Detailed information for compound 1543023

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 309.766 | Formula: C11H16ClNO5S
  • H donors: 1 H acceptors: 2 LogP: 1.43 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClCS(=O)(=O)NCc1cc(OC)c(c(c1)OC)OC
  • InChi: 1S/C11H16ClNO5S/c1-16-9-4-8(6-13-19(14,15)7-12)5-10(17-2)11(9)18-3/h4-5,13H,6-7H2,1-3H3
  • InChiKey: ZGGCBKITFDAQGV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major P-type H -ATPase, putative 0.0009 0.0082 0.096
Trypanosoma cruzi proton motive ATPase 1, putative 0.0009 0.0082 0.096
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0605 0.0903
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0029 0.0036
Schistosoma mansoni glucose transport protein 0.0101 0.226 0.5052
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0009 0.0082 0.011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0141 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni apoferritin-2 0.0009 0.0082 0.0184
Schistosoma mansoni apoferritin-2 0.0009 0.0082 0.0184
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0071 0.0159
Schistosoma mansoni ferritin 0.0009 0.0082 0.0184
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0009 0.0082 0.0128
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0516 0.0855
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0082 0.0182
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0082 0.0128
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0709 0.9236
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0006 0.0015 0.0034
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0605 0.1352
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0322 0.0534
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0009 0.0082 0.0135
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0614 0.799
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0113 0.0252
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0009 0.0082 0.0182
Onchocerca volvulus 0.0027 0.0516 0.0906
Schistosoma mansoni inositol monophosphatase 0.0038 0.0767 0.1714
Echinococcus granulosus copper transporting ATPase 1 0.0009 0.0082 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0192 0.4392 0.9817
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0082 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0605 0.1048
Giardia lamblia Sugar-proton symporter 0.0014 0.021 0.2173
Schistosoma mansoni bromodomain containing protein 0.0006 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0605 0.1002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.1078 0.241
Onchocerca volvulus 0.0014 0.021 0.0369
Loa Loa (eye worm) E1-E2 ATPase 0.0009 0.0082 0.0135
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0009 0.0082 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0614 0.1065
Onchocerca volvulus Putative transporter 0.0014 0.021 0.0369
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.021 0.0348
Onchocerca volvulus 0.0014 0.021 0.0369
Brugia malayi Na,K-ATPase alpha subunit 0.0009 0.0082 0.0135
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0605 0.0597
Schistosoma mansoni intermediate filament proteins 0.0027 0.0516 0.1154
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0141 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.226 0.5052
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0009 0.0082 0.0135
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0767 1
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0009 0.0082 0.0128
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0605 0.0597
Loa Loa (eye worm) calcium ATPase 0.0009 0.0082 0.0135
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0767 0.1332
Leishmania major glucose transporter, lmgt2 0.0031 0.0614 0.799
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) hypothetical protein 0.003 0.059 0.0978
Loa Loa (eye worm) hypothetical protein 0.007 0.152 0.2518
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0141 0.0233
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0082 0.0182
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0071 0.0159
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.059 0.1022
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.021 0.0348
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0559 0.055
Toxoplasma gondii cation-transporting atpase family protein 0.0009 0.0082 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0113 0.0252
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0622 0.1389
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.011 0.0183
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0009 0.0082 0.0786
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0181 0.0405
Brugia malayi hypothetical protein 0.0006 0.0015 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.1078 0.241
Treponema pallidum cation-transporting ATPase, P-type 0.0009 0.0082 0.2322
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0009 0.0082 0.0786
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0767 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0184 0.0412
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0184 0.0412
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0141 0.0314
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0218 0.0362
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0082 0.0128
Echinococcus granulosus phospholipid transporting ATPase VA 0.0009 0.0082 0.0182
Loa Loa (eye worm) hypothetical protein 0.0006 0.001 0.0016
Brugia malayi hypothetical protein 0.0014 0.021 0.0348
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0605 0.0597
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0029 0.0036
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0605 0.1352
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni inositol monophosphatase 0.0038 0.0767 0.1714
Brugia malayi Sugar transporter family protein 0.0014 0.021 0.0348
Schistosoma mansoni ATPase 0.0009 0.0082 0.0182
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0322 0.4135
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0009 0.0082 0.096
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.152 0.2518
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0006 0.001 0.0022
Echinococcus multilocularis lamin 0.0027 0.0516 0.1154
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0009 0.0082 0.1095
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0709 0.0701
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.1031 0.2305
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.021 0.3028
Schistosoma mansoni cpg binding protein 0.0029 0.0558 0.1248
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0009 0.0082 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0614 0.1065
Brugia malayi hypothetical protein 0.0006 0.0015 0.0025
Entamoeba histolytica protein kinase, putative 0.0031 0.0605 0.6438
Schistosoma mansoni protein kinase 0.0031 0.0605 0.1352
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0141 0.0314
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0279 0.3565
Trypanosoma cruzi hexose transporter 0.0031 0.0614 0.799
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.1031 0.1797
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0516 0.0855
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0673 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0322 0.4135
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0407 0.0399
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.0025
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0141 0.0314
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0009 0.0082 0.0135
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0141 0.0314
Echinococcus granulosus General substrate transporter 0.0087 0.1925 0.4303
Brugia malayi Sugar transporter family protein 0.0014 0.021 0.0348
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0009 0.0082 0.096
Onchocerca volvulus 0.0027 0.0516 0.0906
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0605 0.7867
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.1078 0.241
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0141 0.0314
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0015 0.0025
Echinococcus multilocularis solute carrier family 22 0.0014 0.021 0.0469
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0009 0.0082 0.0972
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0559 0.7255
Brugia malayi intermediate filament protein 0.0027 0.0516 0.0855
Onchocerca volvulus 0.0011 0.0141 0.0247
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.0082 0.1109
Schistosoma mansoni ap endonuclease 0.0019 0.0322 0.072
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Schistosoma mansoni cation-transporting atpase worm 0.0009 0.0082 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Echinococcus granulosus cation transporting atpase worm 0.0009 0.0082 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni cpg binding protein 0.0031 0.0597 0.1335
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.1078 0.241
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0009 0.0082 0.0786
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.021 0.0354
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0082 0.0128
Loa Loa (eye worm) hypothetical protein 0.0023 0.0407 0.0674
Echinococcus granulosus histone acetyltransferase KAT2B 0.0163 0.3698 0.8266
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0009 0.0082 0.096
Brugia malayi nuclear receptor RXR 0.0006 0.0015 0.0025
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0006 0.0015 0.0034
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0786
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0322 1
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.021 0.0305
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0006 0.0009 0.0014
Onchocerca volvulus 0.0014 0.021 0.0369
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.021 0.0469
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0622 0.1389
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Schistosoma mansoni sugar transporter 0.0014 0.021 0.0469
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni copper ABC transporter ATPase 0.0009 0.0082 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) sugar transporter 0.0101 0.226 0.3744
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0407 0.5254
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0029 0.0036
Leishmania major protein kinase, putative 0.0031 0.0605 0.7867
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0559 0.055
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0622 0.1389
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0559 0.055
Onchocerca volvulus 0.0014 0.021 0.0369
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0407 0.5254
Brugia malayi major facilitator superfamily protein 0.0014 0.021 0.0348
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0141 0.0233
Leishmania major proton motive ATPase, putative 0.0009 0.0082 0.096
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0407 0.43
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.0168 0.0279
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.1078 0.241
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0009 0.0082 0.096
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.1351 0.3021
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0141 0.0314
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0009 0.0082 0.1095
Trichomonas vaginalis set domain proteins, putative 0.0248 0.5698 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0141 0.0314
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0128
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0009 0.0082 0.0786
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.1031 0.1548
Toxoplasma gondii protein kinase, putative 0.0287 0.6615 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0558 0.0924
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0009 0.0082 0.0135
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.021 0.2655
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0141 0.0233
Plasmodium vivax P-type ATPase4, putative 0.0009 0.0082 0.0073
Schistosoma mansoni atpase class VI type 11c 0.0009 0.0082 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0322 0.072
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.021 0.0354
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0141 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Echinococcus multilocularis solute carrier family 22 0.0014 0.021 0.0469
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0407 0.091
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0327 0.4786
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0935 0.0927
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.021 0.0469
Brugia malayi Bromodomain containing protein 0.0006 0.001 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.226 0.3957
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0767 0.1332
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.059 0.1319
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0622 0.1389
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0071 0.0159
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0709 0.9236
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0167 0.3808 0.8513
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0709 0.0701
Echinococcus granulosus intermediate filament protein 0.0027 0.0516 0.1154
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0009 0.0082 0.0182
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0128
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0009 0.0082 0.1109
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0141 0.0233
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0407 0.5254
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0767 0.1714
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0767 0.1147
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0009 0.0082 0.0182
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0709 0.9236
Trypanosoma cruzi hexose transporter, putative 0.0014 0.021 0.2655
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0015 0.0025
Brugia malayi hypothetical protein 0.0019 0.0316 0.0524
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0128
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0015 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0141 0.0233
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.1031 0.1024
Schistosoma mansoni cpg binding protein 0.0031 0.0597 0.1335
Echinococcus granulosus cation transporting ATPase 13A1 0.0009 0.0082 0.0182
Schistosoma mansoni zinc finger protein 0.0006 0.001 0.0022
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0164 0.373 0.5632
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0082 0.096
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.021 0.2655
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0082 0.096
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0141 0.0233
Plasmodium vivax copper-transporting ATPase, putative 0.0009 0.0082 0.0073
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0516 0.0855
Trypanosoma cruzi cation-transporting ATPase, putative 0.0009 0.0082 0.096
Schistosoma mansoni protein kinase 0.0031 0.0605 0.1352
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0622 0.0928
Loa Loa (eye worm) hypothetical protein 0.0009 0.0082 0.0135
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.021 0.0348
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.021 0.0469
Brugia malayi hypothetical protein 0.0014 0.021 0.0348
Brugia malayi acetyltransferase, GNAT family protein 0.0167 0.3808 0.6308
Schistosoma mansoni sugar transporter 0.0014 0.021 0.0469
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0605 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0614 0.1065
Schistosoma mansoni glucose transport protein 0.0101 0.226 0.5052
Entamoeba histolytica protein kinase, putative 0.0031 0.0605 0.6438
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0605 0.1352
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.059 0.1319
Echinococcus multilocularis copper transporting ATPase 1 0.0009 0.0082 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0141 0.0233
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0141 0.0314
Schistosoma mansoni ferritin 0.0009 0.0082 0.0184
Onchocerca volvulus 0.0014 0.021 0.0369
Loa Loa (eye worm) hypothetical protein 0.0032 0.0622 0.1029
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0614 0.1065
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0407 0.0399
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0407 0.0603
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.0082 0.0972
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0009 0.0082 0.096
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0322 0.3384
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0141 0.0233
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0141 0.0314
Echinococcus multilocularis cation transporting ATPase 13A3 0.0009 0.0082 0.0182
Loa Loa (eye worm) hypothetical protein 0.0025 0.0456 0.0755
Brugia malayi E1-E2 ATPase family protein 0.0009 0.0082 0.0135
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0141 0.0247
Entamoeba histolytica hypothetical protein 0.0023 0.0407 0.43
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0141 0.0247
Chlamydia trachomatis metal transport ATPase 0.0009 0.0082 0.1827
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0141 0.0233
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0009 0.0082 0.0182
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0141 0.0314
Loa Loa (eye worm) hypothetical protein 0.0092 0.2033 0.3367
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0029 0.0036
Schistosoma mansoni hypothetical protein 0.0196 0.4474 1
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0009 0.0082 0.096
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.226 0.5052
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0082 0.096
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0082 0.0182
Trypanosoma brucei P-type H+-ATPase, putative 0.0009 0.0082 0.096
Echinococcus multilocularis cation transporting ATPase 13A1 0.0009 0.0082 0.0182
Onchocerca volvulus 0.0014 0.021 0.0369
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0614 0.799
Schistosoma mansoni ap endonuclease 0.0019 0.0322 0.072
Loa Loa (eye worm) hypothetical protein 0.003 0.059 0.0978
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.2282 0.378
Brugia malayi CXXC zinc finger family protein 0.0029 0.0558 0.0924
Leishmania major hypothetical protein, conserved 0.0029 0.0559 0.7255
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0082 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0262 0.6038 1
Echinococcus granulosus Threonyl tRNA synthetase C 0.0006 0.0009 0.002
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0322 0.3384
Schistosoma mansoni ATPase 0.0009 0.0082 0.0182
Plasmodium vivax hexose transporter 0.0101 0.226 0.2253
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0029 0.0036
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0614 0.799
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0605 0.1002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0636 0.1054
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.059 0.1319
Loa Loa (eye worm) inositol-1 0.0038 0.0767 0.127
Brugia malayi hypothetical protein 0.0014 0.021 0.0348
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0009 0.0082 0.1095
Schistosoma mansoni hypothetical protein 0.0032 0.0636 0.1422
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0767 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.059 0.6278
Echinococcus multilocularis lamin dm0 0.0027 0.0516 0.1154
Giardia lamblia Copper-transporting P-type ATPase 0.0009 0.0082 0.0786
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0006 0.0009 0.002
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0622 0.1389
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0141 0.0233
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.021 0.0348
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.0082 0.1109
Loa Loa (eye worm) hypothetical protein 0.0032 0.0636 0.1054
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0006 0.001 0.0022
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0407 0.091
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.0025
Schistosoma mansoni ferritin 0.0009 0.0082 0.0184
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0605 0.0903
Echinococcus granulosus geminin 0.0196 0.4474 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0767 1
Schistosoma mansoni lamin 0.0027 0.0516 0.1154
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0009 0.0082 0.011
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0322 0.0551
Plasmodium falciparum protein kinase 7 0.0287 0.6615 0.6612
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.021 0.0354
Schistosoma mansoni hypothetical protein 0.007 0.152 0.3398
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0082 0.096
Brugia malayi steroid hormone receptor 0.0011 0.0141 0.0233
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.226 0.5052
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0605 0.1352
Echinococcus multilocularis expressed protein 0.0009 0.0082 0.0184
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.059 0.1319
Brugia malayi PHD-finger family protein 0.0006 0.001 0.0016
Onchocerca volvulus 0.0029 0.0558 0.0979
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0141 0.0233
Brugia malayi Cam kinase protein 1 0.0031 0.0605 0.1002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0322 0.4135
Plasmodium vivax sugar transporter, putative 0.0014 0.021 0.0201
Schistosoma mansoni cation-transporting ATPase 0.0009 0.0082 0.0182
Leishmania major calcium-translocating P-type ATPase 0.0009 0.0082 0.096
Onchocerca volvulus 0.0014 0.021 0.0369
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0127 0.2978
Loa Loa (eye worm) hypothetical protein 0.0262 0.6038 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.001 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0605 0.1352
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0009 0.0082 0.0786
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0407 0.07
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.021 0.0348
Plasmodium vivax SET domain containing protein 0.0006 0.0013 0.0004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0141 0.0233
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0605 0.1352
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0407 0.0674
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0141 0.0233
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.1078 0.1786
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0786
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0127 0.1565
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0786
Echinococcus granulosus solute carrier family 22 0.0014 0.021 0.0469
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0141 0.0247
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0218 0.0362
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0082 0.096
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0407 1
Loa Loa (eye worm) histone methyltransferase 0.001 0.0113 0.0187
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.1078 0.1786
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.059 0.0978
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0009 0.0082 0.0182
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0009 0.0082 0.0786
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0322 0.0314
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0192 0.4392 0.9817
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0605 0.0597
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.059 0.8751
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0009 0.0082 0.096
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Loa Loa (eye worm) hypothetical protein 0.0027 0.0516 0.0855
Echinococcus granulosus cpg binding protein 0.0031 0.0597 0.1335
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0141 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0614 0.1065
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0009 0.0082 0.0073
Brugia malayi hypothetical protein 0.0092 0.2033 0.3367
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0322 0.4716
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0322 0.0551
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.1031 0.1548
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0605 0.0597
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0006 0.0009 0.0014
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Brugia malayi nuclear hormone receptor 0.0011 0.0141 0.0233
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.1031 0.1797
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0009 0.0082 0.096
Schistosoma mansoni cation-transporting atpase worm 0.0009 0.0082 0.0182
Plasmodium vivax cation transporting ATPase, putative 0.0009 0.0082 0.0073
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0141 0.0314
Schistosoma mansoni glycyl-tRNA synthetase 0.0006 0.0009 0.002
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) sugar transporter 0.0014 0.021 0.0348
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0009 0.0082 0.1095
Brugia malayi Sugar transporter family protein 0.0101 0.226 0.3744
Leishmania major copper-transporting ATPase-like protein, putative 0.0009 0.0082 0.096
Mycobacterium ulcerans sugar transporter 0.0014 0.021 0.2655
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0006 0.0015 0.0025
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Onchocerca volvulus 0.0009 0.0082 0.0143
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0141 0.0314
Toxoplasma gondii facilitative glucose transporter GT1 0.0101 0.226 0.3408
Echinococcus granulosus lamin dm0 0.0027 0.0516 0.1154
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0009 0.0082 0.011
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0709 0.9236
Loa Loa (eye worm) acetyltransferase 0.0167 0.3808 0.6308
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0673 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0141 0.0233
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0009 0.0082 0.096
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.021 0.2655
Trypanosoma brucei glucose transporter 2A 0.0031 0.0614 0.799
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0128
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Loa Loa (eye worm) hypothetical protein 0.0029 0.0559 0.0925
Toxoplasma gondii P-type ATPase4, putative 0.0009 0.0082 0.011
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0082 0.0182
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0009 0.0082 0.0182
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0009 0.0082 0.0182
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0322 0.0314
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0141 0.0314
Trypanosoma cruzi P-type H+-ATPase, putative 0.0009 0.0082 0.096
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0164 0.373 0.3724
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0636 0.1054
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0009 0.0082 0.096
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Onchocerca volvulus 0.0014 0.021 0.0369
Loa Loa (eye worm) hypothetical protein 0.0092 0.2033 0.3367
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0767 0.8184
Brugia malayi major facilitator superfamily protein 0.0014 0.021 0.0348
Onchocerca volvulus 0.0014 0.021 0.0369
Toxoplasma gondii sugar transporter ST2 0.0014 0.021 0.0305
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0141 0.0314
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.0082 0.0972
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0614 0.799
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.226 0.5052
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0009 0.0082 0.0182
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0559 0.7255
Echinococcus multilocularis ferritin 0.0009 0.0082 0.0184
Schistosoma mansoni hypothetical protein 0.0101 0.226 0.5052
Leishmania major hypothetical protein, conserved 0.0014 0.021 0.2655
Onchocerca volvulus 0.0014 0.021 0.0369
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0009 0.0082 0.011
Onchocerca volvulus 0.0014 0.021 0.0369
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0141 0.0233
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.226 0.5052
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0141 0.0233
Toxoplasma gondii sugar transporter ST1 0.0014 0.021 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.056 0.1251
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Echinococcus granulosus ferritin 0.0009 0.0082 0.0184
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0082 0.0128
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Schistosoma mansoni protein kinase 0.0031 0.0605 0.1352
Echinococcus granulosus expressed protein 0.0009 0.0082 0.0184
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0009 0.0082 0.011
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0141 0.0314
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0605 0.0597
Loa Loa (eye worm) hypothetical protein 0.0009 0.0082 0.0135
Schistosoma mansoni hypothetical protein 0.0032 0.0636 0.1422
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0009 0.0082 0.0135
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0082 0.096
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Echinococcus granulosus GPCR family 2 0.0032 0.0636 0.1422
Schistosoma mansoni glucose transport protein 0.0101 0.226 0.5052
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.059 0.6278
Brugia malayi Inositol-1 0.0038 0.0767 0.127
Loa Loa (eye worm) hypothetical protein 0.0013 0.0173 0.0286
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0322 0.4135
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0341 0.0585
Trichomonas vaginalis glucose transporter, putative 0.0014 0.021 0.0354
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.021 0.3028
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0009 0.0082 0.1095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0173 0.0286
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0767 0.1714
Trypanosoma cruzi copper-transporting ATPase, putative 0.0009 0.0082 0.096
Treponema pallidum bacterioferrin (TpF1) 0.0009 0.0082 0.2351
Schistosoma mansoni sugar transporter 0.0014 0.021 0.0469
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0767 1
Echinococcus multilocularis musashi 0.0027 0.0516 0.1154
Echinococcus multilocularis solute carrier family 22 0.0014 0.021 0.0469
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0015 0.0034
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0935 1
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0009 0.0082 0.096
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0082 0.0786
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0009 0.0082 0.096
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Schistosoma mansoni ferritin light chain 0.0009 0.0082 0.0184
Loa Loa (eye worm) hypothetical protein 0.0009 0.0082 0.0135
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.226 0.5052
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.021 0.0469
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0614 0.799
Brugia malayi nuclear receptor NHR-88 0.0011 0.0141 0.0233
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.4993 0.827
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0605 0.1002
Toxoplasma gondii sugar transporter ST3 0.0014 0.021 0.0305
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0141 0.0314
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0009 0.0082 0.011
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0071 0.0159
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0009 0.0082 0.096
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0009 0.0082 0.0128
Onchocerca volvulus 0.0014 0.021 0.0369
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0082 0.096
Trypanosoma brucei glucose transporter, putative 0.0031 0.0614 0.799
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0614 0.799
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.1293 0.1944
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) hypothetical protein 0.0013 0.0184 0.0305
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.021 0.0469
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0622 0.1389
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0141 0.0314
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Onchocerca volvulus 0.0014 0.021 0.0369
Onchocerca volvulus 0.0032 0.0622 0.1091
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0082 0.0182
Schistosoma mansoni hypothetical protein 0.0032 0.0636 0.1422
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0605 0.0597
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.058 0.1296
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0009 0.0082 0.1095
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.0025
Onchocerca volvulus 0.0014 0.021 0.0369
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0407 0.5994
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0614 0.799
Toxoplasma gondii P-type ATPase PMA1 0.0009 0.0082 0.011
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0407 0.091
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0605 0.0903
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0082 0.0128
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.0025
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0935 1
Trypanosoma brucei P-type H+-ATPase, putative 0.0009 0.0082 0.096
Brugia malayi hypothetical protein 0.0009 0.0082 0.0135
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0029 0.0036
Schistosoma mansoni lamin 0.0027 0.0516 0.1154
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0009 0.0082 0.0182
Schistosoma mansoni hypothetical protein 0.0032 0.0636 0.1422
Schistosoma mansoni bromodomain containing protein 0.0006 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0006 0.0015 0.0025
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0006 0.0009 0.0014
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0141 0.0233
Echinococcus multilocularis cpg binding protein 0.0031 0.0597 0.1335
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0141 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.021 0.0354
Echinococcus granulosus solute carrier family 22 0.0014 0.021 0.0469
Trypanosoma brucei glucose transporter 1E 0.0031 0.0614 0.799
Trypanosoma cruzi P-type H+-ATPase, putative 0.0009 0.0082 0.096
Echinococcus granulosus cation transporting ATPase 13A3 0.0009 0.0082 0.0182
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0009 0.0082 0.1095
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0082 0.0786
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0141 0.0314
Schistosoma mansoni phosphoserine phosphatase 0.0009 0.0082 0.0182
Echinococcus granulosus glycyl tRNA synthetase 0.0006 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0141 0.0233
Echinococcus multilocularis GPCR, family 2 0.0032 0.0636 0.1422
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0605 0.1352
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0636 0.1422
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0141 0.0314
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0009 0.0082 0.096
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0082 0.0182
Echinococcus multilocularis General substrate transporter 0.0087 0.1925 0.4303
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0605 0.0597
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0071 0.0159
Plasmodium vivax CDK-related protein kinase 6, putative 0.0431 1 1
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.021 0.2655
Plasmodium vivax calcium-transporting ATPase, putative 0.0009 0.0082 0.0073
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.021 0.0354
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0141 0.0314
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.226 0.5052
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0082 0.0786
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0559 0.0832
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0141 0.0233
Schistosoma mansoni ferritin light chain 0.0009 0.0082 0.0184
Echinococcus multilocularis cation transporting atpase worm 0.0009 0.0082 0.0182
Schistosoma mansoni sugar transporter 0.0014 0.021 0.0469
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Echinococcus multilocularis geminin 0.0196 0.4474 1
Brugia malayi hypothetical protein 0.0029 0.0559 0.0925
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0322 0.072
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0167 0.3808 0.8513
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0327 0.4786
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0605 0.1352
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0709 0.106
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0322 0.0534
Plasmodium falciparum mitogen-activated protein kinase 2 0.0164 0.373 0.3724
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0009 0.0082 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0141 0.0233
Brugia malayi ecdysteroid receptor 0.0011 0.0141 0.0233
Echinococcus granulosus solute carrier family 22 0.0014 0.021 0.0469
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0614 0.1065
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.056 0.1251
Plasmodium falciparum hexose transporter 0.0101 0.226 0.2253
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0407 0.091
Onchocerca volvulus 0.0014 0.021 0.0369
Echinococcus granulosus lamin 0.0027 0.0516 0.1154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0141 0.0233
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0767 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0322 0.4135
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0006 0.0009 0.0014
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0709 0.9236
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0082 0.0182
Onchocerca volvulus 0.0248 0.5698 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0141 0.0233
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0029 0.0036
Echinococcus granulosus zinc finger protein 0.0006 0.001 0.0022
Leishmania major P-type H -ATPase, putative 0.0009 0.0082 0.096
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.1078 0.241
Trichomonas vaginalis ferritin, putative 0.0009 0.0082 0.013
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.021 0.2655
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0407 0.5254
Echinococcus multilocularis solute carrier family 22 0.0014 0.021 0.0469
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Schistosoma mansoni hypothetical protein 0.0013 0.0181 0.0405
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0141 0.0233
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0141 0.0314
Trypanosoma brucei cation-transporting ATPase, putative 0.0009 0.0082 0.096
Schistosoma mansoni glucose transporter 0.0014 0.021 0.0469
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.2282 0.378
Leishmania major glucose transporter, lmgt3 0.0031 0.0614 0.799
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0767 0.1332
Schistosoma mansoni coup transcription factor 0.0011 0.0141 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354
Onchocerca volvulus 0.0014 0.021 0.0369
Trypanosoma brucei sugar transporter, putative 0.0014 0.021 0.2655
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0181 0.0405
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0322 0.4135
Loa Loa (eye worm) hypothetical protein 0.0027 0.0505 0.0836
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0127 0.3784
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0559 0.7255
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0614 0.1065
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0009 0.0082 0.0135
Brugia malayi E1-E2 ATPase family protein 0.0009 0.0082 0.0135
Giardia lamblia Hexose transporter 0.0014 0.021 0.2173
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0622 0.1389
Trypanosoma cruzi sugar transporter, putative 0.0014 0.021 0.2655
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.059 0.0978
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0327 0.4786
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0141 0.0314
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.021 0.2655
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.021 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0029 0.0036
Brugia malayi glycyl-tRNA synthetase 0.0006 0.0009 0.0014
Brugia malayi Pre-SET motif family protein 0.0032 0.0622 0.1029
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Schistosoma mansoni eyes absent homolog 0.0092 0.2033 0.4544
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0141 0.0233
Trypanosoma cruzi glucose transporter, putative 0.0014 0.021 0.2655
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0141 0.0314
Toxoplasma gondii exonuclease III APE 0.0019 0.0322 0.0474
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0009 0.0082 0.096
Plasmodium vivax SET domain protein, putative 0.0032 0.0622 0.0613
Schistosoma mansoni type V p-type atpase isoform 0.0009 0.0082 0.0182
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0141 0.0314
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Loa Loa (eye worm) hypothetical protein 0.0014 0.021 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0141 0.0233
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0605 0.1352
Trichomonas vaginalis helicase, putative 0.0007 0.0029 0.0036
Brugia malayi Pre-SET motif family protein 0.0218 0.4993 0.827
Schistosoma mansoni hypothetical protein 0.0196 0.4474 1
Echinococcus granulosus solute carrier family 22 0.0014 0.021 0.0469
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0636 0.1422
Leishmania major glucose transporter, lmgt1 0.0031 0.0614 0.799
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0009 0.0082 0.1095
Echinococcus multilocularis zinc finger protein 0.0006 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0009 0.0082 0.0135
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0636 0.1054
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0141 0.0314
Treponema pallidum hypothetical protein 0.0009 0.0082 0.2322
Plasmodium falciparum copper-transporting ATPase 0.0009 0.0082 0.0073
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0407 0.5254
Echinococcus multilocularis glycyl tRNA synthetase 0.0006 0.0009 0.002
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0605 0.1002
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.021 0.0201
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0101 0.226 0.5052
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.021 0.0354
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.1078 0.241
Schistosoma mansoni ferritin 0.0009 0.0082 0.0184
Trichomonas vaginalis sugar transporter, putative 0.0014 0.021 0.0354

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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