Detailed information for compound 999060

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 428.91 | Formula: C26H21ClN2O2
  • H donors: 1 H acceptors: 2 LogP: 6.01 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cc2nc([nH]c2cc1c1ccccc1)[C@@H]1CC[C@]2(CC1)OC(=O)c1c2cccc1
  • InChi: 1S/C26H21ClN2O2/c27-21-15-23-22(14-19(21)16-6-2-1-3-7-16)28-24(29-23)17-10-12-26(13-11-17)20-9-5-4-8-18(20)25(30)31-26/h1-9,14-15,17H,10-13H2,(H,28,29)/t17-,26-
  • InChiKey: GJAIVYBZNPYODK-PJCCXEONSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens neuropeptide Y receptor Y5 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Onchocerca volvulus 0.0133 0.0615 0.5237
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.0157 0.0291
Loa Loa (eye worm) norepinephrine transporter 0.006 0.023 0.0628
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0099 0.0434 0.0639
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0651 0.0958
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0651 0.0958
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0023 0.0033
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Trypanosoma cruzi hexose transporter, putative 0.0064 0.0254 0.0692
Trichomonas vaginalis sugar transporter, putative 0.0142 0.0657 0.2861
Echinococcus multilocularis histidyl tRNA synthetase 0.0015 0 0.0001
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0026 0.0038
Treponema pallidum glycyl-tRNA synthetase 0.0015 0 0.0015
Echinococcus multilocularis fmrfamide receptor 0.002 0.0023 0.0033
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0026 0.0054 0.1193
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0071 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.003 0.0078 0.0214
Trichomonas vaginalis esterase, putative 0.0036 0.0106 0.0463
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0023 0.0033
Echinococcus multilocularis cpg binding protein 0.0098 0.043 0.0633
Loa Loa (eye worm) acetyltransferase 0.0169 0.0801 0.2182
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0023 0.0033
Echinococcus granulosus General substrate transporter 0.0392 0.1961 0.2888
Onchocerca volvulus 0.006 0.023 0.1838
Echinococcus multilocularis solute carrier family 22 0.0064 0.0254 0.0374
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.006 0.023 0.0339
Onchocerca volvulus 0.0036 0.0106 0.0739
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0023 0.0033
Echinococcus granulosus g-protein coupled receptor 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0088 0.0385
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0179 0.027
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0064 0.0254 0.0692
Giardia lamblia Glycyl-tRNA synthetase 0.0026 0.0054 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0106 0.029
Leishmania major threonyl-tRNA synthetase, putative 0.0026 0.0054 0.0146
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0023 0.0033
Trypanosoma brucei histidyl-tRNA synthetase 0.0015 0 0.0001
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0178 0.0486
Plasmodium falciparum calcium-dependent protein kinase 4 0.014 0.0648 0.0648
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Schistosoma mansoni neuropeptide receptor 0.002 0.0023 0.0033
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0178 0.0486
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Loa Loa (eye worm) hypothetical protein 0.0026 0.0054 0.0146
Echinococcus multilocularis g protein coupled receptor 0.002 0.0023 0.0033
Echinococcus multilocularis sex peptide receptor 0.002 0.0023 0.0033
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.014 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0036 0.0106 0.029
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Plasmodium falciparum calcium-dependent protein kinase 1 0.014 0.0648 0.0648
Trypanosoma brucei glucose transporter 1E 0.0142 0.0657 0.1789
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.0054 0.0146
Leishmania major myo-inositol/proton symporter (MIT) 0.0064 0.0254 0.0692
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0023 0.0042
Brugia malayi jmjC domain containing protein 0.0025 0.0049 0.0133
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.016 0.0751 0.2046
Schistosoma mansoni biogenic amine receptor 0.002 0.0023 0.0033
Toxoplasma gondii sugar transporter ST3 0.0064 0.0254 0.0383
Schistosoma mansoni opsin-like receptor 0.002 0.0023 0.0033
Brugia malayi G-protein coupled receptor 0.002 0.0023 0.0062
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0106 0.0156
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.014 0.0648 0.0648
Plasmodium vivax calcium-dependent protein kinase, putative 0.014 0.0648 0.0648
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0102 0.045 1
Trypanosoma cruzi Emopamil binding protein, putative 0.0133 0.0615 0.1675
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1285 0.5597
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0023 0.0033
Onchocerca volvulus Putative transporter 0.0064 0.0254 0.2047
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0657 0.2861
Echinococcus granulosus tumor protein p63 0.0394 0.1973 0.2906
Schistosoma mansoni hypothetical protein 0.0029 0.0071 0.0104
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0026 0.0038
Treponema pallidum sodium- and chloride- dependent transporter 0.006 0.023 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0122 0.0333
Schistosoma mansoni sugar transporter 0.0064 0.0254 0.0374
Giardia lamblia Lysyl-tRNA synthetase 0.0102 0.045 0.0831
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Echinococcus multilocularis RUN 0.002 0.0026 0.0038
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0106 0.029
Leishmania major hypothetical protein, conserved 0.0025 0.0049 0.0133
Plasmodium vivax threonine--tRNA ligase, putative 0.0026 0.0054 0.0054
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0046 0.0067
Echinococcus multilocularis chromobox protein 1 0.0069 0.028 0.0413
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.014 0.0647 0.1764
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0086 0.037 0.5587
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0106 0.236
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0068 0.0276 0.0753
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0043 0.0948
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Schistosoma mansoni sugar transporter 0.0064 0.0254 0.0374
Loa Loa (eye worm) acetylcholinesterase 1 0.0068 0.0276 0.0753
Loa Loa (eye worm) latrophilin receptor protein 2 0.0099 0.0434 0.1182
Mycobacterium ulcerans lipase LipD 0.0036 0.0106 0.236
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.0033
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0026 0.0054 0.0234
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0065 0.0258 0.0704
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0106 0.029
Echinococcus multilocularis fmrfamide receptor 0.002 0.0023 0.0033
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0026 0.0054 0.0146
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0179 0.078
Echinococcus granulosus solute carrier family 22 0.0064 0.0254 0.0374
Loa Loa (eye worm) hypothetical protein 0.0029 0.0071 0.0192
Loa Loa (eye worm) hypothetical protein 0.0111 0.0499 0.136
Trypanosoma cruzi hexose transporter, putative 0.0142 0.0657 0.1789
Loa Loa (eye worm) hypothetical protein 0.0239 0.1163 0.3169
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0552 0.0813
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0023 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0023 0.0033
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0106 0.0903
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0137 0.0633 0.0932
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0023 0.0033
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0023 0.0033
Echinococcus multilocularis lysyl tRNA synthetase 0.0102 0.045 0.0663
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trypanosoma cruzi glucose transporter, putative 0.0064 0.0254 0.0692
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0023 0.0979
Echinococcus granulosus solute carrier family 22 0.0064 0.0254 0.0374
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0085 0.0125
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.016 0.0751 0.2046
Loa Loa (eye worm) hypothetical protein 0.006 0.023 0.0628
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0049 0.0072
Trichomonas vaginalis glucose transporter, putative 0.0064 0.0254 0.1107
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0043 0.0116
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0049 0.0072
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0023 0.0098
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Plasmodium vivax SET domain protein, putative 0.0032 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0142 0.0657 0.2861
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0815 0.3553
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0088 0.0385
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0023 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0023 0.0033
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0049 0.0133
Onchocerca volvulus 0.0064 0.0254 0.2047
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Echinococcus granulosus g protein coupled receptor 0.002 0.0023 0.0033
Loa Loa (eye worm) serotonin transporter b 0.006 0.023 0.0628
Giardia lamblia Prolyl-tRNA synthetase 0.0137 0.0633 0.1168
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0023 0.0033
Trichomonas vaginalis chromobox protein, putative 0.0069 0.028 0.1221
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Trichomonas vaginalis glucose transporter, putative 0.0142 0.0657 0.2861
Schistosoma mansoni biogenic amine receptor 0.002 0.0023 0.0033
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0075 0.011
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0007 0.001
Trypanosoma brucei C-8 sterol isomerase, putative 0.072 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0036 0.0053
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Brugia malayi follicle stimulating hormone receptor 0.0712 0.3626 0.9881
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0064 0.0254 1
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0049 0.0072
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0071 0.0106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0023 0.0033
Trypanosoma cruzi hexose transporter, putative 0.0142 0.0657 0.1789
Echinococcus granulosus allatostatin A receptor 0.002 0.0023 0.0033
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0064 0.0254 0.5643
Plasmodium falciparum mitogen-activated protein kinase 2 0.0737 0.3758 0.3758
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0651 0.1773
Schistosoma mansoni polycystin 1-related 0.002 0.0026 0.0038
Onchocerca volvulus 0.0064 0.0254 0.2047
Schistosoma mansoni lipoxygenase 0.0085 0.0362 0.0533
Onchocerca volvulus 0.0064 0.0254 0.2047
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Schistosoma mansoni opsin-like receptor 0.002 0.0023 0.0033
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0075 0.011
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.1163 0.1713
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.007
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0012 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0088 0.0385
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.0034
Brugia malayi jmjC domain containing protein 0.0152 0.0714 0.1945
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.003 0.0076 0.0113
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Schistosoma mansoni ap endonuclease 0.002 0.0023 0.0033
Loa Loa (eye worm) major facilitator superfamily transporter 0.0064 0.0254 0.0692
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1109 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0737 0.3758 0.5668
Echinococcus multilocularis GPCR, family 2 0.0099 0.0434 0.0639
Toxoplasma gondii glycyl-tRNA synthetase 0.0026 0.0054 0.0081
Trypanosoma cruzi hexose transporter 0.0142 0.0657 0.1789
Leishmania major histidyl-tRNA synthetase, putative 0.0015 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Trichomonas vaginalis myo-inositol transporter, putative 0.0064 0.0254 0.1107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.014 0.0647 0.0953
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0063 0.0275
Echinococcus granulosus geminin 0.103 0.5281 0.7778
Brugia malayi ERG2 and Sigma1 receptor like protein 0.072 0.3669 1
Onchocerca volvulus 0.0064 0.0254 0.2047
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0456 0.2295 0.338
Onchocerca volvulus 0.0237 0.1153 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.0064 0.0254 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0122 0.0532
Echinococcus multilocularis solute carrier family 22 0.0064 0.0254 0.0374
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0137 0.0598
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0023 0.0033
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0179 0.027
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0023 0.0033
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0102 0.045 0.1227
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0023 0.0062
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0023 0.0061
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0071 0.0104
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0023 0.0033
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.4181 0.6158
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0086 0.037 0.3297
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0456 0.2295 0.338
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0122 0.0879
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0026 0.0054 0.0146
Brugia malayi Carboxylesterase family protein 0.0068 0.0276 0.0753
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0099 0.0434 0.1182
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0036 0.0106 0.029
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0133 0.0615 0.1675
Loa Loa (eye worm) hypothetical protein 0.005 0.0178 0.0486
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0015 0 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0043 0.0948
Echinococcus granulosus chromobox protein 1 0.0069 0.028 0.0413
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0026 0.0054 0.0426
Schistosoma mansoni rab6-interacting 0.002 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.0213 0.103 0.2807
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0023 0.0033
Trypanosoma cruzi histidyl-tRNA synthetase 0.0015 0 0.0001
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0137 0.0633 0.1724
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0106 0.0463
Schistosoma mansoni hypothetical protein 0.0099 0.0434 0.0639
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0164
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0099 0.0434 0.0639
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Brugia malayi Dopamine receptor protein 1 0.002 0.0023 0.0062
Toxoplasma gondii sugar transporter ST2 0.0064 0.0254 0.0383
Brugia malayi Cam kinase protein 1 0.014 0.0647 0.1764
Onchocerca volvulus 0.0049 0.0174 0.1335
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0023 0.0033
Schistosoma mansoni biogenic amine receptor 0.002 0.0023 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0312 0.1544 0.4207
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0651 0.0958
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0043 0.0116
Echinococcus granulosus neuropeptide receptor 0.002 0.0023 0.0033
Schistosoma mansoni rab6-interacting 0.002 0.0026 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0651 0.0958
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0133 0.0615 0.1675
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0023 0.0062
Onchocerca volvulus 0.0064 0.0254 0.2047
Plasmodium vivax JmjC domain containing protein 0.0025 0.0049 0.0049
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.056 0.1526
Loa Loa (eye worm) solute carrier family 6 member 4 0.006 0.023 0.0628
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0023 0.0062
Echinococcus granulosus glycyl tRNA synthetase 0.0026 0.0054 0.0079
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0058 0.0221 0.0601
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.014 0.0647 0.0953
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0133 0.0615 0.1675
Schistosoma mansoni neuropeptide receptor 0.002 0.0023 0.0033
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0049 0.0072
Loa Loa (eye worm) hypothetical protein 0.0068 0.0276 0.0753
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0043 0.0948
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0043 0.0079
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0023 0.0033
Schistosoma mansoni lysyl-tRNA synthetase 0.0102 0.045 0.0663
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0254 0.1107
Echinococcus granulosus histone acetyltransferase KAT2B 0.0164 0.0776 0.1143
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0026 0.0054 0.0081
Leishmania major hypothetical protein, conserved 0.0064 0.0254 0.0692
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0137 0.0633 0.2756
Plasmodium falciparum phd finger protein, putative 0.0029 0.0071 0.0071
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0023 0.0033
Schistosoma mansoni amine GPCR 0.002 0.0023 0.0033
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0023 0.0033
Plasmodium falciparum proline--tRNA ligase 0.016 0.0751 0.0751
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0102 0.045 0.1227
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0043 0.0326
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0137 0.0633 0.1724
Toxoplasma gondii anticodon binding domain-containing protein 0.0015 0 0.0001
Brugia malayi Sugar transporter family protein 0.0064 0.0254 0.0692
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0737 0.3758 0.3758
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0049 0.0072
Loa Loa (eye worm) jmjC domain-containing protein 0.0098 0.0431 0.1174
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0106 0.0156
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0085 0.0125
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0023 0.0033
Leishmania major hypothetical protein, conserved 0.0023 0.0038 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0026 0.0026
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0012 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0815 0.3553
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Giardia lamblia Hexose transporter 0.0064 0.0254 0.0469
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0023 0.0033
Brugia malayi Serotonin receptor 0.002 0.0023 0.0062
Brugia malayi sulfakinin receptor protein 0.002 0.0023 0.0062
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0012 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0106 0.0106
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0038 0.0285
Schistosoma mansoni hypothetical protein 0.0049 0.0174 0.0256
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0651 0.0958
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0099 0.0434 0.0639
Echinococcus granulosus g protein coupled receptor 0.002 0.0023 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Echinococcus granulosus lysyl tRNA synthetase 0.0102 0.045 0.0663
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.014 0.0647 0.0953
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0015 0 0.0001
Brugia malayi hypothetical protein 0.0064 0.0254 0.0692
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0178 0.0178
Schistosoma mansoni loxhd1 0.002 0.0026 0.0038
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0015 0 0.0001
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0026 0.0054 0.0099
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Leishmania major glucose transporter, lmgt2 0.0142 0.0657 0.1789
Echinococcus granulosus serotonin receptor 0.002 0.0023 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0144 0.0212
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0023 0.0033
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0064 0.0254 0.0254
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0032
Echinococcus multilocularis chromobox protein 1 0.0069 0.028 0.0413
Onchocerca volvulus 0.0043 0.0144 0.107
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0049 0.0072
Schistosoma mansoni cpg binding protein 0.0093 0.0402 0.0593
Brugia malayi CXXC zinc finger family protein 0.0093 0.0402 0.1097
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0026 0.0054 0.0146
Schistosoma mansoni glucose transport protein 0.0456 0.2295 0.338
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0102 0.045 1
Brugia malayi hypothetical protein 0.0064 0.0254 0.0692
Schistosoma mansoni hypothetical protein 0.103 0.5281 0.7778
Brugia malayi Sodium:neurotransmitter symporter family protein 0.006 0.023 0.0628
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0099 0.0434 0.0639
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Plasmodium vivax CDK-related protein kinase 6, putative 0.1937 1 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0106 0.029
Schistosoma mansoni histidyl-tRNA synthetase 0.0015 0 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0137 0.0633 0.0932
Echinococcus granulosus acetylcholinesterase 0.0068 0.0276 0.0407
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0023 0.0033
Loa Loa (eye worm) sugar transporter 0.0456 0.2295 0.6255
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0064 0.0254 0.2243
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0049 0.0072
Echinococcus multilocularis glycyl tRNA synthetase 0.0026 0.0054 0.0079
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0015 0 0.0002
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.0033
Schistosoma mansoni protein kinase 0.014 0.0647 0.0953
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0178 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0254 0.1107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0651 0.0958
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Brugia malayi Serotonin receptor 0.002 0.0023 0.0062
Echinococcus granulosus histidyl tRNA synthetase 0.0015 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0032
Plasmodium vivax hexose transporter 0.0456 0.2295 0.2295
Schistosoma mansoni amine GPCR 0.002 0.0023 0.0033
Treponema pallidum threonyl-tRNA synthetase 0.0026 0.0054 0.2331
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1285 0.5597
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0106 0.029
Schistosoma mansoni sodium/chloride dependent transporter 0.006 0.023 0.0339
Leishmania major glucose transporter/membrane transporter D2, putative 0.0142 0.0657 0.1789
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0023 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.003 0.0129
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.0815 0.7014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0023 0.0061
Echinococcus multilocularis acetylcholinesterase 0.0068 0.0276 0.0407
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0179 0.0264
Mycobacterium tuberculosis Conserved protein 0.0036 0.0106 0.0903
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0166
Onchocerca volvulus 0.0064 0.0254 0.2047
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0071 0.0104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0023 0.0033
Onchocerca volvulus 0.0064 0.0254 0.2047
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0049 0.0072
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0043 0.0948
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0023 0.0033
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0023 0.0033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0088 0.0385
Entamoeba histolytica hypothetical protein 0.0102 0.045 0.0831
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0312 0.1544 0.4207
Echinococcus granulosus dnaJ subfamily B 0.132 0.679 1
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0064 0.0254 0.0374
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0864 0.3763
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0023 0.0023
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0012 0.026
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.014 0.0648 0.0977
Brugia malayi beta-lactamase 0.0036 0.0106 0.029
Schistosoma mansoni protein kinase 0.014 0.0647 0.0953
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0049 0.0133
Onchocerca volvulus 0.003 0.0078 0.0493
Echinococcus granulosus chromobox protein 1 0.0069 0.028 0.0413
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0023 0.0033
Echinococcus granulosus synaptic vesicle 2 protein 0.0064 0.0254 0.0374
Toxoplasma gondii histone lysine methyltransferase SET1 0.0181 0.0861 0.1299
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0023 0.0033
Brugia malayi chromobox protein homolog 3 0.0039 0.0122 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Schistosoma mansoni glucose transporter 0.0064 0.0254 0.0374
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0053
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0023 0.0033
Brugia malayi jmjC domain containing protein 0.0025 0.0049 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0023 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0088 0.0385
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0023 0.0033
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0026 0.0054 0.0146
Toxoplasma gondii ABC1 family protein 0.0036 0.0106 0.016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0116
Onchocerca volvulus 0.0064 0.0254 0.2047
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Brugia malayi major facilitator superfamily protein 0.0064 0.0254 0.0692
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0815 0.3553
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Plasmodium falciparum calcium-dependent protein kinase 3 0.014 0.0648 0.0648
Loa Loa (eye worm) doublecortin family protein 0.002 0.0026 0.007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0106 0.029
Schistosoma mansoni neuropeptide receptor 0.002 0.0023 0.0033
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0023 0.0062
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0068 0.0101
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0106 0.0156
Brugia malayi hypothetical protein 0.005 0.0178 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0166
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Echinococcus multilocularis geminin 0.103 0.5281 0.7778
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0023 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0647 0.0953
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0026 0.0054 0.0146
Echinococcus multilocularis g protein coupled receptor 0.002 0.0023 0.0033
Leishmania major hypothetical protein, conserved 0.0133 0.0615 0.1675
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0023 0.0033
Echinococcus granulosus neuropeptide s receptor 0.002 0.0023 0.0033
Toxoplasma gondii protein kinase, putative 0.1289 0.663 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Plasmodium vivax proline--tRNA ligase, putative 0.016 0.0751 0.0751
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0085 0.0125
Loa Loa (eye worm) major facilitator superfamily transporter 0.0064 0.0254 0.0692
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Echinococcus multilocularis peregrin 0.0033 0.0092 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0254 0.1107
Loa Loa (eye worm) hypothetical protein 0.0102 0.045 0.1227
Plasmodium vivax sugar transporter, putative 0.0064 0.0254 0.0254
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0026 0.0054 0.0099
Onchocerca volvulus 0.0064 0.0254 0.2047
Onchocerca volvulus 0.0064 0.0254 0.2047
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0102 0.045 0.1962
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.014 0.0647 0.1764
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0023 0.0062
Schistosoma mansoni lipoxygenase 0.0121 0.0552 0.0813
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0106 0.0156
Onchocerca volvulus 0.002 0.0026 0.0027
Loa Loa (eye worm) beta-lactamase 0.0036 0.0106 0.029
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Trypanosoma cruzi sugar transporter, putative 0.0064 0.0254 0.0692
Onchocerca volvulus 0.0064 0.0254 0.2047
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.014 0.0647 0.0953
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Plasmodium vivax glycine--tRNA ligase, putative 0.0026 0.0054 0.0054
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0015 0 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0106 0.0463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.072 0.3669 1
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0815 0.3553
Echinococcus granulosus RUN 0.002 0.0026 0.0038
Trypanosoma cruzi hexose transporter, putative 0.0077 0.0323 0.0879
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0651 0.0958
Trichomonas vaginalis set domain proteins, putative 0.0237 0.1153 0.5023
Brugia malayi Heterochromatin protein 1 0.0069 0.028 0.0764
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.014 0.0647 0.0953
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trypanosoma brucei glucose transporter 2A 0.0142 0.0657 0.1789
Loa Loa (eye worm) carboxylesterase 0.0068 0.0276 0.0753
Brugia malayi Pre-SET motif family protein 0.0032 0.0085 0.0231
Brugia malayi lysyl-tRNA synthetase 0.0102 0.045 0.1227
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0049 0.0049
Echinococcus granulosus neuropeptide receptor A26 0.002 0.0023 0.0033
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0106 0.0903
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0552 0.0813
Brugia malayi hypothetical protein 0.0032 0.0087 0.0237
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0023 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Brugia malayi jmjC domain containing protein 0.0025 0.0049 0.0133
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0023 0.0888
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0043 0.0326
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0086 0.037 0.3297
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0023 0.0061
Schistosoma mansoni hypothetical protein 0.0099 0.0434 0.0639
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0032
Toxoplasma gondii exonuclease III APE 0.002 0.0023 0.0034
Brugia malayi RE15519p 0.002 0.0023 0.0062
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0049 0.0133
Brugia malayi Major Facilitator Superfamily protein 0.0064 0.0254 0.0692
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0049 0.0074
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0056 0.0213 0.0579
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0064 0.0254 0.5643
Schistosoma mansoni ap endonuclease 0.002 0.0023 0.0033
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0106 0.0463
Echinococcus granulosus serotonin transporter 0.006 0.023 0.0339
Brugia malayi putative neuropeptide receptor 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0116
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0174 0.0473
Echinococcus multilocularis somatostatin receptor 0.002 0.0023 0.0033
Trichomonas vaginalis sugar transport protein, putative 0.0064 0.0254 0.1107
Echinococcus granulosus g protein coupled receptor 0.002 0.0023 0.0033
Echinococcus granulosus peregrin 0.0033 0.0092 0.0136
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0137 0.0633 0.0932
Echinococcus multilocularis neuropeptide receptor 0.002 0.0023 0.0033
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.028 0.0764
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.014 0.0648 0.0977
Echinococcus granulosus solute carrier family 22 0.0064 0.0254 0.0374
Entamoeba histolytica protein kinase, putative 0.014 0.0647 0.1196
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0815 0.3553
Brugia malayi Latrophilin receptor protein 2 0.0099 0.0434 0.1182
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0026 0.0038
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0129 0.0191
Entamoeba histolytica hypothetical protein 0.03 0.1483 0.274
Chlamydia trachomatis histidine--tRNA ligase 0.0015 0 0.0008
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0026 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Schistosoma mansoni hypothetical protein 0.0456 0.2295 0.338
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0043 0.0948
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0038 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Brugia malayi Carboxylesterase family protein 0.0068 0.0276 0.0753
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0023 0.0033
Brugia malayi beta-lactamase family protein 0.0036 0.0106 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Brugia malayi jmjC domain containing protein 0.0098 0.0431 0.1174
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0137 0.0633 0.1168
Chlamydia trachomatis proline--tRNA ligase 0.0048 0.0172 0.3815
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1285 0.5597
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Brugia malayi hypothetical protein 0.002 0.0026 0.007
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1285 0.5597
Schistosoma mansoni chromobox protein 0.0069 0.028 0.0413
Schistosoma mansoni amine GPCR 0.002 0.0023 0.0033
Echinococcus multilocularis neuropeptide receptor A26 0.002 0.0023 0.0033
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0023 0.0033
Brugia malayi Bromodomain containing protein 0.0033 0.0092 0.0251
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0071 0.0192
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0116
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0137 0.0633 1
Leishmania major hypothetical protein, conserved 0.0036 0.0106 0.029
Echinococcus multilocularis acetylcholinesterase 0.0068 0.0276 0.0407
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0023 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.0657 0.2861
Schistosoma mansoni sugar transporter 0.0064 0.0254 0.0374
Onchocerca volvulus 0.002 0.0026 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0023 0.0033
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0137 0.0598
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0254 0.1107
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0106 0.0903
Trichomonas vaginalis sugar transporter, putative 0.0142 0.0657 0.2861
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Giardia lamblia Threonyl-tRNA synthetase 0.0026 0.0054 0.0099
Brugia malayi Sugar transporter family protein 0.0456 0.2295 0.6255
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0023 0.0033
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0023 0.0033
Echinococcus granulosus cpg binding protein 0.0098 0.043 0.0633
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0089 0.0385 0.1677
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Trypanosoma brucei Emopamil binding protein, putative 0.0133 0.0615 0.1675
Echinococcus multilocularis tumor protein p63 0.0394 0.1973 0.2906
Brugia malayi Pre-SET motif family protein 0.0208 0.1004 0.2737
Brugia malayi G-protein coupled receptor 0.002 0.0023 0.0062
Trypanosoma brucei THT1 - hexose transporter, putative 0.0142 0.0657 0.1789
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0064 0.0254 0.2243
Plasmodium falciparum calcium-dependent protein kinase 2 0.014 0.0648 0.0648
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0178 0.0178
Schistosoma mansoni cpg binding protein 0.0098 0.043 0.0633
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2295 0.338
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0023 0.0033
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.0033
Brugia malayi acetyltransferase, GNAT family protein 0.0169 0.0801 0.2182
Echinococcus granulosus Threonyl tRNA synthetase C 0.0026 0.0054 0.0079
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0032
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0712 0.3626 0.9881
Brugia malayi latrophilin 2 splice variant baaae 0.0213 0.103 0.2807
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0023 0.0033
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0043 0.0116
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0152 0.0714 0.1051
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0026 0.0054 0.1193
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0043 0.0076
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0152 0.0714 0.1051
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Brugia malayi Sugar transporter family protein 0.0064 0.0254 0.0692
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0178 0.0178
Plasmodium falciparum threonine--tRNA ligase 0.0026 0.0054 0.0054
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.0157 0.0157
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Schistosoma mansoni glucose transport protein 0.0456 0.2295 0.338
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0023 0.0033
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.1163 0.1713
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Echinococcus granulosus orexin receptor type 2 0.002 0.0023 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0049 0.0133
Loa Loa (eye worm) CXXC zinc finger family protein 0.0093 0.0402 0.1097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Mycobacterium ulcerans beta-lactamase 0.0036 0.0106 0.236
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0023 0.0501
Echinococcus multilocularis General substrate transporter 0.0392 0.1961 0.2888
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0043 0.0948
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1056 0.5414 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0046 0.0067
Toxoplasma gondii sugar transporter ST1 0.0064 0.0254 0.0383
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.0036 0.0106 0.029
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Echinococcus granulosus solute carrier family 22 0.0064 0.0254 0.0374
Echinococcus granulosus hypothetical protein 0.002 0.0023 0.0033
Leishmania major glucose transporter, lmgt1 0.0142 0.0657 0.1789
Loa Loa (eye worm) hypothetical protein 0.0312 0.1544 0.4207
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.014 0.0647 0.0953
Echinococcus multilocularis neuropeptide s receptor 0.002 0.0023 0.0033
Brugia malayi major facilitator superfamily protein 0.0064 0.0254 0.0692
Mycobacterium ulcerans sugar transporter 0.0064 0.0254 0.5643
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0049 0.0072
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0026 0.0054 0.0146
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0038 0.0104
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0137 0.0633 0.0932
Echinococcus granulosus carboxylesterase 5A 0.0068 0.0276 0.0407
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0231 0.0629
Schistosoma mansoni jumonji/arid domain-containing protein 0.0098 0.0431 0.0634
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0023 0.0033
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0023 0.0033
Schistosoma mansoni hypothetical protein 0.0213 0.103 0.1517
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0613 0.0902
Schistosoma mansoni hypothetical protein 0.0099 0.0434 0.0639
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0106 0.1145
Trichomonas vaginalis CAMK family protein kinase 0.014 0.0647 0.2821
Brugia malayi PHD-finger family protein 0.0029 0.0071 0.0192
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0023 0.0062
Mycobacterium tuberculosis Conserved protein 0.0036 0.0106 0.0903
Onchocerca volvulus 0.0058 0.0221 0.1751
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0106 0.0903
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Schistosoma mansoni protein kinase 0.014 0.0647 0.0953
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0179 0.078
Schistosoma mansoni survival motor neuron protein 0.0049 0.0174 0.0256
Onchocerca volvulus Alhambra homolog 0.0029 0.0071 0.0423
Loa Loa (eye worm) hypothetical protein 0.006 0.023 0.0628
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0198 0.0949 0.1397
Schistosoma mansoni jumonji/arid domain-containing protein 0.0098 0.0431 0.0634
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Entamoeba histolytica protein kinase, putative 0.014 0.0647 0.1196
Brugia malayi Dopamine receptor 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0036 0.0106 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0864 0.3763
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0095 0.014
Chlamydia trachomatis lysine--tRNA ligase 0.0102 0.045 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0023 0.0098
Trichomonas vaginalis chromobox protein, putative 0.0069 0.028 0.1221
Echinococcus multilocularis orexin receptor type 2 0.002 0.0023 0.0033
Plasmodium falciparum hexose transporter 0.0456 0.2295 0.2295
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0012 0.026
Echinococcus multilocularis calcium dependent protein kinase 0.0131 0.0602 0.0887
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Schistosoma mansoni chromobox protein 0.0069 0.028 0.0413
Echinococcus multilocularis serotonin receptor 0.002 0.0023 0.0033
Brugia malayi Calcitonin receptor-like protein seb-1 0.0312 0.1544 0.4207
Echinococcus multilocularis dnaJ subfamily B 0.132 0.679 1
Giardia lamblia DNA repair protein RAD52 0.1056 0.5414 1
Brugia malayi Melatonin receptor type 1A 0.002 0.0023 0.0062
Echinococcus granulosus jumonji domain containing protein 0.004 0.0129 0.0191
Loa Loa (eye worm) hypothetical protein 0.0368 0.1836 0.5005
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0262 0.1285 0.3501
Brugia malayi CHD4 protein 0.0017 0.0007 0.0018
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0023 0.0062
Brugia malayi Dopamine receptor protein 2 0.002 0.0023 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Schistosoma mansoni hypothetical protein 0.002 0.0026 0.0038
Plasmodium vivax lysine--tRNA ligase, putative 0.0102 0.045 0.045
Schistosoma mansoni adenoreceptor 0.002 0.0023 0.0033
Brugia malayi hypothetical protein 0.0239 0.1163 0.3169
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0106 0.236
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0023 0.0062
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0049 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Mycobacterium ulcerans hypothetical protein 0.0023 0.0038 0.0848
Schistosoma mansoni histamine h1 receptor 0.002 0.0023 0.0033
Leishmania major protein kinase, putative 0.014 0.0647 0.1764
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0043 0.0079
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0023 0.0061
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0106 0.0463
Schistosoma mansoni sodium/chloride dependent transporter 0.0019 0.0018 0.0027
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.003 0.0076 0.0113
Schistosoma mansoni threonyl-tRNA synthetase 0.0015 0 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0023 0.0033
Trypanosoma brucei THT1 - hexose transporter, putative 0.0142 0.0657 0.1789
Leishmania major hypothetical protein, conserved 0.005 0.0178 0.0486
Schistosoma mansoni cellular tumor antigen P53 0.0058 0.0221 0.0325
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0007 0.0018
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0023 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0088 0.0385
Echinococcus multilocularis serotonin transporter 0.006 0.023 0.0339
Loa Loa (eye worm) histone methyltransferase 0.003 0.0075 0.0204
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.056 0.1526
Onchocerca volvulus 0.0064 0.0254 0.2047
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trypanosoma brucei THT1 - hexose transporter, putative 0.0142 0.0657 0.1789
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.016 0.0751 0.2046
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0038 0.0104
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0023 0.0038 0.0058
Onchocerca volvulus 0.0064 0.0254 0.2047
Leishmania major glucose transporter, lmgt3 0.0142 0.0657 0.1789
Brugia malayi MH2 domain containing protein 0.0123 0.056 0.1526
Schistosoma mansoni opsin-like receptor 0.002 0.0023 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0043 0.0116
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Onchocerca volvulus 0.0064 0.0254 0.2047
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.0157 0.0291
Onchocerca volvulus 0.0064 0.0254 0.2047
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0046 0.0067
Brugia malayi neuropeptide F receptor 0.002 0.0023 0.0062
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0023 0.0033
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.03 0.1483 0.274
Schistosoma mansoni neuropeptide receptor 0.002 0.0023 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1285 0.5597
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0085 0.0128
Brugia malayi AKH receptor 0.002 0.0023 0.0062
Brugia malayi Major Facilitator Superfamily protein 0.0064 0.0254 0.0692
Echinococcus granulosus sex peptide receptor 0.002 0.0023 0.0033
Toxoplasma gondii facilitative glucose transporter GT1 0.0456 0.2295 0.3462
Loa Loa (eye worm) hypothetical protein 0.014 0.0647 0.1764
Brugia malayi Doublecortin family protein 0.002 0.0026 0.007
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Treponema pallidum prolyl-tRNA synthetase 0.0048 0.0172 0.7456
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0815 0.3553
Schistosoma mansoni cpg binding protein 0.0098 0.043 0.0633
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.007
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0026 0.0054 0.0262
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0023 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0456 0.2295 1
Echinococcus granulosus calcium dependent protein kinase 0.0131 0.0602 0.0887
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.016 0.0751 0.2046
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0023 0.0144
Trichomonas vaginalis glucose transporter, putative 0.0142 0.0657 0.2861
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0169 0.0801 0.1179
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0023 0.0033
Schistosoma mansoni glycyl-tRNA synthetase 0.0026 0.0054 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0038 0.0104
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0015 0 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0043 0.0116
Loa Loa (eye worm) hypothetical protein 0.0025 0.0049 0.0133
Brugia malayi beta-lactamase family protein 0.0036 0.0106 0.029
Brugia malayi glycyl-tRNA synthetase 0.0026 0.0054 0.0146
Echinococcus multilocularis solute carrier family 22 0.0064 0.0254 0.0374
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0026 0.0026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0088 0.0385
Schistosoma mansoni amine GPCR 0.002 0.0023 0.0033
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.014 0.0647 0.0953
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0023 0.0033
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0023 0.0033
Brugia malayi Major Facilitator Superfamily protein 0.0064 0.0254 0.0692
Onchocerca volvulus 0.0064 0.0254 0.2047
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0815 0.3553
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0023 0.0033
Echinococcus granulosus phd:f box containing protein 0.0025 0.0049 0.0072
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0023 0.0033
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.016 0.0751 0.2046
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1285 0.5597
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0026 0.0054 0.0079
Mycobacterium ulcerans integral membrane transport protein 0.0064 0.0254 0.5643
Echinococcus multilocularis lysine specific demethylase 5A 0.0093 0.0403 0.0594
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Loa Loa (eye worm) sugar transporter 0.0064 0.0254 0.0692
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0137 0.1015
Loa Loa (eye worm) hypothetical protein 0.0099 0.0434 0.1182
Plasmodium falciparum protein kinase 7 0.1289 0.663 0.663
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0015 0 0.0002
Brugia malayi GnHR receptor homolog 0.002 0.0023 0.0062
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0023 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.0088 0.0385
Toxoplasma gondii transporter, major facilitator family protein 0.0064 0.0254 0.0383
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0023 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0023 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0023 0.0033
Schistosoma mansoni sugar transporter 0.0064 0.0254 0.0374
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Echinococcus granulosus somatostatin receptor 0.002 0.0023 0.0033
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.014 0.0647 0.1764
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0015 0 0.0001
Brugia malayi jmjC domain containing protein 0.0025 0.0049 0.0133
Schistosoma mansoni lysyl-tRNA synthetase 0.0102 0.045 0.0663
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0026 0.0054 0.0146
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0023 0.0033
Echinococcus granulosus Sugar transporter ERD6 protein 0.0064 0.0254 0.0374
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0043 0.0079
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0106 0.0463
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0023 0.0033
Onchocerca volvulus 0.0036 0.0106 0.0739
Trypanosoma brucei glucose transporter, putative 0.0142 0.0657 0.1789
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0023 0.0062
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0071 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0032
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0036 0.0053
Schistosoma mansoni hypothetical protein 0.103 0.5281 0.7778
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0276 0.0407
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0102 0.045 0.6932
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0038 0.0164
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0023 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0043 0.0116
Leishmania major glycyl tRNA synthetase, putative 0.0015 0 0.0001
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0015 0 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0023 0.0062
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0023 0.0033
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0007 0.001
Mycobacterium leprae Probable lipase LipE 0.0036 0.0106 0.1145
Brugia malayi hypothetical protein 0.002 0.0026 0.007
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0262 0.1285 0.3501
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0106 0.0903
Echinococcus granulosus lysine specific demethylase 5A 0.0098 0.0431 0.0634
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0023 0.0038 0.0104
Schistosoma mansoni hypothetical protein 0.002 0.0023 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Leishmania major lysyl-tRNA synthetase, putative 0.0102 0.045 0.1227
Toxoplasma gondii lysine-tRNA ligase 0.0102 0.045 0.0679
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2295 0.338
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0085 0.0125
Echinococcus multilocularis g protein coupled receptor 0.002 0.0023 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.016 0.0751 0.1132
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0254 0.1107
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0049 0.0072
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0032 0.0085 0.0231
Brugia malayi neuropeptide F receptor 0.002 0.0023 0.0062
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Plasmodium falciparum lysine--tRNA ligase 0.0102 0.045 0.045
Echinococcus multilocularis serotonin receptor 0.002 0.0023 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Mycobacterium tuberculosis Conserved protein 0.0036 0.0106 0.0903
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0023 0.0033
Echinococcus granulosus neuropeptide receptor 0.002 0.0023 0.0033
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.014 0.0647 0.0953
Schistosoma mansoni glucose transport protein 0.0456 0.2295 0.338
Loa Loa (eye worm) hypothetical protein 0.0036 0.0106 0.029
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0023 0.0033
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0023 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Brugia malayi larval opioid receptor 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Plasmodium falciparum calcium-dependent protein kinase 5 0.014 0.0648 0.0648
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0049 0.0133
Schistosoma mansoni hypothetical protein 0.0099 0.0434 0.0639
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0049 0.0072
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0106 0.0903
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0046 0.0067
Loa Loa (eye worm) hypothetical protein 0.0039 0.0122 0.0333
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0023 0.0033
Echinococcus multilocularis solute carrier family 22 0.0064 0.0254 0.0374
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.014 0.0648 0.0977
Schistosoma mansoni amine GPCR 0.002 0.0023 0.0033
Trypanosoma cruzi C-8 sterol isomerase, putative 0.072 0.3669 1
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0064 0.0254 0.0374
Echinococcus granulosus fmrfamide receptor 0.002 0.0023 0.0033
Schistosoma mansoni histidyl-tRNA synthetase 0.0015 0 0.0001
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0456 0.2295 0.338
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0169 0.0801 0.1179
Loa Loa (eye worm) hypothetical protein 0.0064 0.0254 0.0692
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0049 0.0074
Chlamydia trachomatis threonine--tRNA ligase 0.0026 0.0054 0.1193
Giardia lamblia PHD finger protein 15 0.0029 0.0071 0.013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0049 0.0133
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Onchocerca volvulus 0.0024 0.0043 0.0177
Onchocerca volvulus 0.0036 0.0106 0.0739
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.0137 0.0633 0.1724
Echinococcus multilocularis carboxylesterase 5A 0.0068 0.0276 0.0407
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0023 0.0061
Giardia lamblia Sugar-proton symporter 0.0064 0.0254 0.0469
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0029 0.0128
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0023 0.0042
Brugia malayi hypothetical protein 0.0064 0.0254 0.0692
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0085 0.0125
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0023 0.0033
Echinococcus multilocularis allatostatin A receptor 0.002 0.0023 0.0033
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0043 0.0948
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0049 0.0133
Brugia malayi G protein-coupled receptor 0.002 0.0023 0.0062
Mycobacterium ulcerans hypothetical protein 0.0036 0.0106 0.236
Schistosoma mansoni myosin xvIII 0.002 0.0023 0.0033
Brugia malayi hypothetical protein 0.002 0.0023 0.0062
Trichomonas vaginalis helicase, putative 0.0021 0.0029 0.0128
Schistosoma mansoni hypothetical protein 0.132 0.679 1
Onchocerca volvulus 0.0093 0.0402 0.336
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0178 0.0486
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0023 0.0062
Trypanosoma cruzi Emopamil binding protein, putative 0.0133 0.0615 0.1675
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0456 0.2295 0.338
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0063 0.0275
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0085 0.0125
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0048 0.0172 0.3815
Loa Loa (eye worm) hypothetical protein 0.0137 0.0633 0.1724
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0071 0.0071
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0106 0.0903
Trypanosoma brucei sugar transporter, putative 0.0064 0.0254 0.0692
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.014 0.0647 0.1764
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0026 0.0038
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0023 0.0033
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2295 0.338
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0026 0.0054 0.2114
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0023 0.0033
Echinococcus granulosus acetylcholinesterase 0.0068 0.0276 0.0407
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.1004 0.2737
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0456 0.2295 0.338
Echinococcus multilocularis neuropeptide receptor 0.002 0.0023 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Leishmania major hypothetical protein, conserved 0.0023 0.0038 0.0104
Trichomonas vaginalis sugar transporter, putative 0.0064 0.0254 0.1107
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0023 0.0033
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0023 0.0062
Echinococcus granulosus GPCR family 2 0.0099 0.0434 0.0639
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.014 0.0648 0.0648
Leishmania major C-8 sterol isomerase-like protein 0.072 0.3669 1
Brugia malayi ORL1-like opioid receptor 0.002 0.0023 0.0062
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0023 0.0033
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0026 0.0054 0.2114
Mycobacterium ulcerans hypothetical protein 0.0024 0.0043 0.0948
Loa Loa (eye worm) hypothetical protein 0.006 0.023 0.0628
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0023 0.0033
Trypanosoma cruzi hexose transporter, putative 0.0142 0.0657 0.1789
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0122 0.0532
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0651 0.1773
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0043 0.0076

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.2 nM Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cells ChEMBL. 18752943

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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