Detailed information for compound 1343492

Basic information

Technical information
  • TDR Targets ID: 1343492
  • Name: 2-[2-[4,6-dioxo-2,5-di(phenyl)-3a,6a-dihydro- 3H-pyrrolo[3,4-d][1,2]oxazol-3-yl]phenoxy]ace tic acid
  • MW: 444.436 | Formula: C25H20N2O6
  • H donors: 1 H acceptors: 4 LogP: 3.6 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)COc1ccccc1C1N(OC2C1C(=O)N(C2=O)c1ccccc1)c1ccccc1
  • InChi: 1S/C25H20N2O6/c28-20(29)15-32-19-14-8-7-13-18(19)22-21-23(33-27(22)17-11-5-2-6-12-17)25(31)26(24(21)30)16-9-3-1-4-10-16/h1-14,21-23H,15H2,(H,28,29)
  • InChiKey: QRDNEVXKPVQSKQ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-[2-[4,6-dioxo-2,5-di(phenyl)-3a,6a-dihydro-3H-pyrrolo[3,4-d]isoxazol-3-yl]phenoxy]acetic acid
  • 2-[2-[4,6-diketo-2,5-di(phenyl)-3a,6a-dihydro-3H-pyrrolo[3,4-d]isoxazol-3-yl]phenoxy]acetic acid
  • 2-[2-[4,6-dioxo-2,5-di(phenyl)-3a,6a-dihydro-3H-pyrrolo[3,4-d][1,2]oxazol-3-yl]phenoxy]ethanoic acid
  • MLS000041756
  • SMR000046835

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens multiple endocrine neoplasia I No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) calmodulin-like protein 0.0049 0.0102 0.0334
Brugia malayi RNA, U transporter 1 0.0099 0.0237 0.0781
Echinococcus granulosus cathepsin b 0.1143 0.3033 1
Trypanosoma cruzi I/6 autoantigen, putative 0.0049 0.0102 0.0297
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0105 0.0254 0.2312
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0001 0.0002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0001 0.0001
Echinococcus granulosus cathepsin L cysteine protease 0.0152 0.0379 0.1249
Entamoeba histolytica grainin 2 0.0049 0.0102 0.1345
Loa Loa (eye worm) hypothetical protein 0.1143 0.3033 1
Onchocerca volvulus 0.0264 0.0679 0.4461
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0013 0.0007 0.0022
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0047 0.0117
Brugia malayi Cathepsin L-like precursor 0.0076 0.0176 0.0581
Mycobacterium leprae PROBABLE HYDROLASE 0.0026 0.0042 0.5
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0012 0.0011
Echinococcus multilocularis cpg binding protein 0.0037 0.007 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0379 0.3508
Schistosoma mansoni reticulocalbin 0.0049 0.0102 0.0101
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Brugia malayi hypothetical protein 0.0015 0.0012 0.0039
Onchocerca volvulus 0.0264 0.0679 0.4461
Onchocerca volvulus 0.0035 0.0065 0.0419
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0076 0.0174 0.154
Echinococcus multilocularis neuronal calcium sensor 0.0049 0.0102 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0015 0.0012 0.0038
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Toxoplasma gondii preprocathepsin c precursor, putative 0.0076 0.0174 0.1558
Brugia malayi hypothetical protein 0.0015 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0929 0.246 0.8112
Echinococcus granulosus cpg binding protein 0.0037 0.007 0.0229
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.004 0.0132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Trypanosoma brucei I/6 autoantigen 0.0049 0.0102 0.0858
Onchocerca volvulus 0.0031 0.0054 0.0349
Loa Loa (eye worm) hypothetical protein 0.0264 0.0679 0.2239
Loa Loa (eye worm) hypothetical protein 0.0049 0.0102 0.0334
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0102 0.0101
Schistosoma mansoni ran 0.0026 0.004 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Entamoeba histolytica calmodulin, putative 0.0049 0.0102 0.1345
Entamoeba histolytica cysteine protease, putative 0.0076 0.0174 0.2433
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0681 0.1795 0.1794
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0379 0.3508
Brugia malayi hypothetical protein 0.0015 0.0012 0.0039
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Brugia malayi Papain family cysteine protease containing protein 0.0076 0.0174 0.0575
Leishmania major centrin, putative,caltractin, putative 0.0049 0.0102 0.0858
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0115 0.038
Brugia malayi nuclear receptor NHR-88 0.0011 0.0001 0.0002
Giardia lamblia Cysteine protease 0.0076 0.0174 0.1552
Trypanosoma brucei calpain, putative 0.0105 0.0254 0.2312
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Trichomonas vaginalis myosin light chain 1, putative 0.0049 0.0102 0.0858
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0049 0.0102 0.0101
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Entamoeba histolytica cysteine protease, putative 0.0076 0.0174 0.2433
Toxoplasma gondii calmodulin CAM1 0.0049 0.0103 0.0877
Loa Loa (eye worm) acetyltransferase 0.0157 0.0393 0.1294
Leishmania major calpain family cysteine protease-like protein 0.0105 0.0254 0.2312
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0254 0.2312
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.007
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0015 0.0012 0.0011
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Toxoplasma gondii cathepsin B 0.0406 0.1058 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Echinococcus granulosus laminin 0.0015 0.0011 0.0035
Brugia malayi calpain 7 0.0351 0.091 0.3002
Mycobacterium ulcerans hydrolase 0.0026 0.0042 0.5
Onchocerca volvulus Matrix metalloproteinase homolog 0.0048 0.01 0.0654
Trypanosoma brucei cysteine peptidase C (CPC) 0.0406 0.1058 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Trypanosoma cruzi cruzipain precursor, putative 0.0358 0.093 0.3038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0351 0.091 0.2974
Echinococcus multilocularis hypothetical protein 0.0351 0.091 0.3001
Plasmodium vivax vivapain-2 0.0264 0.0679 0.7343
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0001 0.0002
Leishmania major hypothetical protein, unknown function 0.0105 0.0254 0.2312
Trypanosoma brucei calmodulin, putative 0.0049 0.0103 0.087
Trypanosoma cruzi cysteine protease, putative 0.0152 0.0379 0.1215
Schistosoma mansoni hypothetical protein 0.0031 0.0054 0.0053
Plasmodium falciparum cysteine proteinase falcipain 1 0.0152 0.0379 0.5301
Loa Loa (eye worm) hypothetical protein 0.0076 0.0176 0.058
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0047 0.0337
Echinococcus granulosus histone acetyltransferase KAT2B 0.0153 0.0381 0.1255
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0264 0.0679 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0096
Brugia malayi Cathepsin L-like precursor 0.0264 0.0679 0.224
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Plasmodium falciparum serine repeat antigen 8 0.0076 0.0174 0.2098
Brugia malayi Matrixin family protein 0.0022 0.003 0.0098
Trypanosoma brucei antigen, putative 0.0351 0.091 0.8586
Plasmodium falciparum serine repeat antigen 7 0.0076 0.0174 0.2098
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0102 0.0858
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0001 0.0001
Brugia malayi Fibulin-1 precursor 0.0015 0.0011 0.0037
Echinococcus granulosus EF hand domain containing family member A2 0.0049 0.0103 0.0338
Echinococcus multilocularis programmed cell death protein 0.0049 0.0102 0.0334
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0978 0.2591 0.259
Echinococcus granulosus dnaJ subfamily B 0.0494 0.1295 0.4268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0379 0.3508
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1143 0.3033 0.3032
Onchocerca volvulus 0.0264 0.0679 0.4461
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0015 0.0012 0.0038
Echinococcus multilocularis cathepsin L cysteine protease 0.0264 0.0679 0.2239
Schistosoma mansoni cathepsin s 0.0076 0.0176 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.0358 0.093 0.3038
Plasmodium falciparum importin beta, putative 0.0035 0.0065 0.0385
Brugia malayi hypothetical protein 0.0015 0.0012 0.0039
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0015 0.0012 0.0011
Echinococcus granulosus centrin 2 0.0049 0.0102 0.0334
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Onchocerca volvulus 0.0264 0.0679 0.4461
Trypanosoma brucei hypothetical protein 0.0105 0.0254 0.2312
Entamoeba histolytica calpain family cysteine protease, putative 0.0105 0.0254 0.3625
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0085 0.07
Echinococcus multilocularis cysteine protease 0.0264 0.0679 0.2239
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0016
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0264 0.0679 0.6377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Loa Loa (eye worm) calpain D 0.0105 0.0254 0.0836
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.0174 0.1552
Schistosoma mansoni mitochondrial solute carrier 0.0049 0.0102 0.0101
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0152 0.0379 0.1215
Echinococcus granulosus neuronal calcium sensor 0.0049 0.0102 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Brugia malayi nuclear hormone receptor 0.0011 0.0001 0.0002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0105 0.0254 0.0801
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0105 0.0254 0.0801
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0001 0.0002
Schistosoma mansoni cpg binding protein 0.0037 0.007 0.0069
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0049 0.0103 0.0301
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1143 0.3033 0.3032
Loa Loa (eye worm) hypothetical protein 0.0076 0.0174 0.0574
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Leishmania major calcineurin B subunit, putative 0.0049 0.0102 0.0858
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.004 0.0271
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0055
Entamoeba histolytica cysteine protease, putative 0.0076 0.0174 0.2433
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0076 0.0174 0.154
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0967 0.3188
Loa Loa (eye worm) hypothetical protein 0.0076 0.0174 0.0574
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0055
Entamoeba histolytica cysteine proteinase 2 0.0152 0.0379 0.5501
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Echinococcus granulosus EF HAND 1 calcium binding site 0.0049 0.0102 0.0334
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0379 0.5501
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0076 0.0174 0.2098
Trypanosoma cruzi cysteine proteinase, putative 0.0152 0.0379 0.1215
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Trypanosoma cruzi cysteine peptidase, putative 0.0358 0.093 0.3038
Giardia lamblia Cysteine protease 0.0076 0.0174 0.1552
Echinococcus multilocularis cathepsin b 0.1143 0.3033 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0076 0.0174 0.1552
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Schistosoma mansoni calmodulin related calcium binding protein 0.0049 0.0102 0.0101
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0105 0.0254 0.2312
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0085 0.1097
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0049 0.0102 0.1345
Entamoeba histolytica calcium-binding protein, putative 0.0049 0.0102 0.1345
Trypanosoma cruzi conserved protein 0.0105 0.0254 0.0801
Trypanosoma cruzi calmodulin, putative 0.0049 0.0102 0.0297
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0076 0.0174 0.0174
Echinococcus granulosus cathepsin l1 0.0264 0.0679 0.2239
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0095 0.0806
Onchocerca volvulus 0.0579 0.1522 1
Onchocerca volvulus 0.0015 0.0012 0.0074
Loa Loa (eye worm) hypothetical protein 0.0076 0.0176 0.058
Schistosoma mansoni calmodulin 0.0049 0.0102 0.0101
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0049 0.0102 0.0297
Loa Loa (eye worm) calpain family protein 1 0.0929 0.246 0.8112
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0001 0.0002
Plasmodium vivax serine-repeat antigen (SERA) 0.0076 0.0174 0.154
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma brucei Calpain-like protein 2 0.0105 0.0254 0.2312
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0015 0.0012 0.0011
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Giardia lamblia Cathepsin B precursor 0.0076 0.0174 0.1552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.0475 0.4421
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.0174 0.1552
Trichomonas vaginalis calpain, putative 0.0105 0.0254 0.2312
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Trypanosoma brucei calpain-like protein, putative 0.0351 0.091 0.8586
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0022
Leishmania major hypothetical protein, conserved 0.0105 0.0254 0.2312
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0012 0.0011
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0001 0.0001
Echinococcus multilocularis cathepsin L cysteine protease 0.0264 0.0679 0.2239
Giardia lamblia Cathepsin B precursor 0.0076 0.0174 0.1552
Echinococcus multilocularis calpain 5 0.0351 0.091 0.3001
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0102 0.0858
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0102 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Schistosoma mansoni hypothetical protein 0.0105 0.0254 0.0253
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0379 0.5501
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.004 0.0271
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.003 0.0029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0001 0.0002
Schistosoma mansoni calpain-7 (C02 family) 0.0351 0.091 0.091
Brugia malayi Protein-tyrosine phosphatase 0.0015 0.0012 0.0039
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0015 0.0012 0.0038
Giardia lamblia Hypothetical protein 0.0049 0.0103 0.087
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0001 0.0001
Plasmodium vivax unspecified product 0.0152 0.0379 0.3893
Entamoeba histolytica hypothetical protein 0.0076 0.0174 0.2433
Leishmania major phospholipase c-like protein 0.0049 0.0102 0.0858
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0049 0.0102 0.0334
Trypanosoma brucei Calpain-like protein CALP1.3 0.0105 0.0254 0.2312
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0416 0.1085 0.3578
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0035
Toxoplasma gondii EFHC1, putative 0.0049 0.0102 0.0865
Echinococcus granulosus EF hand domain containing family member A2 0.0049 0.0102 0.0334
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Schistosoma mansoni hypothetical protein 0.0049 0.0102 0.0101
Entamoeba histolytica cysteine protease, putative 0.0264 0.0679 1
Leishmania major kinesin, putative 0.0245 0.0628 0.5889
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.0174 0.1552
Giardia lamblia Hypothetical protein 0.0076 0.0174 0.1552
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0095 0.0635
Onchocerca volvulus 0.0015 0.0012 0.0074
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0213
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0012 0.0011
Schistosoma mansoni pcd6 interacting protein-related 0.0015 0.0012 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0076 0.0174 0.1552
Schistosoma mansoni Mername-AA248 (C02 family) 0.0351 0.091 0.091
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0015 0.0012 0.0038
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0065 0.0212
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Trypanosoma brucei calpain-like protein, putative 0.0351 0.091 0.8586
Loa Loa (eye worm) hypothetical protein 0.0684 0.1804 0.5947
Giardia lamblia Cathepsin B precursor 0.0406 0.1058 1
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0049 0.0102 0.0858
Leishmania major calpain protease-like protein 0.0105 0.0254 0.2312
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0076 0.0174 0.0574
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Echinococcus multilocularis laminin 0.0015 0.0011 0.0035
Plasmodium falciparum serine repeat antigen 4 0.0076 0.0174 0.2098
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0015 0.0012 0.0039
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1143 0.3033 1
Trypanosoma cruzi cysteine peptidase, putative 0.0264 0.0679 0.2209
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0065 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Trichomonas vaginalis centrin, putative 0.0049 0.0102 0.0858
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0351 0.091 0.8586
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Brugia malayi calpain D 0.0105 0.0254 0.0837
Brugia malayi Calmodulin-like protein 0.0049 0.0102 0.0335
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Echinococcus multilocularis calmodulin 0.0049 0.0102 0.0334
Giardia lamblia Cathepsin B precursor 0.0406 0.1058 1
Giardia lamblia Hypothetical protein 0.0076 0.0174 0.1552
Onchocerca volvulus 0.0015 0.0012 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Leishmania major hypothetical protein, conserved 0.0049 0.0102 0.0858
Onchocerca volvulus 0.0015 0.0012 0.0074
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0049 0.0102 0.0297
Trichomonas vaginalis hypothetical protein 0.0105 0.0254 0.2312
Onchocerca volvulus 0.0076 0.0174 0.1141
Trichomonas vaginalis calcineurin B subunit, putative 0.0049 0.0103 0.087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0001 0.0001
Brugia malayi Matrixin family protein 0.0022 0.003 0.0098
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.8586
Entamoeba histolytica hypothetical protein 0.0028 0.0047 0.0529
Trypanosoma brucei centrin, putative 0.0049 0.0102 0.0858
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.0174 0.1552
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0076 0.0174 0.154
Leishmania major i/6 autoantigen-like protein 0.0049 0.0102 0.0858
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Onchocerca volvulus 0.0015 0.0012 0.0074
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0049 0.0102 0.0297
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0049 0.0102 0.0858
Onchocerca volvulus 0.0049 0.0102 0.0664
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Trichomonas vaginalis ran, putative 0.0026 0.004 0.0271
Plasmodium vivax unspecified product 0.0076 0.0174 0.154
Trypanosoma cruzi centrin-3 0.0049 0.0102 0.0297
Leishmania major protein kinase, putative 0.0049 0.0102 0.0858
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Giardia lamblia Cathepsin L precursor 0.0076 0.0174 0.1552
Entamoeba histolytica calcium binding family protein 0.0049 0.0102 0.1345
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0015 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0076 0.0174 0.0574
Brugia malayi Matrixin family protein 0.0052 0.0112 0.0369
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Plasmodium falciparum serine repeat antigen 6 0.0076 0.0174 0.2098
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0049 0.0102 0.0297
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.8586
Plasmodium vivax unspecified product 0.0076 0.0176 0.1564
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0095 0.0806
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0076 0.0174 0.154
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0264 0.0679 0.2239
Entamoeba histolytica protein kinase, putative 0.0245 0.0628 0.9235
Trypanosoma cruzi calmodulin, putative 0.0049 0.0102 0.0297
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0044 0.0089 0.0292
Schistosoma mansoni calmodulin 0.0049 0.0102 0.0101
Schistosoma mansoni cathepsin F (C01 family) 0.0264 0.0679 0.0679
Leishmania major calmodulin, putative 0.0049 0.0102 0.0858
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0001 0.0002
Trypanosoma brucei calpain, putative 0.0105 0.0254 0.2312
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0929 0.246 0.246
Toxoplasma gondii centrin 0.0049 0.0102 0.0865
Schistosoma mansoni importin beta-1 0.0035 0.0065 0.0064
Trichomonas vaginalis calcium binding proteins, putative 0.0049 0.0102 0.0858
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0015 0.0012 0.0011
Schistosoma mansoni reticulocalbin 0.0049 0.0103 0.0102
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0012 0.0011
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.0042 0.0139
Giardia lamblia Cathepsin B precursor 0.0076 0.0174 0.1552
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0017 0.0056
Onchocerca volvulus Matrilysin homolog 0.0022 0.003 0.019
Toxoplasma gondii cathepsin CPL 0.0264 0.0679 0.638
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0152 0.0379 0.0378
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.003 0.0096
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Brugia malayi calcium-binding protein 0.0049 0.0102 0.0335
Loa Loa (eye worm) matrixin family protein 0.0052 0.0112 0.0368
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0015 0.0012 0.0038
Toxoplasma gondii hypothetical protein 0.0105 0.0254 0.2318
Leishmania major hypothetical protein, conserved 0.0049 0.0103 0.087
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0001 0.0001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0055
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0012 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0001 0.0001
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0049 0.0103 0.0102
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0076 0.0174 0.2098
Onchocerca volvulus 0.0416 0.1085 0.7132
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0015 0.0012 0.0011
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0049 0.0102 0.1345
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Leishmania major centrin, putative 0.0049 0.0102 0.0858
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Entamoeba histolytica cysteine protease, putative 0.0076 0.0174 0.2433
Leishmania major calmodulin, putative 0.0049 0.0102 0.0858
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0076 0.0174 0.154
Schistosoma mansoni egf-like domain protein 0.0013 0.0007 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0264 0.0679 1
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0046 0.0094 0.0093
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Trichomonas vaginalis calpain, putative 0.0105 0.0254 0.2312
Echinococcus granulosus calmodulin 0.0049 0.0102 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0076 0.0174 0.1552
Entamoeba histolytica cysteine protease, putative 0.0076 0.0174 0.2433
Brugia malayi programmed cell death protein 6 0.0049 0.0102 0.0335
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0001 0.0002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0115 0.038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0065 0.0506
Giardia lamblia Cathepsin B precursor 0.0406 0.1058 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0015 0.0012 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0076 0.0176 0.058
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0105 0.0254 0.2312
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0103 0.0721
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Echinococcus granulosus GPCR family 2 0.0017 0.0017 0.0055
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Echinococcus multilocularis calpain 7 (C02 family) 0.0351 0.091 0.3001
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0015 0.0012 0.0011
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0085 0.0703
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0015 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0096
Echinococcus granulosus cathepsin L 0.0152 0.0379 0.1249
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0076 0.0174 0.154
Giardia lamblia Cathepsin L-like protease 0.0076 0.0174 0.1552
Onchocerca volvulus Cathepsin L homolog 0.0076 0.0174 0.1141
Onchocerca volvulus 0.0015 0.0012 0.0074
Loa Loa (eye worm) hypothetical protein 0.0188 0.0475 0.1564
Onchocerca volvulus 0.0015 0.0012 0.0074
Loa Loa (eye worm) AStacin protease 0.0029 0.0048 0.0157
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.004 0.0094
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Plasmodium falciparum serine repeat antigen 3 0.0076 0.0174 0.2098
Trypanosoma brucei kinesin, putative 0.0245 0.0628 0.5889
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0105 0.0254 0.2312
Onchocerca volvulus 0.0049 0.0103 0.0672
Onchocerca volvulus 0.0015 0.0012 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0076 0.0174 0.1552
Giardia lamblia Cathepsin B precursor 0.0076 0.0174 0.1552
Schistosoma mansoni ef hand domain family member A2 0.0049 0.0102 0.0101
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Onchocerca volvulus Cathepsin L homolog 0.0264 0.0679 0.4461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0015 0.0012 0.0011
Brugia malayi EF hand family protein 0.0049 0.0102 0.0335
Leishmania major cathepsin L-like protease 0.0264 0.0679 0.6377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Plasmodium falciparum cysteine proteinase falcipain 3 0.0264 0.0679 1
Echinococcus multilocularis cathepsin L 0.0152 0.0379 0.1249
Echinococcus multilocularis cathepsin L 0.0076 0.0174 0.0574
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0015 0.0012 0.0038
Echinococcus granulosus cathepsin l cysteine peptidase 0.0264 0.0679 0.2239
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0055
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0105 0.0254 0.0801
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Plasmodium vivax serine-repeat antigen (SERA) 0.0076 0.0174 0.154
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0016
Brugia malayi Papain family cysteine protease containing protein 0.0076 0.0174 0.0575
Brugia malayi acetyltransferase, GNAT family protein 0.0157 0.0393 0.1295
Giardia lamblia Cathepsin L precursor 0.0076 0.0174 0.1552
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0872 0.2307 0.7608
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0406 0.1058 1
Trypanosoma brucei protein I/6 0.0049 0.0102 0.0858
Entamoeba histolytica calmodulin, putative 0.0049 0.0102 0.1345
Onchocerca volvulus 4.1 G protein, putative homolog 0.0015 0.0012 0.0074
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Schistosoma mansoni calpain-7 (C02 family) 0.0351 0.091 0.091
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0076 0.0174 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0001 0.0002
Echinococcus granulosus calpain 7 C02 family 0.0351 0.091 0.3001
Echinococcus granulosus cathepsin b 0.1143 0.3033 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0152 0.0379 0.0378
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0264 0.0679 0.2239
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0105 0.0254 0.2318
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.004 0.0133
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0102 0.0858
Leishmania major cathepsin L-like protease 0.0358 0.093 0.8771
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0076 0.0174 0.0575
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0001 0.0001
Trypanosoma cruzi I/6 autoantigen, putative 0.0049 0.0102 0.0297
Giardia lamblia Cathepsin L precursor 0.0076 0.0174 0.1552
Schistosoma mansoni hypothetical protein 0.0049 0.0102 0.0101
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0076 0.0174 0.0174
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0079 0.0182 0.06
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Echinococcus multilocularis cysteine protease 0.0264 0.0679 0.2239
Brugia malayi EF hand family protein 0.0049 0.0103 0.0339
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0076 0.0174 0.1552
Giardia lamblia Cathepsin L-like protease 0.0076 0.0174 0.1552
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0016
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0095 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0174 0.1552
Echinococcus granulosus calcium uptake protein 1 0.0049 0.0103 0.0338
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0015 0.0012 0.0038
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0012 0.0011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0351 0.091 0.2974
Leishmania major calmodulin-like protein 0.0049 0.0102 0.0858
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Trypanosoma cruzi centrin, putative 0.0049 0.0102 0.0297
Echinococcus multilocularis hypothetical protein 0.0015 0.0012 0.0038
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0158 0.1402
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Leishmania major importin beta-1 subunit, putative 0.0028 0.0047 0.0337
Brugia malayi Papain family cysteine protease containing protein 0.0264 0.0679 0.224
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0015 0.0012 0.0011
Schistosoma mansoni calpain-2 (C02 family) 0.0105 0.0254 0.0253
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Schistosoma mansoni cathepsin S (C01 family) 0.0076 0.0174 0.0174
Echinococcus multilocularis calbindin 32 0.0049 0.0103 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Onchocerca volvulus 0.0015 0.0012 0.0074
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0264 0.0679 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0264 0.0679 0.2239
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0105 0.0254 0.2312
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0076 0.0174 0.0574
Trypanosoma brucei centrin-3 0.0049 0.0102 0.0858
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0076 0.0174 0.0574
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0049 0.0102 0.0334
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Echinococcus granulosus calumenin 0.0049 0.0103 0.0338
Loa Loa (eye worm) cysteine protease 0.0264 0.0679 0.2239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0001 0.0001
Loa Loa (eye worm) calpain 5 0.0245 0.0628 0.207
Brugia malayi Papain family cysteine protease containing protein 0.0076 0.0174 0.0575
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0001 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0169 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.0475 0.4421
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0076 0.0174 0.0574
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0001 0.0002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.2974
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0076 0.0174 0.0174
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0362 0.0942 0.0941
Toxoplasma gondii troponin c, isotype gamma, putative 0.0049 0.0102 0.0865
Trypanosoma cruzi caltractin, putative 0.0049 0.0102 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0076 0.0174 0.1552
Trypanosoma brucei centrin, putative 0.0049 0.0102 0.0858
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Loa Loa (eye worm) ctsf protein 0.0264 0.0679 0.2239
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0012 0.0038
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0076 0.0174 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0379 0.3508
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0152 0.0379 0.0378
Giardia lamblia Cathepsin B precursor 0.0076 0.0174 0.1552
Loa Loa (eye worm) calpain 0.0351 0.091 0.3001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Plasmodium vivax vivapain-1 0.0152 0.0379 0.3893
Loa Loa (eye worm) programmed cell death protein 6 0.0049 0.0103 0.0338
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0001 0.0001
Plasmodium vivax importin-beta 2, putative 0.0035 0.0065 0.0283
Plasmodium vivax vivapain-3 0.0152 0.0379 0.3893
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0076 0.0174 0.0174
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0579 0.1522 0.5016
Leishmania major cathepsin L-like protease 0.0264 0.0679 0.6377
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0105 0.0254 0.0801
Loa Loa (eye worm) hypothetical protein 0.0188 0.0475 0.1564
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.8586
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0406 0.1058 1
Trypanosoma cruzi calmodulin, putative 0.0049 0.0102 0.0297
Plasmodium falciparum centrin-1 0.0049 0.0102 0.0962
Schistosoma mansoni hypothetical protein 0.0366 0.0952 0.0951
Brugia malayi Matrixin family protein 0.0022 0.003 0.0098
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Echinococcus granulosus cathepsin l1 0.0188 0.0475 0.1564
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0138
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0001 0.0001
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0079 0.0182 0.06
Onchocerca volvulus 0.0049 0.0102 0.0664
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0264 0.0679 0.6377
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0017 0.0055
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0076 0.0174 0.1552
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0015 0.0012 0.0038
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0176 0.0544
Leishmania major calmodulin-like protein 0.0049 0.0102 0.0858
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0015 0.0012 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0049 0.0102 0.0858
Echinococcus multilocularis calumenin 0.0049 0.0103 0.0338
Trypanosoma brucei cysteine peptidase, putative 0.0105 0.0254 0.2312
Brugia malayi cathepsin L-like precursor 0.0188 0.0475 0.1565
Toxoplasma gondii cathepsin CPC2 0.0076 0.0174 0.1558
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0351 0.091 0.2974
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0406 0.1058 0.1058
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Brugia malayi steroid hormone receptor 0.0011 0.0001 0.0002
Leishmania major cathepsin L-like protease 0.0358 0.093 0.8771
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0076 0.0174 0.154
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0102 0.0858
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.004 0.0279
Echinococcus multilocularis geminin 0.0366 0.0952 0.3139
Trypanosoma brucei calmodulin, putative 0.0049 0.0102 0.0858
Onchocerca volvulus Arrow homolog 0.0013 0.0007 0.0042
Loa Loa (eye worm) protein tyrosine phosphatase 0.0015 0.0012 0.0038
Echinococcus multilocularis calmodulin 0.0049 0.0102 0.0334
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0046 0.0094 0.0309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Schistosoma mansoni rab 0.0049 0.0102 0.0101
Trichomonas vaginalis calcineurin B subunit, putative 0.0049 0.0102 0.0858
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0362 0.0942 0.3105
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0001 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0015 0.0012 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Echinococcus granulosus calbindin 32 0.0049 0.0103 0.0338
Entamoeba histolytica grainin, putative 0.0049 0.0103 0.1364
Brugia malayi calpain family protein 1 0.0929 0.246 0.8113
Trypanosoma cruzi cysteine proteinase, putative 0.0152 0.0379 0.1215
Onchocerca volvulus 0.0015 0.0012 0.0074
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1143 0.3033 0.3032
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0049 0.0102 0.0858
Trichomonas vaginalis calmodulin-2, putative 0.0049 0.0102 0.0858
Toxoplasma gondii EF hand domain-containing protein 0.0049 0.0102 0.0865
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0076 0.0174 0.2433
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0012 0.0011
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0049 0.0102 0.0706
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0362 0.0942 0.3105
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Plasmodium falciparum calpain 0.0105 0.0254 0.3343
Brugia malayi Cathepsin L-like precursor 0.0264 0.0679 0.224
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.2974
Onchocerca volvulus 0.0015 0.0012 0.0074
Leishmania major cathepsin L-like protease 0.0264 0.0679 0.6377
Trypanosoma cruzi centrin, putative 0.0049 0.0102 0.0297
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.007 0.023
Schistosoma mansoni centrin 0.0049 0.0102 0.0101
Echinococcus multilocularis calpain 0.0351 0.091 0.3001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Onchocerca volvulus 0.0015 0.0012 0.0074
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0001 0.0001
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0978 0.2591 0.259
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0001 0.0002
Onchocerca volvulus 0.0188 0.0475 0.3115
Brugia malayi Papain family cysteine protease containing protein 0.0152 0.0379 0.125
Loa Loa (eye worm) hypothetical protein 0.0076 0.0176 0.058
Onchocerca volvulus 0.0264 0.0679 0.4461
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Onchocerca volvulus 0.0015 0.0012 0.0074
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0264 0.0679 0.2239
Echinococcus granulosus importin subunit beta 1 0.0035 0.0065 0.0213
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0105 0.0254 0.0801
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0001 0.0001
Trypanosoma cruzi major cysteine proteinase, putative 0.0076 0.0174 0.0537
Trypanosoma brucei calpain-like protein, putative 0.0351 0.091 0.8586
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.0174 0.1552
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0076 0.0174 0.0174
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Trypanosoma brucei Component of motile flagella 41 0.0049 0.0102 0.0858
Schistosoma mansoni hypothetical protein 0.0366 0.0952 0.0951
Toxoplasma gondii centrin, putative 0.0049 0.0102 0.0865
Trypanosoma brucei caltractin, putative 0.0049 0.0102 0.0858
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0157 0.0393 0.1294
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.2974
Giardia lamblia Cathepsin L precursor 0.0076 0.0174 0.1552
Brugia malayi CXXC zinc finger family protein 0.0035 0.0065 0.0213
Trypanosoma cruzi major cysteine proteinase, putative 0.0169 0.0425 0.1367
Schistosoma mansoni calpain (C02 family) 0.0351 0.091 0.091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.2974
Schistosoma mansoni cpg binding protein 0.0037 0.007 0.0069
Echinococcus granulosus calpain A 0.0978 0.2592 0.8545
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Echinococcus multilocularis neurocalcin 0.0049 0.0102 0.0334
Echinococcus granulosus snurportin 1 0.0372 0.0967 0.3188
Onchocerca volvulus 0.0015 0.0012 0.0074
Echinococcus granulosus programmed cell death protein 0.0049 0.0102 0.0334
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Brugia malayi Matrixin family protein 0.0022 0.003 0.0098
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0076 0.0174 0.154
Toxoplasma gondii cathepsin CPC1 0.0076 0.0174 0.1558
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.004 0.0132
Brugia malayi Cathepsin L-like precursor 0.0264 0.0679 0.224
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0102 0.0858
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0016
Brugia malayi Calcium binding EGF domain containing protein 0.0015 0.0011 0.0037
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Echinococcus granulosus cysteine protease 0.0152 0.0379 0.1249
Leishmania major GTP-binding protein, putative 0.0026 0.004 0.0271
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Trypanosoma cruzi cysteine peptidase, putative 0.0152 0.0379 0.1215
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0095 0.0314
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0105 0.0254 0.2312
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0013 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0188 0.0475 0.1564
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Echinococcus multilocularis calpain A 0.0978 0.2592 0.8545
Giardia lamblia Cathepsin L precursor 0.0076 0.0174 0.1552
Onchocerca volvulus Cathepsin F homolog 0.0264 0.0679 0.4461
Trypanosoma cruzi cysteine peptidase, putative 0.0358 0.093 0.3038
Trichomonas vaginalis calmodulin, putative 0.0049 0.0103 0.087
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0015 0.0012 0.0038
Onchocerca volvulus 0.0264 0.0679 0.4461
Brugia malayi hypothetical protein 0.0015 0.0012 0.0039
Brugia malayi ecdysteroid receptor 0.0011 0.0001 0.0002
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0015 0.0012 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0102 0.0858
Entamoeba histolytica cysteine proteinase, putative 0.0188 0.0475 0.6932
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0351 0.091 0.8586
Plasmodium vivax calpain, putative 0.0351 0.091 1
Leishmania major cathepsin L-like protease 0.0264 0.0679 0.6377
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0362 0.0942 0.3106
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0351 0.091 0.2974
Plasmodium falciparum serine repeat antigen 9 0.0076 0.0174 0.2098
Echinococcus multilocularis snurportin 1 0.0372 0.0967 0.3188
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0076 0.0174 0.0174
Brugia malayi cathepsin B-like cysteine proteinase 0.1143 0.3033 1
Loa Loa (eye worm) EF hand family protein 0.0049 0.0102 0.0334
Loa Loa (eye worm) hypothetical protein 0.0076 0.0174 0.0574
Onchocerca volvulus 0.0416 0.1085 0.7132
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Loa Loa (eye worm) hypothetical protein 0.0824 0.2178 0.7182
Brugia malayi Cathepsin L-like precursor 0.0188 0.0475 0.1565
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0174 0.1552
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.004 0.0132
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0157 0.0393 0.0392
Brugia malayi Cathepsin L-like precursor 0.0264 0.0679 0.224
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0978 0.2591 0.8541
Brugia malayi calpain family protein 1 0.0929 0.246 0.8113
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0105 0.0254 0.0801
Brugia malayi fibroinase precursor 0.0076 0.0174 0.0575
Schistosoma mansoni cpg binding protein 0.0035 0.0065 0.0064
Loa Loa (eye worm) cathepsin B 0.0406 0.1058 0.3489
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Schistosoma mansoni cathepsin F (C01 family) 0.0264 0.0679 0.0679
Onchocerca volvulus 0.0022 0.003 0.019
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.0042 0.5
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0105 0.0254 0.0801
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0015 0.0011 0.0035
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Trypanosoma brucei mitochondrial calcium uptake 1 0.0049 0.0102 0.0858
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0049 0.0102 0.0297
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1143 0.3033 0.3032
Brugia malayi cathepsin L precursor 0.0076 0.0174 0.0575
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0379 0.5501
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0015 0.0012 0.0038
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.0801
Trichomonas vaginalis centrin, putative 0.0049 0.0102 0.0858
Loa Loa (eye worm) hypothetical protein 0.0037 0.007 0.0229
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0105 0.0254 0.0801
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0351 0.091 0.2974
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0047 0.0337
Brugia malayi Cathepsin L-like precursor 0.0264 0.0679 0.224
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0076 0.0174 0.1552
Leishmania major cathepsin L-like protease 0.0358 0.093 0.8771
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Plasmodium vivax centrin-1, putative 0.0049 0.0102 0.0706
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0416 0.1085 0.3579
Brugia malayi calpain 5 0.0105 0.0254 0.0837
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0115 0.0379
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Onchocerca volvulus 0.0015 0.0012 0.0074
Plasmodium vivax vivapain-2 0.0264 0.0679 0.7343
Plasmodium falciparum serine repeat antigen 1 0.0076 0.0174 0.2098
Toxoplasma gondii calcium-dependent protein kinase 0.0049 0.0103 0.0877
Leishmania major cysteine peptidase A (CPA) 0.0264 0.0679 0.6377
Echinococcus multilocularis fibrillin 1 0.0015 0.0011 0.0035
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0076 0.0174 0.2098
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0001 0.0002
Echinococcus granulosus calpain 0.0351 0.091 0.3001
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0015 0.0012 0.0038
Brugia malayi Papain family cysteine protease containing protein 0.0152 0.0379 0.125
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0001 0.0001
Onchocerca volvulus Matrilysin homolog 0.0048 0.01 0.0654
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.0174 0.1552
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0065 0.0506
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0001 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.1295 0.4268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.0174 0.1552
Echinococcus multilocularis GPCR, family 2 0.0017 0.0017 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0001 0.0002
Echinococcus multilocularis calpain family protein 1, d 0.0684 0.1804 0.5947
Entamoeba histolytica cysteine proteinase, putative 0.0264 0.0679 1
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0176 0.0544
Schistosoma mansoni cathepsin F (C01 family) 0.0188 0.0475 0.0474
Brugia malayi cathepsin Z-like cysteine proteinase 0.0076 0.0174 0.0575
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0096
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0012 0.0011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Leishmania major cathepsin L-like protease 0.0264 0.0679 0.6377
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0001 0.0001
Brugia malayi Cathepsin L-like cysteine proteinase 0.0188 0.0475 0.1565
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Brugia malayi Protein-tyrosine phosphatase 0.0015 0.0012 0.0039
Loa Loa (eye worm) fibroinase 0.0264 0.0679 0.2239
Echinococcus granulosus protein tyrosine phosphatase n9 0.0015 0.0012 0.0038
Giardia lamblia Cysteine protease 0.0076 0.0174 0.1552
Echinococcus multilocularis calcium uptake protein 1 0.0049 0.0103 0.0338
Echinococcus granulosus neurocalcin 0.0049 0.0102 0.0334
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0076 0.0174 0.0174
Entamoeba histolytica cysteine proteinase 1, putative 0.0152 0.0379 0.5501
Echinococcus granulosus cathepsin L 0.0076 0.0174 0.0574
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.0174 0.1552
Echinococcus multilocularis EF hand domain containing family member A2 0.0049 0.0103 0.0338
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Echinococcus granulosus cathepsin L cysteine proteinase 0.0264 0.0679 0.2239
Entamoeba histolytica cysteine protease, putative 0.0152 0.0379 0.5501
Echinococcus multilocularis Tolloid protein 1 0.0046 0.0094 0.0309
Entamoeba histolytica calpain large subunit domain III containing protein 0.0245 0.0628 0.9235
Echinococcus granulosus geminin 0.0366 0.0952 0.3139
Entamoeba histolytica Ran family GTPase 0.0026 0.004 0.0424
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0049 0.0102 0.0334
Onchocerca volvulus 0.0015 0.0012 0.0074
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0076 0.0174 0.154
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Echinococcus granulosus Tolloid protein 1 0.0046 0.0094 0.0309
Brugia malayi cathepsin F-like cysteine proteinase 0.0076 0.0174 0.0575
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0105 0.0254 0.2312
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0012 0.0038
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0362 0.0942 0.3105
Schistosoma mansoni ran 0.0026 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0494 0.1295 0.1294
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Onchocerca volvulus 0.0015 0.0012 0.0074
Plasmodium falciparum serine repeat antigen 2 0.0076 0.0174 0.2098
Trypanosoma brucei calpain-like protein, putative 0.0351 0.091 0.8586
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Giardia lamblia Cathepsin L precursor 0.0076 0.0174 0.1552
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0379 0.5501
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0103 0.1364
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0105 0.0254 0.0801
Loa Loa (eye worm) hypothetical protein 0.0049 0.0102 0.0334
Echinococcus granulosus calpain 5 0.0351 0.091 0.3001
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0076 0.0174 0.1552
Echinococcus multilocularis 0.0015 0.0012 0.0038
Echinococcus multilocularis centrin 2 0.0049 0.0102 0.0334
Loa Loa (eye worm) hypothetical protein 0.0105 0.0254 0.0836
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0095 0.0798
Schistosoma mansoni hypothetical protein 0.0037 0.007 0.0069
Echinococcus multilocularis cathepsin b 0.1143 0.3033 1
Brugia malayi Protein-tyrosine phosphatase 1 0.0015 0.0012 0.0039
Giardia lamblia Encystation-specific protease 0.0076 0.0174 0.1552
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0105 0.0254 0.2312
Loa Loa (eye worm) hypothetical protein 0.0054 0.0115 0.0379
Trypanosoma cruzi kinesin, putative 0.0245 0.0628 0.204
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Trypanosoma brucei Calpain-like protein 1.2 0.0105 0.0254 0.2312
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0102 0.0101
Trichomonas vaginalis calpain, putative 0.0105 0.0254 0.2312
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0406 0.1058 0.3464
Brugia malayi Importin beta-1 subunit 0.0035 0.0065 0.0214
Onchocerca volvulus Cathepsin L homolog 0.0264 0.0679 0.4461
Brugia malayi cathepsin F-like cysteine proteinase 0.0076 0.0176 0.0581
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0358 0.093 0.8771
Brugia malayi cathepsin L-like cysteine proteinase 0.0076 0.0174 0.0575
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0047 0.0337
Brugia malayi calpain 5 0.0245 0.0628 0.2071
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0105 0.0254 0.0801
Giardia lamblia Cysteine protease 0.0076 0.0174 0.1552
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0012 0.0038
Schistosoma mansoni calpain C (C02 family) 0.0351 0.091 0.091
Trichomonas vaginalis calmodulin, putative 0.0049 0.0102 0.0858
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Loa Loa (eye worm) matrixin family protein 0.0048 0.01 0.0329
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0022
Echinococcus multilocularis EF hand domain containing family member A2 0.0049 0.0102 0.0334
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0001 0.0001
Trypanosoma cruzi kinesin, putative 0.0245 0.0628 0.204
Echinococcus multilocularis programmed cell death protein 0.0049 0.0102 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0065 0.0514
Brugia malayi Cathepsin L-like precursor 0.0264 0.0679 0.224
Onchocerca volvulus 0.0015 0.0012 0.0074
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0105 0.0254 0.2312
Onchocerca volvulus 0.0015 0.0012 0.0074
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0012 0.0038
Onchocerca volvulus 0.0015 0.0012 0.0074
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0281 0.0725 0.2361
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0351 0.091 0.2974
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0001 0.0001
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0978 0.2591 0.8541
Entamoeba histolytica cysteine protease, putative 0.0076 0.0174 0.2433
Onchocerca volvulus 0.0264 0.0679 0.4461
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0012 0.0039
Brugia malayi cathepsin Z-like cysteine proteinase 0.0076 0.0174 0.0575
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0102 0.0858
Schistosoma mansoni cathepsin C 0.0076 0.0174 0.0174
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0076 0.0174 0.1552
Schistosoma mansoni centrin-related 0.0049 0.0102 0.0101
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.004 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0264 0.0679 0.6377
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0076 0.0174 0.1552
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0106 0.0255 0.2326
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0012 0.0011
Plasmodium falciparum serine repeat antigen 5 0.0076 0.0174 0.2098
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0076 0.0174 0.2433
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0076 0.0174 0.154
Trypanosoma brucei Calpain-like protein 1.1 0.0105 0.0254 0.2312
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.0174 0.1552
Leishmania major programmed cell death 6 protein-like protein 0.0049 0.0102 0.0858
Schistosoma mansoni hypothetical protein 0.0372 0.0967 0.0967
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0076 0.0176 0.0581
Schistosoma mansoni cathepsin B (C01 family) 0.0076 0.0174 0.0174
Loa Loa (eye worm) calpain family protein 1 0.0684 0.1804 0.5947
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0055
Onchocerca volvulus 0.0015 0.0012 0.0074
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0102 0.0101
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0076 0.0174 0.0574
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0001 0.0002
Brugia malayi Cathepsin L-like precursor 0.0188 0.0475 0.1565
Echinococcus granulosus calpain A 0.0351 0.091 0.3001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0038
Leishmania major centrin, putative 0.0049 0.0102 0.0858
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0076 0.0174 0.1552
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Hemopexin family protein 0.0031 0.0054 0.0178
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0017 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0264 0.0679 0.6377
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0012 0.0038

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.8356 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 5.6234 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 23.7781 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 75.193 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 95.2834 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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