Detailed information for compound 1574207

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 628.75 | Formula: C35H48O10
  • H donors: 1 H acceptors: 4 LogP: 3.41 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCO[C@@H]1O[C@H]2C[C@H](C(=C2[C@]2([C@H](C1)[C@@]1(C)[C@@H](O)C[C@H]([C@@]3([C@@H]1[C@H]([C@H]2OC(=O)/C(=C/C)/C)OC3)C)OC(=O)C)C)C)C1=CCOC1=O
  • InChi: 1S/C35H48O10/c1-9-17(3)31(38)45-30-28-29-33(6,16-42-28)25(43-19(5)36)15-24(37)34(29,7)23-14-26(40-10-2)44-22-13-21(20-11-12-41-32(20)39)18(4)27(22)35(23,30)8/h9,11,21-26,28-30,37H,10,12-16H2,1-8H3/b17-9+/t21-,22+,23-,24+,25-,26-,28-,29+,30-,33-,34+,35-/m1/s1
  • InChiKey: XKOPCBHBBCCNEY-OOQJZCITSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0078 0.0078
Treponema pallidum phosphoglycerate kinase 0.0192 0.1001 1
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0213 0.2118
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0078 0.0078
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0075 0.0075
Trypanosoma cruzi ISWI complex protein 0.0018 0.0027 0.0057
Echinococcus multilocularis caspase 8 0.0059 0.0255 0.0255
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0213 0.2077
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Brugia malayi Niemann-Pick C1 protein precursor 0.0111 0.0547 0.0546
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0114 0.0113
Brugia malayi Protein kinase domain containing protein 0.0018 0.0026 0.0026
Onchocerca volvulus 0.0027 0.0078 0.0272
Onchocerca volvulus 0.0027 0.0078 0.0272
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0078 0.0078
Trypanosoma brucei metacaspase 0.0059 0.0255 0.0683
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0078 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0423 0.1143
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0614 0.0614
Echinococcus multilocularis GPCR, family 2 0.0033 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0129 0.0648 0.0647
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0078 0.0078
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0075 0.0075
Brugia malayi follicle stimulating hormone receptor 0.0027 0.0078 0.0078
Schistosoma mansoni amine GPCR 0.0027 0.0078 0.0078
Schistosoma mansoni biogenic amine (5HT) receptor 0.0773 0.425 0.4249
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0161 0.0826 0.2892
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0135 0.0134
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0006 0.0051
Echinococcus multilocularis SAM and MBT domain containing protein 0.0161 0.0826 0.0825
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0078 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0381 0.1026
Trypanosoma brucei metacaspase MCA3 0.0059 0.0255 0.0683
Trypanosoma brucei unspecified product 0.0066 0.0299 0.0803
Brugia malayi MH2 domain containing protein 0.0123 0.0614 0.0614
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0078 0.0078
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni zinc finger protein 0.0026 0.0073 0.0072
Mycobacterium ulcerans glutaminase 0.0604 0.3303 1
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0095 0.0244
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0322 0.0865
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0066 0.0295 0.0294
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.0407 0.0406
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0255 0.2545
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0018
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0114 0.0113
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0015 0.0013 0.0042
Echinococcus multilocularis Ankyrin 0.0013 0.0001 0.0001
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0078 0.0078
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0344 0.0926
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Trypanosoma brucei DNA polymerase IV, putative 0.0141 0.0713 0.1937
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0075 0.0075
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0078 0.0078
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0095 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0075 0.0075
Onchocerca volvulus 0.0027 0.0078 0.0272
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0078 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0056 0.0055
Brugia malayi Cathepsin L-like precursor 0.0015 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0086 0.0407 0.0406
Echinococcus granulosus lamin 0.0024 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0192 0.1001 0.2726
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0159 0.0159
Schistosoma mansoni neuropeptide receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.046 0.2498 0.2497
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0075 0.0075
Entamoeba histolytica deoxycytidyl transferase, putative 0.0096 0.0466 0.4627
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0078 0.0078
Echinococcus granulosus carbonic anhydrase 0.0129 0.0648 0.0647
Loa Loa (eye worm) hypothetical protein 0.05 0.2721 0.2721
Echinococcus granulosus caspase 8 0.0059 0.0255 0.0255
Brugia malayi hypothetical protein 0.0014 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Echinococcus multilocularis phosphoglycerate kinase 1 0.0192 0.1001 0.1001
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0238 0.1257 0.1257
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0013 0.0001 0.0001
Echinococcus multilocularis zinc finger protein 0.0026 0.0073 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0075 0.0075
Schistosoma mansoni glutaminase 0.0604 0.3303 0.3303
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0163 0.0841 0.2944
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0151 0.1455
Loa Loa (eye worm) RecQ helicase 0.0019 0.0036 0.0035
Entamoeba histolytica hypothetical protein 0.0037 0.0135 0.1293
Leishmania major hypothetical protein, conserved 0.0051 0.0213 0.0566
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) carbonic anhydrase 3 0.0238 0.1257 0.1257
Onchocerca volvulus 0.0015 0.0013 0.0042
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0066 0.0295 0.0877
Brugia malayi hypothetical protein 0.0014 0.0006 0.0005
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0075 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Echinococcus multilocularis sex peptide receptor 0.0027 0.0078 0.0078
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0129 0.0648 0.0647
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0013 0.0001 0.000000019668
Schistosoma mansoni ankyrin 23/unc44 0.0013 0.0001 0.000000019668
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0151 0.0397
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0006 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0015 0.0013 0.0067
Schistosoma mansoni hypothetical protein 0.0984 0.5432 0.5431
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Loa Loa (eye worm) hypothetical protein 0.0635 0.3476 0.3476
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0327 0.0327
Loa Loa (eye worm) mbt repeat family protein 0.0161 0.0826 0.0825
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0075 0.0075
Schistosoma mansoni neuropeptide receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0078 0.0078
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0033 0.0114 0.0113
Brugia malayi Cathepsin L-like precursor 0.0015 0.0013 0.0012
Trypanosoma cruzi cruzipain precursor, putative 0.0058 0.0251 0.0672
Leishmania major cathepsin L-like protease 0.0015 0.0013 0.0018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0078 0.0078
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0013 0.0042
Brugia malayi Cathepsin L-like precursor 0.0015 0.0013 0.0012
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0078 0.0078
Schistosoma mansoni lamin 0.0024 0.0064 0.0064
Trypanosoma cruzi major cysteine proteinase, putative 0.0045 0.0182 0.0482
Echinococcus granulosus sex peptide receptor 0.0027 0.0078 0.0078
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0159 0.159
Loa Loa (eye worm) hypothetical protein 0.0072 0.033 0.0329
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0004
Giardia lamblia DNA damage repair protein 0.003 0.0095 0.0894
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0019 0.005
Trypanosoma brucei DNA polymerase IV, putative 0.0155 0.0795 0.2161
Entamoeba histolytica hypothetical protein 0.0037 0.0135 0.1293
Echinococcus multilocularis serotonin receptor 0.0773 0.425 0.4249
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0078 0.0078
Entamoeba histolytica cysteine protease, putative 0.0015 0.0013 0.0067
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0344 0.0343
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0739 0.0739
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0096 0.0466 0.0466
Brugia malayi Serotonin receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis Sentrin-specific protease, putative 0.0066 0.0295 0.0877
Schistosoma mansoni amine GPCR 0.0027 0.0078 0.0078
Giardia lamblia Histone acetyltransferase GCN5 0.0035 0.0126 0.1205
Brugia malayi ecdysteroid receptor 0.0026 0.0075 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0095 0.0244
Trypanosoma cruzi metacaspase 5, putative 0.0059 0.0255 0.0683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Brugia malayi Bromodomain containing protein 0.0048 0.0194 0.0193
Loa Loa (eye worm) hypothetical protein 0.0153 0.0781 0.078
Schistosoma mansoni histamine h1 receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0547 0.0546
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0327 0.0327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0056 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0381 0.1026
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0169 0.0168
Echinococcus multilocularis cathepsin L cysteine protease 0.0015 0.0013 0.0012
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0019 0.0035
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0322 0.0865
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0739 0.0739
Schistosoma mansoni biogenic amine receptor 0.0027 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0075 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0075 0.0075
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0078 0.0078
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0006 0.0005
Brugia malayi small heat shock protein 0.0524 0.2857 0.2856
Schistosoma mansoni myosin xvIII 0.0027 0.0078 0.0078
Plasmodium vivax vivapain-2 0.0015 0.0013 0.0117
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0064
Onchocerca volvulus 0.0027 0.0078 0.0272
Schistosoma mansoni ap endonuclease 0.004 0.0151 0.015
Loa Loa (eye worm) hypothetical protein 0.0058 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0641 0.3511 0.3511
Brugia malayi Melatonin receptor type 1A 0.0027 0.0078 0.0078
Brugia malayi Uncoordinated protein 44 0.0013 0.0001 0.000000019668
Echinococcus multilocularis polycomb protein SCMH1 0.0161 0.0826 0.0825
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.0283 0.0282
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0075 0.0075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0151 0.0174
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0381 0.1026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0078 0.0078
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1802 1 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0516 0.0515
Schistosoma mansoni lozenge 0.0063 0.0278 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0015 0.0013 0.002
Loa Loa (eye worm) TAR-binding protein 0.0071 0.0327 0.0327
Trypanosoma brucei metacaspase MCA2 0.0059 0.0255 0.0683
Schistosoma mansoni hypothetical protein 0.0023 0.0056 0.0055
Echinococcus multilocularis musashi 0.0024 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.0466 0.0466
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0078 0.0078
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0151 0.0439
Echinococcus multilocularis bloom syndrome protein 0.0019 0.0036 0.0035
Loa Loa (eye worm) runx1 0.0063 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0161 0.0826 0.2892
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0015 0.0013 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0064 0.0064
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0129 0.0648 0.0647
Brugia malayi Muscleblind-like protein 0.0635 0.3476 0.3476
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0129 0.0648 0.0647
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0078 0.0078
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0614 0.0614
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0019 0.0018
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0078 0.0078
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.0327 0.0327
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.0327 0.0327
Onchocerca volvulus 0.0027 0.0078 0.0272
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0151 0.0397
Loa Loa (eye worm) glutaminase 0.0604 0.3303 0.3303
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0013 0.0012
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0078 0.0078
Brugia malayi Dopamine receptor protein 1 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0018
Echinococcus multilocularis tar DNA binding protein 0.0071 0.0327 0.0327
Schistosoma mansoni hypothetical protein 0.0033 0.0114 0.0113
Echinococcus granulosus GPCR family 2 0.0033 0.0114 0.0113
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0075 0.0075
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0114 0.0113
Echinococcus granulosus bloom syndrome protein 0.0019 0.0036 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0667 0.3657 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0452 0.1222
Leishmania major cathepsin L-like protease 0.0058 0.0251 0.0672
Plasmodium falciparum metacaspase 1 0.0059 0.0255 0.2507
Brugia malayi steroid hormone receptor 0.0026 0.0075 0.0075
Brugia malayi Dopamine receptor protein 2 0.0027 0.0078 0.0078
Echinococcus granulosus caspase 0.0059 0.0255 0.0255
Leishmania major cathepsin L-like protease 0.0015 0.0013 0.0018
Schistosoma mansoni hypothetical protein 0.0033 0.0114 0.0113
Onchocerca volvulus 0.0027 0.0078 0.0272
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0213 0.0566
Leishmania major cathepsin L-like protease 0.0015 0.0013 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Echinococcus granulosus cathepsin L cysteine proteinase 0.0015 0.0013 0.0012
Loa Loa (eye worm) ctsf protein 0.0015 0.0013 0.0012
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0344 0.0343
Schistosoma mansoni hypothetical protein 0.0046 0.0184 0.0183
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni blooms syndrome DNA helicase 0.0015 0.0013 0.0013
Echinococcus multilocularis caspase 2 0.0059 0.0255 0.0255
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0183 0.095 0.0949
Brugia malayi GnHR receptor homolog 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0192 0.1001 0.1001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0078 0.0078
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0095 0.0244
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0014 0.0006 0.0005
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0075 0.0075
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0019 0.0018
Brugia malayi nuclear receptor NHR-88 0.0026 0.0075 0.0075
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0078 0.0078
Brugia malayi intermediate filament protein 0.0024 0.0064 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0075 0.0075
Brugia malayi PHD-finger family protein 0.0032 0.0107 0.0106
Trichomonas vaginalis DNA polymerase eta, putative 0.0155 0.0795 0.2392
Mycobacterium tuberculosis Conserved hypothetical protein 0.0351 0.1892 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0078 0.0078
Brugia malayi nuclear receptor RXR 0.0014 0.0006 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0532 0.2901 0.29
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0015 0.0013 0.0012
Echinococcus granulosus biogenic amine 5HT receptor 0.0415 0.2249 0.2248
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0255 0.0757
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0078 0.0078
Onchocerca volvulus Cell death protein 3 homolog 0.0059 0.0255 0.0893
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0053 0.0223 0.0595
Echinococcus multilocularis 0.0014 0.0006 0.0005
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi G-protein coupled receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0159 0.0465
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0013 0.0067
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0019 0.0185
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0183 0.095 0.0949
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus carbonic anhydrase II 0.0238 0.1257 0.1257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0667 0.3657 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Mycobacterium ulcerans DNA polymerase IV 0.0155 0.0795 0.2181
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0078 0.0078
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0135 0.0134
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0019 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0095 0.0244
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.0075 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Schistosoma mansoni biogenic amine (5HT) receptor 0.0415 0.2249 0.2248
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0075 0.0075
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0006 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0327 0.0327
Echinococcus multilocularis serotonin receptor 0.0773 0.425 0.4249
Schistosoma mansoni hypothetical protein 0.0033 0.0114 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0075 0.0075
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0066 0.0295 0.0294
Schistosoma mansoni hypothetical protein 0.0129 0.0648 0.0647
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0046 0.0184 0.0183
Trypanosoma cruzi metacaspase, putative 0.0059 0.0255 0.0683
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0251 0.0672
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0075 0.0075
Schistosoma mansoni neuropeptide receptor 0.0027 0.0078 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0048 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0255 0.0757
Mycobacterium tuberculosis Conserved hypothetical protein 0.0096 0.0466 0.2429
Onchocerca volvulus 0.0027 0.0078 0.0272
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0075 0.0075
Brugia malayi neuropeptide F receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0135 0.0134
Echinococcus granulosus cathepsin l1 0.0015 0.0013 0.0012
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0078 0.0272
Trypanosoma brucei unspecified product 0.0066 0.0299 0.0803
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0193 0.0193
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0013 0.0012
Brugia malayi nuclear hormone receptor 0.0026 0.0075 0.0075
Echinococcus granulosus fmrfamide receptor 0.0027 0.0078 0.0078
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0094 0.0452 0.1222
Loa Loa (eye worm) hypothetical protein 0.0111 0.0547 0.0546
Brugia malayi Dopamine receptor 0.0027 0.0078 0.0078
Trypanosoma cruzi metacaspase 5, putative 0.0059 0.0255 0.0683
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0075 0.0075
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0019 0.0185
Leishmania major cathepsin L-like protease 0.0015 0.0013 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Trypanosoma brucei DNA polymerase eta, putative 0.0153 0.0781 0.2123
Echinococcus granulosus muscleblind protein 0.0635 0.3476 0.3476
Echinococcus granulosus cathepsin l cysteine peptidase 0.0015 0.0013 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0516 0.0515
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0078 0.0078
Echinococcus granulosus phosphoglycerate kinase 1 0.0192 0.1001 0.1001
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) glutaminase 2 0.0604 0.3303 0.3303
Brugia malayi hypothetical protein 0.05 0.2721 0.2721
Schistosoma mansoni myelin transcription factor 1 myt1 0.0183 0.095 0.0949
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0014 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Schistosoma mansoni hypothetical protein 0.0014 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0075 0.0262
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0739 0.0739
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0036 0.0091
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus SAM and MBT domain containing protein 0.0161 0.0826 0.0825
Toxoplasma gondii hypothetical protein 0.0129 0.0648 0.647
Schistosoma mansoni biogenic amine receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0095 0.094
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0044 0.0176 0.1762
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0641 0.3511 0.3511
Leishmania major DNA polymerase eta, putative 0.0086 0.0409 0.1105
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Leishmania major cathepsin L-like protease 0.0058 0.0251 0.0672
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis dna polymerase eta 0.0153 0.0781 0.078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0066 0.0296 0.296
Schistosoma mansoni adenoreceptor 0.0027 0.0078 0.0078
Schistosoma mansoni caspase-3 (C14 family) 0.0059 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0051 0.0213 0.0212
Plasmodium vivax vivapain-2 0.0015 0.0013 0.0117
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0066 0.0295 0.0877
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0192 0.1001 0.2726
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0078 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0066 0.0296 0.0296
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0344 0.0343
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0078 0.0078
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0192 0.1001 0.5
Loa Loa (eye worm) MBCTL1 0.0183 0.095 0.0949
Echinococcus multilocularis somatostatin receptor 0.0027 0.0078 0.0078
Schistosoma mansoni sex comb on midleg homolog 0.0161 0.0826 0.0825
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0075 0.0075
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0094 0.0452 0.1222
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0067 0.0301 0.0301
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0095 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0066 0.0296 0.0296
Trypanosoma brucei ISWI complex protein 0.0018 0.0027 0.0057
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0013 0.0012
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0129 0.0648 0.0647
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0213 0.0566
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0075 0.0075
Loa Loa (eye worm) Ulp1 protease 0.0066 0.0295 0.0294
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1802 1 1
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0078 0.0078
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0075 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Echinococcus multilocularis cathepsin L cysteine protease 0.0015 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni phosphoglycerate kinase 0.0192 0.1001 0.1001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0316 0.1693 0.462
Schistosoma mansoni hypothetical protein 0.0018 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0062 0.0061
Schistosoma mansoni hypothetical protein 0.0024 0.0061 0.0061
Leishmania major phosphoglycerate kinase C, glycosomal 0.0192 0.1001 0.2726
Echinococcus granulosus histone lysine methyltransferase setb 0.0086 0.0407 0.0406
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0169 0.0168
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0238 0.1257 0.3427
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0074 0.0073
Onchocerca volvulus 0.0015 0.0013 0.0042
Brugia malayi Death domain containing protein 0.0013 0.0001 0.000000019668
Schistosoma mansoni bromodomain containing protein 0.0077 0.0356 0.0355
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0095 0.0244
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0078 0.0078
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0344 0.3397
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0322 0.0865
Schistosoma mansoni terminal deoxycytidyl transferase 0.0096 0.0466 0.0466
Loa Loa (eye worm) cysteine protease 0.0015 0.0013 0.0012
Mycobacterium ulcerans DNA polymerase IV 0.0155 0.0795 0.2181
Brugia malayi acetyltransferase, GNAT family protein 0.0134 0.0678 0.0677
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.0036 0.0091
Plasmodium falciparum cysteine proteinase falcipain 3 0.0015 0.0013 0.0067
Brugia malayi sulfakinin receptor protein 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0027 0.0078 0.0272
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0213 0.2125
Echinococcus granulosus caspase 2 0.0059 0.0255 0.0255
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0238 0.1257 0.1257
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0524 0.2857 0.2856
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0053 0.0222 0.0221
Echinococcus multilocularis histone acetyltransferase MYST2 0.0183 0.095 0.0949
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0059 0.0255 0.2551
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Trypanosoma brucei DNA polymerase IV, putative 0.0155 0.0795 0.2161
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni carbonic anhydrase-related 0.0129 0.0648 0.0647
Onchocerca volvulus 0.0523 0.2853 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0089 0.0423 0.1143
Echinococcus granulosus polycomb protein SCMH1 0.0161 0.0826 0.0825
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0086 0.0409 0.409
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Echinococcus granulosus hypothetical protein 0.0027 0.0078 0.0078
Plasmodium falciparum phosphoglycerate kinase 0.0192 0.1001 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Brugia malayi hypothetical protein 0.0163 0.0841 0.084
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0006 0.0005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0075 0.0075
Trypanosoma cruzi metacaspase, putative 0.0059 0.0255 0.0683
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0344 0.0926
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0059 0.0255 0.0255
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0516 0.0515
Leishmania major mitochondrial DNA polymerase beta 0.0667 0.3657 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0129 0.0648 0.0647
Brugia malayi hypothetical protein 0.0033 0.0112 0.0111
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0013 0.0018
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0151 0.1455
Brugia malayi putative neuropeptide receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0332 0.0332
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0064 0.0064
Echinococcus granulosus geminin 0.0532 0.2901 0.29
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0111 0.0547 0.5435
Schistosoma mansoni hypothetical protein 0.0532 0.2901 0.29
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0096 0.0466 0.0466
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Schistosoma mansoni hypothetical protein 0.0037 0.0135 0.0134
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0014 0.0006 0.0005
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0017 0.0023 0.0169
Plasmodium falciparum histone acetyltransferase GCN5 0.0035 0.0126 0.1205
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0773 0.425 0.4249
Brugia malayi G-protein coupled receptor 0.0027 0.0078 0.0078
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0014 0.0006 0.006
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0238 0.1257 0.1257
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0066 0.0295 0.0877
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0255 0.0757
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0074 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0075 0.0075
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0078 0.0078
Entamoeba histolytica phosphoglycerate kinase, putative 0.0192 0.1001 1
Echinococcus granulosus CTD small phosphatase protein like 0.0014 0.0006 0.0005
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0027 0.0078 0.0272
Schistosoma mansoni sex comb on midleg homolog 0.0161 0.0826 0.0825
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0129 0.0648 0.0647
Brugia malayi Phosphoglycerate kinase 0.0192 0.1001 0.1001
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0006 0.0005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0078 0.0078
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0075 0.0075
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis protein patched 0.0048 0.0193 0.0193
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0046 0.0184 0.0183
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Trypanosoma cruzi DNA polymerase eta, putative 0.0086 0.0409 0.1105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0027 0.0078 0.0272
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0074 0.0073
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0238 0.1257 0.1257
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Trypanosoma cruzi ISWI complex protein 0.0018 0.0027 0.0057
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0111 0.0548 0.1484
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0327 0.0327
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0095 0.0894
Schistosoma mansoni hypothetical protein 0.0072 0.033 0.0329
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0516 0.0515
Onchocerca volvulus 0.0027 0.0078 0.0272
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0739 0.0739
Trypanosoma cruzi DNA polymerase eta, putative 0.0153 0.0781 0.2123
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0095 0.0244
Brugia malayi hypothetical protein 0.0051 0.0213 0.0212
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0033 0.0114 0.0113
Schistosoma mansoni microtubule-associated protein tau 0.0626 0.3427 0.3427
Trypanosoma brucei unspecified product 0.0141 0.0713 0.1937
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0075 0.0075
Brugia malayi glutaminase DH11.1 0.0604 0.3303 0.3303
Giardia lamblia DINP protein human, muc B family 0.0111 0.0548 0.5446
Brugia malayi RNA binding protein 0.0071 0.0327 0.0327
Echinococcus granulosus serotonin receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0129 0.0648 0.0647
Onchocerca volvulus Cathepsin F homolog 0.0015 0.0013 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Entamoeba histolytica hypothetical protein 0.0037 0.0135 0.1293
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0095 0.0244
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0134 0.0678 0.0677
Echinococcus granulosus orexin receptor type 2 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus g protein coupled receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0015 0.0013 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0255 0.0757
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0332 0.0332
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0213 0.2077
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0078 0.0078
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0013 0.0067
Brugia malayi hypothetical protein 0.0037 0.0135 0.0134
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0161 0.0826 0.0825
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0019 0.0018
Schistosoma mansoni intermediate filament proteins 0.0024 0.0064 0.0064
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0193 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Trypanosoma brucei phosphoglycerate kinase 0.0192 0.1001 0.2726
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0059 0.0255 0.2551
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus granulosus carbonic anhydrase 0.0129 0.0648 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0255 0.0757
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0078 0.0078
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0151 0.0439
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) fibroinase 0.0015 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Schistosoma mansoni amine GPCR 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0129 0.0648 0.0647
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0075 0.0075
Echinococcus granulosus microtubule associated protein 2 0.0626 0.3427 0.3427
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0059 0.0255 0.0255
Plasmodium vivax phosphoglycerate kinase, putative 0.0192 0.1001 1
Echinococcus granulosus neuropeptide receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0059 0.0255 0.0255
Trypanosoma cruzi metacaspase, putative 0.0059 0.0255 0.0683
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0078 0.0078
Chlamydia trachomatis phosphoglycerate kinase 0.0192 0.1001 0.5
Echinococcus multilocularis Niemann Pick C1 protein 0.0158 0.0813 0.0812
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0094 0.0452 0.1222
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0344 0.0926
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0078 0.0078
Trypanosoma brucei phosphoglycerate kinase 0.007 0.0322 0.0865
Echinococcus multilocularis cysteine protease 0.0015 0.0013 0.0012
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0192 0.1001 0.3018
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0075 0.0075
Leishmania major DNA polymerase kappa, putative 0.0111 0.0548 0.1484
Onchocerca volvulus 0.05 0.2721 0.9538
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0075 0.0075
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0078 0.0078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0739 0.0739
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0192 0.1001 1
Echinococcus multilocularis caspase 0.0059 0.0255 0.0255
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Loa Loa (eye worm) acetyltransferase 0.0134 0.0678 0.0677
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0415 0.2249 0.2248
Toxoplasma gondii cathepsin CPL 0.0015 0.0013 0.0126
Schistosoma mansoni amine GPCR 0.0027 0.0078 0.0078
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0344 0.0343
Onchocerca volvulus 0.0015 0.0013 0.0042
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0322 0.0865
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0013 0.0001 0.000000019668
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0078 0.0078
Toxoplasma gondii exonuclease III APE 0.004 0.0151 0.1506
Onchocerca volvulus 0.0024 0.0064 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.1802 1 1
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0075 0.0262
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0059 0.0255 0.0255
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0075 0.0075
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0078 0.0078
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0159 0.1583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Echinococcus multilocularis protein dispatched 1 0.0054 0.0231 0.023
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0075 0.0075
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0095 0.0948
Onchocerca volvulus 0.0248 0.1312 0.4597
Schistosoma mansoni biogenic amine receptor 0.0027 0.0078 0.0078
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0344 0.0343
Trypanosoma brucei phosphoglycerate kinase, putative 0.007 0.0322 0.0865
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0061 0.0061
Brugia malayi Cathepsin L-like precursor 0.0015 0.0013 0.0012
Schistosoma mansoni carbonic anhydrase-related 0.0129 0.0648 0.0647
Echinococcus multilocularis geminin 0.0532 0.2901 0.29
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0038 0.0038
Leishmania major carbonic anhydrase-like protein 0.0238 0.1257 0.3427
Onchocerca volvulus 0.0027 0.0078 0.0272
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0322 0.0865
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Leishmania major DNA polymerase kappa, putative 0.003 0.0095 0.0244
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Schistosoma mansoni DNA polymerase eta 0.0153 0.0781 0.078
Echinococcus granulosus Niemann Pick C1 protein 0.0158 0.0813 0.0812
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0316 0.1693 0.462
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0078 0.0078
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0316 0.1693 0.462
Echinococcus granulosus somatostatin receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0078 0.0078
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0238 0.1257 0.1257
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0078 0.0078
Echinococcus multilocularis microtubule associated protein 2 0.0626 0.3427 0.3427
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0096 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi Pax transcription factor protein 2 0.0248 0.1312 0.1311
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni caspase-7 (C14 family) 0.0059 0.0255 0.0255
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.006 0.006
Echinococcus granulosus dna polymerase kappa 0.0155 0.0795 0.0794
Brugia malayi neuropeptide F receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0193 0.0193
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0114 0.0113
Echinococcus granulosus g protein coupled receptor 0.0027 0.0078 0.0078
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0155 0.0795 0.2392
Echinococcus granulosus Ankyrin 0.0013 0.0001 0.0001
Echinococcus granulosus allatostatin A receptor 0.0027 0.0078 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0327 0.0327
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0151 0.0752
Brugia malayi ImpB/MucB/SamB family protein 0.0153 0.0781 0.078
Schistosoma mansoni lamin 0.0024 0.0064 0.0064
Trypanosoma brucei metacaspase 5, putative 0.0059 0.0255 0.0683
Schistosoma mansoni opsin-like receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0635 0.3476 0.3476
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.007 0.0322 0.0865
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0078 0.0078
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0112 0.0556 0.0556
Echinococcus multilocularis cysteine protease 0.0015 0.0013 0.0012
Loa Loa (eye worm) RNA binding protein 0.0071 0.0327 0.0327
Leishmania major cathepsin L-like protease 0.0015 0.0013 0.0018
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0111 0.0548 0.2861
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0078 0.0078
Echinococcus multilocularis lamin 0.0024 0.0064 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Loa Loa (eye worm) hypothetical protein 0.0089 0.0423 0.0423
Echinococcus granulosus g protein coupled receptor 0.0027 0.0078 0.0078
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0192 0.1001 0.5268
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0192 0.1001 1
Brugia malayi polk-prov protein 0.0089 0.0423 0.0423
Echinococcus multilocularis muscleblind protein 1 0.0635 0.3476 0.3476
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0027 0.0078 0.0272
Echinococcus granulosus intermediate filament protein 0.0024 0.0064 0.0064
Plasmodium vivax metacaspase 1, putative 0.0059 0.0255 0.2545
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0151 0.015
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0151 0.1499
Schistosoma mansoni phosphoglycerate kinase 0.0192 0.1001 0.1001
Schistosoma mansoni patched 1 0.0048 0.0193 0.0193
Onchocerca volvulus 0.0015 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0108 0.0529 0.5286
Trypanosoma brucei Metacaspase-4 0.0059 0.0255 0.0683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0075 0.0075
Brugia malayi isocitrate dehydrogenase 0.0016 0.0019 0.0018
Schistosoma mansoni carbonic anhydrase 0.0129 0.0648 0.0647
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0739 0.0739
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Echinococcus granulosus neuropeptide receptor 0.0027 0.0078 0.0078
Brugia malayi mbt repeat family protein 0.0161 0.0826 0.0825
Plasmodium falciparum metacaspase-like protein 0.0059 0.0255 0.2507
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0015 0.0013 0.0067
Echinococcus multilocularis sentrin specific protease 8 0.0066 0.0295 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Echinococcus multilocularis lamin dm0 0.0024 0.0064 0.0064
Echinococcus granulosus biogenic amine 5HT receptor 0.0773 0.425 0.4249
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0006 0.0005
Onchocerca volvulus 0.0027 0.0078 0.0272
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0059 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni coup transcription factor 0.0026 0.0075 0.0075
Brugia malayi ORL1-like opioid receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0078 0.0078
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0038 0.0038
Brugia malayi Bromodomain containing protein 0.009 0.0432 0.0431
Echinococcus multilocularis muscleblind protein 0.0635 0.3476 0.3476
Leishmania major DNA damage repair protein, putative 0.003 0.0095 0.0244
Echinococcus multilocularis carbonic anhydrase 0.0129 0.0648 0.0647
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0013 0.0042
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0059 0.0255 0.0255
Brugia malayi Cathepsin L-like precursor 0.0015 0.0013 0.0012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0151 0.0397
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0078 0.0078
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0078 0.0078
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Onchocerca volvulus 0.0027 0.0078 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Echinococcus multilocularis carbonic anhydrase 0.0129 0.0648 0.0647
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0667 0.3657 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0192 0.1001 0.3018
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0078 0.0078
Onchocerca volvulus 0.0027 0.0078 0.0272
Onchocerca volvulus 0.0026 0.0075 0.0262
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0134 0.0678 0.0677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0251 0.0672
Echinococcus multilocularis Protein lozenge 0.0063 0.0278 0.0278
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0075 0.0075
Echinococcus granulosus sentrin specific protease 8 0.0066 0.0295 0.0294
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0114 0.0113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.0407 0.0406
Schistosoma mansoni carbonic anhydrase-related 0.0129 0.0648 0.0647
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0151 0.015
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0159 0.0465
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0059 0.0255 0.2551
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0066 0.0296 0.0296
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0344 0.0926
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0193 0.0569
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0078 0.0078
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1802 1 1
Brugia malayi Pre-SET motif family protein 0.0066 0.0296 0.0296
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0739 0.0739
Brugia malayi Phosphoglycerate kinase 0.007 0.0322 0.0321
Schistosoma mansoni hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni opsin-like receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis carbonic anhydrase 0.0129 0.0648 0.0647
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0075 0.0075
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0238 0.1257 0.3427
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0078 0.0078
Leishmania major DNA polymerase eta, putative 0.0153 0.0781 0.2123
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0019 0.0127
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0183 0.095 0.0949
Echinococcus granulosus nuclear factor of activated T cells 5 0.0067 0.0301 0.0301
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0075 0.0075
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0019 0.0035
Echinococcus granulosus carbonic anhydrase 0.0129 0.0648 0.0647
Echinococcus multilocularis carbonic anhydrase II 0.0238 0.1257 0.1257
Entamoeba histolytica hypothetical protein 0.0037 0.0135 0.1293
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0547 0.0546
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Mycobacterium ulcerans phosphoglycerate kinase 0.0192 0.1001 0.2825
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0567 0.1536
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0027 0.0078 0.0078
Plasmodium vivax SET domain protein, putative 0.0066 0.0296 0.2954
Echinococcus granulosus dna polymerase eta 0.0153 0.0781 0.078
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0114 0.0113
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0038 0.0038
Schistosoma mansoni caspase-7 (C14 family) 0.0059 0.0255 0.0255
Onchocerca volvulus 0.0027 0.0078 0.0272
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0209
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Schistosoma mansoni ap endonuclease 0.004 0.0151 0.015
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0078 0.0078
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0019 0.0035
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0163 0.0841 0.084
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0096 0.0466 0.0466
Schistosoma mansoni amine GPCR 0.0027 0.0078 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0078 0.0078
Trypanosoma cruzi metacaspase, putative 0.0059 0.0255 0.0683
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0078 0.0078
Brugia malayi Cell death protein 3 precursor 0.0059 0.0255 0.0255
Leishmania major cysteine peptidase A (CPA) 0.0015 0.0013 0.0018
Giardia lamblia Phosphoglycerate kinase 0.0192 0.1001 1
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0064 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0046 0.0184 0.0183
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0019 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0255 0.0757
Schistosoma mansoni zinc finger protein 0.0018 0.0027 0.0026
Brugia malayi Serotonin receptor 0.0027 0.0078 0.0078
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0151 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0159 0.159
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0075 0.0075
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0078 0.0078
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0773 0.425 0.4249
Loa Loa (eye worm) pax transcription factor protein 2 0.0248 0.1312 0.1311
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0078 0.0078
Brugia malayi AKH receptor 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0044 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Brugia malayi larval opioid receptor 0.0027 0.0078 0.0078
Echinococcus granulosus histone acetyltransferase KAT2B 0.0128 0.0642 0.0642
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0739 0.0739
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0075 0.0075
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0075 0.0262
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0251 0.0672
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0151 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Echinococcus multilocularis dna polymerase kappa 0.0155 0.0795 0.0794
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0005
Leishmania major hypothetical protein, conserved 0.0018 0.0027 0.0057
Brugia malayi CHE-14 protein 0.0048 0.0193 0.0193
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0078 0.0078
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0151 0.1455
Entamoeba histolytica acetyltransferase, GNAT family 0.0035 0.0126 0.1205
Echinococcus granulosus lamin dm0 0.0024 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0183 0.095 0.0949
Echinococcus granulosus expressed conserved protein 0.0104 0.0509 0.0509
Onchocerca volvulus 0.0066 0.0296 0.1037
Leishmania major cathepsin L-like protease 0.0058 0.0251 0.0672
Trypanosoma brucei carbonic anhydrase-like protein 0.0238 0.1257 0.3427
Trypanosoma cruzi hypothetical protein 0.0066 0.0295 0.0792
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0078 0.0078
Trichomonas vaginalis set domain proteins, putative 0.0523 0.2853 0.8634
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0027 0.0078 0.0078
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.016 0.016
Onchocerca volvulus 0.0024 0.0064 0.0224
Brugia malayi Cathepsin L-like precursor 0.0015 0.0013 0.0012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0075 0.0075
Leishmania major metacaspase, putative 0.0059 0.0255 0.0683
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0019 0.0018
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0078 0.0078
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0078 0.0078
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0019 0.0035
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0078 0.0078
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0075 0.0075
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0192 0.1001 1
Brugia malayi G protein-coupled receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0193 0.0193
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0095 0.0244
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0015 0.0013 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0086 0.0407 0.0406
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0078 0.0078
Echinococcus granulosus zinc finger protein 0.0026 0.0073 0.0072
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0078 0.0272
Schistosoma mansoni opsin-like receptor 0.0027 0.0078 0.0078
Plasmodium falciparum carbonic anhydrase 0.0129 0.0648 0.6449
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0059 0.0255 0.0757
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Brugia malayi RE15519p 0.0027 0.0078 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Mycobacterium ulcerans hypothetical protein 0.0351 0.1892 0.5602
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0078 0.0078
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0075 0.0075
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.033 0.0329
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0013 0.002
Leishmania major phosphoglycerate kinase B, cytosolic 0.0192 0.1001 0.2726
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0019 0.0018
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0078 0.0078
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0078 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0251 0.0672
Brugia malayi TAR-binding protein 0.0071 0.0327 0.0327
Onchocerca volvulus 0.0015 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0075 0.0075
Trypanosoma brucei phosphoglycerate kinase 0.0192 0.1001 0.2726
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0036 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0739 0.0739
Brugia malayi hypothetical protein 0.0027 0.0078 0.0078
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0213 0.0566
Onchocerca volvulus 0.0015 0.0013 0.0042
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0066 0.0295 0.2904
Schistosoma mansoni neuropeptide receptor 0.0027 0.0078 0.0078
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0075 0.0075
Brugia malayi mbt repeat family protein 0.0161 0.0826 0.0825
Brugia malayi Papain family cysteine protease containing protein 0.0015 0.0013 0.0012
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0027 0.0078 0.0078
Brugia malayi Pre-SET motif family protein 0.046 0.2498 0.2497
Echinococcus multilocularis expressed conserved protein 0.0104 0.0509 0.0509
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0006 0.0005
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0019 0.0018
Echinococcus granulosus histone acetyltransferase MYST2 0.0183 0.095 0.0949
Schistosoma mansoni thyroid hormone receptor 0.0026 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.05 0.2721 0.2721
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0013 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0078 0.0078
Trichomonas vaginalis glutaminase, putative 0.0604 0.3303 1
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.0078
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0078 0.0078
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0795 0.2161
Loa Loa (eye worm) hypothetical protein 0.0161 0.0826 0.0825
Echinococcus granulosus tar DNA binding protein 0.0071 0.0327 0.0327
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0151 0.0397
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.0548 0.1484
Loa Loa (eye worm) hypothetical protein 0.0082 0.0386 0.0385
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0006 0.0005

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 100 uM Cytotoxicity against human HeLa cells by MTT assay ChEMBL. 19943621
IC50 (functional) > 100 uM Cytotoxicity against human SMMC7721 cells by MTT assay ChEMBL. 19943621

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.