Detailed information for compound 138366

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 343.46 | Formula: C21H29NO3
  • H donors: 2 H acceptors: 2 LogP: 3.29 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC1[C@@H](O)CC2C1(C)CCC1C2CCc2c1ccc(c2)OC(=O)C
  • InChi: 1S/C21H29NO3/c1-12(23)25-14-5-7-15-13(10-14)4-6-17-16(15)8-9-21(2)18(17)11-19(24)20(21)22-3/h5,7,10,16-20,22,24H,4,6,8-9,11H2,1-3H3/t16?,17?,18?,19-,20?,21?/m1/s1
  • InChiKey: ONRLQQZRVWGJEO-MTIYKSONSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis activated cdc42 kinase 1 0.0018 0.0013 0.0013
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.0147 1
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0021 0.1288
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine protein kinase Src64B 0.004 0.0047 0.0047
Loa Loa (eye worm) protein-tyrosine kinase 0.0011 0.0003 0.0027
Schistosoma mansoni tyrosine kinase 0.004 0.0047 0.0364
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0039 0.0308
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.009 0.0123 0.0116
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0061 0.4057
Echinococcus multilocularis intersectin 2 0.0011 0.0003 0.0003
Onchocerca volvulus Netrin receptor homolog 0.0019 0.0015 0.0212
Schistosoma mansoni dreadlocks/dock 0.0011 0.0003 0.0023
Onchocerca volvulus 0.0011 0.0003 0.0037
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0018 0.0013 0.0115
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0001 0.0007
Schistosoma mansoni nck2/grb4 0.0023 0.002 0.0158
Onchocerca volvulus 0.0012 0.0004 0.0041
Echinococcus multilocularis epidermal growth factor receptor 0.0018 0.0013 0.0013
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0007 0.0273
Echinococcus multilocularis nostrin 0.0011 0.0003 0.0003
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0011 0.0003 0.0003
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0013 0.0674
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Loa Loa (eye worm) TK/ACK protein kinase 0.0018 0.0013 0.0115
Brugia malayi 6-phosphofructokinase 0.0106 0.0147 0.1346
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0267
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0016 0.0016
Entamoeba histolytica serine/threonine kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0018 0.0013 0.0013
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0013 0.0428
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.003 0.2231
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0038 0.0345
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0206 0.0206
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0103 0.0142 0.0142
Onchocerca volvulus 0.0029 0.003 0.043
Schistosoma mansoni shc transforming protein 0.0011 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Plasmodium vivax tyrosine kinase-like protein, putative 0.0018 0.0013 0.0563
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0001 0.0001
Echinococcus multilocularis heat shock protein 70 0.0018 0.0013 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0051 0.3326
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.1848
Brugia malayi hypothetical protein 0.005 0.0061 0.0562
Loa Loa (eye worm) thyroid receptor interactor 0.0011 0.0003 0.0027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Echinococcus multilocularis c src tyrosine kinase 0.004 0.0047 0.0047
Entamoeba histolytica receptor protein kinase, putative 0.0018 0.0013 0.0671
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0013 0.0674
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0147 0.1147
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0028 0.0029 0.0224
Schistosoma mansoni apoptosis stimulating of P53 0.0011 0.0003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0657
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0696
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Echinococcus multilocularis tyrosine kinase 0.0018 0.0013 0.0013
Brugia malayi SH2 domain containing protein 0.0011 0.0003 0.0031
Brugia malayi STAT protein, DNA binding domain containing protein 0.0011 0.0003 0.0031
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0018 0.0013 0.0013
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.003 0.2231
Echinococcus granulosus activated cdc42 kinase 1 0.0018 0.0013 0.0013
Echinococcus multilocularis musashi 0.0053 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Toxoplasma gondii STE kinase 0.0018 0.0013 0.0425
Trichomonas vaginalis protein kinase atn1, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis titin 0.0019 0.0015 0.0015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0047 0.0047
Brugia malayi glutathione reductase 0.004 0.0046 0.0422
Echinococcus multilocularis transfer RNA-Phe 0.0019 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase otk 0.0028 0.0029 0.0029
Echinococcus granulosus hypothetical protein 0.0011 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0035 0.0039 0.2533
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0046 0.3852
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0015 0.0139
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Echinococcus granulosus suppressor of cytokine signaling 7 0.0011 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus intersectin 2 0.0011 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0047 0.0047
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0016 0.0888
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni hypothetical protein 0.0034 0.0038 0.0294
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0019 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Schistosoma mansoni protein tyrosine kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0011 0.0003 0.0031
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0081 0.0108 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Loa Loa (eye worm) SH2 domain-containing protein 0.0011 0.0003 0.0031
Loa Loa (eye worm) p53BP2 0.0011 0.0003 0.0027
Echinococcus multilocularis integrin linked protein kinase 0.0018 0.0013 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0016 0.0142
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0013 0.0567
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0018 0.0013 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.1848
Loa Loa (eye worm) RGC/RGC protein kinase 0.0018 0.0013 0.0115
Echinococcus multilocularis raf serine:threonine protein kinase 0.0018 0.0013 0.0013
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0018 0.0013 0.0013
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0011 0.0003 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni titin 0.0019 0.0015 0.0118
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Entamoeba histolytica serine/threonine kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis protein kinase 0.0018 0.0013 0.0013
Plasmodium falciparum importin beta, putative 0.0029 0.003 0.225
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0025 0.0025
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0023 0.002 0.0185
Brugia malayi SH2 domain containing protein 0.0011 0.0003 0.0031
Schistosoma mansoni coup transcription factor 0.001 0.0001 0.0007
Echinococcus granulosus raf serine:threonine protein kinase 0.0018 0.0013 0.0013
Brugia malayi protein-tyrosine kinase 0.0029 0.003 0.0273
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0028 0.0029 0.0029
Schistosoma mansoni SH2A 0.0011 0.0003 0.0026
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0061 0.536
Echinococcus multilocularis protein KINase family member (kin 25) 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.027
Schistosoma mansoni myosin-binding protein-related 0.0019 0.0015 0.0118
Schistosoma mansoni vav2 0.0011 0.0003 0.0026
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.003 0.1683
Onchocerca volvulus 0.0019 0.0016 0.0217
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0011 0.0003 0.0027
Loa Loa (eye worm) phosphofructokinase 0.0106 0.0147 0.1346
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.0118
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Schistosoma mansoni tyrosine protein kinase 0.0018 0.0013 0.0098
Echinococcus multilocularis natriuretic peptide receptor 1 0.0018 0.0013 0.0013
Echinococcus granulosus tyrosine kinase 0.0018 0.0013 0.0013
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0081 0.0108 1
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0013 0.072
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Schistosoma mansoni nephrin related 0.0019 0.0015 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0018 0.1061
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0029 0.023
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine protein kinase Src42A 0.0011 0.0003 0.0003
Schistosoma mansoni ephrin receptor 0.0018 0.0013 0.0098
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0007 0.0273
Brugia malayi Prion-like- 0.0028 0.0029 0.0266
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0018 0.0013 0.0115
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0003 0.0003
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0029 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0001 0.0008
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.0208 0.191
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Echinococcus multilocularis signal transduction protein lnk realted 0.0011 0.0003 0.0003
Echinococcus multilocularis twitchin 0.002 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Schistosoma mansoni suppressor of cytokine signaling 0.0011 0.0003 0.0026
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.002 0.0016 0.0145
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0081 0.0108 0.7259
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0018 0.0013 0.0115
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0018 0.0167
Echinococcus multilocularis tyrosine protein kinase HCK 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Loa Loa (eye worm) projectin 0.0019 0.0015 0.0139
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.1848
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0018 0.0013 0.0013
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0015 0.0139
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0025 0.0025
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Fibronectin type III domain containing protein 0.0028 0.0029 0.0263
Echinococcus multilocularis tyrosine protein kinase Src64B 0.004 0.0047 0.0047
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0018 0.0013 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0013 0.0115
Brugia malayi Protein kinase domain containing protein 0.0731 0.1091 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0007 0.0273
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Schistosoma mansoni importin beta-1 0.0029 0.003 0.0232
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0018 0.0013 0.0115
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.0047 0.0047
Onchocerca volvulus Tyrosine kinase homolog 0.0455 0.0674 1
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0011 0.0003 0.0031
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0028 0.0029 0.0418
Brugia malayi protein-tyrosine kinase 0.0011 0.0003 0.0027
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0046 0.0422
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0016 0.09
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0018 0.0842
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Brugia malayi Raf kinase 0.0018 0.0013 0.0115
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0176 0.0253 0.0253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0001 0.0008
Schistosoma mansoni cpg binding protein 0.0032 0.0035 0.0273
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Echinococcus granulosus retinal guanylyl cyclase 2 0.0018 0.0013 0.0013
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0039 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0147 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0016 0.09
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0035 0.0039 0.2533
Echinococcus granulosus lachesin 0.0028 0.0029 0.0029
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0029 0.003 0.0273
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0018 0.0013 0.0115
Schistosoma mansoni nuclear hormone receptor 0.001 0.0001 0.0007
Brugia malayi protein unc-22 0.002 0.0016 0.0145
Echinococcus multilocularis endophilin A3 0.0011 0.0003 0.0003
Echinococcus granulosus c src tyrosine kinase 0.004 0.0047 0.0047
Onchocerca volvulus 0.0019 0.0015 0.0212
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0018 0.0018
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0007 0.0007
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.0147 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.0147 0.0426
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0142 0.1106
Echinococcus granulosus geminin 0.0856 0.128 0.128
Onchocerca volvulus Putative titin 0.0019 0.0015 0.0212
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0147 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0206 0.161
Plasmodium falciparum protein kinase, putative 0.0018 0.0013 0.0563
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0018 0.0013 0.0013
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0003 0.0003
Echinococcus granulosus titin 0.0019 0.0015 0.0015
Schistosoma mansoni thyroid hormone receptor 0.001 0.0001 0.0007
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0019 0.0015 0.0212
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0011 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0696
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0015 0.0139
Schistosoma mansoni hypothetical protein 0.0856 0.128 1
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0016 0.0888
Brugia malayi ephrin receptor 1 precursor 0.0018 0.0013 0.0115
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0007 0.0273
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.0016 0.0145
Brugia malayi Probable ClpP-like protease 0.0081 0.0108 0.0994
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Echinococcus granulosus snurportin 1 0.0308 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Loa Loa (eye worm) one IG domain family member 0.0019 0.0015 0.0139
Leishmania major protein kinase, putative 0.0018 0.0013 0.072
Echinococcus granulosus tyrosine protein kinase 0.0018 0.0013 0.0013
Onchocerca volvulus 0.0029 0.003 0.043
Brugia malayi phosphofructokinase 0.0106 0.0147 0.1346
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0147 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0016 0.0009
Plasmodium vivax tyrosine kinase-like protein, putative 0.0018 0.0013 0.0563
Brugia malayi Importin beta-1 subunit 0.0029 0.003 0.0272
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.026 0.385
Mycobacterium tuberculosis Probable oxidoreductase 0.01 0.0138 0.0131
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.009 0.0123 0.0116
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0016 0.2341
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0011 0.0003 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0108 0.0149 0.1365
Schistosoma mansoni sorting nexin 0.0011 0.0003 0.0023
Echinococcus multilocularis peroxidasin 0.0029 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis SH2 motif 0.0011 0.0003 0.0003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0016 0.0009
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Schistosoma mansoni peroxidasin 0.0009 0 0.0003
Loa Loa (eye worm) glutathione reductase 0.004 0.0046 0.0422
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0671
Brugia malayi SH2 domain containing protein 0.0011 0.0003 0.0031
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.004 0.0047 0.0047
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0032 0.0297
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Schistosoma mansoni growth factor receptor-bound protein 0.0023 0.002 0.0158
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0266
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Echinococcus granulosus roundabout 2 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0628 0.0935 0.8573
Entamoeba histolytica tyrosin kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Brugia malayi Myb-like DNA-binding domain containing protein 0.0019 0.0015 0.0139
Schistosoma mansoni serine/threonine RGC 0.0018 0.0013 0.0098
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0013 0.0116
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0011 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0018 0.0018
Entamoeba histolytica tyrosin kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni hypothetical protein 0.0856 0.128 1
Echinococcus multilocularis GPCR, family 2 0.0034 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0142 0.1106
Echinococcus multilocularis N chimaerin 0.0011 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Echinococcus multilocularis SH2 motif 0.0011 0.0003 0.0003
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0007 0.0273
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.003 0.1862
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis tyrosine protein kinase shark 0.0029 0.003 0.003
Onchocerca volvulus 0.0011 0.0003 0.0037
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.187 0.2813 1
Schistosoma mansoni formin binding protein and related proteins 0.0011 0.0003 0.0023
Entamoeba histolytica Ran family GTPase 0.0021 0.0018 0.1061
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.003 0.1683
Echinococcus granulosus nephrin 0.0019 0.0015 0.0015
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0011 0.0003 0.0023
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.009 0.0123 0.0116
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0011 0.0003 0.0026
Entamoeba histolytica ankyrin repeat protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0206 0.1889
Schistosoma mansoni ephrin receptor 0.0018 0.0013 0.0098
Loa Loa (eye worm) TK/ABL protein kinase 0.0029 0.003 0.0274
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0018 0.0013 0.0098
Entamoeba histolytica serine/threonine kinase, putative 0.0018 0.0013 0.0671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Echinococcus granulosus lamin dm0 0.0053 0.0067 0.0067
Toxoplasma gondii protein kinase domain-containing protein 0.0018 0.0013 0.0425
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0001 0.0012
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Echinococcus multilocularis insulin growth factor binding 0.0019 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Echinococcus granulosus protein tyrosine kinase 0.0018 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0671
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.003 0.1619
Schistosoma mansoni hypothetical protein 0.0034 0.0038 0.0294
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Echinococcus granulosus tyrosine protein kinase Blk 0.0029 0.003 0.003
Brugia malayi Animal haem peroxidase family protein 0.0019 0.0015 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0018 0.0013 0.0115
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0051 0.0051
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.01 0.0138 0.0131
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0011 0.0003 0.0023
Entamoeba histolytica SH2 domain containing protein 0.0011 0.0003 0.003
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0084 0.0658
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0274
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0001 0.0008
Loa Loa (eye worm) histone methyltransferase 0.0009 0 0.0004
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Protein kinase domain containing protein 0.0029 0.003 0.0273
Entamoeba histolytica hypothetical protein, conserved 0.0018 0.0013 0.0671
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0045 0.3794
Brugia malayi Myosin tail family protein 0.0011 0.0003 0.0027
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0019 0.0015 0.0139
Entamoeba histolytica hypothetical protein 0.0019 0.0015 0.0822
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0001 0.0001
Echinococcus multilocularis Spectrin alpha actinin 0.0011 0.0003 0.0003
Echinococcus multilocularis activin receptor type 0.0018 0.0013 0.0013
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0012 0.0004 0.0079
Schistosoma mansoni vesicular amine transporter 0.0028 0.0029 0.0224
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.004 0.0047 0.0047
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0147 1
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0001 0.0008
Echinococcus multilocularis lachesin 0.0028 0.0029 0.0029
Trypanosoma cruzi protein kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0007 0.0054
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0018 0.0013 0.0013
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0018 0.0013 0.0013
Trypanosoma brucei Flagellum attachment zone protein 20 0.0018 0.0013 0.0671
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0067 0.0613
Brugia malayi Protein kinase domain containing protein 0.0029 0.003 0.0273
Brugia malayi hypothetical protein 0.0032 0.0035 0.0318
Trichomonas vaginalis TK family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Echinococcus multilocularis growth factor receptor bound protein 2 0.0023 0.002 0.002
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0003 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0011 0.0003 0.0003
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.003 0.2231
Echinococcus granulosus src region 0.0011 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0016 0.0146
Brugia malayi SH2 domain containing protein 0.0029 0.003 0.0273
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0013 0.0115
Echinococcus granulosus epidermal growth factor receptor kinase 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0052 0.0065 0.06
Echinococcus multilocularis tyrosine protein kinase pr2 0.0018 0.0013 0.0013
Echinococcus multilocularis hemicentin 1 0.0028 0.0029 0.0029
Echinococcus multilocularis geminin 0.0856 0.128 0.128
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0029 0.0269
Echinococcus granulosus tyrosine protein kinase csk 0.0018 0.0013 0.0013
Echinococcus multilocularis ephrin type A receptor 4 A 0.0018 0.0013 0.0013
Toxoplasma gondii thioredoxin reductase 0.004 0.0046 0.2906
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Loa Loa (eye worm) SH2 domain-containing protein 0.0011 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0074 0.0097 0.0893
Echinococcus multilocularis transfer RNA-Thr 0.0018 0.0013 0.0013
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0001 0.0001
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0103 0.0142 0.0142
Onchocerca volvulus 0.0011 0.0003 0.003
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Onchocerca volvulus 0.0011 0.0003 0.0037
Schistosoma mansoni cell adhesion molecule 0.0019 0.0015 0.0118
Onchocerca volvulus Putative cortactin 0.0011 0.0003 0.003
Echinococcus multilocularis protein kinase 0.0018 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0001 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0013 0.0115
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.003 0.1848
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.0118
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0185
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0029 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0022 0.002 0.0155
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Brugia malayi Tyrosine-protein kinase PR2 0.0018 0.0013 0.0115
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0208 0.0208
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0013 0.0674
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0011 0.0003 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0001 0.0008
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.0147 0.014
Echinococcus multilocularis FL cytokine receptor 0.0018 0.0013 0.0013
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0011 0.0003 0.0003
Plasmodium vivax protein kinase, putative 0.0018 0.0013 0.0563
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Brugia malayi SH2 domain containing protein 0.0011 0.0003 0.0031
Entamoeba histolytica serine/threonine kinase, putative 0.0018 0.0013 0.0671
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0081 0.0108 0.7543
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0023
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0018 0.0013 0.0115
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0018 0.0013 0.0098
Schistosoma mansoni lamin 0.0053 0.0067 0.0523
Loa Loa (eye worm) CAMK protein kinase 0.002 0.0016 0.0145
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.02 0.02
Echinococcus multilocularis SH2 motif 0.0011 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis titin 0.0019 0.0015 0.0015
Echinococcus granulosus insulin growth factor binding 0.0019 0.0015 0.0015
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0147 0.1346
Brugia malayi SH2 domain containing protein 0.0011 0.0003 0.0031
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Schistosoma mansoni nephrin 0.0028 0.0029 0.0227
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0264
Onchocerca volvulus 0.0018 0.0013 0.0174
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0053 0.0066 0.0059
Onchocerca volvulus 0.0018 0.0013 0.0174
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0031
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0051 0.3262
Schistosoma mansoni hypothetical protein 0.0018 0.0013 0.0098
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.1848
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0007 0.0273
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0001 0.0001
Entamoeba histolytica serine/threonine kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0019 0.0015 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus growth factor receptor bound protein 2 0.0023 0.002 0.002
Schistosoma mansoni nephrin 0.0047 0.0058 0.0451
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0018 0.0013 0.0115
Echinococcus granulosus titin 0.002 0.0016 0.0016
Entamoeba histolytica ankyrin repeat protein 0.0018 0.0013 0.0671
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0013 0.0013
Brugia malayi CXXC zinc finger family protein 0.0031 0.0032 0.0296
Loa Loa (eye worm) TK/Met protein kinase 0.0018 0.0013 0.0115
Brugia malayi RNA, U transporter 1 0.0082 0.011 0.101
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0108 0.0149 0.1365
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Brugia malayi Thioredoxin reductase 0.004 0.0046 0.0422
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0018 0.0013 0.0013
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Brugia malayi Src substrate cortactin 0.0011 0.0003 0.0027
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0051 0.3262
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0001 0.0008
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0029 0.0266
Onchocerca volvulus 0.0019 0.0015 0.0212
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0001 0.0007
Brugia malayi Prion-like- 0.0019 0.0015 0.0139
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0671
Schistosoma mansoni hypothetical protein 0.0074 0.0097 0.0761
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0081 0.0108 0.7543
Echinococcus multilocularis NCK adaptor protein 0.0023 0.002 0.002
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0011 0.0003 0.0003
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0081 0.0108 0.0108
Brugia malayi Spectrin alpha chain 0.0011 0.0003 0.0027
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0029 0.0266
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine kinase 0.0029 0.003 0.003
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Onchocerca volvulus 0.0018 0.0013 0.0174
Giardia lamblia Kinase, NEK 0.0018 0.0013 0.1484
Schistosoma mansoni hypothetical protein 0.0308 0.0452 0.3528
Plasmodium falciparum protein kinase, putative 0.0018 0.0013 0.0632
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0047 0.0047
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0011 0.0003 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Brugia malayi Variant SH3 domain containing protein 0.0023 0.002 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0671
Schistosoma mansoni cell adhesion molecule 0.0028 0.0029 0.0227
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Plasmodium falciparum tyrosine kinase-like protein 0.0018 0.0013 0.0563
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0029 0.003 0.003
Loa Loa (eye worm) SH2 domain-containing protein 0.0011 0.0003 0.0031
Echinococcus granulosus neuroglian 0.0028 0.0029 0.0029
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0018 0.0013 0.0013
Echinococcus granulosus receptor type guanylyl cyclase 0.0018 0.0013 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0013 0.0098
Schistosoma mansoni titin 0.0019 0.0015 0.0118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Echinococcus granulosus neuroglian 0.0047 0.0058 0.0058
Echinococcus multilocularis kinase suppressor of Ras 1 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Plasmodium falciparum glutathione reductase 0.004 0.0046 0.3852
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.0147 0.1346
Brugia malayi Immunoglobulin I-set domain containing protein 0.0473 0.0702 0.6432
Schistosoma mansoni titin 0.002 0.0016 0.0124
Echinococcus multilocularis transfer RNA-Ala 0.0011 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0029 0.003 0.0273
Giardia lamblia Protein 21.1 0.0018 0.0013 0.1484
Entamoeba histolytica hypothetical protein 0.0035 0.0039 0.2533
Trichomonas vaginalis TKL family protein kinase 0.0019 0.0015 0.0822
Mycobacterium tuberculosis Probable reductase 0.009 0.0123 0.0116
Echinococcus granulosus peptidase Clp S14 family 0.0053 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.0118
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0266
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis tyrosine protein kinase Blk 0.0029 0.003 0.003
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.009 0.0701
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0001 0.0008
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0007 0.0007
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0018 0.0013 0.0013
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0018 0.0013 0.0115
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.002 0.002
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0018 0.0013 0.0671
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0021 0.1288
Echinococcus granulosus SH2 motif 0.0011 0.0003 0.0003
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0027
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0018 0.0013 0.0013
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0266
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Loa Loa (eye worm) hypothetical protein 0.0085 0.0115 0.1057
Brugia malayi Tyrosine-protein kinase abl-1 0.004 0.0047 0.0428
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0037 0.0042 0.0042
Plasmodium vivax importin-beta 2, putative 0.0029 0.003 0.225
Schistosoma mansoni suppressor of cytokine signaling 0.0011 0.0003 0.0026
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0047 0.0047
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0011 0.0003 0.0003
Echinococcus granulosus retinal guanylyl cyclase 2 0.0018 0.0013 0.0013
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0081 0.0108 0.0102
Brugia malayi SH2 domain containing protein 0.0011 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.023
Trichomonas vaginalis ran, putative 0.0021 0.0018 0.1061
Brugia malayi Protein kinase domain containing protein 0.0176 0.0253 0.2318
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0011 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.0147 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0018 0.0013 0.0671
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0671
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0029 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Echinococcus multilocularis receptor type guanylyl cyclase 0.0018 0.0013 0.0013
Toxoplasma gondii melibiase subfamily protein 0.0103 0.0142 1
Brugia malayi steroid hormone receptor 0.001 0.0001 0.0008
Schistosoma mansoni lamin 0.0053 0.0067 0.0523
Brugia malayi hypothetical protein 0.0035 0.0039 0.0361
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis tyrosine protein kinase csk 0.0018 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0023
Echinococcus granulosus expressed conserved protein 0.0011 0.0003 0.0003
Echinococcus granulosus titin 0.0019 0.0015 0.0015
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Brugia malayi cytokine inducible SH2-containing protein 5 0.0011 0.0003 0.0031
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.009 0.0123 0.0339
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0147 1
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Echinococcus granulosus activated cdc42 kinase 1 0.0018 0.0013 0.0013
Echinococcus multilocularis thymidine phosphorylase 0.6625 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0217
Loa Loa (eye worm) TK/CSK protein kinase 0.0018 0.0013 0.0115
Loa Loa (eye worm) SRC-1 0.004 0.0047 0.0428
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.004 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0345
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0001 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0208 0.1627
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.0147 0.1147
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni C-fyn 0.0011 0.0003 0.0023
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0039 0.0039
Brugia malayi Sex muscle abnormal protein 5 0.0023 0.002 0.0185
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0038 0.0345
Trichomonas vaginalis STE family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0011 0.0003 0.0003
Brugia malayi Leucine Rich Repeat family protein 0.0019 0.0016 0.0142
Onchocerca volvulus 0.0029 0.003 0.043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0001 0.0008
Schistosoma mansoni adapter molecule crk 0.0023 0.002 0.0158
Brugia malayi Guanylate kinase family protein 0.0011 0.0003 0.0027
Onchocerca volvulus 0.0011 0.0003 0.003
Onchocerca volvulus 0.0011 0.0003 0.003
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Schistosoma mansoni titin 0.0019 0.0015 0.0118
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Onchocerca volvulus 0.0085 0.0115 0.1698
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.0147 0.0147
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0001 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0208 0.1627
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0001 0.0008
Loa Loa (eye worm) TK/FAK protein kinase 0.0018 0.0013 0.0115
Echinococcus multilocularis expressed protein 0.0011 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis hemicentin 1 0.0028 0.0029 0.0029
Echinococcus granulosus GPCR family 2 0.0034 0.0038 0.0038
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0018 0.0013 0.0671
Schistosoma mansoni cell adhesion molecule 0.0019 0.0015 0.0118
Trypanosoma brucei Pseudokinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine protein kinase ABL1 0.0029 0.003 0.003
Onchocerca volvulus 0.0019 0.0015 0.0212
Echinococcus granulosus SHC transforming protein 3 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0217
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0018 0.0013 0.0013
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0011 0.0003 0.0023
Echinococcus granulosus SH2 domain containing protein 7 0.0011 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) hypothetical protein 0.0053 0.0067 0.0614
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0029 0.003 0.003
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0147 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0028 0.2106
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.003 0.2231
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0657
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0029 0.0269
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0473 0.0702 0.6434
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0208 0.0208
Echinococcus granulosus epidermal growth factor receptor 0.0018 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0035 0.0039 0.2533
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0028 0.2106
Onchocerca volvulus 0.002 0.0016 0.0222
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0027
Onchocerca volvulus 0.0011 0.0003 0.0037
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) RGC/RGC protein kinase 0.0018 0.0013 0.0115
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0079 0.5363
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0019 0.0016 0.0016
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0015 0.0015
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0028 0.0029 0.0224
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0011 0.0003 0.0023
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0018 0.0013 0.0425
Entamoeba histolytica protein kinase, putative 0.0012 0.0004 0.0079
Echinococcus multilocularis tyrosine protein kinase csk 0.0018 0.0013 0.0013
Schistosoma mansoni septate junction protein 0.0028 0.0029 0.0227
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0038 0.0038
Onchocerca volvulus 0.0053 0.0067 0.0981
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0264
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0081 0.0108 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0001 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Brugia malayi Melibiase family protein 0.0069 0.009 0.0823
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0013 0.0013
Loa Loa (eye worm) disorganized muscle protein 1 0.0019 0.0015 0.0139
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0178 0.0255 0.0255
Brugia malayi hypothetical protein 0.0011 0.0003 0.0031
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0018 0.0013 0.0013
Echinococcus granulosus defective proboscis extension response 0.0028 0.0029 0.0029
Loa Loa (eye worm) TK protein kinase 0.0029 0.003 0.0274
Brugia malayi Peripheral plasma membrane protein CASK 0.0011 0.0003 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0013 0.0671
Brugia malayi SRC-1 0.004 0.0047 0.0428
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0142 0.1106
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus signal transduction protein lnk realted 0.0011 0.0003 0.0003
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0104
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0266
Echinococcus multilocularis 0.0011 0.0003 0.0003
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0011 0.0003 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Echinococcus granulosus importin subunit beta 1 0.0029 0.003 0.003
Echinococcus multilocularis tyrosine protein kinase Abl 0.004 0.0047 0.0047
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) TK/INSR protein kinase 0.0018 0.0013 0.0115
Plasmodium falciparum tyrosine kinase-like protein 0.0018 0.0013 0.0563
Schistosoma mansoni tensin 0.0011 0.0003 0.0026
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi SH2 domain containing protein 0.0029 0.003 0.0273
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.0118
Brugia malayi intermediate filament protein 0.0053 0.0067 0.0613
Loa Loa (eye worm) TK/EGFR protein kinase 0.0018 0.0013 0.0115
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.072
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Echinococcus granulosus expressed protein 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0029 0.003 0.043
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.002 0.002
Echinococcus multilocularis Immunoglobulin 0.0028 0.0029 0.0029
Schistosoma mansoni signal transduction protein lnk-related 0.0011 0.0003 0.0026
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis tyrosine protein kinase csk 0.0018 0.0013 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0046 0.2993
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0016 0.0142
Mycobacterium ulcerans thymidine phosphorylase 0.6625 1 1
Brugia malayi ecdysteroid receptor 0.001 0.0001 0.0008
Schistosoma mansoni ran 0.0021 0.0018 0.0142
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Echinococcus multilocularis titin 0.0019 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0034 0.0038 0.0294
Loa Loa (eye worm) STAT protein 0.0011 0.0003 0.0031
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.0147 0.014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0266
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0018 0.1061
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Onchocerca volvulus 0.0019 0.0015 0.0212
Schistosoma mansoni septate junction protein 0.0028 0.0029 0.0227
Schistosoma mansoni tensin-related 0.0011 0.0003 0.0026
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0018 0.0013 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Onchocerca volvulus 0.0029 0.003 0.043
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0018 0.0167
Echinococcus multilocularis cpg binding protein 0.0032 0.0035 0.0035
Leishmania major trypanothione reductase 0.004 0.0046 0.2993
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0021 0.1288
Echinococcus granulosus protein kinase 0.0018 0.0013 0.0013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0003 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0001 0.0008
Loa Loa (eye worm) guanylate kinase 0.0011 0.0003 0.0027
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0001 0.0007
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0001 0.0008
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0045 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0018 0.0013 0.0013
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0001 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Schistosoma mansoni ap endonuclease 0.002 0.0016 0.0124
Trypanosoma brucei trypanothione reductase 0.004 0.0046 0.2993
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0013 0.0115
Schistosoma mansoni tyrosine kinase 0.004 0.0047 0.0364
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0029 0.003 0.187
Echinococcus multilocularis neuroglian 0.0047 0.0058 0.0058
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus ephrin type A receptor 4 A 0.0018 0.0013 0.0013
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0001 0.0001
Schistosoma mansoni GTPase activating protein 0.0011 0.0003 0.0026
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0023 0.002 0.0185
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.004 0.0047 0.0047
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0051 0.3326
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0018 0.0013 0.0013
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0016 0.09
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0018 0.0013 0.0115
Brugia malayi Receptor family ligand binding region containing protein 0.0018 0.0013 0.0115
Echinococcus granulosus retinal guanylyl cyclase 2 0.0018 0.0013 0.0013
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0018 0.0013 0.0013
Giardia lamblia Kinase, NEK 0.0018 0.0013 0.1484
Echinococcus granulosus tensin 0.0011 0.0003 0.0003
Schistosoma mansoni hemicentin 0.0019 0.0015 0.0118
Schistosoma mansoni sorbin 0.0011 0.0003 0.0023
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0011 0.0003 0.0027
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0016 0.09
Echinococcus granulosus MAM 0.0085 0.0115 0.0115
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0001 0.0007
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0018 0.0013 0.0013
Brugia malayi bone morphogenetic protein type 1 receptor 0.0018 0.0013 0.0115
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Plasmodium falciparum protein kinase, putative 0.0018 0.0013 0.0563
Entamoeba histolytica tyrosin kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus contactin 0.0028 0.0029 0.0029
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.0118
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0015 0.0139
Schistosoma mansoni hypothetical protein 0.0085 0.0115 0.09
Schistosoma mansoni thyroid hormone receptor 0.001 0.0001 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0013 0.0098
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0018 0.1116
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0696
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0016 0.0645
Echinococcus granulosus kinase suppressor of Ras 1 0.0018 0.0013 0.0013
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Brugia malayi N-terminal motif family protein 0.0181 0.026 0.2384
Brugia malayi nuclear receptor NHR-88 0.001 0.0001 0.0008
Brugia malayi Protein kinase domain containing protein 0.0029 0.003 0.0273
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0272
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0027
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0018 0.0013 0.0174
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Echinococcus granulosus intermediate filament protein 0.0053 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Onchocerca volvulus 0.0011 0.0003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0013 0.0115
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) RGC/RGC protein kinase 0.0018 0.0013 0.0115
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Echinococcus granulosus epidermal growth factor receptor 0.0018 0.0013 0.0013
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0001 0.0001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0016 0.09
Schistosoma mansoni cell adhesion molecule 0.0037 0.0043 0.0333
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Echinococcus multilocularis tensin 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.003 0.1683
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.01 0.0138 0.0131
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0 0.0002
Echinococcus granulosus titin 0.002 0.0016 0.0016
Giardia lamblia Kinase 0.0018 0.0013 0.1484
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Echinococcus granulosus SH2 domain containing adapter protein F 0.0011 0.0003 0.0003
Loa Loa (eye worm) TK protein kinase 0.0037 0.0042 0.0382
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0046 0.0039
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Loa Loa (eye worm) TK/EPH protein kinase 0.0018 0.0013 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0001 0.0008
Schistosoma mansoni tensin-related 0.0011 0.0003 0.0026
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0011 0.0003 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase csk 0.0018 0.0013 0.0013
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0001 0.0007
Echinococcus multilocularis tensin 0.0011 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0001 0.0008
Echinococcus granulosus roundabout 2 0.0028 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0001 0.0008
Brugia malayi Peroxidasin 0.0029 0.0029 0.027
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.0452 0.4142
Leishmania major protein kinase, putative 0.0018 0.0013 0.0671
Plasmodium falciparum thioredoxin reductase 0.004 0.0046 0.3852
Brugia malayi Tensin 0.0011 0.0003 0.0031
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0097 0.0893
Onchocerca volvulus 0.0018 0.0013 0.0174
Schistosoma mansoni Dab2-interacting protein-like 0.0011 0.0003 0.0023
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0015 0.0139
Loa Loa (eye worm) animal heme peroxidase 0.0019 0.0015 0.0139
Echinococcus granulosus tyrosine protein kinase csk 0.0018 0.0013 0.0013
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0104
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0018 0.0013 0.0098
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0013 0.0013
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0051 0.4324
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Onchocerca volvulus 0.0018 0.0013 0.0174
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus roundabout 2 0.0028 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0001 0.0008
Schistosoma mansoni cell adhesion molecule 0.0028 0.0029 0.0227
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Brugia malayi Furin-like cysteine rich region family protein 0.0018 0.0013 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0016 0.0124
Echinococcus multilocularis tyrosine kinase 0.0029 0.003 0.003
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0027
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0061 0.4057
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0038 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0029 0.0029
Toxoplasma gondii hypothetical protein 0.0028 0.0028 0.1589
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.0208 0.1909
Echinococcus multilocularis down syndrome cell adhesion 0.0019 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0018 0.0013 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0013 0.0674
Leishmania major hypothetical protein, conserved 0.005 0.0061 0.4057
Entamoeba histolytica receptor protein kinase, putative 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0011 0.0003 0.0003
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Schistosoma mansoni titin 0.0019 0.0015 0.0118
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0081 0.0108 0.0108
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0018 0.0013 0.0098
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0007 0.0273
Onchocerca volvulus 0.0011 0.0003 0.0037
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0013 0.0674
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1645 0.2473 0.2473
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0011 0.0003 0.0026
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Echinococcus multilocularis 0.0019 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0671
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0081 0.0108 0.0288
Echinococcus granulosus twitchin 0.0048 0.0058 0.0058
Loa Loa (eye worm) TK/RYK protein kinase 0.0018 0.0013 0.0115
Schistosoma mansoni tyrosine kinase 0.004 0.0047 0.0364
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0016 0.0888
Loa Loa (eye worm) protein kinase domain-containing protein 0.0018 0.0013 0.0115
Leishmania major importin beta-1 subunit, putative 0.0023 0.0021 0.1288
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0067 0.0614
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0001 0.0007
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.0118
Schistosoma mansoni titin 0.0028 0.0029 0.0227
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0023 0.002 0.0158
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0013 0.0006
Onchocerca volvulus 0.0029 0.003 0.043
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0029 0.0266
Brugia malayi Guanylyl cyclase protein 23 0.0018 0.0013 0.0115
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.003 0.2231
Schistosoma mansoni titin 0.0019 0.0015 0.0118
Schistosoma mansoni tyrosine kinase 0.0046 0.0056 0.0434
Echinococcus granulosus Spectrin alpha actinin 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0019 0.0015 0.0212
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Echinococcus multilocularis tyrosine protein kinase 0.0018 0.0013 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0208 0.1627
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0053 0.0066 0.0059
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0019 0.0015 0.0118
Toxoplasma gondii protein kinase 0.0018 0.0013 0.0425
Onchocerca volvulus Peroxidasin homolog 0.0019 0.0015 0.0212
Loa Loa (eye worm) TK/ALK protein kinase 0.0731 0.109 1
Brugia malayi Fes/CIP4 homology domain containing protein 0.0011 0.0003 0.0027
Echinococcus multilocularis snurportin 1 0.0308 0.0452 0.0452
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0016 0.0016
Brugia malayi hypothetical protein 0.0018 0.0013 0.0115
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0263
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0027
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0018 0.1116
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0001 0.0008
Schistosoma mansoni ran 0.0021 0.0018 0.0142
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0018 0.1061
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0001 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Onchocerca volvulus 0.0018 0.0013 0.0174
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.009 0.0701
Echinococcus multilocularis neuroglian 0.0028 0.0029 0.0029
Echinococcus granulosus tyrosine protein kinase shark 0.0029 0.003 0.003
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0018 0.2942
Echinococcus multilocularis lamin dm0 0.0053 0.0067 0.0067
Schistosoma mansoni growth factor receptor-bound protein 0.0023 0.002 0.0158
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0264
Echinococcus granulosus lamin 0.0053 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0085 0.0115 0.1057
Entamoeba histolytica cysteine surface protein, putative 0.0018 0.0013 0.0671
Leishmania major hypothetical protein, conserved 0.0018 0.0013 0.0671
Schistosoma mansoni hypothetical protein 0.0034 0.0038 0.0294
Onchocerca volvulus 0.0018 0.0013 0.0174
Onchocerca volvulus 0.0019 0.0015 0.0212
Brugia malayi hypothetical protein 0.0029 0.003 0.0273
Schistosoma mansoni tensin 0.0011 0.0003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Onchocerca volvulus 0.0018 0.0013 0.0174
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0013 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine protein kinase Btk29A 0.004 0.0047 0.0047
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0013 0.0428
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Schistosoma mansoni hypothetical protein 0.0085 0.0115 0.09
Entamoeba histolytica tyrosin kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis protein tyrosine kinase 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0266
Mycobacterium tuberculosis Probable dehydrogenase 0.009 0.0123 0.0116
Entamoeba histolytica serine/threonine kinase, putative 0.0018 0.0013 0.0671
Echinococcus multilocularis MAM 0.0085 0.0115 0.0115
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0671
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0013 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0016 0.0124
Echinococcus multilocularis titin 0.002 0.0016 0.0016
Onchocerca volvulus 0.0031 0.0032 0.0467
Echinococcus multilocularis tyrosine protein kinase otk 0.0028 0.0029 0.0029
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0018 0.0013 0.0425
Brugia malayi Prion-like- 0.0019 0.0015 0.0139
Echinococcus multilocularis roundabout 2 0.0057 0.0072 0.0072
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0019 0.0015 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Schistosoma mansoni tyrosine kinase 0.0029 0.003 0.0233
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0013 0.0013
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0028 0.0029 0.0029
Brugia malayi Calcitonin receptor-like protein seb-1 0.0108 0.0149 0.1365
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni run and tbc1 domain containing 0.0011 0.0003 0.0023
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0019 0.0016 0.0016
Brugia malayi kettin 0.0019 0.0015 0.0139
Echinococcus multilocularis roundabout 2 0.0028 0.0029 0.0029
Brugia malayi Prion-like- 0.0019 0.0015 0.0139
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.0147 1
Onchocerca volvulus 0.0418 0.0619 0.9175
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.004 0.0047 0.0364
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0028 0.0029 0.0029
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0081 0.0108 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0018 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni tensin 0.0011 0.0003 0.0026
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0001 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0021 0.1288
Loa Loa (eye worm) acetyltransferase 0.0146 0.0206 0.189
Echinococcus multilocularis SH2 domain containing protein 7 0.0011 0.0003 0.0003
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0001 0.0007
Schistosoma mansoni cell adhesion molecule 0.0019 0.0015 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0001 0.0008
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0018 0.0013 0.0671
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0007 0.0273
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus N chimaerin 0.0011 0.0003 0.0003
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0061 0.536
Loa Loa (eye worm) RGC/RGC protein kinase 0.0018 0.0013 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0266
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0038 0.0345
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.003 0.1848
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0008 0.0063
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0003 0.0031
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0018 0.0013 0.0013
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0001 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Echinococcus granulosus integrin linked protein kinase 0.0018 0.0013 0.0013
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0069 0.009 0.6035
Onchocerca volvulus 0.0053 0.0067 0.0981
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0061 0.4057
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Echinococcus granulosus hemicentin 1 0.0028 0.0029 0.0029
Echinococcus granulosus NCK adaptor protein 0.0023 0.002 0.002
Echinococcus granulosus Immunoglobulin 0.0028 0.0029 0.0029
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0007 0.0063
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0671
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus fch and double sh3 domains protein 2 0.0011 0.0003 0.0003
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0038 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus activin receptor type 0.0018 0.0013 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.1848
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.01 0.0138 0.0394
Onchocerca volvulus 0.0085 0.0115 0.1698
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0011 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0042 0.0381
Leishmania major GTP-binding protein, putative 0.0021 0.0018 0.1061
Brugia malayi tRNA modification GTPase TrmE family protein 0.0011 0.0003 0.0031
Echinococcus granulosus FTZ F1 alpha 0.001 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Echinococcus multilocularis peptidase Clp (S14 family) 0.0053 0.0066 0.0066
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0391
Brugia malayi 6-phosphofructokinase 0.0106 0.0147 0.1346
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.6625 1 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0061 0.0562
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.187 0.2813 0.2808
Schistosoma mansoni roundabout 0.0028 0.0029 0.0227
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Onchocerca volvulus 0.0019 0.0015 0.0212
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0018 0.0013 0.0013
Brugia malayi hypothetical protein 0.0018 0.0013 0.0115
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0001 0.0008
Brugia malayi nuclear hormone receptor 0.001 0.0001 0.0008
Echinococcus granulosus leucine rich repeat containing protein 4 0.0019 0.0015 0.0015
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0001 0.0001
Echinococcus granulosus natriuretic peptide receptor 1 0.0018 0.0013 0.0013
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0067 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0671
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0015 0.0139
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0018 0.0013 0.0174
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.004 0.0047 0.0047
Echinococcus granulosus SH2 motif 0.0011 0.0003 0.0003
Loa Loa (eye worm) serine/threonine protein kinase 0.0018 0.0013 0.0115
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0013 0.072
Schistosoma mansoni tyrosine kinase 0.0018 0.0013 0.0098
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0027
Brugia malayi isocitrate dehydrogenase 0.0018 0.0013 0.0116
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0003 0.0003
Schistosoma mansoni eps8-related protein 0.0011 0.0003 0.0023
Onchocerca volvulus Peroxidasin homolog 0.0021 0.0018 0.025
Schistosoma mansoni cpg binding protein 0.0031 0.0032 0.0253
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0013 0.0116
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0104
Echinococcus granulosus suppressor of cytokine signaling 6 0.0011 0.0003 0.0003
Echinococcus granulosus cpg binding protein 0.0032 0.0035 0.0035
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0018 0.0013 0.0098
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0045 0.2952
Echinococcus granulosus insulin receptor 0.0018 0.0013 0.0013
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0028 0.1529
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0018 0.0013 0.0696
Echinococcus multilocularis tyrosine protein kinase Fgr 0.004 0.0047 0.0047
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine protein kinase Srms 0.0029 0.003 0.003
Trichomonas vaginalis protein tyrosine kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0031
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0026
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0013 0.0567
Plasmodium vivax glutathione reductase, putative 0.004 0.0046 0.3852
Onchocerca volvulus 0.0019 0.0015 0.0212
Loa Loa (eye worm) hypothetical protein 0.0081 0.0108 0.0995
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0018 0.0013 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0013 0.0115
Echinococcus multilocularis roundabout 2 0.0028 0.0029 0.0029
Echinococcus multilocularis lamin 0.0053 0.0067 0.0067
Echinococcus granulosus tyrosine protein kinase pr2 0.0018 0.0013 0.0013
Echinococcus granulosus peroxidasin 0.0029 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Echinococcus multilocularis SHC transforming protein 3 0.0011 0.0003 0.0003
Brugia malayi SH3 domain containing protein 0.0011 0.0003 0.0027
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0081 0.0108 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0115 0.1057
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0264
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Schistosoma mansoni intermediate filament proteins 0.0053 0.0067 0.0523
Echinococcus granulosus down syndrome cell adhesion 0.0019 0.0015 0.0015
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.003 0.2231
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni dynamin-associated protein 0.0011 0.0003 0.0023
Brugia malayi Disorganized muscle protein 1 0.0019 0.0015 0.0139
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0018 0.0013 0.0013
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0011 0.0003 0.0003
Brugia malayi Variant SH3 domain containing protein 0.0023 0.002 0.0185
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0007 0.0273
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Echinococcus multilocularis Immunoglobulin 0.0028 0.0029 0.0029
Brugia malayi hypothetical protein 0.0028 0.0029 0.0263
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0037 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0115
Loa Loa (eye worm) hypothetical protein 0.0181 0.026 0.2385
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Echinococcus multilocularis tyrosine protein kinase csk 0.0018 0.0013 0.0013
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0029 0.0266
Brugia malayi C-terminal src kinase protein 1 0.0018 0.0013 0.0115
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0018 0.0013 0.0477
Loa Loa (eye worm) TK protein kinase 0.0018 0.0013 0.0115
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0037 0.0043 0.0043
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0018 0.0013 0.0013
Loa Loa (eye worm) TK/ROR protein kinase 0.0037 0.0042 0.0382
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0011 0.0003 0.003
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0019 0.0015 0.0015
Echinococcus granulosus endophilin A3 0.0011 0.0003 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0208 0.0208
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0019 0.0015 0.0139
Schistosoma mansoni tyrosine kinase 0.004 0.0047 0.0364
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0061 0.4043
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0016 0.09
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni neuroglian 0.0028 0.0029 0.0227
Loa Loa (eye worm) TK/FER protein kinase 0.0018 0.0013 0.0115
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.004 0.0047 0.0047
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.187 0.2813 0.2808
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.003 0.1697
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0013 0.072
Toxoplasma gondii Alpha-galactosidase 0.0015 0.0008 0.0093
Echinococcus granulosus nostrin 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0069 0.009 0.0823
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0011 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0671
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0176 0.0253 0.2318
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Entamoeba histolytica hypothetical protein 0.0018 0.0013 0.0671
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.1848
Schistosoma mansoni hypothetical protein 0.0035 0.0039 0.0308
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0007 0.0273
Echinococcus granulosus tyrosine protein kinase Fyn 0.004 0.0047 0.0047
Brugia malayi SH2 domain containing protein 0.0011 0.0003 0.0031
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Onchocerca volvulus 0.0011 0.0003 0.003
Onchocerca volvulus 0.0018 0.0013 0.0174
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Schistosoma mansoni hypothetical protein 0.0019 0.0015 0.0118
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0007 0.0273
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Echinococcus granulosus titin 0.0019 0.0015 0.0015
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0018 0.0013 0.0115
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0015 0.0139
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0007 0.0273
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi Variant SH3 domain containing protein 0.0011 0.0003 0.0031
Schistosoma mansoni cell polarity protein 0.0011 0.0003 0.0023
Entamoeba histolytica protein kinase domain containing protein 0.0018 0.0013 0.0671
Brugia malayi RhoGAP domain containing protein 0.0011 0.0003 0.0031
Toxoplasma gondii exonuclease III APE 0.002 0.0016 0.067
Trypanosoma cruzi protein kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0011 0.0003 0.0026
Schistosoma mansoni tyrosine kinase 0.0029 0.003 0.0233
Entamoeba histolytica protein kinase, putative 0.0018 0.0013 0.0696
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.1288
Echinococcus multilocularis importin subunit beta 1 0.0029 0.003 0.003
Schistosoma mansoni cpg binding protein 0.0032 0.0035 0.0273
Brugia malayi Protein kinase domain containing protein 0.0029 0.003 0.0273
Brugia malayi integrin-linked kinase 0.0018 0.0013 0.0115
Loa Loa (eye worm) hypothetical protein 0.0108 0.0149 0.1365
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0018 0.0013 0.0115
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0028 0.0029 0.0227
Echinococcus multilocularis insulin receptor 0.0018 0.0013 0.0013
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.0147 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0016 0.0146
Echinococcus multilocularis epidermal growth factor receptor 0.0018 0.0013 0.0013
Echinococcus granulosus fibroblast growth factor receptor 4 0.0018 0.0013 0.0013
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0038 0.0038
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0018 0.0013 0.0098
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0081 0.0108 1
Entamoeba histolytica tyrosine kinase, putative 0.0018 0.0013 0.0671
Schistosoma mansoni titin 0.0019 0.0015 0.0118
Brugia malayi Protein kinase domain containing protein 0.0018 0.0013 0.0115
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0029 0.0029
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0001 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0 0.0003
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0013 0.0013
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0018 0.0013 0.0671
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0142 0.1106
Mycobacterium tuberculosis Putative ferredoxin reductase 0.009 0.0123 0.0116
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Brugia malayi hypothetical protein 0.0085 0.0115 0.1056
Loa Loa (eye worm) TK/DDR protein kinase 0.0018 0.0013 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0018 0.0013 0.0671
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0001 0.0001
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0053 0.0066 0.0137
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0011 0.0003 0.0031
Schistosoma mansoni peptidase Clp (S14 family) 0.0081 0.0108 0.0847
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.003 0.1862
Schistosoma mansoni protein kinase 0.0018 0.0013 0.0098
Schistosoma mansoni cell adhesion molecule 0.0028 0.0029 0.0227
Schistosoma mansoni slit 0.0019 0.0016 0.0121
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0018 0.0013 0.0671
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0028 0.0029 0.0227
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0016 0.09
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0001 0.0001
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0103 0.0142 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.003 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0671
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0061 0.536
Schistosoma mansoni ap endonuclease 0.002 0.0016 0.0124
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0028 0.0029 0.0029
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.003 0.5881
Echinococcus granulosus tyrosine kinase 0.0029 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0139
Echinococcus multilocularis tyrosine protein kinase Srms 0.0029 0.003 0.003
Trypanosoma brucei protein kinase, putative 0.0018 0.0013 0.072

Activities

Activity type Activity value Assay description Source Reference
Change (functional) = -10.9 % Mean change in heart rate recorded 14 min after the administration of compound. ChEMBL. 3005568
EC25 (functional) = 5.06 ug ml-1 Concentration required to reduce maximum following frequencu (MFF) of isolated guinea pig atria by 25% ChEMBL. 3005568
ED50 (functional) < 0.2 mg kg-1 Compound that antagonized arrhythmias evoked by coronary artery ligation in the rat was measured at 0.2 mg/kg dose ChEMBL. 3005568
ED50 (functional) = 9 mg kg-1 ED 50 value against aconitine-induced arrhythmias in mice ChEMBL. 3005568
Heart rate (functional) = 359 beats min-1 Effect of the compound on heart rate after isoprenaline induced tachycardia in the anesthetized rat at 0.2 mg/kg dose ChEMBL. 3005568
Heart rate (functional) = 392 beats min-1 Effect of the compound on heart rate 1 min post isoprenaline induced tachycardia in the anesthetized rat at 0.2 mg/kg dose. ChEMBL. 3005568
Heart rate (functional) = 403 beats min-1 Effect of the compound on heart rate before isoprenaline induced tachycardia in the anesthetized rat at 0.2 mg/kg dose ChEMBL. 3005568
Increase (functional) = 9.2 % Maximum increase in heart rate evoked by isoprenaline. ChEMBL. 3005568
VF (functional) = 29 % Compound was tested for antagonism of Ventricular Fibrilloflutter (VF) evoked by coronary artery ligation in the rat measured at 0.2 mg/kg dose ChEMBL. 3005568

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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