Detailed information for compound 801365

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 445.481 | Formula: C24H28FNO6
  • H donors: 1 H acceptors: 3 LogP: 2.78 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOCCOC(=C1C(=NC2=C(C1c1cccc(c1)F)C(=O)C(C(C2)C)C(=O)OC)C)O
  • InChi: 1S/C24H28FNO6/c1-5-31-9-10-32-24(29)19-14(3)26-17-11-13(2)18(23(28)30-4)22(27)21(17)20(19)15-7-6-8-16(25)12-15/h6-8,12-13,18,20,29H,5,9-11H2,1-4H3
  • InChiKey: NSJNMUCINDSCIQ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0529 0.7035
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0037 0.003
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0477 0.047
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0065 0.0065
Schistosoma mansoni protein kinase 0.0035 0.0235 0.0235
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0867 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0238 0.0238
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0748 0.475
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0238 0.0428
Leishmania major protein kinase, putative 0.0035 0.0235 0.054
Echinococcus granulosus heat shock protein 90 0.0035 0.023 0.0223
Onchocerca volvulus 0.0035 0.0238 0.0231
Loa Loa (eye worm) hypothetical protein 0.0027 0.0143 0.0135
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0042 0.0064
Brugia malayi Ets-domain containing protein 0.0073 0.0681 0.0674
Mycobacterium tuberculosis Probable reductase 0.0107 0.1082 0.1878
Onchocerca volvulus 0.0035 0.0238 0.0231
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.1065 0.251
Entamoeba histolytica protein kinase, putative 0.0035 0.0235 0.0998
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Loa Loa (eye worm) hypothetical protein 0.0054 0.0461 0.0454
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0257
Plasmodium falciparum proline--tRNA ligase 0.0039 0.0281 0.0509
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0015 0.0017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0149 0.1567 0.156
Brugia malayi Cytochrome P450 family protein 0.0031 0.0182 0.0175
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0216 0.0216
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0065 0.0057
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0235 0.0228
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0235 0.0423
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0694
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0015 0.0507
Plasmodium vivax hexose transporter 0.0112 0.1133 0.209
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0235 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0065 0.0057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis Smad4 0.0017 0.0027 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0101 0.06
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0748 0.475
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0543 0.7235
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0015 0.0013
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0065 0.0057
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0748 0.1757
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0238 0.0231
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0898 0.0898
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0748 0.0741
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0065 0.0057
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Plasmodium vivax endoplasmin, putative 0.0035 0.023 0.0414
Loa Loa (eye worm) hypothetical protein 0.005 0.0414 0.0407
Echinococcus multilocularis ubiquitin specific protease 41 0.0149 0.1567 0.156
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0529 0.1236
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Echinococcus multilocularis cysteine protease 0.0035 0.0238 0.0231
Leishmania major lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0257
Echinococcus multilocularis endoplasmin 0.0028 0.0148 0.014
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0049
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0149 0.1567 1
Echinococcus multilocularis lamin dm0 0.0027 0.0142 0.0135
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Echinococcus granulosus heat shock protein 90 0.0028 0.0148 0.014
Mycobacterium ulcerans hypothetical protein 0.0079 0.0748 1
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0229 0.1424
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Leishmania major hypothetical protein, conserved 0.0079 0.0748 0.1757
Brugia malayi hypothetical protein 0.0112 0.1132 0.1125
Toxoplasma gondii hypothetical protein 0.0024 0.0101 0.0265
Loa Loa (eye worm) hypothetical protein 0.0149 0.1567 0.156
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0238 0.0231
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0027 0.002
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0027 0.002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0187 0.2024 0.2018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Echinococcus multilocularis Endoplasmic reticulum oxidoreductin 1 0.0054 0.0461 0.0454
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0033 0.0216 0.0209
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Echinococcus granulosus fibrillin 2 0.0024 0.0101 0.0093
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0238 0.0231
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0065 0.0065
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0065 0.0065
Brugia malayi hypothetical protein 0.002 0.0057 0.0049
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.1403 0.3312
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0042 0.0034
Schistosoma mansoni glucose transport protein 0.0112 0.1133 0.1133
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Brugia malayi glutathione reductase 0.0047 0.0375 0.0368
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0042 0.0463
Schistosoma mansoni smad 0.0017 0.0027 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Trypanosoma brucei C-8 sterol isomerase, putative 0.0375 0.4222 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.1046 0.2464
Loa Loa (eye worm) ctsf protein 0.0035 0.0238 0.0231
Plasmodium vivax vivapain-2 0.0035 0.0238 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.1567 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0057 0.0049
Loa Loa (eye worm) fibroinase 0.0035 0.0238 0.0231
Loa Loa (eye worm) hypothetical protein 0.0033 0.0216 0.0209
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0017
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Schistosoma mansoni hypothetical protein 0.0097 0.0963 0.0963
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1082 0.1878
Echinococcus granulosus tumor protein p63 0.0344 0.3857 0.3852
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0042 0.0081
Schistosoma mansoni endoplasmin 0.0035 0.023 0.023
Plasmodium vivax vivapain-1 0.0018 0.0037 0.0055
Plasmodium falciparum lysine--tRNA ligase 0.0025 0.0116 0.0201
Echinococcus granulosus RUN 0.002 0.0057 0.0049
Trypanosoma brucei cytochrome P450, putative 0.002 0.0058 0.0119
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0375 0.4222 0.4217
Mycobacterium ulcerans heat shock protein 90 0.0028 0.0148 0.1891
Schistosoma mansoni hypothetical protein 0.002 0.0057 0.0057
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0037 0.007
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0037 0.0037
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0065 0.0065
Toxoplasma gondii endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.1286
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0058 0.0676
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0898 0.0892
Schistosoma mansoni protein kinase 0.0035 0.0235 0.0235
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1082 0.1878
Brugia malayi Fli-1 protein 0.0222 0.2427 0.2422
Brugia malayi Doublecortin family protein 0.002 0.0057 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0101 0.06
Onchocerca volvulus 0.0035 0.0238 0.0231
Echinococcus multilocularis integrin beta 2 0.0544 0.6203 0.62
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Schistosoma mansoni coup transcription factor 0.0021 0.0065 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0748 0.1294
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0042 0.0034
Onchocerca volvulus 0.0079 0.0748 0.0741
Onchocerca volvulus 0.0027 0.0142 0.0135
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0037 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.1567 0.37
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0235 0.0423
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0748 1
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0235 0.146
Schistosoma mansoni rab6-interacting 0.002 0.0057 0.0057
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0065 0.0057
Echinococcus granulosus cathepsin l1 0.0024 0.0101 0.0094
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0229 0.1424
Loa Loa (eye worm) cysteine protease 0.0035 0.0238 0.0231
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.1046 0.2464
Schistosoma mansoni heat shock protein 0.0035 0.023 0.023
Schistosoma mansoni hypothetical protein 0.0526 0.5992 0.5992
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0503 0.5731 1
Schistosoma mansoni glucose transporter 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0748 0.1375
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0748 0.5877
Plasmodium vivax endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.0843
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0238 0.0231
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.1046 0.2464
Schistosoma mansoni protein kinase 0.0035 0.0235 0.0235
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0148 0.0898
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0238 0.0231
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0065 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0748 0.475
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0149 0.1567 1
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0375 0.0683
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Trichomonas vaginalis esterase, putative 0.0079 0.0748 0.475
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0149 0.1567 0.156
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0065 0.0057
Giardia lamblia Neurogenic locus Notch protein precursor 0.0024 0.0101 0.0599
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0229 0.0527
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.1223 0.2123
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Brugia malayi hypothetical protein 0.0187 0.2024 0.2018
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.023 0.0529
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Brugia malayi intermediate filament protein 0.0027 0.0142 0.0135
Plasmodium falciparum glutathione reductase 0.0047 0.0375 0.0683
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Plasmodium vivax proline--tRNA ligase, putative 0.0039 0.0281 0.0509
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.1567 0.37
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0405 0.0398
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0543 0.7235
Mycobacterium ulcerans lipase LipD 0.0079 0.0748 1
Echinococcus granulosus microtubule associated protein 2 0.0701 0.8048 0.8047
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.1046 0.1039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0065 0.0057
Giardia lamblia High cysteine protein 0.0024 0.0101 0.0599
Brugia malayi Endoplasmic Reticulum Oxidoreductin 1 0.0054 0.0461 0.0454
Leishmania major endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.1077
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0042 0.0081
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.1046 0.2945
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0065 0.0065
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0057 0.0092
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0543 0.0536
Toxoplasma gondii protein kinase, putative 0.0316 0.3534 1
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0073 0.0421
Giardia lamblia Heat shock protein HSP 90-alpha 0.0028 0.0148 0.0898
Brugia malayi Cathepsin L-like precursor 0.0024 0.0101 0.0094
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.1046 0.2464
Giardia lamblia Tenascin-like 0.0024 0.0101 0.0599
Echinococcus multilocularis heat shock protein 90 0.0035 0.023 0.0223
Plasmodium falciparum protein kinase 7 0.0316 0.3534 0.6549
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.1663 0.1657
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0898 0.0892
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0065 0.0057
Echinococcus multilocularis RUN 0.002 0.0057 0.0049
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0898 0.0892
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0024 0.0101 0.0599
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0149 0.1567 0.156
Trichomonas vaginalis hypothetical protein 0.0024 0.0101 0.0599
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0065 0.0057
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0058 0.005
Plasmodium vivax vivapain-2 0.0035 0.0238 0.0428
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.0142 0.0135
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0238 0.0231
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0065 0.0065
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0065 0.0057
Echinococcus granulosus integrin beta 2 0.0544 0.6203 0.62
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0033 0.0216 0.0209
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.1046 0.1039
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0748 0.0741
Echinococcus granulosus Smad4 0.0017 0.0027 0.002
Trypanosoma cruzi hexose transporter 0.0035 0.0229 0.0527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0065 0.0057
Trypanosoma cruzi Heat shock protein 83, putative 0.0035 0.023 0.0529
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.1223 0.2123
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0375 0.0368
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0042 0.0034
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Schistosoma mansoni lipoxygenase 0.002 0.0057 0.0057
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0137 0.0129
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0238 0.0231
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.008 0.0463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Brugia malayi steroid hormone receptor 0.0021 0.0065 0.0057
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0405 0.0398
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0042 0.0034
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0235 0.0423
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1082 0.1878
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0229 0.1424
Brugia malayi Cam kinase protein 1 0.0035 0.0235 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Brugia malayi Endoplasmin precursor 0.0035 0.023 0.0223
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0042 0.0064
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0235 0.0646
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0238 0.0231
Loa Loa (eye worm) MH2 domain-containing protein 0.0255 0.2819 0.2813
Loa Loa (eye worm) Smad1 0.0017 0.0027 0.002
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0017 0.0126
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0116 0.1461
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.023 0.0529
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0375 0.4222 1
Brugia malayi cathepsin L-like precursor 0.0024 0.0101 0.0094
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0238 0.0428
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0033 0.0216 0.1339
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.1663 0.1657
Toxoplasma gondii heat shock protein 90, putative 0.0035 0.023 0.0632
Toxoplasma gondii ABC1 family protein 0.0079 0.0748 0.21
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0025 0.0116 0.0257
Brugia malayi Integrin beta pat-3 precursor 0.0544 0.6203 0.62
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0148 0.0898
Schistosoma mansoni hypothetical protein 0.0107 0.1081 0.1081
Onchocerca volvulus 0.0097 0.0963 0.0956
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni rab6-interacting 0.002 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Plasmodium falciparum thioredoxin reductase 0.0047 0.0375 0.0683
Onchocerca volvulus 0.0027 0.0142 0.0135
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0037 0.007
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0748 0.1294
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0065 0.0057
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0748 0.1294
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.1082 0.878
Loa Loa (eye worm) hypothetical protein 0.0062 0.0557 0.055
Giardia lamblia Neurogenic locus notch-like protein 0.0024 0.0101 0.0599
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0065 0.0057
Brugia malayi heat shock protein 90 0.0035 0.023 0.0223
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0238 0.0231
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0065 0.0065
Schistosoma mansoni lamin 0.0027 0.0142 0.0142
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Brugia malayi nuclear hormone receptor 0.0021 0.0065 0.0057
Onchocerca volvulus 0.0021 0.0065 0.0057
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0229 0.0527
Echinococcus multilocularis GPCR, family 2 0.005 0.0405 0.0398
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0529 0.0529
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0065 0.0057
Leishmania major cathepsin L-like protease 0.0135 0.1403 0.3312
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0042 0.006
Echinococcus granulosus endoplasmin 0.0028 0.0148 0.014
Echinococcus multilocularis vesicular acetylcholine transporter 0.0867 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0375 0.0873
Loa Loa (eye worm) beta-lactamase 0.0079 0.0748 0.0741
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0065 0.0057
Plasmodium vivax lysine--tRNA ligase, putative 0.0025 0.0116 0.0201
Brugia malayi beta-lactamase family protein 0.0079 0.0748 0.0741
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0748 0.0741
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0405 0.0398
Mycobacterium tuberculosis Conserved protein 0.0079 0.0748 0.1294
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0015 0.0046
Schistosoma mansoni intermediate filament proteins 0.0027 0.0142 0.0142
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0149 0.1567 0.37
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0235 0.0228
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0235 0.0228
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.023 0.0974
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Brugia malayi hypothetical protein 0.0017 0.0028 0.002
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0477 0.047
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0042 0.022
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0235 0.0423
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0015 0.0013
Echinococcus granulosus cathepsin L 0.0018 0.0037 0.003
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0064 0.0133
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0057 0.0049
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0101 0.0101
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.023 0.0529
Schistosoma mansoni glucose transport protein 0.0112 0.1133 0.1133
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0529 0.0521
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.023 0.0974
Leishmania major glucose transporter, lmgt2 0.0035 0.0229 0.0527
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0065 0.0057
Brugia malayi hypothetical protein 0.0476 0.5411 0.5407
Echinococcus granulosus smad 0.0017 0.0027 0.002
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0898 0.0892
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.0148 0.0332
Brugia malayi Latrophilin receptor protein 2 0.005 0.0405 0.0398
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0057 0.0049
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0238 0.0238
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0238 0.0231
Loa Loa (eye worm) transcription factor SMAD2 0.0255 0.2819 0.2813
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0229 0.1424
Echinococcus multilocularis lysyl tRNA synthetase 0.0025 0.0116 0.0108
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0181 0.195 0.3608
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0033 0.0216 0.1257
Loa Loa (eye worm) integrin beta-2 0.0544 0.6203 0.62
Echinococcus granulosus heat shock protein 0.0035 0.023 0.0223
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0818 0.9418 0.9418
Giardia lamblia Grp94/Hsp90 0.0028 0.0148 0.0898
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0748 0.1294
Loa Loa (eye worm) hypothetical protein 0.0035 0.0238 0.0231
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Brugia malayi hypothetical protein 0.0027 0.014 0.0132
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0033 0.0216 0.0209
Loa Loa (eye worm) hypothetical protein 0.0375 0.4222 0.4217
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0238 0.0231
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0229 0.1424
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0405 0.0398
Schistosoma mansoni endoplasmin 0.0035 0.023 0.023
Schistosoma mansoni microtubule-associated protein tau 0.0701 0.8048 0.8048
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Onchocerca volvulus 0.0079 0.0748 0.0741
Plasmodium vivax vivapain-3 0.0018 0.0037 0.0055
Onchocerca volvulus 0.002 0.0057 0.0049
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0229 0.0527
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0529 0.7035
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0235 0.0228
Giardia lamblia Heat shock protein HSP 90-alpha 0.0035 0.023 0.143
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Leishmania major cathepsin L-like protease 0.0135 0.1403 0.3312
Leishmania major hypothetical protein, conserved 0.0027 0.014 0.0314
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0529 0.7035
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0238 0.1479
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0543 0.0936
Onchocerca volvulus 0.0035 0.0238 0.0231
Toxoplasma gondii thioredoxin reductase 0.0047 0.0375 0.1043
Plasmodium vivax glutathione reductase, putative 0.0047 0.0375 0.0683
Plasmodium falciparum endoplasmin, putative 0.0021 0.0073 0.0122
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.1046 0.2464
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0148 0.0898
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0065 0.0057
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1403 0.3312
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Plasmodium vivax CDK-related protein kinase 6, putative 0.0475 0.5392 1
Schistosoma mansoni transcription factor LCR-F1 0.0187 0.2024 0.2024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0037 0.007
Plasmodium falciparum thioredoxin reductase 0.0016 0.0015 0.0013
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0072 0.0112
Onchocerca volvulus 0.0024 0.0101 0.0093
Mycobacterium tuberculosis Conserved protein 0.0079 0.0748 0.1294
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0.023 0.0529
Schistosoma mansoni integrin beta subunit 0.0432 0.4894 0.4894
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0065 0.0057
Brugia malayi MH2 domain containing protein 0.0017 0.0027 0.002
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0149 0.1567 0.156
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0405 0.0398
Schistosoma mansoni ero1-related 0.0054 0.0461 0.0461
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0015 0.0507
Schistosoma mansoni vesicular acetylcholine transporter 0.0867 1 1
Leishmania major glucose transporter, lmgt1 0.0035 0.0229 0.0527
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0065 0.0057
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0681 0.0674
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0007
Echinococcus multilocularis heat shock protein 0.0035 0.023 0.0223
Echinococcus multilocularis cathepsin L 0.0018 0.0037 0.003
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0543 0.0536
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Brugia malayi MH1 domain containing protein 0.0017 0.0027 0.002
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0072 0.0112
Giardia lamblia hypothetical protein 0.0024 0.0101 0.0599
Brugia malayi Cytochrome P450 family protein 0.002 0.0058 0.005
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0414 0.0414
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0142 0.0135
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0187 0.2024 0.2018
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0094
Treponema pallidum heat shock protein 90 0.0028 0.0148 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1082 0.1878
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0149 0.1567 0.1567
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0898 0.0892
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0529 0.091
Leishmania major glucose transporter, lmgt3 0.0035 0.0229 0.0527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Brugia malayi MH2 domain containing protein 0.0017 0.0027 0.002
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0042 0.022
Loa Loa (eye worm) hypothetical protein 0.0476 0.5411 0.5407
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0748 0.0748
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0042 0.0024
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0149 0.1567 0.1567
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0123 0.1266 0.2987
Toxoplasma gondii heat shock protein HSP90 0.0035 0.023 0.0632
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0229 0.0527
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0101 0.0094
Trypanosoma brucei protein kinase, putative 0.0104 0.1046 0.2464
Loa Loa (eye worm) sugar transporter 0.0112 0.1133 0.1126
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0748 0.475
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Onchocerca volvulus 0.0024 0.0101 0.0094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0898 0.0892
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0057 0.0049
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0015 0.0017
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0027 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0229 0.1424
Onchocerca volvulus 0.0035 0.0238 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.1133 0.7219
Entamoeba histolytica cysteine protease, putative 0.0035 0.0238 0.1012
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0033 0.0216 0.0209
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0149 0.1567 0.37
Brugia malayi MH2 domain containing protein 0.0255 0.2819 0.2813
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.014 0.0314
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0543 0.1271
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0057 0.0049
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0065 0.0065
Echinococcus granulosus calcium dependent protein kinase 0.0032 0.02 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Echinococcus granulosus fibrillin 1 0.0024 0.0101 0.0093
Brugia malayi nuclear receptor NHR-88 0.0021 0.0065 0.0057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Plasmodium vivax heat shock protein 86, putative 0.0035 0.023 0.0414
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0015 0.0017
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.023 0.0529
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0015 0.0046
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0033 0.0216 0.0216
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0748 0.1294
Echinococcus granulosus vesicular acetylcholine transporter 0.0867 1 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0065 0.0057
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0065 0.0057
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0238 0.1012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0898 0.0898
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Plasmodium falciparum protein kinase 6 0.0475 0.5392 1
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0235 0.0228
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0748 0.1757
Toxoplasma gondii facilitative glucose transporter GT1 0.0112 0.1133 0.3191
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0017
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0042 0.2448
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0149 0.1567 0.156
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0015 0.0013
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0748 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0065 0.0057
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0065 0.0065
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni Smad4 0.0017 0.0027 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0065 0.0057
Brugia malayi Smad1 0.0017 0.0027 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0748 0.0748
Echinococcus multilocularis calcium dependent protein kinase 0.0032 0.02 0.0192
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Echinococcus granulosus geminin 0.0526 0.5992 0.5989
Brugia malayi MAP kinase sur-1 0.0104 0.1046 0.1039
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Schistosoma mansoni ap endonuclease 0.0019 0.0042 0.0042
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0229 0.1424
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0015 0.0046
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0039 0.0281 0.0777
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0681 0.0674
Onchocerca volvulus 0.0079 0.0748 0.0741
Loa Loa (eye worm) hypothetical protein 0.0192 0.2071 0.2065
Giardia lamblia Tenascin-X 0.0024 0.0101 0.0599
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0015 0.0013
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0015 0.0017
Toxoplasma gondii cathepsin CPL 0.0035 0.0238 0.0654
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.014 0.0314
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Loa Loa (eye worm) fli-1 protein 0.0222 0.2427 0.2422
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Brugia malayi hypothetical protein 0.002 0.0057 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0963 0.0956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0748 0.1294
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0037 0.003
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.1046 0.6661
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0116 0.0116
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0235 0.0423
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.1081 0.1074
Echinococcus multilocularis General substrate transporter 0.0096 0.0949 0.0942
Plasmodium falciparum heat shock protein 90 0.0035 0.023 0.0414
Echinococcus granulosus lamin dm0 0.0027 0.0142 0.0135
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0073 0.0421
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0181 0.195 0.5509
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1082 0.1878
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0748 0.0741
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0235 0.0423
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0238 0.0428
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Toxoplasma gondii exonuclease III APE 0.0019 0.0042 0.0097
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.014 0.0314
Brugia malayi Cytochrome P450 family protein 0.002 0.0058 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0375 0.0368
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1403 0.3312
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.014 0.0375
Schistosoma mansoni survival motor neuron protein 0.0097 0.0963 0.0963
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0042 0.0081
Echinococcus multilocularis cysteine protease 0.0035 0.0238 0.0231
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0235 0.0646
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0116 0.0116
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.1046 0.2464
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.1046 0.1039
Schistosoma mansoni glucose transport protein 0.0112 0.1133 0.1133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0033 0.0216 0.0209
Brugia malayi beta-lactamase 0.0079 0.0748 0.0741
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0149 0.1567 1
Echinococcus multilocularis geminin 0.0526 0.5992 0.5989
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0748 0.1757
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0065 0.0057
Loa Loa (eye worm) CYP4Cod1 0.002 0.0058 0.005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0027 0.014 0.0132
Giardia lamblia Prolyl-tRNA synthetase 0.0033 0.0216 0.1339
Giardia lamblia Tenascin-37 0.0024 0.0101 0.0599
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Loa Loa (eye worm) endoplasmin 0.0035 0.023 0.0223
Trypanosoma brucei glucose transporter 1E 0.0035 0.0229 0.0527
Schistosoma mansoni ap endonuclease 0.0019 0.0042 0.0042
Brugia malayi Sugar transporter family protein 0.0112 0.1133 0.1126
Plasmodium falciparum hexose transporter 0.0112 0.1133 0.209
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.1403 0.3312
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.1223 1
Schistosoma mansoni lamin 0.0027 0.0142 0.0142
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0037 0.007
Echinococcus multilocularis survival motor neuron protein 1 0.0476 0.5411 0.5407
Echinococcus granulosus General substrate transporter 0.0096 0.0949 0.0942
Brugia malayi MH1 domain containing protein 0.0017 0.0027 0.002
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0037 0.0037
Schistosoma mansoni loxhd1 0.002 0.0057 0.0057
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0235 0.054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0108
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0065 0.0057
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0375 0.0368
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0057 0.0049
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0529 0.0521
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0229 0.0527
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0065 0.0065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0065 0.0057
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.023 0.0529
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0867 1 1
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0037 0.007
Giardia lamblia Tenascin precursor 0.0024 0.0101 0.0599
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0015 0.002
Brugia malayi Ets-domain containing protein 0.0073 0.0681 0.0674
Loa Loa (eye worm) hypothetical protein 0.0107 0.1081 0.1074
Echinococcus multilocularis heat shock protein 90 0.0028 0.0148 0.014
Loa Loa (eye worm) doublecortin family protein 0.002 0.0057 0.0049
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0057 0.0092
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0025 0.0116 0.0383
Toxoplasma gondii lysine-tRNA ligase 0.0025 0.0116 0.0307
Leishmania major trypanothione reductase 0.0047 0.0375 0.0873
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0229 0.0527
Schistosoma mansoni hypothetical protein 0.005 0.0405 0.0405
Entamoeba histolytica hypothetical protein 0.0187 0.2024 1
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0028 0.0148 0.066
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0027 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0037 0.003
Echinococcus multilocularis lamin 0.0027 0.0142 0.0135
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0112 0.1132 0.1125
Mycobacterium tuberculosis Conserved protein 0.0079 0.0748 0.1294
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0065 0.0057
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0543 0.0543
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0037 0.0189
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0112 0.1133 0.1126
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Echinococcus granulosus cathepsin l1 0.0035 0.0238 0.0231
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0015 0.0012
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0028 0.0148 0.0332
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.1046 0.6661
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0898 0.0898
Echinococcus multilocularis smad 0.0017 0.0027 0.002
Echinococcus multilocularis fibrillin 1 0.0024 0.0101 0.0093
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0495 0.0488
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0182 0.0175
Echinococcus granulosus Endoplasmic reticulum oxidoreductin 1 0.0054 0.0461 0.0454
Brugia malayi Cathepsin L-like precursor 0.0024 0.0101 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Plasmodium falciparum glutathione reductase 0.0016 0.0015 0.0013
Schistosoma mansoni hypothetical protein 0.0112 0.1133 0.1133
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.014 0.0246
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0235 0.0228
Trypanosoma brucei Heat shock protein 83, putative 0.0035 0.023 0.0529
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0037 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.1046 0.1039
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0065 0.0057
Trichomonas vaginalis heat shock protein, putative 0.0035 0.023 0.143
Echinococcus multilocularis musashi 0.0027 0.0142 0.0135
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0238 0.0547
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0235 0.0423
Trypanosoma brucei pol-associated gene 1 0.0054 0.0461 0.1077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0149 0.1567 0.7699
Schistosoma mansoni lipoxygenase 0.0056 0.0477 0.0477
Onchocerca volvulus 0.0035 0.0238 0.0231
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0748 0.475
Mycobacterium ulcerans beta-lactamase 0.0079 0.0748 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0238 0.1479
Entamoeba histolytica protein kinase, putative 0.0035 0.0235 0.0998
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0017 0.0009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0093
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0042 0.0081
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.1046 0.1039
Onchocerca volvulus 0.002 0.0057 0.0049
Plasmodium falciparum mitogen-activated protein kinase 2 0.0181 0.195 0.3608
Plasmodium falciparum endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.0843
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0065 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0042 0.022
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0375 0.0642
Echinococcus granulosus lysyl tRNA synthetase 0.0025 0.0116 0.0108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0238 0.0231
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0065 0.0065
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0015 0.0017
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0027 0.002
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0028 0.0148 1
Brugia malayi Cathepsin L-like precursor 0.0035 0.0238 0.0231
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0235 0.0646
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0037 0.0037
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0065 0.0057
Mycobacterium leprae Probable lipase LipE 0.0079 0.0748 0.5877
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0007
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0027 0.002
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0045 0.009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Loa Loa (eye worm) heat shock protein 90 0.0035 0.023 0.0223
Trypanosoma cruzi endoplasmic reticulum oxidoreductin, putative 0.0054 0.0461 0.1077
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0065 0.0057
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0028 0.0148 0.0245
Leishmania major cytochrome p450-like protein 0.002 0.0058 0.0119
Plasmodium vivax unspecified product 0.0018 0.0037 0.0055
Echinococcus multilocularis fibrillin 2 0.0024 0.0101 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0037 0.0055
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Echinococcus multilocularis protein jagged 2 0.0024 0.0101 0.0093
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0094
Brugia malayi beta-lactamase family protein 0.0079 0.0748 0.0741
Leishmania major cathepsin L-like protease 0.0135 0.1403 0.3312
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0405 0.0398
Brugia malayi ecdysteroid receptor 0.0021 0.0065 0.0057
Echinococcus granulosus GPCR family 2 0.005 0.0405 0.0398
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0142 0.0135
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0112 0.1133 0.1126
Loa Loa (eye worm) hypothetical protein 0.0079 0.0748 0.0741
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.014 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.1046 0.1046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Brugia malayi Kelch motif family protein 0.0112 0.1132 0.1125
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0235 0.0423
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0142 0.0135
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0238 0.0547
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0017 0.0009
Schistosoma mansoni hypothetical protein 0.0526 0.5992 0.5992
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0057
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.1403 0.3312
Schistosoma mansoni polycystin 1-related 0.002 0.0057 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0058 0.0119
Schistosoma mansoni smad1 5 8 and 0.0017 0.0027 0.0027
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0042 0.2045
Brugia malayi EGF-like domain containing protein 0.0024 0.0101 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0037 0.007
Chlamydia trachomatis lysine--tRNA ligase 0.0025 0.0116 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0543 0.0536
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0028 0.0148 0.014
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0015 0.0096
Giardia lamblia High cysteine protein 0.0024 0.0101 0.0599
Trypanosoma brucei glucose transporter, putative 0.0035 0.0229 0.0527
Echinococcus multilocularis tumor protein p63 0.0344 0.3857 0.3852
Echinococcus granulosus intermediate filament protein 0.0027 0.0142 0.0135
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0065 0.0065
Schistosoma mansoni heat shock protein 0.0035 0.023 0.023
Schistosoma mansoni gabp alpha 0.0073 0.0681 0.0681
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0748 0.1294
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Trypanosoma brucei heat shock protein, putative 0.0035 0.023 0.0529
Echinococcus granulosus adam 0.0024 0.0101 0.0093
Echinococcus granulosus survival motor neuron protein 1 0.0476 0.5411 0.5407
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.014 0.0246
Trypanosoma cruzi heat shock protein 85, putative 0.0028 0.0148 0.0332
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0529 0.1477
Leishmania major C-8 sterol isomerase-like protein 0.0375 0.4222 1
Echinococcus granulosus cysteine protease 0.0018 0.0037 0.003
Echinococcus granulosus ubiquitin specific protease 41 0.0149 0.1567 0.156
Onchocerca volvulus 0.0035 0.0238 0.0231
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.1046 0.2464
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0101 0.0322
Schistosoma mansoni sugar transporter 0.0016 0.0007 0.0007
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0033 0.0216 0.0902
Entamoeba histolytica hypothetical protein 0.0025 0.0116 0.0396
Schistosoma mansoni hypothetical protein 0.0187 0.2024 0.2024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0238 0.1479
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0238 0.1479
Echinococcus multilocularis microtubule associated protein 2 0.0701 0.8048 0.8047
Loa Loa (eye worm) hypothetical protein 0.0112 0.1132 0.1125
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0058 0.005
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0235 0.0423
Schistosoma mansoni ets-related 0.0222 0.2427 0.2427
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0015 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.1223 0.2123
Onchocerca volvulus 0.005 0.0414 0.0407
Leishmania major cathepsin L-like protease 0.0035 0.0238 0.0547
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0238 0.1012
Brugia malayi lysyl-tRNA synthetase 0.0025 0.0116 0.0108
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Leishmania major heat shock protein 83-1 0.0035 0.023 0.0529
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0007 0.0007
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.1663 0.1657
Brugia malayi Thioredoxin reductase 0.0047 0.0375 0.0368
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0281 0.065
Trypanosoma brucei trypanothione reductase 0.0047 0.0375 0.0873
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0065 0.0057
Loa Loa (eye worm) glutathione reductase 0.0047 0.0375 0.0368
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0065 0.0057
Loa Loa (eye worm) hypothetical protein 0.0157 0.1663 0.1657
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0027 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0065 0.0057
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0529 0.0529
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0015 0.002
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0681 0.0674
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0065 0.0057
Giardia lamblia Lysyl-tRNA synthetase 0.0025 0.0116 0.0694
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0116 0.1461
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0065 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0058 0.0119
Loa Loa (eye worm) hypothetical protein 0.005 0.0405 0.0398
Echinococcus multilocularis adam 0.0024 0.0101 0.0093
Trypanosoma brucei glucose transporter 2A 0.0035 0.0229 0.0527
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0065 0.0057
Echinococcus granulosus lamin 0.0027 0.0142 0.0135

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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