Detailed information for compound 1802636

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 191.226 | Formula: C11H13NO2
  • H donors: 0 H acceptors: 2 LogP: 2.12 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)/C=C(\c1cccnc1)/C
  • InChi: 1S/C11H13NO2/c1-3-14-11(13)7-9(2)10-5-4-6-12-8-10/h4-8H,3H2,1-2H3/b9-7-
  • InChiKey: VMZIMOZQKLXCHR-CLFYSBASSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0035 0.0151 0.0709
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0193 0.0193
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0162 0.571
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0043 0.0209 0.0916
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0164 0.0311
Brugia malayi mbt repeat family protein 0.0048 0.0249 0.1093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0041 0.0182
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Trypanosoma brucei metacaspase 0.0043 0.0215 0.1006
Loa Loa (eye worm) tumor suppressor 0.0324 0.2282 1
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0215 0.0435
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0108 0.0108
Echinococcus multilocularis RUN 0.0019 0.0038 0.0038
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0242 0.9371
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0267 0.056
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0242 0.3199
Loa Loa (eye worm) hypothetical protein 0.0043 0.0215 0.0942
Mycobacterium tuberculosis Probable dehydrogenase 0.0095 0.0599 0.0623
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0035 0.0151 0.0151
Schistosoma mansoni protein kinase 0.0073 0.0435 0.0435
Loa Loa (eye worm) MBCTL1 0.0055 0.0298 0.1308
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0041 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0041 0.0182
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0164 0.0766
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0015 0.0071
Schistosoma mansoni zinc finger protein 0.0015 0.0009 0.0009
Loa Loa (eye worm) acetyltransferase 0.015 0.1001 0.4389
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0049 0.0213
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Onchocerca volvulus Cell death protein 3 homolog 0.0084 0.0513 0.8524
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0164 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0227 0.8761
Loa Loa (eye worm) hypothetical protein 0.0027 0.0097 0.0424
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0209 0.0209
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0041 0.0182
Plasmodium falciparum metacaspase-like protein 0.0043 0.0215 0.828
Brugia malayi Doublecortin family protein 0.0019 0.0038 0.0166
Schistosoma mansoni coup transcription factor 0.002 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0103
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0022 0.0022
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0093 0.0093
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.0956 0.4475
Schistosoma mansoni patched 1 0.0043 0.0209 0.0209
Echinococcus multilocularis caspase 8 0.0043 0.0215 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0041 0.0064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0215 0.0435
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0812 0.5885 0.5885
Schistosoma mansoni nuclear hormone receptor 0.002 0.0041 0.0041
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0192 0.0899
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0211 0.0986
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0116 0.0747 0.0706
Brugia malayi Bromodomain containing protein 0.0044 0.0219 0.0959
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0115 0.074 0.074
Schistosoma mansoni polycystin 1-related 0.0019 0.0038 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0242 0.05
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0073 0.0435 0.2036
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0134 0.0086
Plasmodium falciparum flavoprotein subunit of succinate dehydrogenase 0.0021 0.0049 0.1609
Mycobacterium tuberculosis Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) 0.0021 0.0049 0.0051
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.1001 0.1001
Schistosoma mansoni blooms syndrome DNA helicase 0.0015 0.0004 0.0004
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0035 0.0035
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0045 0.0227 0.1062
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.031 0.0287
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0215 0.1006
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0151 0.0363
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0304 0.2136 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0016
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0127 0.0595
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0032 0.0133 0.173
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0239 0.1047
Echinococcus granulosus cpg binding protein 0.0062 0.0354 0.0354
Echinococcus granulosus CREB binding protein 0.0016 0.0015 0.0015
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0056 0.026
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0035 0.0036
Schistosoma mansoni hypothetical protein 0.0041 0.0198 0.0198
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0045 0.0227 0.0464
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0105 0.0671 0.0671
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0041 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0041 0.0182
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0004 0.0017
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0185 0.7093
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.1104 0.1104
Echinococcus multilocularis CREB binding protein 0.0016 0.0015 0.0015
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0041
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0022 0.0056 0.026
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0215 0.828
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0022 0.0056 0.0056
Schistosoma mansoni thyroid hormone receptor 0.002 0.0041 0.0041
Trichomonas vaginalis STE family protein kinase 0.0073 0.0435 0.0966
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0048 0.0223
Loa Loa (eye worm) hypothetical protein 0.0048 0.0253 0.1107
Mycobacterium tuberculosis Probable succinate dehydrogenase (flavoprotein subunit) SdhA (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogena 0.0021 0.0049 0.0051
Leishmania major hypothetical protein, conserved 0.0027 0.0096 0.0449
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0162 0.0162
Trypanosoma cruzi metacaspase, putative 0.0043 0.0215 0.1006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0402 0.0402
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0115 0.074 0.074
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0215 0.0435
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0105 0.067 0.0697
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0022 0.0056 0.0056
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0164 0.0164
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0022 0.0056 0.188
Schistosoma mansoni hypothetical protein 0.004 0.0193 0.0193
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0164 0.0766
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0035 0.0164
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0267 0.353
Echinococcus granulosus CREB binding protein 0.0105 0.0671 0.0671
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0031 0.0031
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0038 0.0167
Schistosoma mansoni lipoxygenase 0.0019 0.0038 0.0038
Echinococcus granulosus neuropeptide s receptor 0.0465 0.3327 0.3327
Mycobacterium tuberculosis Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate deh 0.0027 0.0096 0.01
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0041 0.0182
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0166
Trypanosoma brucei unspecified product 0.0034 0.0144 0.0676
Schistosoma mansoni hypothetical protein 0.0015 0.0009 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0041 0.0182
Brugia malayi Cell death protein 3 precursor 0.0084 0.0513 0.2246
Giardia lamblia DINP protein human, muc B family 0.0021 0.0048 0.0031
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0049 0.0258 0.0258
Mycobacterium ulcerans hypothetical protein 0.016 0.1076 0.1059
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0164 0.0311
Schistosoma mansoni hypothetical protein 0.0021 0.0049 0.0049
Entamoeba histolytica recQ family DNA helicase 0.0015 0.0004 0.0009
Echinococcus granulosus succinate dehydrogenase ubiquinone 0.0021 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0019 0.0038 0.0038
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0162 0.0307
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0227 0.2995
Brugia malayi hypothetical protein 0.0019 0.0038 0.0166
Schistosoma mansoni jumonji domain containing protein 0.0058 0.032 0.032
Echinococcus granulosus dnaJ subfamily B 0.0812 0.5885 0.5885
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0009 0.0009
Trichomonas vaginalis glutathione reductase, putative 0.0022 0.0056 0.005
Onchocerca volvulus 0.002 0.0041 0.0064
Trypanosoma brucei Metacaspase-4 0.0043 0.0215 0.1006
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0041 0.0041
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0021 0.0049 0.0197
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.031 0.0287
Brugia malayi jmjC domain containing protein 0.0015 0.0009 0.0038
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0045 0.0227 0.0227
Trichomonas vaginalis STE family protein kinase 0.0073 0.0435 0.0966
Echinococcus granulosus expressed conserved protein 0.0093 0.0582 0.0582
Schistosoma mansoni lipoxygenase 0.0054 0.0294 0.0294
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0049 0.0214
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0095 0.0599 0.0623
Echinococcus multilocularis cpg binding protein 0.0062 0.0354 0.0354
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0239 0.0249
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0182 0.6942
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0164 0.0311
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0035 0.0151 0.0709
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0045 0.0227 0.0236
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0022 0.0056 0.026
Echinococcus multilocularis protein dispatched 1 0.0049 0.0253 0.0253
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0267 0.0267
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0052 0.028 0.1225
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0239 0.1119
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0151 0.0281
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0211 0.0986
Leishmania major DNA polymerase kappa, putative 0.0021 0.0048 0.0223
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0215 0.2834
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0108 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0041 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Toxoplasma gondii hypothetical protein 0.0049 0.0257 0.3398
Brugia malayi tumor suppressor. 0.0324 0.2282 1
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.0358 0.0358
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0358 0.1571
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0041 0.0041
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0043 0.0215 0.0942
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0151 0.0281
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.032 0.032
Brugia malayi hypothetical protein 0.004 0.0193 0.0846
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0041 0.0182
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0242 0.0242
Schistosoma mansoni cpg binding protein 0.0062 0.0354 0.0354
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0358 0.0358
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0334 0.0311
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0249 0.3799
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0022 0.0056 0.0695
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0227 0.0236
Brugia malayi ecdysteroid receptor 0.002 0.0041 0.0182
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0009 0.0009
Leishmania major eukaryotic translation initiation factor-like 0.0035 0.0151 0.0709
Schistosoma mansoni loxhd1 0.0019 0.0038 0.0038
Echinococcus granulosus FTZ F1 alpha 0.002 0.0041 0.0041
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0009 0.0009
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0049 0.0258 0.0258
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0637 0.0637
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.058 0.4175 1
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0249 0.1093
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0108 0.0473
Loa Loa (eye worm) CBP-B 0.0075 0.0448 0.1962
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0027 0.0096 0.0096
Trypanosoma brucei metacaspase 5, putative 0.0043 0.0215 0.1006
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.012 0.0561
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0249 0.0249
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0022 0.0056 0.188
Mycobacterium tuberculosis Probable reductase 0.0095 0.0599 0.0623
Plasmodium vivax glutathione reductase, putative 0.0047 0.0239 0.9244
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0137
Plasmodium vivax metacaspase 1, putative 0.0043 0.0215 0.828
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0022 0.0022
Loa Loa (eye worm) inositol-1 0.0036 0.0162 0.0711
Onchocerca volvulus 0.004 0.0193 0.2786
Mycobacterium tuberculosis Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) (fumaric hydrogenase) 0.0021 0.0049 0.0051
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0192 0.0379
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0095 0.0599 0.0623
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0127 0.0595
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0041 0.0041
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.094 0.094
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0749 1
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0108 0.0108
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0316 0.1385
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0026 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0041 0.0182
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0164 0.0311
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0249 0.0249
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0045 0.0227 0.0464
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0267 0.056
Schistosoma mansoni hypothetical protein 0.0027 0.0097 0.0097
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0787 0.0787
Onchocerca volvulus 0.0048 0.0253 0.3858
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0041 0.0182
Schistosoma mansoni alpha-glucosidase 0.0141 0.0936 0.0936
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.1076 0.112
Plasmodium vivax flavoprotein subunit of succinate dehydrogenase, putative 0.0021 0.0049 0.1609
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0021 0.0049 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0041 0.0041
Trypanosoma brucei ISWI complex protein 0.0015 0.0009 0.0042
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0035 0.0151 0.0151
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1317 0.9609 1
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0009 0.0009
Echinococcus multilocularis dnaJ subfamily B 0.0812 0.5885 0.5885
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Schistosoma mansoni caspase-7 (C14 family) 0.0084 0.0513 0.0513
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2136 1
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0249 0.0249
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0041 0.0182
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0009 0.0038
Plasmodium falciparum glutathione reductase 0.0047 0.0239 0.9244
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0022 0.0057 0.0057
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0032 0.0133 0.173
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0035 0.0151 0.1981
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0334 0.0348
Echinococcus multilocularis tumor protein p63 0.0331 0.2336 0.2336
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0038 0.0038
Echinococcus multilocularis caspase 2 0.0084 0.0513 0.0513
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0227 0.1062
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0045 0.0227 0.0995
Brugia malayi TAZ zinc finger family protein 0.0105 0.0671 0.2943
Echinococcus granulosus caspase 3 0.0071 0.0421 0.0421
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0151 0.0363
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.058 0.4175 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0185 0.0444
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0009 0.0009
Brugia malayi steroid hormone receptor 0.002 0.0041 0.0182
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0041 0.0041
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0038 0.0038
Brugia malayi jmjC domain containing protein 0.0063 0.0358 0.1571
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.003 0.012 0.0526
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0022 0.0056 0.0058
Brugia malayi PHD-finger family protein 0.0034 0.0143 0.0629
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.031 0.1358
Loa Loa (eye worm) hypothetical protein 0.0071 0.042 0.1842
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.3327 0.3327
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Brugia malayi jmjC domain containing protein 0.0015 0.0009 0.0038
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0164 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0215 0.0435
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0192 0.0899
Echinococcus multilocularis zinc finger protein 0.0028 0.0104 0.0104
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0108 0.0473
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0048 0.005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0056 0.0922
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0009 0.0009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.1104 0.484
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0022 0.0056 0.003
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0164 0.0311
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1362 0.9941 1
Trypanosoma cruzi metacaspase, putative 0.0043 0.0215 0.1006
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0009 0.0009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0041 0.0041
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0038 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.012 0.0561
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0015 0.0071
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0164 0.0311
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0027 0.0096 0.0449
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0334 0.4432
Leishmania major metacaspase, putative 0.0043 0.0215 0.1006
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0035 0.0151 0.0151
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0041 0.0041
Echinococcus granulosus zinc finger protein 0.0028 0.0104 0.0104
Echinococcus multilocularis CREB binding protein 0.0016 0.0015 0.0015
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0041 0.0041
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0162 0.0162
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0239 0.9244
Echinococcus multilocularis CREB binding protein 0.0016 0.0015 0.0015
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0334 0.1563
Schistosoma mansoni ap endonuclease 0.0019 0.0035 0.0035
Echinococcus granulosus hypothetical protein 0.0027 0.0097 0.0097
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0035 0.0075
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0041 0.0041
Toxoplasma gondii succinate dehydrogenase [ubiquinone] iron-sulfur protein 0.0049 0.0258 0.341
Leishmania major succinate dehydrogenase, putative 0.0032 0.0128 0.0598
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0215 0.0435
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0201 0.0401
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0162 0.0389
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase iron-sulfur subunit 0.0049 0.0258 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0022 0.0056 0.003
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.3327 0.3327
Echinococcus granulosus tumor protein p63 0.0331 0.2336 0.2336
Brugia malayi Thioredoxin reductase 0.0047 0.0239 0.1047
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0164 0.0392
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0249 0.0249
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0041 0.0041
Schistosoma mansoni CREB-binding protein 2 0.0105 0.0671 0.0671
Toxoplasma gondii NADPH-glutathione reductase 0.0022 0.0056 0.0695
Schistosoma mansoni inositol monophosphatase 0.0036 0.0162 0.0162
Trypanosoma brucei metacaspase MCA2 0.0043 0.0215 0.1006
Trypanosoma brucei metacaspase MCA3 0.0043 0.0215 0.1006
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0209 0.0209
Plasmodium falciparum iron-sulfur subunit of succinate dehydrogenase 0.0049 0.0258 1
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0045 0.0227 0.0203
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0022 0.0022
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0151 0.0281
Brugia malayi Temporarily assigned gene name protein 44 0.0027 0.0097 0.0427
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0192 0.0899
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0211 0.0986
Echinococcus granulosus protein quaking 0.0027 0.0097 0.0097
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0151 0.0281
Echinococcus granulosus CREB binding protein 0.0067 0.0391 0.0391
Loa Loa (eye worm) glutathione reductase 0.0047 0.0239 0.1047
Giardia lamblia Kinase, STE STE20 0.0073 0.0435 0.0966
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit, putative 0.0032 0.0128 0.0598
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0009 0.0038
Schistosoma mansoni succinate dehydrogenase 0.0021 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0041 0.0182
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0035 0.001
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0048 0.0223
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0941 0.0941
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0267 0.056
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0041 0.0182
Loa Loa (eye worm) RecQ helicase 0.0041 0.0201 0.088
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.031 0.145
Loa Loa (eye worm) hypothetical protein 0.0051 0.0275 0.1206
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0282 0.1235
Giardia lamblia NADH oxidase lateral transfer candidate 0.0022 0.0056 0.005
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0035 0.0084
Echinococcus multilocularis protein patched 0.0043 0.0209 0.0209
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.094 0.094
Toxoplasma gondii exonuclease III APE 0.0019 0.0035 0.042
Brugia malayi polk-prov protein 0.003 0.012 0.0526
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0009 0.0009
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0211 0.0986
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0073 0.0435 0.1906
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0108 0.1398
Brugia malayi Inositol-1 0.0036 0.0162 0.0711
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.0956 0.4475
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0045 0.0227 0.0995
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0009 0.0067
Leishmania major succinate dehydrogenase flavoprotein, putative 0.0021 0.0049 0.0229
Echinococcus granulosus caspase 8 0.0043 0.0215 0.0215
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0162 0.0307
Loa Loa (eye worm) hypothetical protein 0.0055 0.0298 0.1308
Schistosoma mansoni hypothetical protein 0.0027 0.0097 0.0097
Brugia malayi nuclear receptor NHR-88 0.002 0.0041 0.0182
Trypanosoma cruzi Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0049 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0041 0.0182
Echinococcus granulosus RUN 0.0019 0.0038 0.0038
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0242 0.3199
Echinococcus granulosus caspase 2 0.0084 0.0513 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0201 0.088
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0045 0.0227 0.0544
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0009 0.0041
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0294 0.0294
Schistosoma mansoni DNA helicase recq5 0.0029 0.0108 0.0108
Trypanosoma cruzi metacaspase, putative 0.0043 0.0215 0.1006
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0108 0.1398
Loa Loa (eye worm) hypothetical protein 0.0046 0.0237 0.1038
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Echinococcus granulosus dna polymerase kappa 0.004 0.0192 0.0192
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0041 0.0041
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0004 0.0017
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0298 0.0298
Trichomonas vaginalis mercuric reductase, putative 0.0022 0.0056 0.005
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0073 0.0435 0.1906
Loa Loa (eye worm) hypothetical protein 0.0029 0.0108 0.0473
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0038 0.0166
Schistosoma mansoni hypothetical protein 0.0041 0.0198 0.0198
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0284 0.1986 0.1958
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0267 0.1169
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0041 0.0182
Trypanosoma cruzi ISWI complex protein 0.0015 0.0009 0.0042
Trypanosoma brucei trypanothione reductase 0.0047 0.0239 0.1119
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Schistosoma mansoni alpha glucosidase 0.0036 0.0164 0.0164
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0022 0.0056 0.1431
Schistosoma mansoni microtubule-associated protein tau 0.137 1 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0513 0.2246
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0035 0.0164
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0041 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0038 0.1169
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0267 0.0267
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0022 0.0056 0.003
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0041 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0031 0.0031
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0022 0.0056 0.188
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1104 0.1104
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0042
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0009 0.0067
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0009 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.028 0.1308
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0108 0.0473
Plasmodium falciparum glutathione reductase 0.0022 0.0056 0.188
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0227 0.8761
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0041 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0022 0.0056 0.026
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0127 0.0595
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0402 0.0402
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0087 0.0087
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0192 0.0168
Brugia malayi jmjC domain containing protein 0.0015 0.0009 0.0038
Brugia malayi nuclear hormone receptor 0.002 0.0041 0.0182
Chlamydia trachomatis succinate dehydrogenase iron sulfur subunit 0.0027 0.0096 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1104 0.1104
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0185 0.0363
Schistosoma mansoni cpg binding protein 0.0062 0.0354 0.0354
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.0358 0.0358
Echinococcus multilocularis dna polymerase kappa 0.004 0.0192 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0267 0.056
Echinococcus granulosus phd:f box containing protein 0.0015 0.0009 0.0009
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0022 0.0056 0.0243
Schistosoma mansoni zinc finger protein 0.0028 0.0104 0.0104
Leishmania major eukaryotic translation initiation factor-like protein 0.0035 0.0151 0.0709
Schistosoma mansoni alpha-glucosidase 0.0141 0.0936 0.0936
Trichomonas vaginalis STE family protein kinase 0.0073 0.0435 0.0966
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0035 0.0035
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0215 0.2834
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0227 0.1062
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0035 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0215 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0041 0.0182
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0134 0.014
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0164 0.2147
Toxoplasma gondii thioredoxin reductase 0.0047 0.0239 0.3157
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0215 0.1006
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0334 0.0334
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0041 0.0064
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0267 0.1249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0041 0.0182
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1362 0.9941 1
Echinococcus granulosus bloom syndrome protein 0.0041 0.0201 0.0201
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0021 0.0049 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0294 0.0294
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0201 0.0401
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0041 0.0182
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0298 0.1308
Brugia malayi glutathione reductase 0.0047 0.0239 0.1047
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0038
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0105 0.067 0.0697
Trypanosoma brucei protein kinase, putative 0.005 0.0267 0.1249
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0035 0.1055
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.1104 0.484
Trypanosoma cruzi ISWI complex protein 0.0015 0.0009 0.0042
Leishmania major mitochondrial DNA polymerase beta 0.0304 0.2136 1
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0032 0.0128 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0267 0.0267
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0298 0.0298
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0009 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0009 0.0038
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0249 0.0249
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Brugia malayi CHE-14 protein 0.0043 0.0209 0.0916
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Schistosoma mansoni hypothetical protein 0.0041 0.0198 0.0198
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0108 0.3981
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0164 0.0311
Echinococcus granulosus dual specificity mitogen activated protein 0.0073 0.0435 0.0435
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0162 0.0759
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0267 0.1249
Giardia lamblia Fructose-bisphosphate aldolase 0.058 0.4175 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Brugia malayi Bromodomain containing protein 0.0084 0.0515 0.2258
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0162 0.0759
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0031 0.0031
Echinococcus multilocularis microtubule associated protein 2 0.137 1 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0626 0.2744
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0144 0.0676
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0334 0.0311
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0215 0.2834
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0626 0.2744
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0056 0.026
Plasmodium falciparum thioredoxin reductase 0.0022 0.0056 0.188
Brugia malayi succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial 0.0049 0.0258 0.113
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0151 0.0709
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0267 0.056
Schistosoma mansoni rab6-interacting 0.0019 0.0038 0.0038
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0041 0.0182
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit 0.0027 0.0096 0.0449
Toxoplasma gondii flavoprotein subunit of succinate dehydrogenase 0.0021 0.0049 0.0605
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0073 0.0435 0.2036
Brugia malayi jmjC domain containing protein 0.0058 0.032 0.1403
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0041 0.0041
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0298 0.0298
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0298 0.0298
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.3327 0.3327
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0243 0.0243
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0116 0.0747 0.0778
Schistosoma mansoni inositol monophosphatase 0.0036 0.0162 0.0162
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0087 0.0087
Echinococcus multilocularis dual specificity mitogen activated protein 0.0073 0.0435 0.0435
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0127 0.0222
Brugia malayi MAP kinase sur-1 0.005 0.0267 0.1169
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0049 0.0258 0.0258
Schistosoma mansoni cpg binding protein 0.0057 0.0316 0.0316
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0334 0.0334
Echinococcus multilocularis CREB binding protein 0.0074 0.0441 0.0441
Echinococcus multilocularis caspase 0.0115 0.074 0.074
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0209 0.042
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0035 0.0153
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0626 0.1499
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2136 1
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0201 0.0201
Loa Loa (eye worm) succinate-ubiquinone oxidoreductase 0.0021 0.0049 0.0214
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0334 0.0311
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0038
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Loa Loa (eye worm) hypothetical protein 0.004 0.0193 0.0846
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0022 0.0056 0.0056
Schistosoma mansoni bromodomain containing protein 0.0072 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.079
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.1318 0.1318
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.1001 0.4389
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0038 0.0038
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase flavoprotein subunit 0.0021 0.0049 0.062
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0041 0.0182
Plasmodium falciparum metacaspase 1 0.0043 0.0215 0.828
Echinococcus granulosus succinate dehydrogenase (ubiquinone) iron sulfur 0.0049 0.0258 0.0258
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0162 0.0138
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0026 0.0026
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0041 0.0041
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0108 0.0176
Trypanosoma cruzi NADH dehydrogenase, putative 0.0032 0.0133 0.0621
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.058 0.4175 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0038
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0073 0.0435 0.2036
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0209 0.0209
Schistosoma mansoni DNA helicase recq1 0.0029 0.0108 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0192 0.0899
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0162 0.0162
Trypanosoma brucei NADH dehydrogenase 0.0032 0.0133 0.0621
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0242 0.05
Schistosoma mansoni caspase-3 (C14 family) 0.0115 0.074 0.074
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0108 0.0108
Brugia malayi hypothetical protein 0.0019 0.0038 0.0166
Trypanosoma brucei glucosidase, putative 0.0036 0.0164 0.0766
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0041 0.0182
Treponema pallidum NADH oxidase 0.0022 0.0056 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0041 0.0182
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0041 0.0041
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0022 0.0056 0.0922
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0021 0.0049 0.0197
Schistosoma mansoni thyroid hormone receptor 0.002 0.0041 0.0041
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0164 0.0718
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.031 0.0322
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0027 0.0097 0.0427
Mycobacterium tuberculosis Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) 0.0018 0.0025 0.0027
Brugia malayi hypothetical protein 0.0027 0.0097 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0015 0.0071
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0035 0.0164
Schistosoma mansoni caspase-7 (C14 family) 0.0115 0.074 0.074
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0105 0.067 0.0628
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0243 0.0243
Trypanosoma cruzi succinate dehydrogenase, putative 0.0032 0.0128 0.0598
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) 0.0021 0.0049 0.0049
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0116 0.0747 0.0778
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0192 0.0379
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0032 0.0133 0.0108
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.032 0.032
Brugia malayi jmjC domain containing protein 0.0015 0.0009 0.0038
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0127 0.0304
Mycobacterium ulcerans succinate dehydrogenase iron-sulfur subunit 0.0027 0.0096 0.0071
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0041 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0164 0.0311
Leishmania major trypanothione reductase 0.0047 0.0239 0.1119
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0041 0.0041
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0162 0.0162
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0066 0.0288
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0022 0.0022
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0073 0.0934
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0227 0.1062
Loa Loa (eye worm) succinate dehydrogenase iron-sulfur protein 0.0049 0.0258 0.113
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0041 0.0041
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0162 0.0759
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0031 0.0031
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0041 0.0064
Echinococcus granulosus caspase 0.0115 0.074 0.074
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0164 0.0766
Plasmodium falciparum thioredoxin reductase 0.0047 0.0239 0.9244
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0284 0.1986 0.2067
Mycobacterium leprae Probable succinate dehydrogenase (iron-sulfur protein subunit) SdhB (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHY 0.0027 0.0096 0.0048
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0022 0.0056 0.026
Echinococcus multilocularis expressed conserved protein 0.0093 0.0582 0.0582
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0041 0.0041
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.031 0.031
Trypanosoma cruzi metacaspase, putative 0.0043 0.0215 0.1006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0215 0.0435
Onchocerca volvulus 0.0048 0.0249 0.3799
Loa Loa (eye worm) hypothetical protein 0.0048 0.0249 0.1093
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0043 0.0215 0.0215
Echinococcus multilocularis caspase 3 0.0071 0.0421 0.0421
Schistosoma mansoni ap endonuclease 0.0019 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0041 0.0198 0.0198
Onchocerca volvulus 0.0095 0.0595 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0334 0.0334
Brugia malayi translation initiation factor 4E 0.0035 0.0151 0.0663
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.0956 0.4475
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0032 0.0133 0.4976
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0249 0.0249
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0162 0.2127
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0151 0.0709
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0182
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0022 0.0056 0.026
Echinococcus granulosus CREB binding protein 0.0016 0.0015 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0022 0.0056 0.026
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0038 0.1169
Schistosoma mansoni hypothetical protein 0.0296 0.2075 0.2075
Mycobacterium tuberculosis Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase) 0.0027 0.0096 0.01
Brugia malayi CXXC zinc finger family protein 0.0057 0.0316 0.1385
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0192 0.0899
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0253 0.0253
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0077 0.276
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0267 0.1249
Onchocerca volvulus 0.0057 0.0316 0.4995
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0249 0.0249
Leishmania major NADH dehydrogenase, putative 0.0032 0.0133 0.0621
Schistosoma mansoni rab6-interacting 0.0019 0.0038 0.0038
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0267 0.1249
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0049 0.0214
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.1001 0.1001
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0041 0.0041
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0192 0.0899
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0041 0.0041
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.032 0.032
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0009 0.0041
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0022 0.0056 0.188
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0192 0.0899
Loa Loa (eye worm) hypothetical protein 0.0047 0.0239 0.1048
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0032 0.0133 0.4976
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0209 0.0916
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0022 0.0056 0.026
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0035 0.1055
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0045 0.0227 0.0227
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0022 0.0056 0.026
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0164 0.0718
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.1318 0.1318
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0045 0.0227 0.0227
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0045 0.0227 0.018
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0192 0.0168
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0032 0.0128 0.0598
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0267 0.0267
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0267 0.1249
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0035 0.0153
Plasmodium vivax iron-sulfur subunit of succinate dehydrogenase, putative 0.0049 0.0258 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0105 0.067 0.0697
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0047 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0041 0.0182
Trypanosoma cruzi NADH dehydrogenase, putative 0.0032 0.0133 0.0621
Brugia malayi mbt repeat family protein 0.0048 0.0249 0.1093
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0041 0.0041
Treponema pallidum fructose-bisphosphate aldolase 0.058 0.4175 1
Trypanosoma brucei Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0021 0.0049 0.0229
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.031 0.031
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0047 0.0047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0267 0.1249
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0087 0.0087
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0026 0.0112
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0009 0.0009
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0267 0.1249
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0038 0.0038
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0164 0.0311
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0193 0.0193
Echinococcus multilocularis protein quaking 0.0027 0.0097 0.0097
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0284 0.1986 0.1977
Loa Loa (eye worm) translation initiation factor 4E 0.0035 0.0151 0.0663
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0045 0.0227 0.0544
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0162 0.0759
Echinococcus multilocularis succinate dehydrogenase iron sulfur protein 0.0027 0.0096 0.0096
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0626 0.0626
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0162 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0041 0.0182

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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