Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0171 | 0.4063 | 0.5237 |
Schistosoma mansoni | carbonyl reductase | 0.0171 | 0.4063 | 0.7751 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0171 | 0.4063 | 0.5237 |
Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | hypothetical protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0171 | 0.4063 | 0.5 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0171 | 0.4063 | 0.5237 |
Loa Loa (eye worm) | dehydrogenase | 0.0171 | 0.4063 | 0.4063 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Loa Loa (eye worm) | integrin beta-2 | 0.0303 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Leishmania major | quinonoid dihydropteridine reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Leishmania major | short chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | quinonoid dihydropteridine reductase, putative | 0.0171 | 0.4063 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0171 | 0.4063 | 0.5 |
Plasmodium vivax | steroid dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0171 | 0.4063 | 0.5 |
Leishmania major | oxidoreductase-like protein | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | Retinol dehydrogenase 12 | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0171 | 0.4063 | 0.3122 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0171 | 0.4063 | 0.5237 |
Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0171 | 0.4063 | 0.5237 |
Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | dehydrogenases, short chain protein 2 | 0.0171 | 0.4063 | 0.3122 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0171 | 0.4063 | 0.5237 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | integrin beta subunit | 0.0178 | 0.4373 | 1 |
Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0171 | 0.4063 | 0.7751 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Leishmania major | pteridine reductase 1 | 0.0171 | 0.4063 | 0.5 |
Mycobacterium leprae | Probable oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.0228 | 0.6614 | 0.6614 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0171 | 0.4063 | 0.5237 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Giardia lamblia | Reductase, putative | 0.0171 | 0.4063 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | hypothetical protein | 0.0171 | 0.4063 | 0.3122 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.156 | 0.156 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0171 | 0.4063 | 0.5237 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0171 | 0.4063 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Plasmodium vivax | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Toxoplasma gondii | oxidoreductase, putative | 0.0171 | 0.4063 | 0.5 |
Leishmania major | short chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Leishmania major | dehydrogenase-like protein | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0171 | 0.4063 | 0.5 |
Echinococcus multilocularis | steroid dehydrogenase | 0.0171 | 0.4063 | 0.5237 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0171 | 0.4063 | 0.7751 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0171 | 0.4063 | 0.5237 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 3, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Toxoplasma gondii | carbonyl reductase 1, putative | 0.0171 | 0.4063 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Plasmodium falciparum | steroid dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.1368 | 0.1368 |
Mycobacterium ulcerans | dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase | 0.0171 | 0.4063 | 0.3122 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | integrin beta 2 | 0.0224 | 0.6452 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0171 | 0.4063 | 0.7751 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0171 | 0.4063 | 0.5237 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0171 | 0.4063 | 0.5237 |
Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0171 | 0.4063 | 0.5237 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0171 | 0.4063 | 0.5237 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium ulcerans | dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Echinococcus granulosus | retinol dehydrogenase 11 | 0.0171 | 0.4063 | 0.5237 |
Trypanosoma brucei | 3-ketoacyl-CoA reductase, putative | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | retinal dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase 2 | 0.0171 | 0.4063 | 0.5 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Toxoplasma gondii | 3-ketoacyl-CoA reductase, putative | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0171 | 0.4063 | 0.5237 |
Schistosoma mansoni | carbonyl reductase | 0.0171 | 0.4063 | 0.7751 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Onchocerca volvulus | Sepiapterin reductase homolog | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Giardia lamblia | Short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Toxoplasma gondii | oxidoreductase, putative | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4063 | 0.4063 |
Echinococcus granulosus | steroid dehydrogenase | 0.0171 | 0.4063 | 0.5237 |
Giardia lamblia | Oxidoreductase, short chain dehydrogenase/reductase family | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0171 | 0.4063 | 0.5237 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0171 | 0.4063 | 0.5237 |
Leishmania major | short chain dehydrogenase-like protein | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | oxidoreductase | 0.0171 | 0.4063 | 0.5237 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0171 | 0.4063 | 0.5 |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0171 | 0.4063 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Echinococcus multilocularis | oxidoreductase | 0.0171 | 0.4063 | 0.5237 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0171 | 0.4063 | 0.5 |
Echinococcus multilocularis | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0171 | 0.4063 | 0.5 |
Trypanosoma brucei | beta-D-hydroxybutyrate dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0171 | 0.4063 | 0.3122 |
Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Onchocerca volvulus | 0.0171 | 0.4063 | 0.5 | |
Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Echinococcus granulosus | carbonyl reductase 1 | 0.0171 | 0.4063 | 0.5237 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0171 | 0.4063 | 0.5237 |
Plasmodium falciparum | oxidoreductase, short-chain dehydrogenase family, putative | 0.0171 | 0.4063 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma brucei | 3-keto-dihydrosphingosine reductase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0171 | 0.4063 | 0.5 |
Entamoeba histolytica | short chain dehydrogenase family protein | 0.0171 | 0.4063 | 0.5 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0171 | 0.4063 | 0.5 |
Echinococcus granulosus | WW domain containing oxidoreductase | 0.0171 | 0.4063 | 0.5237 |
Echinococcus multilocularis | integrin beta 2 | 0.0224 | 0.6452 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Leishmania major | short chain dehydrogenase/reductase, putative | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | Integrin alpha pat-2 precursor | 0.0148 | 0.2996 | 0.1886 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0171 | 0.4063 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0171 | 0.4063 | 0.3122 |
Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0171 | 0.4063 | 0.5237 |
Brugia malayi | dehydrogenases, short chain protein 9 | 0.0171 | 0.4063 | 0.3122 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0171 | 0.4063 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Leishmania major | 3-keto-dihydrosphingosine reductase | 0.0171 | 0.4063 | 0.5 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0171 | 0.4063 | 0.5 |
Leishmania major | quinonoid dihydropteridine reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Schistosoma mansoni | carbonyl reductase | 0.0171 | 0.4063 | 0.7751 |
Schistosoma mansoni | steroid dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Schistosoma mansoni | short chain dehydrogenase | 0.0171 | 0.4063 | 0.7751 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0171 | 0.4063 | 0.3122 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0171 | 0.4063 | 0.5 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0171 | 0.4063 | 0.4063 |
Leishmania major | hypothetical protein, conserved | 0.0171 | 0.4063 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0171 | 0.4063 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Half-maximal inhibition of [125I]-CCK-33 binding to guinea pig brain(cortex) cholecystokinin receptor | ChEMBL. | 2885419 |
IC50 (functional) | > 100 uM | Half-maximal inhibition of binding of [125I]-gastrin to guinea pig gastric glands | ChEMBL. | 2885419 |
IC50 (binding) | ~ 150 uM | Half-maximal inhibition of [125I]-CCK-33 binding to rat pancreas cholecystokinin receptor | ChEMBL. | 2885419 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.