Detailed information for compound 1742848

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1244.53 | Formula: C60H85N13O12S2
  • H donors: 15 H acceptors: 12 LogP: 3.34 Rotable bonds: 35
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCCCC(C(=O)NCC(=O)NCC(=O)N[C@@H](C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)c1ccc(cc1)O)Cc1c[nH]c2c1cccc2)CCCCN)C(=O)N[C@H](C(=O)N)[C@H](O)C)Cc1ccccc1)N
  • InChi: 1S/C60H85N13O12S2/c1-3-4-5-6-7-8-9-13-21-42(62)54(79)66-32-49(76)65-33-50(77)67-45(29-37-18-11-10-12-19-37)56(81)71-48-35-87-86-34-47(58(83)72-51(36(2)74)53(63)78)70-55(80)44(23-16-17-28-61)68-57(82)46(30-39-31-64-43-22-15-14-20-41(39)43)69-60(85)52(73-59(48)84)38-24-26-40(75)27-25-38/h10-12,14-15,18-20,22,24-27,31,36,42,44-48,51-52,64,74-75H,3-9,13,16-17,21,23,28-30,32-35,61-62H2,1-2H3,(H2,63,78)(H,65,76)(H,66,79)(H,67,77)(H,68,82)(H,69,85)(H,70,80)(H,71,81)(H,72,83)(H,73,84)/t36-,42?,44+,45-,46-,47+,48+,51+,52+/m1/s1
  • InChiKey: ZNBROLHRVAGMPW-VZAIERFQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Schistosoma mansoni nAChR subunit 0.0021 0.0053 0.0071
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0022 0.0027
Onchocerca volvulus 0.0021 0.0053 0.0134
Mycobacterium tuberculosis Conserved protein 0.0073 0.0378 0.0428
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.0338 0.0377
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.007 0.129
Mycobacterium leprae Probable lipase LipE 0.0073 0.0378 0.1507
Echinococcus multilocularis Mastin 0.0028 0.0097 0.0092
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0018
Plasmodium falciparum transporter, putative 0.0087 0.0464 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0067 0.0338 0.0421
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0013 0.0001
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0061 0.0064
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0023 0.01
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.0516 0.0579
Echinococcus multilocularis sodium and chloride dependent glycine 0.0087 0.0464 0.046
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0223 0.0247
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus multilocularis muscleblind protein 0.0145 0.0821 0.0817
Trypanosoma brucei polo-like protein kinase 0.0096 0.0516 0.2772
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0173
Brugia malayi putative neuropeptide receptor NPR1 0.0067 0.0338 0.0418
Entamoeba histolytica hypothetical protein 0.0023 0.007 0.008
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Onchocerca volvulus 0.0014 0.0013 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0315 0.0437
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0067 0.0338 0.0469
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0279 0.0275
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0509 0.0504
Loa Loa (eye worm) hypothetical protein 0.0041 0.0177 0.0215
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.0338 0.0469
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0021 0.0053 0.0049
Echinococcus granulosus metabotropic glutamate receptor 5 0.047 0.2823 0.319
Trypanosoma cruzi ISWI complex protein 0.0015 0.002 0.0012
Entamoeba histolytica hypothetical protein 0.0073 0.0375 0.0497
Schistosoma mansoni amine GPCR 0.0067 0.0338 0.0469
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0014 0.0013 0.0009
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0087 0.0464 0.0645
Onchocerca volvulus 0.0087 0.0464 0.1467
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0321
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0309 0.183 1
Echinococcus multilocularis nmda type glutamate receptor 0.0054 0.026 0.0255
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0375 0.0419
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0012 0.0007
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0375 0.0521
Schistosoma mansoni zinc finger protein 0.0015 0.002 0.0025
Brugia malayi hypothetical protein 0.0028 0.0097 0.0109
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0218 0.0233
Brugia malayi follicle stimulating hormone receptor 0.0067 0.0338 0.0418
Loa Loa (eye worm) ACC-1 protein 0.0021 0.0053 0.0057
Brugia malayi beta-lactamase family protein 0.0073 0.0378 0.0469
Loa Loa (eye worm) hypothetical protein 0.128 0.7814 1
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0014 0.0013 0.0001
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0067 0.0338 0.0377
Schistosoma mansoni nAChR subunit 0.0021 0.0053 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.0516 0.0511
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0046 0.0047
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0078 0.0409 0.0405
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.0338 0.0469
Entamoeba histolytica hypothetical protein 0.0073 0.0375 0.0497
Echinococcus granulosus glycine receptor subunit alpha 1 0.0021 0.0053 0.0055
Schistosoma mansoni nAChR subunit 0.0021 0.0053 0.0071
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0416 0.249 0.3479
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0021 0.0053 0.0049
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0035 0.0033
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0024 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0218 0.0233
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0028 0.0097 0.0109
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0302 0.0419
Leishmania major hypothetical protein, conserved 0.0015 0.002 0.0047
Schistosoma mansoni tyrosine kinase 0.0055 0.0265 0.0368
Onchocerca volvulus 0.0067 0.0338 0.1057
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0279 0.0343
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0144 0.015
Brugia malayi G-protein coupled receptor 0.0067 0.0338 0.0418
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0378 0.0374
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0067 0.0338 0.0469
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Brugia malayi larval opioid receptor 0.0067 0.0338 0.0418
Loa Loa (eye worm) hypothetical protein 0.0047 0.0218 0.0268
Echinococcus multilocularis G protein coupled receptor 139 0.0067 0.0338 0.0333
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.007 1
Echinococcus granulosus twitchin 0.0013 0.0007 0.0002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0067 0.0338 0.0333
Toxoplasma gondii aldehyde dehydrogenase 0.0194 0.1121 1
Echinococcus granulosus neuropeptide receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) acetylcholine receptor protein 0.0014 0.0013 0.0005
Echinococcus granulosus kinesin family 1 0.02 0.1159 0.1307
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0021 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0144 0.2925
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0279 0.1471
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0021 0.0053 0.0049
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.0516 0.0646
Echinococcus granulosus enteropeptidase 0.0028 0.0097 0.0105
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0378 0.0415
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0067 0.0338 0.0377
Echinococcus granulosus transmembrane protease serine 3 0.0028 0.0097 0.0105
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.0516 0.2772
Brugia malayi hypothetical protein 0.0087 0.0464 0.0579
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0019
Schistosoma mansoni hypothetical protein 0.0015 0.002 0.0025
Brugia malayi Muscleblind-like protein 0.0145 0.0821 0.1037
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0147 0.0835 0.1059
Brugia malayi STAT protein, DNA binding domain containing protein 0.016 0.0911 0.1153
Schistosoma mansoni sodium-dependent amino acid transporter 0.0087 0.0464 0.0645
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0067 0.0338 0.0469
Loa Loa (eye worm) hypothetical protein 0.0157 0.0892 0.1132
Brugia malayi jmjC domain containing protein 0.0016 0.0024 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0067 0.0338 0.0333
Echinococcus granulosus g protein coupled receptor 0.0067 0.0338 0.0377
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0022 0.002
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0304 0.0299
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0218 0.0264
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.0338 0.0469
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0055 0.0265 0.0822
Brugia malayi G protein-coupled receptor 0.0067 0.0338 0.0418
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus multilocularis neuropeptide s receptor 0.0067 0.0338 0.0333
Brugia malayi GnHR receptor homolog 0.0067 0.0338 0.0418
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0516 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0024 0.002
Brugia malayi PHD-finger family protein 0.0027 0.009 0.01
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0067 0.0338 0.0418
Toxoplasma gondii hypothetical protein 0.005 0.0233 0.1997
Loa Loa (eye worm) beta-lactamase 0.0073 0.0378 0.0473
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0218 0.0847
Echinococcus granulosus glycine receptor subunit alpha 1 0.0021 0.0053 0.0055
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0821 0.0817
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0338 0.0377
Schistosoma mansoni hypothetical protein 0.0093 0.0502 0.0698
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus multilocularis fmrfamide receptor 0.0067 0.0338 0.0333
Plasmodium falciparum amino acid transporter, putative 0.0087 0.0464 1
Loa Loa (eye worm) hypothetical protein 0.0127 0.0707 0.0894
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0338 0.0377
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0827 0.1115
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Echinococcus granulosus muscleblind protein 0.0145 0.0821 0.0924
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0021 0.0053 0.0049
Echinococcus multilocularis tyrosine kinase 0.0055 0.0265 0.0261
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0004
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Onchocerca volvulus 0.0083 0.0438 0.1383
Onchocerca volvulus Neuropeptide F receptor homolog 0.0067 0.0338 0.1057
Brugia malayi Trypsin family protein 0.0028 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Onchocerca volvulus 0.0073 0.0378 0.1188
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0067 0.0338 0.0333
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.0338 0.0333
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0028 0.0097 0.0092
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Onchocerca volvulus 0.0067 0.0338 0.1057
Onchocerca volvulus 0.0057 0.0276 0.0857
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0022 0.002
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0244 0.1428 0.1424
Loa Loa (eye worm) melatonin receptor type 1A 0.0067 0.0338 0.0421
Onchocerca volvulus 0.0021 0.0053 0.0134
Brugia malayi Dopamine receptor protein 2 0.0067 0.0338 0.0418
Echinococcus multilocularis tissue type plasminogen activator 0.0057 0.0276 0.0272
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0509 0.0571
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0194 0.0249
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Schistosoma mansoni voltage-gated potassium channel 0.0086 0.0454 0.0631
Loa Loa (eye worm) hypothetical protein 0.0514 0.3093 0.3952
Onchocerca volvulus 0.0193 0.1117 0.3586
Onchocerca volvulus 0.0067 0.0338 0.1057
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0023 0.0246
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0023 0.0066 0.007
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0687 0.0868
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0144 0.1877
Loa Loa (eye worm) hypothetical protein 0.0044 0.0199 0.0243
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0021 0.0053 0.0055
Schistosoma mansoni jumonji domain containing protein 0.006 0.0293 0.0407
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0283 0.167 0.2126
Loa Loa (eye worm) TYRA-2 protein 0.0067 0.0338 0.0421
Schistosoma mansoni opsin-like receptor 0.0067 0.0338 0.0469
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0378 0.7258
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0067 0.0338 0.0377
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0024 0.0017
Trypanosoma cruzi ISWI complex protein 0.0015 0.002 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.0087 0.0464 0.0645
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0021 0.0053 0.0057
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0053 0.0053
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0021 0.0053 0.0049
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0087 0.0464 0.0645
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.4076
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0061 0.0269
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.0516 0.0649
Onchocerca volvulus 0.0067 0.0338 0.1057
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0023 0.01
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0053 0.0071
Echinococcus granulosus cpg binding protein 0.0032 0.0125 0.0137
Echinococcus granulosus allatostatin A receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0338 0.0377
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0127 0.0707 0.0894
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.0863 0.1091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.007 0.0321
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0024 0.0019
Mycobacterium ulcerans lipase LipD 0.0073 0.0378 0.0415
Echinococcus granulosus tachykinin peptides receptor 99D 0.0067 0.0338 0.0377
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.1446 0.8839 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0087 0.0464 0.0645
Echinococcus multilocularis thymidine phosphorylase 0.1446 0.8839 0.8839
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.1121 0.1564
Schistosoma mansoni hypothetical protein 0.0073 0.0375 0.0521
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.0579
Brugia malayi Trypsin family protein 0.0028 0.0097 0.0109
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0378 0.8099
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0067 0.0338 0.0421
Brugia malayi Guanylyl cyclase protein 23 0.0055 0.0265 0.0325
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0067 0.0338 0.0377
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0073
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0218 0.0233
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0223 0.0247
Loa Loa (eye worm) RGC/RGC protein kinase 0.0055 0.0265 0.0328
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0218 0.1132
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0438 0.0434
Loa Loa (eye worm) RGC/RGC protein kinase 0.0055 0.0265 0.0328
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0023 0.0246
Onchocerca volvulus Poor gastrulation protein homolog 0.0093 0.0502 0.159
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.007 0.0066
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0378 0.0428
Mycobacterium ulcerans hypothetical protein 0.0028 0.0097 0.0096
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0378 0.0428
Echinococcus multilocularis somatostatin receptor 0.0067 0.0338 0.0333
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0132 0.015
Onchocerca volvulus 0.0028 0.0097 0.0276
Schistosoma mansoni biogenic amine receptor 0.0067 0.0338 0.0469
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0021 0.0053 0.0057
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0061 0.097
Schistosoma mansoni cpg binding protein 0.0032 0.0125 0.0172
Loa Loa (eye worm) hypothetical protein 0.0145 0.0821 0.1041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0304 0.0339
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0113
Loa Loa (eye worm) hypothetical protein 0.0145 0.0821 0.1041
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0321
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0293 0.0289
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0078 0.0409 0.0458
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0021 0.0053 0.0055
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0223 0.0274
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0067 0.0338 0.0469
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0067 0.0338 0.0418
Onchocerca volvulus 0.0514 0.3093 1
Echinococcus multilocularis geminin 0.0176 0.1009 0.1005
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.007 0.0526
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.0338 0.0333
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0021 0.0053 0.0055
Loa Loa (eye worm) oxidoreductase 0.0014 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0218 0.0233
Echinococcus multilocularis GPCR, family 3, C terminal 0.0093 0.0502 0.0497
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0067 0.0338 0.0469
Echinococcus granulosus roundabout 2 0.0016 0.0025 0.0023
Echinococcus granulosus glycoprotein Antigen 5 0.0028 0.0097 0.0105
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.0863 0.1094
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0147 0.0162
Brugia malayi G protein-coupled receptor F59B2.13 0.0067 0.0338 0.0418
Echinococcus granulosus glycine receptor subunit beta 0.0021 0.0053 0.0055
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0194 0.1002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0378 0.0525
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0067 0.0338 0.0333
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0066 0.0089
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.0583
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0378 0.0423
Schistosoma mansoni biogenic amine receptor 0.0067 0.0338 0.0469
Schistosoma mansoni nAChR subunit 0.0021 0.0053 0.0071
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0031 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0061 0.0066
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0321
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0014 0.0013 0.0009
Onchocerca volvulus 0.0028 0.0097 0.0276
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.007 0.0031
Echinococcus granulosus receptor type guanylyl cyclase 0.0055 0.0265 0.0295
Onchocerca volvulus 0.0055 0.0265 0.0822
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0516 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0464 0.0583
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0218 0.0281
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Loa Loa (eye worm) solute carrier family 6 member 4 0.0514 0.3093 0.3952
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0021 0.0053 0.0057
Echinococcus granulosus somatostatin receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0173
Echinococcus granulosus neuropeptide FF receptor 2 0.0067 0.0338 0.0377
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0061
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0022 0.0017
Echinococcus granulosus sodium and chloride dependent glycine 0.0087 0.0464 0.052
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0061 0.1082
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0218 0.0264
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0053 0.0053
Onchocerca volvulus 0.0028 0.0097 0.0276
Onchocerca volvulus 0.0028 0.0097 0.0276
Plasmodium vivax amine transporter, putative 0.0087 0.0464 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0067 0.0338 0.0333
Echinococcus multilocularis cpg binding protein 0.0032 0.0125 0.0121
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0012 0.0008
Echinococcus granulosus 7TM GPCR rhodopsin 0.0067 0.0338 0.0377
Brugia malayi jmjC domain containing protein 0.0016 0.0024 0.0016
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0016 0.0022 0.002
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0218 0.0264
Onchocerca volvulus 0.0067 0.0338 0.1057
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0061 0.0269
Echinococcus multilocularis glutamate receptor 2 0.0054 0.026 0.0255
Echinococcus granulosus dnaJ subfamily B 0.041 0.245 0.2768
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.0338 0.0377
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0012 0.0013
Echinococcus granulosus dro:myosuppressin receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) hypothetical protein 0.0073 0.0378 0.0473
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0054 0.026 0.0255
Onchocerca volvulus 0.0028 0.0097 0.0276
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0218 0.0847
Trypanosoma cruzi hypothetical protein, conserved 0.1201 0.7327 1
Echinococcus multilocularis glycoprotein Antigen 5 0.0028 0.0097 0.0092
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0279 0.0316
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0516 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0053 0.0053
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0022 0.0199
Echinococcus multilocularis nAChR subunit 0.0021 0.0053 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0464 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0218 0.0246
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0293 0.0289
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.0338 0.0377
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0067 0.0338 0.0421
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0093 0.0502 0.159
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.0338 0.0333
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0014 0.0015 0.0007
Onchocerca volvulus 0.0087 0.0464 0.1467
Brugia malayi hypothetical protein 0.0014 0.0013 0.0001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0087 0.0464 0.0645
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0567 0.0711
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0023 0.0018
Onchocerca volvulus 0.0067 0.0338 0.1057
Brugia malayi hypothetical protein 0.0054 0.026 0.0318
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0087 0.0464 0.052
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0256 0.0316
Leishmania major hypothetical protein, conserved 0.0057 0.0276 0.1453
Brugia malayi sulfakinin receptor protein 0.0067 0.0338 0.0418
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0132 0.015
Echinococcus granulosus g protein coupled receptor 0.0067 0.0338 0.0377
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.0338 0.0469
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0022 0.0027
Echinococcus multilocularis serotonin transporter 0.0514 0.3093 0.309
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0514 0.3093 0.4323
Schistosoma mansoni hypothetical protein 0.0048 0.0223 0.0308
Brugia malayi Trypsin-like protease protein 5 0.0028 0.0097 0.0109
Schistosoma mansoni hypothetical protein 0.0057 0.0276 0.0383
Brugia malayi jmjC domain containing protein 0.0016 0.0024 0.0016
Schistosoma mansoni nAChR subunit 0.0021 0.0053 0.0071
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.0579
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0408 0.2442 0.2753
Onchocerca volvulus 0.0067 0.0338 0.1057
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0031 0.003
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.0338 0.0421
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0067 0.0338 0.0333
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.0338 0.0333
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0132 0.015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.0338 0.0333
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0408 0.2442 1
Onchocerca volvulus 0.0067 0.0338 0.1057
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0194 0.1121 0.1117
Onchocerca volvulus Huntingtin homolog 0.0127 0.0707 0.2254
Echinococcus multilocularis enteropeptidase 0.0028 0.0097 0.0092
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0276 0.0361
Toxoplasma gondii kringle domain-containing protein 0.0057 0.0276 0.2382
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Loa Loa (eye worm) hypothetical protein 0.0073 0.0378 0.0473
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Brugia malayi Cyclic-nucleotide gated cation channel 0.0016 0.0022 0.0013
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0012 0.0013
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0132
Schistosoma mansoni sodium/chloride dependent transporter 0.0088 0.0466 0.0648
Schistosoma mansoni ap endonuclease 0.0022 0.0061 0.0082
Schistosoma mansoni biogenic amine receptor 0.0067 0.0338 0.0469
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Schistosoma mansoni hypothetical protein 0.0048 0.0223 0.0308
Brugia malayi AKH receptor 0.0067 0.0338 0.0418
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0218 0.1132
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0378 0.7265
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0061 0.1082
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0408 0.2442 0.2763
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0013 0.0001
Loa Loa (eye worm) hypothetical protein 0.0514 0.3093 0.3952
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.0338 0.0469
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0509 0.0708
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0113
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0021 0.0053 0.0049
Loa Loa (eye worm) hypothetical protein 0.0068 0.0346 0.0431
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0067 0.0338 0.0469
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0194 0.1121 0.1268
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Schistosoma mansoni hypothetical protein 0.0028 0.0097 0.0132
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0173
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0338 0.0377
Plasmodium falciparum cysteine repeat modular protein 1 0.0057 0.0276 0.5842
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0054 0.026 0.0255
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.0509 0.0637
Schistosoma mansoni acetylcholine receptor subunit beta 0.0014 0.0013 0.0014
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0035 0.0035
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.0338 0.0377
Echinococcus multilocularis neuropeptide receptor A26 0.0067 0.0338 0.0333
Echinococcus multilocularis metabotropic glutamate receptor 5 0.047 0.2823 0.282
Trypanosoma cruzi extracellular receptor, putative 0.0054 0.026 0.0339
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0014 0.0013 0.0005
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0021 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0067 0.0338 0.0469
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0516 1
Echinococcus granulosus neuropeptide s receptor 0.0067 0.0338 0.0377
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.0516 0.0689
Loa Loa (eye worm) hypothetical protein 0.0073 0.0378 0.0473
Toxoplasma gondii hypothetical protein 0.0087 0.0464 0.4076
Echinococcus granulosus G protein coupled receptor 139 0.0067 0.0338 0.0377
Echinococcus granulosus serotonin receptor 0.0067 0.0338 0.0377
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0021 0.0053 0.0049
Onchocerca volvulus 0.0067 0.0338 0.1057
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0024 0.0272
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0012 0.0013
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0087 0.0464 0.046
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0022 0.0017
Schistosoma mansoni alpha-1 adrenergic receptor 0.0067 0.0338 0.0469
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.0338 0.0377
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0021 0.0053 0.0053
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0067 0.0338 0.0421
Echinococcus multilocularis zinc finger protein 0.0021 0.0057 0.0052
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0028 0.0097 0.0105
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Loa Loa (eye worm) STAT protein 0.016 0.0911 0.1156
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0023 0.0018
Loa Loa (eye worm) hypothetical protein 0.0048 0.0223 0.0274
Brugia malayi hypothetical protein 0.0014 0.0013 0.0001
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0024 0.0111
Brugia malayi beta-lactamase family protein 0.0073 0.0378 0.0469
Brugia malayi Dopamine receptor 0.0067 0.0338 0.0418
Echinococcus multilocularis neuropeptide receptor 0.0067 0.0338 0.0333
Trypanosoma brucei ISWI complex protein 0.0015 0.002 0.0047
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.0338 0.0469
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0218 0.0233
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0509 0.0571
Brugia malayi Kringle domain containing protein 0.0057 0.0276 0.0339
Brugia malayi neuropeptide F receptor 0.0067 0.0338 0.0418
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Brugia malayi Cation transporter family protein 0.0021 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0378 0.0501
Echinococcus multilocularis kinesin family 1 0.02 0.1159 0.1155
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0054 0.026 0.0255
Loa Loa (eye worm) hypothetical protein 0.0073 0.0378 0.0473
Echinococcus multilocularis allatostatin A receptor 0.0067 0.0338 0.0333
Echinococcus granulosus thymidine phosphorylase 0.1446 0.8839 1
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0054 0.026 0.0318
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.0583
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0378 0.0428
Echinococcus multilocularis fmrfamide receptor 0.0067 0.0338 0.0333
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.0338 0.0469
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0023 0.0026
Schistosoma mansoni neurotransmitter gated ion channel 0.0014 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0048 0.0223 0.0308
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.0338 0.0377
Schistosoma mansoni bromodomain containing protein 0.0065 0.0326 0.0452
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Leishmania major extracellular receptor, putative 0.0054 0.026 0.1363
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Brugia malayi Serotonin receptor 0.0067 0.0338 0.0418
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0087 0.0464 0.0645
Schistosoma mansoni voltage-gated potassium channel 0.0086 0.0454 0.0631
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0087 0.0464 0.0583
Echinococcus multilocularis g protein coupled receptor 0.0067 0.0338 0.0333
Brugia malayi excitatory GABA receptor EXP-1A 0.0021 0.0053 0.0053
Toxoplasma gondii ABC1 family protein 0.0073 0.0378 0.3302
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0021 0.0053 0.0049
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.007 0.0526
Leishmania major mitochondrial DNA polymerase beta 0.0309 0.183 1
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0087 0.0464 0.0583
Brugia malayi hypothetical protein 0.0014 0.0013 0.0001
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0087 0.0464 1
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0378 0.0501
Echinococcus multilocularis neuropeptide receptor 0.0067 0.0338 0.0333
Onchocerca volvulus 0.0014 0.0013 0.0003
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0024 0.0022
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.007 0.0079
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0018
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0023 0.0061
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0021 0.0053 0.0055
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0053 0.0053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0035 0.0031
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0061 0.097
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.007 0.0066
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0144 0.2925
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0087 0.0464 0.046
Loa Loa (eye worm) LGC-31 protein 0.0021 0.0053 0.0057
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0194 0.0249
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0054 0.026 0.0289
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0516 0.0689
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0104 0.0567 0.0714
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0516 1
Echinococcus granulosus glycine receptor subunit beta 0.0021 0.0053 0.0055
Onchocerca volvulus 0.0067 0.0338 0.1057
Echinococcus granulosus hypothetical protein 0.0067 0.0338 0.0377
Schistosoma mansoni kinase 0.0049 0.0226 0.0313
Brugia malayi isocitrate dehydrogenase 0.0016 0.0023 0.0014
Echinococcus granulosus sodium and chloride dependent glycine 0.0087 0.0464 0.052
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0023 0.0014
Brugia malayi Melatonin receptor type 1A 0.0067 0.0338 0.0418
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0053 0.0053
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0023 0.0018
Echinococcus granulosus alpha 1A adrenergic receptor 0.0067 0.0338 0.0377
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0061 0.0067
Echinococcus granulosus neuropeptide receptor 0.0067 0.0338 0.0377
Schistosoma mansoni amine GPCR 0.0067 0.0338 0.0469
Echinococcus multilocularis GPCR, family 2 0.0048 0.0223 0.0218
Echinococcus granulosus fmrfamide receptor 0.0067 0.0338 0.0377
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus multilocularis glycine receptor subunit beta 0.0021 0.0053 0.0049
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0378 0.2014
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0218 0.0246
Loa Loa (eye worm) hypothetical protein 0.0514 0.3093 0.3952
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0113
Loa Loa (eye worm) TK/ROR protein kinase 0.006 0.0298 0.037
Schistosoma mansoni hypothetical protein 0.0028 0.0097 0.0132
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) hypothetical protein 0.0179 0.1031 0.1309
Loa Loa (eye worm) hypothetical protein 0.0087 0.0464 0.0583
Schistosoma mansoni histamine h1 receptor 0.0067 0.0338 0.0469
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0012 0.0013
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0087 0.0464 0.0645
Brugia malayi Protein kinase domain containing protein 0.0058 0.0282 0.0346
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0827 0.4485
Echinococcus granulosus GPCR family 3 C terminal 0.0093 0.0502 0.0563
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0378 0.7265
Schistosoma mansoni protein kinase 0.0055 0.0265 0.0368
Onchocerca volvulus 0.0018 0.0036 0.0077
Brugia malayi putative neuropeptide receptor 0.0067 0.0338 0.0418
Echinococcus multilocularis G-protein coupled receptor, putative 0.0067 0.0338 0.0333
Treponema pallidum sodium- and chloride- dependent transporter 0.0514 0.3093 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0025 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0516 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0075 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0021 0.0053 0.0053
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.0338 0.0377
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0075 0.0071
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus granulosus phd:f box containing protein 0.0016 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0104 0.0121
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0061 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0067 0.0338 0.0418
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0378 0.0525
Loa Loa (eye worm) hypothetical protein 0.0087 0.0464 0.0583
Brugia malayi hypothetical protein 0.0127 0.0707 0.089
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0024 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0019
Echinococcus granulosus neuropeptide receptor A26 0.0067 0.0338 0.0377
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0132 0.015
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0468 0.2812 0.3182
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.0338 0.0333
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Giardia lamblia Kinase, PLK 0.0096 0.0516 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0061 0.0067
Onchocerca volvulus 0.0067 0.0338 0.1057
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0438 0.0546
Echinococcus multilocularis roundabout 2 0.0016 0.0025 0.002
Entamoeba histolytica hypothetical protein 0.0073 0.0375 0.0497
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0093 0.0502 0.0628
Schistosoma mansoni hypothetical protein 0.0174 0.0999 0.1394
Onchocerca volvulus 0.0014 0.0013 0.0003
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0014 0.0013 0.0001
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0067 0.0338 0.0469
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0021 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0193 0.1117 0.142
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0022 0.0027
Onchocerca volvulus 0.0193 0.1117 0.3586
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0827 0.4485
Schistosoma mansoni neuropeptide f receptor 76f 0.0067 0.0338 0.0469
Loa Loa (eye worm) hypothetical protein 0.0057 0.0276 0.0342
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Mycobacterium ulcerans thymidine phosphorylase 0.1446 0.8839 1
Schistosoma mansoni ap endonuclease 0.0022 0.0061 0.0082
Entamoeba histolytica hypothetical protein 0.0054 0.026 0.0339
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0378 0.7258
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.1121 0.1256
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0016 0.0022 0.0017
Echinococcus multilocularis dnaJ subfamily B 0.041 0.245 0.2447
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0022 0.0017
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0378 0.0415
Brugia malayi beta-lactamase 0.0073 0.0378 0.0469
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0378 0.0428
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Schistosoma mansoni adenoreceptor 0.0067 0.0338 0.0469
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0315 0.0437
Trichomonas vaginalis esterase, putative 0.0073 0.0378 0.7265
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0024 0.0019
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0054 0.026 0.0255
Schistosoma mansoni hypothetical protein 0.0067 0.0338 0.0469
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Loa Loa (eye worm) hypothetical protein 0.0093 0.0502 0.0631
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0012 0.0013
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0022 0.0027
Onchocerca volvulus 0.0047 0.0218 0.0668
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0067 0.0338 0.1057
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0024 0.003
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Loa Loa (eye worm) kinesin-like protein KLP2 0.0026 0.0086 0.0099
Loa Loa (eye worm) hypothetical protein 0.0073 0.0378 0.0473
Brugia malayi Serotonin receptor 0.0067 0.0338 0.0418
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Mycobacterium leprae conserved hypothetical protein 0.0023 0.007 0.024
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.0516 0.1635
Toxoplasma gondii kinesin motor domain-containing protein 0.0026 0.0086 0.0673
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Loa Loa (eye worm) hypothetical protein 0.0152 0.0863 0.1094
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0087 0.0464 0.052
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0378 0.1507
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0021 0.0053 0.0049
Brugia malayi RE15519p 0.0067 0.0338 0.0418
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0024 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0054 0.026 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0338 0.0377
Schistosoma mansoni tyrosine kinase 0.0055 0.0265 0.0368
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0315 0.0352
Onchocerca volvulus 0.0067 0.0338 0.1057
Echinococcus multilocularis glycine receptor subunit beta 0.0021 0.0053 0.0049
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0092
Schistosoma mansoni acetylcholine receptor-related 0.0014 0.0013 0.0014
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0132
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0218 0.0268
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0378 0.0469
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0193 0.1117 0.1559
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0053 0.0053
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0024 0.0017
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0147 0.0143
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0022 0.002
Mycobacterium ulcerans hypothetical protein 0.0073 0.0378 0.0415
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.0509 0.064
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0218 0.1132
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.007 0.129
Toxoplasma gondii hypothetical protein 0.0087 0.0464 0.4076
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0067 0.0338 0.0418
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0031 0.004
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0016 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0071 0.0362 0.0452
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0021 0.0053 0.0055
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0021 0.0053 0.0055
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0013 0.0009 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0024 0.0019
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0014 0.0013 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0516 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0075 0.008
Echinococcus multilocularis sodium and chloride dependent glycine 0.0087 0.0464 0.046
Schistosoma mansoni cell adhesion molecule 0.0013 0.0009 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0066 0.0089
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0514 0.3093 0.395
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0293 0.0327
Schistosoma mansoni amine GPCR 0.0067 0.0338 0.0469
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0012 0.0004
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0012 0.0004
Brugia malayi jmjC domain containing protein 0.006 0.0293 0.0361
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0035 0.0046
Onchocerca volvulus 0.0157 0.0892 0.2857
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Echinococcus granulosus geminin 0.0176 0.1009 0.1137
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0218 0.0281
Brugia malayi Metabotropic glutamate receptor precursor. 0.0337 0.2004 0.2553
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0144 0.0163
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.0338 0.0421
Brugia malayi Tachykinin-like peptides receptor 99D 0.0067 0.0338 0.0418
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Schistosoma mansoni cpg binding protein 0.0032 0.0125 0.0172
Echinococcus granulosus glycine receptor subunit alpha 1 0.0021 0.0053 0.0055
Schistosoma mansoni zinc finger protein 0.0021 0.0057 0.0076
Schistosoma mansoni hypothetical protein 0.0104 0.0567 0.0789
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0046 0.0041
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0021 0.0053 0.0071
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0013 0.0001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.0579
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0338 0.0377
Echinococcus granulosus sex peptide receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.0019
Schistosoma mansoni hypothetical protein 0.0176 0.1009 0.1408
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0279 0.0303
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0321
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0024 0.0111
Schistosoma mansoni metabotropic glutamate receptor 0.0244 0.1428 0.1994
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0509 0.0504
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0067 0.0338 0.0333
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0061 0.0055
Plasmodium vivax kinesin-5 0.0026 0.0086 0.165
Schistosoma mansoni kinesin eg-5 0.0026 0.0086 0.0117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0087 0.0464 0.052
Echinococcus granulosus metabotropic glutamate receptor 2 0.0244 0.1428 0.1612
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0053 0.0057
Onchocerca volvulus Huntingtin homolog 0.0127 0.0707 0.2254
Brugia malayi hypothetical protein 0.0014 0.0013 0.0001
Mycobacterium tuberculosis Conserved protein 0.0073 0.0378 0.0428
Schistosoma mansoni hypothetical protein 0.0021 0.0053 0.0071
Echinococcus multilocularis serotonin receptor 0.0067 0.0338 0.0333
Schistosoma mansoni neurotransmitter gated ion channel 0.0014 0.0013 0.0014
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0087 0.0464 0.0645
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0035 0.0046
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0279 0.0303
Echinococcus granulosus g-protein coupled receptor 0.0067 0.0338 0.0377
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0321
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0014 0.0013 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.0338 0.0469
Loa Loa (eye worm) RGC/RGC protein kinase 0.0055 0.0265 0.0328
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0012 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.0338 0.0333
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0014 0.0013 0.0001
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0516 0.0689
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0018
Brugia malayi neuropeptide F receptor 0.0067 0.0338 0.0418
Echinococcus multilocularis transmembrane protease serine 3 0.0028 0.0097 0.0092
Schistosoma mansoni sodium/chloride dependent transporter 0.0514 0.3093 0.4323
Brugia malayi hypothetical protein 0.0014 0.0013 0.0001
Leishmania major hypothetical protein, conserved 0.0073 0.0378 0.2014
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0061 0.0063
Leishmania major hypothetical protein, conserved 0.0016 0.0024 0.0068
Echinococcus granulosus g protein coupled receptor 0.0067 0.0338 0.0377
Schistosoma mansoni hypothetical protein 0.041 0.245 0.3424
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0194 0.0249
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0067 0.0338 0.0333
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0378 0.0428
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Brugia malayi Cation transporter family protein 0.0021 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0113
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0173
Loa Loa (eye worm) norepinephrine transporter 0.0514 0.3093 0.3952
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0378 0.0428
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0378 0.0428
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.0338 0.0333
Loa Loa (eye worm) hypothetical protein 0.0193 0.1117 0.142
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0066 0.007
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0378 0.7265
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0218 0.0233
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0024 0.002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0375 0.0371
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0078 0.0409 0.0513
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Brugia malayi Bromodomain containing protein 0.0038 0.0162 0.0192
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0022 0.0027
Schistosoma mansoni vesicular amine transporter 0.0015 0.002 0.0025
Schistosoma mansoni myosin xvIII 0.0067 0.0338 0.0469
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.0338 0.0377
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0378 0.7265
Brugia malayi Cation transporter family protein 0.0193 0.1117 0.1416
Echinococcus multilocularis serotonin receptor 0.0067 0.0338 0.0333
Schistosoma mansoni hypothetical protein 0.0067 0.0338 0.0469
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0024 0.002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0253 0.0329
Schistosoma mansoni metabotropic glutamate receptor 0.1173 0.7152 1
Mycobacterium ulcerans hypothetical protein 0.0163 0.0929 0.1039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0173
Schistosoma mansoni cpg binding protein 0.0029 0.0104 0.0141
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.1121 0.1256
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0022 0.0017
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Echinococcus granulosus GPCR family 2 0.0048 0.0223 0.0247
Echinococcus granulosus tissue type plasminogen activator 0.0057 0.0276 0.0307
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0014 0.0013 0.0008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0223 0.0218
Onchocerca volvulus 0.0193 0.1117 0.3586
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.183 0.2486
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0321
Schistosoma mansoni hypothetical protein 0.0048 0.0223 0.0308
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0054 0.026 0.0321
Loa Loa (eye worm) serotonin transporter b 0.0514 0.3093 0.3952
Echinococcus granulosus atrial natriuretic peptide receptor 0.0054 0.026 0.0289
Loa Loa (eye worm) hypothetical protein 0.0014 0.0012 0.0004
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0687 0.0868
Echinococcus multilocularis g protein coupled receptor 0.0067 0.0338 0.0333
Onchocerca volvulus 0.0029 0.0104 0.0297
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0067 0.0338 0.0333
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0023 0.0029
Entamoeba histolytica hypothetical protein 0.1201 0.7327 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.0055 0.0265 0.0261
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0021 0.0053 0.0053
Onchocerca volvulus 0.0067 0.0338 0.1057
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.0863 0.1091
Loa Loa (eye worm) hypothetical protein 0.047 0.2823 0.3606
Echinococcus multilocularis orexin receptor type 2 0.0067 0.0338 0.0333
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0132
Brugia malayi G-protein coupled receptor 0.0067 0.0338 0.0418
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0028 0.0097 0.0105
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0193 0.1117 0.1559
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.1121 0.1564
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0066 0.0062
Schistosoma mansoni amine GPCR 0.0067 0.0338 0.0469
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0218 0.0281
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Echinococcus multilocularis dro:myosuppressin receptor 0.0067 0.0338 0.0333
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Loa Loa (eye worm) glutamate receptor 0.0226 0.1321 0.1681
Echinococcus multilocularis g-protein coupled receptor 0.0067 0.0338 0.0333
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0147 0.0835 0.1059
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.0338 0.0421
Echinococcus granulosus nmda type glutamate receptor 0.0054 0.026 0.0289
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0078 0.0409 0.051
Loa Loa (eye worm) hypothetical protein 0.0016 0.0025 0.002
Onchocerca volvulus 0.0073 0.0378 0.1188
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0438 0.0609
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0438 0.0491
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0022 0.0199
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0061
Brugia malayi Bromodomain containing protein 0.0077 0.0398 0.0495
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0067 0.0338 0.0333
Mycobacterium ulcerans beta-lactamase 0.0073 0.0378 0.0415
Schistosoma mansoni nAChR subunit 0.0021 0.0053 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.1201 0.7327 1
Plasmodium vivax JmjC domain containing protein 0.0016 0.0024 0.0272
Brugia malayi Trypsin family protein 0.0028 0.0097 0.0109
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0028 0.0097 0.0132
Brugia malayi jmjC domain containing protein 0.0063 0.0315 0.0389
Schistosoma mansoni amine GPCR 0.0067 0.0338 0.0469
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0021 0.0053 0.0057
Onchocerca volvulus 0.0021 0.0053 0.0134
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0509 0.0708
Echinococcus granulosus glutamate receptor 2 0.0054 0.026 0.0289
Echinococcus granulosus serotonin transporter 0.0514 0.3093 0.3496
Entamoeba histolytica kinesin, putative 0.0026 0.0086 0.0102
Brugia malayi CXXC zinc finger family protein 0.0029 0.0104 0.0117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0338 0.0469
Schistosoma mansoni opsin-like receptor 0.0067 0.0338 0.0469
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.0929 0.1051
Schistosoma mansoni glutamate receptor NMDA 0.0054 0.026 0.036
Echinococcus granulosus tyrosine kinase 0.0055 0.0265 0.0295
Onchocerca volvulus 0.0067 0.0338 0.1057
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0021 0.0053 0.0053
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0147 0.0835 0.1059
Brugia malayi Receptor family ligand binding region containing protein 0.0055 0.0265 0.0325
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.0338 0.0333
Brugia malayi Dopamine receptor protein 1 0.128 0.7814 1
Schistosoma mansoni neuropeptide receptor 0.0067 0.0338 0.0469
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0024 0.0068
Onchocerca volvulus Putative nachr subunit 0.0021 0.0053 0.0134
Onchocerca volvulus 0.0067 0.0338 0.1057
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0132
Schistosoma mansoni neuropeptide receptor 0.0067 0.0338 0.0469
Giardia lamblia Kinesin-5 0.0026 0.0086 0.0564
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.183 0.2486
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0031 0.0027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.0338 0.0469
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.4076
Brugia malayi Receptor family ligand binding region containing protein 0.0147 0.0835 0.1055
Entamoeba histolytica hypothetical protein 0.0073 0.0375 0.0497
Onchocerca volvulus 0.0087 0.0464 0.1467
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0021 0.0053 0.0049
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0083 0.0438 0.055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0132
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0194 0.1121 0.6099
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Schistosoma mansoni nAChR subunit 0.0014 0.0013 0.0014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0223 0.027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0015 0.0004
Loa Loa (eye worm) hypothetical protein 0.0047 0.0218 0.0268
Brugia malayi metabotropic glutamate receptor type 2 0.028 0.1654 0.2105
Brugia malayi hypothetical protein 0.0157 0.0892 0.1128
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0378 0.0473
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0067 0.0338 0.0469
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0023 0.0066 0.007
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0021 0.0053 0.0055
Echinococcus multilocularis neuropeptide FF receptor 2 0.0067 0.0338 0.0333
Brugia malayi Kinesin motor domain containing protein 0.0026 0.0086 0.0096
Onchocerca volvulus 0.0067 0.0338 0.1057
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0338 0.0377
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0194 0.1121 0.1263
Mycobacterium tuberculosis Conserved protein 0.0073 0.0378 0.0428
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0087 0.0464 0.0645
Schistosoma mansoni neuropeptide receptor 0.0067 0.0338 0.0469
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0132
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0087 0.0464 0.052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0061 0.0056
Schistosoma mansoni opsin-like receptor 0.0067 0.0338 0.0469
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.007 0.0321
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0054 0.026 0.0289
Echinococcus granulosus nAChR subunit 0.0021 0.0053 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0509 0.0708
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.1121 0.1256
Echinococcus granulosus peptide allatostatin:somatostatin 0.0067 0.0338 0.0377
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0218 0.4093
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0021 0.0053 0.0057
Echinococcus granulosus orexin receptor type 2 0.0067 0.0338 0.0377
Echinococcus multilocularis glutamate receptor 2 0.0054 0.026 0.0255
Brugia malayi hypothetical protein 0.0073 0.0375 0.0466
Loa Loa (eye worm) hypothetical protein 0.0087 0.0464 0.0583
Onchocerca volvulus 0.0054 0.026 0.0804
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0016 0.0022 0.0017
Brugia malayi Trypsin family protein 0.0028 0.0097 0.0109
Toxoplasma gondii exonuclease III APE 0.0022 0.0061 0.0441
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0087 0.0464 0.0579
Loa Loa (eye worm) hypothetical protein 0.0087 0.0464 0.0583
Brugia malayi jmjC domain containing protein 0.0016 0.0024 0.0016
Mycobacterium ulcerans hypothetical protein 0.0047 0.0218 0.0233
Loa Loa (eye worm) hypothetical protein 0.0055 0.0265 0.0328
Echinococcus granulosus zinc finger protein 0.0021 0.0057 0.0059
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0087 0.0464 0.046
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0378 0.7265
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0054 0.026 0.0289
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0021 0.0053 0.0055
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0023 0.0021
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0097 0.0132
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0054 0.026 0.0255
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0021 0.0053 0.0053
Schistosoma mansoni nAChR subunit 0.0021 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0073 0.0378 0.0473
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Schistosoma mansoni nAChR subunit 0.0014 0.0013 0.0014
Schistosoma mansoni growth hormone secretagogue receptor 0.0067 0.0338 0.0469
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0012 0.0013
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0012 0.0013
Onchocerca volvulus 0.0067 0.0338 0.1057
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0223 0.0218
Echinococcus granulosus glutamate receptor 2 0.0054 0.026 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0516 0.0718
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0097 0.0132
Onchocerca volvulus 0.0073 0.0378 0.1188
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0021 0.0053 0.0071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0097 0.0113
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0279 0.0387
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0315 0.0392
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0022 0.0027
Schistosoma mansoni nephrin 0.0013 0.0005 0.0003
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0067 0.0338 0.0418
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0279 0.0311
Schistosoma mansoni neuropeptide receptor 0.0067 0.0338 0.0469
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0087 0.0464 0.4076
Brugia malayi ORL1-like opioid receptor 0.0067 0.0338 0.0418
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0023 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Echinococcus granulosus 7tm_1 domain containing protein 0.0067 0.0338 0.0377
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0277 0.2387
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Schistosoma mansoni hypothetical protein 0.0176 0.1009 0.1408
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0223 0.027
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0218 0.4093
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0218 0.0233
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0021 0.0053 0.0057
Brugia malayi MH2 domain containing protein 0.0123 0.0687 0.0865
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0061 0.0067
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0014 0.0013 0.0005
Plasmodium falciparum kinesin-5 0.0026 0.0086 0.165
Loa Loa (eye worm) hypothetical protein 0.0038 0.0162 0.0197
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.0338 0.0377
Loa Loa (eye worm) trypsin family protein 0.0028 0.0097 0.0113
Loa Loa (eye worm) ACC-1 protein 0.0021 0.0053 0.0057
Brugia malayi hypothetical protein 0.0067 0.0338 0.0418
Loa Loa (eye worm) hypothetical protein 0.0067 0.0338 0.0421
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0023 0.0015
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0057 0.0276 0.5842
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0005
Echinococcus multilocularis sex peptide receptor 0.0067 0.0338 0.0333
Echinococcus granulosus Mastin 0.0028 0.0097 0.0105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0338 0.0333
Onchocerca volvulus 0.0028 0.0097 0.0276
Loa Loa (eye worm) glutamate receptor 0.0337 0.2004 0.2556
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0021 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0067 0.0338 0.0469

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 35 % The compound was tested in vitro for antiproliferative activity against A2058 tumor cell lines ChEMBL. 10508449
Inhibition (functional) = 48 % The compound was tested in vitro for antiproliferative activity against A431 tumor cell lines ChEMBL. 10508449
Inhibition (functional) = 50 % The compound was tested in vitro for antiproliferative activity against HT-29 tumor cell lines ChEMBL. 10508449

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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