Detailed information for compound 1402394

Basic information

Technical information
  • TDR Targets ID: 1402394
  • Name: 5-prop-2-ynylsulfanyl-2H-1,2,4-triazol-3-amin e
  • MW: 154.193 | Formula: C5H6N4S
  • H donors: 2 H acceptors: 2 LogP: 0.6 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCSc1n[nH]c(n1)N
  • InChi: 1S/C5H6N4S/c1-2-3-10-5-7-4(6)8-9-5/h1H,3H2,(H3,6,7,8,9)
  • InChiKey: RPHHSSICXHMIAH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 5-(prop-2-ynylthio)-2H-1,2,4-triazol-3-amine
  • [5-(propargylthio)-2H-1,2,4-triazol-3-yl]amine
  • 3-(prop-2-ynylthio)-1H-1,2,4-triazol-5-amine
  • TOS-BB-1197
  • ZINC02353760
  • 11G-051
  • MLS-0111631.0001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis regulator of G protein signaling 0.0477 0.1517 0.1806
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus epidermal growth factor receptor 0.0051 0.005 0.005
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0044 0.0026 0.002
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0067 0.0276
Schistosoma mansoni hypothetical protein 0.0143 0.0367 0.0347
Echinococcus multilocularis rac serine:threonine kinase 0.0056 0.0067 0.007
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0067 0.4571
Loa Loa (eye worm) hypothetical protein 0.0326 0.0997 0.099
Echinococcus multilocularis G protein coupled receptor kinase 1 0.1778 0.5995 0.7169
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0044 0.0026 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0143 0.0367 0.2419
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Brugia malayi probable spectrin beta chain 0.0044 0.0026 0.0017
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0051 0.005 0.005
Loa Loa (eye worm) RGS-3 protein 0.0477 0.1517 0.1509
Echinococcus multilocularis oxysterol binding protein 1 0.0044 0.0026 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.005 0.0332
Onchocerca volvulus 0.0051 0.005 0.0099
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0051 0.005 0.005
Onchocerca volvulus 0.0051 0.005 0.0099
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Loa Loa (eye worm) TK/ABL protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni rho gtpase activating protein 0.0044 0.0026 0.0005
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0477 0.1517 0.1499
Echinococcus granulosus epidermal growth factor receptor 0.0051 0.005 0.005
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trichomonas vaginalis centaurin/arf, putative 0.0044 0.0026 0.017
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis epidermal growth factor receptor 0.0051 0.005 0.005
Loa Loa (eye worm) TK/ROR protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.005 0.0029
Echinococcus granulosus twitchin 0.0125 0.0305 0.0355
Echinococcus multilocularis aurora kinase A 0.007 0.0116 0.0128
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Loa Loa (eye worm) cytohesin 3 0.0044 0.0026 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) TK/EPH protein kinase 0.0051 0.005 0.0042
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Entamoeba histolytica protein kinase, putative 0.007 0.0116 0.0603
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0051 0.005 0.005
Trichomonas vaginalis kinesin light chain, putative 0.0044 0.0026 0.017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) hypothetical protein 0.0113 0.0264 0.0256
Trypanosoma cruzi aurora B kinase, putative 0.007 0.0116 1
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0005
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0044 0.0026 0.002
Echinococcus multilocularis Immunoglobulin 0.0113 0.0264 0.0306
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0051 0.005 0.005
Echinococcus multilocularis exocyst complex component 2 0.0143 0.0367 0.0429
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Loa Loa (eye worm) TK/FAK protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0367 0.2419
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Onchocerca volvulus 0.0051 0.005 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus multilocularis Pleckstrin y 0.0044 0.0026 0.002
Entamoeba histolytica hypothetical protein 0.0056 0.0067 0.0276
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Brugia malayi Regulator of G protein signaling domain containing protein 0.0477 0.1517 0.1509
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus granulosus tyrosine protein kinase ABL1 0.0051 0.005 0.005
Echinococcus granulosus serine/threonine protein kinase 0.0056 0.0067 0.007
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0044 0.0026 0.017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus oxysterol binding protein 3 0.0044 0.0026 0.002
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0044 0.0026 0.0017
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trichomonas vaginalis centaurin beta, putative 0.0044 0.0026 0.017
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Entamoeba histolytica hypothetical protein 0.0143 0.0367 0.2288
Echinococcus granulosus tyrosine protein kinase 0.0051 0.005 0.005
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Brugia malayi SH2 domain containing protein 0.0051 0.005 0.0042
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Schistosoma mansoni protein kinase 0.0063 0.0092 0.0071
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.005 0.005
Trichomonas vaginalis protein transport protein sec7, putative 0.0044 0.0026 0.017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) TK/DDR protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0056 0.0067 0.4571
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Plasmodium falciparum calcium-dependent protein kinase 7 0.0056 0.0067 0.4571
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0051 0.005 0.0166
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0051 0.005 0.005
Echinococcus multilocularis tyrosine protein kinase Blk 0.0051 0.005 0.005
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Echinococcus granulosus tyrosine kinase 0.0051 0.005 0.005
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0051 0.005 0.005
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0477 0.1517 0.1499
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0051 0.005 0.0042
Trichomonas vaginalis TK family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Leishmania major protein kinase, putative 0.0051 0.005 0.2744
Loa Loa (eye worm) hypothetical protein 0.0113 0.0264 0.0256
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0051 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0051 0.005 0.005
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Loa Loa (eye worm) hypothetical protein 0.0113 0.0264 0.0256
Echinococcus granulosus insulin receptor 0.0051 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Giardia lamblia Aurora kinase 0.007 0.0116 1
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0051 0.005 0.005
Plasmodium vivax serine/threonine protein kinase 6, putative 0.007 0.0116 1
Plasmodium vivax protein kinase, putative 0.0051 0.005 0.2744
Echinococcus granulosus kinase suppressor of Ras 1 0.0051 0.005 0.005
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Onchocerca volvulus 0.0768 0.2516 1
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Schistosoma mansoni ephrin receptor 0.0056 0.0067 0.0046
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis AGC family protein kinase 0.007 0.0116 0.0763
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0044 0.0026 0.017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Brugia malayi bone morphogenetic protein type 1 receptor 0.0051 0.005 0.0042
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus multilocularis Pleckstrin y 0.0044 0.0026 0.002
Echinococcus granulosus pdz domain containing protein 0.0044 0.0026 0.002
Leishmania major protein kinase, putative 0.0056 0.0067 0.4571
Echinococcus granulosus natriuretic peptide receptor 1 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0067 0.4571
Echinococcus granulosus tyrosine protein kinase shark 0.0051 0.005 0.005
Entamoeba histolytica receptor protein kinase, putative 0.0051 0.005 0.0166
Onchocerca volvulus 0.0051 0.005 0.0099
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0051 0.005 0.005
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0051 0.005 0.005
Echinococcus multilocularis calcium dependent secretion activator 1 0.0044 0.0026 0.002
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus tyrosine kinase 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus tyrosine protein kinase Srms 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.005 0.005
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0051 0.005 0.0042
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0044 0.0026 0.002
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.005 0.0332
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis protein kinase atn1, putative 0.0051 0.005 0.0332
Echinococcus granulosus cytohesin 1 0.0044 0.0026 0.002
Echinococcus multilocularis tyrosine protein kinase Srms 0.0051 0.005 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Loa Loa (eye worm) TK/Met protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Onchocerca volvulus 0.0051 0.005 0.0099
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Trypanosoma cruzi protein kinase, putative 0.0051 0.005 0.2744
Loa Loa (eye worm) hypothetical protein 0.0326 0.0997 0.099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.005 0.0029
Echinococcus multilocularis neuroglian 0.0113 0.0264 0.0306
Plasmodium vivax tyrosine kinase-like protein, putative 0.0051 0.005 0.2744
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0143 0.0367 0.2419
Echinococcus granulosus Regulator of G protein signaling 20 0.0477 0.1517 0.1806
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0051 0.005 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Onchocerca volvulus 0.0051 0.005 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus multilocularis semaphorin 5B 0.0326 0.0997 0.1184
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.005 0.0166
Plasmodium falciparum serine/threonine protein kinase, putative 0.007 0.0116 1
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus multilocularis Immunoglobulin 0.0113 0.0264 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Brugia malayi integrin-linked kinase 0.0051 0.005 0.0042
Entamoeba histolytica hypothetical protein 0.0143 0.0367 0.2288
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis protein tyrosine kinase 0.0051 0.005 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni centaurin alpha 0.0044 0.0026 0.0005
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0056 0.0067 0.4571
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0067 0.0276
Loa Loa (eye worm) AUR protein kinase 0.007 0.0116 0.0107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0118 0.0281 0.0272
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0051 0.005 0.0042
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0067 0.4571
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0044 0.0026 0.002
Echinococcus granulosus c src tyrosine kinase 0.0051 0.005 0.005
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0051 0.005 0.0029
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0051 0.005 0.005
Plasmodium falciparum tyrosine kinase-like protein 0.0051 0.005 0.2744
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus tyrosine protein kinase HCK 0.0051 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.005 0.0332
Echinococcus granulosus regulator of G protein signaling 7 0.0477 0.1517 0.1806
Loa Loa (eye worm) hypothetical protein 0.0477 0.1517 0.1509
Onchocerca volvulus 0.0326 0.0997 0.3902
Trichomonas vaginalis centaurin/arf, putative 0.0044 0.0026 0.017
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0051 0.005 0.0166
Toxoplasma gondii protein kinase 0.0051 0.005 0.2744
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Entamoeba histolytica protein kinase domain containing protein 0.0194 0.0542 0.3464
Echinococcus multilocularis raf serine:threonine protein kinase 0.0051 0.005 0.005
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.2465 0.8358 0.8357
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Brugia malayi Variant SH3 domain containing protein 0.0044 0.0026 0.0017
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0051 0.005 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Brugia malayi Uncoordinated protein 104 0.0044 0.0026 0.0017
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.005 0.005
Echinococcus granulosus neuroglian 0.0113 0.0264 0.0306
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0051 0.005 0.005
Entamoeba histolytica hypothetical protein 0.0143 0.0367 0.2288
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.005 0.0332
Echinococcus multilocularis cytohesin 1 0.0044 0.0026 0.002
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.005 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Entamoeba histolytica protein kinase, putative 0.0056 0.0067 0.0276
Schistosoma mansoni tyrosine protein kinase 0.0051 0.005 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0056 0.0067 0.4571
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0044 0.0026 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.005 0.0332
Loa Loa (eye worm) Plekhf2 protein 0.0044 0.0026 0.0017
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.005 0.0166
Echinococcus multilocularis Ras associated and pleckstrin y 0.0044 0.0026 0.002
Schistosoma mansoni regulator of G protein signaling 0.0477 0.1517 0.1499
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0056 0.0067 0.4571
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0051 0.005 0.0042
Echinococcus multilocularis beta 1 syntrophin 0.0044 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0113 0.0264 0.0256
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus granulosus pleckstrin y domain containing family A 0.0044 0.0026 0.002
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0044 0.0026 0.002
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Brugia malayi hypothetical protein 0.0477 0.1517 0.1509
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.007 0.0116 0.0603
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Entamoeba histolytica protein kinase, putative 0.0056 0.0067 0.0276
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0164 0.044 0.0431
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus multilocularis tyrosine protein kinase 0.0051 0.005 0.005
Plasmodium falciparum protein kinase, putative 0.0063 0.0092 0.7314
Loa Loa (eye worm) serine/threonine protein kinase 0.0051 0.005 0.0042
Onchocerca volvulus 0.0051 0.005 0.0099
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0367 0.2419
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.007 0.0116 0.0603
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus multilocularis actin binding protein anillin 0.0044 0.0026 0.002
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0044 0.0026 0.002
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.005 0.0166
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0056 0.0067 0.4571
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0051 0.005 0.005
Schistosoma mansoni axis inhibition protein axin 0.0477 0.1517 0.1499
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.005 0.005
Entamoeba histolytica receptor protein kinase, putative 0.0051 0.005 0.0166
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Schistosoma mansoni goodpasture antigen-binding protein 0.0044 0.0026 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0477 0.1517 1
Loa Loa (eye worm) TK/RYK protein kinase 0.0051 0.005 0.0042
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0056 0.0067 0.4571
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Plasmodium falciparum tyrosine kinase-like protein 0.0051 0.005 0.2744
Trichomonas vaginalis STE family protein kinase 0.0051 0.005 0.0332
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus multilocularis ephrin type A receptor 4 A 0.0051 0.005 0.005
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0477 0.1517 1
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0056 0.0067 0.007
Schistosoma mansoni serine/threonine protein kinase 0.2255 0.7636 0.7631
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0477 0.1517 0.1499
Leishmania major hypothetical protein, conserved 0.0051 0.005 0.2744
Loa Loa (eye worm) hypothetical protein 0.0118 0.0281 0.0272
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Brugia malayi Receptor family ligand binding region containing protein 0.0051 0.005 0.0042
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0367 0.2419
Trypanosoma cruzi Protein kinase B 0.0056 0.0067 0.4571
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2255 0.7636 0.7634
Brugia malayi hypothetical protein 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0044 0.0026 0.002
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0067 0.0276
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0143 0.0367 0.2419
Brugia malayi Raf kinase 0.0051 0.005 0.0042
Echinococcus granulosus Pleckstrin y 0.0044 0.0026 0.002
Echinococcus multilocularis pdz domain containing protein 0.0044 0.0026 0.002
Toxoplasma gondii protein kinase domain-containing protein 0.0051 0.005 0.2744
Echinococcus multilocularis integrin linked protein kinase 0.0051 0.005 0.005
Brugia malayi Regulator of G protein signaling domain containing protein 0.0477 0.1517 0.1509
Brugia malayi hypothetical protein 0.0118 0.0281 0.0272
Schistosoma mansoni serine/threonine-protein kinase 0.0056 0.0067 0.0046
Brugia malayi C-terminal src kinase protein 1 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein kinase domain containing protein 0.007 0.0116 0.0603
Leishmania major protein kinase, putative 0.007 0.0116 1
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0067 0.0276
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Schistosoma mansoni protein kinase 0.007 0.0116 0.0095
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.005 0.005
Echinococcus granulosus beta-adrenergic receptor kinase 0.2255 0.7636 0.9135
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Brugia malayi SH2 domain containing protein 0.0051 0.005 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Schistosoma mansoni syntrophin 0.0044 0.0026 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus oxysterol binding protein 1 0.0044 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0113 0.0264 0.0256
Echinococcus granulosus raf serine:threonine protein kinase 0.0051 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0113 0.0264 0.0244
Schistosoma mansoni hypothetical protein 0.0326 0.0997 0.0978
Schistosoma mansoni serine/threonine-protein kinase 0.0056 0.0067 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Schistosoma mansoni protein tyrosine kinase 0.0051 0.005 0.0029
Schistosoma mansoni vav2 0.0044 0.0026 0.0005
Echinococcus granulosus tyrosine protein kinase Src64B 0.0051 0.005 0.005
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0056 0.0067 0.4571
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Schistosoma mansoni zinc finger protein 0.0044 0.0026 0.0005
Leishmania major protein kinase, putative 0.0056 0.0067 0.4571
Echinococcus granulosus exocyst complex component 2 0.0143 0.0367 0.0429
Echinococcus granulosus transcription factor collier 0.0143 0.0367 0.0429
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0056 0.0067 0.4571
Echinococcus multilocularis protein kinase 0.0051 0.005 0.005
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus multilocularis axis inhibition protein axin 0.0477 0.1517 0.1806
Echinococcus granulosus plexin a4 0.091 0.3008 0.3592
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0051 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Brugia malayi Dynamin 0.0044 0.0026 0.0017
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0051 0.005 0.0099
Entamoeba histolytica tyrosin kinase, putative 0.0194 0.0542 0.3464
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Trichomonas vaginalis alpha chimerin, putative 0.0044 0.0026 0.017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0051 0.005 0.0029
Brugia malayi MAX-1A 0.0044 0.0026 0.0017
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.005 0.0042
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0051 0.005 0.005
Schistosoma mansoni fibrocystin l 0.0143 0.0367 0.0347
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0044 0.0026 0.0005
Toxoplasma gondii protein kinase domain-containing protein 0.0056 0.0067 0.4571
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0056 0.0067 0.4571
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Schistosoma mansoni serine/threonine RGC 0.0051 0.005 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Brugia malayi hypothetical protein 0.0477 0.1517 0.1509
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Entamoeba histolytica p21-activated kinase 0.0056 0.0067 0.0276
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0051 0.005 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Schistosoma mansoni regulator of G protein signaling 0.0477 0.1517 0.1499
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.007 0.0116 0.0128
Brugia malayi Plekhf2 protein 0.0044 0.0026 0.0017
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0051 0.005 0.005
Loa Loa (eye worm) TK/ALK protein kinase 0.0283 0.085 0.0842
Trichomonas vaginalis conserved hypothetical protein 0.0477 0.1517 1
Schistosoma mansoni hypothetical protein 0.0326 0.0997 0.0978
Loa Loa (eye worm) hypothetical protein 0.0477 0.1517 0.1509
Schistosoma mansoni axis inhibition protein axin 0.0477 0.1517 0.1499
Brugia malayi Tyrosine-protein kinase PR2 0.0051 0.005 0.0042
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0118 0.0281 0.0272
Brugia malayi Furin-like cysteine rich region family protein 0.0051 0.005 0.0042
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0051 0.005 0.0042
Schistosoma mansoni plexin 0.0768 0.2516 0.2501
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Echinococcus granulosus fibroblast growth factor receptor 4 0.0051 0.005 0.005
Loa Loa (eye worm) TK/ACK protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni hypothetical protein 0.0143 0.0367 0.0347
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Brugia malayi TBC domain containing protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0044 0.0026 0.0017
Echinococcus granulosus regulator of G protein signaling 3 0.0477 0.1517 0.1806
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus multilocularis DCC interacting protein 13 beta 0.0044 0.0026 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0056 0.0067 0.4571
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.2465 0.8358 0.8357
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0051 0.005 0.005
Trypanosoma brucei protein kinase, putative 0.0056 0.0067 0.4571
Echinococcus granulosus dynamin 1 0.0044 0.0026 0.002
Echinococcus granulosus GRB2 associated binding protein 3 0.0044 0.0026 0.002
Entamoeba histolytica hypothetical protein 0.0056 0.0067 0.0276
Schistosoma mansoni hypothetical protein 0.0051 0.005 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.2465 0.8358 0.8357
Onchocerca volvulus 0.0051 0.005 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.005 0.0029
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Brugia malayi Oxysterol binding protein 0.0044 0.0026 0.0017
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.005 0.005
Brugia malayi Tyrosine-protein kinase abl-1 0.0051 0.005 0.0042
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0051 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0005
Trypanosoma brucei aurora B kinase 0.007 0.0116 1
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Plasmodium vivax tyrosine kinase-like protein, putative 0.0051 0.005 0.2744
Schistosoma mansoni nephrin 0.0118 0.0281 0.026
Echinococcus granulosus myotubularin protein 13 0.0044 0.0026 0.002
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0056 0.0067 0.007
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0044 0.0026 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Brugia malayi DNA-binding protein LAG-1 0.0143 0.0367 0.0358
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0051 0.005 0.005
Onchocerca volvulus 0.0051 0.005 0.0099
Echinococcus multilocularis epidermal growth factor receptor 0.0051 0.005 0.005
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0051 0.005 0.0332
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0044 0.0026 0.017
Onchocerca volvulus 0.0051 0.005 0.0099
Leishmania major serine/threonine-protein kinase a, putative 0.0056 0.0067 0.4571
Brugia malayi Guanylyl cyclase protein 23 0.0051 0.005 0.0042
Schistosoma mansoni vesicular amine transporter 0.0116 0.0273 0.0253
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis regulator of G protein signaling 7 0.0477 0.1517 0.1806
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Echinococcus granulosus regulator of G protein signaling 7 0.0477 0.1517 0.1806
Echinococcus granulosus tyrosine protein kinase pr2 0.0051 0.005 0.005
Echinococcus multilocularis Oxysterol binding protein 11 0.0044 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0326 0.0997 0.099
Echinococcus granulosus activin receptor type 0.0063 0.0092 0.0099
Echinococcus granulosus beta 1 syntrophin 0.0044 0.0026 0.002
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.005 0.0029
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.005 0.0166
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Echinococcus granulosus Oxysterol binding protein 11 0.0044 0.0026 0.002
Echinococcus multilocularis roundabout 2 0.0118 0.0281 0.0326
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Brugia malayi serine/threonine protein kinase 6 0.007 0.0116 0.0107
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0056 0.0067 0.4571
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0367 0.2419
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.005 0.0166
Trichomonas vaginalis protein tyrosine kinase, putative 0.0051 0.005 0.0332
Brugia malayi plexin A 0.091 0.3008 0.3002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Echinococcus multilocularis Rho GTPase activating protein 24 0.0044 0.0026 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Entamoeba histolytica cell surface protease gp63, putative 0.0143 0.0367 0.2288
Schistosoma mansoni hypothetical protein 0.0441 0.1394 0.1376
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Brugia malayi Oxysterol-binding protein 0.0044 0.0026 0.0017
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0051 0.005 0.005
Echinococcus multilocularis c src tyrosine kinase 0.0051 0.005 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Echinococcus multilocularis activated cdc42 kinase 1 0.0051 0.005 0.005
Entamoeba histolytica protein kinase, putative 0.007 0.0116 0.0603
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0051 0.005 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Brugia malayi serine/threonine-protein kinase 6 0.007 0.0116 0.0107
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0051 0.005 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.044 0.0431
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Trypanosoma brucei protein kinase, putative 0.0063 0.0092 0.7314
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0477 0.1517 0.1509
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0051 0.005 0.005
Schistosoma mansoni regulator of G protein signaling 0.0477 0.1517 0.1499
Plasmodium falciparum protein kinase, putative 0.0051 0.005 0.2744
Brugia malayi Probable exocyst complex component Sec5 0.0143 0.0367 0.0358
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Brugia malayi Pleckstrin Homology Domain 0.0044 0.0026 0.0017
Echinococcus multilocularis insulin receptor 0.0051 0.005 0.005
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.007 0.0116 0.0603
Echinococcus granulosus calcium dependent secretion activator 1 0.0044 0.0026 0.002
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Loa Loa (eye worm) PH domain-containing protein 0.0044 0.0026 0.0017
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0044 0.0026 0.017
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus multilocularis kinase suppressor of Ras 1 0.0051 0.005 0.005
Brugia malayi Cytohesin 3 0.0044 0.0026 0.0017
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0044 0.0026 0.0005
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Echinococcus multilocularis tyrosine protein kinase HCK 0.0051 0.005 0.005
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0067 0.4571
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0051 0.005 0.0042
Loa Loa (eye worm) sema domain-containing protein 0.0326 0.0997 0.099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica ankyrin repeat protein 0.0051 0.005 0.0166
Echinococcus multilocularis G protein coupled receptor kinase 6 0.2465 0.8358 1
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trypanosoma brucei Pseudokinase, putative 0.0051 0.005 0.2744
Echinococcus multilocularis myotubularin protein 13 0.0044 0.0026 0.002
Onchocerca volvulus 0.0051 0.005 0.0099
Echinococcus multilocularis protein KINase family member (kin 25) 0.0051 0.005 0.005
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0051 0.005 0.0042
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0067 0.4571
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0044 0.0026 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.005 0.0042
Entamoeba histolytica hypothetical protein 0.0477 0.1517 1
Loa Loa (eye worm) AUR protein kinase 0.007 0.0116 0.0107
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0051 0.005 0.2744
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0067 0.4571
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0367 0.2419
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Entamoeba histolytica hypothetical protein 0.0477 0.1517 1
Echinococcus granulosus activated cdc42 kinase 1 0.0051 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Echinococcus granulosus Rho GTPase activating protein 24 0.0044 0.0026 0.002
Loa Loa (eye worm) AGC/AKT protein kinase 0.0056 0.0067 0.0058
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Trypanosoma brucei Flagellum attachment zone protein 20 0.0051 0.005 0.2744
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Echinococcus multilocularis hypothetical protein 0.0326 0.0997 0.1184
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0477 0.1517 0.1806
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis protein transport protein sec7, putative 0.0044 0.0026 0.017
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0477 0.1517 0.1509
Echinococcus granulosus tyrosine kinase 0.0051 0.005 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis tyrosine protein kinase pr2 0.0051 0.005 0.005
Echinococcus multilocularis expressed protein 0.0477 0.1517 0.1806
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0044 0.0026 0.017
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0056 0.0067 0.4571
Toxoplasma gondii STE kinase 0.0051 0.005 0.2744
Loa Loa (eye worm) rho-GTPase-activating 0.0044 0.0026 0.0017
Loa Loa (eye worm) oxysterol binding protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Schistosoma mansoni myotubularin-related protein 0.0044 0.0026 0.0005
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0063 0.0092 0.7314
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0051 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0143 0.0367 0.0358
Echinococcus multilocularis Regulator of G protein signaling 20 0.0477 0.1517 0.1806
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.005 0.005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0367 0.2419
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Brugia malayi hypothetical protein 0.0044 0.0026 0.0017
Leishmania major protein kinase, putative 0.0063 0.0092 0.7314
Schistosoma mansoni goodpasture antigen-binding protein 0.0044 0.0026 0.0005
Brugia malayi Variant SH3 domain containing protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0044 0.0026 0.0017
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0044 0.0026 0.002
Echinococcus granulosus defective proboscis extension response 0.0113 0.0264 0.0306
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0326 0.0997 0.099
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus multilocularis dynamin 1 0.0044 0.0026 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0477 0.1517 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Echinococcus granulosus serine:threonine protein kinase 12 B 0.007 0.0116 0.0128
Echinococcus granulosus Immunoglobulin 0.0113 0.0264 0.0306
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis receptor type guanylyl cyclase 0.0051 0.005 0.005
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0113 0.0264 0.0306
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0051 0.005 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0051 0.005 0.0332
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Brugia malayi A-kinase anchor protein 10, precursor 0.0477 0.1517 0.1509
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0051 0.005 0.0042
Echinococcus granulosus Pleckstrin y 0.0044 0.0026 0.002
Leishmania major folate/biopterin transporter, putative 0.0056 0.0067 0.4571
Echinococcus granulosus tyrosine protein kinase Blk 0.0051 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Brugia malayi Sema domain containing protein 0.0326 0.0997 0.099
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0051 0.005 0.005
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0051 0.005 0.005
Echinococcus multilocularis oxysterol binding protein 3 0.0044 0.0026 0.002
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0051 0.005 0.0042
Loa Loa (eye worm) protein kinase domain-containing protein 0.0051 0.005 0.0042
Schistosoma mansoni protein kinase 0.0063 0.0092 0.0071
Loa Loa (eye worm) PXA domain-containing protein 0.0477 0.1517 0.1509
Loa Loa (eye worm) plexin A 0.091 0.3008 0.3002
Echinococcus granulosus integrin linked protein kinase 0.0051 0.005 0.005
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0044 0.0026 0.002
Loa Loa (eye worm) hypothetical protein 0.0143 0.0367 0.0358
Entamoeba histolytica protein kinase, putative 0.0056 0.0067 0.0276
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0143 0.0367 0.2419
Trichomonas vaginalis AGC family protein kinase 0.007 0.0116 0.0763
Entamoeba histolytica protein kinase, putative 0.0056 0.0067 0.0276
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0051 0.005 0.2744
Schistosoma mansoni regulator of G protein signaling 0.0477 0.1517 0.1499
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.005 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Brugia malayi Plexin repeat family protein 0.0768 0.2516 0.251
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0056 0.0067 0.0441
Brugia malayi IPT/TIG domain containing protein 0.0143 0.0367 0.0358
Echinococcus multilocularis natriuretic peptide receptor 1 0.0051 0.005 0.005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0051 0.005 0.0029
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.2465 0.8358 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0051 0.005 0.005
Echinococcus multilocularis pleckstrin y domain containing family A 0.0044 0.0026 0.002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0044 0.0026 0.002
Brugia malayi regulator of G-protein signaling rgs-7 0.0477 0.1517 0.1509
Loa Loa (eye worm) hypothetical protein 0.0143 0.0367 0.0358
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.005 0.0042
Onchocerca volvulus 0.0051 0.005 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis plexin a4 0.091 0.3008 0.3592
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0063 0.0092 0.0099
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0005
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Brugia malayi Dynamin 0.0044 0.0026 0.0017
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0113 0.0264 0.0244
Onchocerca volvulus 0.0051 0.005 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Echinococcus multilocularis tyrosine kinase 0.0051 0.005 0.005
Schistosoma mansoni regulator of G protein signaling 0.0477 0.1517 0.1499
Echinococcus granulosus aurora kinase A 0.007 0.0116 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0477 0.1517 1
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus granulosus semaphorin 1A 0.0326 0.0997 0.1184
Loa Loa (eye worm) hypothetical protein 0.0326 0.0997 0.099
Brugia malayi Protein kinase domain containing protein 0.0283 0.085 0.0842
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0063 0.0092 0.7314
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni oxysterol-binding protein 1 0.0044 0.0026 0.0005
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0067 0.0276
Schistosoma mansoni z-protein (S1r protein) 0.0477 0.1517 0.1499
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Echinococcus multilocularis tyrosine protein kinase shark 0.0051 0.005 0.005
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0051 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.2255 0.7636 0.7631
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus granulosus G protein coupled receptor kinase 1 0.1778 0.5995 0.7169
Loa Loa (eye worm) sema domain-containing protein 0.0326 0.0997 0.099
Brugia malayi hypothetical protein 0.0326 0.0997 0.099
Entamoeba histolytica protein kinase domain containing protein 0.0063 0.0092 0.0441
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.005 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0477 0.1517 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.005 0.005
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Echinococcus multilocularis GRB2 associated binding protein 3 0.0044 0.0026 0.002
Loa Loa (eye worm) TK/INSR protein kinase 0.0051 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0143 0.0367 0.0358
Brugia malayi SRC-1 0.0051 0.005 0.0042
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Echinococcus granulosus regulator of G protein signaling 3 0.0477 0.1517 0.1806
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Trypanosoma cruzi protein kinase, putative 0.0051 0.005 0.2744
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus multilocularis regulator of G protein signaling 7 0.0477 0.1517 0.1806
Brugia malayi hypothetical protein 0.0051 0.005 0.0042
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica serine/threonine kinase, putative 0.0051 0.005 0.0166
Echinococcus granulosus expressed protein 0.0477 0.1517 0.1806
Entamoeba histolytica hypothetical protein, conserved 0.0051 0.005 0.0166
Schistosoma mansoni plexin 0.0441 0.1394 0.1376
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0051 0.005 0.0029
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0113 0.0264 0.0306
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Brugia malayi Fibronectin type III domain containing protein 0.0118 0.0281 0.0272
Brugia malayi serine/threonine kinase 12 0.007 0.0116 0.0107
Echinococcus multilocularis heat shock protein 70 0.0051 0.005 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Schistosoma mansoni protein kinase 0.0063 0.0092 0.0071
Schistosoma mansoni growth factor receptor-bound protein 0.0044 0.0026 0.0005
Loa Loa (eye worm) hypothetical protein 0.0768 0.2516 0.251
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Brugia malayi regulator of G-protein signaling egl-10 0.0477 0.1517 0.1509
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0051 0.005 0.005
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0204 0.0579 0.057
Trichomonas vaginalis centaurin alpha, putative 0.0044 0.0026 0.017
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Trichomonas vaginalis hypothetical protein 0.0044 0.0026 0.017
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0051 0.005 0.2744
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus granulosus semaphorin 5B 0.0326 0.0997 0.1184
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0005
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0063 0.0092 0.7314
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus granulosus protein kinase 0.0051 0.005 0.005
Schistosoma mansoni cell adhesion molecule 0.0118 0.0281 0.026
Echinococcus granulosus retinal guanylyl cyclase 2 0.0051 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0477 0.1517 0.1806
Entamoeba histolytica cysteine surface protein, putative 0.0051 0.005 0.0166
Echinococcus multilocularis FL cytokine receptor 0.0051 0.005 0.005
Echinococcus granulosus protein tyrosine kinase 0.0051 0.005 0.005
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0044 0.0026 0.017
Trichomonas vaginalis AGC family protein kinase 0.007 0.0116 0.0763
Plasmodium falciparum protein kinase, putative 0.0051 0.005 0.2744
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Entamoeba histolytica protein kinase, putative 0.0056 0.0067 0.0276
Echinococcus multilocularis tyrosine protein kinase Abl 0.0051 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0477 0.1517 0.1509
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Entamoeba histolytica hypothetical protein 0.0477 0.1517 1
Brugia malayi Cadps2 protein 0.0044 0.0026 0.0017
Echinococcus multilocularis Pleckstrin y 0.0044 0.0026 0.002
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0051 0.005 0.0029
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0067 0.0276
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0042
Echinococcus multilocularis beta adrenergic receptor kinase 0.2255 0.7636 0.9135
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Schistosoma mansoni semaphorin 5-related 0.0326 0.0997 0.0978
Echinococcus multilocularis transcription factor collier 0.0143 0.0367 0.0429
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0044 0.0026 0.002
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0056 0.0067 0.0441
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Loa Loa (eye worm) uncoordinated protein 104 0.0044 0.0026 0.0017
Entamoeba histolytica protein kinase, putative 0.0051 0.005 0.0166
Entamoeba histolytica protein kinase , putative 0.007 0.0116 0.0603
Schistosoma mansoni dynamin 0.0044 0.0026 0.0005
Loa Loa (eye worm) TK/CSK protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Onchocerca volvulus 0.0051 0.005 0.0099
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Echinococcus granulosus axis inhibition protein axin 0.0477 0.1517 0.1806
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0143 0.0367 0.2419
Loa Loa (eye worm) TK protein kinase 0.0051 0.005 0.0042
Echinococcus multilocularis activin receptor type 0.0063 0.0092 0.0099
Entamoeba histolytica protein kinase, putative 0.0056 0.0067 0.0276
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0051 0.005 0.005
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0051 0.005 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0116 0.0095
Echinococcus granulosus Pleckstrin y 0.0044 0.0026 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0044 0.0026 0.0005
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Brugia malayi PXA domain containing protein 0.0477 0.1517 0.1509
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Onchocerca volvulus Tyrosine kinase homolog 0.0051 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0477 0.1517 0.1509
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0026 0.017
Echinococcus granulosus axis inhibition protein axin 0.0477 0.1517 0.1806
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Entamoeba histolytica protein kinase, putative 0.0056 0.0067 0.0276
Loa Loa (eye worm) hypothetical protein 0.0326 0.0997 0.099
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.005 0.0332
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus granulosus activated cdc42 kinase 1 0.0051 0.005 0.005
Trichomonas vaginalis centaurin gamma, putative 0.0044 0.0026 0.017
Entamoeba histolytica hypothetical protein 0.0143 0.0367 0.2288
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0051 0.005 0.005
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Trypanosoma brucei rac serine-threonine kinase, putative 0.0056 0.0067 0.4571
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Toxoplasma gondii aurora kinase 0.007 0.0116 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Echinococcus multilocularis regulator of G protein signaling 3 0.0477 0.1517 0.1806
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0044 0.0026 0.002
Loa Loa (eye worm) TK/EGFR protein kinase 0.0051 0.005 0.0042
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0056 0.0067 0.4571
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Echinococcus multilocularis oxysterol binding protein 9 0.0044 0.0026 0.002
Echinococcus multilocularis regulator of G protein signaling 3 0.0477 0.1517 0.1806
Echinococcus granulosus ephrin type A receptor 4 A 0.0051 0.005 0.005
Brugia malayi PXA domain containing protein 0.0477 0.1517 0.1509
Schistosoma mansoni protein kinase 0.0051 0.005 0.0029
Entamoeba histolytica tyrosin kinase, putative 0.0051 0.005 0.0166
Brugia malayi Sema domain containing protein 0.0326 0.0997 0.099
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0063 0.0092 0.7314
Schistosoma mansoni oxysterol-binding protein 1 0.0044 0.0026 0.0005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0026 0.0017
Brugia malayi ephrin receptor 1 precursor 0.0051 0.005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0477 0.1517 0.1509
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus granulosus tyrosine protein kinase Lyn 0.0063 0.0092 0.0099
Schistosoma mansoni dynamin 0.0044 0.0026 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0051 0.005 0.0166
Entamoeba histolytica ankyrin repeat protein 0.0051 0.005 0.0166
Trichomonas vaginalis AGC family protein kinase 0.007 0.0116 0.0763
Loa Loa (eye worm) hypothetical protein 0.0118 0.0281 0.0272
Loa Loa (eye worm) syntrophin-1 0.0044 0.0026 0.0017
Brugia malayi protein-tyrosine kinase 0.0051 0.005 0.0042
Loa Loa (eye worm) RGC/RGC protein kinase 0.0051 0.005 0.0042
Echinococcus granulosus oxysterol binding protein 9 0.0044 0.0026 0.002
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0051 0.005 0.005
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0051 0.005 0.0332
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0044 0.0026 0.002
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0063 0.0092 0.0099
Schistosoma mansoni ephrin receptor 0.0051 0.005 0.0029
Schistosoma mansoni tyrosine kinase 0.0051 0.005 0.0029
Echinococcus multilocularis axis inhibition protein axin 0.0477 0.1517 0.1806
Onchocerca volvulus 0.0051 0.005 0.0099
Loa Loa (eye worm) hypothetical protein 0.0441 0.1394 0.1386
Schistosoma mansoni zinc finger protein 0.0044 0.0026 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0051 0.005 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0477 0.1517 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0051 0.005 0.005
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Brugia malayi hypothetical protein 0.0326 0.0997 0.099
Echinococcus granulosus receptor type guanylyl cyclase 0.0051 0.005 0.005
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0044 0.0026 0.002
Loa Loa (eye worm) SRC-1 0.0051 0.005 0.0042
Brugia malayi hypothetical protein 0.0051 0.005 0.0042
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Brugia malayi PH domain containing protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) AUR protein kinase 0.007 0.0116 0.0107
Brugia malayi Protein kinase domain containing protein 0.0051 0.005 0.0042
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0044 0.0026 0.002
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0051 0.005 0.005
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0044 0.0026 0.0017
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0051 0.005 0.0042
Echinococcus multilocularis tyrosine protein kinase csk 0.0051 0.005 0.005
Echinococcus granulosus tyrosine protein kinase csk 0.0051 0.005 0.005
Brugia malayi Protein kinase domain containing protein 0.0056 0.0067 0.0058
Echinococcus granulosus roundabout 2 0.0118 0.0281 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.0367 0.2419
Entamoeba histolytica hypothetical protein 0.0051 0.005 0.0166
Loa Loa (eye worm) hypothetical protein 0.0113 0.0264 0.0256
Echinococcus multilocularis protein kinase 0.0051 0.005 0.005
Trichomonas vaginalis TKL family protein kinase 0.0051 0.005 0.0332
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0051 0.005 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0067 0.0441
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0051 0.005 0.005
Echinococcus granulosus DCC interacting protein 13 beta 0.0044 0.0026 0.002
Echinococcus multilocularis tyrosine kinase 0.0051 0.005 0.005
Echinococcus multilocularis transfer RNA-Thr 0.0051 0.005 0.005
Brugia malayi Syntrophin-1 0.0044 0.0026 0.0017

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 100 um PUBCHEM_BIOASSAY: GAPDH Dose Response Colorimetric Assay. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (binding) > 100 uM PUBCHEM_BIOASSAY: SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1548, AID1574, AID1577, AID1659, AID518] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.