Detailed information for compound 826719

Basic information

Technical information
  • TDR Targets ID: 826719
  • Name: 2-(2-chlorophenyl)-1-propylbenzimidazole
  • MW: 270.757 | Formula: C16H15ClN2
  • H donors: 0 H acceptors: 1 LogP: 4.56 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCn1c(nc2c1cccc2)c1ccccc1Cl
  • InChi: 1S/C16H15ClN2/c1-2-11-19-15-10-6-5-9-14(15)18-16(19)12-7-3-4-8-13(12)17/h3-10H,2,11H2,1H3
  • InChiKey: BOHZCUKKUIMHBR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-chlorophenyl)-1-propyl-benzimidazole
  • ChemDiv3_015827
  • ST5108453
  • ZINC04748984

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0028 0.0012 0.0003
Loa Loa (eye worm) cytochrome P450 family protein 0.034 0.0665 0.2118
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0274 0.0527 0.0744
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0045 0.0121
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0033 0.0037
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0045 0.0131
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0191 0.0614
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.008 0.0234
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0055 0.0155
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.0211 0.3655
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0212 0.0397 0.5755
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0078 0.0117 0.5724
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0078 0.0117 1
Loa Loa (eye worm) glutamate receptor 0.0027 0.0011 0.0012
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1411 0.2911 0.9337
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0095 0.0285
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0212 0.0397 0.5755
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0045 0.0049 0.006
Leishmania major cytochrome p450-like protein 0.034 0.0665 0.2108
Onchocerca volvulus 0.0043 0.0045 0.0114
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0018 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0212 0.0397 0.7288
Echinococcus multilocularis tumor protein p63 0.0353 0.0693 0.0981
Brugia malayi Receptor family ligand binding region containing protein 0.0027 0.0011 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0019 0.0017
Mycobacterium leprae Conserved hypothetical protein 0.0212 0.0397 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0033 0.0072
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0032 0.0021 0.002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0045 0.0049 0.0042
Echinococcus multilocularis roundabout 2 0.0045 0.0049 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0012 0.0017
Echinococcus multilocularis nmda type glutamate receptor 0.0237 0.0451 0.0635
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0095 0.0273
Echinococcus multilocularis chromobox protein 1 0.0073 0.0106 0.0142
Loa Loa (eye worm) glutamate receptor 1 0.0161 0.029 0.091
Leishmania major cytochrome p450-like protein 0.0212 0.0397 0.1244
Loa Loa (eye worm) TK protein kinase 0.0039 0.0035 0.009
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0188 0.0347 0.0487
Plasmodium falciparum glutathione reductase 0.0049 0.0055 0.04
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0027 0.0011 0.0012
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0212 0.0397 0.5755
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0033 0.0089
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.005 0.014
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.0211 0.3655
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.005 0.014
Echinococcus multilocularis roundabout 2 0.0254 0.0485 0.0684
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0018 0.0005
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0078 0.0117 0.5724
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0191 0.0593
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.008 0.0234
Loa Loa (eye worm) glutathione reductase 0.0049 0.0055 0.0155
Onchocerca volvulus 0.0033 0.0023 0.0041
Echinococcus granulosus metabotropic glutamate receptor 5 0.0027 0.0011 0.0006
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.336 0.6993 1
Mycobacterium ulcerans beta-lactamase 0.0043 0.0045 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0027 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0012 0.0019
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0111 0.0185 0.3149
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0509 0.1685
Echinococcus multilocularis peroxidasin 0.0045 0.0049 0.006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0045 0.0128
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.005 0.014
Brugia malayi intermediate filament protein 0.0028 0.0012 0.0015
Schistosoma mansoni protein kinase 0.0032 0.0021 0.0014
Loa Loa (eye worm) hypothetical protein 0.0208 0.039 0.1232
Trypanosoma cruzi cytochrome P450, putative 0.034 0.0665 0.2108
Schistosoma mansoni lamin 0.0028 0.0012 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0191 0.062
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0032 0.0068
Giardia lamblia Aurora kinase 0.0483 0.0965 0.319
Schistosoma mansoni nephrin 0.0228 0.0432 0.0425
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0055 0.04
Schistosoma mansoni intermediate filament proteins 0.0028 0.0012 0.0005
Echinococcus multilocularis twitchin 0.0033 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.001 0.0012
Leishmania major hypothetical protein, conserved 0.0043 0.0045 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0018 0.0038
Plasmodium vivax glutathione reductase, putative 0.0049 0.0055 0.04
Mycobacterium leprae Probable lipase LipE 0.0043 0.0045 0.0537
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0338 0.1111
Echinococcus granulosus microtubule associated protein 2 0.0708 0.1438 0.2048
Schistosoma mansoni lamin 0.0028 0.0012 0.0005
Brugia malayi beta-lactamase family protein 0.0043 0.0045 0.0121
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0121
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0191 0.0185
Echinococcus granulosus roundabout 2 0.0254 0.0485 0.0684
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.004 0.0033
Loa Loa (eye worm) AUR protein kinase 0.0483 0.0965 0.3081
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0079 0.0118 0.0159
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0079 0.0118 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0027 0.0067
Schistosoma mansoni glutamate receptor kainate 0.0161 0.029 0.0283
Schistosoma mansoni protein kinase 0.0046 0.005 0.0044
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0191 0.0606
Plasmodium falciparum serine/threonine protein kinase, putative 0.0483 0.0965 1
Echinococcus multilocularis Immunoglobulin 0.0208 0.039 0.0548
Echinococcus multilocularis glutamate receptor 2 0.0188 0.0347 0.0487
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0045 0.0117
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0095 0.0285
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0044 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0019 0.0017
Mycobacterium leprae putative cytochrome p450 0.0212 0.0397 1
Schistosoma mansoni metabotropic glutamate receptor 0.0027 0.0011 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.077 0.1566 0.5015
Schistosoma mansoni protein kinase 0.0032 0.0021 0.0014
Echinococcus granulosus Immunoglobulin 0.0208 0.039 0.0548
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0191 0.0606
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0028 0.0071
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0208 0.039 0.0383
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0212 0.0397 0.1244
Echinococcus granulosus glutamate NMDA receptor subunit 0.0274 0.0527 0.0744
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0157 0.0282 0.0393
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0049 0.0134
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0095 0.0089
Leishmania major hypothetical protein, conserved 0.003 0.0017 0.0021
Echinococcus multilocularis receptor type guanylyl cyclase 0.0046 0.005 0.0062
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0052 0.0138
Trichomonas vaginalis glutaminase, putative 0.0281 0.0541 0.1794
Loa Loa (eye worm) hypothetical protein 0.006 0.008 0.0234
Schistosoma mansoni inositol monophosphatase 0.0038 0.0033 0.0026
Echinococcus granulosus chromobox protein 1 0.0073 0.0106 0.0142
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1448 0.2988 0.9585
Loa Loa (eye worm) hypothetical protein 0.0128 0.0222 0.0692
Echinococcus granulosus lachesin 0.0045 0.0049 0.006
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Echinococcus multilocularis glutamate receptor 2 0.0109 0.0182 0.0251
Echinococcus granulosus neuroglian 0.0045 0.0049 0.006
Loa Loa (eye worm) glutaminase 2 0.0281 0.0541 0.1719
Brugia malayi beta-lactamase family protein 0.0043 0.0045 0.0121
Echinococcus granulosus cytochrome P450 2K1 0.0212 0.0397 0.0558
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0032 0.0084
Schistosoma mansoni neuroglian 0.0045 0.0049 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Brugia malayi serine/threonine kinase 12 0.0483 0.0965 0.3081
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0045 0.0038
Onchocerca volvulus 0.0052 0.0062 0.0171
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0045 0.0391
Schistosoma mansoni roundabout 0.0045 0.0049 0.0042
Echinococcus granulosus metabotropic glutamate receptor 2 0.0027 0.0011 0.0006
Schistosoma mansoni tyrosine kinase 0.0064 0.0088 0.0082
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0212 0.0397 0.5755
Trypanosoma cruzi C-8 sterol isomerase, putative 0.151 0.3117 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0052 0.0152
Schistosoma mansoni chromobox protein 0.0073 0.0106 0.0099
Echinococcus granulosus glutamate receptor 2 0.0188 0.0347 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0052 0.0152
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0045 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0045 0.0109
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0191 0.0593
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0018 0.0038
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0212 0.0397 0.5755
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0265 0.0509 0.1614
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.004 0.0106
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0036 0.0041
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0018 0.0005
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0049 0.006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0095 0.0273
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0045 0.0537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0019 0.0012
Schistosoma mansoni protein kinase 0.0032 0.0021 0.0014
Echinococcus multilocularis tyrosine protein kinase otk 0.0045 0.0049 0.006
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0079 0.0118 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0483 0.0965 0.3216
Loa Loa (eye worm) hypothetical protein 0.0052 0.0062 0.0176
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0095 0.0306
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0045 0.0121
Loa Loa (eye worm) glutamate receptor 2 0.0161 0.029 0.091
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0095 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.1448 0.2988 1
Echinococcus multilocularis tyrosine kinase 0.0046 0.005 0.0062
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0191 0.0264
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0212 0.0397 0.7288
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0212 0.0397 0.1244
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0188 0.0347 0.0487
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0035 0.009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0045 0.0391
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0045 0.0049 0.0127
Mycobacterium ulcerans hypothetical protein 0.0043 0.0045 0.0184
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0483 0.0965 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0033 0.0089
Trypanosoma cruzi aurora B kinase, putative 0.0483 0.0965 0.3073
Echinococcus multilocularis glutamate receptor 2 0.0161 0.029 0.0405
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0018 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0212 0.0397 0.7288
Mycobacterium tuberculosis Conserved protein 0.0043 0.0045 0.0391
Echinococcus granulosus glutamate receptor 2 0.0109 0.0182 0.0251
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0078 0.0117 0.1809
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0045 0.0391
Leishmania major cytochrome p450-like protein 0.0212 0.0397 0.1244
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0111 0.0185 0.3149
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0045 0.0391
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0052 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0212 0.0397 0.7288
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0027 0.0011 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0037 0.0104
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Echinococcus multilocularis titin 0.0033 0.0023 0.0023
Chlamydia trachomatis glutamine binding protein 0.0078 0.0117 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0265 0.0509 0.1614
Echinococcus granulosus hemicentin 1 0.0045 0.0049 0.006
Trichomonas vaginalis AGC family protein kinase 0.0483 0.0965 0.3216
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0188 0.0347 0.0487
Schistosoma mansoni tyrosine kinase 0.0046 0.005 0.0044
Schistosoma mansoni hypothetical protein 0.0212 0.0397 0.039
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0188 0.0347 0.0487
Echinococcus granulosus twitchin 0.0241 0.0459 0.0647
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0027 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0012 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0027 0.0067
Brugia malayi Prion-like- 0.0045 0.0049 0.0134
Trypanosoma brucei protein kinase, putative 0.0032 0.0021 0.0066
Toxoplasma gondii ABC1 family protein 0.0043 0.0045 0.0288
Loa Loa (eye worm) CYP4Cod1 0.034 0.0665 0.2118
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.005 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0014 0.0025
Loa Loa (eye worm) cytochrome P450 0.0212 0.0397 0.1254
Schistosoma mansoni serine/threonine protein kinase 0.1448 0.2988 0.2983
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0095 0.0285
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0045 0.0054
Toxoplasma gondii aurora kinase 0.0483 0.0965 1
Schistosoma mansoni glutamate receptor kainate 0.0161 0.029 0.0283
Onchocerca volvulus 0.0032 0.002 0.0033
Onchocerca volvulus 0.0028 0.0012 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0318 0.1045
Loa Loa (eye worm) AUR protein kinase 0.0483 0.0965 0.3081
Schistosoma mansoni titin 0.0045 0.0049 0.0042
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0033 0.0072
Mycobacterium tuberculosis Conserved protein 0.0043 0.0045 0.0391
Brugia malayi beta-lactamase 0.0043 0.0045 0.0121
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0208 0.039 0.0548
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0052 0.0144
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0212 0.0397 0.7288
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0212 0.0397 0.5755
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0409 0.1292
Echinococcus multilocularis hemicentin 1 0.0045 0.0049 0.006
Echinococcus granulosus aurora kinase A 0.0483 0.0965 0.1372
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0121
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0212 0.0397 0.5755
Schistosoma mansoni cell adhesion molecule 0.0234 0.0443 0.0437
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0033 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0121
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0106 0.0318
Echinococcus granulosus roundabout 2 0.0045 0.0049 0.006
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0045 0.0391
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0033 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0023 0.0016
Echinococcus granulosus roundabout 2 0.0045 0.0049 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0483 0.0965 0.0959
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0062 0.0055
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0188 0.0347 0.0487
Entamoeba histolytica protein kinase, putative 0.0483 0.0965 0.3206
Brugia malayi Cytochrome P450 family protein 0.0212 0.0397 0.1254
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0191 0.0581
Entamoeba histolytica protein kinase , putative 0.0483 0.0965 0.3206
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0017 0.0021
Echinococcus granulosus receptor type guanylyl cyclase 0.0046 0.005 0.0062
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0018 0.0005
Brugia malayi follicle stimulating hormone receptor 0.0247 0.047 0.1491
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0033 0.0037
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0111 0.0185 0.3149
Brugia malayi Cytochrome P450 family protein 0.077 0.1566 0.5015
Echinococcus granulosus lamin 0.0028 0.0012 0.0007
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0012 0.0015
Echinococcus multilocularis roundabout 2 0.0045 0.0049 0.006
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0079 0.0118 0.0159
Trichomonas vaginalis CAMK family protein kinase 0.1448 0.2988 1
Plasmodium vivax SET domain protein, putative 0.0031 0.0019 0.0016
Mycobacterium tuberculosis Conserved protein 0.0043 0.0045 0.0391
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0055 0.0069
Trichomonas vaginalis esterase, putative 0.0043 0.0045 0.0128
Loa Loa (eye worm) cytochrome P450 family protein 0.034 0.0665 0.2118
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0212 0.0397 0.7288
Schistosoma mansoni glutamate receptor AMPA 0.0161 0.029 0.0283
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0212 0.0397 0.1274
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0212 0.0397 0.7288
Echinococcus granulosus tyrosine protein kinase otk 0.0045 0.0049 0.006
Brugia malayi serine/threonine-protein kinase plk-2 0.1448 0.2988 0.9585
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0049 0.0134
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0212 0.0397 0.7288
Schistosoma mansoni glutamate receptor kainate 0.0161 0.029 0.0283
Echinococcus multilocularis chromobox protein 1 0.0073 0.0106 0.0142
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0027 0.0011 0.0006
Echinococcus multilocularis musashi 0.0028 0.0012 0.0007
Onchocerca volvulus 0.0247 0.0472 0.1548
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.0211 0.5016
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.004 0.0033
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0032 0.0068
Loa Loa (eye worm) hypothetical protein 0.0208 0.039 0.1232
Onchocerca volvulus 0.0046 0.005 0.0133
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0212 0.0397 0.7288
Schistosoma mansoni glutamate receptor AMPA 0.0161 0.029 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0039 0.0109
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.047 0.1491
Brugia malayi Glutamate receptor 2 precursor 0.0161 0.029 0.091
Entamoeba histolytica protein kinase domain containing protein 0.0483 0.0965 0.3206
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0018 0.0038
Schistosoma mansoni protein kinase 0.0483 0.0965 0.0959
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0188 0.0347 0.0487
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0032 0.0021 0.0035
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0012 0.0015
Brugia malayi hypothetical protein 0.003 0.0017 0.0034
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0033 0.0106
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0212 0.0397 0.5755
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0039 0.0035 0.004
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0212 0.0397 0.5755
Schistosoma mansoni septate junction protein 0.0045 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0208 0.039 0.1232
Loa Loa (eye worm) hypothetical protein 0.0041 0.0039 0.0103
Loa Loa (eye worm) hypothetical protein 0.0234 0.0443 0.1403
Brugia malayi protein unc-22 0.0033 0.0023 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0212 0.0397 0.5755
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0191 0.0185
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0055 0.0069
Brugia malayi Fibronectin type III domain containing protein 0.0208 0.039 0.1232
Loa Loa (eye worm) hypothetical protein 0.0254 0.0485 0.1538
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0212 0.0397 0.7288
Brugia malayi Glutamate receptor 1 precursor 0.0161 0.029 0.091
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0509 0.1685
Echinococcus multilocularis nmda type glutamate receptor 0.0108 0.018 0.0248
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0045 0.0391
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0045 0.0128
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0212 0.0397 0.7288
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0509 0.1685
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0052 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0014 0.0025
Schistosoma mansoni tyrosine kinase 0.0046 0.005 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.1448 0.2988 1
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0483 0.0965 0.1372
Trichomonas vaginalis AGC family protein kinase 0.0483 0.0965 0.3216
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0212 0.0397 0.7288
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Loa Loa (eye worm) hypothetical protein 0.003 0.0017 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.1448 0.2988 1
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0045 0.0049 0.0042
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0483 0.0965 0.1372
Echinococcus multilocularis lamin dm0 0.0028 0.0012 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0052 0.0132
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0121
Giardia lamblia GTOR 0.0047 0.0052 0.0115
Echinococcus granulosus tyrosine kinase 0.0046 0.005 0.0062
Brugia malayi glutaminase DH11.1 0.0281 0.0541 0.1719
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0018 0.0024
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0212 0.0397 0.5755
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0033 0.0072
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0045 0.0184
Loa Loa (eye worm) hypothetical protein 0.0254 0.0485 0.1538
Loa Loa (eye worm) hypothetical protein 0.0208 0.039 0.1232
Echinococcus multilocularis NMDA receptor 0.0079 0.0118 0.0159
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0212 0.0397 0.7288
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0052 0.0144
Loa Loa (eye worm) beta-lactamase 0.0043 0.0045 0.0121
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0106 0.0333
Brugia malayi chromobox protein homolog 3 0.0041 0.0039 0.0103
Echinococcus granulosus titin 0.0033 0.0023 0.0023
Echinococcus granulosus tyrosine protein kinase Lyn 0.0032 0.0021 0.002
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.034 0.0665 1
Trichomonas vaginalis AGC family protein kinase 0.0483 0.0965 0.3216
Trypanosoma brucei cytochrome P450, putative 0.034 0.0665 0.2135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0012 0.0019
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0212 0.0397 0.1244
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0191 0.4475
Loa Loa (eye worm) glutaminase 0.0281 0.0541 0.1719
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0033 0.0075
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0052 0.0166
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0191 0.0593
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0045 0.0288
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.005
Trypanosoma brucei C-8 sterol isomerase, putative 0.151 0.3117 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0212 0.0397 0.7288
Trypanosoma brucei trypanothione reductase 0.0049 0.0055 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0509 0.1685
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0079 0.0118 0.0159
Echinococcus multilocularis Immunoglobulin 0.0208 0.039 0.0548
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0045 0.0143
Toxoplasma gondii cytochrome p450 superfamily protein 0.0212 0.0397 0.4006
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0016 0.0014
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0212 0.0397 0.5755
Brugia malayi Immunoglobulin I-set domain containing protein 0.0208 0.039 0.1232
Entamoeba histolytica protein kinase, putative 0.0483 0.0965 0.3206
Echinococcus granulosus titin 0.0033 0.0023 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0018 0.0038
Schistosoma mansoni metabotropic glutamate receptor 0.0027 0.0011 0.0004
Echinococcus multilocularis glutamate receptor NMDA 0.0081 0.0123 0.0166
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0052 0.0064
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0045 0.0391
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Brugia malayi serine/threonine-protein kinase 6 0.0483 0.0965 0.3081
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0036 0.0041
Schistosoma mansoni ATP-binding cassette transporter 0.0161 0.029 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0039 0.0109
Brugia malayi 6-phosphofructokinase 0.0113 0.0191 0.0593
Schistosoma mansoni hypothetical protein 0.0041 0.004 0.0033
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0846 0.1727 0.2462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0027 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0318 0.1045
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0483 0.0965 0.3206
Brugia malayi hypothetical protein 0.0027 0.0011 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0032 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0023 0.0016
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0032 0.0021 0.002
Schistosoma mansoni microtubule-associated protein tau 0.0708 0.1438 0.1432
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0033 0.0023 0.0051
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0052 0.0138
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0055 0.0143
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0212 0.0397 0.5755
Trypanosoma brucei aurora B kinase 0.0483 0.0965 0.3097
Loa Loa (eye worm) hypothetical protein 0.0046 0.005 0.014
Loa Loa (eye worm) CAMK protein kinase 0.0033 0.0023 0.0051
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0536 1
Leishmania major protein kinase, putative 0.0483 0.0965 0.3073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0032 0.0084
Leishmania major protein kinase, putative 0.0032 0.0021 0.0032
Echinococcus granulosus atrial natriuretic peptide receptor 0.0027 0.0011 0.0006
Onchocerca volvulus 0.0043 0.0045 0.0114
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0208 0.039 0.0383
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0212 0.0397 0.7288
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0318 0.1045
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0017 0.0055
Onchocerca volvulus Tyrosine kinase homolog 0.1198 0.2463 0.8236
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0318 0.1045
Entamoeba histolytica protein kinase domain containing protein 0.0032 0.0021 0.0033
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0033 0.0165
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0018 0.0005
Loa Loa (eye worm) AUR protein kinase 0.0483 0.0965 0.3081
Mycobacterium tuberculosis Probable reductase 0.0111 0.0185 0.3149
Trypanosoma cruzi polo-like protein kinase, putative 0.1448 0.2988 0.9584
Echinococcus granulosus peroxidasin 0.0045 0.0049 0.006
Trichomonas vaginalis CAMK family protein kinase 0.1448 0.2988 1
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0045 0.0049 0.006
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0032 0.0102
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0052 0.0166
Onchocerca volvulus Serine\/threonine kinase homolog 0.1448 0.2988 1
Loa Loa (eye worm) hypothetical protein 0.151 0.3117 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0055 0.0599
Entamoeba histolytica serine/threonine protein kinase, putative 0.1448 0.2988 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0045 0.0054
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0095 0.0127
Loa Loa (eye worm) hypothetical protein 0.0208 0.039 0.1232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0027 0.0067
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0052 0.0064
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0018 0.0038
Schistosoma mansoni hypothetical protein 0.0079 0.0118 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0045 0.0109
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0121
Brugia malayi Metabotropic glutamate receptor precursor. 0.0027 0.0011 0.0012
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0049 0.0134
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.0211 0.3655
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0191 0.0264
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0509 0.1685
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0191 0.0606
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0045 0.0128
Brugia malayi hypothetical protein 0.0208 0.039 0.1232
Giardia lamblia Kinase, PLK 0.1448 0.2988 1
Onchocerca volvulus Glucosylceramidase homolog 0.0174 0.0318 0.1032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0045 0.0121
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0018 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0023 0.0051
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0028 0.0071
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0212 0.0397 0.7288
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0212 0.0397 0.5755
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0483 0.0965 0.3206
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0019 0.0017
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0045 0.0184
Loa Loa (eye worm) hypothetical protein 0.0028 0.0012 0.0015
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0033 0.0084
Echinococcus multilocularis microtubule associated protein 2 0.0708 0.1438 0.2048
Mycobacterium ulcerans lipase LipD 0.0043 0.0045 0.0184
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0191 0.062
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1448 0.2988 0.4266
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0019 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0052 0.0045
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0191 1
Brugia malayi phosphofructokinase 0.0113 0.0191 0.0593
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0318 0.1045
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0078 0.0117 0.133
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0012 0.0017
Schistosoma mansoni titin 0.0033 0.0023 0.0016
Plasmodium falciparum protein kinase, putative 0.0032 0.0021 0.0035
Echinococcus granulosus glutamate receptor NMDA 0.0081 0.0123 0.0166
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.336 0.6993 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.008 0.0234
Schistosoma mansoni septate junction protein 0.0045 0.0049 0.0042
Plasmodium falciparum thioredoxin reductase 0.0049 0.0055 0.04
Echinococcus granulosus contactin 0.0045 0.0049 0.006
Echinococcus granulosus lamin dm0 0.0028 0.0012 0.0007
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0021 0.0032
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0033 0.5
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0045 0.0049 0.006
Leishmania major C-8 sterol isomerase-like protein 0.151 0.3117 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0027 0.0011 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0018 0.0038
Echinococcus multilocularis 0.0212 0.0397 0.0558
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0079 0.0118 0.0159
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0188 0.0347 0.0487
Schistosoma mansoni vesicular amine transporter 0.0211 0.0395 0.0389
Trichomonas vaginalis set domain proteins, putative 0.0247 0.0472 0.156
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Brugia malayi Cytochrome P450 family protein 0.034 0.0665 0.2118
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0019 0.0012
Schistosoma mansoni cell adhesion molecule 0.0045 0.0049 0.0042
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0049 0.006
Brugia malayi serine/threonine protein kinase 6 0.0483 0.0965 0.3081
Loa Loa (eye worm) inositol-1 0.0038 0.0033 0.0084
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0045 0.0128
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0033 0.0089
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0212 0.0397 0.7288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0027 0.0067
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0188 0.0347 0.0487
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0191 0.062
Onchocerca volvulus 0.0043 0.0044 0.0111
Brugia malayi glutathione reductase 0.0049 0.0055 0.0155
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0191 0.062
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0049 0.0134
Schistosoma mansoni chromobox protein 0.0073 0.0106 0.0099
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0039 0.0095
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0044
Loa Loa (eye worm) hypothetical protein 0.0772 0.157 0.5027
Schistosoma mansoni cell adhesion molecule 0.0045 0.0049 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0019 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0318 0.1045
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0338 0.1111
Schistosoma mansoni inositol monophosphatase 0.0038 0.0033 0.0026
Trypanosoma cruzi cytochrome P450, putative 0.034 0.0665 0.2108
Brugia malayi ERG2 and Sigma1 receptor like protein 0.151 0.3117 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0039 0.0035 0.009
Brugia malayi Thioredoxin reductase 0.0049 0.0055 0.0155
Brugia malayi Pre-SET motif family protein 0.0031 0.0019 0.0038
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0033 0.0037
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0212 0.0397 0.5755
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0095 0.0273
Brugia malayi Pre-SET motif family protein 0.0217 0.0409 0.1292
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0212 0.0397 0.1244
Schistosoma mansoni cell adhesion molecule 0.0045 0.0049 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.1411 0.2911 0.9337
Echinococcus multilocularis lamin 0.0028 0.0012 0.0007
Schistosoma mansoni cytochrome P450 0.0212 0.0397 0.039
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0052 0.0132
Onchocerca volvulus 0.0043 0.0045 0.0114
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0191 0.3261
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0483 0.0965 0.3206
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0111 0.0185 0.3149
Schistosoma mansoni glutamate receptor NMDA 0.0274 0.0527 0.052
Mycobacterium ulcerans glutaminase 0.0281 0.0541 0.8039
Brugia malayi Inositol-1 0.0038 0.0033 0.0084
Brugia malayi 6-phosphofructokinase 0.0113 0.0191 0.0593
Echinococcus multilocularis lachesin 0.0045 0.0049 0.006
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Brugia malayi cytochrome P450 0.0212 0.0397 0.1254
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0045 0.0131
Brugia malayi Guanylyl cyclase protein 23 0.0046 0.005 0.014
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0212 0.0397 0.7288
Mycobacterium tuberculosis Probable dehydrogenase 0.0111 0.0185 0.3149
Toxoplasma gondii thioredoxin reductase 0.0049 0.0055 0.04
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0052 0.0152
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0059 0.0076 0.0223
Echinococcus granulosus intermediate filament protein 0.0028 0.0012 0.0007
Echinococcus granulosus nmda type glutamate receptor 0.0237 0.0451 0.0635
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1448 0.2988 0.9584
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0106 0.0333
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0038
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1448 0.2988 0.4266
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0039 0.0035 0.004
Brugia malayi Peroxidasin 0.0045 0.0049 0.0134
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0027 0.0011 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.1448 0.2988 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0032 0.0084
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.0106
Schistosoma mansoni nephrin 0.0045 0.0049 0.0042
Brugia malayi metabotropic glutamate receptor type 2 0.0027 0.0011 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0212 0.0397 0.7288
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0212 0.0397 0.7288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0032 0.0084
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0234 0.0443 0.0625
Echinococcus granulosus tumor protein p63 0.0353 0.0693 0.0981
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0045 0.0128
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0212 0.0397 0.5755
Echinococcus granulosus neuroglian 0.0228 0.0432 0.0608
Loa Loa (eye worm) hypothetical protein 0.0045 0.0049 0.0134
Schistosoma mansoni glutamate receptor NMDA 0.0269 0.0516 0.051
Echinococcus multilocularis neuroglian 0.0045 0.0049 0.006
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0111 0.0185 0.432
Onchocerca volvulus 0.1159 0.2381 0.7963
Schistosoma mansoni glutaminase 0.0281 0.0541 0.0535
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0018 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0318 0.1045
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0045 0.0049 0.006
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0212 0.0397 0.5755
Echinococcus multilocularis activin receptor type 0.0032 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.1448 0.2988 1
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0012 0.0015
Echinococcus multilocularis aurora kinase A 0.0483 0.0965 0.1372
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0212 0.0397 0.5755
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0027 0.0011 0.0012
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0212 0.0397 0.5755
Echinococcus multilocularis hemicentin 1 0.0045 0.0049 0.006
Echinococcus granulosus activin receptor type 0.0032 0.0021 0.002
Echinococcus granulosus nmda type glutamate receptor 0.0108 0.018 0.0248
Brugia malayi Cytochrome P450 family protein 0.034 0.0665 0.2118
Brugia malayi Heterochromatin protein 1 0.0073 0.0106 0.0318
Echinococcus granulosus defective proboscis extension response 0.0208 0.039 0.0548
Echinococcus granulosus chromobox protein 1 0.0073 0.0106 0.0142
Leishmania major trypanothione reductase 0.0049 0.0055 0.0143
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.0509 0.1685
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0191 0.2503
Trypanosoma brucei polo-like protein kinase 0.1448 0.2988 0.9586
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0191 0.0581
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0046 0.005 0.0133
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0027 0.0098
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0212 0.0397 0.5755
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0027 0.0011 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0017 0.0036
Echinococcus multilocularis neuroglian 0.0228 0.0432 0.0608
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0021 0.0066
Trypanosoma cruzi polo-like protein kinase, putative 0.1448 0.2988 0.9584
Loa Loa (eye worm) hypothetical protein 0.0208 0.039 0.1232
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0019 0.0016
Echinococcus granulosus glutamate receptor subunit protein glur 0.0079 0.0118 0.0159

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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