Detailed information for compound 1708943

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 519.772 | Formula: C23H20BrClN2O5
  • H donors: 0 H acceptors: 3 LogP: 3.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOC(=O)[C@@H]1[C@H]2COc3c([C@@H]2N2[C@@]1(C)C(=O)N(C2=O)c1ccc(cc1)Cl)cc(cc3)Br
  • InChi: 1S/C23H20BrClN2O5/c1-3-31-20(28)18-16-11-32-17-9-4-12(24)10-15(17)19(16)27-22(30)26(21(29)23(18,27)2)14-7-5-13(25)6-8-14/h4-10,16,18-19H,3,11H2,1-2H3/t16-,18+,19+,23-/m1/s1
  • InChiKey: IKKDKEBIRMANSH-ZQDYSYBYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0054 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0039 0.0038
Schistosoma mansoni inositol monophosphatase 0.0074 0.0122 0.0433
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0122 0.0192
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0039 0.0038
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.0629 0.2318
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0025 0.0487
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0118 0.0208 0.2258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0005 0.0007
Echinococcus granulosus tar DNA binding protein 0.0076 0.0126 0.0469
Echinococcus granulosus cathepsin b 0.1391 0.2698 1
Schistosoma mansoni alpha-glucosidase 0.0149 0.0267 0.0975
Loa Loa (eye worm) hypothetical protein 0.007 0.0115 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0025 0.0025
Echinococcus granulosus bloom syndrome protein 0.0025 0.0025 0.0094
Schistosoma mansoni hypothetical protein 0.002 0.0015 0.0039
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0599 0.1149 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0039 0.0145
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0339 0.1243
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0039 0.0038
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0043 0.1033
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0095 0.0335
Brugia malayi Papain family cysteine protease containing protein 0.0466 0.0888 0.0888
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0435 0.0434
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0052 0.0462
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0178 0.0644
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0019 0.0019
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Echinococcus granulosus cathepsin L 0.0118 0.0208 0.077
Loa Loa (eye worm) hypothetical protein 0.0054 0.0082 0.0082
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Onchocerca volvulus 0.0032 0.0039 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Onchocerca volvulus 0.0241 0.0448 0.0444
Loa Loa (eye worm) hypothetical protein 0.1391 0.2698 0.2698
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0039 0.0145
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0048 0.0161
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0185 0.0339 0.2425
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0027 0.0215
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Onchocerca volvulus Cathepsin L homolog 0.0118 0.0208 0.0203
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0006 0.0023
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0043 0.0042
Loa Loa (eye worm) RecQ helicase 0.0025 0.0025 0.0025
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0039 0.0039
Brugia malayi Inositol-1 0.0074 0.0122 0.0121
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0028 0.0045
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0006 0.0005
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0599 0.1149 1
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0039 0.0127
Onchocerca volvulus 0.0466 0.0888 0.0884
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0118 0.0208 0.1938
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0014 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0466 0.0888 0.8371
Mycobacterium ulcerans hypothetical protein 0.0112 0.0195 0.5625
Brugia malayi hypothetical protein 0.0126 0.0223 0.0222
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0052 0.0502
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0054 1
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0005 0.0008
Brugia malayi glutathione reductase 0.0048 0.0071 0.007
Toxoplasma gondii melibiase subfamily protein 0.0106 0.0184 0.1826
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0034 0.0033
Entamoeba histolytica G protein alpha subunit, putative 0.0014 0.0005 0.0018
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0019 0.007
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0039 0.0034
Plasmodium falciparum serine repeat antigen 4 0.0118 0.0208 0.2258
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0005 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0325 0.0613 0.5763
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0039 0.0039
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0014 0.0005 0.0019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0039 0.0038
Onchocerca volvulus 0.0466 0.0888 0.0884
Echinococcus multilocularis musashi 0.0055 0.0084 0.0132
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0035
Plasmodium falciparum serine repeat antigen 9 0.0118 0.0208 0.2258
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0005 0.0004
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0014 0.0005 0.0004
Onchocerca volvulus Glucosylceramidase homolog 0.0364 0.0688 0.0684
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Brugia malayi hypothetical protein 0.0021 0.0019 0.0018
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0005 0.002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0115 0.0408
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0095 0.0916
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.0195 0.0195
Onchocerca volvulus 0.0021 0.0019 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Echinococcus multilocularis cysteine protease 0.0466 0.0888 0.1404
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0118 0.0208 0.0207
Onchocerca volvulus 0.0055 0.0084 0.0079
Loa Loa (eye worm) beta-lactamase 0.0112 0.0195 0.0195
Giardia lamblia Cathepsin L-like protease 0.0118 0.0208 0.205
Schistosoma mansoni alpha-glucosidase 0.0149 0.0267 0.0975
Schistosoma mansoni cathepsin F (C01 family) 0.0466 0.0888 0.3281
Leishmania major pyruvate kinase 0.0034 0.0043 0.0412
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0015 0.0056
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.001 0.0009
Brugia malayi Importin beta-1 subunit 0.0035 0.0045 0.0044
Toxoplasma gondii cathepsin CPL 0.0466 0.0888 0.9079
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0039 0.0038
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0466 0.0888 1
Schistosoma mansoni hypothetical protein 0.006 0.0095 0.0335
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.001 0.0009
Echinococcus granulosus GPCR family 2 0.0017 0.0011 0.004
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0178 0.0651
Brugia malayi Thioredoxin reductase 0.0048 0.0071 0.007
Schistosoma mansoni pyruvate kinase 0.0034 0.0043 0.0142
Loa Loa (eye worm) hypothetical protein 0.0325 0.0613 0.0613
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0067
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0121
Giardia lamblia Cathepsin L-like protease 0.0118 0.0208 0.205
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.0178 0.0661
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Leishmania major hypothetical protein, conserved 0.0052 0.0079 0.0782
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0045 0.04
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0124 0.0442
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0038 0.0121
Brugia malayi PHD-finger family protein 0.0022 0.0019 0.0019
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0124 0.0442
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0023 0.0084
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0122 0.3399
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0466 0.0888 0.0888
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.001 0.0015
Plasmodium falciparum cysteine proteinase falcipain 3 0.0466 0.0888 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0039 0.0038
Loa Loa (eye worm) inositol-1 0.0074 0.0122 0.0122
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0208 0.0208
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0025 0.0214
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0006 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0039 0.0127
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0052 0.0182
Brugia malayi nuclear receptor NHR-88 0.0015 0.0006 0.0005
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1391 0.2698 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0051 0.0431
Plasmodium falciparum serine repeat antigen 8 0.0118 0.0208 0.2258
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0039 0.0127
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Echinococcus granulosus cpg binding protein 0.0037 0.0049 0.018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0039 0.0062
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0208 0.2258
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Plasmodium falciparum serine repeat antigen 5 0.0118 0.0208 0.2258
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0095
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0118 0.0208 0.2258
Schistosoma mansoni ran 0.0026 0.0027 0.0082
Trypanosoma brucei glucosidase, putative 0.0038 0.0052 0.0525
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0006 0.0005
Schistosoma mansoni rab6-interacting 0.0021 0.0019 0.0051
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.001 0.0018
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0118 0.0208 0.2258
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0142 0.0141
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0052 0.0462
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0039 0.0127
Brugia malayi steroid hormone receptor 0.0032 0.0039 0.0038
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.0195 0.5625
Brugia malayi RNA binding protein 0.0076 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Schistosoma mansoni intermediate filament proteins 0.0055 0.0084 0.0292
Loa Loa (eye worm) fibroinase 0.0466 0.0888 0.0888
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0039 0.0038
Onchocerca volvulus 0.0031 0.0038 0.0033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0015 0.0056
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0079 0.0283
Schistosoma mansoni pyruvate kinase 0.0017 0.0011 0.0022
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0011 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0017
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0005 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Schistosoma mansoni lipoxygenase 0.0128 0.0227 0.0823
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.0629 0.2332
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.0195 0.1364
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0208 0.1938
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0015 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.0629 0.2318
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0005 0.0008
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0005 0.0004
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0023 0.0209
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.0484 0.4546
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0043 0.0042
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0028 0.0105
Schistosoma mansoni cpg binding protein 0.0035 0.0045 0.0148
Plasmodium vivax hypothetical protein, conserved 0.006 0.0095 0.0975
Echinococcus multilocularis lamin dm0 0.0055 0.0084 0.0132
Brugia malayi cathepsin B-like cysteine proteinase 0.1391 0.2698 0.2697
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0014 0.0005 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0195 0.1817
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0215 0.1508
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0943 0.3496
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0051 0.0456
Plasmodium vivax unspecified product 0.0259 0.0484 0.5397
Loa Loa (eye worm) ctsf protein 0.0466 0.0888 0.0888
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Echinococcus granulosus cysteine protease 0.0259 0.0484 0.1793
Schistosoma mansoni cathepsin S (C01 family) 0.0118 0.0208 0.0754
Entamoeba histolytica Ran family GTPase 0.0026 0.0027 0.0211
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0208 0.0754
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0051 0.0421
Echinococcus multilocularis cpg binding protein 0.0037 0.0049 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Schistosoma mansoni polycystin 1-related 0.0021 0.0019 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0051 0.0494
Onchocerca volvulus 0.0021 0.0019 0.0014
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0039 0.0127
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Mycobacterium ulcerans beta-lactamase 0.0112 0.0195 0.5625
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0325 0.0613 0.0613
Echinococcus granulosus RUN 0.0021 0.0019 0.0069
Onchocerca volvulus 0.0466 0.0888 0.0884
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0015 0.0038
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0052 0.0462
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0019 0.0105
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0023 0.4123
Giardia lamblia Cathepsin B precursor 0.0512 0.0978 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0015
Entamoeba histolytica hypothetical protein 0.0028 0.0032 0.0255
Brugia malayi isocitrate dehydrogenase 0.0017 0.001 0.0009
Brugia malayi hypothetical protein 0.0014 0.0005 0.0004
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0025 0.004
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Onchocerca volvulus Cathepsin L homolog 0.0466 0.0888 0.0884
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.0195 0.1364
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0043 0.0149
Schistosoma mansoni hypothetical protein 0.0023 0.0023 0.0066
Echinococcus multilocularis cysteine protease 0.0466 0.0888 0.1404
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0005 0.0007
Brugia malayi Pre-SET motif family protein 0.0212 0.0391 0.039
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0045
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.001 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0208 0.1938
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0208 0.205
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Loa Loa (eye worm) RNA binding protein 0.0076 0.0126 0.0126
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0045 0.0456
Echinococcus granulosus expressed protein 0.0014 0.0005 0.0018
Brugia malayi nuclear receptor RXR 0.0017 0.001 0.0009
Mycobacterium ulcerans lipase LipD 0.0112 0.0195 0.5625
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0019
Toxoplasma gondii cathepsin CPC1 0.0118 0.0208 0.2076
Leishmania major cysteine peptidase A (CPA) 0.0466 0.0888 0.9082
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0025 0.0487
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0118 0.0208 0.1938
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Schistosoma mansoni ap endonuclease 0.0039 0.0054 0.0182
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0051 0.0189
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0208 0.0207
Echinococcus multilocularis pyruvate kinase 0.0027 0.0029 0.0046
Echinococcus multilocularis cathepsin L cysteine protease 0.0466 0.0888 0.1404
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2698 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0185 0.0339 0.1258
Trichomonas vaginalis glucosylceramidase, putative 0.0383 0.0726 0.6839
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0039 0.0062
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0019 0.0029
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0118 0.0208 0.2258
Entamoeba histolytica hypothetical protein 0.0118 0.0208 0.1789
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0071 0.045
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0019
Brugia malayi Bromodomain containing protein 0.006 0.0095 0.0094
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0039 0.0127
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0043 0.0436
Plasmodium vivax vivapain-1 0.0259 0.0484 0.5397
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Onchocerca volvulus 0.0325 0.0613 0.0608
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0208 0.1789
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0054 0.0446
Brugia malayi Pre-SET motif family protein 0.0031 0.0038 0.0037
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.004
Brugia malayi Isocitrate dehydrogenase 0.0017 0.001 0.0009
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0054 0.02
Loa Loa (eye worm) hypothetical protein 0.0141 0.0253 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0314 0.1165
Schistosoma mansoni importin beta-1 0.0035 0.0045 0.0149
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0023 0.1237
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0015 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.0195 0.1364
Loa Loa (eye worm) hypothetical protein 0.0147 0.0265 0.0265
Echinococcus granulosus pyruvate kinase 0.0034 0.0043 0.0159
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.0629 0.2318
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0039 0.0038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2698 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0208 0.0754
Schistosoma mansoni ap endonuclease 0.0039 0.0054 0.0182
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0052 0.0192
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0208 0.0208
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0039 0.0127
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.0484 0.0483
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0208 0.0761
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0015 0.0154
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0182
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0027
Schistosoma mansoni protein phosphatase 2C 0.002 0.0015 0.0038
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0014 0.0005 0.0005
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.0195 0.1364
Trichomonas vaginalis set domain proteins, putative 0.0241 0.0448 0.4209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0009 0.0067
Plasmodium falciparum serine repeat antigen 3 0.0118 0.0208 0.2258
Brugia malayi Cathepsin L-like precursor 0.0141 0.0253 0.0252
Brugia malayi hypothetical protein 0.0034 0.0043 0.0042
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0048 0.0076
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0126 0.0126
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0006 0.0006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0215 1
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0006 0.0005
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0006 0.0023
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0039 0.0145
Loa Loa (eye worm) hypothetical protein 0.0055 0.0084 0.0084
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0015 0.0038
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Schistosoma mansoni hypothetical protein 0.0037 0.005 0.0168
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Trypanosoma cruzi cysteine proteinase, putative 0.0259 0.0484 0.1785
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0084 0.0083
Schistosoma mansoni jumonji domain containing protein 0.0157 0.0284 0.1038
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.1217
Brugia malayi cathepsin L-like cysteine proteinase 0.0118 0.0208 0.0207
Onchocerca volvulus 0.5124 1 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0054 0.0508
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0006 0.0023
Entamoeba histolytica hypothetical protein 0.0024 0.0023 0.0178
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0333 0.0629 0.0628
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0051 0.0456
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0142 0.0224
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0051 0.0081
Onchocerca volvulus Cathepsin L homolog 0.0466 0.0888 0.0884
Brugia malayi hypothetical protein 0.0017 0.001 0.0009
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0032 0.0109
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0554 0.1061 0.106
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0079 0.0283
Leishmania major importin beta-1 subunit, putative 0.0028 0.0032 0.03
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0084 0.0142 0.0142
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Schistosoma mansoni ran 0.0026 0.0027 0.0082
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0015 0.0092
Brugia malayi nuclear receptor NHR-67 0.0015 0.0006 0.0005
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.124
Leishmania major hypothetical protein, conserved 0.0216 0.0399 0.406
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0084 0.0083
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0038 0.0059
Onchocerca volvulus 0.0466 0.0888 0.0884
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0043 0.0038
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0051 0.0518
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0039 0.0034
Entamoeba histolytica cysteine proteinase 2 0.0259 0.0484 0.4197
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0943 0.149
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0082 0.0745
Loa Loa (eye worm) hypothetical protein 0.0125 0.0222 0.0222
Brugia malayi jmjC domain containing protein 0.0198 0.0364 0.0363
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.005 0.0049
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0005 0.0004
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0019 0.0069
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.0441
Onchocerca volvulus 0.0112 0.0195 0.019
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0006 0.0005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0071 0.0112
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.005
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0009 0.0009
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0006 0.0023
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0054 0.0461
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0039 0.0039
Giardia lamblia Cathepsin B precursor 0.0512 0.0978 1
Plasmodium vivax glutathione reductase, putative 0.0048 0.0071 0.0697
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0006 0.0005
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0043 0.0038
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Trichomonas vaginalis esterase, putative 0.0112 0.0195 0.1817
Schistosoma mansoni rab6-interacting 0.0021 0.0019 0.0051
Giardia lamblia Hypothetical protein 0.0118 0.0208 0.205
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0084 0.0084
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.047
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0006 0.001
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0006 0.0005
Echinococcus granulosus lamin dm0 0.0055 0.0084 0.031
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0039 0.0062
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.001 0.0002
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0014 0.0005 0.0019
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0466 0.0888 0.0888
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0043 0.0149
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0025 0.004
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0051 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Brugia malayi cathepsin F-like cysteine proteinase 0.0141 0.0253 0.0252
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0208 0.0207
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0009 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0195 0.0713
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Plasmodium falciparum serine repeat antigen 6 0.0118 0.0208 0.2258
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0005 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0048 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0039 0.0038
Trypanosoma cruzi cysteine peptidase, putative 0.0141 0.0253 0.0927
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0195 0.2112
Echinococcus multilocularis pyruvate kinase 0.0034 0.0043 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0039 0.0039
Entamoeba histolytica cysteine proteinase 1, putative 0.0259 0.0484 0.4197
Trypanosoma cruzi cysteine proteinase, putative 0.0259 0.0484 0.1785
Onchocerca volvulus 0.0015 0.0006 0.0001
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0005 0.0018
Schistosoma mansoni cathepsin B (C01 family) 0.0118 0.0208 0.0754
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0039 0.0038
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0484 0.1778
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0023
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0115 0.0408
Schistosoma mansoni cathepsin C 0.0118 0.0208 0.0754
Loa Loa (eye worm) hypothetical protein 0.0104 0.018 0.018
Toxoplasma gondii aldehyde dehydrogenase 0.0185 0.0339 0.343
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0043 0.0436
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0054 0.1351
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0039 0.0038
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0027 0.0043
Echinococcus granulosus cathepsin b 0.1391 0.2698 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0019 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0215 0.1508
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0006 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0216 0.0399 0.4075
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Echinococcus granulosus phd:f box containing protein 0.002 0.0015 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0106 0.4345
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0118 0.0208 0.1938
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Onchocerca volvulus 0.0055 0.0084 0.0079
Plasmodium falciparum importin beta, putative 0.0035 0.0045 0.0405
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0079 0.0793
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0118 0.0208 0.2258
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0095 0.015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0005 0.0018
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0095 0.0352
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0054 0.0054
Plasmodium falciparum serine repeat antigen 2 0.0118 0.0208 0.2258
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0006 0.0023
Mycobacterium tuberculosis Conserved protein 0.0112 0.0195 0.1364
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0038
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Brugia malayi hypothetical protein 0.0017 0.001 0.0009
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0554 0.1061 0.1061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0014 0.0005 0.0005
Brugia malayi G-protein alpha subunit 0.0014 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0082 0.0745
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0215 0.1508
Brugia malayi jmjC domain containing protein 0.0075 0.0124 0.0123
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0208 0.0207
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0191 0.1332
Brugia malayi hypothetical protein 0.0021 0.0019 0.0018
Leishmania major pyruvate kinase 0.0034 0.0043 0.0412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0039 0.0127
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0208 0.205
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0003 0.0025
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0071 0.0697
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0208 0.1938
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0079 0.0793
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0208 0.0761
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0118 0.0208 0.205
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0014 0.0005 0.0019
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.0195 0.1991
Brugia malayi hypothetical protein 0.0052 0.0079 0.0078
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0015 0.0024
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Brugia malayi hypothetical protein 0.0147 0.0265 0.0264
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0051 0.0172
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0106 0.0184 0.029
Brugia malayi hypothetical protein 0.0015 0.0006 0.0005
Loa Loa (eye worm) DR-78 0.0015 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0208 0.2258
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0118 0.0208 0.0754
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0005 0.0045
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0054 0.0548
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0051
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0039 0.0062
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Brugia malayi Cathepsin L-like precursor 0.0325 0.0613 0.0612
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0208 0.1789
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0079 0.0751
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0128 0.0227 0.0358
Brugia malayi intermediate filament protein 0.0055 0.0084 0.0083
Schistosoma mansoni zinc finger protein 0.0015 0.0006 0.0005
Schistosoma mansoni pyruvate kinase 0.0034 0.0043 0.0142
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0017
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0014 0.0005 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0045 0.0045
Onchocerca volvulus 0.0035 0.0045 0.004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0039 0.0038
Echinococcus multilocularis GPCR, family 2 0.0017 0.0011 0.0017
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0259 0.0259
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0122 0.0451
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0339 1
Trypanosoma cruzi cysteine peptidase, putative 0.0259 0.0484 0.1785
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0052 0.0182
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0054 0.0328
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.001 0.0025
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0039 0.0145
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0011 0.004
Plasmodium falciparum serine repeat antigen 1 0.0118 0.0208 0.2258
Schistosoma mansoni nuclear receptor 0.0015 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.0372 0.0704 0.2596
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0095 0.0916
Schistosoma mansoni kinase 0.0055 0.0084 0.0295
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.0484 0.4546
Schistosoma mansoni jumonji domain containing protein 0.002 0.0015 0.0038
Echinococcus granulosus cathepsin L cysteine protease 0.0259 0.0484 0.1793
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0051 0.0456
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0118 0.0208 0.2258
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0051 0.0189
Schistosoma mansoni lamin 0.0055 0.0084 0.0292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0325 0.0613 0.5763
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0011 0.0048
Echinococcus granulosus cathepsin l1 0.0466 0.0888 0.3293
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0039 0.0039
Echinococcus multilocularis lamin 0.0055 0.0084 0.0132
Echinococcus granulosus intermediate filament protein 0.0055 0.0084 0.031
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0191 0.8753
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0191 0.1332
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0009 0.0062
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0011 0.001
Onchocerca volvulus 0.0015 0.0006 0.0001
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0122 0.1122
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0039 0.0127
Echinococcus granulosus cathepsin L cysteine proteinase 0.0466 0.0888 0.3293
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.0427
Brugia malayi tailless protein 0.0015 0.0006 0.0005
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0118 0.0208 0.2258
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0314 0.0497
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0005 0.0017
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Plasmodium vivax unspecified product 0.0118 0.0208 0.2258
Schistosoma mansoni alpha glucosidase 0.0038 0.0052 0.0174
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0039 0.0127
Toxoplasma gondii exonuclease III APE 0.0039 0.0054 0.0492
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0045 0.0456
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0124 0.0124
Trichomonas vaginalis glucosylceramidase, putative 0.0383 0.0726 0.6839
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0325 0.0613 0.2262
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0023 0.0158
Echinococcus multilocularis RUN 0.0021 0.0019 0.0029
Echinococcus multilocularis cathepsin L 0.0259 0.0484 0.0764
Plasmodium vivax hypothetical protein, conserved 0.0022 0.002 0.0117
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.0441
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Schistosoma mansoni inositol monophosphatase 0.0074 0.0122 0.0433
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2698 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.0195 0.0308
Mycobacterium leprae Probable lipase LipE 0.0112 0.0195 0.8976
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0512 0.0978 0.9217
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Brugia malayi fibroinase precursor 0.0118 0.0208 0.0207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0259 0.0484 0.4945
Schistosoma mansoni nuclear receptor 0.0015 0.0006 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0466 0.0888 0.7728
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Plasmodium falciparum cysteine proteinase falcipain 1 0.0259 0.0484 0.5397
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0023 0.0176
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0201
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0121
Plasmodium vivax vivapain-3 0.0259 0.0484 0.5397
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.001 0.0015
Schistosoma mansoni cpg binding protein 0.0037 0.0049 0.0162
Mycobacterium tuberculosis Conserved protein 0.0025 0.0025 0.0118
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0025 0.0214
Echinococcus multilocularis cathepsin L 0.0118 0.0208 0.0328
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Plasmodium vivax SET domain protein, putative 0.0031 0.0038 0.0321
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0023 0.0158
Plasmodium vivax vivapain-2 0.0466 0.0888 1
Plasmodium falciparum glutathione reductase 0.0048 0.0071 0.0697
Entamoeba histolytica cysteine protease, putative 0.0466 0.0888 0.7728
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0126 0.02
Brugia malayi conserved hypotetical protein 0.0015 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0142 0.0508
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0195 0.1817
Brugia malayi Doublecortin family protein 0.0021 0.0019 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0195 0.1817
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0009 0.0062
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0054 0.3976
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Echinococcus granulosus cathepsin l cysteine peptidase 0.0466 0.0888 0.3293
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0118 0.0208 0.0754
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0051 0.0081
Brugia malayi Melibiase family protein 0.007 0.0115 0.0114
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.001 0.0036
Brugia malayi nuclear receptor RXR 0.0015 0.0006 0.0005
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0015 0.0056
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0259 0.0259
Brugia malayi hypothetical protein 0.0015 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0178 0.0651
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0208 0.2258
Toxoplasma gondii cathepsin B 0.0512 0.0978 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0092
Mycobacterium ulcerans hypothetical protein 0.0025 0.0025 0.0487
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0484 0.1778
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0032 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0399 0.1469
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0039 0.0145
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0014 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0118 0.0208 0.1938
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0339 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0009 0.0033
Echinococcus multilocularis pyruvate kinase 0.0034 0.0043 0.0068
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0015 0.0024
Plasmodium falciparum serine repeat antigen 7 0.0118 0.0208 0.2258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0259 0.0484 0.4945
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0006 0.0001
Brugia malayi ecdysone receptor 0.0015 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.001 0.0025
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0006 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Loa Loa (eye worm) glutathione reductase 0.0048 0.0071 0.0071
Echinococcus multilocularis expressed protein 0.0014 0.0005 0.0008
Onchocerca volvulus 0.0084 0.0142 0.0137
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0009 0.0033
Giardia lamblia Hypothetical protein 0.0118 0.0208 0.205
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0015 0.0024
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0005 0.0018
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0019 0.0069
Echinococcus multilocularis phd:f box containing protein 0.002 0.0015 0.0024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0011
Giardia lamblia Pyruvate kinase 0.0017 0.0011 0.0015
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0484 0.1778
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0208 0.0207
Mycobacterium tuberculosis Conserved protein 0.0112 0.0195 0.1364
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0014 0.0005 0.0019
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0043 0.0043
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0141 0.0253 0.0252
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0122 0.1122
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.001 0.0069
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0122 0.1122
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0015 0.0015
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0195 0.0713
Toxoplasma gondii preprocathepsin c precursor, putative 0.0118 0.0208 0.2076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0704 0.0704
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.0195 0.0723
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0195 0.1817
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0015 0.0097
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0015
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.012 0.019
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0011 0.004
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0027 0.009
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0126 0.0126
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0466 0.0888 0.1404
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0039 0.0038
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0009 0.0092
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.001 0.0094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0006 0.001
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.001 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.0484 0.0483
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0009 0.0024
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Schistosoma mansoni cathepsin F (C01 family) 0.0466 0.0888 0.3281
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0039 0.0127
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0006 0.001
Echinococcus multilocularis cathepsin b 0.1391 0.2698 0.4263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Brugia malayi beta-lactamase 0.0112 0.0195 0.0194
Giardia lamblia Pyruvate kinase 0.0034 0.0043 0.0348
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0036 0.0048 0.0161
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0025 0.0232
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0118 0.0208 0.2258
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.0195 0.1364
Leishmania major hypothetical protein, conserved 0.0112 0.0195 0.1971
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0051 0.0081
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0071 0.0252
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0118 0.0208 0.0208
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0006 0.001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0039 0.0062
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0015 0.0045
Onchocerca volvulus Alhambra homolog 0.006 0.0095 0.009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0039 0.0038
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0019 0.003
Toxoplasma gondii ABC1 family protein 0.0112 0.0195 0.1944
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0025 0.0084
Entamoeba histolytica cysteine proteinase, putative 0.0466 0.0888 0.7728
Echinococcus multilocularis cathepsin L cysteine protease 0.0466 0.0888 0.1404
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0713 0.1371 1
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0191 0.1332
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0015 0.0015
Trichomonas vaginalis ran, putative 0.0026 0.0027 0.0228
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0011 0.0017
Echinococcus granulosus snurportin 1 0.0372 0.0704 0.261
Plasmodium vivax unspecified product 0.0141 0.0253 0.2769
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0014 0.0005 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0014 0.0005 0.0018
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0106 0.0184 0.029
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0039 0.0039
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.0195 0.1364
Schistosoma mansoni cathepsin s 0.0141 0.0253 0.0921
Echinococcus granulosus lamin 0.0055 0.0084 0.031
Schistosoma mansoni hypothetical protein 0.0494 0.0943 0.3484
Loa Loa (eye worm) jmjC domain-containing protein 0.0125 0.0221 0.0221
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Brugia malayi Cathepsin L-like precursor 0.0325 0.0613 0.0612
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.007 0.0115 0.1057
Echinococcus granulosus pyruvate kinase 0.0034 0.0043 0.0159
Trypanosoma brucei cysteine peptidase C (CPC) 0.0512 0.0978 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.001 0.0036
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.0178 0.1531
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.0195 0.0194
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0314 0.0497
Schistosoma mansoni hypothetical protein 0.0021 0.0019 0.0051
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0027 0.0272
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Brugia malayi cathepsin L-like precursor 0.0325 0.0613 0.0612
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0009 0.0024
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0014 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0028
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0052 0.0051
Leishmania major GTP-binding protein, putative 0.0026 0.0027 0.0248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Brugia malayi nuclear hormone receptor 0.0032 0.0039 0.0038
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0054 0.0508
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0005 0.0008
Schistosoma mansoni phd/f-box containing protein 0.002 0.0015 0.0038
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.0178 0.0178
Schistosoma mansoni lipoxygenase 0.0089 0.0151 0.0544
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0054 0.0483
Trypanosoma cruzi cruzipain precursor, putative 0.0141 0.0253 0.0927
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0039 0.0062
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0512 0.0978 0.3613
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0043 0.0038
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0025 0.0487
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0032 0.0276
Brugia malayi beta-lactamase family protein 0.0112 0.0195 0.0194
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0051 0.0179
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0038 0.0059
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0023 0.042
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Brugia malayi Cathepsin L-like cysteine proteinase 0.0325 0.0613 0.0612
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0054 0.0524
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.001 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Brugia malayi beta-lactamase family protein 0.0112 0.0195 0.0194
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1391 0.2698 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0185 0.0339 0.3452
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0314 0.0314
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Trypanosoma cruzi cruzipain precursor, putative 0.0466 0.0888 0.3286
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0043 0.038
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0054 0.0085
Onchocerca volvulus 0.0112 0.0195 0.019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0084 0.0084
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0512 0.0978 0.3618
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0051 0.005
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0084 0.0083
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0195 0.0706
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0208 0.0207
Plasmodium vivax vivapain-2 0.0466 0.0888 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0054 0.019
Loa Loa (eye worm) hypothetical protein 0.0141 0.0253 0.0253
Leishmania major hypothetical protein, conserved 0.002 0.0015 0.0125
Echinococcus granulosus peregrin 0.006 0.0095 0.0352
Trypanosoma brucei polo-like protein kinase 0.0103 0.0178 0.182
Loa Loa (eye worm) hypothetical protein 0.0325 0.0613 0.0613
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0015 0.015
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0025 0.0084
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.001 0.0018
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0185 0.0339 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0208 0.1938
Trypanosoma cruzi cysteine protease, putative 0.0259 0.0484 0.1785
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0017
Brugia malayi cathepsin L precursor 0.0118 0.0208 0.0207
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0122 0.1188
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.002 0.0117
Brugia malayi cathepsin F-like cysteine proteinase 0.0118 0.0208 0.0207
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0015 0.0154
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0141 0.0524
Loa Loa (eye worm) hypothetical protein 0.0466 0.0888 0.0888
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0333 0.0629 0.0629
Echinococcus multilocularis peregrin 0.006 0.0095 0.015
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0122 0.1036
Loa Loa (eye worm) cathepsin B 0.0512 0.0978 0.0978
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0039 0.0038
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0034 0.0034
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.0178 0.0282
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0023 0.0036
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0314 0.0314
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.002 0.0117
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0023 0.0102
Plasmodium vivax importin-beta 2, putative 0.0035 0.0045 0.0405
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.0427
Leishmania major trypanothione reductase 0.0048 0.0071 0.0695
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0208 0.205
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.0391 0.0391
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Schistosoma mansoni loxhd1 0.0021 0.0019 0.0051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0015 0.0045
Loa Loa (eye worm) IKK protein kinase 0.5124 1 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0043 0.0247
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Loa Loa (eye worm) hypothetical protein 0.0141 0.0253 0.0253
Onchocerca volvulus 0.0147 0.0265 0.026
Mycobacterium tuberculosis Conserved protein 0.0112 0.0195 0.1364
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0124 0.0459
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0071 0.0071
Echinococcus granulosus importin subunit beta 1 0.0035 0.0045 0.0167
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0014 0.0005 0.0008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0052 0.0462
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0005 0.0018
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0015 0.0092
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0198 0.0364 0.1349
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0015 0.0039
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0038 0.0038
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0512 0.0978 1
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0014 0.0005 0.0004
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Toxoplasma gondii cathepsin CPC2 0.0118 0.0208 0.2076
Giardia lamblia Encystation-specific protease 0.0118 0.0208 0.205
Onchocerca volvulus Huntingtin homolog 0.0126 0.0223 0.0218
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0095 0.0095
Schistosoma mansoni coup transcription factor 0.0032 0.0039 0.0127
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0118 0.0208 0.2258
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0092
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.0195 0.1364
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0039 0.0062
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0084 0.0084
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0019 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0043 0.038
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0025 0.0094
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0128 0.0227 0.084
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0009 0.0092
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0198 0.0364 0.0575
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Schistosoma mansoni cathepsin F (C01 family) 0.0325 0.0613 0.2257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0027 0.009
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0011 0.001
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.0178 0.0174
Giardia lamblia Cathepsin B precursor 0.0512 0.0978 1
Echinococcus multilocularis cathepsin b 0.1391 0.2698 0.4263
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0195 0.1817
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0399 0.1469
Onchocerca volvulus 0.0466 0.0888 0.0884
Onchocerca volvulus 0.0466 0.0888 0.0884
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0045 0.0071
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0126 0.0223 0.0223
Plasmodium falciparum pyruvate kinase 0.0034 0.0043 0.0383
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.001 0.001
Onchocerca volvulus 0.0112 0.0195 0.019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0123 0.0438
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0122 1
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0043 0.0383
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0015 0.0064
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0054 0.019
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0108 0.1044
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0023 0.3111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.0629 0.0994
Loa Loa (eye worm) G protein alpha subunit 3 0.0014 0.0005 0.0005
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0039 0.0034
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0019 0.0105
Chlamydia trachomatis pyruvate kinase 0.0034 0.0043 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0039 0.0062
Mycobacterium ulcerans hypothetical protein 0.0025 0.0025 0.0487
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0023 0.0023
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0009 0.0067
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Onchocerca volvulus Huntingtin homolog 0.0126 0.0223 0.0218
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0208 0.2258
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0141 0.0253 0.0253
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0006 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0106 0.0184 0.068
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Schistosoma mansoni cpg binding protein 0.0037 0.0049 0.0162
Echinococcus granulosus cathepsin l1 0.0325 0.0613 0.227
Brugia malayi PHD-finger family protein 0.006 0.0095 0.0094
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.0629 0.2332
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.0195 0.5625
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0126 0.0223 0.0223
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Mycobacterium leprae conserved hypothetical protein 0.0112 0.0195 0.8976
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0141 0.0223
Giardia lamblia Kinase, PLK 0.0103 0.0178 0.1745
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0026
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0043 0.038
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.0178 0.18
Onchocerca volvulus Cathepsin F homolog 0.0466 0.0888 0.0884
Echinococcus multilocularis snurportin 1 0.0372 0.0704 0.1112
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0006 0.0005
Brugia malayi nuclear receptor NHR-88 0.0032 0.0039 0.0038
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0079 0.0793
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0466 0.0888 1
Loa Loa (eye worm) cysteine protease 0.0466 0.0888 0.0888
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0191 0.1332
Onchocerca volvulus 0.0466 0.0888 0.0884
Brugia malayi MH2 domain containing protein 0.0144 0.0259 0.0258
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0039 0.0062
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0034 0.0126
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0035 0.011
Plasmodium vivax JmjC domain containing protein 0.002 0.0015 0.0064
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0195 0.0706
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0025 0.0214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Mycobacterium tuberculosis Probable reductase 0.0109 0.0191 0.1332
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0051 0.0179
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.004
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0052 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0121
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0023 0.042
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0339 0.1243
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0054 0.0483
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0006 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Brugia malayi nuclear hormone receptor 0.0015 0.0006 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0027 0.01
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Brugia malayi ecdysteroid receptor 0.0032 0.0039 0.0038
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0039 0.0145
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0038 0.0323
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0032 0.0276
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3247 0.6329 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0027 0.0201
Onchocerca volvulus 0.0118 0.0208 0.0203
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0038 0.0139
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.001 0.0018
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0035
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0118 0.0208 0.2258
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0039 0.0145
Echinococcus granulosus cathepsin L 0.0259 0.0484 0.1793
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0039 0.0039
Brugia malayi RNA, U transporter 1 0.0099 0.0171 0.017
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Brugia malayi TAR-binding protein 0.0076 0.0126 0.0126
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0106 0.0713
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0466 0.0888 0.1404
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0052 0.0052
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.0629 0.0994
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0142 0.0525
Brugia malayi hypothetical protein 0.0036 0.0048 0.0047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0325 0.0613 0.532
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0043 0.102
Toxoplasma gondii thioredoxin reductase 0.0048 0.0071 0.0664
Trypanosoma brucei trypanothione reductase 0.0048 0.0071 0.0719
Onchocerca volvulus 0.01 0.0172 0.0167
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Brugia malayi CXXC zinc finger family protein 0.0035 0.0045 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0023 0.0234
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0118 0.0208 0.2258
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0079 0.0805
Loa Loa (eye worm) hypothetical protein 0.0052 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Loa Loa (eye worm) hypothetical protein 0.0055 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0466 0.0888 0.8371
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0208 0.1938
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0039 0.0127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0023 0.0176
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0039 0.0145
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0191 0.1332
Giardia lamblia PHD finger protein 15 0.006 0.0095 0.0885
Loa Loa (eye worm) hypothetical protein 0.0599 0.1149 0.1149
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.001 0.0036
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0051 0.0172
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Plasmodium falciparum thioredoxin reductase 0.0048 0.0071 0.0697
Schistosoma mansoni lamin 0.0055 0.0084 0.0292
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0071 0.0262
Plasmodium falciparum phd finger protein, putative 0.006 0.0095 0.0975
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0039 0.0145
Brugia malayi AF-10 protein 0.002 0.0015 0.0015
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0025 0.0118
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0023 0.0176
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0339 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0259 0.0484 0.1785

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.