Detailed information for compound 83297

Basic information

Technical information
  • TDR Targets ID: 83297
  • Name: 2-benzhydryl-7-hydroxychromen-4-one
  • MW: 328.361 | Formula: C22H16O3
  • H donors: 1 H acceptors: 2 LogP: 4.57 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1)oc(cc2=O)C(c1ccccc1)c1ccccc1
  • InChi: 1S/C22H16O3/c23-17-11-12-18-19(24)14-21(25-20(18)13-17)22(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-14,22-23H
  • InChiKey: VVMXRAGTHNZYRJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-benzhydryl-7-hydroxy-chromen-4-one
  • 2-benzhydryl-7-hydroxy-1-benzopyran-4-one
  • 2-benzhydryl-7-hydroxy-chromone
  • 2-[di(phenyl)methyl]-7-hydroxychromen-4-one
  • 2-[di(phenyl)methyl]-7-hydroxy-chromen-4-one
  • 2-[di(phenyl)methyl]-7-hydroxy-4-chromenone
  • 2-[di(phenyl)methyl]-7-hydroxy-chromone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bos taurus Aldose reductase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Entamoeba histolytica aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma cruzi aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans see also nonallelic CaP19.2244 Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans see also nonallelic CaP19.2244 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium tuberculosis Probable oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus hypothetical protein Get druggable targets OG5_126583 All targets in OG5_126583
Brugia malayi oxidoreductase, aldo/keto reductase family protein Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani prostaglandin f2-alpha synthase Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis dihydrodiol dehydrogenase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium ulcerans oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma japonicum ko:K00011 aldehyde reductase [EC1.1.1.21], putative Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma mansoni pol-related Get druggable targets OG5_126583 All targets in OG5_126583
Giardia lamblia Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei gambiense aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Giardia lamblia Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major aldehyde reductase, putative,oxidoreductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Entamoeba histolytica aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani aldehyde reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma cruzi aldo-keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium leprae Conserved hypothetical protein Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Mycobacterium leprae PROBABLE OXIDOREDUCTASE Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei prostaglandin f synthase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis dihydrodiol dehydrogenase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Entamoeba histolytica aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldehyde reductase Get druggable targets OG5_126583 All targets in OG5_126583
Toxoplasma gondii aldose reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
Neospora caninum Oxidoreductase, aldo/keto reductase family, related Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma japonicum IPR001395,Aldo/keto reductase,domain-containing Get druggable targets OG5_126583 All targets in OG5_126583
Onchocerca volvulus Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma congolense aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania infantum prostaglandin f2-alpha synthase/D-arabinose dehydrogenase Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis dihydrodiol dehydrogenase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldehyde reductase Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma mansoni aldo-keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans Aldose reductase Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo/keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania mexicana prostaglandin f2-alpha synthase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Loa Loa (eye worm) oxidoreductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania major aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
Trichomonas vaginalis aldo-keto reductase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Schistosoma mansoni aldo-keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Candida albicans similar to mammalian aldo/keto reductases Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma congolense prostaglandin f synthase, putative Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus multilocularis aldo keto reductase family 1, member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Echinococcus granulosus aldo keto reductase family 1 member B4 Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania braziliensis prostaglandin f2-alpha synthase/D-arabinose dehydrogenase Get druggable targets OG5_126583 All targets in OG5_126583
Trypanosoma brucei gambiense prostaglandin f synthase. putative Get druggable targets OG5_126583 All targets in OG5_126583
Leishmania donovani aldo-keto reductase-like protein Get druggable targets OG5_126583 All targets in OG5_126583
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans D-arabinose dehydrogenase, NADP-dependent Aldose reductase   315 aa 294 aa 35.4 %
Trypanosoma cruzi aldo/keto reductase, putative Aldose reductase   315 aa 304 aa 29.3 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   315 aa 319 aa 19.7 %
Onchocerca volvulus Aldose reductase   315 aa 316 aa 36.7 %
Toxoplasma gondii aldo/keto reductase family oxidoreductase Aldose reductase   315 aa 294 aa 24.8 %
Candida albicans D-arabinose dehydrogenase, NADP-dependent Aldose reductase   315 aa 294 aa 35.4 %
Candida albicans putative aryl alcohol dehydrogenase Aldose reductase   315 aa 326 aa 20.9 %
Candida albicans see also nonallelic CaP19.6816 Aldose reductase   315 aa 279 aa 29.7 %
Leishmania mexicana aldo/keto reductase, putative,aldo/keto reductase family-like protein Aldose reductase   315 aa 349 aa 25.2 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   315 aa 319 aa 18.2 %
Neospora caninum aldo/keto reductase family oxidoreductase, putative Aldose reductase   315 aa 291 aa 21.3 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   315 aa 319 aa 19.7 %
Candida albicans putative aryl alcohol dehydrogenase Aldose reductase   315 aa 310 aa 20.0 %
Candida albicans similar to putative aryl alcohol dehydrogenase family Aldose reductase   315 aa 314 aa 18.2 %
Mycobacterium ulcerans hypothetical protein Aldose reductase   315 aa 322 aa 24.8 %
Onchocerca volvulus Multiple coagulation factor deficiency protein 2 homolog Aldose reductase   315 aa 323 aa 40.2 %
Mycobacterium tuberculosis Conserved protein Aldose reductase   315 aa 323 aa 25.4 %
Candida albicans aryl alcohol dehydrogenase Aldose reductase   315 aa 319 aa 18.2 %
Candida albicans see also nonallelic CaP19.6816 Aldose reductase   315 aa 279 aa 29.7 %
Onchocerca volvulus Aldose reductase   315 aa 324 aa 39.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Dopamine receptor protein 1 0.0024 0.0072 0.0146
Echinococcus multilocularis netrin receptor unc 5 0.003 0.0146 0.0146
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.0059 0.0118
Schistosoma mansoni amine GPCR 0.0024 0.0072 0.0091
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0072 0.0146
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0072 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0048 0.0347 0.072
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0018 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0048 0.0347 0.072
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.001 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0502 0.3701
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Echinococcus granulosus importin subunit beta 1 0.0032 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus granulosus microtubule associated protein 2 0.07 0.7698 0.7698
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0214 0.0214
Brugia malayi RNA, U transporter 1 0.0091 0.0826 0.172
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0024 0.0078 0.0157
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.0059 0.0118
Echinococcus multilocularis transfer RNA-Gly 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Loa Loa (eye worm) ryanodine receptor 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Mycobacterium tuberculosis Conserved protein 0.004 0.0252 0.0932
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0347 0.072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus granulosus carbonic anhydrase II 0.0028 0.0122 0.0122
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0096 0.0889 0.1851
Echinococcus granulosus glycogen phosphorylase 0.0318 0.3391 0.3391
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.009 0.0114
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.011 0.0226
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0523 0.4111
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0494 0.1026
Echinococcus granulosus aldehyde reductase 0.0027 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0028 0.0122 0.025
Schistosoma mansoni biogenic amine receptor 0.0024 0.0072 0.0091
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0059 0.0074
Brugia malayi Cytochrome P450 family protein 0.0056 0.0439 0.0912
Echinococcus granulosus g protein coupled receptor 0.0024 0.0072 0.0072
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0072 0.0146
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0024 0.0078 0.0157
Echinococcus granulosus carbonic anhydrase 0.0028 0.0122 0.0122
Schistosoma mansoni intermediate filament proteins 0.0027 0.011 0.014
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Echinococcus multilocularis serotonin receptor 0.0024 0.0072 0.0072
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0038 0.0233 0.4623
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0024 0.0078 0.0304
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0072 0.0146
Echinococcus granulosus aldo keto reductase 0.0038 0.0233 0.0233
Plasmodium falciparum potassium channel 0.0024 0.0078 0.1008
Mycobacterium ulcerans oxidoreductase 0.0038 0.0233 0.171
Loa Loa (eye worm) hypothetical protein 0.0096 0.0889 0.1851
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Echinococcus granulosus potassium large conductance calcium activated 0.0018 0.0003 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Schistosoma mansoni carbonic anhydrase 0.0028 0.0122 0.0156
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0072 0.0072
Schistosoma mansoni cpg binding protein 0.0031 0.0149 0.0191
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus granulosus death domain containing protein 0.003 0.0146 0.0146
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.009 0.1197
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0396 0.4274 0.555
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0059 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0048 0.0347 0.072
Brugia malayi ORL1-like opioid receptor 0.0024 0.0072 0.0146
Brugia malayi Serotonin receptor 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0184
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Schistosoma mansoni voltage-gated potassium channel 0.0026 0.0098 0.0124
Schistosoma mansoni carbonic anhydrase-related 0.0028 0.0122 0.0156
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Onchocerca volvulus 0.0024 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus multilocularis twik family of potassium channels 0.0024 0.0078 0.0078
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Schistosoma mansoni neuropeptide receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) steroid hormone receptor 0.0048 0.0347 0.072
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0372 0.0773
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.0059 0.0059
Schistosoma mansoni ankyrin 23/unc44 0.003 0.0146 0.0187
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.01 0.0393
Echinococcus multilocularis lamin 0.0027 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0024 0.0072 0.0091
Onchocerca volvulus 0.0024 0.0072 0.0126
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.001 0.001
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0024 0.0078 0.0157
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.01 0.134
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0072 0.0072
Brugia malayi jmjC domain containing protein 0.006 0.0475 0.0987
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0072 0.0072
Echinococcus granulosus neuropeptide receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis shaker cognate 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Mycobacterium ulcerans ion transport protein 0.0024 0.0078 0.0557
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0072 0.0072
Brugia malayi tailless protein 0.0023 0.0059 0.0118
Onchocerca volvulus 0.0024 0.0072 0.0126
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0072 0.0091
Brugia malayi beta-lactamase 0.004 0.0252 0.052
Leishmania major prostaglandin f synthase, putative 0.0038 0.0233 0.4623
Mycobacterium tuberculosis Conserved protein 0.004 0.0252 0.0932
Schistosoma mansoni hypothetical protein 0.0018 0.0003 0.0001
Onchocerca volvulus 0.0029 0.013 0.0232
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0059 0.0074
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0059 0.0059
Schistosoma mansoni myosin xvIII 0.0024 0.0072 0.0091
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0451 0.3537
Schistosoma mansoni ran 0.0023 0.0067 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0026 0.0098 0.0124
Loa Loa (eye worm) uncoordinated protein 58 0.0024 0.0078 0.0157
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.049 0.049
Echinococcus granulosus cpg binding protein 0.0031 0.0149 0.0149
Brugia malayi conserved hypotetical protein 0.0023 0.0059 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0252 0.1005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0048 0.0347 0.072
Brugia malayi Cytochrome P450 family protein 0.0035 0.0198 0.0409
Echinococcus multilocularis aldo keto reductase 0.0038 0.0233 0.0233
Echinococcus multilocularis carbonic anhydrase 0.0028 0.0122 0.0122
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0028 0.0122 0.025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis transient receptor potential gamma protein 0.0018 0.0003 0.0003
Echinococcus granulosus g protein coupled receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis 0.0018 0.0002 0.0002
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0028 0.0122 0.0483
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0497 0.1849
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0497 0.0642
Brugia malayi ion channel NompC 0.0018 0.0003 0.0002
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0072 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0078 0.0304
Echinococcus multilocularis snurportin 1 0.0341 0.3647 0.3647
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0679 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0964 0.2008
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.003 0.0146 0.0146
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0525 0.0679
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0048 0.0347 0.0347
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0038 0.0233 0.0414
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Onchocerca volvulus 0.0024 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0035 0.0192 0.0396
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0038 0.0233 0.0483
Entamoeba histolytica aldose reductase, putative 0.0038 0.0233 0.066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0024 0.0078 0.0098
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Brugia malayi G-protein coupled receptor 0.0024 0.0072 0.0146
Echinococcus granulosus aldo keto reductase 0.0038 0.0233 0.0233
Echinococcus multilocularis serotonin receptor 0.0024 0.0072 0.0072
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0048 0.0347 0.0347
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0003 0.0003
Onchocerca volvulus 0.0024 0.0072 0.0126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0904 1 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0502 0.065
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0072 0.0072
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0252 0.0932
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0347 0.0347
Entamoeba histolytica hypothetical protein 0.0036 0.0213 0.0601
Echinococcus multilocularis musashi 0.0027 0.011 0.011
Brugia malayi putative neuropeptide receptor 0.0024 0.0072 0.0146
Schistosoma mansoni neuropeptide receptor 0.0024 0.0072 0.0091
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0006 0.0006
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0072 0.0091
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0497 0.3657
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0018 0.0003 0.0001
Onchocerca volvulus 0.0024 0.0072 0.0126
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0048 0.0347 0.0347
Onchocerca volvulus 0.0024 0.0078 0.0136
Loa Loa (eye worm) TWK-28 protein 0.0024 0.0078 0.0157
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0396 0.4274 0.4274
Schistosoma mansoni vesicular amine transporter 0.0018 0.0003 0.0001
Echinococcus multilocularis two pore calcium channel protein 1 0.0018 0.0003 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0156 0.1564 0.1564
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0252 0.0252
Brugia malayi beta-lactamase family protein 0.004 0.0252 0.052
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0094 0.0159
Giardia lamblia Hypothetical protein 0.0024 0.0078 0.0199
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0252 0.0324
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0059 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0036 0.0213 0.0274
Trypanosoma brucei calcium-activated potassium channel, putative 0.0024 0.0078 0.0304
Echinococcus multilocularis sex peptide receptor 0.0024 0.0072 0.0072
Schistosoma mansoni biogenic amine receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) norepinephrine transporter 0.0096 0.0889 0.1851
Schistosoma mansoni glycogen phosphorylase 0.0318 0.3391 0.4403
Entamoeba histolytica glycogen phosphorylase, putative 0.0138 0.1354 0.3974
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0238 0.2482 1
Brugia malayi Transient-receptor-potential like protein 0.0018 0.0003 0.0002
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0059 0.0059
Schistosoma mansoni histamine h1 receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Mycobacterium tuberculosis Conserved protein 0.004 0.0252 0.0932
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.0059 0.0118
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0048 0.0347 0.0347
Schistosoma mansoni sodium/chloride dependent transporter 0.0096 0.0889 0.1152
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0059 0.0472 0.085
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.083 0.1076
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.0059 0.0074
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0024 0.0078 0.0157
Echinococcus granulosus carbonic anhydrase 0.0028 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0359 0.3858 0.5009
Echinococcus granulosus dnaJ subfamily B 0.0415 0.4482 0.4482
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0048 0.0347 0.0347
Plasmodium falciparum importin beta, putative 0.0032 0.0162 0.227
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0502 0.1871
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0523 0.0677
Schistosoma mansoni amine GPCR 0.0024 0.0072 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0252 0.1005
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0059 0.0074
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0072 0.0091
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0072 0.0072
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0475 0.0475
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Brugia malayi Cyclic-nucleotide gated cation channel 0.0023 0.0059 0.0118
Schistosoma mansoni opsin-like receptor 0.0024 0.0072 0.0091
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0192 0.0396
Echinococcus granulosus neuropeptide receptor A26 0.0491 0.5337 0.5337
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0048 0.0347 0.072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Echinococcus granulosus intermediate filament protein 0.0027 0.011 0.011
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0003 0.0003
Brugia malayi hypothetical protein 0.0166 0.1669 0.3482
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0072 0.0072
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0018 0.0003 0.0003
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0018 0.0003 0.0002
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Schistosoma mansoni netrin receptor unc5 0.003 0.0146 0.0187
Echinococcus multilocularis flap endonuclease 1 0.0026 0.01 0.01
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0396 0.4274 0.4274
Brugia malayi Melatonin receptor type 1A 0.0024 0.0072 0.0146
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0198 0.0409
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0183
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0038 0.0233 0.0414
Loa Loa (eye worm) hypothetical protein 0.004 0.0252 0.052
Toxoplasma gondii transporter, cation channel family protein 0.013 0.127 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0024 0.0078 0.0157
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0252 0.0932
Onchocerca volvulus 0.0024 0.0078 0.0136
Entamoeba histolytica Flap nuclease, putative 0.0026 0.01 0.0265
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0028 0.0122 0.0483
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0439 0.0912
Onchocerca volvulus 0.0024 0.0072 0.0126
Brugia malayi cation channel family protein 0.0018 0.0003 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0048 0.0347 0.072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus multilocularis aldo keto reductase 0.0038 0.0233 0.0233
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0372 0.0773
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0059 0.0102
Mycobacterium ulcerans lipase LipD 0.004 0.0252 0.1844
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.01 0.1951
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.004 0.0252 0.052
Echinococcus granulosus ryanodine receptor 44f 0.0018 0.0003 0.0003
Loa Loa (eye worm) carbonic anhydrase 3 0.0028 0.0122 0.025
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0067 0.0848
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0679 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0494 0.0494
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0094 0.0159
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.009 0.0354
Echinococcus granulosus allatostatin A receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis geminin 0.0359 0.3858 0.3858
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0072 0.0072
Echinococcus granulosus carbonic anhydrase 0.0028 0.0122 0.0122
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0048 0.0347 0.072
Plasmodium vivax SET domain protein, putative 0.0064 0.0523 0.7676
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0048 0.0347 0.0448
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis dnaJ subfamily B 0.0415 0.4482 0.4482
Loa Loa (eye worm) calcium channel 0.0396 0.4274 0.8922
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0146 0.03
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0067 0.026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0233 0.0483
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0059 0.0059
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0497 0.39
Onchocerca volvulus Bile acid receptor homolog 0.0048 0.0347 0.0628
Schistosoma mansoni transient receptor potential channel 0.0018 0.0003 0.0001
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0233 0.0483
Schistosoma mansoni two-pore calcium channel 0.0018 0.0003 0.0001
Trypanosoma brucei carbonic anhydrase-like protein 0.0028 0.0122 0.0483
Echinococcus granulosus lamin 0.0027 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Brugia malayi Protein kinase domain containing protein 0.003 0.0146 0.03
Onchocerca volvulus Protein ultraspiracle homolog 0.0048 0.0347 0.0628
Echinococcus granulosus tumor protein p63 0.0343 0.3668 0.3668
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0026 0.0098 0.0098
Brugia malayi beta-lactamase family protein 0.004 0.0252 0.052
Schistosoma mansoni carbonic anhydrase-related 0.0028 0.0122 0.0156
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0475 0.0475
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.009 0.0693
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0396 0.4274 0.4274
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0028 0.0122 0.025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0198 0.0789
Loa Loa (eye worm) hypothetical protein 0.0048 0.0342 0.0709
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0072 0.0072
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0475 0.0475
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.0059 0.0074
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Brugia malayi AKH receptor 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Trichomonas vaginalis glycogen phosphorylase, putative 0.0318 0.3391 0.6185
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0072 0.0072
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0024 0.0078 0.0157
Onchocerca volvulus 0.0024 0.0078 0.0136
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0028 0.0122 0.025
Echinococcus granulosus hypothetical protein 0.0018 0.0003 0.0003
Brugia malayi larval opioid receptor 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0028 0.0122 0.025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0048 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis voltage dependent calcium channel 0.0396 0.4274 0.4274
Echinococcus granulosus serotonin receptor 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.1525 0.318
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0103 0.0961 0.2002
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0198 0.0789
Brugia malayi G protein-coupled receptor 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0133 0.0231
Echinococcus multilocularis ryanodine receptor 44f 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0048 0.0347 0.0347
Brugia malayi hypothetical protein 0.0026 0.009 0.0184
Brugia malayi hypothetical protein 0.0023 0.0059 0.0118
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.009 0.0354
Echinococcus granulosus aldo keto reductase 0.0038 0.0233 0.0233
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0067 0.0135
Loa Loa (eye worm) serotonin transporter b 0.0096 0.0889 0.1851
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0213 0.0213
Echinococcus granulosus hypothetical protein 0.0038 0.0233 0.0233
Brugia malayi carbohydrate phosphorylase 0.0318 0.3391 0.7078
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0497 0.0642
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0347 0.072
Brugia malayi Importin beta-1 subunit 0.0032 0.0162 0.0333
Schistosoma mansoni glycogen phosphorylase 0.0138 0.1354 0.1756
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0198 0.0409
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0091 0.083 0.1076
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Brugia malayi steroid hormone receptor 0.0048 0.0347 0.072
Onchocerca volvulus 0.0024 0.0078 0.0136
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0023 0.0059 0.0059
Brugia malayi nuclear receptor RXR 0.0026 0.009 0.0183
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0347 0.072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0027 0.0105 0.0214
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0076 0.0654 0.0847
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.0059 0.0118
Echinococcus multilocularis potassium large conductance calcium activated 0.0018 0.0003 0.0003
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0072 0.0072
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.0059 0.0118
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.0059 0.0118
Schistosoma mansoni ap endonuclease 0.0018 0.001 0.001
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0042 0.0052
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0368 0.0475
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0059 0.0074
Leishmania major cytochrome p450-like protein 0.0018 0.0002 0.0003
Onchocerca volvulus 0.0038 0.0233 0.042
Loa Loa (eye worm) hypothetical protein 0.013 0.127 0.2647
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0072 0.0072
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0415 0.4482 0.5821
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Leishmania major cytochrome p450-like protein 0.0035 0.0198 0.3917
Echinococcus granulosus sex peptide receptor 0.0024 0.0072 0.0072
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.0003 0.0002
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Brugia malayi hypothetical protein 0.0036 0.0213 0.0441
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0252 0.0932
Entamoeba histolytica hypothetical protein 0.0036 0.0213 0.0601
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0072 0.0072
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0072 0.0091
Mycobacterium tuberculosis Probable oxidoreductase 0.0038 0.0233 0.0865
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0072 0.0146
Toxoplasma gondii hypothetical protein 0.0018 0.0003 0.0007
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Onchocerca volvulus 0.0024 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0183
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0072 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0347 0.0448
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0035 0.0192 0.0246
Loa Loa (eye worm) hypothetical protein 0.0112 0.1068 0.2226
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Onchocerca volvulus 0.005 0.0368 0.0665
Schistosoma mansoni 60S ribosomal protein L21 0.0021 0.0042 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0214 0.1565
Echinococcus granulosus sodium channel protein 0.0018 0.0003 0.0003
Echinococcus multilocularis small conductance calcium activated potassium 0.0024 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0138 0.1354 0.5056
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0112 0.1068 0.2226
Loa Loa (eye worm) intermediate filament protein 0.0027 0.011 0.0226
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0032 0.0223
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0122 0.025
Onchocerca volvulus 0.0038 0.0233 0.042
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0497 0.3657
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0198 0.1449
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0162 0.0644
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0072 0.0146
Onchocerca volvulus 0.0024 0.0078 0.0136
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0125 0.1216 0.1216
Echinococcus multilocularis glycogen phosphorylase 0.0318 0.3391 0.3391
Schistosoma mansoni steroid hormone receptor ad4bp 0.0048 0.0347 0.0448
Echinococcus granulosus two pore calcium channel protein 2 0.0018 0.0003 0.0003
Trypanosoma cruzi aldo/keto reductase, putative 0.0038 0.0233 0.0932
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.0078 0.0098
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0032 0.0113
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.0059 0.0059
Onchocerca volvulus 0.0024 0.0072 0.0126
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0026 0.0098 0.0199
Echinococcus multilocularis thyroid hormone receptor alpha 0.0048 0.0347 0.0347
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0018 0.0003 0.0022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0059 0.0096
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0028 0.0122 0.025
Trypanosoma brucei prostaglandin f synthase 0.0038 0.0233 0.0932
Brugia malayi PAS domain containing protein 0.0049 0.0358 0.0744
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0396 0.4274 0.4274
Brugia malayi nuclear hormone receptor 0.0023 0.0059 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0347 0.0347
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0078 0.013
Loa Loa (eye worm) oxidoreductase 0.0038 0.0233 0.0483
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0003 0.0001
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0067 0.0848
Loa Loa (eye worm) hypothetical protein 0.0096 0.0889 0.1851
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0048 0.0347 0.072
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.0059 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0059 0.0059
Echinococcus granulosus twik family of potassium channels 0.0024 0.0078 0.0078
Brugia malayi nuclear receptor NHR-88 0.0023 0.0059 0.0118
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0252 0.0324
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0347 0.0448
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Mycobacterium ulcerans hypothetical protein 0.002 0.0032 0.0223
Onchocerca volvulus 0.0103 0.0961 0.1748
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.0059 0.0074
Leishmania major hypothetical protein, unknown function 0.0018 0.0003 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0048 0.0347 0.072
Trichomonas vaginalis glycogen phosphorylase, putative 0.0318 0.3391 0.6185
Brugia malayi neuropeptide F receptor 0.0024 0.0072 0.0146
Echinococcus granulosus voltage gated hydrogen channel 1 0.0018 0.0003 0.0003
Echinococcus multilocularis carbonic anhydrase II 0.0028 0.0122 0.0122
Entamoeba histolytica aldose reductase, putative 0.0038 0.0233 0.066
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0059 0.0059
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Brugia malayi nuclear receptor NHR-67 0.0023 0.0059 0.0118
Echinococcus granulosus short transient receptor potential channel 6 0.0018 0.0003 0.0003
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0072 0.0072
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.0059 0.0118
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0023 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Schistosoma mansoni single-minded 0.0049 0.0358 0.0463
Loa Loa (eye worm) hypothetical protein 0.004 0.0252 0.052
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0213 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0347 0.072
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.001 0.001
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0024 0.0078 0.0078
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.001 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0347 0.0347
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.01 0.0393
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0396 0.4274 0.4274
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0372 0.0773
Brugia malayi GnHR receptor homolog 0.0024 0.0072 0.0146
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0018 0.0003 0.0002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0024 0.0078 0.0157
Schistosoma mansoni nuclear receptor 0.0023 0.0059 0.0074
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0072 0.0146
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0067 0.026
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0018 0.0003 0.0003
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0059 0.0118
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0252 0.0447
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.001 0.0032
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0502 0.1044
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0183
Echinococcus multilocularis glycogen phosphorylase 0.0318 0.3391 0.3391
Schistosoma mansoni RAR-like nuclear receptor 0.0048 0.0347 0.0448
Onchocerca volvulus 0.0024 0.0072 0.0126
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0347 0.072
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0162 0.0644
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0003 0.0003
Onchocerca volvulus 0.004 0.0252 0.0453
Plasmodium vivax potassium channel, putative 0.0024 0.0078 0.1008
Loa Loa (eye worm) hypothetical protein 0.0026 0.0098 0.0199
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0059 0.0059
Schistosoma mansoni voltage-gated potassium channel 0.0056 0.0436 0.0564
Loa Loa (eye worm) voltage-dependent calcium channel 0.013 0.127 0.2647
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0024 0.0078 0.1508
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.009 0.009
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Onchocerca volvulus 0.0024 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.003 0.0146 0.03
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.003 0.0146 0.0146
Onchocerca volvulus 0.0096 0.0889 0.1616
Trichomonas vaginalis ran, putative 0.0023 0.0067 0.011
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0059 0.0059
Schistosoma mansoni voltage-gated ion channel 0.0018 0.0003 0.0001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0094 0.0369
Echinococcus granulosus hypothetical protein 0.0024 0.0072 0.0072
Echinococcus multilocularis sodium channel protein 0.0125 0.1216 0.1216
Leishmania major cytochrome p450-like protein 0.0018 0.0002 0.0003
Schistosoma mansoni amine GPCR 0.0024 0.0072 0.0091
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0252 0.0932
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Brugia malayi hypoxia-induced factor 1 0.0153 0.1525 0.318
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0072 0.0146
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Brugia malayi sulfakinin receptor protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Mycobacterium leprae Conserved hypothetical protein 0.0027 0.0108 0.1568
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0497 0.9884
Schistosoma mansoni jumonji domain containing protein 0.006 0.0475 0.0614
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0072 0.0072
Loa Loa (eye worm) ion channel NompC 0.0018 0.0003 0.0002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0048 0.0347 0.0448
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.009 0.1197
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0255 0.2675 1
Leishmania major importin beta-1 subunit, putative 0.0026 0.0094 0.1832
Echinococcus multilocularis neuropeptide s receptor 0.0491 0.5337 0.5337
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0003 0.0003
Brugia malayi Uncoordinated protein 44 0.003 0.0146 0.03
Brugia malayi Cytochrome P450 family protein 0.0035 0.0198 0.0409
Echinococcus granulosus geminin 0.0359 0.3858 0.3858
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0059 0.0074
Loa Loa (eye worm) hypothetical protein 0.004 0.0252 0.052
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0048 0.0347 0.0448
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.001 0.0032
Toxoplasma gondii hypothetical protein 0.0112 0.1068 0.841
Echinococcus granulosus Glycosyl transferase family 35 0.0318 0.3391 0.3391
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.0003 0.0002
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0053 0.0398 0.0826
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0096 0.0889 0.1152
Brugia malayi follicle stimulating hormone receptor 0.0257 0.2705 0.5644
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Trichomonas vaginalis aldo/keto reductase, putative 0.0038 0.0233 0.0414
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0003 0.0003
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.01 0.0265
Brugia malayi neuropeptide F receptor 0.0024 0.0072 0.0146
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0252 0.0447
Brugia malayi olfactory channel protein osm-9 0.0018 0.0006 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0146 0.03
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0032 0.0053
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0072 0.0146
Schistosoma mansoni neuropeptide receptor 0.0024 0.0072 0.0091
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0059 0.0074
Schistosoma mansoni glycogen phosphorylase 0.0318 0.3391 0.4403
Echinococcus multilocularis voltage dependent calcium channel 0.0396 0.4274 0.4274
Echinococcus granulosus serotonin transporter 0.0096 0.0889 0.0889
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0003 0.0003
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0078 0.0304
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0018 0.0003 0.0002
Toxoplasma gondii ABC1 family protein 0.004 0.0252 0.1966
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0226
Echinococcus multilocularis two pore calcium channel protein 2 0.0018 0.0003 0.0003
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0252 0.1844
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0072 0.0072
Onchocerca volvulus Netrin receptor homolog 0.003 0.0146 0.026
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0072 0.0091
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0679 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Echinococcus granulosus TRP transient receptor potential channel 0.0018 0.0003 0.0003
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0024 0.0078 0.0157
Loa Loa (eye worm) oxidoreductase 0.0038 0.0233 0.0483
Brugia malayi G-protein coupled receptor 0.0024 0.0072 0.0146
Loa Loa (eye worm) beta-lactamase 0.004 0.0252 0.052
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0003 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Entamoeba histolytica hypothetical protein 0.0036 0.0213 0.0601
Brugia malayi hypothetical protein 0.0024 0.0078 0.0157
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0059 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0048 0.0347 0.0347
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0059 0.0096
Brugia malayi Serotonin receptor 0.0024 0.0072 0.0146
Plasmodium falciparum carbonic anhydrase 0.0028 0.0122 0.1675
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.001 0.016
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0003 0.0003
Toxoplasma gondii hypothetical protein 0.0018 0.0003 0.0007
Schistosoma mansoni lamin 0.0027 0.011 0.014
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0038 0.0233 0.4623
Trypanosoma brucei aldo-keto reductase, putative 0.0038 0.0233 0.0932
Schistosoma mansoni calcium-activated potassium channel 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.0078 0.0098
Brugia malayi RE15519p 0.0024 0.0072 0.0146
Echinococcus multilocularis short transient receptor potential channel 6 0.0018 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Brugia malayi nuclear receptor NHR-88 0.0048 0.0347 0.072
Leishmania major GTP-binding protein, putative 0.0023 0.0067 0.1293
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0059 0.0472 0.085
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0252 0.1005
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.009 0.0183
Brugia malayi hypothetical protein 0.0018 0.0003 0.0002
Onchocerca volvulus 0.0023 0.0059 0.0102
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0072 0.0091
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0018 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0024 0.0078 0.0098
Echinococcus granulosus small conductance calcium activated potassium 0.0024 0.0078 0.0078
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0072 0.0091
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0059 0.0102
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) TWK-7 protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) voltage-gated calcium channel 0.0018 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0359 0.3858 0.5009
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.001 0.0032
Echinococcus granulosus potassium channel subfamily K 8 0.0024 0.0078 0.0078
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Plasmodium vivax importin-beta 2, putative 0.0032 0.0162 0.227
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Giardia lamblia Aldose reductase 0.0038 0.0233 0.066
Plasmodium falciparum potassium channel 0.0024 0.0078 0.1008
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Schistosoma mansoni cpg binding protein 0.0031 0.0149 0.0191
Toxoplasma gondii exonuclease III APE 0.0018 0.001 0.0062
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0018 0.0003 0.0022
Echinococcus multilocularis voltage gated potassium channel 0.0026 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Brugia malayi nuclear receptor RXR 0.0023 0.0059 0.0118
Echinococcus granulosus two pore calcium channel protein 1 0.0018 0.0003 0.0003
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0679 0.1413
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Toxoplasma gondii ion channel protein 0.0024 0.0078 0.0594
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0024 0.0078 0.0078
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0028 0.0122 0.0156
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0048 0.0347 0.0628
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0023 0.0059 0.0059
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0198 0.0789
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0252 0.1844
Echinococcus granulosus glycogen phosphorylase 0.0318 0.3391 0.3391
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0072 0.0146
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0072 0.0091
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0072 0.0072
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0018 0.0003 0.0002
Echinococcus multilocularis FTZ F1 alpha 0.0048 0.0347 0.0347
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0198 0.0409
Echinococcus granulosus fmrfamide receptor 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0048 0.0347 0.072
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0053 0.0398 0.0398
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0003 0.0001
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0018 0.0003 0.0001
Schistosoma mansoni aldo-keto reductase 0.0038 0.0233 0.03
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.001 0.0058
Echinococcus granulosus neuropeptide receptor 0.0024 0.0072 0.0072
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0358 0.0463
Echinococcus multilocularis somatostatin receptor 0.0024 0.0072 0.0072
Brugia malayi Flap endonuclease-1 0.0026 0.01 0.0203
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0233 0.0483
Leishmania major carbonic anhydrase-like protein 0.0028 0.0122 0.2399
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0072 0.0072
Brugia malayi Dopamine receptor protein 2 0.0024 0.0072 0.0146
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0072 0.0146
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0072 0.0072
Brugia malayi Pre-SET motif family protein 0.0442 0.479 1
Echinococcus multilocularis calcium activated potassium channel variant 0.0024 0.0078 0.0078
Mycobacterium leprae conserved hypothetical protein 0.004 0.0252 0.3683
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Schistosoma mansoni coup transcription factor 0.0048 0.0347 0.0448
Schistosoma mansoni aldo-keto reductase 0.0038 0.0233 0.03
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0396 0.4274 0.4274
Onchocerca volvulus 0.0024 0.0078 0.0136
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0003 0.0003
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0502 0.0502
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.009 0.1197
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Onchocerca volvulus 0.0038 0.0233 0.042
Leishmania major potassium channel subunit-like protein 0.0024 0.0078 0.1508
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0166 0.1669 0.3482
Loa Loa (eye worm) oxidoreductase 0.0038 0.0233 0.0483
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0024 0.0078 0.0157
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0094 0.0159
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0059 0.0059
Schistosoma mansoni biogenic amine receptor 0.0024 0.0072 0.0091
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0162 0.0162
Schistosoma mansoni hypothetical protein 0.0052 0.0394 0.0508
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.01 0.0203
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0048 0.0347 0.072
Onchocerca volvulus 0.0027 0.011 0.0195
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0252 0.052
Schistosoma mansoni microtubule-associated protein tau 0.07 0.7698 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0024 0.0078 0.0157
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0059 0.0118
Entamoeba histolytica aldose reductase, putative 0.0038 0.0233 0.066
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0018 0.0003 0.0002
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0072 0.0146
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0072 0.0072
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0018 0.0003 0.0001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0497 0.0497
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0072 0.0091
Echinococcus multilocularis carbonic anhydrase 0.0028 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0024 0.0072 0.0091
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0523 0.0523
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0059 0.0074
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0396 0.4274 0.555
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0072 0.0091
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0024 0.0078 0.0304
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus granulosus shaker cognate 0.0018 0.0003 0.0003
Brugia malayi cation channel family protein 0.0018 0.0003 0.0002
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0028 0.0122 0.025
Giardia lamblia Aldose reductase 0.0038 0.0233 0.066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Onchocerca volvulus 0.0024 0.0072 0.0126
Mycobacterium ulcerans epimerase 0.002 0.0032 0.0223
Onchocerca volvulus 0.0027 0.011 0.0195
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0048 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0183
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0059 0.0074
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0523 0.0677
Schistosoma mansoni carbonic anhydrase-related 0.0028 0.0122 0.0156
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.0072 0.0072
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0024 0.0078 0.0157
Loa Loa (eye worm) solute carrier family 6 member 4 0.0096 0.0889 0.1851
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Schistosoma mansoni hypothetical protein 0.0341 0.3647 0.4736
Brugia malayi nuclear hormone receptor 0.0048 0.0347 0.072
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0024 0.0078 0.0304
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0252 0.052
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0072 0.0091
Echinococcus granulosus ecdysone induced protein 78C 0.0048 0.0347 0.0347
Schistosoma mansoni ryanodine receptor related 0.0018 0.0003 0.0001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0072 0.0072
Plasmodium falciparum flap endonuclease 1 0.0026 0.01 0.134
Echinococcus granulosus netrin receptor unc 5 0.003 0.0146 0.0146
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.001 0.5
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0024 0.0078 0.0157
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0072 0.0072
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Entamoeba histolytica Ran family GTPase 0.0023 0.0067 0.0168
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0023 0.0059 0.0059
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0018 0.0003 0.0002
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0238 0.2482 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0502 0.3701
Echinococcus multilocularis conserved hypothetical protein 0.0018 0.0003 0.0003
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0003 0.0003
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0024 0.0078 0.0157
Toxoplasma gondii ion channel protein 0.0024 0.0078 0.0594
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Mycobacterium ulcerans beta-lactamase 0.004 0.0252 0.1844
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0679 0.2531
Echinococcus granulosus neuropeptide s receptor 0.0491 0.5337 0.5337
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0502 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Onchocerca volvulus 0.004 0.0252 0.0453
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0024 0.0078 0.0157
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0072 0.0072
Echinococcus granulosus orexin receptor type 2 0.0024 0.0072 0.0072
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.009 0.0114
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0072 0.0072
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.005 0.0368 0.0763
Brugia malayi photoreceptor-specific nuclear receptor 0.0048 0.0347 0.072
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0053 0.0398 0.0398
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0067 0.0067
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0024 0.0078 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0048 0.0347 0.072
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0252 0.0932
Schistosoma mansoni hypothetical protein 0.0024 0.0072 0.0091
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0072 0.0072
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0018 0.0003 0.0003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0067 0.026
Entamoeba histolytica glycogen phosphorylase, putative 0.0318 0.3391 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.013 0.0267
Entamoeba histolytica hypothetical protein 0.0036 0.0213 0.0601
Echinococcus multilocularis ecdysone induced protein 78C 0.0048 0.0347 0.0347
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0072 0.0072
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0502 0.0502
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Onchocerca volvulus 0.0503 0.5481 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0072 0.0146
Plasmodium vivax potassium channel, putative 0.0024 0.0078 0.1008
Schistosoma mansoni pol-related 0.0038 0.0233 0.03
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0214 0.0442
Echinococcus granulosus twik family of potassium channels 0.0024 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0051 0.0372 0.0773
Echinococcus granulosus voltage dependent calcium channel 0.0396 0.4274 0.4274
Loa Loa (eye worm) hypothetical protein 0.004 0.0252 0.052
Onchocerca volvulus 0.0024 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0024 0.0078 0.0157
Onchocerca volvulus 0.0024 0.0072 0.0126
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0091 0.083 0.083
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0003 0.0003
Schistosoma mansoni retinoic acid receptor RXR 0.0048 0.0347 0.0448
Brugia malayi Death domain containing protein 0.003 0.0146 0.03
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0091 0.083 0.083
Brugia malayi hypothetical protein 0.0023 0.0059 0.0118
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0252 0.0447
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0003 0.0003
Onchocerca volvulus 0.0048 0.0347 0.0628
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0072 0.0091
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Brugia malayi intermediate filament protein 0.0027 0.011 0.0226
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0003 0.0007
Mycobacterium leprae Probable lipase LipE 0.004 0.0252 0.3683
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0032 0.0063
Brugia malayi voltage-dependent calcium channel 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0024 0.0078 0.0304
Trichomonas vaginalis aldo/keto reductase, putative 0.0038 0.0233 0.0414
Onchocerca volvulus 0.0024 0.0078 0.0136
Echinococcus granulosus transient receptor potential gamma protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Schistosoma mansoni voltage-dependent calcium channel 0.0018 0.0003 0.0001
Echinococcus multilocularis twik family of potassium channels 0.0024 0.0078 0.0078
Schistosoma mansoni neuropeptide receptor 0.0024 0.0072 0.0091
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0048 0.0347 0.0448
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Schistosoma mansoni flap endonuclease-1 0.0024 0.0071 0.0089
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Trichomonas vaginalis set domain proteins, putative 0.0503 0.5478 1
Leishmania major ion transport protein-like protein 0.0024 0.0078 0.1508
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0026 0.0098 0.0098
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0162 0.1259
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0396 0.4274 0.4274
Schistosoma mansoni cpg binding protein 0.0029 0.013 0.0166
Plasmodium vivax hypothetical protein, conserved 0.004 0.0252 0.3609
Echinococcus multilocularis tumor protein p63 0.0343 0.3668 0.3668
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Mycobacterium ulcerans endonuclease IV 0.0078 0.0679 0.5006
Brugia malayi ecdysteroid receptor 0.0048 0.0347 0.072
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0257 0.2705 0.5644
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0048 0.0347 0.072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Toxoplasma gondii aldose reductase, putative 0.0038 0.0233 0.1823
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0038 0.0233 0.0483
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Brugia malayi M-phase phosphoprotein, mpp8 0.0103 0.0961 0.2002
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Brugia malayi hypothetical protein 0.0103 0.0964 0.2008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0072 0.0072
Brugia malayi hypothetical protein 0.0024 0.0078 0.0157
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0072 0.0072
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0024 0.0078 0.0199
Trypanosoma cruzi aldo-keto reductase 0.0038 0.0233 0.0932
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0003 0.0003
Echinococcus multilocularis Ankyrin 0.0031 0.0149 0.0149
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.0003 0.0002
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0414 0.086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0523 0.0677
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0347 0.0448
Onchocerca volvulus 0.0024 0.0078 0.0136
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0072 0.0072
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0072 0.0091
Echinococcus multilocularis potassium channel subfamily K 0.0024 0.0078 0.0078
Schistosoma mansoni amine GPCR 0.0376 0.4043 0.5251
Onchocerca volvulus 0.0038 0.0233 0.042
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0067 0.0067
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0072 0.0146
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0059 0.0059
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Echinococcus multilocularis potassium channel subfamily K 8 0.0024 0.0078 0.0078
Brugia malayi Steroid receptor seven-up type 2 0.0048 0.0347 0.072
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0018 0.0003 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0523 0.0523
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0213 0.0274
Schistosoma mansoni opsin-like receptor 0.0024 0.0072 0.0091
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0072 0.0072
Schistosoma mansoni transient receptor potential channel 0.0018 0.0003 0.0001
Echinococcus granulosus FTZ F1 alpha 0.0048 0.0347 0.0347
Onchocerca volvulus 0.0076 0.0654 0.1188
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0347 0.072
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0072 0.0091
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.0059 0.0059
Echinococcus multilocularis aldo keto reductase 0.0038 0.0233 0.0233
Echinococcus multilocularis sodium leak channel non selective protein 0.0018 0.0003 0.0003
Loa Loa (eye worm) DR-78 0.0023 0.0059 0.0118
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0038 0.0233 0.0414
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.011 0.0226
Schistosoma mansoni opsin-like receptor 0.0024 0.0072 0.0091
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Schistosoma mansoni zinc finger protein 0.0023 0.0059 0.0074
Echinococcus granulosus Ankyrin 0.0031 0.0149 0.0149
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0003 0.0003
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.0072 0.0072
Mycobacterium ulcerans hypothetical protein 0.004 0.0252 0.1844
Echinococcus multilocularis Glycosyl transferase, family 35 0.0318 0.3391 0.3391
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0003 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0072 0.0072
Brugia malayi hypothetical protein 0.0026 0.009 0.0183
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0038 0.0233 0.3416
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Onchocerca volvulus 0.0038 0.0233 0.042
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0018 0.0003 0.0002
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0006 0.0006
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0063
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis microtubule associated protein 2 0.07 0.7698 0.7698
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Loa Loa (eye worm) oxidoreductase 0.0038 0.0233 0.0483
Echinococcus granulosus g protein coupled receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis calcium activated potassium channel 0.0018 0.0003 0.0003
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0023 0.0059 0.0059
Onchocerca volvulus 0.004 0.0252 0.0453
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0028 0.0122 0.0156
Echinococcus granulosus single minded 2 0.004 0.0253 0.0253
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.01 0.017
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0072 0.0146
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0252 0.0932
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0072 0.0146
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0024 0.0078 0.0078
Mycobacterium leprae conserved hypothetical protein 0.002 0.0032 0.0445
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0018 0.0003 0.0003
Trichomonas vaginalis esterase, putative 0.004 0.0252 0.0447
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0067 0.0168
Schistosoma mansoni ap endonuclease 0.0018 0.001 0.001
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0028 0.0122 0.025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0048 0.0347 0.072
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Echinococcus granulosus potassium channel subfamily K 8 0.0024 0.0078 0.0078
Echinococcus multilocularis carbonic anhydrase 0.0028 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0031 0.0149 0.0306
Loa Loa (eye worm) hypothetical protein 0.0032 0.0162 0.0333
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0183
Echinococcus granulosus calcium activated potassium channel variant 0.0024 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0078 0.0679 0.1413
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.0072 0.0126
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.001 0.0016
Schistosoma mansoni nuclear receptor 0.0023 0.0059 0.0074
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0003 0.0003
Trypanosoma cruzi ion transport protein, putative 0.0024 0.0078 0.0304
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0059 0.0059
Giardia lamblia Glycogen phosphorylase 0.0318 0.3391 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Schistosoma mansoni transient receptor potential channel 4 0.0018 0.0003 0.0001
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0396 0.4274 0.8922
Trichomonas vaginalis aldo/keto reductase, putative 0.0038 0.0233 0.0414
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0252 0.0932
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0494 0.0638
Schistosoma mansoni hypothetical protein 0.003 0.0146 0.0187
Loa Loa (eye worm) oxidoreductase 0.0038 0.0233 0.0483
Onchocerca volvulus 0.0024 0.0072 0.0126
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0494 0.0638
Onchocerca volvulus 0.0023 0.0059 0.0102
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0028 0.0122 0.0156
Brugia malayi Dopamine receptor 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0024 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0002 0.0002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0024 0.0078 0.0157
Brugia malayi CXXC zinc finger family protein 0.0029 0.013 0.0267
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Schistosoma mansoni transient receptor potential channel 0.0018 0.0006 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0252 0.0447
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0003 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0056 0.0436 0.0564
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0523 0.0523
Echinococcus granulosus sodium leak channel non selective protein 0.0018 0.0003 0.0003
Echinococcus granulosus somatostatin receptor 0.0024 0.0072 0.0072
Leishmania major calcium/potassium channel (CAKC), putative 0.0024 0.0078 0.1508
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0252 0.0447
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0067 0.0135
Toxoplasma gondii hypothetical protein 0.0028 0.0122 0.0946
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0003 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0497 0.3657
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0347 0.072
Onchocerca volvulus 0.0038 0.0233 0.042
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0072 0.0072
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0003 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.009 0.0183
Echinococcus granulosus flap endonuclease 1 0.0026 0.01 0.01
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0149 0.019
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0024 0.0078 0.0282
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0018 0.0003 0.0002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0003 0.0007
Leishmania major hypothetical protein, conserved 0.0024 0.0078 0.1508
Loa Loa (eye worm) hypothetical protein 0.004 0.0252 0.052
Brugia malayi Pre-SET motif family protein 0.0064 0.0523 0.1088
Schistosoma mansoni importin beta-1 0.0032 0.0162 0.0207
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Echinococcus granulosus voltage dependent calcium channel 0.013 0.127 0.127
Schistosoma mansoni adenoreceptor 0.0024 0.0072 0.0091
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0003 0.0003
Onchocerca volvulus 0.0024 0.0072 0.0126
Schistosoma mansoni amine GPCR 0.0024 0.0072 0.0091
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0059 0.0059
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0138 0.1354 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0072 0.0072
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0003 0.0003
Echinococcus granulosus snurportin 1 0.0341 0.3647 0.3647
Entamoeba histolytica hypothetical protein 0.0026 0.0094 0.0247
Schistosoma mansoni ran 0.0023 0.0067 0.0084
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0118
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0028 0.0122 0.025
Brugia malayi hypothetical protein 0.0024 0.0072 0.0146
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0067 0.0509
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0053 0.0398 0.0826
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Trichomonas vaginalis aldo-keto reductase, putative 0.0038 0.0233 0.0414
Echinococcus granulosus nuclear factor of activated T cells 5 0.0156 0.1564 0.1564
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0028 0.0122 0.025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0072 0.0091
Chlamydia trachomatis glycogen phosphorylase 0.0318 0.3391 1
Trypanosoma cruzi ion transport protein, putative 0.0024 0.0078 0.0304
Echinococcus multilocularis lamin dm0 0.0027 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0072 0.0072
Echinococcus multilocularis aldehyde reductase 0.0027 0.0108 0.0108
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.009 0.0183
Echinococcus granulosus short transient receptor potential channel 6 0.0018 0.0006 0.0006
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.0059 0.0059
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0341 0.3647 0.7612
Toxoplasma gondii endonuclease IV APN 0.0078 0.0679 0.5337
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.001 0.0016
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0072 0.0146
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0072 0.0072
Leishmania major hypothetical protein, conserved 0.0026 0.009 0.176
Brugia malayi hypothetical protein 0.0026 0.009 0.0183
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0072 0.0072
Onchocerca volvulus Glycogen phosphorylase homolog 0.0318 0.3391 0.6185
Brugia malayi jmjC domain containing protein 0.0061 0.0494 0.1026
Mycobacterium ulcerans transmembrane cation transporter 0.0024 0.0078 0.0557
Leishmania major aldo-keto reductase-like protein 0.0038 0.0233 0.4623
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0096 0.0889 0.1851
Echinococcus granulosus lamin dm0 0.0027 0.011 0.011
Echinococcus multilocularis neuropeptide receptor A26 0.0491 0.5337 0.5337
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Echinococcus multilocularis aldo keto reductase 0.0038 0.0233 0.0233
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.01 0.0769
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0072 0.0146
Schistosoma mansoni voltage-gated cation channel 0.0396 0.4274 0.555
Onchocerca volvulus 0.0024 0.0072 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Loa Loa (eye worm) hypothetical protein 0.0048 0.0347 0.072
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0497 0.0497
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0072 0.0072
Echinococcus granulosus potassium channel subfamily K 0.0024 0.0078 0.0078
Echinococcus granulosus voltage gated potassium channel 0.0026 0.0098 0.0098
Entamoeba histolytica glycogen phosphorylase, putative 0.0138 0.1354 0.3974
Schistosoma mansoni thyroid hormone receptor 0.0048 0.0347 0.0448
Brugia malayi ecdysone receptor 0.0023 0.0059 0.0118
Treponema pallidum sodium- and chloride- dependent transporter 0.0096 0.0889 1
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0078 0.0098
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0028 0.0122 0.025
Echinococcus multilocularis potassium channel subfamily K 8 0.0024 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0002
Loa Loa (eye worm) glycogen phosphorylase 0.0318 0.3391 0.7078
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0038 0.0233 0.0233
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0024 0.0078 0.0304
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0003 0.0007
Entamoeba histolytica glycogen phosphorylase, putative 0.0318 0.3391 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0048 0.0347 0.0448
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0442 0.479 1
Onchocerca volvulus 0.0103 0.0961 0.1748
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Schistosoma mansoni hypothetical protein 0.0024 0.0072 0.0091
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0347 0.0347
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.0059 0.0059
Echinococcus granulosus calcium activated potassium channel 0.0018 0.0003 0.0003
Echinococcus multilocularis short transient receptor potential channel 6 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Entamoeba histolytica glycogenphosphorylase, putative 0.0138 0.1354 0.3974
Onchocerca volvulus 0.0037 0.0214 0.0384
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0029 0.0133 0.0231
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.0078 0.0098
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0018 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0157
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0072 0.0072
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0072 0.0146
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.009 0.0354
Loa Loa (eye worm) hypothetical protein 0.0024 0.0072 0.0146
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0018 0.0003 0.0004
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0024 0.0078 0.0078
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0396 0.4274 0.8922
Loa Loa (eye worm) hypothetical protein 0.0064 0.0523 0.1088
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0038 0.0233 0.0233
Schistosoma mansoni lamin 0.0027 0.011 0.014
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0003 0.0001
Echinococcus multilocularis serotonin transporter 0.0096 0.0889 0.0889
Echinococcus multilocularis cpg binding protein 0.0031 0.0149 0.0149
Leishmania major hypothetical protein, conserved 0.004 0.0252 0.4984

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 10.89 uM Inhibition of Aldose reductase 2 of bovine lens ChEMBL. 10354396
IC50 (binding) = 10.89 uM Inhibition of Aldose reductase 2 of bovine lens ChEMBL. 10354396

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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