Detailed information for compound 816505

Basic information

Technical information
  • TDR Targets ID: 816505
  • Name: N-(2,4-dimethylphenyl)-4-methylquinolin-2-ami ne
  • MW: 262.349 | Formula: C18H18N2
  • H donors: 1 H acceptors: 1 LogP: 5.16 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C)Nc1cc(C)c2c(n1)cccc2
  • InChi: 1S/C18H18N2/c1-12-8-9-16(14(3)10-12)19-18-11-13(2)15-6-4-5-7-17(15)20-18/h4-11H,1-3H3,(H,19,20)
  • InChiKey: DTEOFKCSVNELKR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2,4-dimethylphenyl)-4-methyl-quinolin-2-amine
  • N-(2,4-dimethylphenyl)-4-methyl-2-quinolinamine
  • (2,4-dimethylphenyl)-(4-methyl-2-quinolyl)amine
  • CBMicro_008762
  • STOCK2S-22382
  • BIM-0008738.P001
  • Oprea1_346366
  • ZINC00199612

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0132 0.1639
Schistosoma mansoni nuclear hormone receptor 0.0074 0.0138 0.0584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Echinococcus multilocularis mitogen activated protein kinase 3 0.0101 0.0215 0.0913
Echinococcus granulosus Nuclear hormone receptor HR96 0.0035 0.0025 0.008
Loa Loa (eye worm) hypothetical protein 0.0214 0.0543 0.1262
Echinococcus granulosus 7TM GPCR rhodopsin 0.0143 0.0338 0.1155
Onchocerca volvulus 0.0035 0.0025 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0458 0.5761
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0074 0.0138 0.0285
Schistosoma mansoni neuropeptide F-like receptor 0.0143 0.0338 0.1567
Echinococcus multilocularis neuropeptides capa receptor 0.0143 0.0338 0.1441
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0026 0.0103
Schistosoma mansoni hypothetical protein 0.0143 0.0338 0.1567
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Onchocerca volvulus 0.0143 0.0338 0.0753
Schistosoma mansoni retinoic acid receptor RXR 0.0074 0.0138 0.0584
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0012 0.0125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0069 0.0229
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0248 0.5734
Echinococcus multilocularis neuropeptide s receptor 0.0143 0.0338 0.1441
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0032 0.0126
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0215 0.4974
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0066 0.0116 0.0269
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0143 0.0338 0.1567
Brugia malayi orphan nuclear receptor NR2E1 0.0035 0.0025 0.0059
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0047 0.011
Schistosoma mansoni aldehyde dehydrogenase 0.0136 0.0318 0.1467
Brugia malayi Hexokinase family protein 0.0051 0.0073 0.017
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0047 0.0139
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0074 0.0138 0.0582
Trypanosoma brucei hexokinase, putative 0.0082 0.0162 0.3719
Echinococcus granulosus thyroid hormone receptor alpha 0.0035 0.0025 0.008
Echinococcus granulosus orexin receptor type 2 0.0143 0.0338 0.1155
Mycobacterium leprae Conserved hypothetical protein 0.1172 0.3312 1
Echinococcus multilocularis mitogen activated protein kinase 0.0101 0.0215 0.0913
Loa Loa (eye worm) hypothetical protein 0.0175 0.0431 0.1001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0025 0.0099
Schistosoma mansoni inositol transporter 0.0042 0.0045 0.0129
Brugia malayi Nuclear hormone receptor-like 1 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0074
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0047 0.011
Trichomonas vaginalis chromobox protein, putative 0.0043 0.005 0.06
Loa Loa (eye worm) hypothetical protein 0.0513 0.1406 0.3269
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0086 0.0199
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0338 0.1155
Echinococcus granulosus single minded 2 0.0035 0.0026 0.0082
Brugia malayi beta-lactamase family protein 0.0037 0.0032 0.0074
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0074 0.0138 0.0467
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0011 0.0025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0143 0.0338 0.1155
Onchocerca volvulus 0.0143 0.0338 0.0753
Schistosoma mansoni hypothetical protein 0.0143 0.0338 0.1567
Echinococcus multilocularis FTZ F1 alpha 0.0074 0.0138 0.0582
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0047 0.0194
Schistosoma mansoni neuropeptide receptor 0.0143 0.0338 0.1567
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0012 0.0231
Onchocerca volvulus 0.0056 0.0086 0.0163
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi jmjC domain containing protein 0.0061 0.01 0.0231
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0047 0.0571
Loa Loa (eye worm) hypothetical protein 0.0145 0.0344 0.0801
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0032 0.0074
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0047 0.0139
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni organic anion transporter 0.0145 0.0344 0.1596
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0074 0.0138 0.0582
Echinococcus granulosus biogenic amine 5HT receptor 0.0143 0.0338 0.1155
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0105 0.0423
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0349 0.0811
Schistosoma mansoni follistatin 0.0066 0.0116 0.0474
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0047 0.0155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Brugia malayi hypothetical protein 0.0042 0.0047 0.011
Brugia malayi Phosphoglycerate kinase 0.0175 0.0431 0.1001
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0039 0.0037 0.0151
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.0431 0.5415
Brugia malayi Serotonin receptor 0.0143 0.0338 0.0787
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0035 0.0025 0.0099
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0143 0.0338 0.0787
Brugia malayi follicle stimulating hormone receptor 0.0597 0.165 0.3836
Echinococcus granulosus high affinity choline transporter 1 0.0379 0.1019 0.3494
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0175 0.0431 0.2236
Brugia malayi nuclear hormone receptor 0.0035 0.0025 0.0059
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0143 0.0338 0.1441
Entamoeba histolytica phosphoglycerate kinase, putative 0.0175 0.0431 0.5415
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0027 0.0317
Onchocerca volvulus 0.0143 0.0338 0.0753
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0143 0.0338 0.1567
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Onchocerca volvulus 0.0145 0.0344 0.0767
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.011
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.0431 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0301 0.0794 1
Brugia malayi PXA domain containing protein 0.0042 0.0047 0.011
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0101 0.0215 0.4974
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0143 0.0338 0.1567
Schistosoma mansoni neuropeptide F-like receptor 0.0143 0.0338 0.1567
Leishmania major phosphoglycerate kinase C, glycosomal 0.0175 0.0431 1
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0062 0.021
Echinococcus multilocularis neuropeptides capa receptor 0.0143 0.0338 0.1441
Loa Loa (eye worm) hypothetical protein 0.0039 0.0037 0.0087
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0143 0.0338 0.1155
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0145 0.0344 0.0801
Brugia malayi ThiF family protein 0.0033 0.0019 0.0044
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.012 0.0507
Echinococcus granulosus geminin 0.0368 0.0989 0.3392
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0012 0.0125
Echinococcus multilocularis somatostatin receptor 0.0143 0.0338 0.1441
Schistosoma mansoni amine GPCR 0.0143 0.0338 0.1567
Brugia malayi chromobox protein homolog 3 0.004 0.0041 0.0095
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0041 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0738 0.9293
Brugia malayi hypothetical protein 0.0042 0.0047 0.011
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0047 0.0194
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.01 0.0418
Brugia malayi MAP kinase sur-1 0.0101 0.0215 0.0501
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0132 0.1639
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0042 0.0045 0.0185
Onchocerca volvulus 0.0082 0.0162 0.034
Brugia malayi G protein-coupled receptor 0.0143 0.0338 0.0787
Schistosoma mansoni amine GPCR 0.0143 0.0338 0.1567
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0077 0.0146 0.3358
Brugia malayi beta-lactamase 0.0037 0.0032 0.0074
Loa Loa (eye worm) nuclear hormone receptor 0.0035 0.0025 0.0059
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0047 0.0155
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0066 0.0116 0.265
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus multilocularis neuropeptide Y receptor 0.0143 0.0338 0.1441
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.0431 0.202
Entamoeba histolytica hexokinase 1 0.0082 0.0162 0.2014
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0248 0.3105
Schistosoma mansoni hypothetical protein 0.0143 0.0338 0.1567
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0143 0.0338 0.1441
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Onchocerca volvulus 0.0051 0.0073 0.0134
Onchocerca volvulus 0.0037 0.0032 0.0037
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0047 0.0139
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0074 0.0138 0.0467
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0042 0.0046 0.0107
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0513 0.1406 0.3269
Echinococcus granulosus sodium:myo inositol cotransporter 0.0042 0.0045 0.0149
Brugia malayi GH02984p 0.0379 0.1019 0.2369
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0033 0.0019 0.0058
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0047 0.0155
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0175 0.0431 0.1216
Brugia malayi conserved hypotetical protein 0.0035 0.0025 0.0059
Echinococcus granulosus neuropeptide receptor A26 0.0143 0.0338 0.1155
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0338 0.1155
Brugia malayi jmjC domain containing protein 0.0062 0.0105 0.0245
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Loa Loa (eye worm) twinkle helicase 0.0114 0.0253 0.0588
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Leishmania major eukaryotic translation initiation factor-like 0.0035 0.0027 0.0586
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0074 0.0138 0.0321
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.011 0.2527
Schistosoma mansoni jumonji domain containing protein 0.0061 0.01 0.0395
Echinococcus multilocularis dro:myosuppressin receptor 0.0143 0.0338 0.1441
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0074 0.0138 0.0467
Onchocerca volvulus 0.0143 0.0338 0.0753
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0458 0.5761
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0143 0.0338 0.0787
Echinococcus multilocularis muscleblind protein 0.0154 0.0369 0.1571
Echinococcus multilocularis serotonin receptor 0.0143 0.0338 0.1441
Schistosoma mansoni organic anion transporter 0.0145 0.0344 0.1596
Echinococcus granulosus neuropeptide Y receptor 0.0143 0.0338 0.1155
Chlamydia trachomatis replicative DNA helicase 0.0398 0.1074 1
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0175 0.0431 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0101 0.0215 0.4974
Loa Loa (eye worm) hypothetical protein 0.0379 0.1019 0.2369
Schistosoma mansoni adenoreceptor 0.0143 0.0338 0.1567
Echinococcus granulosus GPCR family 2 0.0068 0.012 0.0406
Toxoplasma gondii hypothetical protein 0.005 0.0068 0.1538
Onchocerca volvulus Neuropeptide F receptor homolog 0.0143 0.0338 0.0753
Loa Loa (eye worm) hypothetical protein 0.0066 0.0116 0.0269
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0033 0.0019 0.0394
Brugia malayi Dopamine receptor protein 1 0.0143 0.0338 0.0787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0101 0.0215 0.4974
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0074 0.0138 0.0321
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0012 0.0125
Loa Loa (eye worm) hypothetical protein 0.0039 0.0037 0.0087
Schistosoma mansoni hypothetical protein 0.0068 0.012 0.0497
Onchocerca volvulus 0.0035 0.0026 0.0024
Entamoeba histolytica hypothetical protein 0.0042 0.0047 0.0571
Loa Loa (eye worm) hypothetical protein 0.0145 0.0344 0.0801
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0032 0.0101
Echinococcus granulosus Solute carrier family 22 5 0.1034 0.2912 1
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0132 0.0307
Echinococcus granulosus hexokinase 0.0082 0.0162 0.0548
Giardia lamblia Kinase, CMGC MAPK 0.0101 0.0215 0.2693
Brugia malayi prostaglandin transporter 0.1514 0.4301 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0035 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni RAR-like nuclear receptor 0.0074 0.0138 0.0584
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0042 0.0045 0.0185
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0101 0.0215 0.4974
Plasmodium vivax ubiquitin activating enzyme, putative 0.005 0.0068 0.1538
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0248 0.1123
Loa Loa (eye worm) hypothetical protein 0.005 0.0068 0.0158
Schistosoma mansoni zinc finger protein 0.0035 0.0025 0.0031
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0027 0.0586
Onchocerca volvulus 0.0143 0.0338 0.0753
Toxoplasma gondii transporter, major facilitator family protein 0.0145 0.0344 0.7985
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0487 0.6124
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.01 0.0418
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0047 0.0571
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0248 0.3105
Echinococcus multilocularis follistatin 0.0066 0.0116 0.0487
Schistosoma mansoni nuclear receptor nhr-48 0.0035 0.0025 0.0031
Onchocerca volvulus Putative organic anion transporter 0.0145 0.0344 0.0767
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.0431 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0145 0.0344 0.0801
Loa Loa (eye worm) hypothetical protein 0.0039 0.0037 0.0087
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.0431 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0025 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0738 0.9293
Loa Loa (eye worm) hypothetical protein 0.0073 0.0135 0.0314
Brugia malayi AKH receptor 0.0143 0.0338 0.0787
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0248 0.0576
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0074 0.0138 0.0321
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0074 0.0138 0.0584
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0105 0.0354
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0143 0.0338 0.0787
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0143 0.0338 0.1567
Schistosoma mansoni inositol transporter 0.0042 0.0045 0.0129
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0035 0.0025 0.0099
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0102 0.0344
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0136 0.0318 0.0287
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0458 0.5761
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0074 0.0138 0.0321
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0012 0.0231
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0033 0.0019 0.0394
Echinococcus multilocularis agrin 0.0066 0.0116 0.0487
Loa Loa (eye worm) hypothetical protein 0.0066 0.0116 0.0269
Brugia malayi beta-lactamase family protein 0.0037 0.0032 0.0074
Loa Loa (eye worm) DR-78 0.0035 0.0025 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0074 0.0138 0.0321
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0138 0.0467
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0069 0.0244
Loa Loa (eye worm) hypothetical protein 0.0031 0.0016 0.0037
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Brugia malayi steroid hormone receptor 0.0074 0.0138 0.0321
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0047 0.0194
Onchocerca volvulus Protein ultraspiracle homolog 0.0074 0.0138 0.0285
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0047 0.0194
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Echinococcus granulosus alpha 1A adrenergic receptor 0.0143 0.0338 0.1155
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0032 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni steroid hormone receptor ad4bp 0.0074 0.0138 0.0584
Echinococcus multilocularis GPCR, family 2 0.0068 0.012 0.0507
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0032 0.0374
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Schistosoma mansoni hypothetical protein 0.0068 0.012 0.0497
Schistosoma mansoni nuclear receptor 0.0035 0.0025 0.0031
Brugia malayi G-protein coupled receptor 0.0143 0.0338 0.0787
Schistosoma mansoni nuclear receptor 0.0035 0.0025 0.0031
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0047 0.0155
Onchocerca volvulus 0.0143 0.0338 0.0753
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus multilocularis serotonin receptor 0.0143 0.0338 0.1441
Echinococcus multilocularis g-protein coupled receptor 0.0143 0.0338 0.1441
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.005 0.0068 0.0282
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0047 0.011
Schistosoma mansoni alpha-1 adrenergic receptor 0.0143 0.0338 0.1567
Loa Loa (eye worm) hexokinase type II 0.0082 0.0162 0.0376
Echinococcus granulosus allatostatin A receptor 0.0143 0.0338 0.1155
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0398 0.1074 1
Onchocerca volvulus Putative organic anion transporter 0.0145 0.0344 0.0767
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0012 0.0125
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0032 0.0374
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0738 0.9293
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0143 0.0338 0.1441
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0047 0.0194
Brugia malayi PXA domain containing protein 0.0042 0.0047 0.011
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Brugia malayi hypothetical protein 0.0513 0.1406 0.3269
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0215 0.0963
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.0349 0.0318
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0074 0.0138 0.0467
Loa Loa (eye worm) hypothetical protein 0.0145 0.0344 0.0801
Echinococcus granulosus nuclear receptor nhr 48 0.0035 0.0025 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Brugia malayi sulfakinin receptor protein 0.0143 0.0338 0.0787
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0047 0.0194
Brugia malayi neuropeptide F receptor 0.0143 0.0338 0.0787
Brugia malayi SPARC precursor 0.0066 0.0116 0.0269
Onchocerca volvulus 0.0143 0.0338 0.0753
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0033 0.0019 0.0394
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus granulosus somatostatin receptor 0.0143 0.0338 0.1155
Loa Loa (eye worm) hypothetical protein 0.1514 0.4301 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0281 0.0738 0.1715
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0143 0.0338 0.1441
Brugia malayi intermediate filament protein 0.0056 0.0086 0.0199
Trypanosoma brucei hexokinase 0.0082 0.0162 0.3719
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0248 0.0844
Loa Loa (eye worm) runx1 0.0064 0.0111 0.0257
Echinococcus multilocularis phosphoglycerate kinase 1 0.0175 0.0431 0.1837
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.005 0.0068 0.1538
Schistosoma mansoni sumo-1-activating enzyme E1a 0.005 0.0068 0.024
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0248 0.0217
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0039 0.0037 0.0087
Loa Loa (eye worm) beta-lactamase 0.0037 0.0032 0.0074
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Onchocerca volvulus 0.0513 0.1406 0.3245
Brugia malayi GnHR receptor homolog 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus multilocularis G protein coupled receptor 139 0.0143 0.0338 0.1441
Schistosoma mansoni single-minded 0.0047 0.0062 0.021
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0074 0.0138 0.0584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0248 0.0576
Echinococcus granulosus Nuclear hormone receptor HR96 0.0035 0.0025 0.008
Loa Loa (eye worm) hexokinase 0.0082 0.0162 0.0376
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.0431 0.202
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0398 0.1074 1
Echinococcus granulosus expressed protein 0.0826 0.2313 0.7941
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0035 0.0025 0.0022
Brugia malayi hypothetical protein 0.0159 0.0384 0.0894
Onchocerca volvulus 0.0056 0.0086 0.0163
Brugia malayi ecdysone receptor 0.0035 0.0025 0.0059
Schistosoma mansoni hypothetical protein 0.0068 0.012 0.0497
Echinococcus granulosus phosphoglycerate kinase 1 0.0175 0.0431 0.1473
Schistosoma mansoni histamine h1 receptor 0.0143 0.0338 0.1567
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.005 0.0079
Echinococcus multilocularis chromobox protein 1 0.0072 0.0132 0.0556
Trypanosoma cruzi MFS transporter, putative 0.0145 0.0344 0.7985
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0037 0.0087
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0143 0.0338 0.1567
Echinococcus multilocularis allatostatin A receptor 0.0143 0.0338 0.1441
Brugia malayi photoreceptor-specific nuclear receptor 0.0074 0.0138 0.0321
Schistosoma mansoni amine GPCR 0.0143 0.0338 0.1567
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0143 0.0338 0.1567
Echinococcus granulosus Solute carrier organic anion transporter family 0.0145 0.0344 0.1176
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Schistosoma mansoni hypothetical protein 0.0146 0.0347 0.1611
Brugia malayi Tachykinin-like peptides receptor 99D 0.0143 0.0338 0.0787
Brugia malayi translation initiation factor 4E 0.0035 0.0027 0.0063
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0143 0.0338 0.1567
Plasmodium vivax hexokinase, putative 0.0082 0.0162 0.3719
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Brugia malayi nuclear hormone receptor family member nhr-6 0.0035 0.0025 0.0059
Toxoplasma gondii ThiF family protein 0.0033 0.0019 0.0394
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0145 0.0344 0.0801
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.0794 1
Giardia lamblia Phosphoglycerate kinase 0.0175 0.0431 0.5415
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0032 0.0691
Schistosoma mansoni biogenic amine (5HT) receptor 0.0143 0.0338 0.1567
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.005 0.0152
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0039 0.0037 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0143 0.0338 0.1441
Brugia malayi hypothetical protein 0.0039 0.0037 0.0087
Onchocerca volvulus Glucosylceramidase homolog 0.0185 0.0458 0.1032
Loa Loa (eye worm) hypothetical protein 0.0044 0.0052 0.012
Onchocerca volvulus 0.0145 0.0344 0.0767
Toxoplasma gondii hexokinase 0.0082 0.0162 0.3719
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0027 0.0586
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0032 0.0054
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni chromobox protein 0.0072 0.0132 0.0554
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0028 0.0006 0.0087
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni sodium/solute symporter 0.0042 0.0045 0.0129
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0143 0.0338 0.0787
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0074 0.0138 0.0321
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0012 0.0125
Loa Loa (eye worm) hypothetical protein 0.0039 0.0039 0.009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus multilocularis expressed protein 0.0826 0.2313 0.9904
Echinococcus granulosus sodium:glucose cotransporter 2 0.0042 0.0045 0.0149
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0074 0.0138 0.0582
Echinococcus granulosus g protein coupled receptor 0.0143 0.0338 0.1155
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0032 0.0691
Schistosoma mansoni growth hormone secretagogue receptor 0.0143 0.0338 0.1567
Schistosoma mansoni intermediate filament proteins 0.0056 0.0086 0.0326
Echinococcus multilocularis geminin 0.0368 0.0989 0.423
Loa Loa (eye worm) hypothetical protein 0.0056 0.0086 0.02
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0138 0.0582
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.32 0.9172 0.9169
Echinococcus multilocularis chromobox protein 1 0.0072 0.0132 0.0556
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0318 0.2787
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0047 0.011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0069 0.0229
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0248 0.0576
Schistosoma mansoni neuropeptide receptor 0.0143 0.0338 0.1567
Plasmodium vivax phosphoglycerate kinase, putative 0.0175 0.0431 1
Trypanosoma brucei hexokinase 0.0082 0.0162 0.3719
Brugia malayi Bromodomain containing protein 0.0039 0.0039 0.009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Leishmania major ubiquitin-activating enzyme-like protein 0.0033 0.0019 0.0394
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0738 0.9293
Onchocerca volvulus 0.0143 0.0338 0.0753
Brugia malayi Phosphoglycerate kinase 0.0064 0.011 0.0257
Echinococcus granulosus ecdysone induced protein 78C 0.0074 0.0138 0.0467
Echinococcus granulosus tm gpcr rhodopsin 0.0143 0.0338 0.1155
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0338 0.1155
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0032 0.0691
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0145 0.0344 0.1467
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0027 0.0317
Schistosoma mansoni high-affinity choline transporter 0.0379 0.1019 0.4905
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0077 0.0146 0.3358
Echinococcus granulosus agrin 0.0066 0.0116 0.039
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0047 0.0155
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0143 0.0338 0.1567
Echinococcus granulosus fmrfamide receptor 0.0143 0.0338 0.1155
Echinococcus multilocularis g protein coupled receptor 0.0143 0.0338 0.1441
Onchocerca volvulus 0.0143 0.0338 0.0753
Leishmania major hypothetical protein, conserved 0.0037 0.0032 0.0691
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0012 0.0125
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.01 0.0335
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0032 0.0374
Schistosoma mansoni aldehyde dehydrogenase 0.0136 0.0318 0.1467
Brugia malayi nuclear receptor RXR 0.0039 0.0037 0.0087
Schistosoma mansoni biogenic amine receptor 0.0143 0.0338 0.1567
Echinococcus granulosus SUMO activating enzyme subunit 1 0.005 0.0068 0.0226
Loa Loa (eye worm) hypothetical protein 0.0056 0.0086 0.0199
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0143 0.0338 0.0787
Schistosoma mansoni neuropeptide receptor 0.0143 0.0338 0.1567
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0143 0.0338 0.0787
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0042 0.0045 0.0185
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0102 0.0429
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0035 0.0027 0.0586
Brugia malayi 6-phosphofructokinase 0.0112 0.0248 0.0576
Echinococcus multilocularis nuclear receptor nhr 48 0.0035 0.0025 0.0099
Echinococcus multilocularis solute carrier family 5 0.0042 0.0045 0.0185
Echinococcus granulosus muscleblind protein 0.0154 0.0369 0.126
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0143 0.0338 0.1441
Loa Loa (eye worm) hypothetical protein 0.0154 0.0369 0.0858
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0035 0.0027 0.0086
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0248 0.3105
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0143 0.0338 0.1441
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.011
Brugia malayi 6-phosphofructokinase 0.0112 0.0248 0.0576
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0069 0.016
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0043 0.005 0.0116
Mycobacterium ulcerans beta-lactamase 0.0037 0.0032 0.0054
Onchocerca volvulus 0.0145 0.0344 0.0767
Loa Loa (eye worm) hypothetical protein 0.0066 0.0116 0.0269
Schistosoma mansoni amine GPCR 0.0143 0.0338 0.1567
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0101 0.0215 0.4974
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0074 0.0138 0.0321
Loa Loa (eye worm) G-protein coupled receptor 0.0143 0.0338 0.0787
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0338 0.1155
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.011 0.2527
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0011 0.0025
Entamoeba histolytica hypothetical protein 0.0042 0.0047 0.0571
Schistosoma mansoni hypothetical protein 0.0368 0.0989 0.4759
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0074
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0032 0.0691
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0248 0.5734
Schistosoma mansoni hypothetical protein 0.0368 0.0989 0.4759
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0023 0.0498
Schistosoma mansoni opsin-like receptor 0.0143 0.0338 0.1567
Echinococcus granulosus solute carrier family 5 0.0042 0.0045 0.0149
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0047 0.0155
Schistosoma mansoni opsin-like receptor 0.0143 0.0338 0.1567
Echinococcus multilocularis hexokinase type 2 0.0082 0.0162 0.0683
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0042 0.0045 0.1009
Schistosoma mansoni amine GPCR 0.0143 0.0338 0.1567
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0143 0.0338 0.1567
Brugia malayi Heterochromatin protein 1 0.0072 0.0132 0.0307
Echinococcus multilocularis neuropeptide FF receptor 2 0.0143 0.0338 0.1441
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0338 0.1155
Onchocerca volvulus 0.0145 0.0344 0.0767
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0248 0.1053
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.012 0.0507
Schistosoma mansoni hypothetical protein 0.0068 0.012 0.0497
Brugia malayi Dopamine receptor 0.0143 0.0338 0.0787
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0007 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0248 0.3105
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0012 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.012 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0007 0.006
Echinococcus granulosus lamin 0.0056 0.0086 0.0287
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0026 0.0061
Onchocerca volvulus 0.0035 0.0025 0.0022
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0074 0.0138 0.0584
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0035 0.0025 0.0059
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0043 0.005 0.0116
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.012 0.0406
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0012 0.0125
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0012 0.0125
Schistosoma mansoni neuropeptide f receptor 76f 0.0143 0.0338 0.1567
Brugia malayi RE15519p 0.0143 0.0338 0.0787
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0248 0.3105
Echinococcus granulosus dro:myosuppressin receptor 0.0143 0.0338 0.1155
Loa Loa (eye worm) hexokinase 0.0082 0.0162 0.0376
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0012 0.0231
Echinococcus granulosus neuropeptides capa receptor 0.0143 0.0338 0.1155
Chlamydia trachomatis recombinase RecA 0.0111 0.0246 0.22
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0047 0.0571
Schistosoma mansoni neuropeptide receptor 0.0143 0.0338 0.1567
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Echinococcus multilocularis hexokinase 0.0082 0.0162 0.0683
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0136 0.0318 0.1086
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0066 0.0116 0.0269
Treponema pallidum recombinase A 0.0111 0.0246 0.22
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0143 0.0338 0.1441
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0215 0.2693
Echinococcus multilocularis neuropeptide receptor A26 0.0143 0.0338 0.1441
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.005 0.0152
Treponema pallidum phosphoglycerate kinase 0.0175 0.0431 0.3944
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0069 0.016
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0145 0.0344 0.1467
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0318 0.2787
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.0543 0.1262
Leishmania major hexokinase, putative 0.0082 0.0162 0.3719
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0047 0.011
Schistosoma mansoni lamin 0.0056 0.0086 0.0326
Brugia malayi sodium-independent organic anion transporter family protein 0.0145 0.0344 0.0801
Onchocerca volvulus 0.0037 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi hypothetical protein 0.0145 0.0344 0.0801
Brugia malayi hypoxia-induced factor 1 0.0147 0.0349 0.0811
Brugia malayi Latrophilin receptor protein 2 0.0068 0.012 0.028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0136 0.0318 0.1354
Brugia malayi G-protein coupled receptor 0.0143 0.0338 0.0787
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0047 0.0194
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0143 0.0338 0.1441
Brugia malayi putative neuropeptide receptor 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Onchocerca volvulus 0.0143 0.0338 0.0753
Schistosoma mansoni hexokinase 0.0082 0.0162 0.0699
Plasmodium falciparum phosphoglycerate kinase 0.0175 0.0431 1
Echinococcus granulosus chromobox protein 1 0.0072 0.0132 0.0446
Brugia malayi nuclear receptor NHR-88 0.0035 0.0025 0.0059
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0143 0.0338 0.1441
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.0609 0.0579
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0143 0.0338 0.0787
Echinococcus multilocularis hexokinase 0.0082 0.0162 0.0683
Echinococcus granulosus tm gpcr rhodopsin 0.0143 0.0338 0.1155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0074 0.0138 0.0321
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0012 0.0231
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0281 0.0738 0.1715
Entamoeba histolytica hexokinase 2 0.0082 0.0162 0.2014
Onchocerca volvulus 0.0143 0.0338 0.0753
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.0543 0.1262
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0143 0.0338 0.1155
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0338 0.1155
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0037 0.009
Toxoplasma gondii aldehyde dehydrogenase 0.0136 0.0318 0.7372
Loa Loa (eye worm) nuclear receptor NHR-67 0.0035 0.0025 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0069 0.0285
Treponema pallidum hexokinase (hxk) 0.0082 0.0162 0.1408
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0034 0.0023 0.0498
Loa Loa (eye worm) ThiF family protein 0.0033 0.0019 0.0044
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0086 0.0199
Onchocerca volvulus Hexokinase homolog 0.0051 0.0073 0.0134
Chlamydia trachomatis phosphoglycerate kinase 0.0175 0.0431 0.3944
Schistosoma mansoni myosin xvIII 0.0143 0.0338 0.1567
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0047 0.0139
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0002 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0143 0.0338 0.1155
Mycobacterium ulcerans lipase LipD 0.0037 0.0032 0.0054
Echinococcus granulosus g protein coupled receptor 0.0143 0.0338 0.1155
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0066 0.0116 0.0269
Trypanosoma brucei protein kinase, putative 0.0101 0.0215 0.4974
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0074
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0042 0.0045 0.0106
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0086 0.0199
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0175 0.0431 1
Echinococcus granulosus neuropeptides capa receptor 0.0143 0.0338 0.1155
Echinococcus multilocularis neuropeptide receptor 0.0143 0.0338 0.1441
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0041 0.0489
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0074 0.0138 0.0584
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0035 0.0025 0.0031
Loa Loa (eye worm) neuropeptide F receptor 0.0143 0.0338 0.0787
Echinococcus granulosus peptide allatostatin:somatostatin 0.0143 0.0338 0.1155
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0047 0.0194
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0047 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0047 0.0571
Echinococcus multilocularis high affinity choline transporter 1 0.0379 0.1019 0.4357
Brugia malayi hypothetical protein 0.0035 0.0025 0.0059
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0025 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0458 0.5761
Echinococcus granulosus mitogen activated protein kinase 0.0101 0.0215 0.0732
Echinococcus granulosus chromobox protein 1 0.0072 0.0132 0.0446
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0101 0.0215 0.0501
Echinococcus granulosus serotonin receptor 0.0143 0.0338 0.1155
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0069 0.0244
Echinococcus granulosus neuropeptide receptor 0.0143 0.0338 0.1155
Brugia malayi tailless protein 0.0035 0.0025 0.0059
Onchocerca volvulus 0.0066 0.0116 0.0233
Treponema pallidum replicative DNA helicase (dnaB) 0.0398 0.1074 1
Schistosoma mansoni bromodomain containing protein 0.0065 0.0113 0.046
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.0347 0.0808
Loa Loa (eye worm) hypothetical protein 0.0068 0.012 0.028
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0035 0.0027 0.0586
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Brugia malayi Nuclear hormone receptor E75 0.0035 0.0025 0.0059
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0066 0.0116 0.265
Brugia malayi hypothetical protein 0.0035 0.0025 0.0059
Schistosoma mansoni biogenic amine receptor 0.0143 0.0338 0.1567
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus granulosus hexokinase 0.0082 0.0162 0.0548
Echinococcus multilocularis neuropeptide receptor 0.0143 0.0338 0.1441
Echinococcus granulosus tm gpcr rhodopsin 0.0143 0.0338 0.1155
Echinococcus granulosus sex peptide receptor 0.0143 0.0338 0.1155
Onchocerca volvulus 0.0042 0.0045 0.0069
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0143 0.0338 0.1155
Echinococcus multilocularis G-protein coupled receptor, putative 0.0143 0.0338 0.1441
Onchocerca volvulus 0.0143 0.0338 0.0753
Echinococcus granulosus intermediate filament protein 0.0056 0.0086 0.0287
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0074
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0301 0.0794 1
Toxoplasma gondii ABC1 family protein 0.0037 0.0032 0.0691
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0138 0.0467
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0047 0.0139
Toxoplasma gondii protease inhibitor PI2 0.0066 0.0116 0.265
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0074 0.0138 0.0467
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0248 0.0659
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0035 0.0025 0.0022
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0145 0.0344 0.1176
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi Serotonin receptor 0.0143 0.0338 0.0787
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0066 0.0116 0.265
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0042 0.0045 0.0149
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0738 0.2057 1
Trichomonas vaginalis esterase, putative 0.0037 0.0032 0.0374
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0215 0.2693
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0002 0.0005
Brugia malayi G protein-coupled receptor F59B2.13 0.0143 0.0338 0.0787
Brugia malayi larval opioid receptor 0.0143 0.0338 0.0787
Echinococcus multilocularis neuropeptide Y receptor 0.0143 0.0338 0.1441
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0047 0.0139
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0143 0.0338 0.0787
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.012 0.028
Brugia malayi hypothetical protein 0.0039 0.0037 0.0087
Onchocerca volvulus Bile acid receptor homolog 0.0074 0.0138 0.0285
Mycobacterium ulcerans recombinase A 0.0111 0.0246 0.2095
Schistosoma mansoni chromobox protein 0.0072 0.0132 0.0554
Brugia malayi Flap endonuclease-1 0.0027 0.0002 0.0005
Echinococcus granulosus mitogen activated protein kinase 3 0.0101 0.0215 0.0732
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0027 0.0317
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0047 0.0139
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0012 0.0231
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0143 0.0338 0.1441
Echinococcus granulosus tachykinin peptides receptor 99D 0.0143 0.0338 0.1155
Schistosoma mansoni lamin 0.0056 0.0086 0.0326
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0032 0.0102
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.011
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0074 0.0138 0.0584
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0066 0.0116 0.0269
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0047 0.011
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0143 0.0338 0.1567
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0074 0.0138 0.0321
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0248 0.2117
Echinococcus multilocularis sex peptide receptor 0.0143 0.0338 0.1441
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0597 0.165 0.3836
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0032 0.0127
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0458 0.5761
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0047 0.0139
Echinococcus multilocularis muscleblind protein 1 0.0154 0.0369 0.1571
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi ORL1-like opioid receptor 0.0143 0.0338 0.0787
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0027 0.0317
Echinococcus granulosus hexokinase 0.0082 0.0162 0.0548
Trypanosoma cruzi hexokinase, putative 0.0082 0.0162 0.3719
Brugia malayi Hexokinase family protein 0.0082 0.0162 0.0376
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0248 0.3105
Echinococcus multilocularis orexin receptor type 2 0.0143 0.0338 0.1441
Echinococcus granulosus hexokinase type 2 0.0082 0.0162 0.0548
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0039 0.0037 0.009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0074 0.0138 0.0321
Leishmania major hexokinase, putative 0.0082 0.0162 0.3719
Brugia malayi Steroid receptor seven-up type 2 0.0074 0.0138 0.0321
Brugia malayi nuclear receptor NHR-88 0.0074 0.0138 0.0321
Mycobacterium ulcerans hypothetical protein 0.0037 0.0032 0.0054
Brugia malayi hexokinase 0.0082 0.0162 0.0376
Loa Loa (eye worm) steroid hormone receptor 0.0074 0.0138 0.0321
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0111 0.0246 0.0652
Loa Loa (eye worm) hypothetical protein 0.0154 0.0369 0.0858
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.0431 1
Leishmania major eukaryotic translation initiation factor-like protein 0.0035 0.0027 0.0586
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0066 0.0116 0.0269
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0248 0.1123
Loa Loa (eye worm) hypothetical protein 0.0039 0.0037 0.0087
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi putative neuropeptide receptor NPR1 0.0143 0.0338 0.0787
Onchocerca volvulus 0.0143 0.0338 0.0753
Loa Loa (eye worm) neuropeptide F receptor 0.0143 0.0338 0.0787
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0143 0.0338 0.1155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0738 0.9293
Echinococcus multilocularis fmrfamide receptor 0.0143 0.0338 0.1441
Brugia malayi nuclear receptor RXR 0.0035 0.0025 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0458 0.5761
Onchocerca volvulus Putative organic anion transporter 0.1514 0.4301 1
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0301 0.0794 1
Schistosoma mansoni lozenge 0.0064 0.0111 0.0449
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0047 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0487 0.6124
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.005 0.0152
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.0543 0.1262
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0143 0.0338 0.1567
Onchocerca volvulus 0.0143 0.0338 0.0753
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0041 0.0489
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0047 0.0139
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0064 0.011 0.2527
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0033 0.0019 0.0072
Brugia malayi sodium-independent organic anion transporter family protein 0.0145 0.0344 0.0801
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0047 0.0155
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.0349 0.0968
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0338 0.1155
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0105 0.0423
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0032 0.0062
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0143 0.0338 0.0753
Schistosoma mansoni coup transcription factor 0.0074 0.0138 0.0584
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0035 0.0027 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0074 0.0138 0.0321
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0215 0.2693
Entamoeba histolytica hypothetical protein 0.0042 0.0047 0.0571
Brugia malayi hypothetical protein 0.0145 0.0344 0.0801
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.012 0.028
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0043 0.005 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0074 0.0138 0.0584
Echinococcus multilocularis beta adrenergic receptor kinase 0.0043 0.005 0.0205
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0458 0.5761
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0047 0.0571
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0143 0.0338 0.1441
Mycobacterium ulcerans phosphoglycerate kinase 0.0175 0.0431 0.3862
Onchocerca volvulus 0.0143 0.0338 0.0753
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0074 0.0138 0.0321
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0032 0.0374
Brugia malayi PAS domain containing protein 0.0047 0.0062 0.0144
Trichomonas vaginalis chromobox protein, putative 0.0043 0.005 0.06
Brugia malayi nuclear receptor NHR-67 0.0035 0.0025 0.0059
Echinococcus multilocularis Protein lozenge 0.0064 0.0111 0.0465
Schistosoma mansoni biogenic amine (5HT) receptor 0.0143 0.0338 0.1567
Loa Loa (eye worm) melatonin receptor type 1A 0.0143 0.0338 0.0787
Brugia malayi phosphofructokinase 0.0112 0.0248 0.0576
Loa Loa (eye worm) hypothetical protein 0.004 0.0041 0.0095
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0175 0.0431 0.04
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0074 0.0138 0.0321
Loa Loa (eye worm) G-protein coupled receptor 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Echinococcus granulosus FTZ F1 alpha 0.0074 0.0138 0.0467
Brugia malayi Dopamine receptor protein 2 0.0143 0.0338 0.0787
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0834 0.2335 1
Brugia malayi ThiF family protein 0.005 0.0068 0.0158
Trypanosoma brucei phosphoglycerate kinase 0.0064 0.011 0.2527
Trypanosoma brucei phosphoglycerate kinase, putative 0.0064 0.011 0.2527
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0047 0.0571
Echinococcus granulosus G protein coupled receptor 139 0.0143 0.0338 0.1155
Echinococcus multilocularis g protein coupled receptor 0.0143 0.0338 0.1441
Brugia malayi ecdysteroid receptor 0.0074 0.0138 0.0321
Onchocerca volvulus 0.0074 0.0138 0.0285
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi Muscleblind-like protein 0.0154 0.0369 0.0858
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0215 0.4974
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0074 0.0138 0.0321
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0037 0.0087
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0039 0.0037 0.0121
Loa Loa (eye worm) hexokinase 0.0051 0.0073 0.017
Echinococcus granulosus beta-adrenergic receptor kinase 0.0043 0.005 0.0164
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0143 0.0338 0.1155
Loa Loa (eye worm) hypothetical protein 0.0055 0.0083 0.0192
Mycobacterium ulcerans aldehyde dehydrogenase 0.0136 0.0318 0.2787
Echinococcus granulosus g-protein coupled receptor 0.0143 0.0338 0.1155
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0143 0.0338 0.1567
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0069 0.0244
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Brugia malayi Melatonin receptor type 1A 0.0143 0.0338 0.0787
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0066 0.0116 0.265
Schistosoma mansoni hypothetical protein 0.0143 0.0338 0.1567
Onchocerca volvulus 0.0143 0.0338 0.0753
Onchocerca volvulus 0.0082 0.0162 0.034
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0035 0.0027 0.0586
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0398 0.1074 0.3176
Brugia malayi nuclear hormone receptor 0.0074 0.0138 0.0321
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0248 0.5734
Echinococcus multilocularis ecdysone induced protein 78C 0.0074 0.0138 0.0582
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0027 0.0317
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0032 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0074 0.0138 0.0321
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0047 0.0139
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0012 0.0231
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0027 0.0317
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0023 0.0498
Onchocerca volvulus 0.0082 0.0162 0.034
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0035 0.0025 0.0099
Brugia malayi Bromodomain containing protein 0.0077 0.0148 0.0343
Plasmodium falciparum hexokinase 0.0082 0.0162 0.3719
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus granulosus follistatin 0.0066 0.0116 0.039
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0248 0.3105
Echinococcus granulosus sodium:glucose cotransporter 0.0042 0.0045 0.0149
Brugia malayi Sodium:solute symporter family protein 0.0042 0.0045 0.0106
Echinococcus granulosus g protein coupled receptor 0.0143 0.0338 0.1155
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.0431 0.5415
Echinococcus multilocularis hexokinase 0.0082 0.0162 0.0683
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0042 0.0047 0.011
Loa Loa (eye worm) hypothetical protein 0.0159 0.0384 0.0894
Echinococcus granulosus neuropeptide FF receptor 2 0.0143 0.0338 0.1155
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0143 0.0338 0.1441
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0045 0.0055 0.0176
Echinococcus multilocularis expressed protein 0.0066 0.0116 0.0487
Schistosoma mansoni biogenic amine receptor 0.0143 0.0338 0.1567
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0215 0.2693
Trypanosoma cruzi hexokinase, putative 0.0082 0.0162 0.3719
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0143 0.0338 0.1567
Loa Loa (eye worm) hypothetical protein 0.0037 0.0032 0.0074
Onchocerca volvulus 0.0143 0.0338 0.0753
Schistosoma mansoni Replicative DNA helicase 0.0398 0.1074 0.5174
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0138 0.0582
Schistosoma mansoni agrin 0.0066 0.0116 0.0474
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0338 0.1441
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0077 0.0146 0.3358
Schistosoma mansoni opsin-like receptor 0.0143 0.0338 0.1567
Echinococcus multilocularis lamin dm0 0.0056 0.0086 0.0358
Echinococcus multilocularis g protein coupled receptor 0.0143 0.0338 0.1441
Echinococcus multilocularis lamin 0.0056 0.0086 0.0358
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0035 0.0025 0.0059
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0143 0.0338 0.1441
Loa Loa (eye worm) hypothetical protein 0.0146 0.0347 0.0808
Loa Loa (eye worm) translation initiation factor 4E 0.0035 0.0027 0.0063
Onchocerca volvulus 0.0037 0.0032 0.0037
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0074 0.0138 0.0582
Leishmania major phosphoglycerate kinase B, cytosolic 0.0175 0.0431 1
Echinococcus multilocularis musashi 0.0056 0.0086 0.0358
Brugia malayi neuropeptide F receptor 0.0143 0.0338 0.0787
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0047 0.0139
Treponema pallidum fructose-bisphosphate aldolase 0.0301 0.0794 0.7363
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0032 0.0074
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0035 0.0025 0.0099
Echinococcus granulosus hypothetical protein 0.0143 0.0338 0.1155
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0069 0.0285
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0101 0.0215 0.4974
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0035 0.0025 0.0059
Echinococcus granulosus neuropeptide s receptor 0.0143 0.0338 0.1155
Brugia malayi hypothetical protein 0.0143 0.0338 0.0787
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0074 0.0138 0.0321
Loa Loa (eye worm) hypothetical protein 0.0066 0.0116 0.0269
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Echinococcus granulosus 7tm_1 domain containing protein 0.0143 0.0338 0.1155
Trichomonas vaginalis glucosylceramidase, putative 0.0281 0.0738 0.9293
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0033 0.0019 0.0394
Loa Loa (eye worm) hypothetical protein 0.0145 0.0344 0.0801
Echinococcus multilocularis thyroid hormone receptor alpha 0.0074 0.0138 0.0582
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0136 0.0318 0.7372
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0338 0.1567
Onchocerca volvulus 0.0145 0.0344 0.0767
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0035 0.0025 0.008
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0012 0.0231
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0035 0.0027 0.004
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0248 0.2222
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0105 0.0245
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0047 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0074 0.0138 0.0321
Loa Loa (eye worm) agrin synaptic family protein 0.0066 0.0116 0.0269
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0143 0.0338 0.0787
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0047 0.0571
Echinococcus granulosus biogenic amine 5HT receptor 0.0143 0.0338 0.1155
Loa Loa (eye worm) hypothetical protein 0.0145 0.0344 0.0801
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0074 0.0138 0.0584
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.0349 0.3084
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0143 0.0338 0.1441
Echinococcus granulosus neuropeptide receptor 0.0143 0.0338 0.1155
Echinococcus granulosus lamin dm0 0.0056 0.0086 0.0287
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0047 0.0194
Schistosoma mansoni thyroid hormone receptor 0.0074 0.0138 0.0584
Loa Loa (eye worm) hypothetical protein 0.0143 0.0338 0.0787
Loa Loa (eye worm) TYRA-2 protein 0.0143 0.0338 0.0787
Brugia malayi secreted modular calcium-binding protein 1 0.0066 0.0116 0.0269

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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