Detailed information for compound 1149048

Basic information

Technical information
  • TDR Targets ID: 1149048
  • Name: N-[(2-methoxypyrimidin-5-yl)methyl]-N-[(5-met hylfuran-2-yl)methyl]-3-morpholin-4-ylpropan- 1-amine
  • MW: 360.451 | Formula: C19H28N4O3
  • H donors: 0 H acceptors: 2 LogP: 1.36 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ncc(cn1)CN(Cc1ccc(o1)C)CCCN1CCOCC1
  • InChi: 1S/C19H28N4O3/c1-16-4-5-18(26-16)15-23(7-3-6-22-8-10-25-11-9-22)14-17-12-20-19(24-2)21-13-17/h4-5,12-13H,3,6-11,14-15H2,1-2H3
  • InChiKey: ODZIFNAXINIWKI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(2-methoxypyrimidin-5-yl)methyl]-N-[(5-methyl-2-furyl)methyl]-3-morpholino-propan-1-amine
  • N-[(2-methoxy-5-pyrimidinyl)methyl]-N-[(5-methyl-2-furyl)methyl]-3-morpholinopropan-1-amine
  • (2-methoxypyrimidin-5-yl)methyl-[(5-methyl-2-furyl)methyl]-(3-morpholinopropyl)amine
  • N-[(2-methoxypyrimidin-5-yl)methyl]-N-[(5-methylfuran-2-yl)methyl]-3-morpholin-4-yl-propan-1-amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0752 0.4829 0.8967
Schistosoma mansoni smad1 5 8 and 0.0034 0.0136 0.0179
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0118 0.0116
Trichomonas vaginalis endoplasmin, putative 0.0033 0.0132 0.0331
Trichomonas vaginalis pyruvate kinase, putative 0.0111 0.0643 0.1891
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0035 0.0106
Brugia malayi nuclear hormone receptor 0.0031 0.0118 0.0373
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0142 0.014
Brugia malayi nuclear receptor RXR 0.0034 0.0142 0.0449
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0208 0.0285
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0039 0.019
Echinococcus multilocularis glutamate synthase 0.003 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.003 0.0115 0.0555
Brugia malayi hypothetical protein 0.002 0.0045 0.014
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0066 0.0127
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0114 0.0663 0.523
Echinococcus multilocularis protein dispatched 1 0.0105 0.0604 0.0603
Brugia malayi Cell death specification protein 2 0.002 0.0045 0.014
Brugia malayi Hsp90 protein 0.003 0.0114 0.0362
Echinococcus granulosus heat shock protein 90 0.0045 0.0214 0.0213
Schistosoma mansoni endoplasmin 0.0045 0.0214 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0343 0.1089
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0139 0.0138
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0065 0.0343 0.0341
Plasmodium falciparum endoplasmin, putative 0.0033 0.0132 0.0632
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0202 0.1239 0.1238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0136 0.043
Mycobacterium ulcerans dehydrogenase 0.003 0.0115 0.0689
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0065 0.0343 0.1086
Trypanosoma brucei Heat shock protein 83, putative 0.0045 0.0214 0.1028
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.003 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0053 0.0265 0.0839
Brugia malayi bZIP transcription factor family protein 0.002 0.0045 0.014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0208 0.0285
Schistosoma mansoni endoplasmin 0.0045 0.0214 0.0294
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.009 0.0424
Brugia malayi Pyruvate kinase, M2 isozyme 0.0111 0.0643 0.2046
Onchocerca volvulus 0.003 0.0115 0.0343
Brugia malayi hypothetical protein 0.0034 0.0142 0.0449
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0208 0.0207
Leishmania major trypanothione reductase 0.0329 0.207 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0202 0.1239 0.5984
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0065 0.0343 0.0341
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.003 0.0115 0.0549
Trichomonas vaginalis CAMK family protein kinase 0.0156 0.0935 0.2782
Brugia malayi HSF-type DNA-binding domain containing protein 0.0114 0.0662 0.2107
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0214 0.0974
Trypanosoma cruzi NADH dehydrogenase, putative 0.003 0.0115 0.0555
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0662 0.3275
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0035 0.0029
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0118 0.0373
Entamoeba histolytica disulphide oxidoreductase, putative 0.003 0.0115 0.0466
Brugia malayi conserved hypotetical protein 0.0031 0.0118 0.0373
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.003 0.0115 0.0549
Brugia malayi Cathepsin L-like precursor 0.0016 0.0024 0.0075
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.002 0.0045 0.0043
Brugia malayi hypothetical protein 0.0023 0.0066 0.0207
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0015 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Echinococcus granulosus pyruvate kinase 0.0111 0.0643 0.0642
Brugia malayi hypothetical protein 0.0013 0.0002 0.0004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0108 0.062 0.1973
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0118 0.0116
Echinococcus multilocularis beta adrenergic receptor kinase 0.0024 0.0072 0.0071
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0114 0.0341
Giardia lamblia Glutamate synthase 0.003 0.0115 0.039
Echinococcus multilocularis pyruvate kinase 0.0057 0.029 0.0288
Entamoeba histolytica hypothetical protein 0.0023 0.0066 0.0213
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0066 0.0064
Echinococcus multilocularis neuropeptide receptor A26 0.1543 1 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0066 0.0075
Brugia malayi hypothetical protein 0.0023 0.0066 0.0207
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0024 0.0116
Brugia malayi TAR-binding protein 0.02 0.1222 0.3888
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0298 0.1433
Brugia malayi nuclear receptor NHR-88 0.0065 0.0343 0.1089
Brugia malayi Cathepsin L-like precursor 0.0016 0.0024 0.0075
Loa Loa (eye worm) TAR-binding protein 0.02 0.1222 0.3886
Plasmodium falciparum glutathione reductase 0.0329 0.207 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0139 0.0138
Echinococcus multilocularis pyruvate kinase 0.0088 0.049 0.0489
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0129 0.0759 0.6029
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0214 0.1028
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0215 0.132 0.6648
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0071 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0065 0.0343 0.1086
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0066 0.0075
Brugia malayi pyruvate kinase, muscle isozyme 0.0023 0.007 0.022
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0065 0.0343 0.1034
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0066 0.0204
Schistosoma mansoni DNA polymerase eta 0.0019 0.0039 0.0036
Plasmodium falciparum pyruvate kinase 2 0.0057 0.029 0.1391
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0066 0.0064
Brugia malayi MH2 domain containing protein 0.0034 0.0136 0.0433
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0035 0.0029
Treponema pallidum NADH oxidase 0.0114 0.0663 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0114 0.0663 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0111 0.0643 0.3102
Loa Loa (eye worm) pyruvate kinase-PB 0.0077 0.0423 0.1343
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0039 0.0063
Loa Loa (eye worm) hypothetical protein 0.0051 0.0252 0.0797
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0298 0.0837
Brugia malayi Endoplasmin precursor 0.0045 0.0214 0.068
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0066 0.0064
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.003 0.0115 0.0113
Onchocerca volvulus Huntingtin homolog 0.0119 0.0695 0.2102
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.003 0.0115 0.0277
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0114 0.0663 0.3198
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0071 0.0238
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.003 0.0115 0.0113
Leishmania major hypothetical protein, conserved 0.0018 0.0035 0.0167
Schistosoma mansoni hypothetical protein 0.002 0.0045 0.0044
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0066 0.0064
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.003 0.0115 0.0546
Leishmania major DNA polymerase eta, putative 0.0019 0.0039 0.019
Brugia malayi Nuclear hormone receptor-like 1 0.0065 0.0343 0.1089
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0405 0.0576
Entamoeba histolytica hypothetical protein 0.0078 0.0426 0.2061
Brugia malayi jmjC domain containing protein 0.0018 0.0035 0.0109
Echinococcus multilocularis cysteine protease 0.0016 0.0024 0.0023
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Loa Loa (eye worm) patched family protein 0.0013 0.0002 0.0001
Leishmania major hypothetical protein, conserved 0.003 0.0115 0.0555
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0238 0.115
Loa Loa (eye worm) cysteine protease 0.0016 0.0024 0.0072
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0196 0.0524
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0043 0.0196 0.0318
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Schistosoma mansoni sulfide quinone reductase 0.003 0.0115 0.0147
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0118 0.0151
Brugia malayi MH1 domain containing protein 0.0034 0.0136 0.0433
Brugia malayi hypothetical protein 0.002 0.0045 0.014
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0138
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0114 0.0663 0.2109
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0071 0.0322
Echinococcus multilocularis musashi 0.011 0.0638 0.0637
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0035 0.0159
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0114 0.0663 0.0662
Toxoplasma gondii aldehyde dehydrogenase 0.0202 0.1239 0.5981
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0035 0.0033
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0066 0.0064
Schistosoma mansoni tar DNA-binding protein 0.02 0.1222 0.178
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0752 0.4829 0.8976
Echinococcus multilocularis transcription factor eb 0.0464 0.2952 0.2951
Schistosoma mansoni heat shock protein 0.0045 0.0214 0.0294
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0114 0.0663 0.3196
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.003 0.0115 0.0546
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0129 0.0759 0.1372
Echinococcus granulosus intermediate filament protein 0.011 0.0638 0.0637
Plasmodium vivax pyruvate kinase 2, putative 0.0057 0.029 0.1391
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.003 0.0115 0.0546
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0035 0.0159
Loa Loa (eye worm) hypothetical protein 0.0077 0.0423 0.1343
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0065 0.0343 0.1089
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.1973 0.5955
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0065 0.0343 0.1086
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0372 0.1179
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0039 0.0026
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.003 0.0115 0.0113
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0398 0.1265
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0343 0.0341
Schistosoma mansoni hypothetical protein 0.0034 0.0139 0.0184
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0142 0.0447
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0298 0.144
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.022
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.002 0.0045 0.0043
Trypanosoma cruzi heat shock protein, putative 0.003 0.0114 0.0552
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0315 0.1973 0.1972
Mycobacterium ulcerans aldehyde dehydrogenase 0.0202 0.1239 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0329 0.207 0.3821
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.1973 0.5955
Brugia malayi hypothetical protein 0.0013 0.0002 0.0004
Schistosoma mansoni glutamate synthase 0.003 0.0115 0.0147
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0024 0.0023
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0078 0.0426 0.3266
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0204
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0043 0.0196 0.0945
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.003 0.0115 0.0083
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0118 0.0373
Plasmodium falciparum ferrodoxin reductase-like protein 0.003 0.0115 0.0546
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Echinococcus multilocularis lamin 0.011 0.0638 0.0637
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0041 0.0199
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0071 0.0322
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0486 0.3093 0.4539
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.003 0.0115 0.0083
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0062 0.0061
Echinococcus granulosus transcriptional factor nfil3:e4bp4 0.002 0.0045 0.0043
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0118 0.0351
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0343 0.0341
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0118 0.0373
Echinococcus granulosus neuropeptide receptor A26 0.1543 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0138
Loa Loa (eye worm) hypothetical protein 0.011 0.0638 0.2028
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0078 0.0426 0.5675
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0114 0.0663 0.3202
Entamoeba histolytica glutamate synthase beta subunit, putative 0.003 0.0115 0.0466
Schistosoma mansoni hypothetical protein 0.0089 0.0497 0.0711
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0298 0.0948
Echinococcus granulosus histone lysine methyltransferase setb 0.0066 0.0347 0.0346
Loa Loa (eye worm) RNA binding protein 0.02 0.1222 0.3886
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0039 0.0078
Schistosoma mansoni hypothetical protein 0.0034 0.0139 0.0184
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0114 0.0663 1
Echinococcus granulosus heat shock protein 90 0.0039 0.0171 0.017
Brugia malayi Pre-SET motif family protein 0.0455 0.2888 0.9192
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.003 0.0115 0.0277
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0047 0.0046
Schistosoma mansoni heat shock protein 0.0045 0.0214 0.0294
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0066 0.0075
Echinococcus granulosus sterol regulatory element binding protein 0.0092 0.0519 0.0518
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0078 0.0426 0.205
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Schistosoma mansoni hypothetical protein 0.0034 0.0139 0.0184
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0039 0.0184
Brugia malayi hypothetical protein 0.0013 0.0002 0.0004
Giardia lamblia NADH oxidase lateral transfer candidate 0.0114 0.0663 0.3225
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0114 0.0663 0.523
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0204
Leishmania major cathepsin L-like protease 0.0016 0.0024 0.0116
Schistosoma mansoni patched 1 0.0092 0.0519 0.0743
Brugia malayi ecdysteroid receptor 0.0065 0.0343 0.1089
Mycobacterium ulcerans heat shock protein 90 0.0043 0.0196 0.1359
Onchocerca volvulus 0.0016 0.0024 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Echinococcus granulosus protocadherin 11 0.002 0.0045 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.1973 0.5955
Loa Loa (eye worm) heat shock protein 90 0.0045 0.0214 0.0677
Echinococcus granulosus sulfide:quinone oxidoreductase 0.003 0.0115 0.0113
Brugia malayi hypothetical protein 0.0013 0.0002 0.0004
Echinococcus granulosus GPCR family 2 0.0034 0.0139 0.0138
Loa Loa (eye worm) hypothetical protein 0.005 0.0241 0.0763
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0136 0.0179
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0298 0.0297
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Echinococcus granulosus dnaJ subfamily B 0.0486 0.3093 0.3092
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0277 0.1727 0.2525
Loa Loa (eye worm) hypothetical protein 0.0066 0.0347 0.1101
Echinococcus multilocularis thyroid hormone receptor alpha 0.0065 0.0343 0.0341
Schistosoma mansoni nuclear receptor 0.0031 0.0118 0.0151
Brugia malayi PXA domain containing protein 0.0023 0.0066 0.0207
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.003 0.0115 0.0549
Echinococcus granulosus ecdysone induced protein 78C 0.0065 0.0343 0.0341
Schistosoma mansoni hypothetical protein 0.002 0.0045 0.0044
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0032 0.0144
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0118 0.0151
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0114 0.0663 0.3196
Mycobacterium tuberculosis Probable oxidoreductase 0.0835 0.5377 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0298 0.1338
Onchocerca volvulus 0.0031 0.0118 0.0351
Onchocerca volvulus 0.011 0.0638 0.1931
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0519 0.1512
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Plasmodium vivax thioredoxin reductase, putative 0.0329 0.207 1
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0066 0.0064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0118 0.0151
Trichomonas vaginalis apoptosis inducing factor, putative 0.003 0.0115 0.0277
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0208 0.0285
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0039 0.0123
Trypanosoma cruzi Heat shock protein 83, putative 0.0045 0.0214 0.1034
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0078 0.0426 0.205
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0066 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.1973 0.5955
Giardia lamblia Thioredoxin reductase 0.003 0.0115 0.039
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0464 0.2952 0.9397
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0024 0.0072 0.0226
Loa Loa (eye worm) hypothetical protein 0.0215 0.132 0.4199
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0298 0.3345
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0066 0.0075
Echinococcus granulosus beta-adrenergic receptor kinase 0.0024 0.0072 0.0071
Loa Loa (eye worm) transcription factor SMAD2 0.0493 0.3142 1
Schistosoma mansoni disulfide oxidoreductase 0.003 0.0115 0.0147
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0214 0.1034
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0024 0.0116
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0092 0.0519 0.1648
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0298 0.1406
Leishmania major cathepsin L-like protease 0.0016 0.0024 0.0116
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.002 0.0045 0.0043
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0035 0.0029
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0114 0.0663 0.3196
Leishmania major DNA polymerase kappa, putative 0.0019 0.0039 0.019
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0066 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0066 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0071 0.0223
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Giardia lamblia Heat shock protein HSP 90-alpha 0.0045 0.0214 0.0903
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0426 0.067
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0024 0.0072 0.0228
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0241 0.1156
Toxoplasma gondii heat shock protein 90, putative 0.0045 0.0214 0.1026
Loa Loa (eye worm) hypothetical protein 0.0074 0.0398 0.1262
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0455 0.2888 0.9192
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0136 0.0135
Brugia malayi hypothetical protein 0.0034 0.0142 0.0449
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0072 0.0085
Toxoplasma gondii NADPH-glutathione reductase 0.0114 0.0663 0.3196
Schistosoma mansoni lamin 0.011 0.0638 0.0919
Brugia malayi hypothetical protein 0.0147 0.0876 0.2788
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0752 0.4829 0.8976
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0071 0.0084
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Onchocerca volvulus 0.0517 0.3298 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0184
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0065 0.0343 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0066 0.0127
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0078 0.0426 0.205
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0114 0.0663 0.3198
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0035 0.0033
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0065 0.0343 0.0483
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0114 0.0113
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0298 0.0297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0204
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.003 0.0115 0.0555
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0298 0.1433
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0298 0.1435
Brugia malayi nuclear hormone receptor 0.0065 0.0343 0.1089
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Brugia malayi nuclear receptor NHR-88 0.0031 0.0118 0.0373
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0326 0.1573
Leishmania major NADH dehydrogenase, putative 0.003 0.0115 0.0555
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.003 0.0115 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.022
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0298 0.0945
Mycobacterium leprae Probable pyruvate kinase PykA 0.0111 0.0643 0.1079
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0039 0.0026
Trichomonas vaginalis disulfide oxidoreductase, putative 0.003 0.0115 0.0277
Schistosoma mansoni cpg binding protein 0.0034 0.014 0.0184
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0218 0.1342 0.1957
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0204
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0024 0.0013
Plasmodium vivax heat shock protein, putative 0.0172 0.1043 0.5036
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0071 0.0238
Loa Loa (eye worm) hypothetical protein 0.003 0.0115 0.0361
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0032 0.0012
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0039 0.0038
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0114 0.0662 0.2004
Onchocerca volvulus 0.0016 0.0024 0.0067
Trypanosoma brucei beta lactamase 0.0062 0.0321 0.1547
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0035 0.0029
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.003 0.0115 0.0689
Loa Loa (eye worm) hypothetical protein 0.0277 0.1727 0.5495
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0752 0.4829 0.8976
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Plasmodium falciparum thioredoxin reductase 0.0329 0.207 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0114 0.0663 0.3198
Schistosoma mansoni thyroid hormone receptor 0.0065 0.0343 0.0483
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0326 0.1573
Schistosoma mansoni tar DNA-binding protein 0.02 0.1222 0.178
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.029 0.1402
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0315 0.1973 0.628
Echinococcus granulosus pyruvate kinase 0.0057 0.029 0.0288
Loa Loa (eye worm) pyruvate kinase 0.0111 0.0643 0.2043
Chlamydia trachomatis pyruvate kinase 0.0111 0.0643 0.9685
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.019
Trichomonas vaginalis pyruvate kinase, putative 0.0111 0.0643 0.1891
Echinococcus granulosus cpg binding protein 0.0036 0.0152 0.0151
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0024 0.0023
Leishmania major cathepsin L-like protease 0.0016 0.0024 0.0116
Loa Loa (eye worm) endoplasmin 0.0045 0.0214 0.0677
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0066 0.0064
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0171 0.0449
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0426 0.2052
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0035 0.0162
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0065 0.0343 0.0341
Trypanosoma brucei unspecified product 0.0019 0.0039 0.0184
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0039 0.0171 0.017
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0202 0.1239 0.1238
Schistosoma mansoni ap endonuclease 0.0058 0.0298 0.0418
Loa Loa (eye worm) hypothetical protein 0.0019 0.0039 0.0121
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0096
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0065 0.0343 0.1086
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Echinococcus multilocularis protocadherin 11 0.002 0.0045 0.0043
Toxoplasma gondii cathepsin CPL 0.0016 0.0024 0.0108
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0072
Loa Loa (eye worm) nuclear factor I 0.0019 0.0038 0.0117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0347 0.049
Leishmania major pyruvate kinase 0.0111 0.0643 0.3106
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.003 0.0115 0.0466
Loa Loa (eye worm) hypothetical protein 0.0111 0.0643 0.2043
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0298 0.144
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0084 0.0465 0.1478
Echinococcus multilocularis cpg binding protein 0.0036 0.0152 0.0151
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0096
Brugia malayi MH2 domain containing protein 0.0015 0.0015 0.0046
Echinococcus granulosus dna polymerase kappa 0.0019 0.0039 0.0038
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0115 0.0549
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0066 0.0064
Echinococcus multilocularis dnaJ subfamily B 0.0486 0.3093 0.3092
Echinococcus multilocularis dna polymerase eta 0.0019 0.0039 0.0038
Leishmania major pyruvate kinase 0.0111 0.0643 0.3106
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0343 0.1089
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0024 0.0108
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0015 0.0014
Brugia malayi jmjC domain containing protein 0.0018 0.0035 0.0109
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.0638 0.2028
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.003 0.0115 0.0113
Onchocerca volvulus 0.0065 0.0343 0.1034
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0066 0.0075
Brugia malayi CHE-14 protein 0.0092 0.0519 0.165
Mycobacterium ulcerans aldehyde dehydrogenase 0.0202 0.1239 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0117
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0114 0.0463
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0024 0.0072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0106
Onchocerca volvulus 0.0016 0.0024 0.0067
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Onchocerca volvulus Pyruvate kinase homolog 0.0111 0.0643 0.1946
Brugia malayi jmjC domain containing protein 0.0068 0.0359 0.1141
Brugia malayi jmjC domain containing protein 0.0018 0.0035 0.0109
Loa Loa (eye worm) pyruvate kinase 0.0111 0.0643 0.2043
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0015 0.0043
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0202 0.1239 0.2267
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0118 0.0373
Loa Loa (eye worm) glutathione reductase 0.0329 0.207 0.6588
Schistosoma mansoni pyruvate kinase 0.0057 0.029 0.0405
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0138
Schistosoma mansoni nuclear receptor 0.0031 0.0118 0.0151
Plasmodium vivax vivapain-2 0.0016 0.0024 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0315 0.1973 0.9533
Onchocerca volvulus 0.0277 0.1727 0.5234
Echinococcus multilocularis pyruvate kinase 0.0111 0.0643 0.0642
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0065 0.0343 0.1089
Leishmania major heat shock protein, putative 0.003 0.0114 0.0552
Plasmodium falciparum pyruvate kinase 0.0111 0.0643 0.31
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0024 0.0067
Brugia malayi PXA domain containing protein 0.0023 0.0066 0.0207
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0066 0.0075
Brugia malayi Cell death specification protein 2 0.002 0.0045 0.014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0204
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0303 0.0961
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0204
Onchocerca volvulus 0.0234 0.1445 0.4379
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0132 0.0331
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0277 0.1727 0.5496
Brugia malayi hypothetical protein 0.002 0.0045 0.014
Onchocerca volvulus 0.0024 0.0071 0.0209
Echinococcus multilocularis heat shock protein 90 0.0045 0.0214 0.0213
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0015 0.0046
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0063 0.0327 0.0325
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0214 0.1028
Brugia malayi protein C24B5.3 0.0013 0.0002 0.0004
Toxoplasma gondii pyruvate kinase PyKII 0.0057 0.029 0.1391
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0114 0.0663 0.3202
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0114 0.0663 0.3196
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0184
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0062 0.0061
Entamoeba histolytica hypothetical protein 0.002 0.0045 0.0105
Brugia malayi intermediate filament protein 0.011 0.0638 0.203
Entamoeba histolytica serine/threonine protein kinase, putative 0.0315 0.1973 1
Treponema pallidum heat shock protein 90 0.0043 0.0196 0.1477
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0298 0.0837
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0241 0.1164
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0835 0.5377 1
Echinococcus multilocularis endoplasmin 0.0043 0.0196 0.0194
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0035 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0347 0.049
Loa Loa (eye worm) hypothetical protein 0.0462 0.2937 0.935
Onchocerca volvulus Pyruvate kinase homolog 0.0111 0.0643 0.1946
Trichomonas vaginalis mercuric reductase, putative 0.0114 0.0663 0.1952
Schistosoma mansoni aldehyde dehydrogenase 0.0202 0.1239 0.1805
Schistosoma mansoni serine/threonine protein kinase 0.0315 0.1973 0.2888
Brugia malayi glutathione reductase 0.0329 0.207 0.6589
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) pax transcription factor protein 2 0.0234 0.1445 0.4597
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.003 0.0115 0.0689
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0171 0.0681
Brugia malayi Pax transcription factor protein 2 0.0234 0.1445 0.4599
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0031 0.0118 0.0116
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0092 0.0519 0.1648
Brugia malayi photoreceptor-specific nuclear receptor 0.0065 0.0343 0.1089
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0065 0.0343 0.0483
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.1973 0.5955
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0118 0.0151
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.003 0.0115 0.0689
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0114 0.0663 0.1191
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0043 0.0196 0.1477
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.003 0.0115 0.0364
Toxoplasma gondii pyruvate kinase PyK1 0.0111 0.0643 0.31
Echinococcus multilocularis pyruvate kinase 0.0057 0.029 0.0288
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0039 0.0036
Onchocerca volvulus Pyruvate kinase homolog 0.0111 0.0643 0.1946
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.003 0.0115 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0343 0.1089
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0035 0.0106
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0662 0.3275
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0118 0.0116
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0136 0.0135
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0071 0.0341
Echinococcus multilocularis L aminoadipate semialdehyde 0.0277 0.1727 0.1726
Loa Loa (eye worm) steroid hormone receptor 0.0065 0.0343 0.1086
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0136 0.043
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0139 0.0138
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0024 0.0108
Brugia malayi RNA recognition motif domain containing protein 0.02 0.1222 0.3888
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Plasmodium vivax vivapain-2 0.0016 0.0024 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0035 0.0106
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0171 0.0826
Echinococcus multilocularis X box binding protein 1 0.0617 0.3952 0.3952
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0084 0.0465 0.1478
Loa Loa (eye worm) hypothetical protein 0.0108 0.0625 0.1986
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0035 0.0159
Brugia malayi tailless protein 0.0031 0.0118 0.0373
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0114 0.0663 0.523
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0039 0.0047
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.003 0.0115 0.0113
Brugia malayi Myosin head containing protein 0.0013 0.0002 0.0004
Brugia malayi Pre-SET motif family protein 0.0066 0.0347 0.1103
Brugia malayi Cathepsin L-like precursor 0.0016 0.0024 0.0075
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0114 0.0663 0.3198
Brugia malayi MH1 domain containing protein 0.0034 0.0136 0.0433
Trypanosoma cruzi polo-like protein kinase, putative 0.0315 0.1973 0.9533
Echinococcus granulosus Smad4 0.0034 0.0136 0.0135
Brugia malayi Steroid receptor seven-up type 2 0.0065 0.0343 0.1089
Brugia malayi hypothetical protein 0.0031 0.0118 0.0373
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0114 0.0546
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Trypanosoma brucei pyruvate kinase 1 0.0111 0.0643 0.3102
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0071 0.0322
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0039 0.0047
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0114 0.0663 0.0956
Echinococcus multilocularis GPCR, family 2 0.0034 0.0139 0.0138
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0078 0.0426 0.3266
Schistosoma mansoni coup transcription factor 0.0065 0.0343 0.0483
Schistosoma mansoni glutamate synthase 0.003 0.0115 0.0147
Onchocerca volvulus 0.0016 0.0024 0.0067
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Schistosoma mansoni smad1 5 8 and 0.0034 0.0136 0.0179
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0024 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.003 0.0115 0.0277
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.003 0.0115 0.0546
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.003 0.0115 0.0546
Onchocerca volvulus Bile acid receptor homolog 0.0065 0.0343 0.1034
Onchocerca volvulus 0.0034 0.014 0.0418
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0118 0.0373
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0039 0.0121
Toxoplasma gondii exonuclease III APE 0.0058 0.0298 0.1433
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0142 0.014
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0066 0.0347 0.049
Schistosoma mansoni hypothetical protein 0.0089 0.0497 0.0711
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0071 0.0341
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0024 0.0108
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0015 0.0015 0.004
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Loa Loa (eye worm) DR-78 0.0031 0.0118 0.037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0065 0.0343 0.1089
Echinococcus granulosus heat shock protein 0.0045 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0208 0.0207
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0372 0.0526
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Loa Loa (eye worm) bZIP transcription factor family protein 0.002 0.0045 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0065 0.0343 0.1089
Schistosoma mansoni tar DNA-binding protein 0.02 0.1222 0.178
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.003 0.0115 0.0546
Mycobacterium ulcerans hypothetical protein 0.003 0.0115 0.0689
Echinococcus multilocularis ecdysone induced protein 78C 0.0065 0.0343 0.0341
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0065 0.0343 0.0341
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0071 0.0341
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Schistosoma mansoni Smad4 0.0034 0.0136 0.0179
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0355 0.1707
Brugia malayi Patched protein homolog 1 0.0013 0.0002 0.0004
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0241 0.1156
Plasmodium vivax JmjC domain containing protein 0.0018 0.0035 0.0159
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0066 0.0207
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.003 0.0115 0.0167
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0447
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Trypanosoma brucei trypanothione reductase 0.0329 0.207 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0493 0.3142 1
Schistosoma mansoni aldehyde dehydrogenase 0.0202 0.1239 0.1805
Trichomonas vaginalis disulfide oxidoreductase, putative 0.003 0.0115 0.0277
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0118 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0066 0.0127
Loa Loa (eye worm) patched family protein 0.0013 0.0002 0.0001
Brugia malayi jmjC domain containing protein 0.007 0.0372 0.1182
Onchocerca volvulus 0.002 0.0045 0.013
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0835 0.5377 1
Echinococcus granulosus lamin 0.011 0.0638 0.0637
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0039 0.0038
Trichomonas vaginalis set domain proteins, putative 0.0517 0.3298 1
Schistosoma mansoni retinoic acid receptor RXR 0.0065 0.0343 0.0483
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0139 0.0442
Leishmania major cathepsin L-like protease 0.0063 0.0326 0.1573
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0114 0.0663 0.3202
Mycobacterium ulcerans lipoprotein LpqF 0.0062 0.0321 0.2399
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.003 0.0115 0.0466
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.1973 0.5955
Brugia malayi glutamate synthase 0.003 0.0115 0.0364
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0447
Loa Loa (eye worm) fibroinase 0.0016 0.0024 0.0072
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0142 0.0187
Echinococcus multilocularis FTZ F1 alpha 0.0065 0.0343 0.0341
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0136 0.0135
Schistosoma mansoni thyroid hormone receptor 0.0065 0.0343 0.0483
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0114 0.0663 1
Schistosoma mansoni transcriptional factor nfil3/e4bp4 0.002 0.0045 0.0044
Brugia malayi Smad1 0.0034 0.0136 0.0433
Trypanosoma cruzi pyruvate kinase 2, putative 0.0111 0.0643 0.3106
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.003 0.0115 0.0361
Schistosoma mansoni steroid hormone receptor ad4bp 0.0065 0.0343 0.0483
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0108 0.062 0.1973
Schistosoma mansoni glutamate synthase 0.003 0.0115 0.0147
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.022
Echinococcus granulosus smad 0.0034 0.0136 0.0135
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0118 0.0116
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0066 0.0064
Plasmodium vivax ferrodoxin reductase, putative 0.003 0.0115 0.0546
Echinococcus granulosus tar DNA binding protein 0.02 0.1222 0.1221
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0039 0.0038
Plasmodium vivax heat shock protein 86, putative 0.0045 0.0214 0.1026
Brugia malayi Cathepsin L-like precursor 0.0016 0.0024 0.0075
Schistosoma mansoni jumonji domain containing protein 0.0068 0.0359 0.0507
Trypanosoma cruzi trypanothione reductase, putative 0.0329 0.207 1
Trichomonas vaginalis heat shock protein, putative 0.0026 0.009 0.02
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0096
Schistosoma mansoni ap endonuclease 0.0058 0.0298 0.0418
Onchocerca volvulus 0.0066 0.0347 0.1048
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0078 0.0426 0.5675
Loa Loa (eye worm) programmed cell death 8 0.003 0.0115 0.0361
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Trypanosoma cruzi NADH dehydrogenase, putative 0.003 0.0115 0.0555
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0078 0.0426 0.0748
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Loa Loa (eye worm) pyruvate kinase 0.0111 0.0643 0.2043
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0071 0.0223
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.003 0.0115 0.0466
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0298 0.2208
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0462 0.2937 0.935
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0072 0.0085
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0118 0.0116
Brugia malayi nuclear receptor RXR 0.0031 0.0118 0.0373
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.003 0.0115 0.039
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0015 0.0043
Echinococcus granulosus pyruvate kinase 0.0057 0.029 0.0288
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Echinococcus multilocularis transcriptional factor nfil3:e4bp4 0.002 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0447
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0065 0.0343 0.0341
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0265 0.0264
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0118 0.037
Schistosoma mansoni hypothetical protein 0.0074 0.0398 0.0565
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.014 0.0441
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.003 0.0115 0.0555
Echinococcus multilocularis lamin dm0 0.011 0.0638 0.0637
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Echinococcus multilocularis ccaat enhancer binding protein delta ccaat enhancer binding protein beta 0.002 0.0045 0.0043
Onchocerca volvulus 0.002 0.0045 0.013
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0118 0.0373
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Plasmodium falciparum heat shock protein 90 0.0045 0.0214 0.1026
Giardia lamblia Grp94/Hsp90 0.0043 0.0196 0.0809
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0106
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0035 0.0033
Leishmania major hypothetical protein, conserved 0.003 0.0115 0.0555
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0043 0.0196 0.0236
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0024 0.0067
Brugia malayi jmjC domain containing protein 0.0018 0.0035 0.0109
Schistosoma mansoni hypothetical protein 0.0034 0.0139 0.0184
Echinococcus granulosus lamin dm0 0.011 0.0638 0.0637
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0066 0.0207
Loa Loa (eye worm) hypothetical protein 0.0147 0.0876 0.2786
Plasmodium vivax endoplasmin, putative 0.0045 0.0214 0.1026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Entamoeba histolytica thioredoxin reductase, putative 0.003 0.0115 0.0466
Echinococcus multilocularis expressed conserved protein 0.0202 0.1235 0.1234
Mycobacterium ulcerans hypothetical protein 0.0024 0.0071 0.0322
Schistosoma mansoni pyruvate kinase 0.0111 0.0643 0.0926
Echinococcus multilocularis expressed protein 0.0443 0.2815 0.2814
Brugia malayi hypothetical protein 0.0119 0.0695 0.221
Trypanosoma brucei NADH dehydrogenase 0.003 0.0115 0.0549
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0066 0.0075
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0035 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0115 0.0555
Mycobacterium tuberculosis Probable dehydrogenase 0.0752 0.4829 0.8976
Echinococcus multilocularis smad 0.0034 0.0136 0.0135
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0066 0.0075
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.019
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0066 0.0064
Loa Loa (eye worm) hypothetical protein 0.0114 0.0662 0.2105
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0265 0.0264
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.003 0.0115 0.0555
Echinococcus multilocularis sterol regulatory element binding protein 0.0092 0.0519 0.0518
Schistosoma mansoni smad 0.0034 0.0136 0.0179
Echinococcus multilocularis neuropeptide s receptor 0.1543 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0066 0.0347 0.0346
Echinococcus granulosus endoplasmin 0.0043 0.0196 0.0194
Brugia malayi hypothetical protein 0.0031 0.0118 0.0373
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0024 0.0013
Brugia malayi protein C24B5.3 0.0013 0.0002 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0066 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0065 0.0343 0.1086
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0114 0.0663 0.3202
Schistosoma mansoni par domain protein 0.002 0.0045 0.0044
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.003 0.0115 0.0549
Leishmania major phosphopantetheinyl transferase-like protein 0.0078 0.0426 0.2057
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.003 0.0115 0.0546
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.003 0.0115 0.0555
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0208 0.0207
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0372 0.0526
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.003 0.0115 0.0113
Brugia malayi Patched related family protein 4 0.0013 0.0002 0.0004
Onchocerca volvulus 0.0016 0.0024 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0065 0.0343 0.1086
Brugia malayi MH1 domain containing protein 0.0019 0.0038 0.012
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0447
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.003 0.0115 0.0689
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0114 0.0663 0.0662
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0347 0.049
Echinococcus granulosus X box binding protein 1 0.0617 0.3952 0.3952
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0066 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0066 0.0127
Schistosoma mansoni tar DNA-binding protein 0.02 0.1222 0.178
Loa Loa (eye worm) patched family protein 0.0013 0.0002 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0039 0.0123
Brugia malayi hypothetical protein 0.005 0.0241 0.0766
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.0638 0.203
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.0359 0.0358
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0035 0.0167
Schistosoma mansoni tar DNA-binding protein 0.02 0.1222 0.178
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0096
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0118 0.0116
Brugia malayi Cathepsin L-like precursor 0.0016 0.0024 0.0075
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0071 0.0322
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0078 0.0426 0.205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Echinococcus granulosus Protein patched homolog 1 0.0092 0.0519 0.0518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Toxoplasma gondii thioredoxin reductase 0.0329 0.207 1
Brugia malayi Hepatic leukemia factor 0.002 0.0045 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.003 0.0115 0.0083
Schistosoma mansoni hypothetical protein 0.0089 0.0497 0.0711
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.003 0.0115 0.0113
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0298 0.3345
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0065 0.0343 0.0341
Trichomonas vaginalis disulfide oxidoreductase, putative 0.003 0.0115 0.0277
Trypanosoma cruzi trypanothione reductase, putative 0.0114 0.0663 0.3202
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0303 0.0964
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0065 0.0343 0.0483
Schistosoma mansoni zinc finger protein 0.0031 0.0118 0.0151
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0118 0.0116
Echinococcus granulosus geminin 0.0896 0.5776 0.5775
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0326 0.1573
Giardia lamblia Kinase, PLK 0.0315 0.1973 1
Toxoplasma gondii Hsp90 domain-containing protein 0.0172 0.1043 0.5036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0343 0.1089
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0066 0.0075
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0118 0.0116
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0118 0.0116
Echinococcus multilocularis geminin 0.0896 0.5776 0.5775
Loa Loa (eye worm) hypothetical protein 0.0108 0.062 0.1971
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0071 0.0322
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0114 0.0663 0.3196
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0065 0.0343 0.1089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0343 0.0341
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.003 0.0115 0.0689
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0139 0.0442
Trichomonas vaginalis disulfide oxidoreductase, putative 0.003 0.0115 0.0277
Onchocerca volvulus 0.002 0.0045 0.013
Brugia malayi hypothetical protein 0.0032 0.0126 0.04
Trichomonas vaginalis glutathione reductase, putative 0.0114 0.0663 0.1952
Schistosoma mansoni pyruvate kinase 0.0111 0.0643 0.0926
Echinococcus granulosus FTZ F1 alpha 0.0065 0.0343 0.0341
Loa Loa (eye worm) hypothetical protein 0.0113 0.0654 0.2079
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.003 0.0115 0.0113
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0118 0.0116
Echinococcus granulosus pyruvate kinase 0.0111 0.0643 0.0642
Loa Loa (eye worm) intermediate filament protein 0.011 0.0638 0.2028
Schistosoma mansoni kinase 0.016 0.0962 0.1397
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0035 0.0033
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.003 0.0115 0.0546
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0024 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0208 0.0658
Echinococcus granulosus cathepsin l1 0.0016 0.0024 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0065 0.0343 0.1086
Leishmania major cathepsin L-like protease 0.0063 0.0326 0.1573
Toxoplasma gondii selenide, water dikinase 0.003 0.0115 0.0546
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0241 0.1156
Echinococcus granulosus phd:f box containing protein 0.0018 0.0035 0.0033
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0066 0.0064
Trypanosoma cruzi polo-like protein kinase, putative 0.0315 0.1973 0.9533
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0343 0.1089
Onchocerca volvulus 0.002 0.0045 0.013
Onchocerca volvulus 0.0147 0.0876 0.2653
Echinococcus multilocularis protocadherin 11 0.002 0.0045 0.0043
Echinococcus multilocularis pyruvate kinase 0.0111 0.0643 0.0642
Schistosoma mansoni thyrotroph embryonic factor related 0.002 0.0045 0.0044
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.003 0.0115 0.0167
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0138
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0039 0.019
Echinococcus multilocularis cysteine protease 0.0016 0.0024 0.0023
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0062 0.0321 0.0553
Echinococcus granulosus transcription factor eb 0.0464 0.2952 0.2951
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0066 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0106
Loa Loa (eye worm) hypothetical protein 0.0119 0.0695 0.2208
Mycobacterium ulcerans pyruvate kinase 0.0111 0.0643 0.5065
Schistosoma mansoni hypothetical protein 0.0022 0.0062 0.007
Plasmodium vivax heat shock protein 90, putative 0.003 0.0114 0.0543
Echinococcus granulosus ccaat enhancer binding protein delta 0.002 0.0045 0.0043
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0298 0.144
Brugia malayi Pyruvate kinase, muscle isozyme 0.0111 0.0643 0.2046
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0315 0.1973 0.1972
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0343 0.0483
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0118 0.0351
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0065 0.0343 0.0483
Entamoeba histolytica hypothetical protein 0.0023 0.0066 0.0213
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0115 0.0555
Echinococcus granulosus Niemann Pick C1 protein 0.0215 0.132 0.1319
Brugia malayi Niemann-Pick C1 protein precursor 0.0215 0.132 0.42
Loa Loa (eye worm) cell death specification protein 2 0.002 0.0045 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0072 0.0085
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0039 0.0184
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0065 0.0343 0.1089
Mycobacterium ulcerans NADH dehydrogenase 0.003 0.0115 0.0689
Plasmodium falciparum glutathione reductase 0.0114 0.0663 0.3196
Leishmania major hypothetical protein, conserved 0.005 0.0241 0.1164
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Brugia malayi Cell death specification protein 2 0.002 0.0045 0.014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0111 0.0643 0.1154
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.003 0.0115 0.0555
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0896 0.5776 0.8496
Loa Loa (eye worm) Smad1 0.0034 0.0136 0.043
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0142 0.0449
Entamoeba histolytica hypothetical protein 0.0023 0.0066 0.0213
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.003 0.0115 0.0083
Schistosoma mansoni hypothetical protein 0.003 0.0115 0.0147
Echinococcus granulosus pyruvate kinase 0.0057 0.029 0.0288
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Schistosoma mansoni hypothetical protein 0.0617 0.3952 0.5807
Plasmodium falciparum heat shock protein 90, putative 0.0172 0.1043 0.5036
Trypanosoma cruzi pyruvate kinase 2, putative 0.0111 0.0643 0.3106
Echinococcus granulosus expressed protein 0.0443 0.2815 0.2814
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.003 0.0115 0.0167
Echinococcus granulosus lysine specific demethylase 5A 0.007 0.0372 0.037
Plasmodium vivax glutathione reductase, putative 0.0329 0.207 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0024 0.0023
Leishmania major cathepsin L-like protease 0.0016 0.0024 0.0116
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0136 0.0135
Brugia malayi MH2 domain containing protein 0.0493 0.3142 1
Loa Loa (eye worm) patched family protein 0.0013 0.0002 0.0001
Leishmania major cathepsin L-like protease 0.0016 0.0024 0.0116
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0241 0.1156
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0065 0.0343 0.0341
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0078 0.0426 0.6244
Onchocerca volvulus Protein ultraspiracle homolog 0.0065 0.0343 0.1034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0039 0.019
Onchocerca volvulus 0.0016 0.0024 0.0067
Loa Loa (eye worm) patched family protein 0.0013 0.0002 0.0001
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0035 0.0033
Plasmodium vivax SET domain protein, putative 0.0066 0.0347 0.1669
Plasmodium vivax pyruvate kinase, putative 0.0111 0.0643 0.31
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.003 0.0115 0.0546
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.003 0.0115 0.0689
Chlamydia trachomatis thioredoxin reductase 0.003 0.0115 0.1317
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0139 0.0138
Echinococcus multilocularis pyruvate kinase 0.0057 0.029 0.0288
Trypanosoma brucei heat shock protein, putative 0.0045 0.0214 0.1028
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0241 0.1159
Echinococcus granulosus dna polymerase eta 0.0019 0.0039 0.0038
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0032 0.0144
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0066 0.0207
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.003 0.0115 0.0689
Echinococcus multilocularis tar DNA binding protein 0.02 0.1222 0.1221
Loa Loa (eye worm) hypothetical protein 0.0065 0.0343 0.1086
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.003 0.0115 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0343 0.1089
Loa Loa (eye worm) ctsf protein 0.0016 0.0024 0.0072
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0024 0.0072 0.0226
Leishmania major hypothetical protein, conserved 0.003 0.0115 0.0555
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0359 0.0358
Toxoplasma gondii heat shock protein HSP90 0.0045 0.0214 0.1026
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0065 0.0343 0.1089
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0066 0.0064
Schistosoma mansoni smad1 5 8 and 0.0034 0.0136 0.0179
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0024 0.0067
Giardia lamblia Hypothetical protein 0.002 0.0045 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0138
Loa Loa (eye worm) heat shock protein 75 0.003 0.0114 0.0359
Schistosoma mansoni RAR-like nuclear receptor 0.0065 0.0343 0.0483
Echinococcus multilocularis heat shock protein 90 0.0039 0.0171 0.017
Brugia malayi Patched related family protein 10 0.0013 0.0002 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0326 0.1573
Loa Loa (eye worm) pyruvate kinase 0.0023 0.007 0.0218
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.037
Onchocerca volvulus 0.0016 0.0024 0.0067
Mycobacterium ulcerans monoxygenase 0.003 0.0115 0.0689
Mycobacterium ulcerans glutamate synthase subunit beta 0.003 0.0115 0.0689
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0065 0.0343 0.0341
Onchocerca volvulus 0.0031 0.0118 0.0351
Schistosoma mansoni hypothetical protein 0.0896 0.5776 0.8496
Brugia malayi ecdysone receptor 0.0031 0.0118 0.0373
Trypanosoma cruzi heat shock protein 90, putative 0.0045 0.0214 0.1034
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0024 0.0075
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0035 0.0167
Plasmodium falciparum thioredoxin reductase 0.0114 0.0663 0.3196
Schistosoma mansoni sulfide quinone reductase 0.003 0.0115 0.0147
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0065 0.0343 0.0341
Brugia malayi pyruvate kinase 0.0023 0.007 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0315 0.1973 0.5955
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0214 0.1034
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.002 0.0045 0.0043
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0066 0.0207
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0208 0.0207
Loa Loa (eye worm) thioredoxin reductase 0.0329 0.207 0.6588
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.003 0.0115 0.0364
Echinococcus multilocularis Smad4 0.0034 0.0136 0.0135
Schistosoma mansoni cpg binding protein 0.0036 0.0152 0.0203
Echinococcus multilocularis heat shock protein 0.0045 0.0214 0.0213
Echinococcus granulosus protocadherin 11 0.002 0.0045 0.0043
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.02 0.1222 0.3886
Echinococcus multilocularis thioredoxin glutathione reductase 0.0331 0.2081 0.208
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Giardia lamblia Pyruvate kinase 0.0057 0.029 0.1294
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0066 0.0347 0.0346
Trichomonas vaginalis CAMK family protein kinase 0.0156 0.0935 0.2782
Loa Loa (eye worm) hypothetical protein 0.0034 0.0142 0.0447
Echinococcus granulosus L aminoadipate semialdehyde 0.0277 0.1727 0.1726
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0343 0.0341
Echinococcus multilocularis protein patched 0.0092 0.0519 0.0518
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0114 0.0543
Echinococcus multilocularis Niemann Pick C1 protein 0.0307 0.1922 0.1921
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0039 0.0036
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.003 0.0115 0.0364
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0096
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.003 0.0115 0.0277
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0035 0.0033
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0142 0.0187
Echinococcus granulosus thioredoxin glutathione reductase 0.0331 0.2081 0.208
Brugia malayi heat shock protein 90 0.0045 0.0214 0.068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Giardia lamblia Pyruvate kinase 0.0111 0.0643 0.3122
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0138
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0062 0.0321 0.0472
Loa Loa (eye worm) hypothetical protein 0.0051 0.0252 0.0797
Brugia malayi MH2 domain containing protein 0.0034 0.0136 0.0433
Brugia malayi CXXC zinc finger family protein 0.0034 0.014 0.0443
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Brugia malayi Patched related family protein 12 0.0013 0.0002 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0039 0.0184
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0208 0.0661
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0118 0.0116
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0118 0.037
Brugia malayi nuclear receptor NHR-67 0.0031 0.0118 0.0373
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0047 0.0046
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0066 0.0207
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0071 0.0322
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0071 0.0084
Entamoeba histolytica heat shock transcription factor, putative 0.0114 0.0662 0.3275
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0359 0.0358
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0066 0.0347 0.1669
Brugia malayi Cathepsin L-like precursor 0.0016 0.0024 0.0075
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0139 0.0439
Onchocerca volvulus Huntingtin homolog 0.0119 0.0695 0.2102
Trichomonas vaginalis glutamate synthase, putative 0.003 0.0115 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0066 0.0127
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0196 0.0524
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0071 0.0223
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0043
Leishmania major cathepsin L-like protease 0.0063 0.0326 0.1573
Loa Loa (eye worm) hypothetical protein 0.0119 0.0695 0.2208
Mycobacterium ulcerans ferredoxin reductase 0.003 0.0115 0.0689
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0752 0.4829 0.8976
Brugia malayi RNA binding protein 0.02 0.1222 0.3888
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0214 0.0974
Entamoeba histolytica pyruvate kinase, putative 0.0077 0.0423 0.2048
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0241 0.1164
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0071 0.0322
Brugia malayi Thioredoxin reductase 0.0329 0.207 0.6589
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Schistosoma mansoni intermediate filament proteins 0.011 0.0638 0.0919
Echinococcus multilocularis Niemann Pick C1 protein 0.0215 0.132 0.1319
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0795 0.5114 0.5114
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.003 0.0115 0.0555
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0114 0.0113
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0024 0.0072
Onchocerca volvulus 0.011 0.0638 0.1931
Echinococcus granulosus Niemann Pick C1 protein 0.0307 0.1922 0.1921
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0066 0.0064
Echinococcus granulosus glutamate synthase 0.003 0.0115 0.0113
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0066 0.0064
Leishmania major heat shock protein 83-1 0.0045 0.0214 0.1034
Brugia malayi Patched family protein 0.0013 0.0002 0.0004
Schistosoma mansoni heat shock protein 0.003 0.0114 0.0146
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0298 0.051
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0108 0.062 0.1971
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.003 0.0115 0.0113
Brugia malayi MH1 domain containing protein 0.0019 0.0038 0.012
Mycobacterium tuberculosis Probable reductase 0.0752 0.4829 0.8976
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Trichomonas vaginalis glutamate synthase, putative 0.003 0.0115 0.0277
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0034 0.0136 0.0433
Entamoeba histolytica glutamate synthase beta subunit, putative 0.003 0.0115 0.0466
Onchocerca volvulus Serine\/threonine kinase homolog 0.0315 0.1973 0.5982
Echinococcus granulosus expressed conserved protein 0.0202 0.1235 0.1234
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0039 0.0063
Schistosoma mansoni lamin 0.011 0.0638 0.0919
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.003 0.0115 0.0167
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.002 0.0045 0.0043
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0214 0.1034
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0065 0.0343 0.0483
Loa Loa (eye worm) hypothetical protein 0.0034 0.0139 0.0439
Trypanosoma brucei polo-like protein kinase 0.0315 0.1973 0.9532
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0118 0.0151
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.003 0.0115 0.0277
Schistosoma mansoni cpg binding protein 0.0036 0.0152 0.0203
Trichomonas vaginalis disulfide oxidoreductase, putative 0.003 0.0115 0.0277
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0171 0.0826
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0114 0.0663 0.3202
Brugia malayi serine/threonine-protein kinase plk-2 0.0315 0.1973 0.6281
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0066 0.0064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0202 0.1239 1
Brugia malayi steroid hormone receptor 0.0065 0.0343 0.1089
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0142 0.0449
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0326 0.1568
Schistosoma mansoni hypothetical protein 0.0089 0.0497 0.0711
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0835 0.5377 1
Trichomonas vaginalis heat shock protein, putative 0.0045 0.0214 0.058
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0066 0.0204
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0066 0.0204

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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