Detailed information for compound 100858

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 274.214 | Formula: C9H15N4O4P
  • H donors: 3 H acceptors: 6 LogP: -2.05 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1CC1)NC(CP(=O)(O)O)Cn1cncn1
  • InChi: 1S/C9H15N4O4P/c14-9(7-1-2-7)12-8(4-18(15,16)17)3-13-6-10-5-11-13/h5-8H,1-4H2,(H,12,14)(H2,15,16,17)
  • InChiKey: KMVIBADRNXEIQC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Cryptococcus neoformans var. neoformans B-3501A Imidazoleglycerol-phosphate dehydratase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans imidazoleglycerol-phosphate dehydratase Get druggable targets OG5_129258 All targets in OG5_129258
Mycobacterium tuberculosis Probable imidazole glycerol-phosphate dehydratase HisB Get druggable targets OG5_129258 All targets in OG5_129258
Mycobacterium leprae Probable imidazole glycerol-phosphate dehydratase HisB Get druggable targets OG5_129258 All targets in OG5_129258
Candida albicans Imidazole glycerol phosphate dehydratase Get druggable targets OG5_129258 All targets in OG5_129258
Candida albicans Imidazole glycerol phosphate dehydratase Get druggable targets OG5_129258 All targets in OG5_129258
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Nanchung homolog Imidazoleglycerol-phosphate dehydratase   202 aa 162 aa 19.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0049 0.0254 0.0255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi glutathione reductase 0.0194 0.1487 0.1491
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0084 0.0551 0.0552
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0102 0.0184
Brugia malayi nuclear hormone receptor 0.0049 0.0254 0.0255
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0076 0.0056
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0022 0.0021 0.0021
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0019 0.0035
Brugia malayi RNA binding protein 0.0452 0.3677 0.3686
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Schistosoma mansoni gabp alpha 0.0073 0.0455 0.0456
Schistosoma mansoni hypothetical protein 0.0222 0.1728 0.1732
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0231 0.0417
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0187 0.1429 0.1429
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Echinococcus granulosus ubiquitin specific peptidase c family 0.0022 0.0021 0.0021
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0192 0.1465 0.1469
Schistosoma mansoni tar DNA-binding protein 0.0452 0.3677 0.3686
Loa Loa (eye worm) beta-lactamase 0.0187 0.1429 0.1432
Echinococcus multilocularis expressed protein 0.0113 0.0799 0.0801
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0124 0.0124
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Brugia malayi hypothetical protein 0.0055 0.0304 0.0305
Schistosoma mansoni phd/f-box containing protein 0.0021 0.0019 0.002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0104 0.072 0.0722
Mycobacterium tuberculosis Probable lipase LipE 0.0187 0.1429 0.1429
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.072 0.0722
Mycobacterium tuberculosis Conserved protein 0.0187 0.1429 0.1429
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0254 0.0255
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0104 0.072 0.0722
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Brugia malayi nuclear receptor RXR 0.0049 0.0254 0.0255
Schistosoma mansoni hypothetical protein 0.0048 0.025 0.025
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0113 0.0799 0.0799
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0217 0.1678 0.1682
Mycobacterium tuberculosis Probable esterase LipL 0.0187 0.1429 0.1429
Schistosoma mansoni smad 0.0042 0.0192 0.0192
Schistosoma mansoni phosphatidylserine receptor 0.0021 0.0019 0.002
Loa Loa (eye worm) PHD-finger family protein 0.0066 0.04 0.0401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi hypothetical protein 0.0028 0.0076 0.0076
Echinococcus multilocularis lysine specific demethylase 5A 0.008 0.0518 0.0519
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0231 0.0417
Schistosoma mansoni nuclear receptor 0.0049 0.0254 0.0255
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0021 0.0002
Giardia lamblia NADH oxidase lateral transfer candidate 0.0067 0.041 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0022 0.0021 0.0021
Mycobacterium tuberculosis Conserved protein 0.0187 0.1429 0.1429
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0223 0.0998
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Echinococcus granulosus cpg binding protein 0.0034 0.0124 0.0124
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.072 0.0722
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0019 0.0035
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0254 0.0255
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0022 0.0039
Schistosoma mansoni hypothetical protein 0.0344 0.2756 0.2764
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Brugia malayi beta-lactamase 0.0187 0.1429 0.1432
Mycobacterium ulcerans hypothetical protein 0.0187 0.1429 0.1432
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0104 0.072 0.0722
Treponema pallidum bacterioferrin (TpF1) 0.0113 0.0799 0.0619
Brugia malayi Nuclear hormone receptor-like 1 0.0104 0.072 0.0722
Echinococcus multilocularis chromobox protein 1 0.0075 0.0477 0.0478
Brugia malayi Fli-1 protein 0.022 0.1709 0.1714
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.0021 0.0523
Entamoeba histolytica Ran family GTPase 0.0024 0.0039 0.0228
Brugia malayi F/Y-rich N-terminus family protein 0.0033 0.0116 0.0116
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0067 0.041 0.0392
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0022 0.0021 0.0021
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0137 0.0998 0.1001
Echinococcus multilocularis tar DNA binding protein 0.0452 0.3677 0.3686
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0254 0.0255
Schistosoma mansoni hypothetical protein 0.0084 0.0551 0.0552
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0194 0.1487 0.1487
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0187 0.1429 0.1432
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0039 0.0039
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0021 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.0443 0.36 0.36
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0151 0.0675
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0049 0.0254 0.0255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0022 0.0021 0.0002
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0022 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0048 0.025 0.025
Onchocerca volvulus Bile acid receptor homolog 0.0104 0.072 0.3152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.1193 0.9974 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0082 0.0534 0.0535
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0192 0.0192
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0021 0.0021
Schistosoma mansoni smad1 5 8 and 0.0042 0.0192 0.0192
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0192 0.0192
Brugia malayi nuclear receptor NHR-88 0.0104 0.072 0.0722
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni ran 0.0024 0.0039 0.0039
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0117 0.0098
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0131 0.0584
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0411 0.333 0.3326
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0272 0.0273
Echinococcus granulosus thyroid hormone receptor alpha 0.0049 0.0254 0.0255
Brugia malayi Bromodomain containing protein 0.0066 0.04 0.0401
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0254 0.0255
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0021 0.0019 0.002
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0304 0.0305
Echinococcus granulosus nuclear receptor nhr 48 0.0049 0.0254 0.0255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi CHE-14 protein 0.005 0.0265 0.0266
Toxoplasma gondii exonuclease III APE 0.0042 0.0194 0.0175
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0049 0.0254 0.0255
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0022 0.0021 0.0002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Echinococcus multilocularis expressed conserved protein 0.011 0.0772 0.0774
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus multilocularis GPCR, family 2 0.0084 0.0551 0.0552
Brugia malayi nuclear receptor RXR 0.0055 0.0304 0.0305
Echinococcus multilocularis expressed protein 0.0034 0.0124 0.0124
Schistosoma mansoni tar DNA-binding protein 0.0452 0.3677 0.3686
Echinococcus multilocularis ecdysone induced protein 78C 0.0104 0.072 0.0722
Brugia malayi photoreceptor-specific nuclear receptor 0.0104 0.072 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Echinococcus granulosus JmjC domain containing protein 4 0.0021 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0089 0.0594 0.0595
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0672 0.5545 1
Schistosoma mansoni ferritin 0.0113 0.0799 0.0801
Brugia malayi Probable ClpP-like protease 0.1193 0.9974 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0443 0.36 0.3052
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0076 0.0056
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0254 0.0255
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0022 0.0021 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.1429 0.2576
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0223 0.0998
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0151 0.0273
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0102 0.0102
Toxoplasma gondii PHD-finger domain-containing protein 0.0066 0.04 0.0382
Trichomonas vaginalis D-aminoacylase, putative 0.0187 0.1429 0.6387
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Schistosoma mansoni hypothetical protein 0.0183 0.1391 0.1395
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0067 0.041 0.0739
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Trichomonas vaginalis rotamase, putative 0.0034 0.0124 0.0555
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0067 0.041 0.0739
Echinococcus granulosus ubiquitin specific protease 41 0.0022 0.0021 0.0021
Schistosoma mansoni smad1 5 8 and 0.0042 0.0192 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0151 0.0675
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0067 0.041 0.0739
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.072 0.0722
Plasmodium falciparum thioredoxin reductase 0.0067 0.041 0.0392
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus multilocularis JmjC domain containing protein 4 0.0021 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0042 0.0196 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Trichomonas vaginalis penicillin-binding protein, putative 0.0187 0.1429 0.6387
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0102 0.0184
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0443 0.36 0.36
Echinococcus granulosus GPCR family 2 0.0084 0.0551 0.0552
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi beta-lactamase family protein 0.0187 0.1429 0.1432
Brugia malayi MH2 domain containing protein 0.0042 0.0192 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0092 0.041
Schistosoma mansoni nuclear receptor nhr-48 0.0049 0.0254 0.0255
Onchocerca volvulus Alhambra homolog 0.0066 0.04 0.1708
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Mycobacterium ulcerans hypothetical protein 0.0354 0.2844 0.2852
Giardia lamblia DUB-1 0.0022 0.0021 0.0523
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0102 0.0083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0124
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0021 0.0002
Brugia malayi ecdysone receptor 0.0049 0.0254 0.0255
Mycobacterium leprae Probable lipase LipE 0.0187 0.1429 0.0686
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis penicillin-binding protein, putative 0.0187 0.1429 0.6387
Onchocerca volvulus 0.0049 0.0254 0.105
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0104 0.072 0.0722
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0782 0.6482 0.6194
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Brugia malayi MH1 domain containing protein 0.0023 0.0034 0.0034
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0021 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0104 0.072 0.0722
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0022 0.0021 0.0021
Leishmania major hypothetical protein, conserved 0.0187 0.1429 0.2576
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0021 0.0096
Brugia malayi nuclear hormone receptor family member nhr-6 0.0049 0.0254 0.0255
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0192 0.0192
Brugia malayi orphan nuclear receptor NR2E1 0.0049 0.0254 0.0255
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0411 0.333 0.2759
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.0021 0.0021
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0022 0.0021 0.0002
Toxoplasma gondii NADPH-glutathione reductase 0.0067 0.041 0.0392
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0051 0.0226
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0104 0.072 0.0722
Echinococcus multilocularis lysine specific demethylase 6a 0.0021 0.0019 0.002
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0131 0.0112
Schistosoma mansoni patched 1 0.005 0.0265 0.0266
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Brugia malayi Heterochromatin protein 1 0.0075 0.0477 0.0478
Schistosoma mansoni nuclear hormone receptor 0.0104 0.072 0.0722
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0113 0.0799 0.0799
Echinococcus granulosus sterol regulatory element binding protein 0.005 0.0265 0.0266
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Brugia malayi MH2 domain containing protein 0.0611 0.5024 0.5037
Loa Loa (eye worm) intermediate filament protein 0.0192 0.1465 0.1469
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0021 0.0021
Trichomonas vaginalis set domain proteins, putative 0.0282 0.2237 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0151 0.0675
Plasmodium falciparum thioredoxin reductase 0.0194 0.1487 0.1474
Schistosoma mansoni intermediate filament proteins 0.0192 0.1465 0.1469
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0104 0.072 0.0722
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0022 0.0021 0.0021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0248 0.1947 0.1952
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0641 0.1155
Schistosoma mansoni hypothetical protein 0.0066 0.04 0.0401
Schistosoma mansoni zinc finger protein 0.0049 0.0254 0.0255
Schistosoma mansoni jumonji/arid domain-containing protein 0.0082 0.0534 0.0535
Schistosoma mansoni RAR-like nuclear receptor 0.0104 0.072 0.0722
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0084 0.0551 0.0552
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0073 0.0327
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Leishmania major hypothetical protein, conserved 0.0021 0.0019 0.0035
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0021 0.0021
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0021 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0272 0.0273
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0112 0.0201
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0076 0.0056
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0024 0.0038 0.0019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0055 0.0304 0.0305
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0272 0.0273
Echinococcus multilocularis Niemann Pick C1 protein 0.0117 0.0833 0.0835
Brugia malayi jmjC domain containing protein 0.0217 0.1678 0.1682
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0018
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0022 0.0002
Mycobacterium tuberculosis Probable imidazole glycerol-phosphate dehydratase HisB 0.0683 0.5641 0.5641
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Onchocerca volvulus Protein ultraspiracle homolog 0.0104 0.072 0.3152
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0194 0.112
Schistosoma mansoni rotamase 0.0034 0.0124 0.0124
Mycobacterium ulcerans esterase/lipase LipP 0.0187 0.1429 0.1432
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0039 0.0039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0272 0.0273
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0104 0.072 0.0722
Onchocerca volvulus 0.0187 0.1429 0.6352
Echinococcus multilocularis smad 0.0042 0.0192 0.0192
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0455 0.0456
Schistosoma mansoni chromobox protein 0.0075 0.0477 0.0478
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0272 0.0273
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0102 0.0083
Echinococcus multilocularis ubiquitin specific protease 41 0.0022 0.0021 0.0021
Brugia malayi Latrophilin receptor protein 2 0.0084 0.0551 0.0552
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0146 0.0146
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0192 0.0192
Schistosoma mansoni jumonji domain containing protein 0.0021 0.0019 0.002
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.025 0.0251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Onchocerca volvulus 0.0192 0.1465 0.6516
Trichomonas vaginalis importin beta-1, putative 0.0026 0.006 0.0267
Onchocerca volvulus 0.0049 0.025 0.1032
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0002 0.0003
Echinococcus granulosus Niemann Pick C1 protein 0.0117 0.0833 0.0835
Echinococcus granulosus phd:f box containing protein 0.0021 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0104 0.072 0.0722
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Schistosoma mansoni ap endonuclease 0.0042 0.0194 0.0194
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Echinococcus multilocularis jumonji domain containing 1A 0.0021 0.0019 0.002
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0231 0.0232
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0782 0.6482 0.6482
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0102 0.0102
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0076 0.0136
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0055 0.0304 0.0305
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0066 0.04 0.0401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Onchocerca volvulus 0.0033 0.0119 0.044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Loa Loa (eye worm) hypothetical protein 0.0036 0.0146 0.0146
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Loa Loa (eye worm) glutathione reductase 0.0194 0.1487 0.1491
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0084 0.0551 0.0552
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi nuclear hormone receptor 0.0104 0.072 0.0722
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni thyroid hormone receptor 0.1133 0.9462 0.9486
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0022 0.0021 0.0021
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0187 0.1429 0.1432
Onchocerca volvulus 0.0282 0.2237 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0492 0.402 0.402
Trichomonas vaginalis ferritin, putative 0.0113 0.0799 0.3573
Echinococcus multilocularis geminin 0.0183 0.1391 0.1395
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0254 0.105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0477 0.0478
Mycobacterium tuberculosis Conserved protein 0.0187 0.1429 0.1429
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Trypanosoma cruzi trypanothione reductase, putative 0.0067 0.041 0.0739
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0104 0.072 0.0722
Loa Loa (eye worm) thioredoxin reductase 0.0194 0.1487 0.1491
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus lysine specific demethylase 6a 0.0021 0.0019 0.002
Echinococcus multilocularis snurportin 1 0.0344 0.2756 0.2764
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0492 0.402 0.402
Toxoplasma gondii hypothetical protein 0.0411 0.333 0.3326
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0104 0.072 0.0722
Echinococcus granulosus ferritin 0.0113 0.0799 0.0801
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0022 0.0022 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0231 0.1035
Brugia malayi tailless protein 0.0049 0.0254 0.0255
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.072 0.0722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Echinococcus granulosus lamin dm0 0.0192 0.1465 0.1469
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0022 0.0021 0.0021
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0018
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus lysine specific demethylase 5A 0.0082 0.0534 0.0535
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0117 0.0212
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0104 0.072 0.0722
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0021 0.0019 0.0035
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0022 0.0021 0.0523
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0112 0.0201
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.01 0.01
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0021 0.0096
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0055 0.0304 0.0305
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi Smad1 0.0042 0.0192 0.0192
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0104 0.072 0.0722
Entamoeba histolytica hypothetical protein 0.0222 0.1728 1
Entamoeba histolytica hypothetical protein 0.0222 0.1728 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Brugia malayi Importin beta-1 subunit 0.0032 0.0112 0.0112
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0272 0.0273
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0192 0.0192
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Echinococcus granulosus importin subunit beta 1 0.0032 0.0112 0.0112
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0022 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0131 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0131 0.0584
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0411 0.333 0.3207
Giardia lamblia PHD finger protein 15 0.0066 0.04 0.9763
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0018
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0194 0.0865
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Brugia malayi chromobox protein homolog 3 0.0042 0.0196 0.0197
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus Smad4 0.0042 0.0192 0.0192
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0022 0.0021 0.0021
Brugia malayi MH2 domain containing protein 0.0042 0.0192 0.0192
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0194 0.0175
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0104 0.072 0.0722
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Toxoplasma gondii PHD-finger domain-containing protein 0.0066 0.04 0.0382
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0076 0.0136
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0067 0.041 0.0411
Plasmodium falciparum glutathione reductase 0.0194 0.1487 0.1474
Mycobacterium tuberculosis Probable reductase 0.0443 0.36 0.36
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0071 0.0317
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0146 0.0146
Mycobacterium tuberculosis Conserved hypothetical protein 0.0354 0.2844 0.2844
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.072 0.0722
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.1029 0.858 0.8602
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0067 0.041 0.0392
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0194 0.0349
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0254 0.0255
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0035 0.0035
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.1193 0.9974 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0049 0.0258 0.0259
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0151 0.0273
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.1193 0.9974 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0019 0.002
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0022 0.0021 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0022 0.0021 0.0021
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0076 0.0056
Loa Loa (eye worm) hypothetical protein 0.0055 0.0304 0.0305
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0672 0.5545 1
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.0021 0.0002
Onchocerca volvulus 0.0049 0.0254 0.105
Schistosoma mansoni importin beta-1 0.0032 0.0112 0.0112
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0443 0.36 0.36
Brugia malayi Intermediate filament tail domain containing protein 0.0192 0.1465 0.1469
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0067 0.041 0.0739
Loa Loa (eye worm) TAR-binding protein 0.0452 0.3677 0.3686
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0151 0.0273
Loa Loa (eye worm) nuclear receptor NHR-67 0.0049 0.0254 0.0255
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0196 0.0789
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0112 0.0112
Brugia malayi beta-lactamase family protein 0.0187 0.1429 0.1432
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0035 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0115 0.0816 0.1472
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0019 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0055 0.0304 0.0305
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0222 0.1728 0.1732
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0021 0.0021
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0102 0.0102
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Schistosoma mansoni ferritin light chain 0.0113 0.0799 0.0801
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Brugia malayi jmjC domain containing protein 0.0021 0.0019 0.002
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0022 0.0021 0.0021
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0344 0.2756 0.2764
Loa Loa (eye worm) hypothetical protein 0.0023 0.0037 0.0037
Brugia malayi jmjC domain containing protein 0.0021 0.0019 0.002
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0782 0.6482 0.6482
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0022 0.0021 0.0021
Echinococcus multilocularis protein dispatched 1 0.0057 0.0325 0.0326
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0022 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0196 0.0877
Trichomonas vaginalis esterase, putative 0.0187 0.1429 0.6387
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0092 0.0623 0.0625
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus geminin 0.0183 0.1391 0.1395
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0104 0.072 0.0722
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0102 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus multilocularis thioredoxin glutathione reductase 0.0194 0.1487 0.1491
Brugia malayi jmjC domain containing protein 0.0082 0.0534 0.0535
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Trichomonas vaginalis ran, putative 0.0024 0.0039 0.0176
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0146 0.0146
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0089 0.0594 0.0595
Loa Loa (eye worm) hypothetical protein 0.0265 0.2091 0.2096
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0022 0.0021 0.0021
Brugia malayi Pre-SET motif family protein 0.0248 0.1947 0.1952
Brugia malayi RNA recognition motif domain containing protein 0.0452 0.3677 0.3686
Echinococcus granulosus lamin 0.0192 0.1465 0.1469
Schistosoma mansoni jumonji/arid domain-containing protein 0.0082 0.0534 0.0535
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Toxoplasma gondii ABC1 family protein 0.0187 0.1429 0.1416
Brugia malayi hypothetical protein 0.0222 0.1728 0.1732
Mycobacterium tuberculosis Probable hydrolase 0.0187 0.1429 0.1429
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi MH1 domain containing protein 0.0042 0.0192 0.0192
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0187 0.1429 0.1432
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0411 0.333 0.3326
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0022 0.0021 0.0021
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0443 0.36 0.36
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0187 0.1429 0.1432
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0022 0.0021 0.0021
Schistosoma mansoni peptidase 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0084 0.0551 0.0552
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0055 0.0304 0.0305
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Plasmodium falciparum phd finger protein, putative 0.0066 0.04 0.0382
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0362 0.0344
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0104 0.072 0.0722
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0102
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0022 0.0021 0.0021
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0146 0.0146
Brugia malayi Calcitonin receptor-like protein seb-1 0.0265 0.2091 0.2096
Echinococcus multilocularis protein patched 0.005 0.0265 0.0266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0194 0.0194
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0021 0.0021
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.1193 0.9974 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0067 0.041 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0124 0.0555
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0231 0.1339
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0024 0.0044
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.0021 0.0021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0022 0.0021 0.0021
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0022 0.0021 0.0021
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0104 0.072 0.0722
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.0184
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0117 0.0833 0.482
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Schistosoma mansoni smad1 5 8 and 0.0042 0.0192 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0102 0.0456
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus jumonji domain containing protein 0.0092 0.062 0.0622
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0022 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Echinococcus multilocularis peregrin 0.0066 0.04 0.0401
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0119 0.0848 0.085
Schistosoma mansoni Smad4 0.0042 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0188 0.1435 0.1439
Brugia malayi jmjC domain containing protein 0.0021 0.0019 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0113 0.0801 0.0803
Echinococcus granulosus expressed protein 0.0034 0.0124 0.0124
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0194 0.0194
Plasmodium vivax importin-beta 2, putative 0.0032 0.0112 0.0092
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0022 0.0021 0.0021
Leishmania major trypanothione reductase 0.0194 0.1487 0.2682
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0231 0.0232
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0131 0.0584
Schistosoma mansoni ferritin 0.0113 0.0799 0.0801
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0102 0.0102
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0022 0.0021 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0102 0.0102
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0102
Plasmodium vivax hypothetical protein, conserved 0.0066 0.04 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.005 0.0224
Schistosoma mansoni cpg binding protein 0.0034 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0022 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0183 0.1391 0.1395
Loa Loa (eye worm) hypothetical protein 0.0181 0.1378 0.1382
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0055 0.0304 0.0305
Schistosoma mansoni hypothetical protein 0.1029 0.858 0.8602
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0067 0.041 0.0411
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0192 0.0192
Toxoplasma gondii ubiquitin-specific protease USP4 0.0022 0.0021 0.0002
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0304 0.0305
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Loa Loa (eye worm) DR-78 0.0049 0.0254 0.0255
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0021 0.0021
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0021 0.0523
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0021 0.0021
Schistosoma mansoni steroid hormone receptor ad4bp 0.0104 0.072 0.0722
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.1029 0.858 0.8602
Schistosoma mansoni jumonji domain containing protein 0.0172 0.13 0.1303
Brugia malayi nuclear hormone receptor family member odr-7 0.0049 0.0254 0.0255
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0117 0.0212
Entamoeba histolytica hypothetical protein 0.0026 0.006 0.0346
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0022 0.0021 0.0021
Brugia malayi intermediate filament protein 0.0192 0.1465 0.1469
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0443 0.36 0.36
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0051 0.0226
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0021 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0187 0.1429 0.2576
Brugia malayi CXXC zinc finger family protein 0.0032 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0002
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0187 0.1429 0.1429
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0039 0.002
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0265 0.1184
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0194 0.0349
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.006 0.0267
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.006 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Echinococcus granulosus snurportin 1 0.0344 0.2756 0.2764
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0113 0.0799 0.0619
Echinococcus multilocularis Niemann Pick C1 protein 0.0167 0.126 0.1263
Trichomonas vaginalis rotamase, putative 0.0033 0.0117 0.0524
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0022 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0051 0.0226
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0021 0.0096
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.006 0.0108
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0067 0.041 0.0739
Loa Loa (eye worm) hypothetical protein 0.0028 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Entamoeba histolytica hypothetical protein 0.0222 0.1728 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0304 0.0305
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0194 0.0194
Echinococcus multilocularis beta LACTamase domain containing family member 0.0187 0.1429 0.1432
Onchocerca volvulus 0.0104 0.072 0.3152
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0117 0.0212
Plasmodium vivax hypothetical protein, conserved 0.0187 0.1429 0.1416
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0254 0.105
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0231 0.0232
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0022 0.0021 0.0021
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Echinococcus granulosus chromobox protein 1 0.0075 0.0477 0.0478
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Schistosoma mansoni apoferritin-2 0.0113 0.0799 0.0801
Loa Loa (eye worm) fli-1 protein 0.022 0.1709 0.1714
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0038 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0477 0.2131
Schistosoma mansoni nuclear receptor 0.0049 0.0254 0.0255
Schistosoma mansoni ets-related 0.022 0.1709 0.1714
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0231 0.0417
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0194 0.4725
Loa Loa (eye worm) nuclear hormone receptor 0.0049 0.0254 0.0255
Loa Loa (eye worm) Smad1 0.0042 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0022 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0222 0.1728 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0104 0.072 0.0722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) MH2 domain-containing protein 0.0611 0.5024 0.5037
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Plasmodium falciparum importin beta, putative 0.0032 0.0112 0.0092
Echinococcus multilocularis thyroid hormone receptor alpha 0.1133 0.9462 0.9486
Schistosoma mansoni cpg binding protein 0.0034 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni retinoic acid receptor RXR 0.0104 0.072 0.0722
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Echinococcus granulosus jumonji domain containing 1A 0.0021 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Schistosoma mansoni ferritin 0.0113 0.0799 0.0801
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0022 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0131 0.0584
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0022 0.0021 0.0021
Toxoplasma gondii thioredoxin reductase 0.0194 0.1487 0.1474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni ferritin light chain 0.0113 0.0799 0.0801
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0117 0.0212
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0084 0.0551 0.0552
Echinococcus granulosus FTZ F1 alpha 0.0104 0.072 0.0722
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0067 0.041 0.0392
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0039 0.0961
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0124 0.0124
Echinococcus granulosus smad 0.0042 0.0192 0.0192
Schistosoma mansoni hypothetical protein 0.0084 0.0551 0.0552
Brugia malayi AF-10 protein 0.0022 0.0022 0.0022
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0492 0.402 0.351
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi nuclear receptor NHR-88 0.0049 0.0254 0.0255
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0034 0.0034
Brugia malayi Ets-domain containing protein 0.0073 0.0455 0.0456
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0187 0.1429 0.1429
Brugia malayi hypothetical protein 0.0055 0.0304 0.0305
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0231 0.1339
Echinococcus granulosus Protein patched homolog 1 0.005 0.0265 0.0266
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Brugia malayi hypothetical protein 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0092 0.0623 0.0625
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0039 0.002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Brugia malayi hypothetical protein 0.0049 0.0254 0.0255
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0022 0.0021 0.0021
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0187 0.1429 0.1432
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Schistosoma mansoni tar DNA-binding protein 0.0452 0.3677 0.3686
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0254 0.0255
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0022 0.0021 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0104 0.072 0.0722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0004 0.0018
Brugia malayi PHD-finger family protein 0.0023 0.0037 0.0037
Mycobacterium ulcerans bacterioferritin BfrB 0.0113 0.0799 0.0801
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0102
Loa Loa (eye worm) steroid hormone receptor 0.0104 0.072 0.0722
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0129 0.0129
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0022 0.0021 0.0021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0265 0.2091 0.2096
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.0184
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0104 0.072 0.0722
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0019 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0231 0.0417
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0021 0.0021
Brugia malayi RNA, U transporter 1 0.0092 0.0616 0.0617
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0151 0.0675
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0055 0.0304 0.0305
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0067 0.041 0.041
Brugia malayi conserved hypotetical protein 0.0049 0.0254 0.0255
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0104 0.072 0.0722
Loa Loa (eye worm) hypothetical protein 0.0062 0.0361 0.0362
Loa Loa (eye worm) hypothetical protein 0.0187 0.1429 0.1432
Echinococcus granulosus Niemann Pick C1 protein 0.0167 0.126 0.1263
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0049 0.0254 0.0255
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0102 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0104 0.072 0.0722
Loa Loa (eye worm) RNA binding protein 0.0452 0.3677 0.3686
Echinococcus multilocularis PHD finger protein rhinoceros 0.0066 0.04 0.0401
Echinococcus multilocularis phd:f box containing protein 0.0021 0.0019 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0073 0.0327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.005 0.0224
Loa Loa (eye worm) transcription factor SMAD2 0.0611 0.5024 0.5037
Echinococcus multilocularis lamin 0.0192 0.1465 0.1469
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Echinococcus multilocularis jumonji domain containing protein 0.0092 0.062 0.0622
Plasmodium vivax ubiquitin specific protease, putative 0.0022 0.0021 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0104 0.072 0.0722
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0103 0.071 0.0712
Brugia malayi MH1 domain containing protein 0.0023 0.0034 0.0034
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0062 0.0365 0.0366
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0452 0.3677 0.3686
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus multilocularis Smad4 0.0042 0.0192 0.0192
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0066 0.04 0.0401
Echinococcus granulosus peregrin 0.0066 0.04 0.0401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Echinococcus granulosus PHD finger protein rhinoceros 0.0066 0.04 0.0401
Onchocerca volvulus 0.0032 0.0109 0.0394
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0022 0.0021 0.0021
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0217 0.1678 0.1682
Loa Loa (eye worm) nuclear factor I 0.0023 0.0034 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Echinococcus multilocularis lamin dm0 0.0192 0.1465 0.1469
Echinococcus multilocularis chromobox protein 1 0.0075 0.0477 0.0478
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.0021 0.0124
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0022 0.0021 0.0021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Leishmania major GTP-binding protein, putative 0.0024 0.0039 0.0071
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0117 0.0679
Brugia malayi nuclear receptor NHR-67 0.0049 0.0254 0.0255
Trichomonas vaginalis D-aminoacylase, putative 0.0187 0.1429 0.6387
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Loa Loa (eye worm) hypothetical protein 0.0187 0.1429 0.1432
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0022 0.0021 0.0002
Loa Loa (eye worm) hypothetical protein 0.0187 0.1429 0.1432
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0672 0.5545 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0146 0.0146
Brugia malayi Ets-domain containing protein 0.0073 0.0455 0.0456
Brugia malayi Pre-SET motif family protein 0.0036 0.0146 0.0146
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0304 0.0305
Schistosoma mansoni lamin 0.0192 0.1465 0.1469
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Brugia malayi Niemann-Pick C1 protein precursor 0.0117 0.0833 0.0835
Brugia malayi Steroid receptor seven-up type 2 0.0104 0.072 0.0722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni apoferritin-2 0.0113 0.0799 0.0801
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Mycobacterium ulcerans bacterioferritin BfrA 0.0113 0.0799 0.0801
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0022 0.0021 0.0002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Plasmodium falciparum ubiquitin specific protease, putative 0.0022 0.0021 0.0002
Schistosoma mansoni peptidase Clp (S14 family) 0.1193 0.9974 1
Echinococcus granulosus expressed conserved protein 0.011 0.0772 0.0774
Brugia malayi ubiquitin specific protease 14 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi isocitrate dehydrogenase 0.0031 0.0102 0.0102
Loa Loa (eye worm) latrophilin receptor protein 2 0.0084 0.0551 0.0552
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0318 0.2539 0.4579
Schistosoma mansoni hypothetical protein 0.0181 0.1378 0.1382
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0194 0.0194
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0194 0.0865
Schistosoma mansoni tar DNA-binding protein 0.0452 0.3677 0.3686
Giardia lamblia Hypothetical protein 0.0022 0.0021 0.0523
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0022 0.0021 0.0021
Echinococcus granulosus peptidase Clp S14 family 0.0782 0.6482 0.6499
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0104 0.072 0.0722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0104 0.072 0.0722
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0067 0.041 0.0411
Trichomonas vaginalis ubiquitin specific protease, putative 0.0022 0.0021 0.0096
Mycobacterium leprae conserved hypothetical protein 0.0187 0.1429 0.0686
Trichomonas vaginalis glutathione reductase, putative 0.0067 0.041 0.1831
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0222 0.1728 0.1732
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0022 0.0021 0.0021
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni transcription factor LCR-F1 0.0222 0.1728 0.1732
Brugia malayi hypothetical protein 0.0049 0.0254 0.0255
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Plasmodium vivax SET domain protein, putative 0.0036 0.0146 0.0127
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0022 0.0021 0.0021
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0094 0.0641 0.1155
Brugia malayi steroid hormone receptor 0.0104 0.072 0.0722
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0104 0.072 0.3152
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Echinococcus granulosus intermediate filament protein 0.0192 0.1465 0.1469
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0194 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.005 0.0224
Brugia malayi Thioredoxin reductase 0.0194 0.1487 0.1491
Mycobacterium tuberculosis Probable oxidoreductase 0.0492 0.402 0.402
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0067 0.041 0.0411
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0254 0.0255
Loa Loa (eye worm) hypothetical protein 0.0187 0.1429 0.1432
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0194 0.0349
Onchocerca volvulus 0.0187 0.1429 0.6352
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0004 0.0018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0039 0.002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0084 0.0551 0.0552
Echinococcus granulosus beta LACTamase domain containing family member 0.0187 0.1429 0.1432
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0018
Plasmodium vivax glutathione reductase, putative 0.0194 0.1487 0.1474
Schistosoma mansoni thyroid hormone receptor 0.1133 0.9462 0.9486
Loa Loa (eye worm) hypothetical protein 0.0104 0.072 0.0722
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.1193 0.9974 1
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0022 0.0021 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0452 0.3677 0.3686
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0192 0.0192
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0022 0.0021 0.0021
Trypanosoma brucei trypanothione reductase 0.0194 0.1487 0.2682
Brugia malayi cytoplasmic intermediate filament protein 0.0103 0.071 0.0712
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0021 0.0021
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0455 0.0456
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0067 0.041 0.0411
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0104 0.072 0.0722
Mycobacterium leprae Probable imidazole glycerol-phosphate dehydratase HisB 0.0337 0.27 0.2071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0272 0.0273
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0067 0.041 0.0392
Echinococcus granulosus tar DNA binding protein 0.0452 0.3677 0.3686
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0092 0.041
Leishmania major hypothetical protein, conserved 0.0028 0.0076 0.0136
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0272 0.0273
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0641 0.1155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0071 0.0317
Toxoplasma gondii hypothetical protein 0.0108 0.0759 0.0743
Onchocerca volvulus 0.0187 0.1429 0.6352
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Echinococcus granulosus thioredoxin glutathione reductase 0.0194 0.1487 0.1491
Loa Loa (eye worm) hypothetical protein 0.0192 0.1465 0.1469
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus multilocularis ferritin 0.0113 0.0799 0.0801
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0254 0.0255
Echinococcus multilocularis nuclear receptor nhr 48 0.0049 0.0254 0.0255
Leishmania major mitochondrial DNA polymerase beta 0.0672 0.5545 1
Schistosoma mansoni chromobox protein 0.0075 0.0477 0.0478
Brugia malayi TAR-binding protein 0.0452 0.3677 0.3686
Brugia malayi PHD-finger family protein 0.0066 0.04 0.0401
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0022 0.0021 0.0096
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0039 0.0071
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0067 0.041 0.0411
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0223 0.0911
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0231 0.0232
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0076 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0196 0.0877
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0022 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni ferritin 0.0113 0.0799 0.0801
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0146 0.0146
Brugia malayi ecdysteroid receptor 0.0104 0.072 0.0722
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Trichomonas vaginalis mercuric reductase, putative 0.0067 0.041 0.1831
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0151 0.0675
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.0021 0.0021
Toxoplasma gondii hypothetical protein 0.0022 0.0021 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.041 0.0739
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0455 0.0456
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0104 0.072 0.0722
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0094 0.0641 0.1155
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0067 0.041 0.0411
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0067 0.041 0.0739
Schistosoma mansoni hypothetical protein 0.0048 0.025 0.025
Mycobacterium tuberculosis Probable lipase LipD 0.0187 0.1429 0.1429
Echinococcus multilocularis peptidase Clp (S14 family) 0.0782 0.6482 0.6499
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0049 0.0254 0.0255
Plasmodium vivax thioredoxin reductase, putative 0.0194 0.1487 0.1474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Echinococcus multilocularis cpg binding protein 0.0034 0.0124 0.0124
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0022 0.0021 0.0021
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0146 0.0127
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0084 0.0551 0.0552
Onchocerca volvulus 0.0192 0.1465 0.6516
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi jmjC domain containing protein 0.0021 0.0019 0.002
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0022 0.0021 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0104 0.072 0.0722
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0022 0.0021 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0093 0.0418
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.005 0.0265 0.0266
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0131 0.0584
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0272 0.0273
Echinococcus granulosus chromobox protein 1 0.0075 0.0477 0.0478
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0067 0.041 0.0392
Echinococcus granulosus ecdysone induced protein 78C 0.0104 0.072 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Mycobacterium ulcerans imidazoleglycerol-phosphate dehydratase 0.0683 0.5641 0.5655
Schistosoma mansoni ran 0.0024 0.0039 0.0039
Echinococcus multilocularis expressed protein 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.005 0.0265 0.0266
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0022 0.0021 0.0039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0104 0.072 0.0722
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0131 0.0584
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0022
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0022 0.0021 0.0021
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0049 0.0254 0.0255
Schistosoma mansoni protein phosphatase 2C 0.0021 0.0019 0.002
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0477 0.2131
Echinococcus granulosus expressed protein 0.0113 0.0799 0.0801
Loa Loa (eye worm) hypothetical protein 0.0187 0.1429 0.1432
Plasmodium falciparum glutathione reductase 0.0067 0.041 0.0392
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0049 0.0254 0.0255
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0022 0.0039
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0022 0.0021 0.0021
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0039 0.0071
Schistosoma mansoni hypothetical protein 0.0048 0.025 0.025
Giardia lamblia GTOR 0.0046 0.0231 0.565
Schistosoma mansoni ap endonuclease 0.0042 0.0194 0.0194
Schistosoma mansoni cpg binding protein 0.0032 0.0109 0.0109
Echinococcus multilocularis FTZ F1 alpha 0.0104 0.072 0.0722
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0104 0.072 0.0722
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0021 0.0523
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0119
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0187 0.1429 0.1432
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0109 0.0109
Brugia malayi MH1 domain containing protein 0.0042 0.0192 0.0192
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0231 0.0417
Brugia malayi latrophilin 2 splice variant baaae 0.0181 0.1378 0.1382
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0104 0.072 0.0722
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0194 0.0175
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0039 0.0071
Echinococcus multilocularis musashi 0.0192 0.1465 0.1469
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0084 0.0551 0.0552
Loa Loa (eye worm) hypothetical protein 0.0032 0.0112 0.0112
Mycobacterium ulcerans beta-lactamase 0.0187 0.1429 0.1432
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0265 0.2091 0.2096
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0022 0.0021 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trypanosoma cruzi trypanothione reductase, putative 0.0194 0.1487 0.2682
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0104 0.072 0.0722
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0112 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0423 0.0424
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0104 0.072 0.0722
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0067 0.041 0.0739
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0318 0.2539 0.4579
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0022 0.0021 0.0124
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0318 0.2539 0.4579
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0022 0.0021 0.0021
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0842 0.6993 0.7011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0021
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0117 0.0833 0.0835
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0067 0.041 0.0221
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Schistosoma mansoni lamin 0.0192 0.1465 0.1469
Schistosoma mansoni coup transcription factor 0.0104 0.072 0.0722
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0092 0.0623 0.0625
Leishmania major importin beta-1 subunit, putative 0.0026 0.006 0.0108
Echinococcus multilocularis sterol regulatory element binding protein 0.005 0.0265 0.0266
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0254 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0174 0.0778
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0022 0.0021 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0021 0.0096
Trichomonas vaginalis D-aminoacylase, putative 0.0187 0.1429 0.6387
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0231 0.1035
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0067 0.041 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0073 0.0327
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0194 0.0349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0231 0.1035
Mycobacterium ulcerans lipase LipD 0.0187 0.1429 0.1432
Treponema pallidum NADH oxidase 0.0067 0.041 0.0221
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0049 0.0258 0.0259
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0004 0.0018
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.1193 0.9974 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0104 0.072 0.0722
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0022 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0049 0.0254 0.0255
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0231 0.0232
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0022 0.0021 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0051 0.0226
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0022 0.0021 0.0002
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0022 0.0021 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0194 0.0194
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0022 0.0021 0.0039
Entamoeba histolytica hypothetical protein 0.0022 0.0021 0.0124
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0231 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.1429 0.2576

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 17 uM Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans ChEMBL. 10450980
IC50 (binding) = 17 uM Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans ChEMBL. 10450980
Ki (binding) = 4 uM Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans ChEMBL. 10450980
Ki (binding) = 4 uM Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans ChEMBL. 10450980
Kis (binding) = 19 uM Kinetic constant for the inhibition of imidazole glycerol phosphate dehydratase (IGPD) ChEMBL. 10450980
Kis (binding) = 19 uM Kinetic constant for the inhibition of imidazole glycerol phosphate dehydratase (IGPD) ChEMBL. 10450980

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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