Detailed information for compound 805795

Basic information

Technical information
  • TDR Targets ID: 805795
  • Name: 3-methyl-4-oxo-N-propan-2-ylphthalazine-1-car boxamide
  • MW: 245.277 | Formula: C13H15N3O2
  • H donors: 1 H acceptors: 2 LogP: 1.38 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(NC(=O)c1nn(C)c(=O)c2c1cccc2)C
  • InChi: 1S/C13H15N3O2/c1-8(2)14-12(17)11-9-6-4-5-7-10(9)13(18)16(3)15-11/h4-8H,1-3H3,(H,14,17)
  • InChiKey: UPAKEYCYLNWGKI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-isopropyl-3-methyl-4-oxo-phthalazine-1-carboxamide
  • N-isopropyl-3-methyl-4-oxo-1-phthalazinecarboxamide
  • N-isopropyl-4-keto-3-methyl-phthalazine-1-carboxamide
  • 3-methyl-4-oxo-N-propan-2-yl-phthalazine-1-carboxamide
  • A3477/0147469
  • ZINC01422672
  • Phthalazine-1-carboxylic acid, 3-methyl-4-oxo-3,4-dihydro-, isopropylamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tumor protein p63 0.0662 0.1328 0.1328
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0067 0.0105 0.3175
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0128 0.1945
Loa Loa (eye worm) hypothetical protein 0.0052 0.0074 0.0189
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0013 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0013 0.0081
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0032
Schistosoma mansoni sulfide quinone reductase 0.0018 0.0005 0.0005
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0017 0.0017
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0055 0.0082 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0017 0.012
Brugia malayi jmjC domain containing protein 0.0032 0.0033 0.0084
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0058 0.0897
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0052 0.0052
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0013 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.005 0.045
Loa Loa (eye worm) hypothetical protein 0.0032 0.0033 0.0084
Brugia malayi hypothetical protein 0.0021 0.0012 0.0031
Leishmania major hypothetical protein, conserved 0.0028 0.0026 0.0364
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0073 0.0709
Schistosoma mansoni amine GPCR 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Echinococcus granulosus somatostatin receptor 0.0077 0.0127 0.0127
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0013 0.0136
Loa Loa (eye worm) hypothetical protein 0.007 0.0112 0.0285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0028 0.0237
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0033 0.0033
Schistosoma mansoni opsin-like receptor 0.0077 0.0127 0.0127
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0077 0.0127 0.0127
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.004 0.0589
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0074 0.012 0.3629
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0008 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0102 0.0102
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0539 0.1076 0.2735
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0043 0.038
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0327 0.0641 0.163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Schistosoma mansoni alpha-1 adrenergic receptor 0.0077 0.0127 0.0127
Plasmodium falciparum thioredoxin reductase 0.0067 0.0105 0.1584
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0052 0.0052
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0077 0.0127 0.0127
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0013 0.0255
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0058 0.2909
Schistosoma mansoni hypothetical protein 0.0018 0.0005 0.0005
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0096 0.0096
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0018 0.0005 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0037
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0052 0.0052
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0052 0.0052
Schistosoma mansoni sodium/chloride dependent transporter 0.0327 0.0641 0.0641
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0077 0.0127 0.0127
Brugia malayi beta-lactamase family protein 0.007 0.0112 0.0285
Schistosoma mansoni hypothetical protein 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.1929 0.3934 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0489 0.0973 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.007 0.0112 0.0285
Schistosoma mansoni jumonji/arid domain-containing protein 0.0123 0.0221 0.0221
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0033 0.0033
Brugia malayi Inositol-1 0.0036 0.0043 0.0109
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0073 0.0709
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0052 0.012
Schistosoma mansoni glutamate synthase 0.0018 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0096 0.2875
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0071 0.1119
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0067 0.0105 0.17
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0071 0.0663
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0067 0.0105 0.3175
Trichomonas vaginalis set domain proteins, putative 0.0505 0.1007 1
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0013 0.0032
Schistosoma mansoni hypothetical protein 0.0103 0.018 0.018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0077 0.0127 0.0127
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0057 0.0878
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0013 0.0255
Loa Loa (eye worm) thioredoxin reductase 0.0193 0.0364 0.0926
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0071 0.1043
Brugia malayi Melatonin receptor type 1A 0.0077 0.0127 0.0324
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0071 0.1119
Brugia malayi glutamate synthase 0.0018 0.0005 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Onchocerca volvulus 0.0077 0.0127 0.0312
Mycobacterium leprae Probable lipase LipE 0.007 0.0112 0.111
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Brugia malayi glutathione reductase 0.0193 0.0364 0.0926
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0008 0.0008
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0043 0.2082
Schistosoma mansoni inositol monophosphatase 0.0036 0.0043 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0017 0.0017
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0067 0.0105 0.17
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Brugia malayi neuropeptide F receptor 0.0077 0.0127 0.0324
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0075 0.073
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0077 0.0127 0.0127
Echinococcus multilocularis neuropeptide s receptor 0.0077 0.0127 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0052 0.0131
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0077 0.0127 0.0127
Echinococcus multilocularis microtubule associated protein 2 0.488 1 1
Brugia malayi G-protein coupled receptor 0.0077 0.0127 0.0324
Onchocerca volvulus 0.0019 0.0008 0.0007
Brugia malayi MAP kinase sur-1 0.005 0.0071 0.0181
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0018 0.0005 0.0005
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0018 0.0005 0.0005
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0013 0.0136
Mycobacterium ulcerans hypothetical protein 0.0161 0.03 0.9295
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0067 0.0105 0.8145
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0266 0.4409
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0067 0.0105 0.0268
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0033 0.0033
Schistosoma mansoni disulfide oxidoreductase 0.0018 0.0005 0.0005
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0011 0.0101
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0327 0.0641 0.0641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0017 0.0119
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0013 0.0084
Echinococcus granulosus allatostatin A receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0302
Brugia malayi beta-lactamase 0.007 0.0112 0.0285
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0043 0.038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0013 0.0032
Loa Loa (eye worm) programmed cell death 8 0.0018 0.0005 0.0012
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0077 0.0127 0.0127
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0008 0.0007
Giardia lamblia GTOR 0.0044 0.0058 0.5278
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0052 0.0131
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0033 0.0033
Leishmania major hypothetical protein, conserved 0.007 0.0112 0.1812
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.0598 1
Onchocerca volvulus 0.0077 0.0127 0.0312
Schistosoma mansoni growth hormone secretagogue receptor 0.0077 0.0127 0.0127
Brugia malayi jmjC domain containing protein 0.0032 0.0033 0.0084
Toxoplasma gondii hypothetical protein 0.0327 0.0641 1
Onchocerca volvulus 0.0077 0.0127 0.0312
Schistosoma mansoni inositol monophosphatase 0.0036 0.0043 0.0043
Echinococcus granulosus neuropeptide s receptor 0.0077 0.0127 0.0127
Onchocerca volvulus 0.0019 0.0008 0.0007
Brugia malayi MH2 domain containing protein 0.0116 0.0206 0.0524
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0043 0.0599
Schistosoma mansoni biogenic amine receptor 0.0077 0.0127 0.0127
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.005 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0077 0.0127 0.0324
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0489 0.0973 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0077 0.0127 0.0127
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0023 0.0194
Schistosoma mansoni glutamate synthase 0.0018 0.0005 0.0005
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0447 0.0888 0.9121
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0112 0.1812
Mycobacterium tuberculosis Conserved protein 0.007 0.0112 0.111
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0058 0.0531
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.005 0.076
Brugia malayi Dopamine receptor protein 1 0.0077 0.0127 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0017 0.0119
Echinococcus granulosus g-protein coupled receptor 0.0077 0.0127 0.0127
Plasmodium falciparum glutathione reductase 0.0067 0.0105 0.1584
Brugia malayi beta-lactamase family protein 0.007 0.0112 0.0285
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0058 0.0897
Echinococcus multilocularis serotonin receptor 0.0077 0.0127 0.0127
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0067 0.0105 0.1584
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0012 0.0012
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0128 0.0128
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0071 0.1119
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0071 0.0181
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0112 0.0285
Echinococcus multilocularis fmrfamide receptor 0.0077 0.0127 0.0127
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0075 0.073
Schistosoma mansoni cpg binding protein 0.0091 0.0156 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.03 0.3049
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Onchocerca volvulus 0.0077 0.0127 0.0312
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0071 0.1119
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0206 0.0524
Echinococcus multilocularis cpg binding protein 0.0091 0.0156 0.0156
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0077 0.0127 0.0127
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0012
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0036 0.0043 0.0043
Echinococcus multilocularis protein dispatched 1 0.0048 0.0067 0.0067
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0188 0.0188
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0823 0.1659 0.1659
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.012 0.6297
Schistosoma mansoni opsin-like receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0172 0.0322 1
Brugia malayi ORL1-like opioid receptor 0.0077 0.0127 0.0324
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Echinococcus granulosus dro:myosuppressin receptor 0.0077 0.0127 0.0127
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.044 0.0872 0.8958
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0302
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Echinococcus multilocularis tumor protein p63 0.0662 0.1328 0.1328
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.012 0.1943
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0033 0.0084
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0067 0.0105 0.1042
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0058 0.0897
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0013 0.0084
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0013 0.0136
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0052 0.012
Trypanosoma cruzi trypanothione reductase, putative 0.0193 0.0364 0.6065
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Mycobacterium tuberculosis Probable reductase 0.044 0.0872 0.8958
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0052 0.0131
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0128 0.1945
Brugia malayi putative neuropeptide receptor 0.0077 0.0127 0.0324
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0008 0.0008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0167 0.0425
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0055 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.0077 0.0127 0.0127
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.005 0.2463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0058 0.0531
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0067 0.0105 0.1584
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0052 0.0052
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0071 0.1119
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0073 0.0073
Toxoplasma gondii hypothetical protein 0.0049 0.007 0.1023
Echinococcus multilocularis G-protein coupled receptor, putative 0.0077 0.0127 0.0127
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0033 0.0479
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus fmrfamide receptor 0.0077 0.0127 0.0127
Schistosoma mansoni cpg binding protein 0.0091 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0074 0.012 0.0305
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Brugia malayi Serotonin receptor 0.0077 0.0127 0.0324
Echinococcus multilocularis geminin 0.0166 0.031 0.031
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0172 0.0322 0.0819
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0082 0.0794
Echinococcus granulosus glutamate synthase 0.0018 0.0005 0.0005
Schistosoma mansoni glutamate synthase 0.0018 0.0005 0.0005
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0058 0.0897
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0067 0.0105 0.17
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0112 0.1812
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.012 0.119
Echinococcus multilocularis G protein coupled receptor 139 0.0077 0.0127 0.0127
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0028 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0017 0.012
Schistosoma mansoni hypothetical protein 0.0041 0.0052 0.0052
Echinococcus multilocularis neuropeptide FF receptor 2 0.0077 0.0127 0.0127
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0033 0.0033
Trypanosoma brucei RNA helicase, putative 0.0103 0.018 0.2961
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0118 0.0211 0.0211
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0028 0.0071
Onchocerca volvulus 0.0022 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0041 0.0052 0.0052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0058 0.0147
Mycobacterium ulcerans lipase LipD 0.007 0.0112 0.3384
Plasmodium vivax amine transporter, putative 0.0327 0.0641 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Mycobacterium ulcerans beta-lactamase 0.007 0.0112 0.3384
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0327 0.0641 0.0641
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0037 0.0094
Schistosoma mansoni survival motor neuron protein 0.0097 0.0167 0.0167
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0077 0.0127 0.0324
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.004 0.0589
Echinococcus multilocularis serotonin transporter 0.1929 0.3934 0.3934
Brugia malayi Pre-SET motif family protein 0.0444 0.0881 0.224
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0128 0.0128
Schistosoma mansoni sodium/chloride dependent transporter 0.0328 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0013 0.0084
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0206 0.0524
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0096 0.1434
Onchocerca volvulus 0.007 0.0112 0.0274
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0172 0.0322 0.0322
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0008 0.0019
Trypanosoma brucei trypanothione reductase 0.0193 0.0364 0.6065
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0077 0.0127 0.0127
Echinococcus multilocularis somatostatin receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0077 0.0127 0.0127
Brugia malayi Tachykinin-like peptides receptor 99D 0.0077 0.0127 0.0324
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus g protein coupled receptor 0.0077 0.0127 0.0127
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0074 0.012 0.0305
Schistosoma mansoni neuropeptide F-like receptor 0.0077 0.0127 0.0127
Brugia malayi hypothetical protein 0.0019 0.0008 0.0019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0026 0.0339
Loa Loa (eye worm) hypothetical protein 0.0327 0.0641 0.163
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0052 0.0131
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0077 0.0127 0.0324
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0172 0.0322 0.328
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0077 0.0127 0.0127
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0188 0.0188
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0067 0.0105 0.1584
Schistosoma mansoni neuropeptide receptor 0.0077 0.0127 0.0127
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0033 0.0479
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0052 0.0131
Echinococcus granulosus neuropeptide Y receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0052 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0052 0.0131
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0327 0.0641 0.0641
Echinococcus multilocularis neuropeptide receptor 0.0077 0.0127 0.0127
Onchocerca volvulus 0.0022 0.0013 0.0021
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0052 0.0052
Onchocerca volvulus 0.1929 0.3934 1
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0055 0.0055
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.005 0.4469
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0052 0.0052
Brugia malayi CXXC zinc finger family protein 0.0086 0.0145 0.037
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.0097 0.0167 0.0425
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0172 0.0322 0.0322
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0067 0.0105 0.1584
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0327 0.0641 0.0641
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0118 0.0211 0.0211
Onchocerca volvulus 0.0074 0.012 0.0293
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0013 0.0255
Plasmodium vivax hypothetical protein, conserved 0.007 0.0112 0.1688
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Mycobacterium tuberculosis Probable oxidoreductase 0.0489 0.0973 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0077 0.0127 0.0127
Echinococcus multilocularis neuropeptide Y receptor 0.0077 0.0127 0.0127
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0033 0.0033
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.012 0.3629
Loa Loa (eye worm) hypothetical protein 0.0065 0.0102 0.026
Echinococcus granulosus g protein coupled receptor 0.0077 0.0127 0.0127
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0018 0.0005 0.0005
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0128 0.1945
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0017 0.012
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0018 0.0005 0.0005
Brugia malayi putative neuropeptide receptor NPR1 0.0077 0.0127 0.0324
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0112 0.111
Echinococcus multilocularis dnaJ subfamily B 0.1228 0.2493 0.2493
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0067 0.0105 0.17
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0013 0.0032
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0076 0.1205
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi RE15519p 0.0077 0.0127 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0171
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0052 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0021 0.0166
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus biogenic amine 5HT receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0077 0.0127 0.0127
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0043 0.0642
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.005 0.076
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0074 0.012 0.119
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0069 0.0175
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0037
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Loa Loa (eye worm) glutathione reductase 0.0193 0.0364 0.0926
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0018 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0032 0.0033 0.0084
Trypanosoma brucei protein kinase, putative 0.005 0.0071 0.1119
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0008 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.0598 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0008 0.0037
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0026 0.0364
Loa Loa (eye worm) neuropeptide F receptor 0.0077 0.0127 0.0324
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0327 0.0641 1
Mycobacterium ulcerans hypothetical protein 0.007 0.0112 0.3384
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0096 0.2875
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0052 0.012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0077 0.0127 0.0127
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0013 0.0255
Echinococcus granulosus hypothetical protein 0.0077 0.0127 0.0127
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0077 0.0127 0.0127
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0327 0.0641 1
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0052 0.0052
Brugia malayi AKH receptor 0.0077 0.0127 0.0324
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0112 0.1073
Toxoplasma gondii hypothetical protein 0.0027 0.0023 0.0295
Schistosoma mansoni hypothetical protein 0.0097 0.0167 0.0167
Treponema pallidum NADH oxidase 0.0067 0.0105 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0071 0.0071
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0266 0.4409
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0052 0.0052
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0013 0.0084
Brugia malayi G-protein coupled receptor 0.0077 0.0127 0.0324
Plasmodium falciparum glutathione reductase 0.0193 0.0364 0.5651
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.0943 0.0943
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0052 0.0131
Brugia malayi hypothetical protein 0.0474 0.0943 0.2397
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0013 0.0127
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0327 0.0641 0.163
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0018 0.0005 0.0012
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0013 0.0136
Brugia malayi hypothetical protein 0.0021 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0049 0.0069 0.0175
Loa Loa (eye worm) hypothetical protein 0.1929 0.3934 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0008 0.0037
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0023 0.0295
Leishmania major hypothetical protein, conserved 0.0032 0.0033 0.0479
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0052 0.0131
Echinococcus multilocularis g-protein coupled receptor 0.0077 0.0127 0.0127
Schistosoma mansoni sodium/chloride dependent transporter 0.1929 0.3934 0.3934
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0074 0.012 0.119
Loa Loa (eye worm) hypothetical protein 0.0032 0.0033 0.0084
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0071 0.0071
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0128 0.0315
Schistosoma mansoni neuropeptide receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0045 0.04
Echinococcus multilocularis neuropeptide receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.017 0.0432
Loa Loa (eye worm) hypothetical protein 0.1929 0.3934 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0327 0.0641 0.163
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Echinococcus granulosus serotonin transporter 0.1929 0.3934 0.3934
Brugia malayi nuclear hormone receptor 0.0041 0.0052 0.0131
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0026 0.0339
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0077 0.0127 0.0127
Echinococcus granulosus neuropeptide receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Echinococcus multilocularis neuropeptides capa receptor 0.0077 0.0127 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0052 0.0131
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1929 0.3934 0.3934
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0033 0.0446
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0033 0.0446
Schistosoma mansoni cpg binding protein 0.0086 0.0145 0.0145
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0036 0.0043 0.0043
Echinococcus granulosus sodium and chloride dependent glycine 0.0327 0.0641 0.0641
Echinococcus multilocularis expressed conserved protein 0.0092 0.0158 0.0158
Schistosoma mansoni microtubule-associated protein tau 0.488 1 1
Brugia malayi hypothetical protein 0.0019 0.0008 0.0019
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.005 0.005
Onchocerca volvulus 0.0327 0.0641 0.1621
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0008 0.0008
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0071 0.0663
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0052 0.0052
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0008 0.0008
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.017 0.9034
Loa Loa (eye worm) serotonin transporter b 0.1929 0.3934 1
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0013 0.0084
Toxoplasma gondii thioredoxin reductase 0.0193 0.0364 0.5651
Schistosoma mansoni nuclear receptor 0.0019 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Brugia malayi sulfakinin receptor protein 0.0077 0.0127 0.0324
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0077 0.0127 0.0127
Echinococcus granulosus alpha 1A adrenergic receptor 0.0077 0.0127 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0021 0.0166
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0474 0.0943 0.2397
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0071 0.1119
Echinococcus multilocularis serotonin receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0128 0.0128
Loa Loa (eye worm) melatonin receptor type 1A 0.0077 0.0127 0.0324
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0013 0.0255
Schistosoma mansoni biogenic amine (5HT) receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0171
Echinococcus granulosus 7tm_1 domain containing protein 0.0077 0.0127 0.0127
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0052 0.0052
Brugia malayi GnHR receptor homolog 0.0077 0.0127 0.0324
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0172 0.0322 0.5354
Entamoeba histolytica hypothetical protein 0.0107 0.0188 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0082 0.0207
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0067 0.0105 0.0105
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0112 0.0285
Toxoplasma gondii histone lysine methyltransferase SET1 0.0166 0.0309 0.4778
Schistosoma mansoni zinc finger protein 0.0019 0.0008 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0037
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0077 0.0127 0.0324
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0013 0.0084
Onchocerca volvulus 0.0077 0.0127 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Brugia malayi steroid hormone receptor 0.0041 0.0052 0.0131
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0026 0.0364
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0043 0.3077
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0071 0.0663
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.012 0.6297
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0102 0.1536
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0094
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Onchocerca volvulus 0.0077 0.0127 0.0312
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0008 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0007 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0302
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0082 0.1208
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.044 0.0872 0.8958
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0035 0.0313
Brugia malayi Serotonin receptor 0.0077 0.0127 0.0324
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0096 0.0096
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus cpg binding protein 0.0091 0.0156 0.0156
Onchocerca volvulus 0.0077 0.0127 0.0312
Echinococcus granulosus phd:f box containing protein 0.0032 0.0033 0.0033
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0058 0.0058
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.007 0.0112 0.0285
Schistosoma mansoni adenoreceptor 0.0077 0.0127 0.0127
Onchocerca volvulus 0.0077 0.0127 0.0312
Echinococcus multilocularis sodium and chloride dependent glycine 0.0327 0.0641 0.0641
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0052 0.0052
Echinococcus multilocularis fmrfamide receptor 0.0077 0.0127 0.0127
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0057 0.0878
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.005 0.005
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0032 0.0033 0.0084
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0026 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.004 0.0348
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0489 0.0973 1
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0052 0.0052
Echinococcus granulosus neuropeptides capa receptor 0.0077 0.0127 0.0127
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0052 0.0052
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.012 0.119
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0067 0.0105 0.0105
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0008 0.0008
Onchocerca volvulus 0.0022 0.0013 0.0021
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0096 0.0943
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Trichomonas vaginalis glutathione reductase, putative 0.0067 0.0105 0.1007
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0035 0.0475
Onchocerca volvulus 0.0327 0.0641 0.1621
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0102 0.0102
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0008 0.0019
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0077 0.0127 0.0127
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0075 0.073
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0043 0.12
Schistosoma mansoni patched 1 0.0042 0.0055 0.0055
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0043 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0302
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0052 0.0131
Echinococcus multilocularis sex peptide receptor 0.0077 0.0127 0.0127
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0033 0.0033
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0067 0.0105 0.3175
Brugia malayi hypothetical protein 0.0018 0.0006 0.0014
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0018 0.0005 0.0005
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0074 0.012 0.3629
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0167 0.0167
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.0221 0.0563
Echinococcus granulosus peptide allatostatin:somatostatin 0.0077 0.0127 0.0127
Brugia malayi hypothetical protein 0.0327 0.0641 0.163
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0112 0.111
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0161 0.0298 0.0759
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0033 0.0033
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0012 0.0012
Schistosoma mansoni neuropeptide f receptor 76f 0.0077 0.0127 0.0127
Echinococcus multilocularis neuropeptides capa receptor 0.0077 0.0127 0.0127
Toxoplasma gondii hypothetical protein 0.0327 0.0641 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0058 0.0897
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0052 0.0052
Schistosoma mansoni jumonji/arid domain-containing protein 0.0123 0.0221 0.0221
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0013 0.0032
Brugia malayi ecdysone receptor 0.0019 0.0008 0.0019
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0112 0.1812
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0005 0.0014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0102 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0052 0.0131
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0058 0.2909
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Entamoeba histolytica acyl-coA synthetase, putative 0.0074 0.012 0.6297
Loa Loa (eye worm) hypothetical protein 0.0098 0.017 0.0432
Echinococcus granulosus neuropeptide receptor A26 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Schistosoma mansoni amine GPCR 0.0077 0.0127 0.0127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Brugia malayi hypothetical protein 0.0107 0.0188 0.0477
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0193 0.0364 0.3716
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0077 0.0127 0.0324
Brugia malayi Pre-SET motif family protein 0.0065 0.0102 0.026
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0096 0.1539
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0052 0.0131
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Echinococcus granulosus biogenic amine 5HT receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0127 0.0127
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0013 0.0084
Schistosoma mansoni biogenic amine receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis protein patched 0.0042 0.0055 0.0055
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0052 0.0131
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0043 0.0642
Echinococcus granulosus dnaJ subfamily B 0.1228 0.2493 0.2493
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.0349 0.0349
Echinococcus multilocularis g protein coupled receptor 0.0077 0.0127 0.0127
Brugia malayi tailless protein 0.0019 0.0008 0.0019
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0071 0.1119
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0077 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.1228 0.2493 0.2493
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0013 0.0255
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0128 1
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0018 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Onchocerca volvulus 0.0077 0.0127 0.0312
Brugia malayi ecdysteroid receptor 0.0041 0.0052 0.0131
Onchocerca volvulus 0.007 0.0112 0.0274
Echinococcus granulosus lysine specific demethylase 5A 0.0123 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Loa Loa (eye worm) hypothetical protein 0.0055 0.0082 0.0207
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0071 0.0663
Schistosoma mansoni coup transcription factor 0.0041 0.0052 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Leishmania major trypanothione reductase 0.0193 0.0364 0.6065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0077 0.0127 0.0312
Onchocerca volvulus 0.0065 0.0102 0.0249
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0052 0.0052
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0327 0.0641 0.163
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0107 0.0188 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Schistosoma mansoni biogenic amine receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis allatostatin A receptor 0.0077 0.0127 0.0127
Leishmania major mitochondrial DNA polymerase beta 0.0306 0.0598 1
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0012 0.0031
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0012 0.0031
Schistosoma mansoni hypothetical protein 0.0166 0.031 0.031
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.044 0.0872 0.8958
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0327 0.0641 0.163
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0112 0.1073
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0013 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0077 0.0127 0.0127
Echinococcus granulosus tm gpcr rhodopsin 0.0077 0.0127 0.0127
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0017 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.0077 0.0127 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0013 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0033 0.0084
Onchocerca volvulus 0.0505 0.1007 0.2551
Echinococcus granulosus g protein coupled receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Echinococcus granulosus neuropeptide receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Treponema pallidum sodium- and chloride- dependent transporter 0.1929 0.3934 1
Schistosoma mansoni hypothetical protein 0.0077 0.0127 0.0127
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0327 0.0641 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0102 0.0102
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0074 0.012 0.0305
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0058 0.0058
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0128 0.3899
Echinococcus granulosus tachykinin peptides receptor 99D 0.0077 0.0127 0.0127
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.0257 0.0257
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0013 0.0255
Brugia malayi follicle stimulating hormone receptor 0.0539 0.1076 0.2735
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0043 0.0642
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0067
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0112 0.1073
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0327 0.0641 0.0641
Brugia malayi larval opioid receptor 0.0077 0.0127 0.0324
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.005 0.005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0067 0.0105 0.0105
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0008 0.0019
Plasmodium vivax glutathione reductase, putative 0.0193 0.0364 0.5651
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.012 0.3629
Brugia malayi nuclear hormone receptor 0.0019 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0077 0.0127 0.0127
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0013 0.0013
Brugia malayi hypothetical protein 0.0028 0.0026 0.0067
Loa Loa (eye worm) hypothetical protein 0.007 0.0112 0.0285
Schistosoma mansoni hypothetical protein 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Plasmodium vivax SET domain protein, putative 0.0065 0.0102 0.1536
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0171
Brugia malayi nuclear receptor RXR 0.0021 0.0012 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.004 0.0348
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0173 0.0173
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0077 0.0127 0.0324
Loa Loa (eye worm) oxidoreductase 0.0022 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0017 0.0017
Echinococcus multilocularis g protein coupled receptor 0.0077 0.0127 0.0127
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0071 0.6584
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) G-protein coupled receptor 0.0077 0.0127 0.0324
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0018 0.0005 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0096 0.0096
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0052 0.0131
Schistosoma mansoni histamine h1 receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0327 0.0641 0.163
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Echinococcus granulosus neuropeptides capa receptor 0.0077 0.0127 0.0127
Schistosoma mansoni myosin xvIII 0.0077 0.0127 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0074 0.012 0.0305
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0077 0.0127 0.0127
Onchocerca volvulus 0.0097 0.0167 0.0413
Brugia malayi G protein-coupled receptor 0.0077 0.0127 0.0324
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0071 0.0071
Onchocerca volvulus 0.0033 0.0037 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0037
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0057 0.0878
Trichomonas vaginalis mercuric reductase, putative 0.0067 0.0105 0.1007
Loa Loa (eye worm) DR-78 0.0019 0.0008 0.0019
Plasmodium falciparum thioredoxin reductase 0.0193 0.0364 0.5651
Loa Loa (eye worm) hypothetical protein 0.004 0.005 0.0126
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Schistosoma mansoni amine GPCR 0.0077 0.0127 0.0127
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.005 0.005
Onchocerca volvulus 0.0077 0.0127 0.0312
Loa Loa (eye worm) hypothetical protein 0.0327 0.0641 0.163
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.0943 0.0943
Onchocerca volvulus 0.0077 0.0127 0.0312
Loa Loa (eye worm) hypothetical protein 0.0078 0.0128 0.0327
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.017 0.017
Onchocerca volvulus 0.0086 0.0145 0.0358
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0112 0.111
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0327 0.0641 0.163
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0052 0.0052
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0112 0.111
Trichomonas vaginalis helicase, putative 0.002 0.0008 0.0037
Brugia malayi CHE-14 protein 0.0042 0.0055 0.0139
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0033 0.0033
Schistosoma mansoni sulfide quinone reductase 0.0018 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.004 0.005 0.045
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0012 0.0031
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1929 0.3934 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0128 0.1945
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0112 0.1073
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0013 0.0136
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0128 0.3899
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0052 0.0131
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0013 0.0255
Loa Loa (eye worm) hypothetical protein 0.0074 0.012 0.0305
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0033 0.0033
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0112 0.0112
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0052 0.0131
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0071 0.0071
Schistosoma mansoni neuropeptide receptor 0.0077 0.0127 0.0127
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0058 0.0897
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0327 0.0641 0.0641
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0052 0.0131
Loa Loa (eye worm) hypothetical protein 0.0055 0.0082 0.0207
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0058 0.0058
Loa Loa (eye worm) neuropeptide F receptor 0.0077 0.0127 0.0324
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0112 0.0112
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.012 0.3629
Echinococcus granulosus neuropeptide FF receptor 2 0.0077 0.0127 0.0127
Brugia malayi jmjC domain containing protein 0.0118 0.0211 0.0537
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0018 0.0005 0.0005
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0067 0.0105 0.17
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0128 0.1279
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0073 0.0709
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0112 0.3384
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0052 0.0131
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0082 0.2421
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0043 0.0043
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0049 0.0069 0.0175
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0013 0.0136
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0327 0.0641 0.163
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0172 0.0322 0.0322
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0327 0.0641 0.0641
Onchocerca volvulus 0.0097 0.0167 0.0414
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Echinococcus granulosus sodium and chloride dependent glycine 0.0327 0.0641 0.0641
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0067 0.0105 0.17
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0018 0.0005 0.0012
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.017 0.017
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0013 0.0032
Echinococcus multilocularis sodium and chloride dependent glycine 0.0327 0.0641 0.0641
Brugia malayi jmjC domain containing protein 0.0123 0.0221 0.0563
Toxoplasma gondii NADPH-glutathione reductase 0.0067 0.0105 0.1584
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0013 0.0136
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0096 0.0096
Schistosoma mansoni opsin-like receptor 0.0077 0.0127 0.0127
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0026 0.0339
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0017 0.0017
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0102 0.0102
Entamoeba histolytica hypothetical protein 0.0107 0.0188 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0128 0.1945
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0013 0.0127
Onchocerca volvulus 0.007 0.0112 0.0274
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0023 0.0295
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0306 0.0598 1
Loa Loa (eye worm) hypothetical protein 0.0327 0.0641 0.163
Brugia malayi Thioredoxin reductase 0.0193 0.0364 0.0926
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi AMP-binding enzyme family protein 0.0074 0.012 0.0305
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0052 0.0052
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.007 0.0112 0.0285
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0102 0.0102
Brugia malayi nuclear receptor NHR-88 0.0041 0.0052 0.0131
Onchocerca volvulus Neuropeptide F receptor homolog 0.0077 0.0127 0.0312
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.044 0.0872 0.8958
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0145 0.037
Brugia malayi neuropeptide F receptor 0.0077 0.0127 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0017 0.012
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0037
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.0082 0.1208
Loa Loa (eye worm) G-protein coupled receptor 0.0077 0.0127 0.0324
Brugia malayi jmjC domain containing protein 0.0032 0.0033 0.0084
Brugia malayi Dopamine receptor 0.0077 0.0127 0.0324
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0013 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0052 0.0131
Giardia lamblia NADH oxidase lateral transfer candidate 0.0067 0.0105 1
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0052 0.0052
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0013 0.0032
Plasmodium falciparum amino acid transporter, putative 0.0327 0.0641 1
Brugia malayi nuclear receptor NHR-67 0.0019 0.0008 0.0019
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0013 0.0081
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0069 0.0175
Echinococcus multilocularis neuropeptide receptor A26 0.0077 0.0127 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0013 0.0032
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0028 0.0028
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0013 0.0013
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Schistosoma mansoni hypothetical protein 0.0077 0.0127 0.0127
Schistosoma mansoni biogenic amine (5HT) receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Echinococcus granulosus geminin 0.0166 0.031 0.031
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0033 0.0446
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0094 0.0094
Echinococcus granulosus G protein coupled receptor 139 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0302
Mycobacterium tuberculosis Conserved protein 0.007 0.0112 0.111
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0077 0.0127 0.0324
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0043 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0017 0.0119
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.005 0.076
Mycobacterium tuberculosis Putative ferredoxin reductase 0.044 0.0872 0.8958
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0112 0.111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0302
Schistosoma mansoni hypothetical protein 0.0033 0.0037 0.0037
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0327 0.0641 0.163
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0013 0.0255
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0013 0.0127
Schistosoma mansoni amine GPCR 0.0077 0.0127 0.0127
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.0042 0.0055 0.0139
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0052 0.0052
Schistosoma mansoni nuclear receptor 0.0019 0.0008 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0075 0.073
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0055 0.0139
Schistosoma mansoni jumonji domain containing protein 0.0118 0.0211 0.0211
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0013 0.0084
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Onchocerca volvulus 0.0327 0.0641 0.1621
Mycobacterium tuberculosis Conserved protein 0.007 0.0112 0.111
Entamoeba histolytica hypothetical protein 0.0107 0.0188 1
Onchocerca volvulus 0.0077 0.0127 0.0312
Brugia malayi hypothetical protein 0.0077 0.0127 0.0324
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0058 0.0531
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0327 0.0641 1
Schistosoma mansoni hypothetical protein 0.0166 0.031 0.031
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0082 0.1208
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0052 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Brugia malayi Dopamine receptor protein 2 0.0077 0.0127 0.0324
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.012 0.1943
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0071 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0027 0.0069
Onchocerca volvulus 0.0077 0.0127 0.0312
Brugia malayi conserved hypotetical protein 0.0019 0.0008 0.0019
Mycobacterium tuberculosis Probable dehydrogenase 0.044 0.0872 0.8958
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0172 0.0322 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0058 0.0147
Echinococcus granulosus serotonin receptor 0.0077 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.004 0.0348
Toxoplasma gondii ABC1 family protein 0.007 0.0112 0.1688
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0073 0.0073
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0013 0.0442
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0067 0.0105 0.1584
Echinococcus multilocularis glutamate synthase 0.0018 0.0005 0.0005
Brugia malayi G protein-coupled receptor F59B2.13 0.0077 0.0127 0.0324
Echinococcus multilocularis dro:myosuppressin receptor 0.0077 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0107 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0018 0.0005 0.0005
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0013 0.0255
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0327 0.0641 0.163
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Mycobacterium leprae conserved hypothetical protein 0.007 0.0112 0.111
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0077 0.0127 0.0127
Onchocerca volvulus 0.0077 0.0127 0.0312
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0077 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0041 0.0052 0.0052
Echinococcus multilocularis lysine specific demethylase 5A 0.0118 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0055 0.0082 0.0207
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0008 0.0008
Loa Loa (eye worm) beta-lactamase 0.007 0.0112 0.0285
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0052 0.0131
Brugia malayi nuclear receptor RXR 0.0019 0.0008 0.0019
Echinococcus granulosus 7TM GPCR rhodopsin 0.0077 0.0127 0.0127
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0112 0.1073
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0049 0.0069 0.0175
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0067 0.0105 0.8145
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0026 0.0364
Onchocerca volvulus 0.0041 0.0052 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0055 0.05
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0035 0.0302
Echinococcus multilocularis neuropeptide Y receptor 0.0077 0.0127 0.0127
Loa Loa (eye worm) inositol-1 0.0036 0.0043 0.0109
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.012 0.3629
Brugia malayi Probable ClpP-like protease 0.0078 0.0128 0.0327
Echinococcus multilocularis g protein coupled receptor 0.0077 0.0127 0.0127
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0077 0.0127 0.0127
Plasmodium vivax thioredoxin reductase, putative 0.0193 0.0364 0.5651
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Loa Loa (eye worm) hypothetical protein 0.007 0.0112 0.0285
Echinococcus granulosus thioredoxin glutathione reductase 0.0193 0.0364 0.0364
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0112 0.111
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0444 0.0881 0.224
Loa Loa (eye worm) norepinephrine transporter 0.1929 0.3934 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0096 0.2875
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0052 0.0131
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0131
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0057 0.0878
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0266 0.4409
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.004 0.0589
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0052 0.0131
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.005 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0193 0.0364 0.0364
Echinococcus granulosus orexin receptor type 2 0.0077 0.0127 0.0127
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.005 0.076
Loa Loa (eye worm) solute carrier family 6 member 4 0.1929 0.3934 1
Trypanosoma cruzi trypanothione reductase, putative 0.0067 0.0105 0.17
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0013 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0026 0.0217
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0013 0.0127
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0033 0.0479
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.012 0.1943
Plasmodium vivax hypothetical protein, conserved 0.0327 0.0641 1
Echinococcus granulosus expressed conserved protein 0.0092 0.0158 0.0158
Echinococcus multilocularis orexin receptor type 2 0.0077 0.0127 0.0127
Loa Loa (eye worm) TYRA-2 protein 0.0077 0.0127 0.0324
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0067 0.0105 0.1584
Schistosoma mansoni sodium-dependent amino acid transporter 0.0327 0.0641 0.0641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.004 0.0348
Onchocerca volvulus 0.0077 0.0127 0.0312
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0077 0.0127 0.0127
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0035 0.0313
Schistosoma mansoni neuropeptide receptor 0.0077 0.0127 0.0127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0105 0.17
Plasmodium vivax JmjC domain containing protein 0.0032 0.0033 0.0446
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0327 0.0641 0.0641
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0112 0.111
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.005 0.005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0112 0.0112
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.005 0.045
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0013 0.0136
Loa Loa (eye worm) hypothetical protein 0.0077 0.0127 0.0324
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.004 0.0348
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0013 0.0084
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0018 0.0005 0.0012
Onchocerca volvulus 0.0077 0.0127 0.0312
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.0128 0.1945
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0008 0.0019
Brugia malayi nuclear receptor NHR-88 0.0019 0.0008 0.0019
Onchocerca volvulus 0.0077 0.0127 0.0312
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0033 0.0084
Trichomonas vaginalis esterase, putative 0.007 0.0112 0.1073
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0074 0.012 0.3629
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0067 0.0105 0.17
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0112 0.3384
Schistosoma mansoni neuropeptide F-like receptor 0.0077 0.0127 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0102 0.0102
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0018 0.0005 0.0005
Echinococcus granulosus sex peptide receptor 0.0077 0.0127 0.0127
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0127 0.0127
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0008 0.0019
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0069 0.0175
Mycobacterium ulcerans hypothetical protein 0.0074 0.012 0.3629
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0077 0.0127 0.0324
Plasmodium falciparum transporter, putative 0.0327 0.0641 1
Echinococcus granulosus tm gpcr rhodopsin 0.0077 0.0127 0.0127
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0067 0.0105 0.17

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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