Detailed information for compound 1801358

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 309.19 | Formula: C15H14Cl2N2O
  • H donors: 2 H acceptors: 1 LogP: 4.08 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cc(Cl)ccc1Cl)N[C@H](c1ccccc1)C
  • InChi: 1S/C15H14Cl2N2O/c1-10(11-5-3-2-4-6-11)18-15(20)19-14-9-12(16)7-8-13(14)17/h2-10H,1H3,(H2,18,19,20)/t10-/m0/s1
  • InChiKey: NYBTUVJLURHDOE-JTQLQIEISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0069 0.0491 0.0488
Echinococcus multilocularis tubulin alpha chain 0.0927 0.772 0.7718
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.006 0.0051
Loa Loa (eye worm) hypothetical protein 0.0091 0.0679 0.0679
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0036 0.0211 0.0682
Schistosoma mansoni tubulin subunit beta 0.1197 1 1
Schistosoma mansoni tubulin subunit beta 0.1197 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0052 0.0041
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Entamoeba histolytica alpha-amylase family protein 0.0013 0.0024 0.0013
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Trypanosoma brucei alpha tubulin 0.0927 0.772 0.7716
Echinococcus multilocularis aldo keto reductase 0.0201 0.1606 0.1599
Loa Loa (eye worm) hypothetical protein 0.0026 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0305 0.0294
Trichomonas vaginalis aldo/keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0011 0.0003
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0011 0.0003
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Echinococcus granulosus JmjC domain containing protein 4 0.0013 0.0021 0.0013
Echinococcus granulosus Protein kinase C brain isozyme 0.0047 0.0311 0.0302
Leishmania major beta tubulin 0.1197 1 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0555 0.4586 0.4579
Loa Loa (eye worm) jmjC domain-containing protein 0.0051 0.0337 0.0337
Echinococcus granulosus microtubule associated protein 2 0.1177 0.9831 0.9831
Echinococcus granulosus Tubulin alpha 1 chain 0.0927 0.772 0.7718
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0234 0.0757
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0077 0.1817
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.006 0.0056
Schistosoma mansoni atypical protein kinase C 0.0047 0.0311 0.0307
Brugia malayi Cell division protein ftsZ 0.0285 0.2317 0.2317
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1016 0.1006
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1016 0.1006
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0182 0.0161
Trypanosoma brucei beta tubulin 0.1197 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0088 0.0656 0.0636
Onchocerca volvulus 0.0372 0.3046 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0088 0.0656 0.0648
Brugia malayi Protein kinase domain containing protein 0.0047 0.0311 0.0311
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.006 0.006
Echinococcus multilocularis tubulin gamma 1 chain 0.0657 0.5451 0.5448
Trichomonas vaginalis tubulin gamma chain, putative 0.1197 1 1
Loa Loa (eye worm) AUR protein kinase 0.0293 0.2378 0.2378
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0411 0.0408
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0293 0.2378 0.2369
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0182 0.0171
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0068 0.0243
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Mycobacterium ulcerans hypothetical protein 0.0026 0.0133 0.0466
Echinococcus granulosus Tubulin beta 2C chain 0.1197 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0133 0.0133
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0293 0.2378 0.2369
Trypanosoma brucei epsilon tubulin 0.0657 0.5451 0.5442
Brugia malayi phosphoinositide-dependent protein kinase I 0.0055 0.0372 0.0372
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0052 0.0041
Echinococcus multilocularis protein kinase c epsilon type 0.0047 0.0311 0.0302
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0077 0.0069
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0068 0.0483 0.0475
Schistosoma mansoni thyroid hormone receptor 0.0018 0.006 0.0056
Entamoeba histolytica tubulin family protein 0.1197 1 1
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0013 0.0024 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0052 0.0041
Giardia lamblia Alpha-tubulin 0.0927 0.772 0.7703
Brugia malayi Protein kinase domain containing protein 0.0047 0.0311 0.0311
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0133 0.0121
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0133 0.0121
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0049 0.0324 0.0316
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0011 0.0003
Echinococcus multilocularis serine:threonine protein kinase N2 0.0047 0.0311 0.0302
Loa Loa (eye worm) tubulin alpha-3 chain 0.0555 0.4586 0.4586
Loa Loa (eye worm) tubulin alpha chain 0.0927 0.772 0.772
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Brugia malayi tubulin alpha chain - mouse 0.0927 0.772 0.772
Treponema pallidum hypothetical protein 0.0033 0.0185 0.0442
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0021 0.0021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.006 0.0056
Schistosoma mansoni alpha tubulin 0.0927 0.772 0.7719
Loa Loa (eye worm) alpha amylase 0.0013 0.0024 0.0024
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0088 0.0656 0.0645
Echinococcus granulosus mitogen activated protein kinase 0.0047 0.0305 0.0297
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.2378 0.2375
Toxoplasma gondii aurora kinase 0.0293 0.2378 0.2369
Brugia malayi Tubulin beta chain 0.0285 0.2317 0.2317
Echinococcus multilocularis beta tubulin 0.1197 1 1
Brugia malayi tubulin alpha-2 chain 0.0927 0.772 0.772
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Loa Loa (eye worm) intermediate filament protein 0.002 0.0077 0.0077
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0047 0.0305 0.0285
Schistosoma mansoni phd/f-box containing protein 0.0013 0.0021 0.0017
Schistosoma mansoni multidrug resistance protein 0.0012 0.0011 0.0008
Trichomonas vaginalis tubulin beta chain, putative 0.1197 1 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0077
Echinococcus multilocularis chromobox protein 1 0.0064 0.0447 0.0439
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.006 0.006
Trypanosoma cruzi tubulin delta chain 0.0285 0.2317 0.23
Entamoeba histolytica synapsin, putative 0.0139 0.1082 0.1072
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Echinococcus granulosus tubulin alpha chain 0.0927 0.772 0.7718
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0087 0.0075
Trichomonas vaginalis tubulin, putative 0.0372 0.3046 0.3038
Plasmodium vivax delta tubulin, putative 0.0285 0.2317 0.2308
Brugia malayi jmjC domain containing protein 0.0013 0.0021 0.0021
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.006 0.006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0051 0.0337 0.0334
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0358 0.0347
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0068 0.0243
Schistosoma mansoni loxhd1 0.0069 0.0491 0.0488
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0133 0.0466
Brugia malayi Doublecortin family protein 0.0069 0.0491 0.0491
Mycobacterium tuberculosis Probable oxidoreductase 0.0201 0.1606 0.6916
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0077
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0321 0.0321
Echinococcus multilocularis geminin 0.0533 0.4401 0.4396
Brugia malayi Protein kinase domain containing protein 0.0055 0.0372 0.0372
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0038 0.0233 0.0899
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Schistosoma mansoni ABC transporter 0.0017 0.0052 0.0048
Brugia malayi isocitrate dehydrogenase 0.0032 0.0182 0.0182
Echinococcus granulosus Tubulin beta 2C chain 0.1197 1 1
Echinococcus multilocularis alpha glucosidase 0.0013 0.0024 0.0016
Echinococcus granulosus aurora kinase A 0.0293 0.2378 0.2371
Toxoplasma gondii alpha amylase, catalytic domain-containing protein 0.0054 0.037 0.0359
Loa Loa (eye worm) tubulin beta chain 0.0285 0.2317 0.2317
Trypanosoma cruzi aurora B kinase, putative 0.0293 0.2378 0.2361
Trichomonas vaginalis tubulin gamma chain, putative 0.0657 0.5451 0.5446
Schistosoma mansoni hypothetical protein 0.0016 0.0049 0.0045
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.0977 0.0977
Schistosoma mansoni jumonji domain containing protein 0.0049 0.0324 0.032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0052 0.0041
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0059 0.0411 0.1664
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0027 0.0016
Leishmania major beta tubulin 0.1197 1 1
Plasmodium vivax aldehyde reductase, putative 0.0058 0.0402 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0311 0.0307
Mycobacterium tuberculosis Maltooligosyltrehalose trehalohydrolase TreZ 0.0013 0.0024 0.0054
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0201 0.1606 0.1606
Brugia malayi p70 ribosomal S6 kinase beta 0.0131 0.1016 0.1016
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0087 0.0078
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0133 0.0466
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.006 0.0051
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.3272 0.3266
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.006 0.0051
Echinococcus multilocularis serine:threonine protein kinase N2 0.0047 0.0311 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.006 0.006
Trichomonas vaginalis tubulin alpha chain, putative 0.0372 0.3046 0.3038
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0372 0.0361
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0043 0.0271 0.026
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0088 0.0656 0.0636
Echinococcus multilocularis aldo keto reductase 0.0201 0.1606 0.1599
Toxoplasma gondii 1,4-alpha-glucan-branching enzyme 0.0054 0.037 0.0359
Leishmania major epsilon tubulin, putative 0.0657 0.5451 0.5446
Echinococcus granulosus Tubulin alpha 1 chain 0.0927 0.772 0.7718
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0077 0.0065
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Echinococcus granulosus tubulin beta 4A class IVa 0.1197 1 1
Echinococcus multilocularis beta tubulin 0.1197 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0402 0.0391
Loa Loa (eye worm) alpha-tubulin 0.0927 0.772 0.772
Brugia malayi hypothetical protein 0.0069 0.0491 0.0491
Echinococcus granulosus aldo keto reductase 0.0201 0.1606 0.1599
Schistosoma mansoni alpha-amylase 0.0013 0.0024 0.002
Onchocerca volvulus 0.0069 0.0491 0.1603
Echinococcus granulosus tubulin alpha 0.0657 0.5451 0.5448
Trypanosoma brucei alpha tubulin, putative 0.0372 0.3046 0.3031
Trichomonas vaginalis AGC family protein kinase 0.0293 0.2378 0.2369
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0077 0.0069
Onchocerca volvulus 0.0168 0.1323 0.4338
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Toxoplasma gondii beta-1 tubulin, putative 0.1197 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0011 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.006 0.006
Trichomonas vaginalis tubulin alpha chain, putative 0.0372 0.3046 0.3038
Trypanosoma brucei zeta tubulin 0.0285 0.2317 0.23
Toxoplasma gondii glycosyltransferase 0.0054 0.037 0.0359
Mycobacterium leprae cell division protein FtsZ 0.0285 0.2317 1
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.006 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0372 0.0351
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0077
Echinococcus multilocularis protein kinase c iota type 0.0047 0.0311 0.0302
Echinococcus granulosus tubulin gamma 1 chain 0.0657 0.5451 0.5448
Echinococcus multilocularis hypothetical protein 0.0927 0.772 0.7718
Schistosoma mansoni microtubule-associated protein tau 0.1177 0.9831 0.9831
Loa Loa (eye worm) hypothetical protein 0.0036 0.0211 0.0211
Schistosoma mansoni coup transcription factor 0.0018 0.006 0.0056
Entamoeba histolytica alpha-amylase family protein 0.0123 0.0944 0.0933
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Loa Loa (eye worm) ABC transporter 0.0017 0.0052 0.0052
Mycobacterium tuberculosis Conserved protein 0.0058 0.0402 0.1694
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0026 0.0133 0.0133
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0087 0.0066
Echinococcus multilocularis lamin 0.002 0.0077 0.0069
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0182 0.0161
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.006 0.0051
Schistosoma mansoni chromobox protein 0.0064 0.0447 0.0443
Schistosoma mansoni tubulin subunit gamma 0.0657 0.5451 0.545
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Echinococcus granulosus trehalose 6 phosphate hydrolase 0.0013 0.0024 0.0016
Leishmania major beta tubulin 0.1197 1 1
Plasmodium vivax tubulin alpha chain, putative 0.0927 0.772 0.7718
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0182 0.0171
Onchocerca volvulus 0.0201 0.1606 0.5266
Echinococcus granulosus serine threonine protein kinase nrc 0.0088 0.0656 0.0648
Loa Loa (eye worm) hypothetical protein 0.0047 0.0311 0.0311
Brugia malayi Protein kinase domain containing protein 0.0187 0.1487 0.1487
Loa Loa (eye worm) oxidoreductase 0.0201 0.1606 0.1606
Loa Loa (eye worm) hypothetical protein 0.0168 0.1323 0.1323
Echinococcus granulosus tubulin alpha 3 chain 0.0927 0.772 0.7718
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.1487 0.1483
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0311 0.0307
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.006 0.0051
Brugia malayi Tubulin alpha-2 chain 0.0927 0.772 0.772
Giardia lamblia Beta tubulin 0.1197 1 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0201 0.1606 0.1596
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Trypanosoma cruzi tubulin gamma chain 0.0657 0.5451 0.5442
Echinococcus multilocularis muscleblind protein 0.0282 0.2287 0.2281
Toxoplasma gondii AGC kinase 0.0131 0.1016 0.1006
Leishmania major protein kinase, putative 0.0293 0.2378 0.2369
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0133 0.0121
Echinococcus multilocularis tubulin alpha 1C chain 0.0927 0.772 0.7718
Plasmodium falciparum alpha tubulin 2 0.0927 0.772 0.7718
Onchocerca volvulus 0.0028 0.0147 0.047
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.006 0.006
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Trichomonas vaginalis tubulin beta chain, putative 0.0927 0.772 0.7718
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0058 0.0402 0.0391
Mycobacterium tuberculosis Trehalose synthase TreS 0.0013 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0282 0.2287 0.2287
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1016 0.1006
Loa Loa (eye worm) glutaminase 0.029 0.2353 0.2353
Entamoeba histolytica PH domain containing protein kinase, putative 0.0088 0.0656 0.0645
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0011 0.0003
Mycobacterium leprae Possible oxidoreductase 0.0058 0.0402 0.1648
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1197 1 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0133 0.0121
Trichomonas vaginalis aldo/keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus granulosus tubulin alpha chain 0.0927 0.772 0.7718
Trichomonas vaginalis starch branching enzyme II, putative 0.0054 0.037 0.0359
Echinococcus multilocularis Tubulin beta 2C chain 0.1197 1 1
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1016 0.1006
Echinococcus multilocularis tubulin alpha chain 0.0927 0.772 0.7718
Echinococcus granulosus aldo keto reductase 0.0201 0.1606 0.1599
Echinococcus granulosus voltage gated potassium channel subunit 0.0058 0.0402 0.0394
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.006 0.0051
Trypanosoma brucei PAB1-binding protein , putative 0.0055 0.0372 0.0351
Schistosoma mansoni hypothetical protein 0.0049 0.0321 0.0317
Trichomonas vaginalis AGC family protein kinase 0.0047 0.0311 0.0299
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0038 0.0233 0.0899
Loa Loa (eye worm) oxidoreductase 0.0201 0.1606 0.1606
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0052 0.0041
Trichomonas vaginalis amylase, putative 0.0054 0.037 0.0359
Loa Loa (eye worm) tubulin alpha chain 0.0927 0.772 0.772
Echinococcus multilocularis nervana 2 0.0084 0.0617 0.0609
Toxoplasma gondii aldose reductase, putative 0.0201 0.1606 0.1596
Echinococcus granulosus Tubulin alpha 1 chain 0.0927 0.772 0.7718
Trichomonas vaginalis tubulin beta chain, putative 0.0927 0.772 0.7718
Schistosoma mansoni transcription factor LCR-F1 0.0068 0.0483 0.048
Trichomonas vaginalis xanthine dehydrogenase, putative 0.02 0.1599 0.159
Schistosoma mansoni alpha-amylase 0.0013 0.0024 0.002
Trypanosoma brucei aldo/keto reductase, putative 0.0058 0.0402 0.0382
Giardia lamblia Aldose reductase 0.0201 0.1606 0.1543
Toxoplasma gondii aldo-keto reductase 0.0058 0.0402 0.0391
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Trichomonas vaginalis tubulin gamma chain, putative 0.0657 0.5451 0.5446
Schistosoma mansoni multidrug resistance protein 0.0012 0.0011 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0211 0.02
Trichomonas vaginalis chromobox protein, putative 0.0064 0.0447 0.0436
Schistosoma mansoni hypothetical protein 0.0049 0.0321 0.0317
Brugia malayi intermediate filament protein 0.002 0.0077 0.0077
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0049 0.0324 0.0316
Onchocerca volvulus 0.002 0.0077 0.0241
Giardia lamblia Kinase, CMGC MAPK 0.0047 0.0305 0.0233
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0068 0.0483 0.0472
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Loa Loa (eye worm) oxidoreductase 0.0201 0.1606 0.1606
Plasmodium vivax tubulin epsilon chain, putative 0.0657 0.5451 0.5446
Loa Loa (eye worm) hypothetical protein 0.0095 0.071 0.071
Schistosoma mansoni tubulin subunit alpha 0.0285 0.2317 0.2314
Entamoeba histolytica alpha-amylase family protein 0.0123 0.0944 0.0933
Echinococcus granulosus chromobox protein 1 0.0064 0.0447 0.0439
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0293 0.2378 0.2369
Brugia malayi 1,4-alpha-glucan branching enzyme 0.0054 0.037 0.037
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0068 0.0481 0.1963
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0011 0.0003
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0084 0.0617 0.0609
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0058 0.0402 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0311 0.0307
Plasmodium falciparum LCCL domain-containing protein 0.0069 0.0491 0.048
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0182 0.0174
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0285 0.2317 0.2308
Brugia malayi MH2 domain containing protein 0.0127 0.0977 0.0977
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0187 0.1487 0.1487
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0047 0.0311 0.0311
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0012 0.0012
Schistosoma mansoni thyroid hormone receptor 0.0018 0.006 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.006 0.006
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0118 0.0109
Trichomonas vaginalis tubulin beta chain, putative 0.0372 0.3046 0.3038
Entamoeba histolytica tubulin family protein 0.1197 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0058 0.0402 0.0391
Trypanosoma brucei RNA helicase, putative 0.0237 0.1912 0.1895
Onchocerca volvulus 0.002 0.0077 0.0241
Onchocerca volvulus 0.0069 0.0491 0.1603
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0087 0.0075
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.006 0.0051
Echinococcus granulosus tubulin delta chain 0.0285 0.2317 0.231
Echinococcus multilocularis trehalose 6 phosphate hydrolase 0.0013 0.0024 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.006 0.006
Entamoeba histolytica oligo-1,6-glucosidase, putative 0.0013 0.0024 0.0013
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.002 0.0077 0.0074
Echinococcus granulosus Tubulin beta 2C chain 0.1197 1 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0051 0.0337 0.0334
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0641 0.5315 0.5309
Trichomonas vaginalis alpha-amylase, putative 0.0109 0.0831 0.082
Brugia malayi ABC transporter family protein 0.0012 0.0011 0.0011
Schistosoma mansoni alpha-amylase 0.0013 0.0024 0.002
Entamoeba histolytica protein kinase , putative 0.0293 0.2378 0.2369
Plasmodium falciparum tubulin delta chain, putative 0.0285 0.2317 0.2308
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0094 0.0707 0.2933
Loa Loa (eye worm) hypothetical protein 0.0054 0.037 0.037
Echinococcus multilocularis jumonji domain containing 1A 0.0013 0.0021 0.0013
Trypanosoma cruzi epsilon tubulin, putative 0.0657 0.5451 0.5442
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.006 0.006
Onchocerca volvulus 0.0201 0.1606 0.5266
Entamoeba histolytica ABC transporter, putative 0.002 0.0077 0.0066
Loa Loa (eye worm) tubulin beta-2A chain 0.1197 1 1
Schistosoma mansoni serine/threonine-protein kinase 0.0088 0.0656 0.0653
Loa Loa (eye worm) BEN-1 protein 0.1197 1 1
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0077 0.0069
Chlamydia trachomatis glycogen hydrolase 0.0013 0.0024 0.0349
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0088 0.0656 0.0645
Loa Loa (eye worm) AUR protein kinase 0.0293 0.2378 0.2378
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0011 0.0003
Loa Loa (eye worm) AGC/AKT protein kinase 0.0131 0.1016 0.1016
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Leishmania major hypothetical protein, conserved 0.0055 0.0372 0.0361
Trichomonas vaginalis amylase, putative 0.0123 0.0944 0.0933
Brugia malayi chromobox protein homolog 3 0.0036 0.0211 0.0211
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.006 0.0056
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.006 0.006
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0087 0.0075
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0011
Plasmodium vivax multidomain scavenger receptor, putative 0.0069 0.0491 0.048
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0077 0.0069
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0011 0.0003
Echinococcus multilocularis Tubulin beta 2C chain 0.1197 1 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0087 0.0075
Trichomonas vaginalis alpha-amylase, putative 0.0123 0.0944 0.0933
Trichomonas vaginalis AGC family protein kinase 0.0293 0.2378 0.2369
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0047 0.0305 0.0294
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0058 0.0402 0.0402
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0011 0.0003
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0088 0.0656 0.0648
Loa Loa (eye worm) hypothetical protein 0.0055 0.0372 0.0372
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0077 0.0069
Echinococcus multilocularis chromobox protein 1 0.0064 0.0447 0.0439
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0234 0.0223
Schistosoma mansoni protein phosphatase 2C 0.0013 0.0021 0.0017
Schistosoma mansoni tubulin subunit delta 0.0285 0.2317 0.2314
Giardia lamblia Alpha-tubulin 0.0927 0.772 0.7703
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0077 0.0065
Loa Loa (eye worm) tubulin alpha 2 0.0641 0.5315 0.5315
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0182 0.0739
Schistosoma mansoni alpha tubulin 0.0927 0.772 0.7719
Brugia malayi serine/threonine protein kinase 6 0.0293 0.2378 0.2378
Trypanosoma cruzi aldo-keto reductase 0.0201 0.1606 0.1588
Onchocerca volvulus 0.0026 0.0133 0.0423
Echinococcus granulosus FTZ F1 alpha 0.0018 0.006 0.0051
Trypanosoma brucei zeta tubulin, putative 0.0285 0.2317 0.23
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0124 0.0112
Leishmania major beta tubulin 0.1197 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0058 0.0402 0.0391
Echinococcus granulosus tubulin alpha chain 0.0927 0.772 0.7718
Echinococcus multilocularis peroxisome assembly protein 26 0.0927 0.772 0.7718
Brugia malayi jmjC domain containing protein 0.0049 0.0324 0.0324
Brugia malayi hypothetical protein 0.0055 0.0372 0.0372
Loa Loa (eye worm) multidrug resistance protein 3 0.0012 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0024 0.0013
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.006 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.006 0.006
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.006 0.0051
Echinococcus granulosus chromobox protein 1 0.0064 0.0447 0.0439
Echinococcus granulosus tubulin alpha 1C chain 0.0927 0.772 0.7718
Schistosoma mansoni alpha tubulin 0.0927 0.772 0.7719
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0058 0.0402 0.0394
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.074 0.6148 0.6145
Leishmania major beta tubulin 0.1197 1 1
Loa Loa (eye worm) glutaminase 2 0.029 0.2353 0.2353
Trichomonas vaginalis tubulin alpha chain, putative 0.0372 0.3046 0.3038
Schistosoma mansoni chromobox protein 0.0064 0.0447 0.0443
Trichomonas vaginalis tubulin gamma chain, putative 0.0285 0.2317 0.2308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0052 0.0041
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0011 0.0003
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Plasmodium vivax tubulin alpha chain, putative 0.0927 0.772 0.7718
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.006 0.0051
Echinococcus multilocularis glucan (1,4 alpha), branching enzyme 1 0.0054 0.037 0.0362
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Schistosoma mansoni tubulin subunit alpha 0.0927 0.772 0.7719
Brugia malayi jmjC domain containing protein 0.0013 0.0021 0.0021
Plasmodium falciparum aldo-keto reductase, putative 0.0058 0.0402 0.0391
Echinococcus granulosus beta tubulin 0.1197 1 1
Leishmania major beta tubulin 0.1197 1 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0305 0.0285
Entamoeba histolytica protein kinase, putative 0.0131 0.1016 0.1006
Onchocerca volvulus 0.0201 0.1606 0.5266
Echinococcus multilocularis cpg binding protein 0.003 0.016 0.0152
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Loa Loa (eye worm) hypothetical protein 0.0028 0.0147 0.0147
Entamoeba histolytica protein kinase, putative 0.0131 0.1016 0.1006
Schistosoma mansoni tubulin subunit beta 0.1197 1 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0047 0.0305 0.0305
Brugia malayi CHD4 protein 0.0012 0.0012 0.0012
Echinococcus multilocularis tubulin delta chain 0.0285 0.2317 0.231
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0321 0.0321
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0011 0.0003
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0068 0.0481 0.1963
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0012 0.0004
Schistosoma mansoni cpg binding protein 0.0028 0.0147 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0311 0.0307
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0087 0.0075
Mycobacterium tuberculosis Maltooligosyltrehalose synthase TreY 0.0013 0.0024 0.0054
Echinococcus multilocularis voltage gated potassium channel subunit 0.0058 0.0402 0.0394
Mycobacterium ulcerans oxidoreductase 0.0201 0.1606 0.6792
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0133 0.0466
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.006 0.0056
Entamoeba histolytica hypothetical protein 0.0068 0.0483 0.0472
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0131 0.1016 0.1016
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0311 0.0307
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0047 0.0311 0.0302
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0068 0.0243
Schistosoma mansoni ap endonuclease 0.0021 0.0087 0.0083
Giardia lamblia Aldose reductase 0.0201 0.1606 0.1543
Echinococcus multilocularis nervana 2 0.0084 0.0617 0.0609
Giardia lamblia Gamma tubulin 0.0657 0.5451 0.5417
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0182 0.0174
Loa Loa (eye worm) hypothetical protein 0.0154 0.1206 0.1206
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0201 0.1606 0.1596
Trypanosoma cruzi ATP-binding cassette protein, putative 0.002 0.0077 0.0056
Echinococcus multilocularis mitogen activated protein kinase 3 0.0047 0.0305 0.0297
Brugia malayi jmjC domain containing protein 0.0013 0.0021 0.0021
Trichomonas vaginalis tubulin alpha chain, putative 0.1197 1 1
Brugia malayi Muscleblind-like protein 0.0282 0.2287 0.2287
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0021 0.0021
Entamoeba histolytica protein kinase, putative 0.0131 0.1016 0.1006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0069 0.0491 0.0483
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0077 0.0226
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1016 0.1006
Trypanosoma brucei epsilon tubulin 0.0657 0.5451 0.5442
Entamoeba histolytica aldose reductase, putative 0.0201 0.1606 0.1596
Echinococcus granulosus intermediate filament protein 0.002 0.0077 0.0069
Trypanosoma brucei beta tubulin 0.1197 1 1
Trichomonas vaginalis amylase, putative 0.0123 0.0944 0.0933
Brugia malayi Tubulin gamma chain 0.0657 0.5451 0.5451
Plasmodium falciparum tubulin beta chain 0.1197 1 1
Schistosoma mansoni multidrug resistance protein 0.0012 0.0011 0.0008
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0077 0.0282
Echinococcus multilocularis Tubulin beta 2C chain 0.1197 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0124 0.0112
Loa Loa (eye worm) alpha-tubulin 0.0927 0.772 0.772
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0013 0.0021 0.0017
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0187 0.1487 0.1479
Mycobacterium ulcerans hypothetical protein 0.0033 0.0185 0.0693
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus multilocularis tubulin alpha chain 0.0927 0.772 0.7718
Schistosoma mansoni lamin 0.002 0.0077 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.006 0.006
Schistosoma mansoni ap endonuclease 0.0021 0.0087 0.0083
Schistosoma mansoni hypothetical protein 0.0105 0.0796 0.0792
Echinococcus granulosus beta tubulin 0.1197 1 1
Brugia malayi multidrug resistance protein 3 0.0012 0.0011 0.0011
Echinococcus granulosus tubulin alpha 3 chain 0.0927 0.772 0.7718
Trichomonas vaginalis AGC family protein kinase 0.0047 0.0311 0.0299
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.1206 0.1206
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Trypanosoma brucei prostaglandin f synthase 0.0201 0.1606 0.1588
Echinococcus granulosus cpg binding protein 0.003 0.016 0.0152
Echinococcus multilocularis RUN 0.0069 0.0491 0.0483
Leishmania major beta tubulin 0.1197 1 1
Trypanosoma brucei alpha tubulin 0.0927 0.772 0.7716
Echinococcus multilocularis mitogen activated protein kinase 0.0047 0.0305 0.0297
Leishmania major beta tubulin 0.1197 1 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0321 0.0321
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.0035 0.0026
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0058 0.0402 0.0402
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0133 0.0133
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.006 0.0056
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0011 0.0003
Trichomonas vaginalis tubulin, putative 0.0372 0.3046 0.3038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.1206 0.1206
Echinococcus multilocularis aldehyde reductase 0.0143 0.1115 0.1107
Echinococcus multilocularis tubulin alpha 3 chain 0.0927 0.772 0.7718
Treponema pallidum hypothetical protein 0.0027 0.0137 0.0225
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0077 0.0229
Echinococcus granulosus lipoxygenase domain containing protein 0.0069 0.0491 0.0483
Trypanosoma cruzi alpha tubulin, putative 0.0927 0.772 0.7716
Echinococcus granulosus phd:f box containing protein 0.0013 0.0021 0.0013
Mycobacterium ulcerans glutaminase 0.029 0.2353 1
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0187 0.1487 0.1487
Trichomonas vaginalis AGC family protein kinase 0.0047 0.0311 0.0299
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Echinococcus granulosus tubulin alpha chain 0.0927 0.772 0.7718
Trichomonas vaginalis tubulin epsilon chain, putative 0.1197 1 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0077
Echinococcus granulosus tubulin beta 1 chain 0.1197 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0087 0.0078
Trichomonas vaginalis alpha-amylase, putative 0.0123 0.0944 0.0933
Mycobacterium ulcerans cell division protein FtsZ 0.0285 0.2317 0.9845
Entamoeba histolytica beta/alpha-amylase precursor, putative 0.0013 0.0024 0.0013
Trichomonas vaginalis alpha-amylase, putative 0.0123 0.0944 0.0933
Entamoeba histolytica protein kinase, putative 0.0293 0.2378 0.2369
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0087 0.027
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0201 0.1606 0.1606
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Plasmodium falciparum alpha tubulin 1 0.0927 0.772 0.7718
Loa Loa (eye worm) hypothetical protein 0.0927 0.772 0.772
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.006 0.0051
Brugia malayi hypothetical protein 0.0168 0.1323 0.1323
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0201 0.1606 0.1596
Trichomonas vaginalis aldehyde oxidase, putative 0.02 0.1599 0.159
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.006 0.0051
Schistosoma mansoni tubulin subunit beta 0.1197 1 1
Leishmania major delta tubulin, putative 0.0285 0.2317 0.2308
Schistosoma mansoni synapsin 0.0139 0.1082 0.1079
Entamoeba histolytica hypothetical protein 0.0068 0.0483 0.0472
Schistosoma mansoni hypothetical protein 0.0025 0.0118 0.0114
Loa Loa (eye worm) hypothetical protein 0.0555 0.4586 0.4586
Schistosoma mansoni alpha-amylase 0.0013 0.0024 0.002
Toxoplasma gondii beta tubulin 0.1197 1 1
Loa Loa (eye worm) tubulin alpha 2 0.0269 0.218 0.218
Onchocerca volvulus 0.0201 0.1606 0.5266
Mycobacterium leprae Conserved hypothetical protein 0.0143 0.1115 0.4758
Brugia malayi Tubulin alpha chain 0.0927 0.772 0.772
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0047 0.0305 0.0285
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0054 0.037 0.0359
Mycobacterium ulcerans hypothetical protein 0.0058 0.0402 0.1623
Entamoeba histolytica tubulin alpha chain, putative 0.0927 0.772 0.7718
Trichomonas vaginalis tubulin beta chain, putative 0.0927 0.772 0.7718
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0796 0.0796
Onchocerca volvulus 0.0018 0.006 0.0184
Loa Loa (eye worm) tubulin beta-4 chain 0.1197 1 1
Entamoeba histolytica alpha-amylase family protein 0.0013 0.0024 0.0013
Schistosoma mansoni cpg binding protein 0.003 0.016 0.0157
Giardia lamblia Beta tubulin 0.1197 1 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.0035 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Onchocerca volvulus 0.0058 0.0402 0.1308
Brugia malayi nuclear receptor NHR-88 0.0018 0.006 0.006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0052 0.0041
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Echinococcus multilocularis tubulin alpha 3 chain 0.0927 0.772 0.7718
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0201 0.1606 0.1606
Loa Loa (eye worm) hypothetical protein 0.0019 0.0074 0.0074
Leishmania major hypothetical protein, conserved 0.0013 0.0021 0.001
Trypanosoma brucei ATP-binding cassette protein, putative 0.002 0.0077 0.0056
Loa Loa (eye worm) doublecortin family protein 0.0069 0.0491 0.0491
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0187 0.1487 0.4874
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0133 0.0133
Leishmania major beta tubulin 0.1197 1 1
Plasmodium falciparum ABC transporter G family member 2 0.002 0.0077 0.0066
Trypanosoma brucei ABC transporter, putative 0.002 0.0077 0.0056
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.006 0.0051
Brugia malayi SET domain containing protein 0.0011 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0285 0.2317 1
Brugia malayi jmjC domain containing protein 0.0013 0.0021 0.0021
Entamoeba histolytica tubulin gamma chain 0.0657 0.5451 0.5446
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0321 0.0321
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0058 0.0402 0.0391
Schistosoma mansoni hypothetical protein 0.0399 0.3272 0.3269
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0047 0.0311 0.0302
Echinococcus multilocularis synapsin 0.0139 0.1082 0.1074
Mycobacterium tuberculosis Cell division protein FtsZ 0.0285 0.2317 1
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0211 0.02
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0058 0.0402 0.0391
Brugia malayi CXXC zinc finger family protein 0.0028 0.0147 0.0147
Trichomonas vaginalis tubulin epsilon chain, putative 0.0927 0.772 0.7718
Entamoeba histolytica alcohol dehydrogenase, putative 0.0058 0.0402 0.0391
Trypanosoma cruzi Protein kinase B 0.0088 0.0656 0.0636
Schistosoma mansoni alpha-amylase 0.0013 0.0024 0.002
Schistosoma mansoni hypothetical protein 0.0533 0.4401 0.4398
Schistosoma mansoni hypothetical protein 0.0049 0.0321 0.0317
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1016 0.1006
Schistosoma mansoni serine/threonine kinase 0.0047 0.0311 0.0307
Trypanosoma brucei beta tubulin 0.1197 1 1
Treponema pallidum quinoline 2-oxidoreductase 0.0032 0.0179 0.0414
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0047 0.0305 0.0285
Loa Loa (eye worm) alpha amylase 0.0013 0.0024 0.0024
Loa Loa (eye worm) BEN-1 protein 0.1197 1 1
Schistosoma mansoni hypothetical protein 0.0013 0.0024 0.002
Schistosoma mansoni tubulin subunit alpha 0.0927 0.772 0.7719
Brugia malayi MAP kinase sur-1 0.0047 0.0305 0.0305
Trypanosoma cruzi aldo/keto reductase, putative 0.0201 0.1606 0.1588
Schistosoma mansoni protein kinase 0.0293 0.2378 0.2375
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.006 0.0051
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0094 0.0707 0.3017
Entamoeba histolytica protein kinase, putative 0.0293 0.2378 0.2369
Echinococcus multilocularis lipoxygenase domain containing protein 0.0069 0.0491 0.0483
Trichomonas vaginalis glutaminase, putative 0.029 0.2353 0.2344
Echinococcus multilocularis serine threonine protein kinase 0.0047 0.0311 0.0302
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus granulosus tubulin subunit TubB 0.0927 0.772 0.7718
Toxoplasma gondii alpha tubulin TUBA1 0.0927 0.772 0.7718
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0011 0.0003
Brugia malayi Protein kinase domain containing protein 0.0131 0.1016 0.1016
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0047 0.0305 0.0294
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Trypanosoma brucei aurora B kinase 0.0293 0.2378 0.2361
Onchocerca volvulus 0.0012 0.0011 0.0025
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0038 0.0233 0.0962
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0087 0.0013
Leishmania major beta tubulin 0.1197 1 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0147 0.0147
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0133 0.0466
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0201 0.1606 0.1599
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0305 0.0294
Echinococcus multilocularis rac serine:threonine kinase 0.0088 0.0656 0.0648
Toxoplasma gondii Alpha-amylase AMY3, putative 0.0013 0.0024 0.0013
Onchocerca volvulus 0.0201 0.1606 0.5266
Plasmodium falciparum tubulin gamma chain 0.0657 0.5451 0.5446
Entamoeba histolytica alcohol dehydrogenase, putative 0.0058 0.0402 0.0391
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0305 0.0285
Giardia lamblia Delta tubulin 0.0285 0.2317 0.2259
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0182 0.0174
Echinococcus multilocularis Tubulin alpha 1 chain 0.0927 0.772 0.7718
Mycobacterium ulcerans glycogen branching protein 0.0054 0.037 0.1485
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0055 0.0372 0.0372
Loa Loa (eye worm) oxidoreductase 0.0201 0.1606 0.1606
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0372 0.0361
Trypanosoma cruzi beta tubulin, putative 0.1197 1 1
Onchocerca volvulus Bile acid receptor homolog 0.0018 0.006 0.0184
Giardia lamblia 1,4-alpha-glucan branching enzyme 0.0054 0.037 0.0298
Brugia malayi Tubulin alpha-2 chain 0.0927 0.772 0.772
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0311 0.0307
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0133 0.0121
Echinococcus multilocularis tubulin alpha chain 0.0927 0.772 0.7718
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0012 0.0011 0.0011
Plasmodium falciparum serine/threonine protein kinase, putative 0.0293 0.2378 0.2369
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0047 0.0311 0.0311
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0182 0.0178
Brugia malayi jmjC domain containing protein 0.0051 0.0337 0.0337
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0021 0.0021
Trichomonas vaginalis tubulin beta chain, putative 0.0927 0.772 0.7718
Echinococcus granulosus protein kinase c iota type 0.0047 0.0311 0.0302
Brugia malayi ABC transporter family protein 0.0017 0.0052 0.0052
Mycobacterium tuberculosis Probable glucanase GlgE 0.0013 0.0024 0.0054
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0182 0.0182
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0182 0.0161
Leishmania major beta tubulin 0.1197 1 1
Schistosoma mansoni cpg binding protein 0.003 0.016 0.0157
Loa Loa (eye worm) beta-tubulin 0.1197 1 1
Echinococcus granulosus RUN 0.0069 0.0491 0.0483
Leishmania major aldo-keto reductase-like protein 0.0201 0.1606 0.1596
Echinococcus multilocularis Polycystic kidney disease protein 0.0069 0.0491 0.0483
Trichomonas vaginalis tubulin beta chain, putative 0.0927 0.772 0.7718
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0087 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.006 0.006
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0321 0.0312
Echinococcus multilocularis serine:threonine protein kinase 38 0.0047 0.0311 0.0302
Plasmodium vivax tubulin beta chain, putative 0.1197 1 1
Onchocerca volvulus 0.0028 0.0147 0.0469
Echinococcus granulosus aldehyde reductase 0.0143 0.1115 0.1107
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0068 0.0483 0.0475
Schistosoma mansoni starch branching enzyme II 0.0054 0.037 0.0366
Trypanosoma cruzi ABC transporter, putative 0.002 0.0077 0.0056
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0077 0.0069
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0047 0.0311 0.0311
Entamoeba histolytica aldose reductase, putative 0.0201 0.1606 0.1596
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.002 0.0077 0.0066
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0068 0.0243
Schistosoma mansoni nuclear hormone receptor 0.0018 0.006 0.0056
Echinococcus multilocularis lysine specific demethylase 5A 0.0049 0.0324 0.0316
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0285 0.2317 0.2308
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0133 0.0121
Trichomonas vaginalis aldo-keto reductase, putative 0.0058 0.0402 0.0391
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0201 0.1606 0.6899
Treponema pallidum cell division protein FtsZ 0.0285 0.2317 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0372 0.0361
Trichomonas vaginalis tubulin epsilon chain, putative 0.0285 0.2317 0.2308
Plasmodium vivax ABC transporter G family member 2, putative 0.002 0.0077 0.0066
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0018 0.006 0.0184
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0133 0.0525
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.006 0.006
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0068 0.0481 0.2037
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0077 0.0229
Trichomonas vaginalis AGC family protein kinase 0.0131 0.1016 0.1006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.006 0.006
Leishmania major prostaglandin f synthase, putative 0.0201 0.1606 0.1596
Trypanosoma brucei alpha tubulin 0.0927 0.772 0.7716
Giardia lamblia Beta tubulin 0.1197 1 1
Echinococcus multilocularis Glutaredoxin protein 5 0.0084 0.0617 0.0609
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0011 0.0003
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0055 0.0372 0.0364
Brugia malayi hypothetical protein 0.0069 0.0491 0.0491
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.002 0.0077 0.0066
Trypanosoma brucei tubulin gamma chain 0.0657 0.5451 0.5442
Leishmania major beta tubulin 0.1197 1 1
Trichomonas vaginalis tubulin beta chain, putative 0.0927 0.772 0.7718
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Echinococcus multilocularis aurora kinase A 0.0293 0.2378 0.2371
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.1206 0.1206
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0133 0.0474
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0013 0.0024 0.0024
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0305 0.0294
Loa Loa (eye worm) hypothetical protein 0.0282 0.2287 0.2287
Trichomonas vaginalis tubulin, putative 0.1197 1 1
Schistosoma mansoni rab6-interacting 0.0069 0.0491 0.0488
Giardia lamblia Aurora kinase 0.0293 0.2378 0.2321
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0293 0.2378 0.2371
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0077 0.0229
Entamoeba histolytica tubulin alpha-1 chain 0.0927 0.772 0.7718
Plasmodium vivax ataxin-2 like protein, putative 0.0055 0.0372 0.0361
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0321 0.0312
Toxoplasma gondii beta-tubulin, putative 0.1197 1 1
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0372 0.0361
Leishmania major beta tubulin 0.1197 1 1
Schistosoma mansoni lamin 0.002 0.0077 0.0073
Echinococcus multilocularis tubulin alpha 0.0657 0.5451 0.5448
Echinococcus multilocularis tubulin subunit TubB 0.0927 0.772 0.7718
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0372 0.0351
Plasmodium falciparum JmjC domain-containing protein, putative 0.0013 0.0021 0.001
Schistosoma mansoni jumonji domain containing protein 0.0013 0.0021 0.0017
Schistosoma mansoni pol-related 0.0201 0.1606 0.1602
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.006 0.006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0182 0.0174
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0182 0.0174
Entamoeba histolytica protein kinase domain containing protein 0.0293 0.2378 0.2369
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0027 0.0016
Entamoeba histolytica protein kinase 2, putative 0.0088 0.0656 0.0645
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0077
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0077 0.0077
Echinococcus granulosus mitogen activated protein kinase 3 0.0047 0.0305 0.0297
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.006 0.006
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0054 0.037 0.0359
Echinococcus multilocularis Tubulin beta 2C chain 0.1197 1 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0182 0.0174
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0049 0.0321 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0372 0.0368
Loa Loa (eye worm) AUR protein kinase 0.0293 0.2378 0.2378
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0321 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.006 0.006
Echinococcus granulosus alpha glucosidase 0.0013 0.0024 0.0016
Entamoeba histolytica alpha-amylase, putative 0.0013 0.0024 0.0013
Mycobacterium tuberculosis 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) 0.0054 0.037 0.1554
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0182 0.0171
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.006 0.006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0087 0.0066
Brugia malayi hypothetical protein 0.0035 0.0208 0.0208
Loa Loa (eye worm) tubulin beta chain 0.1197 1 1
Loa Loa (eye worm) hypothetical protein 0.0641 0.5315 0.5315
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0412 0.3383 0.3377
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0201 0.1606 0.1599
Echinococcus granulosus Glutaredoxin protein 5 0.0084 0.0617 0.0609
Echinococcus multilocularis Tubulin beta 2C chain 0.1197 1 1
Brugia malayi hypothetical protein 0.0068 0.0483 0.0483
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.006 0.006
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0412 0.3383 0.3377
Loa Loa (eye worm) heterochromatin protein 1 0.0064 0.0447 0.0447
Schistosoma mansoni phosphatidylserine receptor 0.0013 0.0021 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0133 0.0525
Leishmania major gamma-tubulin 0.0657 0.5451 0.5446
Echinococcus granulosus geminin 0.0533 0.4401 0.4396
Brugia malayi Hr1 repeat family protein 0.0047 0.0311 0.0311
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.002 0.0077 0.0066
Echinococcus multilocularis tubulin beta 1 chain 0.1197 1 1
Echinococcus granulosus lamin 0.002 0.0077 0.0069
Trypanosoma brucei tubulin delta chain 0.0285 0.2317 0.23
Echinococcus granulosus Tubulin beta 2C chain 0.1197 1 1
Echinococcus granulosus serine:threonine protein kinase N2 0.0047 0.0311 0.0302
Echinococcus multilocularis tubulin subunit beta 0.1197 1 1
Leishmania major beta tubulin 0.1197 1 1
Schistosoma mansoni tubulin subunit beta 0.1197 1 1
Echinococcus multilocularis tubulin epsilon chain 0.0657 0.5451 0.5448
Schistosoma mansoni rab6-interacting 0.0069 0.0491 0.0488
Schistosoma mansoni polycystin 1-related 0.0069 0.0491 0.0488
Trypanosoma cruzi zeta tubulin, putative 0.0285 0.2317 0.23
Trypanosoma cruzi tubulin delta chain 0.0285 0.2317 0.23
Echinococcus multilocularis aldo keto reductase 0.0201 0.1606 0.1599
Trypanosoma brucei alpha tubulin 0.0927 0.772 0.7716
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0182 0.0171
Brugia malayi steroid hormone receptor 0.0018 0.006 0.006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.006 0.006
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Entamoeba histolytica hypothetical protein 0.0013 0.0024 0.0013
Loa Loa (eye worm) AGC/PKN protein kinase 0.0047 0.0311 0.0311
Echinococcus multilocularis musashi 0.002 0.0077 0.0069
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.0977 0.0977
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0087 0.0066
Echinococcus multilocularis Tubulin alpha 1 chain 0.0927 0.772 0.7718
Trypanosoma brucei beta tubulin 0.1197 1 1
Echinococcus multilocularis lamin dm0 0.002 0.0077 0.0069
Echinococcus granulosus lysine specific demethylase 6a 0.0013 0.0021 0.0013
Trichomonas vaginalis tubulin alpha chain, putative 0.0657 0.5451 0.5446
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0182 0.0161
Echinococcus granulosus NDR protein kinase 0.0047 0.0311 0.0302
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0182 0.0182
Trichomonas vaginalis chromobox protein, putative 0.0064 0.0447 0.0436
Entamoeba histolytica hypothetical protein 0.0068 0.0483 0.0472
Loa Loa (eye worm) tubulin alpha-2 chain 0.0927 0.772 0.772
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.006 0.006
Onchocerca volvulus Protein ultraspiracle homolog 0.0018 0.006 0.0184
Plasmodium vivax JmjC domain containing protein 0.0013 0.0021 0.001
Echinococcus granulosus protein kinase c epsilon type 0.0047 0.0311 0.0302
Trypanosoma cruzi zeta tubulin, putative 0.0285 0.2317 0.23
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0077
Trypanosoma brucei rac serine-threonine kinase, putative 0.0131 0.1016 0.0997
Echinococcus multilocularis aldo keto reductase 0.0201 0.1606 0.1599
Echinococcus multilocularis muscleblind protein 1 0.0282 0.2287 0.2281
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0012 0.0004
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0293 0.2378 0.2371
Loa Loa (eye worm) hypothetical protein 0.0105 0.0796 0.0796
Echinococcus multilocularis microtubule associated protein 2 0.1177 0.9831 0.9831
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0118 0.0109
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0657 0.5451 0.5446
Echinococcus granulosus nervana 2 0.0084 0.0617 0.0609
Plasmodium falciparum tubulin epsilon chain, putative 0.0657 0.5451 0.5446
Echinococcus granulosus lysine specific demethylase 5A 0.0051 0.0337 0.0329
Schistosoma mansoni potassium channel beta 0.0058 0.0402 0.0398
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0047 0.0311 0.0302
Echinococcus granulosus peroxisome assembly protein 26 0.0927 0.772 0.7718
Schistosoma mansoni tubulin subunit beta 0.1197 1 1
Echinococcus granulosus alpha tubulin 0.0927 0.772 0.7718
Loa Loa (eye worm) tubulin alpha 2 0.0641 0.5315 0.5315
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0094 0.0707 0.2933
Echinococcus granulosus synapsin 0.0139 0.1082 0.1074
Echinococcus granulosus lipoxygenase domain containing protein 0.0069 0.0491 0.0483
Echinococcus granulosus tubulin epsilon chain 0.0657 0.5451 0.5448
Entamoeba histolytica PH domain containing protein kinase, putative 0.0088 0.0656 0.0645
Brugia malayi glutaminase DH11.1 0.029 0.2353 0.2353
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0305 0.0294
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0058 0.0402 0.0391
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0047 0.0311 0.0311
Schistosoma mansoni aldo-keto reductase 0.0201 0.1606 0.1602
Trichomonas vaginalis conserved hypothetical protein 0.0285 0.2317 0.2308
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0087 0.0327
Schistosoma mansoni glutaminase 0.029 0.2353 0.235
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0133 0.1029 0.4317
Echinococcus granulosus serine/threonine protein kinase 0.0088 0.0656 0.0648
Trypanosoma cruzi epsilon tubulin, putative 0.0657 0.5451 0.5442
Brugia malayi serine/threonine-protein kinase 6 0.0293 0.2378 0.2378
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0133 0.0466
Trypanosoma cruzi aldo/keto reductase, putative 0.0058 0.0402 0.0382
Loa Loa (eye worm) tubulin beta-1 chain 0.1197 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0311 0.0307
Echinococcus granulosus lamin dm0 0.002 0.0077 0.0069
Echinococcus multilocularis GPCR, family 2 0.0049 0.0321 0.0312
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Echinococcus multilocularis JmjC domain containing protein 4 0.0013 0.0021 0.0013
Brugia malayi alpha-tubulin 0.0927 0.772 0.772
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0087 0.0087
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0047 0.0311 0.0302
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0321 0.0312
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0055 0.0372 0.0364
Loa Loa (eye worm) AGC/NDR protein kinase 0.0047 0.0311 0.0311
Brugia malayi protein kinase C II. 0.0047 0.0311 0.0311
Leishmania major zeta tubulin, putative 0.0285 0.2317 0.2308
Echinococcus granulosus tubulin subunit beta 0.1197 1 1
Brugia malayi ecdysteroid receptor 0.0018 0.006 0.006
Leishmania major beta tubulin 0.1197 1 1
Schistosoma mansoni serine/threonine-protein kinase 0.0088 0.0656 0.0653
Echinococcus granulosus muscleblind protein 0.0282 0.2287 0.2281
Brugia malayi Synapsin, ATP binding domain containing protein 0.0139 0.1082 0.1082
Brugia malayi nuclear hormone receptor 0.0018 0.006 0.006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.006 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0133 0.0466
Brugia malayi NADH-dependent xylose reductase 0.0058 0.0402 0.0402
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0047 0.0311 0.0302
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.006 0.0051
Loa Loa (eye worm) oxidoreductase 0.0201 0.1606 0.1606
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Echinococcus granulosus Tubulin beta 2C chain 0.1197 1 1
Brugia malayi Tubulin beta chain 0.0372 0.3046 0.3046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0038 0.0234 0.0223
Chlamydia trachomatis 1,4-alpha-glucan branching enzyme 0.0054 0.037 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0013 0.0021 0.001
Toxoplasma gondii alpha-tubulin I, putative 0.0927 0.772 0.7718
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0201 0.1606 0.1596
Giardia lamblia Epsilon tubulin 0.0285 0.2317 0.2259
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0047 0.0311 0.0302
Echinococcus granulosus dnaJ subfamily B 0.0399 0.3272 0.3266
Trypanosoma brucei beta tubulin 0.0657 0.5451 0.5442
Trypanosoma brucei epsilon tubulin 0.0657 0.5451 0.5442
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0008
Schistosoma mansoni tubulin subunit beta 0.0285 0.2317 0.2314
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0016 0.0049 0.0164
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.006 0.0056
Brugia malayi Heterochromatin protein 1 0.0064 0.0447 0.0447
Schistosoma mansoni lipoxygenase 0.0288 0.2338 0.2335
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0084 0.0617 0.0609
Schistosoma mansoni tubulin subunit alpha 0.0927 0.772 0.7719
Trypanosoma brucei protein kinase, putative 0.0047 0.0305 0.0285
Echinococcus multilocularis tubulin alpha 1C chain 0.0927 0.772 0.7718
Schistosoma mansoni tubulin subunit epsilon 0.0657 0.5451 0.545
Schistosoma mansoni smdr2 0.0012 0.0011 0.0008
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus multilocularis lysine specific demethylase 6a 0.0013 0.0021 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0293 0.2378 0.2369
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.006 0.0051
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0077 0.0077
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0187 0.1487 0.1487
Loa Loa (eye worm) hypothetical protein 0.0201 0.1606 0.1606
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0055 0.0372 0.0372
Giardia lamblia Kinase, AGC PKA 0.0088 0.0656 0.0586
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0293 0.2378 0.2369
Echinococcus granulosus protein kinase C gamma type 0.0047 0.0311 0.0302
Echinococcus granulosus jumonji domain containing 1A 0.0013 0.0021 0.0013
Echinococcus multilocularis tubulin alpha chain 0.0927 0.772 0.7718
Leishmania major beta tubulin 0.1197 1 1
Mycobacterium tuberculosis Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidas 0.0013 0.0024 0.0054
Echinococcus granulosus tubulin alpha 1C chain 0.0927 0.772 0.7718
Schistosoma mansoni hypothetical protein 0.0533 0.4401 0.4398
Trichomonas vaginalis AGC family protein kinase 0.0293 0.2378 0.2369
Trypanosoma brucei aldo-keto reductase, putative 0.0201 0.1606 0.1588
Trichomonas vaginalis aldo/keto reductase, putative 0.0201 0.1606 0.1596
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.006 0.0051
Schistosoma mansoni intermediate filament proteins 0.002 0.0077 0.0073
Echinococcus multilocularis Tubulin alpha 1 chain 0.0927 0.772 0.7718
Trichomonas vaginalis alpha-amylase, putative 0.0013 0.0024 0.0013
Schistosoma mansoni lipoxygenase 0.0412 0.3383 0.338
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0305 0.0301
Trichomonas vaginalis tubulin epsilon chain, putative 0.0927 0.772 0.7718
Echinococcus granulosus nervana 2 0.0084 0.0617 0.0609
Echinococcus granulosus aldo keto reductase 0.0201 0.1606 0.1599
Loa Loa (eye worm) tubulin gamma chain 0.0657 0.5451 0.5451
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0047 0.0305 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0285 0.2317 0.2308
Echinococcus granulosus glucan 14 alpha branching enzyme 1 0.0054 0.037 0.0362
Trichomonas vaginalis tubulin epsilon chain, putative 0.1197 1 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0491 0.0491
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0641 0.5315 0.5315
Trichomonas vaginalis xanthine dehydrogenase, putative 0.02 0.1599 0.159
Echinococcus granulosus GPCR family 2 0.0049 0.0321 0.0312
Plasmodium vivax tubulin gamma chain, putative 0.0657 0.5451 0.5446
Schistosoma mansoni hypothetical protein 0.0237 0.1912 0.1909
Entamoeba histolytica protein kinase, putative 0.0047 0.0311 0.0299
Leishmania major beta tubulin 0.1197 1 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0087 0.0075
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.006 0.0056
Schistosoma mansoni hypothetical protein 0.0068 0.0483 0.048
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0927 0.772 0.7718
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0013 0.0021 0.001
Trichomonas vaginalis alpha-amylase, putative 0.0123 0.0944 0.0933
Onchocerca volvulus 0.0201 0.1606 0.5266
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0182 0.0171
Trichomonas vaginalis AGC family protein kinase 0.0055 0.0372 0.0361
Echinococcus multilocularis phd:f box containing protein 0.0013 0.0021 0.0013
Brugia malayi Tubulin alpha chain 0.0285 0.2317 0.2317
Leishmania major alpha tubulin 0.0927 0.772 0.7718
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0372 0.3046 0.3038
Echinococcus granulosus tubulin alpha chain 0.0927 0.772 0.7718
Toxoplasma gondii exonuclease III APE 0.0021 0.0087 0.0075
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0285 0.2317 0.2308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0052 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0047 0.0311 0.0299
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0133 0.0466
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0201 0.1606 0.1606
Echinococcus granulosus Polycystic kidney disease protein 0.0069 0.0491 0.0483
Plasmodium falciparum aldehyde reductase, putative 0.0058 0.0402 0.0391
Brugia malayi beta-tubulin, identical 0.1197 1 1
Brugia malayi serine/threonine kinase 12 0.0293 0.2378 0.2378
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.006 0.006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0133 0.0474
Trichomonas vaginalis aldo-keto reductase, putative 0.0201 0.1606 0.1596
Trichomonas vaginalis tubulin, putative 0.0285 0.2317 0.2308
Schistosoma mansoni aldo-keto reductase 0.0201 0.1606 0.1602
Toxoplasma gondii LsmAD domain-containing protein 0.0055 0.0372 0.0361
Loa Loa (eye worm) hypothetical protein 0.0069 0.0491 0.0491
Echinococcus granulosus hypothetical protein 0.0201 0.1606 0.1599
Trichomonas vaginalis amylase, putative 0.0013 0.0024 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.006 0.006
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0201 0.1606 0.1596
Entamoeba histolytica protein kinase, putative 0.0055 0.0372 0.0361
Leishmania major beta tubulin 0.1197 1 1
Entamoeba histolytica alpha-amylase, putative 0.0013 0.0024 0.0013
Entamoeba histolytica aldose reductase, putative 0.0201 0.1606 0.1596
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0047 0.0311 0.0302
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0023 0.0012
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0187 0.1487 0.1479

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) = 99 % Effect on Oryza sativa (rice) assessed as growth rate at 1 uM relative to control ChEMBL. 27393060

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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