leishmania major C-8 sterol isomerase-like protein 0.0375 0.4222 1
Echinococcus granulosus ubiquitin specific protease 41 0.0149 0.1567 0.156
Echinococcus granulosus cysteine protease 0.0018 0.0037 0.003
Onchocerca volvulus 0.0035 0.0238 0.0231
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.1046 0.2464
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0101 0.0322
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Schistosoma mansoni hypothetical protein 0.0187 0.2024 0.2024
Entamoeba histolytica hypothetical protein 0.0025 0.0116 0.0396
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0033 0.0216 0.0902
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0058 0.005
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0235 0.0423
Loa Loa (eye worm) hypothetical protein 0.0112 0.1132 0.1125
Echinococcus multilocularis microtubule associated protein 2 0.0701 0.8048 0.8047
Onchocerca volvulus 0.005 0.0414 0.0407
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0238 0.1012
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0015 0.0007
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.1223 0.2123
Schistosoma mansoni ets-related 0.0222 0.2427 0.2427
Brugia malayi lysyl-tRNA synthetase 0.0025 0.0116 0.0108
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0007 0.0007
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.1046 0.1046
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.014 0.0246
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0142 0.0135
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0235 0.0423
Brugia malayi Kelch motif family protein 0.0112 0.1132 0.1125
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0017 0.0009
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0238 0.0547
Schistosoma mansoni hypothetical protein 0.0526 0.5992 0.5992
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0065 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Schistosoma mansoni polycystin 1-related 0.002 0.0057 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0058 0.0119
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0037 0.007
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0042 0.2045
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0543 0.0536
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0028 0.0148 0.014
Chlamydia trachomatis lysine--tRNA ligase 0.0025 0.0116 1
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Echinococcus multilocularis tumor protein p63 0.0344 0.3857 0.3852
Giardia lamblia High cysteine protein 0.0024 0.0101 0.0599
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0015 0.0096
Echinococcus granulosus intermediate filament protein 0.0027 0.0142 0.0135
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0065 0.0065
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0748 0.1294
Schistosoma mansoni heat shock protein 0.0035 0.023 0.023
Schistosoma mansoni gabp alpha 0.0073 0.0681 0.0681
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0027 0.002
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0028 0.0148 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0015 0.0017
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0065 0.0065
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0235 0.0646
Mycobacterium leprae Probable lipase LipE 0.0079 0.0748 0.5877
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0037 0.0037
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0065 0.0057
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0027 0.002
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0007
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0045 0.009
Loa Loa (eye worm) heat shock protein 90 0.0035 0.023 0.0223
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Trypanosoma cruzi endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.1077
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0028 0.0148 0.0245
Leishmania major cytochrome p450-like protein 0.002 0.0058 0.0119
Plasmodium vivax unspecified product 0.0018 0.0037 0.0055
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0037 0.0055
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Echinococcus multilocularis fibrillin 2 0.0024 0.0101 0.0093
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0094
Echinococcus multilocularis protein jagged 2 0.0024 0.0101 0.0093
Echinococcus granulosus GPCR family 2 0.005 0.0405 0.0398
Brugia malayi ecdysteroid receptor 0.0021 0.0065 0.0057
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0405 0.0398
Brugia malayi beta-lactamase family protein 0.0079 0.0748 0.0741
Leishmania major cathepsin L-like protease 0.0135 0.1403 0.3312
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0112 0.1133 0.1126
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0142 0.0135
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis musashi 0.0027 0.0142 0.0135
Trichomonas vaginalis heat shock protein, putative 0.0035 0.023 0.143
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0065 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.1046 0.1039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0037 0.0189
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0238 0.0547
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Trypanosoma brucei pol-associated gene 1 0.0054 0.0461 0.1077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0149 0.1567 0.7699
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0235 0.0423
Schistosoma mansoni lipoxygenase 0.0056 0.0477 0.0477
Onchocerca volvulus 0.0035 0.0238 0.0231
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0748 0.475
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0238 0.1479
Entamoeba histolytica protein kinase, putative 0.0035 0.0235 0.0998
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Mycobacterium ulcerans beta-lactamase 0.0079 0.0748 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0017 0.0009
Onchocerca volvulus 0.002 0.0057 0.0049
Plasmodium falciparum mitogen-activated protein kinase 2 0.0181 0.195 0.3608
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0042 0.0081
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.1046 0.1039
Plasmodium falciparum endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.0843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0065 0.0057
Echinococcus granulosus lysyl tRNA synthetase 0.0025 0.0116 0.0108
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0042 0.022
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0375 0.0642
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0238 0.0231
Echinococcus multilocularis lamin 0.0027 0.0142 0.0135
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0037 0.003
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0112 0.1132 0.1125
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0065 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0037 0.0189
Mycobacterium tuberculosis Conserved protein 0.0079 0.0748 0.1294
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0543 0.0543
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Echinococcus granulosus cathepsin l1 0.0035 0.0238 0.0231
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0015 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0028 0.0148 0.0332
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0898 0.0898
Echinococcus multilocularis fibrillin 1 0.0024 0.0101 0.0093
Echinococcus multilocularis smad 0.0017 0.0027 0.002
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0495 0.0488
Echinococcus granulosus Endoplasmic reticulum oxidoreductin 1 0.0054 0.0461 0.0454
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0182 0.0175
Plasmodium falciparum glutathione reductase 0.0016 0.0015 0.0013
Brugia malayi Cathepsin L-like precursor 0.0024 0.0101 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Schistosoma mansoni hypothetical protein 0.0112 0.1133 0.1133
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.014 0.0246
Trypanosoma brucei Heat shock protein 83, putative 0.0035 0.023 0.0529
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0065 0.0057
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0375 0.0368
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0529 0.0521
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0057 0.0049
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0229 0.0527
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0065 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0065 0.0057
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0037 0.007
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0867 1 1
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.023 0.0529
Giardia lamblia Tenascin precursor 0.0024 0.0101 0.0599
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0015 0.002
Brugia malayi Ets-domain containing protein 0.0073 0.0681 0.0674
Echinococcus multilocularis heat shock protein 90 0.0028 0.0148 0.014
Loa Loa (eye worm) hypothetical protein 0.0107 0.1081 0.1074
Toxoplasma gondii lysine-tRNA ligase 0.0025 0.0116 0.0307
Leishmania major trypanothione reductase 0.0047 0.0375 0.0873
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0057 0.0092
Loa Loa (eye worm) doublecortin family protein 0.002 0.0057 0.0049
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0025 0.0116 0.0383
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0027 0.002
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0028 0.0148 0.066
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0116 0.0116
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.1046 0.2464
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.1046 0.1039
Schistosoma mansoni glucose transport protein 0.0112 0.1133 0.1133
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0149 0.1567 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0216 0.0209
Brugia malayi beta-lactamase 0.0079 0.0748 0.0741
Echinococcus multilocularis geminin 0.0526 0.5992 0.5989
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0065 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0748 0.1757
Loa Loa (eye worm) CYP4Cod1 0.002 0.0058 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0096
Giardia lamblia Tenascin-37 0.0024 0.0101 0.0599
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Loa Loa (eye worm) endoplasmin 0.0035 0.023 0.0223
Giardia lamblia Prolyl-tRNA synthetase 0.0033 0.0216 0.1339
Loa Loa (eye worm) hypothetical protein 0.0027 0.014 0.0132
Plasmodium falciparum hexose transporter 0.0112 0.1133 0.209
Brugia malayi Sugar transporter family protein 0.0112 0.1133 0.1126
Trypanosoma brucei glucose transporter 1E 0.0035 0.0229 0.0527
Schistosoma mansoni ap endonuclease 0.0019 0.0042 0.0042
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0037 0.007
Echinococcus multilocularis survival motor neuron protein 1 0.0476 0.5411 0.5407
Schistosoma mansoni lamin 0.0027 0.0142 0.0142
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.1223 1
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1403 0.3312
Brugia malayi MH1 domain containing protein 0.0017 0.0027 0.002
Echinococcus granulosus General substrate transporter 0.0096 0.0949 0.0942
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0037 0.0037
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0108
Schistosoma mansoni loxhd1 0.002 0.0057 0.0057
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0235 0.054
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0149 0.1567 0.156
Trichomonas vaginalis esterase, putative 0.0079 0.0748 0.475
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0065 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Giardia lamblia Neurogenic locus Notch protein precursor 0.0024 0.0101 0.0599
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0229 0.0527
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.023 0.0529
Brugia malayi hypothetical protein 0.0187 0.2024 0.2018
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.1223 0.2123
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Plasmodium falciparum glutathione reductase 0.0047 0.0375 0.0683
Brugia malayi intermediate filament protein 0.0027 0.0142 0.0135
Plasmodium vivax proline--tRNA ligase, putative 0.0039 0.0281 0.0509
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Schistosoma mansoni rab6-interacting 0.002 0.0057 0.0057
Echinococcus granulosus cathepsin l1 0.0024 0.0101 0.0094
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0065 0.0057
Loa Loa (eye worm) cysteine protease 0.0035 0.0238 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0229 0.1424
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0503 0.5731 1
Schistosoma mansoni hypothetical protein 0.0526 0.5992 0.5992
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.1046 0.2464
Schistosoma mansoni heat shock protein 0.0035 0.023 0.023
Schistosoma mansoni glucose transporter 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0748 0.1375
Plasmodium vivax endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.0843
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0748 0.5877
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.1046 0.2464
Schistosoma mansoni protein kinase 0.0035 0.0235 0.0235
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0238 0.0231
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0148 0.0898
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0238 0.0231
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0748 0.475
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0065 0.0057
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0375 0.0683
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0149 0.1567 1
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Schistosoma mansoni protein kinase 0.0035 0.0235 0.0235
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0898 0.0892
Brugia malayi Fli-1 protein 0.0222 0.2427 0.2422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0101 0.06
Onchocerca volvulus 0.0035 0.0238 0.0231
Brugia malayi Doublecortin family protein 0.002 0.0057 0.0049
Echinococcus multilocularis integrin beta 2 0.0544 0.6203 0.62
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1082 0.1878
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Schistosoma mansoni coup transcription factor 0.0021 0.0065 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0042 0.0034
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0748 0.1294
Onchocerca volvulus 0.0079 0.0748 0.0741
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Onchocerca volvulus 0.0027 0.0142 0.0135
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0037 0.007
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0235 0.0423
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.1567 0.37
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0748 1
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0235 0.146
Loa Loa (eye worm) fibroinase 0.0035 0.0238 0.0231
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0216 0.0209
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Schistosoma mansoni hypothetical protein 0.0097 0.0963 0.0963
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1082 0.1878
Echinococcus granulosus tumor protein p63 0.0344 0.3857 0.3852
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0042 0.0081
Plasmodium vivax vivapain-1 0.0018 0.0037 0.0055
Schistosoma mansoni endoplasmin 0.0035 0.023 0.023
Echinococcus granulosus RUN 0.002 0.0057 0.0049
Plasmodium falciparum lysine--tRNA ligase 0.0025 0.0116 0.0201
Trypanosoma brucei cytochrome P450, putative 0.002 0.0058 0.0119
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0375 0.4222 0.4217
Mycobacterium ulcerans heat shock protein 90 0.0028 0.0148 0.1891
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0037 0.007
Schistosoma mansoni hypothetical protein 0.002 0.0057 0.0057
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0058 0.0676
Toxoplasma gondii endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.1286
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0065 0.0065
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0037 0.0037
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0027 0.002
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0238 0.0231
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0027 0.002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0187 0.2024 0.2018
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Echinococcus multilocularis Endoplasmic reticulum oxidoreductin 1 0.0054 0.0461 0.0454
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0033 0.0216 0.0209
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0065 0.0065
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0238 0.0231
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Echinococcus granulosus fibrillin 2 0.0024 0.0101 0.0093
Brugia malayi hypothetical protein 0.002 0.0057 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0065 0.0065
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0042 0.0034
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.1403 0.3312
Schistosoma mansoni glucose transport protein 0.0112 0.1133 0.1133
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Brugia malayi glutathione reductase 0.0047 0.0375 0.0368
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0042 0.0463
Schistosoma mansoni smad 0.0017 0.0027 0.0027
Trypanosoma brucei C-8 sterol isomerase, putative 0.0375 0.4222 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Loa Loa (eye worm) ctsf protein 0.0035 0.0238 0.0231
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.1046 0.2464
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.1567 1
Plasmodium vivax vivapain-2 0.0035 0.0238 0.0428
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0057 0.0049
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0065 0.0057
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0748 0.0741
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Loa Loa (eye worm) hypothetical protein 0.005 0.0414 0.0407
Plasmodium vivax endoplasmin, putative 0.0035 0.023 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0529 0.1236
Echinococcus multilocularis ubiquitin specific protease 41 0.0149 0.1567 0.156
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Leishmania major lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0257
Echinococcus multilocularis cysteine protease 0.0035 0.0238 0.0231
Echinococcus multilocularis lamin dm0 0.0027 0.0142 0.0135
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0149 0.1567 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0049
Echinococcus multilocularis endoplasmin 0.0028 0.0148 0.014
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Echinococcus granulosus heat shock protein 90 0.0028 0.0148 0.014
Mycobacterium ulcerans hypothetical protein 0.0079 0.0748 1
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0229 0.1424
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Loa Loa (eye worm) hypothetical protein 0.0149 0.1567 0.156
Leishmania major hypothetical protein, conserved 0.0079 0.0748 0.1757
Brugia malayi hypothetical protein 0.0112 0.1132 0.1125
Toxoplasma gondii hypothetical protein 0.0024 0.0101 0.0265
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0694
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0235 0.0423
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0235 0.0228
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0015 0.0507
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Plasmodium vivax hexose transporter 0.0112 0.1133 0.209
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0235 0.0235
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0065 0.0057
Echinococcus multilocularis Smad4 0.0017 0.0027 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0101 0.06
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0065 0.0057
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0015 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0748 0.475
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0543 0.7235
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0748 0.1757
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0238 0.0231
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0898 0.0898
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0065 0.0057
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0529 0.7035
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0477 0.047
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0065 0.0065
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0037 0.003
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0238 0.0238
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0867 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Schistosoma mansoni protein kinase 0.0035 0.0235 0.0235
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0748 0.475
Leishmania major protein kinase, putative 0.0035 0.0235 0.054
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0238 0.0428
Mycobacterium tuberculosis Probable reductase 0.0107 0.1082 0.1878
Brugia malayi Ets-domain containing protein 0.0073 0.0681 0.0674
Onchocerca volvulus 0.0035 0.0238 0.0231
Onchocerca volvulus 0.0035 0.0238 0.0231
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0042 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0143 0.0135
Echinococcus granulosus heat shock protein 90 0.0035 0.023 0.0223
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.1065 0.251
Entamoeba histolytica protein kinase, putative 0.0035 0.0235 0.0998
Loa Loa (eye worm) hypothetical protein 0.0054 0.0461 0.0454
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0015 0.0017
Plasmodium falciparum proline--tRNA ligase 0.0039 0.0281 0.0509
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0257
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0149 0.1567 0.156
Brugia malayi Cytochrome P450 family protein 0.0031 0.0182 0.0175
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0216 0.0216
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0065 0.0057
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0898 0.0892
Brugia malayi Latrophilin receptor protein 2 0.005 0.0405 0.0398
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.0148 0.0332
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0057 0.0049
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0238 0.0231
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0238 0.0238
Echinococcus multilocularis lysyl tRNA synthetase 0.0025 0.0116 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0229 0.1424
Loa Loa (eye worm) transcription factor SMAD2 0.0255 0.2819 0.2813
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0181 0.195 0.3608
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0033 0.0216 0.1257
Echinococcus granulosus heat shock protein 0.0035 0.023 0.0223
Loa Loa (eye worm) integrin beta-2 0.0544 0.6203 0.62
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0748 0.1294
Loa Loa (eye worm) hypothetical protein 0.0035 0.0238 0.0231
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0818 0.9418 0.9418
Giardia lamblia Grp94/Hsp90 0.0028 0.0148 0.0898
Brugia malayi hypothetical protein 0.0027 0.014 0.0132
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0033 0.0216 0.0209
Loa Loa (eye worm) hypothetical protein 0.0375 0.4222 0.4217
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0238 0.0231
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0405 0.0398
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0229 0.1424
Schistosoma mansoni microtubule-associated protein tau 0.0701 0.8048 0.8048
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Schistosoma mansoni endoplasmin 0.0035 0.023 0.023
Onchocerca volvulus 0.0079 0.0748 0.0741
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0015 0.0013
Echinococcus granulosus cathepsin L 0.0018 0.0037 0.003
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0064 0.0133
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0057 0.0049
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0101 0.0101
Schistosoma mansoni glucose transport protein 0.0112 0.1133 0.1133
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.023 0.0529
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0529 0.0521
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0065 0.0057
Brugia malayi hypothetical protein 0.0476 0.5411 0.5407
Echinococcus granulosus smad 0.0017 0.0027 0.002
Leishmania major glucose transporter, lmgt2 0.0035 0.0229 0.0527
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.023 0.0974
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Loa Loa (eye worm) beta-lactamase 0.0079 0.0748 0.0741
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0375 0.0873
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0065 0.0057
Brugia malayi beta-lactamase family protein 0.0079 0.0748 0.0741
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0748 0.0741
Plasmodium vivax lysine--tRNA ligase, putative 0.0025 0.0116 0.0201
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0405 0.0398
Mycobacterium tuberculosis Conserved protein 0.0079 0.0748 0.1294
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0015 0.0046
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.1567 0.37
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Schistosoma mansoni intermediate filament proteins 0.0027 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0035 0.0235 0.0228
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0235 0.0228
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.023 0.0974
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Brugia malayi hypothetical protein 0.0017 0.0028 0.002
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0042 0.022
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0477 0.047
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0235 0.0423
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Onchocerca volvulus 0.0027 0.0142 0.0135
Plasmodium falciparum thioredoxin reductase 0.0047 0.0375 0.0683
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0037 0.007
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0748 0.1294
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0065 0.0057
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0748 0.1294
Loa Loa (eye worm) hypothetical protein 0.0062 0.0557 0.055
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.1082 0.878
Giardia lamblia Neurogenic locus notch-like protein 0.0024 0.0101 0.0599
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0238 0.0231
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Brugia malayi heat shock protein 90 0.0035 0.023 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0065 0.0057
Schistosoma mansoni lamin 0.0027 0.0142 0.0142
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0065 0.0065
Onchocerca volvulus 0.0021 0.0065 0.0057
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Brugia malayi nuclear hormone receptor 0.0021 0.0065 0.0057
Echinococcus multilocularis GPCR, family 2 0.005 0.0405 0.0398
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0529 0.0529
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0065 0.0057
Echinococcus multilocularis vesicular acetylcholine transporter 0.0867 1 1
Leishmania major cathepsin L-like protease 0.0135 0.1403 0.3312
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0042 0.006
Echinococcus granulosus endoplasmin 0.0028 0.0148 0.014
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0235 0.0646
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0042 0.0064
Brugia malayi Endoplasmin precursor 0.0035 0.023 0.0223
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0238 0.0231
Loa Loa (eye worm) MH2 domain-containing protein 0.0255 0.2819 0.2813
Loa Loa (eye worm) Smad1 0.0017 0.0027 0.002
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0017 0.0126
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.023 0.0529
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0116 0.1461
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Brugia malayi cathepsin L-like precursor 0.0024 0.0101 0.0094
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0375 0.4222 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.1663 0.1657
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0238 0.0428
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0033 0.0216 0.1339
Toxoplasma gondii heat shock protein 90, putative 0.0035 0.023 0.0632
Toxoplasma gondii ABC1 family protein 0.0079 0.0748 0.21
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0257
Brugia malayi Integrin beta pat-3 precursor 0.0544 0.6203 0.62
Schistosoma mansoni hypothetical protein 0.0107 0.1081 0.1081
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0148 0.0898
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni rab6-interacting 0.002 0.0057 0.0057
Onchocerca volvulus 0.0097 0.0963 0.0956
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.1046 0.1039
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0748 0.0741
Echinococcus granulosus Smad4 0.0017 0.0027 0.002
Trypanosoma cruzi hexose transporter 0.0035 0.0229 0.0527
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.1223 0.2123
Trypanosoma cruzi Heat shock protein 83, putative 0.0035 0.023 0.0529
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0065 0.0057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0375 0.0368
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0042 0.0034
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0137 0.0129
Schistosoma mansoni lipoxygenase 0.002 0.0057 0.0057
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.008 0.0463
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0238 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0405 0.0398
Brugia malayi steroid hormone receptor 0.0021 0.0065 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0229 0.1424
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0042 0.0034
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1082 0.1878
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0235 0.0423
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Brugia malayi Cam kinase protein 1 0.0035 0.0235 0.0228
Giardia lamblia Tenascin-like 0.0024 0.0101 0.0599
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.1046 0.2464
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.1663 0.1657
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0898 0.0892
Echinococcus multilocularis heat shock protein 90 0.0035 0.023 0.0223
Plasmodium falciparum protein kinase 7 0.0316 0.3534 0.6549
Echinococcus multilocularis RUN 0.002 0.0057 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0065 0.0057
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0024 0.0101 0.0599
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0898 0.0892
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0149 0.1567 0.156
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Trichomonas vaginalis hypothetical protein 0.0024 0.0101 0.0599
Plasmodium vivax vivapain-2 0.0035 0.0238 0.0428
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0058 0.005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0065 0.0057
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0142 0.0135
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0238 0.0231
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0065 0.0065
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Echinococcus granulosus integrin beta 2 0.0544 0.6203 0.62
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0033 0.0216 0.0209
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.1567 0.37
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0405 0.0398
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0543 0.7235
Mycobacterium ulcerans lipase LipD 0.0079 0.0748 1
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.1046 0.1039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0009
Echinococcus granulosus microtubule associated protein 2 0.0701 0.8048 0.8047
Giardia lamblia High cysteine protein 0.0024 0.0101 0.0599
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0065 0.0057
Brugia malayi Endoplasmic Reticulum Oxidoreductin 1 0.0054 0.0461 0.0454
Leishmania major endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.1077
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0042 0.0081
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0065 0.0065
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.1046 0.2945
Toxoplasma gondii protein kinase, putative 0.0316 0.3534 1
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0057 0.0092
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0543 0.0536
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0073 0.0421
Giardia lamblia Heat shock protein HSP 90-alpha 0.0028 0.0148 0.0898
Brugia malayi Cathepsin L-like precursor 0.0024 0.0101 0.0094

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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