Detailed information for compound 1065617

Basic information

Technical information
  • TDR Targets ID: 1065617
  • Name: N-ethyl-N-[[3-(4-methoxyphenyl)-1,2,4-oxadiaz ol-5-yl]methyl]-2-methylfuran-3-carboxamide
  • MW: 341.361 | Formula: C18H19N3O4
  • H donors: 0 H acceptors: 3 LogP: 2.59 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(C(=O)c1ccoc1C)Cc1onc(n1)c1ccc(cc1)OC
  • InChi: 1S/C18H19N3O4/c1-4-21(18(22)15-9-10-24-12(15)2)11-16-19-17(20-25-16)13-5-7-14(23-3)8-6-13/h5-10H,4,11H2,1-3H3
  • InChiKey: YLPMPKLHEIKSSG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-ethyl-N-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]-2-methyl-furan-3-carboxamide
  • N-ethyl-N-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]-2-methyl-3-furancarboxamide
  • N-ethyl-N-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]-2-methyl-3-furamide
  • ZINC04943553
  • BAS 13319531
  • STK322152

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0043 0.0054
Brugia malayi steroid hormone receptor 0.0023 0.0056 0.007
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0223 0.1275 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0078 0.0082
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0507 0.0631
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0077 0.0387 1
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.03 0.0359
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0164 0.019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0098 0.0107
Schistosoma mansoni zinc finger protein 0.0026 0.0074 0.0066
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0071 0.0062
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0507 0.0618
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.014 0.0159
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0013
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0036
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0024
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.0033
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.014 0.322
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0625 0.3722 0.4631
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0019 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0011 0.0003
Onchocerca volvulus 0.0074 0.0369 0.1868
Plasmodium falciparum glutathione reductase 0.0049 0.0218 0.0554
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0663 0.0825
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0077 0.0389 0.0591
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0102 0.0242
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0022 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Loa Loa (eye worm) ctsf protein 0.0016 0.0019 0.0024
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0206 0.0242
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0625 0.3722 0.4631
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0181 0.0863
Brugia malayi glutaminase DH11.1 0.028 0.1622 0.2019
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.2365 0.2932
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0177 0.0998 0.1229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0036 0.0135 0.0113
Echinococcus granulosus transcription factor btf3 0.0036 0.0137 0.0156
Echinococcus multilocularis peregrin 0.0036 0.0138 0.0157
Schistosoma mansoni microtubule-associated protein tau 0.0707 0.4219 0.441
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0206 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0056 0.007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.033 0.0411
Brugia malayi Pre-SET motif family protein 0.0031 0.0109 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0056 0.007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0509 0.0522
Schistosoma mansoni cpg binding protein 0.0028 0.0091 0.0083
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0297 0.0356
Brugia malayi phosphofructokinase 0.0111 0.0596 0.0742
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.021 0.1196 0.1241
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0027 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0162 0.0154
Trichomonas vaginalis glutaminase, putative 0.028 0.1622 0.1616
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0067 0.0083
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0231 0.1326 0.7592
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0223 0.1275 0.1255
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.1656 1 1
Mycobacterium ulcerans integral membrane transporter 0.0036 0.0135 0.0113
Onchocerca volvulus 0.0026 0.0078 0.0314
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0056 0.007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0146 0.0167
Loa Loa (eye worm) cysteine protease 0.0016 0.0019 0.0024
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.033 0.0334
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0071 0.0049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0021
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.021 0.1196 0.1241
Leishmania major trypanothione reductase 0.0049 0.0218 0.0216
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0231 0.1326 0.132
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0297 0.0356
Echinococcus multilocularis transcription factor btf3 0.0036 0.0137 0.0156
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0064 0.0337
Echinococcus multilocularis GPCR, family 2 0.0047 0.0206 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0056 0.007
Giardia lamblia PHD finger protein 15 0.003 0.01 0.0455
Echinococcus multilocularis chromobox protein 1 0.0071 0.0353 0.0425
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0078 0.0097
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0199 0.0192
Brugia malayi chromobox protein homolog 3 0.004 0.0162 0.0202
Toxoplasma gondii thioredoxin reductase 0.0049 0.0218 0.0554
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0109 0.0102
Onchocerca volvulus 0.0324 0.1892 1
Echinococcus multilocularis carbonic anhydrase 0.0625 0.3722 0.4623
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0258 0.1489 0.2314
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0218 0.0257
Mycobacterium ulcerans transferase 0.0074 0.0369 0.0347
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0596 0.0728
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.014 0.0134
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0078 0.0097
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.0437 0.0446
Echinococcus granulosus chromobox protein 1 0.0071 0.0353 0.0425
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0081 0.0414 0.0501
Loa Loa (eye worm) hypothetical protein 0.004 0.0162 0.0202
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0837 0.1028
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0019 0.0024
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.1219 0.1517
Plasmodium vivax sulfate transporter, putative 0.0036 0.0135 0.0938
Echinococcus granulosus hormone sensitive lipase 0.021 0.1196 0.1475
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.06 0.0922
Schistosoma mansoni rab6-interacting 0.004 0.0164 0.016
Schistosoma mansoni lipoxygenase 0.0105 0.0555 0.057
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0507 0.05
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0056 0.007
Schistosoma mansoni hormone-sensitive lipase (S09 family) 0.021 0.1196 0.1241
Onchocerca volvulus 0.004 0.0164 0.0777
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0056 0.007
Toxoplasma gondii cathepsin CPL 0.0016 0.0019 0.0019
Plasmodium falciparum phd finger protein, putative 0.003 0.01 0.0239
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0013
Loa Loa (eye worm) hypothetical protein 0.004 0.0161 0.0201
Onchocerca volvulus 0.0085 0.0437 0.2231
Schistosoma mansoni hypothetical protein 0.0016 0.0015 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0507 0.05
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0297 0.0299
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0043 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0083
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0022 0.0013
Schistosoma mansoni hypothetical protein 0.0081 0.0414 0.0422
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0056 0.0046
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0004 0.0005
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0137 0.0949
Loa Loa (eye worm) doublecortin family protein 0.004 0.0164 0.0205
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.014 0.0127
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0206 0.0256
Entamoeba histolytica hypothetical protein 0.004 0.0164 0.0153
Trypanosoma cruzi ISWI complex protein 0.0016 0.0015 0.0004
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0677 0.0645
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0071 0.0074
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0218 0.0271
Loa Loa (eye worm) carbonic anhydrase 3 0.1334 0.8037 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0056 0.0055
Brugia malayi Bromodomain containing protein 0.0083 0.0425 0.0528
Echinococcus multilocularis zinc finger protein 0.0026 0.0074 0.0078
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0223 0.1275 0.1574
Brugia malayi hypothetical protein 0.004 0.0164 0.0205
Schistosoma mansoni hypothetical protein 0.004 0.0164 0.016
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0024
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0297 0.0447
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.029 0.0292
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0019 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0056 0.0046
Brugia malayi Pre-SET motif family protein 0.0214 0.1219 0.1517
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0067 0.0044
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0625 0.3722 0.4631
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0067 0.0044
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0507 0.0617
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0596 0.0589
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0596 0.0613
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0043 0.0021
Echinococcus granulosus dynactin 5 p25 0.0077 0.0387 0.0467
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.0514 0.0626
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0187 0.0218
Wolbachia endosymbiont of Brugia malayi carbonic anhydrase 0.0044 0.0187 0.4524
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.174 0.1805
Mycobacterium tuberculosis Probable serine acetyltransferase CysE (sat) 0.0077 0.0387 0.0587
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0028 0.0017
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0842 0.5044 0.6271
Echinococcus granulosus zinc finger protein 0.0026 0.0074 0.0078
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0056 0.0055
Mycobacterium ulcerans hypothetical protein 0.0044 0.0187 0.0165
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0036
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0164 0.1161
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0187 0.0218
Wolbachia endosymbiont of Brugia malayi 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 0.0077 0.0387 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0206 0.0242
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0022 0.0028
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0826 0.1028
Schistosoma mansoni hypothetical protein 0.004 0.0164 0.016
Plasmodium vivax vivapain-2 0.0016 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0149 0.0826 0.1028
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0071 0.0074
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0074 0.0368 0.0444
Brugia malayi DnaJ domain containing protein 0.0063 0.03 0.0374
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0231 0.1326 0.3543
Brugia malayi MH2 domain containing protein 0.0122 0.0663 0.0825
Echinococcus multilocularis lamin dm0 0.0026 0.0078 0.0082
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0056 0.007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0094
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1334 0.8037 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.01 0.0111
Echinococcus granulosus RUN 0.004 0.0164 0.019
Echinococcus multilocularis dnaJ subfamily C 6 0.0063 0.03 0.036
Mycobacterium ulcerans carbonic anhydrase 0.1583 0.9553 0.9552
Schistosoma mansoni apoptosis regulator bax 0.0081 0.0414 0.0422
Brugia malayi SET domain containing protein 0.0013 0 0.0001
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0024
Brugia malayi 6-phosphofructokinase 0.0111 0.0596 0.0742
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0826 0.1028
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0596 0.0728
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0837 0.0865
Trypanosoma brucei carbonic anhydrase-like protein 0.1334 0.8037 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Echinococcus multilocularis musashi 0.0026 0.0078 0.0082
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0507 0.0631
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0022 0.0016
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.014 0.0118
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0161 0.02
Schistosoma mansoni chromobox protein 0.0071 0.0353 0.0358
Loa Loa (eye worm) hypothetical protein 0.0049 0.0216 0.0269
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0019 0.0009
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0596 0.0575
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0223 0.1275 0.1586
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0043 0.0039
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0297 0.0275
Echinococcus granulosus peregrin 0.0036 0.0138 0.0157
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0056 0.0055
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.033 0.0333
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0625 0.3722 0.4631
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0056 0.007
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0022 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0216 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Onchocerca volvulus 0.0243 0.1399 0.7364
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0161 0.0185
Trypanosoma brucei ISWI complex protein 0.0016 0.0015 0.0004
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0053 0.0065
Loa Loa (eye worm) hypothetical protein 0.005 0.022 0.0274
Brugia malayi intermediate filament protein 0.0026 0.0078 0.0097
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.014 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0162 0.0154
Brugia malayi follicle stimulating hormone receptor 0.0256 0.1475 0.1835
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0137 0.0129
Schistosoma mansoni lamin 0.0026 0.0078 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.018 0.0176
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0071 0.0049
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0164 0.019
Brugia malayi hypothetical protein 0.004 0.0164 0.0205
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0596 0.0728
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0677 0.1042
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0102 0.0634
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0067 0.005
Schistosoma mansoni carbonic anhydrase-related 0.0625 0.3722 0.3888
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0067 0.0044
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0056 0.0046
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0071 0.0074
Entamoeba histolytica hypothetical protein 0.004 0.0164 0.0153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Entamoeba histolytica ankyrin, putative 0.0077 0.0387 0.0386
Echinococcus multilocularis geminin 0.034 0.1989 0.2464
Leishmania major hypothetical protein, conserved 0.0218 0.1244 0.1292
Entamoeba histolytica carbonic anhydrase, putative 0.1583 0.9553 1
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0596 0.0605
Echinococcus multilocularis cysteine protease 0.0016 0.0019 0.0009
Loa Loa (eye worm) fibroinase 0.0016 0.0019 0.0024
Schistosoma mansoni carbonic anhydrase 0.1583 0.9553 1
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0056 0.007
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0164 0.019
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0029 0.0046
Loa Loa (eye worm) hypothetical protein 0.0081 0.0414 0.0515
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0036 0.0135 0.0332
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0043 0.0036
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0019 0.0009
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0596 0.0916
Echinococcus granulosus cpg binding protein 0.0032 0.0112 0.0125
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.033 0.0397
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.033 0.0397
Onchocerca volvulus Putative sulfate transporter 0.0223 0.1278 0.6719
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0022 0.0013
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.033 0.0397
Echinococcus multilocularis carbonic anhydrase 0.0625 0.3722 0.4623
Mycobacterium ulcerans hypothetical protein 0.0025 0.0071 0.0049
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0022 0.0013
Toxoplasma gondii inorganic anion transporter, sulfate permease (SulP) family protein 0.0036 0.0135 0.0332
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0596 0.0612
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0094
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0507 0.05
Onchocerca volvulus 0.0023 0.0056 0.0198
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0018
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0019 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.06 0.0922
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0596 0.0613
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0018
Brugia malayi Thioredoxin reductase 0.0049 0.0218 0.0271
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0056 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0294 0.0366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0013
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0102 0.0242
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0056 0.0046
Brugia malayi Inositol-1 0.0036 0.014 0.0174
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.06 0.0922
Entamoeba histolytica hypothetical protein 0.0036 0.0137 0.0123
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0164 0.019
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0663 0.0825
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0022 0.0014
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0223 0.1275 0.729
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0012 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0019 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0056 0.007
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0267 0.0318
Brugia malayi Heterochromatin protein 1 0.0071 0.0353 0.0439
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0353 0.0345
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0297 0.0299
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0043 0.0123
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.021 0.0202
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0067 0.0086
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0826 0.1028
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0164 0.0411
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.06 0.0565
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0328 0.0394
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0146 0.0167
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0043 0.0123
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0081 0.0414 0.0422
Echinococcus granulosus lamin dm0 0.0026 0.0078 0.0082
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0022 0.0013
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0067 0.0057
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0219 0.0258
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0019 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0094
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0223 0.1275 0.1324
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0164 0.016
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0223 0.1275 0.1574
Brugia malayi hypothetical protein 0.0017 0.0022 0.0027
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0808 0.0788
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0223 0.1275 0.1574
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0507 0.05
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0043 0.0579
Loa Loa (eye worm) hypothetical protein 0.0102 0.0539 0.0671
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0231 0.1326 0.3543
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0064 0.0082
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1334 0.8037 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0029 0.0131
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0509 0.062
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0157 0.0181
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0056 0.0046
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.174 1
Schistosoma mansoni hypothetical protein 0.0081 0.0414 0.0422
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0157 0.0181
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0056 0.0055
Schistosoma mansoni hypothetical protein 0.003 0.01 0.0093
Schistosoma mansoni lamin 0.0026 0.0078 0.0069
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0102 0.0683
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0071 0.0093
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0071 0.0074
Onchocerca volvulus Alhambra homolog 0.003 0.01 0.0435
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.014 0.0132
Entamoeba histolytica hypothetical protein 0.004 0.0164 0.0153
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0071 0.0074
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0797 0.0978
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0297 0.0299
Brugia malayi jmjC domain containing protein 0.004 0.0161 0.02
Echinococcus granulosus carbonic anhydrase 0.0625 0.3722 0.4623
Loa Loa (eye worm) hypothetical protein 0.0031 0.011 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0078 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0596 0.0589
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0011 0.0003
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0137 0.0155
Leishmania major cathepsin L-like protease 0.0063 0.03 0.0302
Brugia malayi CHD4 protein 0.0015 0.0012 0.0015
Echinococcus multilocularis carbonic anhydrase 0.0625 0.3722 0.4623
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0056 0.0055
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0056 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.1244 0.1536
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.0007
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0137 0.0336
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0022 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0056 0.007
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0056 0.007
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0677 0.1042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.033 0.0397
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0102 0.0094
Leishmania major cathepsin L-like protease 0.0063 0.03 0.0302
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0027 0.0016
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.0085
Echinococcus granulosus microtubule associated protein 2 0.0707 0.4219 0.5243
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.1475 0.1835
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0596 0.056
Brugia malayi Bromodomain containing protein 0.0043 0.0183 0.0228
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0056 0.007
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0199 0.1426
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0049 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.01 0.0239
Echinococcus granulosus geminin 0.034 0.1989 0.2464
Echinococcus granulosus GPCR family 2 0.0047 0.0206 0.0242
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0039
Schistosoma mansoni hypothetical protein 0.0102 0.0539 0.0553
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0109 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.1244 0.1536
Loa Loa (eye worm) hypothetical protein 0.1272 0.7657 0.9528
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0162 0.0815
Entamoeba histolytica hypothetical protein 0.0024 0.0064 0.0048
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0067 0.0044
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0056 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0091 0.0083
Echinococcus multilocularis cysteine protease 0.0016 0.0019 0.0009
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0064 0.0065
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0022 0.0013
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0022 0.0079
Echinococcus multilocularis carbonic anhydrase II 0.1334 0.8037 1
Onchocerca volvulus 0.0031 0.011 0.0484
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0507 0.052
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0328 0.0394
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0507 0.0618
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0067 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0056 0.007
Leishmania major carbonic anhydrase family protein, putative 0.1583 0.9553 1
Plasmodium falciparum glutathione reductase 0.0017 0.0022 0.0028
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.014 0.0344
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0064 0.0042
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0507 0.2607
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0596 0.0728
Leishmania major hypothetical protein, conserved 0.0016 0.0015 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0078 0.0178
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0177 0.0998 0.1229
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0507 0.05
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0022 0.0079
Schistosoma mansoni hypothetical protein 0.0047 0.0206 0.0204
Schistosoma mansoni ap endonuclease 0.002 0.0043 0.0033
Trypanosoma cruzi ISWI complex protein 0.0016 0.0015 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0029 0.0021
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0116 0.0055
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0091 0.0113
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0056 0.0198
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0353 0.0345
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0231 0.1326 0.132
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0164 0.019
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0164 0.019
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0102 0.0242
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0625 0.3722 0.4631
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0625 0.3722 0.4631
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0067 0.0044
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0078 0.0082
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.03 0.0359
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0596 0.0605
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0056 0.007
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0067 0.0057
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0216 0.0255
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0102 0.0242
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.005 0.0062
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0071 0.0064
Onchocerca volvulus 0.0028 0.0091 0.0382
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0067 0.0083
Loa Loa (eye worm) glutaminase 2 0.028 0.1622 0.2019
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0162 0.015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0198 0.0247
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0056 0.0046
Mycobacterium tuberculosis Possible siderophore-binding protein 0.0044 0.0187 0.0275
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0036 0.0135 0.0113
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.06 0.0922
Schistosoma mansoni kinase 0.0049 0.0218 0.0216
Echinococcus granulosus lamin 0.0026 0.0078 0.0082
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0172 0.0199
Onchocerca volvulus 0.0026 0.0078 0.0314
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0027 0.0016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0043 0.0033
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1334 0.8037 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0139 0.0158
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.033 0.0397
Schistosoma mansoni cpg binding protein 0.0032 0.0112 0.0106
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0218 0.1244 0.1536
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0596 0.0589
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0022 0.0013
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1334 0.8037 0.8411
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0808 0.1249
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0507 0.05
Schistosoma mansoni polycystin 1-related 0.004 0.0164 0.016
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0067 0.005
Echinococcus multilocularis cpg binding protein 0.0032 0.0112 0.0125
Schistosoma mansoni inositol monophosphatase 0.0036 0.014 0.0134
Loa Loa (eye worm) hypothetical protein 0.0625 0.3722 0.4631
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0018
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0137 0.017
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0206 0.0256
Echinococcus multilocularis lamin 0.0026 0.0078 0.0082
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0043 0.0054
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0102 0.0087
Plasmodium vivax glutathione reductase, putative 0.0049 0.0218 0.1565
Loa Loa (eye worm) PHD-finger family protein 0.003 0.01 0.0125
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0056 0.0046
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0199 0.0505
Leishmania major basic transcription factor 3a, putative 0.0036 0.0137 0.0131
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1334 0.8037 1
Mycobacterium tuberculosis Conserved protein 0.0025 0.0071 0.0093
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.099 0.5946 0.93
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0231 0.1326 0.132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Schistosoma mansoni carbonic anhydrase-related 0.0625 0.3722 0.3888
Schistosoma mansoni hypothetical protein 0.0047 0.0206 0.0204
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0596 0.0742
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.014 0.0159
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.1583 0.9553 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Schistosoma mansoni intermediate filament proteins 0.0026 0.0078 0.0069
Leishmania major cathepsin L-like protease 0.0063 0.03 0.0302
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0056 0.007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0043 0.004
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0067 0.0044
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0223 0.1275 0.1574
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0022 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0297 0.0275
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0036
Schistosoma mansoni inositol monophosphatase 0.0036 0.014 0.0134
Onchocerca volvulus 0.0043 0.018 0.0858
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0019 0.0011
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0081 0.0414 0.0515
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0164 0.019
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1334 0.8037 0.8411
Trypanosoma brucei polo-like protein kinase 0.0097 0.0507 0.0617
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0078 0.0178
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0064 0.0142
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0102 0.0634
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0223 0.1275 0.1323
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0216 0.0214
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0067 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0137 0.0129
Leishmania major hypothetical protein, conserved 0.0044 0.0187 0.0184
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0218 0.0256
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Loa Loa (eye worm) hypothetical protein 0.021 0.1196 0.1488
Echinococcus granulosus intermediate filament protein 0.0026 0.0078 0.0082
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0116 0.0164
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0056 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Plasmodium vivax SET domain protein, putative 0.0031 0.0109 0.0735
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.0437 0.0544
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.033 0.0326
Schistosoma mansoni hypothetical protein 0.0047 0.0206 0.0204
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0072 0.0355 0.0428
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.06 0.0922
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0022 0.0013
Loa Loa (eye worm) glutaminase 0.028 0.1622 0.2019
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0056 0.007
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.0851 0.5096 0.7969
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.021 0.0202
Echinococcus granulosus carbonic anhydrase 0.0625 0.3722 0.4623
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0056 0.007
Leishmania major carbonic anhydrase-like protein 0.1334 0.8037 0.8411
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0085 0.0437 0.0544
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.0007
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0012 0.0015
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.0437 0.053
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0137 0.0155
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0109 0.0121
Brugia malayi Bromodomain containing protein 0.0036 0.0138 0.0171
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0036
Brugia malayi PHD-finger family protein 0.003 0.01 0.0125
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0206 0.0242
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.014 0.0159
Entamoeba histolytica acetyltransferase, putative 0.0077 0.0387 0.0386
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0509 0.062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.174 0.1734
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0102 0.0242
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.0007
Trypanosoma brucei trypanothione reductase 0.0049 0.0218 0.0256
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.03 0.0359
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0056 0.0055
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0056 0.0046
Trichomonas vaginalis set domain proteins, putative 0.0243 0.1399 0.1392
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0021
Brugia malayi PHD-finger family protein 0.0031 0.0108 0.0134
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0509 0.062
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0162 0.0765
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0074 0.0369 0.0361
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0013
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0218 0.0257
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0094
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0391 0.0398
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0012 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0056 0.0046
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0071 0.0049
Brugia malayi nuclear receptor NHR-88 0.0023 0.0056 0.007
Loa Loa (eye worm) acetyltransferase 0.0151 0.0837 0.1041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0021
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0064 0.0142
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0071 0.0062
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0019 0.0024
Echinococcus multilocularis RUN 0.004 0.0164 0.019
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0056 0.0198
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0067 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.174 0.1805
Toxoplasma gondii hypothetical protein 0.0625 0.3722 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.1064 0.6392 1
Schistosoma mansoni hypothetical protein 0.0063 0.03 0.0303
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0509 0.0522
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0056 0.007
Schistosoma mansoni glutaminase 0.028 0.1622 0.1688
Echinococcus granulosus carbonic anhydrase II 0.1334 0.8037 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0022 0.0011
Schistosoma mansoni hypothetical protein 0.034 0.1989 0.2072
Schistosoma mansoni hypothetical protein 0.0021 0.0049 0.0039
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0064 0.0042
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0677 0.1042
Brugia malayi ecdysteroid receptor 0.0023 0.0056 0.007
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.01 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0056 0.0055
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0199 0.0192
Brugia malayi glutathione reductase 0.0049 0.0218 0.0271
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0043 0.0049
Onchocerca volvulus 0.0024 0.0067 0.0254
Echinococcus multilocularis hormone sensitive lipase 0.021 0.1196 0.1475
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Brugia malayi hypothetical protein 0.0026 0.0078 0.0097
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0064 0.0245
Brugia malayi nuclear hormone receptor 0.0023 0.0056 0.007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0083
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0125
Plasmodium vivax hypothetical protein, conserved 0.003 0.01 0.0673
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0297 0.0275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Echinococcus multilocularis chromobox protein 1 0.0071 0.0353 0.0425
Loa Loa (eye worm) apoptosis regulator protein 0.0081 0.0414 0.0515
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0596 0.0742
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0206 0.0242
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0071 0.0074
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0067 0.0086
Schistosoma mansoni bromodomain containing protein 0.0071 0.0351 0.0355
Echinococcus granulosus carbonic anhydrase 0.0625 0.3722 0.4623
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0081 0.0414 0.0501
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.03 0.0359
Schistosoma mansoni rab6-interacting 0.004 0.0164 0.016
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0137 0.0336
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0509 0.0634
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.014 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.1656 1 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0067 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0161 0.0156
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0036 0.0135 0.0154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0097
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.0007
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0029 0.0055
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.03 0.0359
Brugia malayi beta-NAC-like protein 0.0036 0.0137 0.017
Brugia malayi hypothetical protein 0.004 0.0164 0.0205
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Onchocerca volvulus 0.0223 0.1278 0.6719
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0102 0.0094
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0509 0.0634
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0056 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0056 0.007
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0507 0.0519
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0596 0.0589
Loa Loa (eye worm) hypothetical protein 0.0051 0.023 0.0286
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0507 0.05
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0013
Schistosoma mansoni hypothetical protein 0.0625 0.3722 0.3888
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.014 0.0132
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0011
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0081 0.0414 0.0501
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0078 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0056 0.007
Onchocerca volvulus 0.004 0.0164 0.0777
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0181 0.0173
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0199 0.0234
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.033 0.0411
Loa Loa (eye worm) inositol-1 0.0036 0.014 0.0174
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0064 0.04
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0056 0.0055
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.174 1
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0137 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0137 0.0129
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0093
Plasmodium falciparum carbonic anhydrase 0.0625 0.3722 1
Plasmodium falciparum thioredoxin reductase 0.0017 0.0022 0.0028
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0024
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0102 0.0462
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0029 0.0021
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.01 0.0239
Schistosoma mansoni hypothetical protein 0.0047 0.0206 0.0204
Schistosoma mansoni coup transcription factor 0.0023 0.0056 0.0046
Schistosoma mansoni zinc finger protein 0.0016 0.0015 0.0004
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0019 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0036
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0044 0.0187 0.0176
Schistosoma mansoni cpg binding protein 0.0032 0.0112 0.0106
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.0514 0.0626
Schistosoma mansoni hypothetical protein 0.0081 0.0414 0.0422
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0036 0.0135 0.0154
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0019 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0056 0.007
Brugia malayi isocitrate dehydrogenase 0.0015 0.0012 0.0015
Echinococcus granulosus cathepsin l1 0.0016 0.0019 0.0009
Leishmania major hypothetical protein, conserved 0.0026 0.0078 0.0069
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0022 0.0013
Chlamydia trachomatis sulfate transporter 0.0036 0.0135 0.0902
Loa Loa (eye worm) DnaJ domain-containing protein 0.0063 0.03 0.0374
Schistosoma mansoni transcription factor btf3 0.0036 0.0137 0.0131
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0353 0.0439
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0137 0.0123
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0078 0.0097
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0056 0.0055
Mycobacterium leprae PROBABLE TRANSFERASE 0.0074 0.0369 0.0321
Loa Loa (eye worm) hypothetical protein 0.0324 0.1892 0.2355
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0102 0.0462
Brugia malayi 6-phosphofructokinase 0.0111 0.0596 0.0742
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0231 0.1326 1
Schistosoma mansoni carbonic anhydrase-related 0.0625 0.3722 0.3888
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0036
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0078 0.0503
Echinococcus granulosus dnaJ subfamily B 0.0402 0.2365 0.2932
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0029 0.0027
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0507 0.0512
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0022 0.0028
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0036 0.0135 0.0154
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0509 0.0522
Brugia malayi glucose-6-phosphate dehydrogenase 0.0223 0.1275 0.1586
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0218 0.1565
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0024
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0022 0.0011
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0218 0.0322
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1334 0.8037 1
Toxoplasma gondii exonuclease III APE 0.002 0.0043 0.0085
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0625 0.3722 0.4631
Schistosoma mansoni chromobox protein 0.0071 0.0353 0.0358
Mycobacterium leprae Probable transmembrane transport protein 0.0258 0.1489 0.1501
Schistosoma mansoni carbonic anhydrase 0.0625 0.3722 0.3888
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0369 0.0361
Schistosoma mansoni hypothetical protein 0.034 0.1989 0.2072
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0288 0.0744
Brugia malayi Doublecortin family protein 0.004 0.0164 0.0205
Schistosoma mansoni hypothetical protein 0.0402 0.2365 0.2466
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0199 0.0505
Echinococcus granulosus dnaJ subfamily C 6 0.0063 0.03 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0091 0.0083
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0022 0.0011
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0146 0.0804 0.0784
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0021
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0102 0.0683
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.014 0.0159
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0216 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0056 0.0055
Mycobacterium tuberculosis Probable reductase 0.0112 0.06 0.0922
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0027 0.0018
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0056 0.0055
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0297 0.0769
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0056 0.0198
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0181 0.0173
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0146 0.0804 0.2136
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0837 0.1041
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0064 0.0142
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0187 0.0218
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0019 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0011
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0022 0.0014
Trichomonas vaginalis protein kinase inhibitor, putative 0.0063 0.03 0.0293
Echinococcus multilocularis microtubule associated protein 2 0.0707 0.4219 0.5243
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0064 0.0055
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0056 0.007
Entamoeba histolytica hypothetical protein 0.004 0.0164 0.0153
Echinococcus granulosus chromobox protein 1 0.0071 0.0353 0.0425
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0596 0.0605
Schistosoma mansoni loxhd1 0.004 0.0164 0.016
Schistosoma mansoni lipoxygenase 0.0177 0.0998 0.1033
Brugia malayi hypothetical protein 0.0324 0.1892 0.2355
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0164 0.019
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0172 0.0199
Mycobacterium ulcerans hypothetical protein 0.0025 0.0071 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0056 0.007
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0043 0.0026
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.0437 0.053
Loa Loa (eye worm) hypothetical protein 0.0047 0.0206 0.0256
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0162 0.0405
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.01 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0019 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0539 0.0671
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0043 0.0039
Loa Loa (eye worm) glutathione reductase 0.0049 0.0218 0.0271
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0808 0.0784
Mycobacterium ulcerans hypothetical protein 0.0024 0.0067 0.0044
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0596 0.334
Brugia malayi jmjC domain containing protein 0.0098 0.0514 0.0639
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0161 0.0156
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0004 0.0005
Mycobacterium ulcerans glutaminase 0.028 0.1622 0.1604
Loa Loa (eye worm) hypothetical protein 0.0073 0.0366 0.0455
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0029 0.0007
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0064 0.1157
Giardia lamblia Kinase, PLK 0.0097 0.0507 0.2824
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0019 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0056 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0509 0.062
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0067 0.0044
Brugia malayi CXXC zinc finger family protein 0.0028 0.0091 0.0113
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0081 0.0414 0.0501
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0507 0.0617
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0067 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0205
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0019 0.0019
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0596 0.0742
Plasmodium vivax vivapain-2 0.0016 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0205
Plasmodium falciparum thioredoxin reductase 0.0049 0.0218 0.0554
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0043 0.024

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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