Detailed information for compound 1649365

Basic information

Technical information
  • TDR Targets ID: 1649365
  • Name: 1-(2-methoxyphenyl)-3-(pyridin-2-ylmethyliden eamino)thiourea
  • MW: 286.352 | Formula: C14H14N4OS
  • H donors: 2 H acceptors: 1 LogP: 2.39 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1NC(=S)N/N=C/c1ccccn1
  • InChi: 1S/C14H14N4OS/c1-19-13-8-3-2-7-12(13)17-14(20)18-16-10-11-6-4-5-9-15-11/h2-10H,1H3,(H2,17,18,20)/b16-10+
  • InChiKey: DOVQMBJFJCZODZ-MHWRWJLKSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(2-methoxyphenyl)-3-(2-pyridylmethyleneamino)thiourea
  • Neuro_000401
  • 2-Pyridinecarbaldehyde N-(2-methoxyphenyl)thiosemicarbazone
  • AIDS-161056
  • AIDS161056
  • NCI60_023790
  • NSC668298

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0032 0.0175 0.0175
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Schistosoma mansoni cpg binding protein 0.0057 0.0362 0.0362
Brugia malayi hypothetical protein 0.0031 0.0167 0.0955
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0088 0.0088
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0015 0.0049 0.0091
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0015 0.0049 0.0166
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0013 0.0032 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0088 0.0475
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0015 0.0049 0.0241
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0044 0.0264 0.0264
Schistosoma mansoni nuclear hormone receptor 0.002 0.0088 0.0088
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0442 0.1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0273 0.0273
Schistosoma mansoni protein kinase 0.0068 0.0439 0.0439
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0439 0.0439
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0049 0.004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0088 0.0088
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0362 0.2129
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0049 0.0049
Onchocerca volvulus 0.015 0.104 1
Onchocerca volvulus 0.0031 0.0167 0.1533
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0507 0.2275
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0066 0.0426 0.0417
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0083 0.0569
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0032 0.0027
Brugia malayi Calcitonin receptor-like protein seb-1 0.0202 0.1424 0.8547
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0139 0.0783
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Echinococcus multilocularis expressed protein 0.0033 0.0183 0.0173
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0088 0.0079
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0409 0.04
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0083 0.0073
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0409 0.2415
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.1 0.4553
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0013 0.0032 0.004
Trichomonas vaginalis rotamase, putative 0.0032 0.0177 0.0372
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.0247 0.5587
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0031 0.0021
Echinococcus multilocularis solute carrier family 22 0.0031 0.0167 0.0158
Giardia lamblia Lysyl-tRNA synthetase 0.0049 0.0301 0.6849
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0256 0.0537
Schistosoma mansoni DNA polymerase eta 0.0019 0.0083 0.0083
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0088 0.0079
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0202 0.1424 0.8547
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0031 0.0097
Schistosoma mansoni sugar transporter 0.0031 0.0167 0.0167
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0049 0.004
Schistosoma mansoni intermediate filament proteins 0.0027 0.0136 0.0136
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0083 0.0569
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0167 1
Schistosoma mansoni coup transcription factor 0.002 0.0088 0.0088
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0031 0.0128
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0088 0.0475
Giardia lamblia Hexose transporter 0.0031 0.0167 0.346
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Leishmania major lysyl-tRNA synthetase, putative 0.0049 0.0301 0.1329
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0442 0.1
Entamoeba histolytica protein kinase, putative 0.0068 0.0439 0.1012
Loa Loa (eye worm) hypothetical protein 0.0066 0.0426 0.2517
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0111 0.2978
Toxoplasma gondii sugar transporter ST1 0.0031 0.0167 0.0342
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0032 0.0175 0.0212
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0084 0.0554 0.0545
Onchocerca volvulus 0.0015 0.0049 0.0386
Trichomonas vaginalis dullard protein, putative 0.0013 0.0032 0.0027
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0083 0.0083
Leishmania major DNA polymerase kappa, putative 0.0019 0.0083 0.032
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0083 0.0083
Onchocerca volvulus 0.0015 0.0049 0.0386
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0621 0.0621
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0049 0.0049
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0088 0.0088
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0049 0.0297 0.0297
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Schistosoma mansoni thyroid hormone receptor 0.002 0.0088 0.0088
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0031 0.0262
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0442 0.1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0507 0.2275
Loa Loa (eye worm) histone methyltransferase 0.0018 0.007 0.0366
Giardia lamblia Sugar-proton symporter 0.0031 0.0167 0.346
Leishmania major hypothetical protein, conserved 0.0031 0.0167 0.0711
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0084 0.0554 0.0554
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Echinococcus granulosus solute carrier family 22 0.0031 0.0167 0.0158
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0442 0.1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0068 0.0439 0.2598
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0167 0.0711
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Onchocerca volvulus 0.0031 0.0167 0.1533
Onchocerca volvulus 0.0015 0.0049 0.0386
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0084 0.0554 0.0545
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0068 0.044 0.0602
Onchocerca volvulus 0.0015 0.0049 0.0386
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Loa Loa (eye worm) hypothetical protein 0.0019 0.0083 0.0442
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0357 0.2564 0.5652
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0128 0.0883 0.5278
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0442 0.1979
Loa Loa (eye worm) hypothetical protein 0.0049 0.0297 0.1739
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0167 0.0711
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0068 0.044 0.0945
Echinococcus granulosus dna polymerase kappa 0.0019 0.0083 0.0073
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0177 0.0755
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0018 0.0018
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0167 0.0158
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0068 0.044 0.0945
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.2181 1
Brugia malayi major facilitator superfamily protein 0.0031 0.0167 0.0955
Echinococcus multilocularis solute carrier family 22 0.0031 0.0167 0.0158
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0273 0.159
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.032
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0084 0.0554 0.0545
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.002 0.0031
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.1 0.4553
Trypanosoma brucei unspecified product 0.0019 0.0083 0.032
Mycobacterium ulcerans sugar transporter 0.0031 0.0167 0.134
Plasmodium falciparum mitogen-activated protein kinase 2 0.0357 0.2564 0.3727
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0044 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0167 0.0349
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Onchocerca volvulus 0.0015 0.0049 0.0386
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0273 0.0263
Schistosoma mansoni sugar transporter 0.0031 0.0167 0.0167
Trichomonas vaginalis rotamase, putative 0.0033 0.0183 0.0385
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0049 0.0297 0.0392
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0049 0.0049
Plasmodium falciparum hexose transporter 0.022 0.1562 0.2252
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0066 0.0426 1
Onchocerca volvulus 0.0027 0.0136 0.1226
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0255 0.1113
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0088 0.0475
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0088 0.0762
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Brugia malayi hypothetical protein 0.0234 0.1664 1
Toxoplasma gondii protein kinase, putative 0.0623 0.4526 1
Onchocerca volvulus 0.0031 0.0167 0.1533
Loa Loa (eye worm) hypothetical protein 0.0202 0.1424 0.8547
Loa Loa (eye worm) hypothetical protein 0.0138 0.0954 0.5708
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0167 0.0158
Schistosoma mansoni nuclear hormone receptor 0.001 0.001 0.001
Onchocerca volvulus 0.0031 0.0167 0.1533
Schistosoma mansoni sugar transporter 0.0031 0.0167 0.0167
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0088 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0013 0.0032 0.0048
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0051
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0409 0.04
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0049 0.004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0083 0.0442
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0077 0.0507 0.1093
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0031 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0088 0.0475
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0031 0.0021
Loa Loa (eye worm) hypothetical protein 0.0121 0.0832 0.4969
Loa Loa (eye worm) hypothetical protein 0.0084 0.0554 0.3291
Giardia lamblia Prolyl-tRNA synthetase 0.0066 0.0426 1
Echinococcus granulosus FTZ F1 alpha 0.002 0.0088 0.0079
Loa Loa (eye worm) hypothetical protein 0.0054 0.0335 0.1966
Onchocerca volvulus 0.0031 0.0167 0.1533
Schistosoma mansoni nuclear receptor 0.001 0.001 0.001
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0032 0.0175 0.0166
Loa Loa (eye worm) hypothetical protein 0.0013 0.0034 0.0149
Schistosoma mansoni sugar transporter 0.0031 0.0167 0.0167
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0621 0.144
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0167 0.0349
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Brugia malayi hypothetical protein 0.0031 0.0167 0.0955
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) hypothetical protein 0.0234 0.1664 1
Leishmania major ubiquitin-activating enzyme-like protein 0.0032 0.0175 0.0745
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.1664 0.1656
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0049 0.0049
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0015 0.0049 0.004
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Giardia lamblia Protein tyrosine phosphatase 0.0015 0.0049 0.0472
Loa Loa (eye worm) hypothetical protein 0.0068 0.0439 0.2598
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0507 0.2275
Echinococcus multilocularis dna polymerase eta 0.0019 0.0083 0.0073
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.002 0.0031
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0183 0.0385
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0442 0.1979
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0031 0.008
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0031 0.0167 0.134
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0256 0.0247
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0018 0.0051
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0084 0.0554 0.0554
Leishmania major DNA polymerase eta, putative 0.0019 0.0083 0.032
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0133
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Brugia malayi Cam kinase protein 1 0.0068 0.0439 0.2598
Brugia malayi Protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0136 0.0763
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0088 0.0088
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0018 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0167 0.0349
Plasmodium vivax ubiquitin activating enzyme, putative 0.0049 0.0297 0.0392
Chlamydia trachomatis lysine--tRNA ligase 0.0049 0.0301 1
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.002 0.0031
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0136 0.0763
Plasmodium falciparum calcium-dependent protein kinase 1 0.0068 0.044 0.0602
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus granulosus solute carrier family 22 0.0031 0.0167 0.0158
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0015 0.0049 0.0241
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0305 0.2181 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0066 0.0426 0.2517
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0088 0.0475
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0049 0.0297 0.0288
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.032
Onchocerca volvulus 0.0015 0.0049 0.0386
Onchocerca volvulus Huntingtin homolog 0.0121 0.0832 0.7979
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0015 0.0049 0.004
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus granulosus expressed protein 0.0033 0.0183 0.0173
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.1562 0.1553
Brugia malayi hypothetical protein 0.0015 0.0049 0.0241
Echinococcus multilocularis calcium dependent protein kinase 0.0063 0.0405 0.0396
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0357 0.2564 0.3727
Echinococcus granulosus solute carrier family 22 0.0031 0.0167 0.0158
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0301 0.2558
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0032 0.0175 0.0212
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0088 0.0079
Echinococcus multilocularis microtubule associated protein 2 0.1367 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0035 0.0036
Trypanosoma cruzi hexose transporter 0.0068 0.0442 0.1979
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0031 0.0167 0.134
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0015 0.0049 0.0049
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0031 0.1121
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0038 0.0114
Trypanosoma brucei glucose transporter 2A 0.0068 0.0442 0.1979
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0088 0.0475
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0035 0.0036
Onchocerca volvulus 0.0031 0.0167 0.1533
Schistosoma mansoni survival motor neuron protein 0.0048 0.0291 0.0291
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0256 0.0558
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Echinococcus multilocularis hypothetical protein 0.0015 0.0049 0.004
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0291 0.1702
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0049 0.0301 0.1329
Echinococcus granulosus solute carrier family 22 0.0031 0.0167 0.0158
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0442 0.1
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0167 0.0955
Onchocerca volvulus 0.0027 0.0136 0.1226
Brugia malayi nuclear receptor RXR 0.0011 0.0018 0.0051
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0031 0.0128
Schistosoma mansoni hypothetical protein 0.0168 0.1174 0.1174
Plasmodium falciparum calcium-dependent protein kinase 4 0.0068 0.044 0.0602
Echinococcus granulosus protein tyrosine phosphatase n9 0.0015 0.0049 0.004
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0409 0.04
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0439 0.043
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0066 0.0426 0.0417
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0018 0.0008
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0015 0.0051 0.0095
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0128 0.0883 0.0874
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0442 0.1979
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0049 0.0297 0.0288
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0015 0.0049 0.0166
Entamoeba histolytica hypothetical protein 0.0093 0.0621 0.144
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0177 0.0363
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0083 0.032
Loa Loa (eye worm) hypothetical protein 0.0066 0.0426 0.2517
Loa Loa (eye worm) hypothetical protein 0.0088 0.0586 0.3485
Toxoplasma gondii hypothetical protein 0.0049 0.0301 0.0637
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0035 0.0036
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trichomonas vaginalis pten, drome, putative 0.0015 0.0049 0.0069
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Brugia malayi intermediate filament protein 0.0027 0.0136 0.0763
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.002 0.0031
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0167 0.0711
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0032 0.0032
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0167 0.0711
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0229 0.5028
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0049 0.004
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0066 0.0426 0.0961
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Leishmania major glucose transporter, lmgt2 0.0068 0.0442 0.1979
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Toxoplasma gondii lysine-tRNA ligase 0.0049 0.0301 0.0638
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0049 0.004
Onchocerca volvulus 0.002 0.0088 0.0762
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0093 0.0621 0.3692
Brugia malayi hypothetical protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0032 0.0027
Onchocerca volvulus 0.0031 0.0167 0.1533
Echinococcus granulosus dna polymerase eta 0.0019 0.0083 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0088 0.0475
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0088 0.0079
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0439 0.043
Echinococcus multilocularis musashi 0.0027 0.0136 0.0126
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0015 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Onchocerca volvulus Huntingtin homolog 0.0121 0.0832 0.7979
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0013 0.0032 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0035 0.0036
Onchocerca volvulus 0.0015 0.0049 0.0386
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Onchocerca volvulus 0.0015 0.0049 0.0386
Schistosoma mansoni glucose transporter 0.0031 0.0167 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.032
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0032 0.0175 0.0745
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus granulosus cpg binding protein 0.0061 0.0386 0.0377
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.007 0.0061
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0088 0.0088
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0167 0.0349
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0167 0.0349
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Schistosoma mansoni cpg binding protein 0.0061 0.0386 0.0386
Trypanosoma brucei sugar transporter, putative 0.0031 0.0167 0.0711
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0031 0.0097
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0018 0.0008
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0585 0.4243 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0439 0.043
Onchocerca volvulus 0.0015 0.0049 0.0386
Brugia malayi hypothetical protein 0.0015 0.0049 0.0241
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0426 0.0426
Schistosoma mansoni apoptosis regulator bax 0.0084 0.0554 0.0554
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0031 0.0038
Schistosoma mansoni hypothetical protein 0.0818 0.5955 0.5955
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0177 0.0392
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.1562 0.1553
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.1 0.4553
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0088 0.0475
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0167 0.0342
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.001 0.001
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.022 0.1562 0.1553
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0255 0.1113
Giardia lamblia DINP protein human, muc B family 0.0019 0.0083 0.1315
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0049 0.004
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0031 0.0046
Plasmodium falciparum calcium-dependent protein kinase 3 0.0068 0.044 0.0602
Giardia lamblia Ubiquitin-activating enzyme E1 1 0.0015 0.0051 0.0516
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0028 0.0142 0.0593
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Onchocerca volvulus 0.0057 0.0362 0.3418
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0083 0.0442
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0031 0.0128
Schistosoma mansoni zinc finger protein 0.001 0.001 0.001
Echinococcus granulosus geminin 0.0168 0.1174 0.1165
Plasmodium falciparum protein kinase 6 0.0936 0.6827 1
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0088 0.0088
Leishmania major glucose transporter/membrane transporter D2, putative 0.0068 0.0442 0.1979
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0835 0.0835
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0167 0.0349
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0273 0.0263
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0083 0.032
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0031 0.0021
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0068 0.044 0.0602
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) hypothetical protein 0.0121 0.0832 0.4969
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0044 0.0035
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0015 0.0049 0.0241
Echinococcus granulosus lamin 0.0027 0.0136 0.0126
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0183 0.1047
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0183 0.1047
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0088 0.0475
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0015 0.0049 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0083 0.032
Onchocerca volvulus 0.0015 0.0049 0.0386
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0035 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0214 0.0927
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0031 0.0097
Onchocerca volvulus 4.1 G protein, putative homolog 0.0015 0.0049 0.0386
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0439 0.043
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.1015 0.1007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0132 0.0742
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.0126
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0013 0.0032 0.0022
Loa Loa (eye worm) hypothetical protein 0.015 0.104 0.6228
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0273 0.159
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0088 0.0079
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0229 0.0516
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0442 0.1979
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0088 0.0475
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0083 0.032
Toxoplasma gondii hypothetical protein 0.0049 0.0297 0.0629
Brugia malayi Protein kinase domain containing protein 0.0093 0.0621 0.3692
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.0257 0.0561
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0068 0.0439 0.1965
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0439 0.043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0088 0.0475
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0031 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.112 1
Schistosoma mansoni glucose transport protein 0.022 0.1562 0.1562
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0301 0.2558
Echinococcus multilocularis GPCR, family 2 0.0064 0.0409 0.04
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0202 0.1424 0.8547
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0273 0.0273
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0167 0.0955
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0128 0.0883 0.5278
Trypanosoma brucei glucose transporter 1E 0.0068 0.0442 0.1979
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0035 0.0036
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0442 0.1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0045 0.0212
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative 0.0015 0.0051 0.0073
Schistosoma mansoni nuclear receptor 0.001 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0068 0.0439 0.2598
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0088 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) sugar transporter 0.022 0.1562 0.9379
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0031 0.0128
Leishmania major glucose transporter, lmgt1 0.0068 0.0442 0.1979
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0273 0.0263
Entamoeba histolytica protein kinase, putative 0.0068 0.0439 0.1012
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0167 0.134
Brugia malayi latrophilin 2 splice variant baaae 0.0138 0.0954 0.5708
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0255 0.1113
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0256 0.0558
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0084 0.0554 0.3291
Schistosoma mansoni hypothetical protein 0.0064 0.0409 0.0409
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0088 0.0079
Loa Loa (eye worm) hypothetical protein 0.0049 0.0301 0.1764
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0015 0.0049 0.004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0088 0.0088
Echinococcus granulosus tyrosine protein kinase Lyn 0.001 0.0011 0.0002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0409 0.2415
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0088 0.0475
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0044 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0088 0.0475
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0167 0.0201
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.002 0.0031
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0167 0.0955
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0088 0.0079
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0766 0.1668
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0032 0.0032
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0305 0.2181 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0127
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0442 0.1979
Onchocerca volvulus 0.0015 0.0049 0.0386
Brugia malayi Protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0088 0.0079
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0167 0.0955
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0013 0.0032 0.0022
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0015 0.0049 0.004
Echinococcus granulosus lamin dm0 0.0027 0.0136 0.0126
Schistosoma mansoni hypothetical protein 0.0084 0.0554 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Loa Loa (eye worm) ThiF family protein 0.0032 0.0175 0.0999
Trichomonas vaginalis dullard protein, putative 0.0013 0.0032 0.0027
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0088 0.0079
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0426 0.0426
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0015 0.0049 0.0091
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0083 0.0569
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0049 0.004
Brugia malayi hypothetical protein 0.0011 0.0018 0.0051
Echinococcus multilocularis 0.0013 0.0032 0.0022
Plasmodium vivax lysine--tRNA ligase, putative 0.0049 0.0301 0.0398
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0273 0.0263
Loa Loa (eye worm) protein tyrosine phosphatase 0.0015 0.0049 0.0241
Plasmodium vivax sugar transporter, putative 0.0031 0.0167 0.0201
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0015 0.0049 0.0166
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0031 0.008
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0034 0.0025
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0083 0.0073
Brugia malayi Sugar transporter family protein 0.0031 0.0167 0.0955
Echinococcus granulosus intermediate filament protein 0.0027 0.0136 0.0126
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0128 0.0883 0.0874
Onchocerca volvulus 0.0015 0.0049 0.0386
Plasmodium falciparum lysine--tRNA ligase 0.0049 0.0301 0.0398
Leishmania major hypothetical protein, conserved 0.0011 0.002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0051
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0088 0.0762
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0051
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0324 0.1431
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0088 0.0475
Brugia malayi hypothetical protein 0.0121 0.0832 0.4969
Schistosoma mansoni hypothetical protein 0.0012 0.003 0.003
Brugia malayi lysyl-tRNA synthetase 0.0049 0.0301 0.1764
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0128 0.0883 0.0874
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0409 0.2415
Plasmodium vivax calcium-dependent protein kinase, putative 0.0068 0.044 0.0602
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0088 0.0079
Toxoplasma gondii sugar transporter ST3 0.0031 0.0167 0.0342
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0475
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0083 0.032
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0015 0.0049 0.0049
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0068 0.044 0.0602
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Brugia malayi hypothetical protein 0.0031 0.0167 0.0955
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0088 0.0475
Plasmodium vivax proline--tRNA ligase, putative 0.0077 0.0507 0.07
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Schistosoma mansoni hypothetical protein 0.0138 0.0954 0.0954
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Onchocerca volvulus 0.0015 0.0049 0.0386
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0031 0.0038
Schistosoma mansoni protein kinase 0.0068 0.0439 0.0439
Onchocerca volvulus 0.0031 0.0167 0.1533
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0088 0.0079
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0083 0.0442
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0015 0.0049 0.0241
Plasmodium vivax hexose transporter 0.022 0.1562 0.2252
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0409 0.2415
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0256 0.0537
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0255 0.1113
Echinococcus multilocularis General substrate transporter 0.0189 0.1333 0.1325
Brugia malayi ecdysteroid receptor 0.002 0.0088 0.0475
Brugia malayi hypothetical protein 0.015 0.104 0.6228
Schistosoma mansoni hypothetical protein 0.0168 0.1174 0.1174
Onchocerca volvulus 0.0015 0.0049 0.0386
Plasmodium falciparum protein kinase 7 0.0623 0.4526 0.6614
Schistosoma mansoni microtubule-associated protein tau 0.1367 1 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0127
Echinococcus granulosus calcium dependent protein kinase 0.0063 0.0405 0.0396
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0035 0.0036
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0049 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Trichomonas vaginalis dullard protein, putative 0.0013 0.0032 0.0027
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Loa Loa (eye worm) apoptosis regulator protein 0.0084 0.0554 0.3291
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0084 0.0554 0.0545
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Brugia malayi hypothetical protein 0.0015 0.0049 0.0241
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0049 0.004
Onchocerca volvulus 0.0031 0.0167 0.1533
Schistosoma mansoni lamin 0.0027 0.0136 0.0136
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.1562 0.1553
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0985 0.0977
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0031 0.008
Onchocerca volvulus 0.0015 0.0049 0.0386
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0111 1
Brugia malayi ThiF family protein 0.0049 0.0297 0.1739
Echinococcus multilocularis lamin 0.0027 0.0136 0.0126
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Schistosoma mansoni protein kinase 0.0068 0.0439 0.0439
Toxoplasma gondii facilitative glucose transporter GT1 0.022 0.1562 0.3431
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0093 0.0621 0.28
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0015 0.0049 0.004
Brugia malayi Sugar transporter family protein 0.022 0.1562 0.9379
Loa Loa (eye worm) sugar transporter 0.0031 0.0167 0.0955
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0128 0.0883 0.0883
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0068 0.0439 0.043
Leishmania major protein kinase, putative 0.0068 0.0439 0.1965
Echinococcus multilocularis geminin 0.0168 0.1174 0.1165
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0018 0.0051
Onchocerca volvulus 0.0031 0.0167 0.1533
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0068 0.0356
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0177 0.0755
Onchocerca volvulus Putative transporter 0.0031 0.0167 0.1533
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0032 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus multilocularis lysyl tRNA synthetase 0.0049 0.0301 0.0292
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0167 0.0158
Onchocerca volvulus 0.0015 0.0049 0.0386
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0066 0.0426 0.2517
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0042 0.0247 0.2062
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0035 0.0036
Schistosoma mansoni hypothetical protein 0.0048 0.0291 0.0291
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0015 0.0049 0.0049
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0015 0.0049 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0088 0.0079
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0167 0.0158
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0015 0.0049 0.004
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0011 0.002 0.0015
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0088 0.0088
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus granulosus General substrate transporter 0.0189 0.1333 0.1325
Onchocerca volvulus 0.0015 0.0049 0.0386
Echinococcus granulosus dnaJ subfamily B 0.0818 0.5955 0.5952
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0015 0.0049 0.0241
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0301 0.0301
Echinococcus multilocularis dnaJ subfamily B 0.0818 0.5955 0.5952
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0088 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0088 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Brugia malayi hypothetical protein 0.0011 0.0018 0.0051
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Schistosoma mansoni hypothetical protein 0.0064 0.0409 0.0409
Plasmodium falciparum calcium-dependent protein kinase 5 0.0068 0.044 0.0602
Trypanosoma brucei protein tyrosine phosphatase 1 0.0015 0.0049 0.0166
Onchocerca volvulus 0.0015 0.0049 0.0386
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0167 0.134
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0083 0.0148
Onchocerca volvulus 0.0031 0.0167 0.1533
Onchocerca volvulus 0.0031 0.0167 0.1533
Leishmania major hypothetical protein, conserved 0.0011 0.002 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0035 0.0036
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0439 0.043
Onchocerca volvulus 0.0048 0.0291 0.2733
Onchocerca volvulus 0.0031 0.0167 0.1533
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0167 0.0711
Loa Loa (eye worm) acetyltransferase 0.0146 0.1015 0.6078
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0083 0.0169
Echinococcus multilocularis dual specificity 0.0093 0.0621 0.0612
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0032 0.0084
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0013 0.0032 0.0027
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0015 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0088 0.0586 0.3485
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0088 0.0079
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0015 0.0049 0.0049
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.1015 0.6078
Echinococcus multilocularis solute carrier family 22 0.0031 0.0167 0.0158
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Echinococcus granulosus lysyl tRNA synthetase 0.0049 0.0301 0.0292
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0088 0.0475
Trichomonas vaginalis helicase, putative 0.0013 0.0035 0.0036
Entamoeba histolytica hypothetical protein 0.0049 0.0301 0.0686
Schistosoma mansoni cpg binding protein 0.0061 0.0386 0.0386
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.1562 0.1553
Brugia malayi steroid hormone receptor 0.002 0.0088 0.0475
Echinococcus multilocularis solute carrier family 22 0.0031 0.0167 0.0158
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.007 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0083 0.0569
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0031 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0088 0.0475
Schistosoma mansoni hypothetical protein 0.0084 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0585 0.4243 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Echinococcus multilocularis cpg binding protein 0.0061 0.0386 0.0377
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0256 0.0331
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Onchocerca volvulus 0.0031 0.0167 0.1533
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0409 0.04
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0507 0.2275
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0111 0.0829
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0031 0.0031
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Mycobacterium ulcerans hypothetical protein 0.0161 0.112 1
Echinococcus granulosus CTD small phosphatase protein like 0.0013 0.0032 0.0022
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0177 0.0755
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0015 0.0049 0.004
Trypanosoma brucei unspecified product 0.0013 0.0038 0.0114
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0083 0.0073
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0032 0.0175 0.0166
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0015 0.0049 0.0241
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.1015 0.1015
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0044 0.0035
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0088 0.0088
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0136 0.0763
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0439 0.043
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0167 0.0955
Schistosoma mansoni hypothetical protein 0.0064 0.0409 0.0409
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0083 0.032
Brugia malayi Sugar transporter family protein 0.0031 0.0167 0.0955
Brugia malayi ThiF family protein 0.0032 0.0175 0.0999
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Plasmodium falciparum proline--tRNA ligase 0.0077 0.0507 0.07
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Entamoeba histolytica protein kinase, putative 0.0093 0.0621 0.144
Echinococcus granulosus dual specificity 0.0093 0.0621 0.0612
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0507 0.2275
Brugia malayi major facilitator superfamily protein 0.0031 0.0167 0.0955
Onchocerca volvulus 0.0015 0.0049 0.0386
Onchocerca volvulus 0.0015 0.0049 0.0386
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Brugia malayi nuclear hormone receptor 0.002 0.0088 0.0475
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0015 0.0049 0.0091
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0031 0.1121
Schistosoma mansoni protein tyrosine phosphatase 0.0015 0.0049 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0439 0.0993
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.1562 0.1553
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0049 0.0301 0.6932
Echinococcus multilocularis lamin dm0 0.0027 0.0136 0.0126
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0093 0.0621 0.28
Echinococcus granulosus GPCR family 2 0.0064 0.0409 0.04
Entamoeba histolytica protein kinase, putative 0.0093 0.0621 0.144
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0044 0.0035
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0177 0.0755
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.1562 0.1553
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.001 0.001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0013 0.0032 0.0133
Plasmodium vivax CDK-related protein kinase 6, putative 0.0936 0.6827 1
Schistosoma mansoni hypothetical protein 0.0064 0.0409 0.0409
Schistosoma mansoni lamin 0.0027 0.0136 0.0136
Onchocerca volvulus 0.0015 0.0049 0.0386
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0273 0.0273
Schistosoma mansoni glucose transport protein 0.022 0.1562 0.1562
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0088 0.0762
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0083 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0136 0.0763
Leishmania major tyrosine specific protein phosphatase, putative 0.0015 0.0049 0.0166
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0031 0.0025
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0015 0.0049 0.004
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0088 0.0079
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0083 0.032
Brugia malayi hypothetical protein 0.0015 0.0049 0.0241
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0229 0.0292
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0442 0.1979
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0015 0.0049 0.0166
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0045 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0167 0.0349
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0015 0.0049 0.0049
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0015 0.0049 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Onchocerca volvulus 0.0015 0.0049 0.0386
Brugia malayi nuclear receptor NHR-88 0.002 0.0088 0.0475
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Schistosoma mansoni pcd6 interacting protein-related 0.0015 0.0049 0.0049
Trypanosoma brucei unspecified product 0.0013 0.0038 0.0114
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0049 0.0301 0.1329
Onchocerca volvulus 0.0031 0.0167 0.1533
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.1664 0.1656
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0015 0.0049 0.0241
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0068 0.0439 0.2598
Toxoplasma gondii sugar transporter ST2 0.0031 0.0167 0.0342
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0031 0.008
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0015 0.0049 0.0241
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0015 0.0049 0.004
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0015 0.0049 0.004
Leishmania major glucose transporter, lmgt3 0.0068 0.0442 0.1979
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0015 0.0049 0.004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0088 0.0475
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0066 0.0426 0.0981
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0128
Schistosoma mansoni glucose transport protein 0.022 0.1562 0.1562
Schistosoma mansoni nuclear hormone receptor 0.001 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0049 0.0241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0088 0.0475
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0167 0.134
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0442 0.1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.0247 0.2062
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0032 0.0001
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0013 0.0032 0.0084
Brugia malayi Protein-tyrosine phosphatase 1 0.0015 0.0049 0.0241
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.1562 0.1553
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0128 0.0883 0.0874
Onchocerca volvulus 0.0015 0.0049 0.0386
Plasmodium falciparum calcium-dependent protein kinase 2 0.0068 0.044 0.0602
Toxoplasma gondii ThiF family protein 0.0032 0.0175 0.0358
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0088 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.022 0.1562 0.365
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0088 0.0079
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0031 0.0021
Trypanosoma brucei glucose transporter, putative 0.0068 0.0442 0.1979
Leishmania major hypothetical protein, conserved 0.0013 0.0032 0.0084
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0167 0.0349
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0032 0.0175 0.0745
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0038 0.0114
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0015 0.0049 0.0049
Echinococcus multilocularis 0.0015 0.0049 0.004
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0093 0.0621 0.28
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0034 0.0025
Schistosoma mansoni thyroid hormone receptor 0.002 0.0088 0.0088
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0032 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0038 0.0114
Brugia malayi CXXC zinc finger family protein 0.0057 0.0362 0.2129
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0093 0.0621 0.28
Schistosoma mansoni hypothetical protein 0.022 0.1562 0.1562
Loa Loa (eye worm) hypothetical protein 0.0031 0.0167 0.0955
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0083 0.032
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0015 0.0049 0.0049
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0088 0.0475
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0015 0.0049 0.004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0088 0.0475
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0049 0.0301 0.0666
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0015 0.0049 0.004
Trypanosoma cruzi ubiquitin-activating enzyme-like protein 0.0015 0.0051 0.0174
Onchocerca volvulus 0.0031 0.0167 0.1533
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0068 0.044 0.0945
Leishmania major mitochondrial DNA polymerase beta 0.0305 0.2181 1
Schistosoma mansoni rotamase 0.0033 0.0183 0.0183

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -7.67 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.127 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.957 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.528 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.131 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.041 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.901 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.889 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -5.725 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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