TDR Targets

Basic information

Technical information

TDR Targets ID: 1427908
Name: 2-(phenoxy)-8-(thiophen-2-ylmethyl)pteridin-7 -one
MW: 336.368 | Formula: C17H12N4O2S
H donors: 0 H acceptors: 3 LogP: 2.58 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: O=c1cnc2c(n1Cc1cccs1)nc(nc2)Oc1ccccc1
InChi: 1S/C17H12N4O2S/c22-15-10-18-14-9-19-17(23-12-5-2-1-3-6-12)20-16(14)21(15)11-13-7-4-8-24-13/h1-10H,11H2
InChiKey: AGAINYKORDFPCM-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

2-(phenoxy)-8-(2-thienylmethyl)pteridin-7-one
2-(phenoxy)-8-(2-thienylmethyl)-7-pteridinone
NCGC00010669
PCOP-222453

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	cytochrome P450, family 3, subfamily A, polypeptide 4	Starlite/ChEMBL	No references
Homo sapiens	thyroid stimulating hormone receptor	Starlite/ChEMBL	No references
Homo sapiens	ubiquitin specific peptidase 2	Starlite/ChEMBL	No references
Homo sapiens	cytochrome P450, family 1, subfamily A, polypeptide 2	Starlite/ChEMBL	No references
Homo sapiens	cytochrome P450, family 2, subfamily C, polypeptide 19	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Trypanosoma brucei gambiense	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	Get druggable targets OG5_127431	All targets in OG5_127431
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	Get druggable targets OG5_127431	All targets in OG5_127431
Echinococcus multilocularis	ubiquitin specific protease 41	Get druggable targets OG5_127431	All targets in OG5_127431
Loa Loa (eye worm)	CYP4Cod1	Get druggable targets OG5_126554	All targets in OG5_126554
Schistosoma japonicum	IPR015063,Domain of unknown function DUF1873,domain-containing	Get druggable targets OG5_127431	All targets in OG5_127431
Brugia malayi	Cytochrome P450 family protein	Get druggable targets OG5_126582	All targets in OG5_126582
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	Get druggable targets OG5_127431	All targets in OG5_127431
Trichomonas vaginalis	conserved hypothetical protein	Get druggable targets OG5_127431	All targets in OG5_127431
Schistosoma japonicum	hypothetical protein	Get druggable targets OG5_127431	All targets in OG5_127431
Loa Loa (eye worm)	cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	Get druggable targets OG5_126554	All targets in OG5_126554
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	Get druggable targets OG5_127431	All targets in OG5_127431
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127431	All targets in OG5_127431
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	Get druggable targets OG5_127431	All targets in OG5_127431
Candida albicans	closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA	Get druggable targets OG5_126554	All targets in OG5_126554
Schistosoma japonicum	Ubiquitin carboxyl-terminal hydrolase 8, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Schistosoma japonicum	IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing	Get druggable targets OG5_127431	All targets in OG5_127431
Loa Loa (eye worm)	cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	Get druggable targets OG5_127431	All targets in OG5_127431
Echinococcus granulosus	ubiquitin specific protease 41	Get druggable targets OG5_127431	All targets in OG5_127431
Brugia malayi	Cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Trypanosoma brucei gambiense	ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Leishmania mexicana	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Candida albicans	similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11	Get druggable targets OG5_126554	All targets in OG5_126554
Schistosoma japonicum	expressed protein	Get druggable targets OG5_127431	All targets in OG5_127431
Leishmania braziliensis	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Trypanosoma congolense	ubiquitin carboxyl-terminal hydrolase, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Leishmania mexicana	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Cryptosporidium parvum	ubiquitin C-terminal hydrolase of the cysteine proteinase fold	Get druggable targets OG5_127431	All targets in OG5_127431
Leishmania braziliensis	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Leishmania infantum	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Candida albicans	cytochrome P450 556	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126554	All targets in OG5_126554
Schistosoma japonicum	ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative	Get druggable targets OG5_127431	All targets in OG5_127431
Trypanosoma cruzi	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Candida albicans	cytochrome P450 56	Get druggable targets OG5_126554	All targets in OG5_126554
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Cryptosporidium hominis	ubiquitin specific protease 66	Get druggable targets OG5_127431	All targets in OG5_127431
Trypanosoma congolense	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Brugia malayi	Cytochrome P450 family protein	Get druggable targets OG5_126554	All targets in OG5_126554
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	Get druggable targets OG5_127431	All targets in OG5_127431
Leishmania donovani	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Loa Loa (eye worm)	follicle stimulating hormone receptor	Get druggable targets OG5_130089	All targets in OG5_130089
Trypanosoma cruzi	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania infantum	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Candida albicans	similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania major	cytochrome p450-like protein	Get druggable targets OG5_126554	All targets in OG5_126554
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	Get druggable targets OG5_127431	All targets in OG5_127431
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	Get druggable targets OG5_127431	All targets in OG5_127431
Schistosoma japonicum	Ubiquitin carboxyl-terminal hydrolase 8, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Trypanosoma brucei	cytochrome P450, putative	Get druggable targets OG5_126554	All targets in OG5_126554
Leishmania donovani	ubiquitin carboxyl-terminal hydrolase, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Brugia malayi	follicle stimulating hormone receptor	Get druggable targets OG5_130089	All targets in OG5_130089
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	Get druggable targets OG5_127431	All targets in OG5_127431
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	Get druggable targets OG5_127431	All targets in OG5_127431
Candida albicans	ubiquitin-specific protease	Get druggable targets OG5_127431	All targets in OG5_127431
Loa Loa (eye worm)	cytochrome P450 family protein	Get druggable targets OG5_126582	All targets in OG5_126582
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	Get druggable targets OG5_127431	All targets in OG5_127431

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Plasmodium falciparum	ubiquitin specific protease, putative	ubiquitin specific peptidase 2	362 aa	378 aa	25.7 %
Brugia malayi	cytochrome P450	cytochrome P450, family 3, subfamily A, polypeptide 4	502 aa	492 aa	24.2 %
Brugia malayi	Cytochrome P450 family protein	cytochrome P450, family 1, subfamily A, polypeptide 2	516 aa	470 aa	26.2 %
Leishmania major	cytochrome p450-like protein	cytochrome P450, family 2, subfamily C, polypeptide 19	490 aa	411 aa	23.1 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus		0.0043	0.0307	0.05
Trypanosoma cruzi	PAB1-binding protein , putative	0.005	0.0387	0.1201
Brugia malayi	Bromodomain associated family protein	0.0018	0.0024	0.0032
Echinococcus multilocularis	geminin	0.0177	0.1825	0.2505
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0057	0.0462	0.1437
Schistosoma mansoni	Protein aveugle	0.0026	0.0118	0.0112
Trypanosoma cruzi	hypothetical protein	0.0026	0.0118	0.0352
Mycobacterium tuberculosis	Inositol-1-monophosphatase SuhB	0.0033	0.0193	0.0251
Trypanosoma brucei	importin beta-1 subunit, putative	0.0062	0.052	0.1619
Toxoplasma gondii	PHD-finger domain-containing protein	0.0018	0.0024	0.0095
Toxoplasma gondii	PLU-1 family protein	0.0046	0.0337	0.173
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.005	0.0388	0.0685
Loa Loa (eye worm)	tnks protein	0.0026	0.0118	0.0154
Plasmodium falciparum	ataxin-2 like protein, putative	0.005	0.0387	0.7325
Echinococcus granulosus	PHD finger protein 14	0.0018	0.0024	0.0025
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.002	0.0052	0.0063
Echinococcus multilocularis	suppression of tumorigenicity 18 protein	0.0099	0.0945	0.1293
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0225	0.2363	0.4116
Echinococcus granulosus	sphingomyelin synthase protein 1	0.0026	0.0118	0.0154
Onchocerca volvulus		0.0027	0.0125	0.0178
Echinococcus multilocularis	jumonji domain containing protein	0.004	0.0273	0.0367
Brugia malayi	Shank2E	0.0026	0.0118	0.0197
Echinococcus granulosus	importin subunit beta 1	0.0062	0.052	0.0707
Brugia malayi	beta-lactamase family protein	0.0035	0.022	0.0378
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Loa Loa (eye worm)	hypothetical protein	0.0474	0.5179	0.7125
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0027	0.0125	0.0163
Loa Loa (eye worm)	MBCTL1	0.0099	0.0945	0.1293
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0093	0.0872	0.1193
Loa Loa (eye worm)	PHD-finger family protein	0.0018	0.0024	0.0025
Echinococcus granulosus	peregrin	0.0029	0.0146	0.0192
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0057	0.0462	0.1437
Mycobacterium leprae	Probable lipase LipE	0.0035	0.022	0.0049
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0093	0.0872	0.0866
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0057	0.0462	0.0628
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Brugia malayi	coiled-coil like protein 1	0.0026	0.0118	0.0197
Giardia lamblia	PHD finger protein 15	0.0029	0.0146	0.0167
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0052	0.0145
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0353	0.0477
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0125	0.0163
Schistosoma mansoni	PHD zinc finger protein XAP135-related	0.0018	0.0024	0.0018
Loa Loa (eye worm)	inositol-1	0.0037	0.0237	0.0317
Loa Loa (eye worm)	hypothetical protein	0.002	0.0052	0.0063
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0093	0.0872	0.0866
Trypanosoma brucei	unspecified product	0.002	0.0052	0.0145
Schistosoma mansoni	sex comb on midleg homolog	0.0276	0.2936	0.2931
Onchocerca volvulus		0.0035	0.022	0.0347
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Brugia malayi	follicle stimulating hormone receptor	0.0282	0.3006	0.5301
Plasmodium vivax	hypothetical protein, conserved	0.0029	0.0146	0.2453
Echinococcus granulosus	geminin	0.0177	0.1825	0.2505
Onchocerca volvulus		0.0313	0.3358	0.5909
Schistosoma mansoni	phd finger protein	0.0044	0.032	0.0314
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0172	0.0166
Trichomonas vaginalis	peptide N-glycanase, putative	0.0518	0.5665	1
Mycobacterium ulcerans	esterase/lipase LipP	0.0035	0.022	0.0299
Plasmodium falciparum	JmjC domain-containing protein, putative	0.0039	0.0268	0.4908
Echinococcus multilocularis	dnaJ subfamily B	0.0445	0.4841	0.666
Loa Loa (eye worm)	beta-lactamase	0.0035	0.022	0.0294
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Echinococcus multilocularis	tar DNA binding protein	0.0065	0.056	0.0763
Schistosoma mansoni	polyhomeotic	0.0026	0.0118	0.0112
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0031	0.0172	0.0228
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Echinococcus multilocularis	Sterile alpha motif SAM	0.0026	0.0118	0.0154
Echinococcus multilocularis	zinc finger protein	0.0018	0.0024	0.0025
Schistosoma mansoni	lip-related protein (liprin) alpha	0.0026	0.0118	0.0112
Plasmodium vivax	JmjC domain containing protein	0.0039	0.0268	0.4908
Echinococcus multilocularis	phd finger protein 12	0.0018	0.0024	0.0025
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0282	0.3006	0.4132
Brugia malayi	sterile alpha and TIR motif containing protein 1 isoform a	0.0026	0.0118	0.0197
Schistosoma mansoni	cpg binding protein	0.0049	0.0377	0.0371
Echinococcus multilocularis	lysine specific demethylase 5A	0.0115	0.1122	0.1537
Toxoplasma gondii	LsmAD domain-containing protein	0.005	0.0387	0.1992
Entamoeba histolytica	deoxycytidyl transferase, putative	0.002	0.0052	0.0067
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0157	0.159	0.2739
Toxoplasma gondii	histone lysine methyltransferase SET1	0.006	0.0503	0.2595
Echinococcus granulosus	dnaJ subfamily B	0.0445	0.4841	0.666
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0045	0.0327	0.0576
Brugia malayi	Pre-SET motif family protein	0.0212	0.2212	0.3899
Brugia malayi	Bromodomain containing protein	0.0029	0.0146	0.0247
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Echinococcus multilocularis	SAM and MBT domain containing protein	0.0399	0.4331	0.5957
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.002	0.0052	0.0063
Brugia malayi	Cytochrome P450 family protein	0.0023	0.0087	0.0142
Toxoplasma gondii	ABC1 family protein	0.0035	0.022	0.1118
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0018	0.0024	0.0018
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0057	0.0462	0.5
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0023	0.0083	0.0135
Schistosoma mansoni	hypothetical protein	0.0022	0.0076	0.007
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0047	0.0353	0.0612
Brugia malayi	intermediate filament protein	0.0027	0.0125	0.021
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0045	0.0327	0.0576
Brugia malayi	hypothetical protein	0.005	0.0387	0.0673
Schistosoma mansoni	lar interacting protein (lip)-related protein	0.0026	0.0118	0.0112
Schistosoma mansoni	scm-relatedprotein containing 4 mbt domains (sfmbt)	0.0399	0.4331	0.4328
Entamoeba histolytica	hypothetical protein	0.005	0.0388	0.3516
Toxoplasma gondii	exonuclease III APE	0.0057	0.0462	0.2383
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.022	0.0388
Entamoeba histolytica	hypothetical protein	0.0106	0.1019	1
Trypanosoma brucei	DNA polymerase eta, putative	0.002	0.0052	0.0145
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0051	0.0397	0.1233
Schistosoma mansoni	aldehyde dehydrogenase	0.0186	0.1919	0.1914
Plasmodium falciparum	GTP-binding nuclear protein RAN/TC4	0.0023	0.0083	0.118
Onchocerca volvulus		0.0026	0.0118	0.0166
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0018	0.0024	0.0025
Echinococcus multilocularis	uro adherence factor A	0.0018	0.0024	0.0025
Brugia malayi	PHD-finger family protein	0.0018	0.0024	0.0032
Echinococcus granulosus	lamin	0.0027	0.0125	0.0163
Echinococcus granulosus	PHD finger protein rhinoceros	0.0029	0.0146	0.0192
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0237	0.0726
Loa Loa (eye worm)	CYP4Cod1	0.0023	0.0087	0.0111
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0019	0.0037	0.0065
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Loa Loa (eye worm)	hypothetical protein	0.0027	0.013	0.0171
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0018	0.0024	0.0025
Schistosoma mansoni	hypothetical protein	0.0659	0.7266	0.7265
Echinococcus granulosus	polyhomeotic protein 2	0.0026	0.0118	0.0154
Mycobacterium tuberculosis	Probable esterase LipL	0.0035	0.022	0.0299
Entamoeba histolytica	Ran family GTPase	0.0023	0.0083	0.038
Schistosoma mansoni	Protein aveugle	0.0026	0.0118	0.0112
Trichomonas vaginalis	ran, putative	0.0023	0.0083	0.0146
Plasmodium falciparum	ataxin-2 like protein, putative	0.005	0.0387	0.7325
Brugia malayi	mbt repeat family protein	0.0287	0.3062	0.54
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0047	0.0353	0.0477
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0035	0.022	0.0294
Echinococcus granulosus	sterile alpha and tir motif containing protein	0.0026	0.0118	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0062	0.052	0.0707
Onchocerca volvulus		0.0031	0.0175	0.0267
Schistosoma mansoni	bromodomain containing protein	0.0018	0.0024	0.0018
Echinococcus multilocularis	phd finger protein 10	0.0018	0.0024	0.0025
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0042	0.0294	0.0908
Echinococcus granulosus	phd finger protein 10	0.0018	0.0024	0.0025
Schistosoma mansoni	ran	0.0023	0.0083	0.0077
Plasmodium vivax	protein kinase, putative	0.0026	0.0118	0.1887
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0237	0.0418
Schistosoma mansoni	hypothetical protein	0.0018	0.0024	0.0018
Toxoplasma gondii	PHD-finger domain-containing protein	0.0018	0.0024	0.0095
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Schistosoma mansoni	jumonji domain containing protein	0.0101	0.0962	0.0956
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0035	0.022	0.0299
Schistosoma mansoni	hypothetical protein	0.0029	0.0146	0.014
Loa Loa (eye worm)	hypothetical protein	0.0035	0.022	0.0294
Schistosoma mansoni	tar DNA-binding protein	0.0065	0.056	0.0554
Schistosoma mansoni	terminal deoxycytidyl transferase	0.002	0.0052	0.0046
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0045	0.0327	0.0321
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.002	0.0052	0.0145
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Loa Loa (eye worm)	hypothetical protein	0.0035	0.022	0.0294
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0042	0.0292	0.1497
Trypanosoma cruzi	Ring finger domain/PHD-finger, putative	0.0018	0.0024	0.0057
Toxoplasma gondii	PHD-finger domain-containing protein	0.0018	0.0024	0.0095
Mycobacterium ulcerans	hypothetical protein	0.0518	0.5665	1
Mycobacterium tuberculosis	Conserved protein	0.0035	0.022	0.0299
Trichomonas vaginalis	ap endonuclease, putative	0.0057	0.0462	0.0815
Brugia malayi	hypothetical protein	0.0026	0.0118	0.0197
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0018	0.0024	0.0025
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0186	0.1919	0.3325
Echinococcus multilocularis	tumor suppressor p53 binding protein 1	0.034	0.3657	0.5028
Brugia malayi	C2-HC type zinc finger protein C.e-MyT1	0.0099	0.0945	0.1659
Echinococcus granulosus	lysine specific demethylase 5B	0.0018	0.0024	0.0025
Brugia malayi	PHD-finger family protein	0.0018	0.0024	0.0032
Schistosoma mansoni	hypothetical protein	0.0018	0.0024	0.0018
Brugia malayi	PHD-finger family protein	0.0018	0.0024	0.0032
Onchocerca volvulus		0.0241	0.2542	0.4462
Loa Loa (eye worm)	jmjC domain-containing protein	0.0179	0.1839	0.2524
Giardia lamblia	Transglutaminase/protease, putative	0.0518	0.5665	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Trypanosoma cruzi	hypothetical protein, conserved	0.0035	0.022	0.0674
Brugia malayi	PHD-finger family protein	0.0018	0.0024	0.0032
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0212	0.2212	0.3039
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0456	0.062
Schistosoma mansoni	cpg binding protein	0.0031	0.0175	0.0169
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0023	0.0083	0.0241
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0327	0.0441
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0045	0.0327	0.0321
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Echinococcus granulosus	histone acetyltransferase myst3	0.0044	0.032	0.0432
Brugia malayi	Pre-SET motif family protein	0.0031	0.0172	0.0293
Leishmania major	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Schistosoma mansoni	hypothetical protein	0.0047	0.0353	0.0347
Loa Loa (eye worm)	hypothetical protein	0.0035	0.022	0.0294
Brugia malayi	RNA, U transporter 1	0.0176	0.1805	0.3179
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0172	0.0166
Toxoplasma gondii	histone lysine demethylase JMJC1/KDM5D/JARID1D	0.0043	0.0306	0.1567
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0065	0.056	0.0763
Toxoplasma gondii	inositol(myo)-1(or 4)-monophosphatase 2, putative	0.0037	0.0237	0.1204
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0022	0.0076	0.0096
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0047	0.0353	0.0477
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0186	0.1919	0.3325
Trypanosoma cruzi	DNA polymerase eta, putative	0.002	0.0052	0.0145
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0023	0.0083	0.0105
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Mycobacterium ulcerans	transglutaminase family protein	0.0518	0.5665	1
Brugia malayi	Latrophilin receptor protein 2	0.0047	0.0353	0.0612
Schistosoma mansoni	hypothetical protein	0.0047	0.0353	0.0347
Onchocerca volvulus		0.0026	0.0118	0.0166
Brugia malayi	F/Y-rich N-terminus family protein	0.0036	0.023	0.0396
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.0172	0.0166
Echinococcus multilocularis	neuropeptide s receptor	0.0454	0.4951	0.681
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0186	0.1919	0.6031
Mycobacterium tuberculosis	Hypothetical protein	0.0518	0.5665	1
Mycobacterium leprae	Conserved hypothetical protein	0.0518	0.5665	1
Echinococcus multilocularis	GPCR, family 2	0.0047	0.0353	0.0477
Echinococcus granulosus	histone acetyltransferase myst4	0.0018	0.0024	0.0025
Schistosoma mansoni	lamin	0.0027	0.0125	0.0119
Schistosoma mansoni	hypothetical protein	0.0047	0.0353	0.0347
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Mycobacterium tuberculosis	Probable hydrolase	0.0035	0.022	0.0299
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0023	0.0083	0.0105
Echinococcus multilocularis	lysine specific demethylase 5B	0.0018	0.0024	0.0025
Echinococcus granulosus	lysine specific demethylase 5A	0.0133	0.1324	0.1815
Brugia malayi	latrophilin 2 splice variant baaae	0.0101	0.0968	0.17
Brugia malayi	Hypothetical C28H8.9 in chromosome III	0.0018	0.0024	0.0032
Brugia malayi	Cytochrome P450 family protein	0.0023	0.0087	0.0142
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Brugia malayi	PHD-finger family protein	0.0027	0.013	0.0219
Echinococcus granulosus	histone lysine methyltransferase setb	0.0031	0.0172	0.0228
Onchocerca volvulus		0.0026	0.0118	0.0166
Schistosoma mansoni	phd finger protein	0.0018	0.0024	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0035	0.022	0.0294
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0133	0.1324	0.1319
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0052	0.0145
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0023	0.0083	0.0241
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0031	0.0172	0.0228
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0052	0.0145
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.0146	0.073
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0172	0.0228
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0019	0.0037	0.0065
Schistosoma mansoni	myst-related protein	0.002	0.0046	0.004
Toxoplasma gondii	GTP-binding nuclear protein ran/tc4	0.0023	0.0083	0.04
Echinococcus granulosus	tumor suppressor p53 binding protein 1	0.034	0.3657	0.5028
Trypanosoma cruzi	cytochrome P450, putative	0.0023	0.0087	0.0253
Schistosoma mansoni	hypothetical protein	0.0018	0.0024	0.0018
Trypanosoma brucei	hypothetical protein, conserved	0.0035	0.022	0.0674
Trypanosoma brucei	Ring finger domain/PHD-finger, putative	0.0018	0.0024	0.0057
Loa Loa (eye worm)	PHD-finger family protein	0.0029	0.0146	0.0192
Echinococcus multilocularis	neuropeptide receptor A26	0.0454	0.4951	0.681
Schistosoma mansoni	importin beta-1	0.0062	0.052	0.0514
Echinococcus granulosus	endonuclease exonuclease phosphatase	0.0552	0.6059	0.8337
Loa Loa (eye worm)	cytochrome P450 family protein	0.0023	0.0087	0.0111
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0148	0.1498	0.2637
Mycobacterium leprae	Conserved hypothetical protein	0.0518	0.5665	1
Brugia malayi	Thioredoxin family protein	0.0518	0.5665	1
Schistosoma mansoni	myst histone acetyltransferase	0.0018	0.0024	0.0018
Echinococcus multilocularis	peregrin	0.0029	0.0146	0.0192
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0029	0.0146	0.014
Echinococcus granulosus	PHD and RING finger domain containing protein 1	0.0018	0.0024	0.0025
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.002	0.0052	0.0046
Trichomonas vaginalis	inhibitor of growth, putative	0.0018	0.0024	0.0043
Brugia malayi	jmjC domain containing protein	0.0179	0.1839	0.3239
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.002	0.0052	0.0092
Mycobacterium tuberculosis	Probable lipase LipE	0.0035	0.022	0.0299
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0035	0.022	0.0299
Echinococcus multilocularis	PHD finger protein 14	0.0018	0.0024	0.0025
Brugia malayi	hypothetical protein	0.0018	0.0024	0.0032
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0057	0.0462	0.073
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0093	0.0872	0.1193
Echinococcus granulosus	Transglutaminase	0.0518	0.5665	0.7795
Echinococcus multilocularis	pdz domain containing protein	0.0026	0.0118	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Trypanosoma cruzi	PAB1-binding protein , putative	0.005	0.0387	0.1201
Trypanosoma brucei	cytochrome P450, putative	0.0023	0.0087	0.0253
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0106	0.1019	0.1394
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0057	0.0462	0.1437
Trypanosoma brucei	inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0237	0.0726
Brugia malayi	AIDA-1b	0.0026	0.0118	0.0197
Plasmodium vivax	GTP-binding nuclear protein RAN/TC4, putative	0.0023	0.0083	0.118
Giardia lamblia	Hypothetical protein	0.0518	0.5665	1
Brugia malayi	RNA binding protein	0.0065	0.056	0.0979
Schistosoma mansoni	DNAj-like protein	0.0026	0.0118	0.0112
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.022	0.0214
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0019	0.0037	0.0065
Echinococcus granulosus	TAF3 RNA polymerase II TATA box binding protein	0.0018	0.0024	0.0025
Echinococcus multilocularis	musashi	0.0027	0.0125	0.0163
Loa Loa (eye worm)	hypothetical protein	0.0099	0.0945	0.1293
Echinococcus granulosus	phd finger protein 12	0.0018	0.0024	0.0025
Schistosoma mansoni	cpg binding protein	0.0049	0.0377	0.0371
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0047	0.0353	0.0477
Loa Loa (eye worm)	jmjC domain-containing protein	0.0059	0.049	0.0667
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Mycobacterium tuberculosis	Conserved protein	0.0518	0.5665	1
Echinococcus multilocularis	sterile alpha and tir motif containing protein	0.0026	0.0118	0.0154
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0018	0.0024	0.0025
Loa Loa (eye worm)	hypothetical protein	0.005	0.0387	0.0525
Echinococcus multilocularis	inositol monophosphatase 1	0.0037	0.0237	0.0317
Toxoplasma gondii	hypothetical protein	0.0048	0.0364	0.1868
Echinococcus granulosus	neuropeptide s receptor	0.0454	0.4951	0.681
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0297	0.3177	1
Toxoplasma gondii	AP2 domain transcription factor AP2VIIa-7	0.0018	0.0024	0.0095
Echinococcus granulosus	jumonji domain containing protein	0.004	0.0273	0.0367
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0148	0.1498	0.2637
Trypanosoma cruzi	Kinesin-13 5, putative	0.0026	0.0118	0.0352
Onchocerca volvulus		0.002	0.0045	0.0036
Trichomonas vaginalis	c2h2 zinc finger protein, putative	0.0026	0.0118	0.0208
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0022	0.0076	0.0096
Brugia malayi	ImpB/MucB/SamB family protein	0.002	0.0052	0.0081
Onchocerca volvulus	Alhambra homolog	0.0029	0.0146	0.0215
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.002	0.0052	0.0063
Echinococcus multilocularis	polycomb protein SCMH1	0.0276	0.2936	0.4035
Echinococcus multilocularis	chromodomain helicase DNA binding protein 4	0.003	0.0159	0.0211
Schistosoma mansoni	chromobox protein	0.0205	0.2131	0.2127
Echinococcus multilocularis	lamin dm0	0.0027	0.0125	0.0163
Brugia malayi	PHD-finger family protein	0.0029	0.0146	0.0247
Schistosoma mansoni	hypothetical protein	0.0177	0.1825	0.1819
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0057	0.0462	0.073
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Mycobacterium ulcerans	hypothetical protein	0.0035	0.022	0.0299
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0518	0.5665	1
Echinococcus multilocularis	Transglutaminase	0.0518	0.5665	0.7795
Plasmodium falciparum	zinc finger protein, putative	0.002	0.0046	0.0434
Brugia malayi	SET domain containing protein	0.002	0.0045	0.0068
Echinococcus multilocularis	histone acetyltransferase myst4	0.0018	0.0024	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Loa Loa (eye worm)	PHD-finger family protein	0.0018	0.0024	0.0025
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0518	0.5665	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Brugia malayi	exodeoxyribonuclease III family protein	0.0057	0.0462	0.0805
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Entamoeba histolytica	hypothetical protein	0.0106	0.1019	1
Mycobacterium ulcerans	extragenic suppressor protein SuhB	0.0037	0.0237	0.0328
Schistosoma mansoni	hypothetical protein	0.034	0.3657	0.3653
Trichomonas vaginalis	cgi-62, putative	0.0026	0.0118	0.0208
Toxoplasma gondii	HEAT repeat-containing protein	0.0062	0.052	0.2685
Leishmania major	DNA polymerase eta, putative	0.002	0.0052	0.0145
Brugia malayi	beta-lactamase	0.0035	0.022	0.0378
Schistosoma mansoni	requim req/dpf2	0.0018	0.0024	0.0018
Brugia malayi	TAR-binding protein	0.0065	0.056	0.0979
Echinococcus granulosus	beta LACTamase domain containing family member	0.0035	0.022	0.0294
Leishmania major	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0237	0.0726
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0023	0.0087	0.0061
Entamoeba histolytica	hypothetical protein	0.0106	0.1019	1
Trichomonas vaginalis	DNA polymerase eta, putative	0.002	0.0052	0.0092
Echinococcus granulosus	chromobox protein 2	0.0205	0.2131	0.2927
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0.0327	0.0576
Echinococcus granulosus	Sterile alpha motif SAM	0.0026	0.0118	0.0154
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0186	0.1919	0.3325
Mycobacterium ulcerans	hypothetical protein	0.0518	0.5665	1
Leishmania major	hypothetical protein, conserved	0.005	0.0387	0.1201
Echinococcus granulosus	liprin alpha 2	0.0026	0.0118	0.0154
Echinococcus granulosus	Sterile alpha motif type	0.0026	0.0118	0.0154
Leishmania major	mitochondrial DNA polymerase beta	0.0297	0.3177	1
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0067	0.0582	0.0577
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Mycobacterium tuberculosis	Probable lipase LipD	0.0035	0.022	0.0299
Echinococcus granulosus	dna polymerase kappa	0.002	0.0052	0.0063
Echinococcus granulosus	polyhomeotic proximal chromatin protein	0.0026	0.0118	0.0154
Echinococcus multilocularis	lamin	0.0027	0.0125	0.0163
Echinococcus granulosus	dna polymerase eta	0.002	0.0052	0.0063
Schistosoma mansoni	zinc finger protein	0.0018	0.0024	0.0018
Schistosoma mansoni	hypothetical protein	0.0018	0.0024	0.0018
Echinococcus granulosus	zinc finger protein	0.0018	0.0024	0.0025
Trypanosoma cruzi	hypothetical protein, conserved	0.0035	0.022	0.0674
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Schistosoma mansoni	SET domain protein	0.002	0.0045	0.0038
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0018	0.0024	0.0025
Plasmodium vivax	SET domain protein, putative	0.0031	0.0172	0.2977
Echinococcus granulosus	liprin alpha 2	0.0026	0.0118	0.0154
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0019	0.0037	0.0065
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0045	0.0327	0.0489
Trichomonas vaginalis	inositol monophosphatase, putative	0.0037	0.0237	0.0418
Mycobacterium ulcerans	hypothetical protein	0.0157	0.159	0.2739
Echinococcus multilocularis	Zinc finger, DBF type	0.0018	0.0024	0.0025
Echinococcus granulosus	cpg binding protein	0.0049	0.0377	0.051
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0057	0.0462	1
Trypanosoma cruzi	Kinesin-13 5, putative	0.0026	0.0118	0.0352
Leishmania major	mitochondrial DNA polymerase beta-PAK, putative	0.0141	0.141	0.4427
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0093	0.0872	0.1193
Brugia malayi	jmjC domain containing protein	0.012	0.118	0.2073
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0133	0.1324	0.1319
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	0.0129	0.1284	0.176
Trypanosoma brucei	DNA polymerase beta thumb, putative	0.0042	0.0294	0.0908
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0035	0.022	0.0294
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0042	0.0294	0.0908
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0023	0.0083	0.0241
Schistosoma mansoni	tar DNA-binding protein	0.0065	0.056	0.0554
Schistosoma mansoni	hypothetical protein	0.0026	0.0118	0.0112
Loa Loa (eye worm)	TAR-binding protein	0.0065	0.056	0.0763
Loa Loa (eye worm)	AIDA-1b	0.0026	0.0118	0.0154
Schistosoma mansoni	DNA polymerase eta	0.002	0.0052	0.0046
Onchocerca volvulus		0.0035	0.022	0.0347
Mycobacterium tuberculosis	Conserved protein	0.0035	0.022	0.0299
Brugia malayi	hypothetical protein	0.0018	0.0024	0.0032
Echinococcus granulosus	tar DNA binding protein	0.0065	0.056	0.0763
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0093	0.0872	0.1193
Echinococcus granulosus	pdz domain containing protein	0.0026	0.0118	0.0154
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0031	0.0175	0.0232
Toxoplasma gondii	PHD-finger domain-containing protein	0.0018	0.0024	0.0095
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.022	0.0214
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0057	0.0462	0.0628
Echinococcus multilocularis	dna polymerase eta	0.002	0.0052	0.0063
Schistosoma mansoni	zinc finger protein	0.0018	0.0024	0.0018
Giardia lamblia	Kinesin-13	0.0026	0.0118	0.0117
Entamoeba histolytica	hypothetical protein	0.0106	0.1019	1
Trypanosoma brucei	mitochondrial DNA polymerase beta	0.0297	0.3177	1
Entamoeba histolytica	myo-inositol monophosphatase, putative	0.0037	0.0237	0.1961
Leishmania major	GTP-binding protein, putative	0.0023	0.0083	0.0241
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0237	0.0726
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0237	0.023
Trichomonas vaginalis	penicillin-binding protein, putative	0.0035	0.022	0.0388
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Loa Loa (eye worm)	RNA binding protein	0.0065	0.056	0.0763
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0057	0.0462	0.8834
Echinococcus multilocularis	cpg binding protein	0.0049	0.0377	0.051
Echinococcus granulosus	Zinc finger DBF type	0.0018	0.0024	0.0025
Brugia malayi	Bromodomain containing protein	0.0018	0.0024	0.0032
Schistosoma mansoni	hepatitis B virus X associated protein hbxa	0.0018	0.0024	0.0018
Brugia malayi	hypothetical protein	0.0026	0.0118	0.0197
Toxoplasma gondii	aldehyde dehydrogenase	0.0186	0.1919	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Schistosoma mansoni	tar DNA-binding protein	0.0065	0.056	0.0554
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0297	0.3177	1
Schistosoma mansoni	fyve-containing	0.0018	0.0024	0.0018
Echinococcus multilocularis	liprin alpha 2	0.0026	0.0118	0.0154
Plasmodium falciparum	importin beta, putative	0.0062	0.052	1
Trypanosoma cruzi	Ring finger domain/PHD-finger, putative	0.0018	0.0024	0.0057
Schistosoma mansoni	intermediate filament proteins	0.0027	0.0125	0.0119
Echinococcus granulosus	lamin dm0	0.0027	0.0125	0.0163
Trypanosoma brucei	importin beta-1 subunit, putative	0.0062	0.052	0.1619
Leishmania major	cytochrome p450-like protein	0.0023	0.0087	0.0253
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0045	0.0327	0.101
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0659	0.7266	1
Toxoplasma gondii	hypothetical protein	0.0027	0.0122	0.0606
Schistosoma mansoni	sex comb on midleg homolog	0.0276	0.2936	0.2931
Echinococcus multilocularis	ubiquitin specific protease 41	0.0045	0.0327	0.0441
Brugia malayi	hypothetical protein	0.0106	0.1019	0.1789
Echinococcus multilocularis	snurportin 1	0.0659	0.7266	1
Schistosoma mansoni	ap endonuclease	0.0057	0.0462	0.0456
Mycobacterium ulcerans	lipase LipD	0.0035	0.022	0.0299
Schistosoma mansoni	aldehyde dehydrogenase	0.0186	0.1919	0.1914
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0177	0.1825	0.3192
Plasmodium vivax	hypothetical protein, conserved	0.0035	0.022	0.395
Trypanosoma cruzi	cytochrome P450, putative	0.0023	0.0087	0.0253
Echinococcus granulosus	inositol monophosphatase 1	0.0037	0.0237	0.0317
Schistosoma mansoni	hypothetical protein	0.0445	0.4841	0.4838
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.012	0.118	0.1616
Loa Loa (eye worm)	hypothetical protein	0.0177	0.1825	0.2505
Echinococcus multilocularis	PHD and RING finger domain containing protein 1	0.0018	0.0024	0.0025
Trypanosoma brucei	SAM domain (Sterile alpha motif), putative	0.0026	0.0118	0.0352
Brugia malayi	bicaudal-C	0.0026	0.0118	0.0197
Echinococcus granulosus	fetal alzheimer antigen falz	0.0018	0.0024	0.0025
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.022	0.0388
Giardia lamblia	GTP-binding nuclear protein RAN/TC4	0.0023	0.0083	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0019	0.0037	0.0065
Trypanosoma brucei	PAB1-binding protein , putative	0.005	0.0387	0.1201
Schistosoma mansoni	hypothetical protein	0.0518	0.5665	0.5663
Loa Loa (eye worm)	hypothetical protein	0.0035	0.022	0.0294
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0057	0.0462	0.1437
Echinococcus granulosus	suppression of tumorigenicity 18 protein	0.0099	0.0945	0.1293
Brugia malayi	Importin beta-1 subunit	0.0062	0.052	0.0907
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0093	0.0872	0.1193
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0057	0.0462	0.0628
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0043	0.0307	0.0301
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0035	0.022	0.0378
Onchocerca volvulus	Tankyrase homolog	0.0026	0.0118	0.0166
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0119	0.0156
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0093	0.0872	0.0866
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0093	0.0872	0.153
Echinococcus granulosus	chromodomain helicase DNA binding protein 4	0.003	0.0159	0.0211
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0035	0.022	0.0299
Brugia malayi	Intermediate filament tail domain containing protein	0.0027	0.0125	0.021
Echinococcus multilocularis	endonuclease exonuclease phosphatase	0.0552	0.6059	0.8337
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0045	0.0327	0.101
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Onchocerca volvulus		0.0518	0.5665	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Mycobacterium ulcerans	beta-lactamase	0.0035	0.022	0.0299
Loa Loa (eye worm)	hypothetical protein	0.0148	0.1498	0.2055
Schistosoma mansoni	tar DNA-binding protein	0.0065	0.056	0.0554
Schistosoma mansoni	zinc finger protein	0.0018	0.0024	0.0018
Echinococcus multilocularis	histone acetyltransferase myst3	0.0044	0.032	0.0432
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0045	0.0327	0.101
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.0146	0.073
Trichomonas vaginalis	ap endonuclease, putative	0.0057	0.0462	0.0815
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0186	0.1919	0.3325
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0029	0.0152	0.02
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0045	0.0327	0.0566
Schistosoma mansoni	ap endonuclease	0.0057	0.0462	0.0456
Loa Loa (eye worm)	F/Y-rich family protein	0.0018	0.0024	0.0025
Leishmania major	importin beta-1 subunit, putative	0.005	0.0388	0.1203
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0057	0.0462	0.4278
Echinococcus multilocularis	TAF3 RNA polymerase II, TATA box binding protein	0.0018	0.0024	0.0025
Echinococcus granulosus	SAM and MBT domain containing protein	0.0399	0.4331	0.5957
Plasmodium falciparum	phd finger protein, putative	0.0029	0.0146	0.2453
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0045	0.0327	0.0441
Echinococcus multilocularis	polyhomeotic protein 2	0.0026	0.0118	0.0154
Toxoplasma gondii	SWI2/SNF2-containing PHD finger protein	0.0018	0.0024	0.0095
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0146	0.0192
Mycobacterium tuberculosis	Long conserved protein	0.0518	0.5665	1
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0047	0.0353	0.0477
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0019	0.0037	0.0065
Schistosoma mansoni	tar DNA-binding protein	0.0065	0.056	0.0554
Schistosoma mansoni	bromodomain containing protein	0.0018	0.0024	0.0018
Onchocerca volvulus		0.0035	0.022	0.0347
Mycobacterium ulcerans	putative transglutaminase-like protein	0.0518	0.5665	1
Brugia malayi	CHD4 protein	0.003	0.0159	0.027
Brugia malayi	cask-interacting protein 2	0.0026	0.0118	0.0197
Onchocerca volvulus		0.0026	0.0118	0.0166
Schistosoma mansoni	lamin	0.0027	0.0125	0.0119
Onchocerca volvulus		0.0026	0.0118	0.0166
Schistosoma mansoni	transcription factor LCR-F1	0.0106	0.1019	0.1013
Trichomonas vaginalis	penicillin-binding protein, putative	0.0035	0.022	0.0388
Leishmania major	hypothetical protein, conserved	0.0035	0.022	0.0674
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	0.0129	0.1284	0.176
Trichomonas vaginalis	conserved hypothetical protein	0.0026	0.0118	0.0208
Loa Loa (eye worm)	toll and interleukin 1 receptor domain-containing protein isoform f	0.0026	0.0118	0.0154
Echinococcus multilocularis	histone acetyltransferase MYST2	0.0099	0.0945	0.1293
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0118	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0024	0.0043
Brugia malayi	ImpB/MucB/SamB family protein	0.002	0.0052	0.0081
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0057	0.0462	0.073
Trypanosoma cruzi	importin beta-1 subunit, putative	0.005	0.0388	0.1203
Echinococcus multilocularis	remodeling and spacing factor 1	0.0018	0.0024	0.0025
Schistosoma mansoni	hypothetical protein	0.0106	0.1019	0.1013
Loa Loa (eye worm)	cytochrome P450 family protein	0.0023	0.0087	0.0111
Schistosoma mansoni	hypothetical protein	0.0101	0.0968	0.0962
Echinococcus multilocularis	importin subunit beta 1	0.0062	0.052	0.0707
Echinococcus multilocularis	polyhomeotic proximal chromatin protein	0.0026	0.0118	0.0154
Schistosoma mansoni	myelin transcription factor 1 myt1	0.0099	0.0945	0.094
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0045	0.0327	0.0441
Echinococcus multilocularis	Sterile alpha motif type	0.0026	0.0118	0.0154
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0047	0.0353	0.0477
Trichomonas vaginalis	importin beta-1, putative	0.005	0.0388	0.0685
Loa Loa (eye worm)	hypothetical protein	0.0035	0.022	0.0294
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.022	0.0388
Echinococcus multilocularis	dna polymerase kappa	0.002	0.0052	0.0063
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0042	0.0294	0.0908
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0029	0.0146	0.0192
Trypanosoma brucei	Present in the outer mitochondrial membrane proteome 24	0.0026	0.0118	0.0352
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0019	0.0037	0.0065
Brugia malayi	Sphingomyelin synthase-related 1	0.0026	0.0118	0.0197
Trichomonas vaginalis	esterase, putative	0.0035	0.022	0.0388
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Schistosoma mansoni	chromodomain helicase DNA binding protein	0.003	0.0159	0.0153
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0237	0.023
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0045	0.0327	0.2886
Echinococcus granulosus	intermediate filament protein	0.0027	0.0125	0.0163
Brugia malayi	PHD-finger family protein	0.0018	0.0024	0.0032
Schistosoma mansoni	hypothetical protein	0.0047	0.0353	0.0347
Onchocerca volvulus		0.0026	0.0118	0.0166
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0057	0.0462	0.8834
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Mycobacterium leprae	conserved hypothetical protein	0.0035	0.022	0.0049
Echinococcus granulosus	neuropeptide receptor A26	0.0454	0.4951	0.681
Trichomonas vaginalis	set domain proteins, putative	0.0241	0.2542	0.4486
Schistosoma mansoni	hypothetical protein	0.0177	0.1825	0.1819
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0045	0.0327	0.0441
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0024	0.0025
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0148	0.1498	0.2055
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0141	0.141	0.4427
Schistosoma mansoni	hypothetical protein	0.0026	0.0118	0.0112
Echinococcus granulosus	snurportin 1	0.0659	0.7266	1
Brugia malayi	N-terminal motif family protein	0.0177	0.1825	0.3214
Loa Loa (eye worm)	cytochrome P450 family protein	0.0036	0.0227	0.0304
Onchocerca volvulus		0.0027	0.0125	0.0178
Plasmodium vivax	importin-beta 2, putative	0.0062	0.052	1
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0106	0.1019	0.1394
Loa Loa (eye worm)	hypothetical protein	0.0101	0.0968	0.1325
Brugia malayi	hypothetical protein	0.0032	0.0187	0.032
Trypanosoma brucei	mitochondrial DNA polymerase beta-PAK	0.0141	0.141	0.4427
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0237	0.0418
Schistosoma mansoni	hypothetical protein	0.0018	0.0024	0.0018
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0186	0.1919	0.2634
Echinococcus multilocularis	liprin alpha 2	0.0026	0.0118	0.0154
Echinococcus granulosus	remodeling and spacing factor 1	0.0018	0.0024	0.0025
Loa Loa (eye worm)	intermediate filament protein	0.0027	0.0125	0.0163
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0186	0.1919	0.2634
Echinococcus granulosus	polycomb protein SCMH1	0.0276	0.2936	0.4035
Echinococcus multilocularis	chromobox protein 2	0.0205	0.2131	0.2927
Brugia malayi	CXXC zinc finger family protein	0.0031	0.0175	0.0298
Loa Loa (eye worm)	mbt repeat family protein	0.0287	0.3062	0.4209
Brugia malayi	RNA recognition motif domain containing protein	0.0065	0.056	0.0979
Echinococcus granulosus	ubiquitin specific protease 41	0.0045	0.0327	0.0441
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0019	0.0037	0.0065
Plasmodium vivax	ataxin-2 like protein, putative	0.005	0.0387	0.7325
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0035	0.022	0.0299
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0052	0.0145
Echinococcus multilocularis	sphingomyelin synthase protein 1	0.0026	0.0118	0.0154
Brugia malayi	mbt repeat family protein	0.0474	0.5179	0.914
Loa Loa (eye worm)	CHromoDomain protein family member	0.003	0.0159	0.0211
Brugia malayi	Cytochrome P450 family protein	0.0036	0.0227	0.0391
Brugia malayi	Inositol-1	0.0037	0.0237	0.0407
Echinococcus granulosus	histone acetyltransferase MYST2	0.0099	0.0945	0.1293
Schistosoma mansoni	spingomyelin synthetase-related	0.0026	0.0118	0.0112
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0023	0.0083	0.0105
Echinococcus granulosus	uro adherence factor A	0.0018	0.0024	0.0025
Schistosoma mansoni	myst-related protein	0.002	0.0046	0.004
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0018	0.0028	0.0022
Brugia malayi	Liprin-alpha 2	0.0026	0.0118	0.0197
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0045	0.0327	0.101
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.005	0.0388	0.0685
Mycobacterium tuberculosis	Conserved protein	0.0035	0.022	0.0299
Schistosoma mansoni	dpf3	0.0018	0.0024	0.0018
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.012	0.118	0.1616
Onchocerca volvulus	Polycomb protein Sfmbt homolog	0.0474	0.5179	0.9138
Schistosoma mansoni	ran	0.0023	0.0083	0.0077
Brugia malayi	beta-lactamase family protein	0.0035	0.022	0.0378
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0045	0.0327	0.0441
Echinococcus granulosus	GPCR family 2	0.0047	0.0353	0.0477
Giardia lamblia	Giardia trophozoite antigen GTA-1	0.0026	0.0118	0.0117

Activities

Activity type	Activity value	Assay description	Source	Reference
AC50 (functional)	= 1.258925412 uM	PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active	ChEMBL.	No reference
AC50 (functional)	= 7.943282347 uM	PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active	ChEMBL.	No reference
AC50 (functional)	= 15.84893192 uM	PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active	ChEMBL.	No reference
AC50 (functional)	= 25.11886432 uM	PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active	ChEMBL.	No reference
AC50 (functional)	= 39.81071706 uM	PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active	ChEMBL.	No reference
Potency (ADMET)	= 1.2589 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ]	ChEMBL.	No reference
Potency (functional)	= 12.5893 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (ADMET)	= 15.8489 um	PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ]	ChEMBL.	No reference
Potency (ADMET)	= 15.8489 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ]	ChEMBL.	No reference
Potency (functional)	= 19.9526 um	PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 19.9526 um	PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (ADMET)	= 25.1189 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9. (Class of assay: confirmatory) [Related pubchem assays: 885, 884, 410 ]	ChEMBL.	No reference
Potency (functional)	= 39.8107 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))]	ChEMBL.	No reference
Potency (ADMET)	= 39.8107 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ]	ChEMBL.	No reference
Potency (functional)	50.1187 uM	PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1553941

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1427908