Detailed information for compound 1819920

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 256.341 | Formula: C13H24N2O3
  • H donors: 3 H acceptors: 3 LogP: 1.3 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: ONC(=O)CCCCCCC(=O)NC1CCCC1
  • InChi: 1S/C13H24N2O3/c16-12(14-11-7-5-6-8-11)9-3-1-2-4-10-13(17)15-18/h11,18H,1-10H2,(H,14,16)(H,15,17)
  • InChiKey: PRACZKROELLVMQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histone deacetylase 3 References
Homo sapiens histone deacetylase 1 Starlite/ChEMBL References
Homo sapiens histone deacetylase 8 Starlite/ChEMBL References
Homo sapiens histone deacetylase 6 Starlite/ChEMBL References
Homo sapiens nuclear receptor corepressor 2 Starlite/ChEMBL References
Homo sapiens histone deacetylase 10 Starlite/ChEMBL References
Homo sapiens histone deacetylase 2 Starlite/ChEMBL References
Homo sapiens histone deacetylase 11 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium yoelii histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Giardia lamblia Histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum RPD3/HD1 histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 10, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans strong similarity to S. cerevisiae HDA1 (YNL021W) class II histone deacetylase HDA1 complex subunit Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum Histone deacetylase 4, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium falciparum histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Neospora caninum hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum ko:K06067 histone deacetylase 1/2, putative Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus nuclear receptor co repressor related ncor Get druggable targets OG5_131772 All targets in OG5_131772
Plasmodium knowlesi histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Toxoplasma gondii histone deacetylase HDAC1 Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi Histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 6, putative Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium parvum histone deacetylase HDA2/Rpd3p Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Toxoplasma gondii histone deacetylase HDAC2 Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Theileria parva hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC4 Get druggable targets OG5_129938 All targets in OG5_129938
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus granulosus histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Babesia bovis histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase 3 Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium falciparum histone deacetylase 2 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma congolense histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Brugia malayi Histone deacetylase family protein Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi Histone deacetylase family protein Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum IPR000286,Histone deacetylase superfamily;IPR013838,Beta tubulin, autoregulation binding site,domain-containing Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 10, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma brucei histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) histone deacetylase 7A Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 6 Get druggable targets OG5_126654 All targets in OG5_126654
Trypanosoma brucei histone deacetylase 4 Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum ko:K01463 Hdac3 [EC:3.5.1.-], putative Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC3 Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium yoelii Histone deacetylase family, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis nuclear receptor co repressor related (ncor) Get druggable targets OG5_131772 All targets in OG5_131772
Schistosoma japonicum Histone deacetylase 6, putative Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129938 All targets in OG5_129938
Loa Loa (eye worm) histone deacetylase 11 Get druggable targets OG5_129938 All targets in OG5_129938
Echinococcus multilocularis histone deacetylase 7 Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi histone deacetylase 1 (HD1) Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma japonicum Histone deacetylase 4, putative Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium yoelii histone deacetylase/AcuC/AphA family protein, putative Get druggable targets OG5_129938 All targets in OG5_129938
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi histone deacetylase 11 Get druggable targets OG5_129938 All targets in OG5_129938
Plasmodium knowlesi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei gambiense histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase 4 5 Get druggable targets OG5_126654 All targets in OG5_126654
Loa Loa (eye worm) histone deacetylase Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium knowlesi histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium parvum histone deactylase of possible bacterial origin with ankyrin repeats at the N-terminus Get druggable targets OG5_126654 All targets in OG5_126654
Theileria parva histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase hda2 Get druggable targets OG5_126654 All targets in OG5_126654
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum hypothetical protein Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase, putative Get druggable targets OG5_129938 All targets in OG5_129938
Brugia malayi histone deacetylase 3 (HD3) Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Leishmania major histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium falciparum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Neospora caninum hypothetical protein Get druggable targets OG5_129938 All targets in OG5_129938
Trypanosoma brucei histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans strong similarity to S. cerevisiae HDA1 (YNL021W) class II histone deacetylase HDA1 complex subunit Get druggable targets OG5_126654 All targets in OG5_126654
Echinococcus multilocularis histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei gambiense histone deacetylase 1,histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 7 Get druggable targets OG5_126654 All targets in OG5_126654
Plasmodium knowlesi histone deacetylase, putative Get druggable targets OG5_129938 All targets in OG5_129938
Babesia bovis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126654 All targets in OG5_126654
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase 2, putative Get druggable targets OG5_126654 All targets in OG5_126654
Schistosoma mansoni histone deacetylase 4 5 Get druggable targets OG5_126654 All targets in OG5_126654
Entamoeba histolytica histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase, putative Get druggable targets OG5_129938 All targets in OG5_129938
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi histone deacetylase, putative histone deacetylase 3 428 aa 374 aa 30.5 %
Brugia malayi Histone deacetylase family protein histone deacetylase 11 296 aa 290 aa 24.5 %
Plasmodium falciparum histone deacetylase 1 histone deacetylase 8 286 aa 241 aa 44.8 %
Trypanosoma brucei histone deacetylase 2 histone deacetylase 2 488 aa 427 aa 29.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0475 0.1876
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0207 0.0198
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0086 0.0616 0.123
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0038 0.0207 0.0198
Echinococcus granulosus transient receptor potential gamma protein 0.0038 0.0207 0.0198
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0028 0.0117 0.0233
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0038 0.0207 0.0776
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0038 0.0207 0.0776
Echinococcus granulosus voltage dependent calcium channel 0.0038 0.0207 0.0198
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0207 0.0198
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.002 0.0052 0.0043
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0115 0.0868 0.336
Onchocerca volvulus 0.0086 0.0616 0.1323
Loa Loa (eye worm) hypothetical protein 0.0092 0.0674 0.1346
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0115 0.0868 0.3376
Schistosoma mansoni transient receptor potential channel 4 0.0038 0.0207 0.0198
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0038 0.0207 0.0198
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0057 0.0188
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0012 0.0024
Schistosoma mansoni lamin 0.0015 0.0011 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.027 0.1004
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0207 0.0198
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0173 0.056
Entamoeba histolytica aldose reductase, putative 0.0026 0.0106 0.0356
Echinococcus granulosus mothers against decapentaplegic 5 0.0015 0.0012 0.0003
Echinococcus granulosus hyperpolarization activated cyclic 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0042 0.024 0.0478
Echinococcus multilocularis histone deacetylase 7 0.0231 0.1867 0.1859
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0046 0.0273 0.0899
Echinococcus multilocularis smad 0.0015 0.0012 0.0003
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0086 0.0616 0.1314
Brugia malayi Bromodomain containing protein 0.0046 0.0275 0.0532
Plasmodium falciparum basic transcription factor 3b, putative 0.0023 0.0073 0.0252
Echinococcus multilocularis transfer RNA-Gly 0.0038 0.0207 0.0198
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0207 0.0198
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trichomonas vaginalis histone deacetylase, putative 0.0311 0.2553 1
Brugia malayi beta-lactamase 0.0086 0.0616 0.1213
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0173 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0026 0.0106 0.0193
Mycobacterium leprae Conserved hypothetical protein 0.0019 0.004 0.0101
Brugia malayi jmjC domain containing protein 0.0056 0.0365 0.071
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0207 0.0198
Trichomonas vaginalis histone deacetylase, putative 0.0311 0.2553 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0311 0.2553 1
Echinococcus multilocularis shaker cognate 0.0038 0.0207 0.0198
Echinococcus granulosus histone deacetylase 8 0.0146 0.1136 0.1128
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Echinococcus granulosus histone deacetylase 6 0.0239 0.1931 0.1923
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0025 0.0097 0.0343
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0173 0.0622
Plasmodium vivax histone deacetylase 1, putative 0.0311 0.2553 0.8675
Echinococcus granulosus histone deacetylase 7 0.0231 0.1867 0.1859
Mycobacterium ulcerans beta-lactamase 0.0086 0.0616 0.2452
Schistosoma mansoni histone deacetylase 1 2 3 0.0146 0.1136 0.1128
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0028 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.1073 0.1065
Trichomonas vaginalis ap endonuclease, putative 0.0025 0.0097 0.0319
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Trypanosoma cruzi histone deacetylase, putative 0.0146 0.1136 0.443
Onchocerca volvulus 0.0016 0.0016 0.0011
Echinococcus multilocularis potassium large conductance calcium activated 0.0038 0.0207 0.0198
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0207 0.0198
Echinococcus granulosus ubiquitin specific protease 41 0.0021 0.0057 0.0048
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0207 0.0198
Brugia malayi hypothetical protein 0.0094 0.0686 0.1354
Trypanosoma brucei histone deacetylase 4 0.0231 0.1867 0.7304
Schistosoma mansoni smad1 5 8 and 0.0015 0.0012 0.0003
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0016 0.0016 0.0031
Toxoplasma gondii histone deacetylase HDAC2 0.0311 0.2553 0.8675
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0025 0.0097 0.0193
Loa Loa (eye worm) oxidoreductase 0.0026 0.0106 0.0212
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0202 0.0193
Brugia malayi olfactory channel protein osm-9 0.0038 0.0207 0.0395
Echinococcus granulosus chromobox protein 1 0.0049 0.0304 0.0295
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0967 0.0959
Loa Loa (eye worm) hypothetical protein 0.0027 0.0111 0.0221
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0115 0.0868 0.086
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0068 0.0136
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0038 0.0207 0.0395
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0207 0.0395
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0026 0.0106 0.0193
Toxoplasma gondii PHD-finger domain-containing protein 0.0017 0.0028 0.0063
Brugia malayi Cyclic-nucleotide gated cation channel 0.0038 0.0207 0.0395
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0016 0.0016 0.0022
Onchocerca volvulus 0.0026 0.0106 0.0208
Echinococcus granulosus histone deacetylase 6 0.0231 0.1867 0.1859
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0073 0.0227
Echinococcus multilocularis two pore calcium channel protein 2 0.0038 0.0207 0.0198
Onchocerca volvulus 0.0026 0.0106 0.0208
Trichomonas vaginalis esterase, putative 0.0086 0.0616 0.2366
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Mycobacterium ulcerans hypothetical protein 0.0086 0.0616 0.2452
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0038 0.0207 0.0776
Echinococcus multilocularis aldo keto reductase 0.0026 0.0106 0.0097
Onchocerca volvulus Heterochromatin protein 1 homolog 0.003 0.0135 0.0273
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0025 0.0097 0.0343
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0115 0.0868 0.3376
Echinococcus granulosus peregrin 0.0023 0.0075 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0057 0.0164
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0115 0.0868 0.086
Leishmania major histone deacetylase, putative 0.0311 0.2553 1
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.003 0.0133 0.0266
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0173 0.056
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0207 0.0198
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0475 0.0466
Onchocerca volvulus Histone deacetylase 10 homolog 0.0146 0.1136 0.246
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0207 0.0198
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0173 0.0645
Trichomonas vaginalis immunophilin, putative 0.0115 0.0868 0.336
Schistosoma mansoni immunophilin 0.0099 0.0732 0.0723
Brugia malayi Bromodomain containing protein 0.0026 0.0099 0.018
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0038 0.0207 0.0395
Echinococcus granulosus calcium activated potassium channel 0.0038 0.0207 0.0198
Schistosoma mansoni 6-phosphofructokinase 0.0127 0.0967 0.0959
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0057 0.0096
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0115 0.0868 0.336
Brugia malayi ImpB/MucB/SamB family protein 0.0071 0.0494 0.0969
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0025 0.0097 0.0177
Echinococcus granulosus aldo keto reductase 0.0026 0.0106 0.0097
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0038 0.0207 0.0412
Echinococcus multilocularis dna polymerase kappa 0.0037 0.02 0.0191
Echinococcus granulosus sodium channel protein 0.0038 0.0207 0.0198
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Trichomonas vaginalis histone deacetylase, putative 0.0311 0.2553 1
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0016 0.0016 0.0025
Toxoplasma gondii histone deacetylase HDAC4 0.0356 0.2941 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.012 0.0239
Leishmania major DNA polymerase eta, putative 0.0071 0.0494 0.1905
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0038 0.0207 0.0428
Trichomonas vaginalis penicillin-binding protein, putative 0.0086 0.0616 0.2366
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0015 0.0012 0.0003
Mycobacterium ulcerans 6-phosphofructokinase 0.0127 0.0967 0.3885
Echinococcus multilocularis aldo keto reductase 0.0026 0.0106 0.0097
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0015 0.0011 0.0022
Schistosoma mansoni Smad4 0.0015 0.0012 0.0003
Onchocerca volvulus 0.0038 0.0207 0.0428
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0173 0.0622
Loa Loa (eye worm) MH2 domain-containing protein 0.0226 0.1821 0.3634
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Onchocerca volvulus 0.0086 0.0616 0.1323
Giardia lamblia DINP protein human, muc B family 0.0037 0.02 0.0727
Schistosoma mansoni hypothetical protein 0.0017 0.0028 0.0019
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0127 0.0967 0.3765
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0317 0.1051
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0026 0.0106 0.0193
Echinococcus multilocularis peregrin 0.0023 0.0075 0.0065
Brugia malayi hypothetical protein 0.0038 0.0207 0.0395
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0038 0.0207 0.0395
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0016 0.0016 0.0013
Schistosoma mansoni transcription factor btf3 0.0023 0.0073 0.0064
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Loa Loa (eye worm) matrixin family protein 0.0597 0.501 1
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0207 0.0198
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.1073 0.1065
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0038 0.0207 0.0198
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.02 0.0751
Brugia malayi MH1 domain containing protein 0.0015 0.0012 0.0005
Echinococcus multilocularis calcium activated potassium channel 0.0038 0.0207 0.0198
Echinococcus multilocularis conserved hypothetical protein 0.0038 0.0207 0.0198
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0038 0.0207 0.0198
Plasmodium falciparum phd finger protein, putative 0.0017 0.0028 0.0072
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0173 0.056
Brugia malayi latrophilin 2 splice variant baaae 0.0042 0.024 0.0461
Trypanosoma brucei hypothetical protein, conserved 0.0086 0.0616 0.2386
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0207 0.0198
Trichomonas vaginalis ap endonuclease, putative 0.0025 0.0097 0.0319
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0038 0.0207 0.0198
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0475 0.1876
Echinococcus granulosus jumonji domain containing protein 0.0024 0.0086 0.0077
Trichomonas vaginalis D-aminoacylase, putative 0.0086 0.0616 0.2366
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Echinococcus granulosus sodium leak channel non selective protein 0.0038 0.0207 0.0198
Onchocerca volvulus 0.0247 0.2001 0.4351
Onchocerca volvulus 0.0026 0.0106 0.0208
Brugia malayi Calcitonin receptor-like protein seb-1 0.0061 0.0406 0.0794
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0016 0.0016 0.0022
Brugia malayi voltage-dependent calcium channel 0.0038 0.0207 0.0395
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0127 0.0967 1
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Leishmania major ATP-dependent phosphofructokinase 0.0127 0.0967 0.3765
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0475 0.0466
Loa Loa (eye worm) PHD-finger family protein 0.0017 0.0028 0.0055
Entamoeba histolytica histone deacetylase, putative 0.0311 0.2553 1
Brugia malayi histone deacetylase 1 (HD1) 0.0311 0.2553 0.5086
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0038 0.0207 0.0412
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0038 0.0207 0.0198
Echinococcus granulosus 6 phosphofructokinase 0.0127 0.0967 0.0959
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0037 0.02 0.0751
Loa Loa (eye worm) Smad1 0.0015 0.0012 0.0024
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0038 0.0207 0.0198
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0026 0.0106 0.0356
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0038 0.0207 0.0198
Toxoplasma gondii histone deacetylase HDAC3 0.0311 0.2553 0.8675
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0021 0.0057 0.0048
Schistosoma mansoni hypothetical protein 0.0019 0.0046 0.0037
Trypanosoma cruzi transcription factor btf3, putative 0.0023 0.0073 0.0252
Mycobacterium tuberculosis Probable lipase LipE 0.0086 0.0616 0.1314
Schistosoma mansoni polycystin 1-related 0.006 0.0394 0.0385
Echinococcus granulosus lamin dm0 0.0015 0.0011 0.0002
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0967 0.193
Leishmania major hypothetical protein, conserved 0.0038 0.0207 0.0776
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0173 0.0622
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0207 0.0198
Onchocerca volvulus Matrilysin homolog 0.0247 0.2001 0.4351
Brugia malayi MH1 domain containing protein 0.0015 0.0012 0.0005
Schistosoma mansoni histone deacetylase hda2 0.0239 0.1931 0.1923
Echinococcus granulosus Smad4 0.0015 0.0012 0.0003
Echinococcus multilocularis aldo keto reductase 0.0026 0.0106 0.0097
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0025 0.0097 0.0343
Brugia malayi phosphofructokinase 0.0127 0.0967 0.1915
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Schistosoma mansoni hypothetical protein 0.0019 0.0046 0.0037
Schistosoma mansoni DNA polymerase eta 0.0071 0.0494 0.0485
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.1073 0.1065
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0025 0.0097 0.0343
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0207 0.0198
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.02 0.0751
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0115 0.0868 0.2929
Echinococcus multilocularis jumonji domain containing protein 0.0024 0.0086 0.0077
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0022
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0301 0.2464 0.4909
Entamoeba histolytica aldose reductase, putative 0.0026 0.0106 0.0356
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0101 0.0359
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0207 0.0198
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0173 0.1658
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.017 0.1341 0.1333
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0025 0.0097 0.0319
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0207 0.0753
Schistosoma mansoni hypothetical protein 0.0019 0.0046 0.0037
Trichomonas vaginalis fk506-binding protein, putative 0.0115 0.0868 0.336
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0311 0.2553 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0026 0.0106 0.0356
Schistosoma mansoni histone deacetylase 0.0311 0.2553 0.2546
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0207 0.0198
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0127 0.0967 0.2082
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Echinococcus multilocularis histone deacetylase 6 0.0231 0.1867 0.1859
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0073 0.0227
Schistosoma mansoni hypothetical protein 0.0625 0.5251 0.5247
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0101 0.0359
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0207 0.0198
Echinococcus granulosus two pore calcium channel protein 2 0.0038 0.0207 0.0198
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0202 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Schistosoma mansoni intermediate filament proteins 0.0015 0.0011 0.0002
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.02 0.0191
Trypanosoma brucei histone deacetylase, putative 0.0231 0.1867 0.7304
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0086 0.0616 0.2452
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0046 0.0092
Toxoplasma gondii transporter, cation channel family protein 0.0038 0.0207 0.0673
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0115 0.0868 0.8961
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0304 0.1136
Treponema pallidum exodeoxyribonuclease (exoA) 0.0025 0.0097 0.085
Loa Loa (eye worm) hypothetical protein 0.0026 0.0106 0.0212
Loa Loa (eye worm) oxidoreductase 0.0026 0.0106 0.0212
Schistosoma mansoni fk506 binding protein 0.0016 0.0016 0.0006
Schistosoma mansoni transient receptor potential channel 0.0038 0.0207 0.0198
Echinococcus granulosus chromobox protein 1 0.0049 0.0304 0.0295
Brugia malayi Matrixin family protein 0.0247 0.2001 0.3984
Echinococcus granulosus beta LACTamase domain containing family member 0.0086 0.0616 0.0607
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0115 0.0868 0.3376
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Toxoplasma gondii exonuclease III APE 0.0025 0.0097 0.0297
Loa Loa (eye worm) oxidoreductase 0.0026 0.0106 0.0212
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0207 0.0198
Brugia malayi cation channel family protein 0.0038 0.0207 0.0395
Leishmania major hypothetical protein, conserved 0.0086 0.0616 0.2386
Echinococcus multilocularis histone deacetylase 6 0.0231 0.1867 0.1859
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0025 0.0097 0.0087
Schistosoma mansoni 60S ribosomal protein L21 0.0038 0.0207 0.0198
Toxoplasma gondii PHD-finger domain-containing protein 0.0017 0.0028 0.0063
Loa Loa (eye worm) ryanodine receptor 0.0038 0.0207 0.0412
Schistosoma mansoni ryanodine receptor related 0.0038 0.0207 0.0198
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0038 0.0207 0.0198
Echinococcus multilocularis voltage gated potassium channel 0.0038 0.0207 0.0198
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0967 0.3749
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0038 0.0207 0.0198
Echinococcus multilocularis ubiquitin specific protease 41 0.0021 0.0057 0.0048
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0038 0.0207 0.0198
Schistosoma mansoni pol-related 0.0026 0.0106 0.0097
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0057 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0256 0.2082 0.8145
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Brugia malayi Matrixin family protein 0.0597 0.501 1
Echinococcus multilocularis two pore calcium channel protein 1 0.0038 0.0207 0.0198
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0207 0.0412
Loa Loa (eye worm) hypothetical protein 0.0061 0.0406 0.0811
Brugia malayi Histone deacetylase 1 0.0311 0.2553 0.5086
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0317 0.1051
Loa Loa (eye worm) hypothetical protein 0.0311 0.2553 0.5095
Loa Loa (eye worm) hypothetical protein 0.0086 0.0616 0.123
Schistosoma mansoni bromodomain containing protein 0.0039 0.0219 0.021
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0057 0.0188
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0317 0.1189
Toxoplasma gondii aldose reductase, putative 0.0026 0.0106 0.033
Echinococcus multilocularis histone deacetylase 3 0.0311 0.2553 0.2546
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0086 0.0616 0.0607
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0898 0.7594 0.7592
Loa Loa (eye worm) hypothetical protein 0.0301 0.2464 0.4918
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0012 0.0024
Loa Loa (eye worm) histone deacetylase 7A 0.0231 0.1867 0.3726
Echinococcus multilocularis ryanodine receptor 44f 0.0038 0.0207 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0016 0.0025
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0207 0.0198
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.02 0.0191
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0038 0.0207 0.0198
Echinococcus granulosus ryanodine receptor 44f 0.0038 0.0207 0.0198
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.02 0.0727
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0207 0.0198
Mycobacterium tuberculosis Probable hydrolase 0.0086 0.0616 0.1314
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0046 0.0037
Loa Loa (eye worm) ion channel NompC 0.0038 0.0207 0.0412
Toxoplasma gondii hypothetical protein 0.0038 0.0207 0.0673
Echinococcus granulosus aldo keto reductase 0.0026 0.0106 0.0097
Loa Loa (eye worm) histone deacetylase 0.0231 0.1867 0.3726
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0038 0.0207 0.0395
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0061 0.0406 0.0794
Echinococcus granulosus intermediate filament protein 0.0015 0.0011 0.0002
Echinococcus granulosus FK506 binding protein 2 0.0016 0.0016 0.0006
Leishmania major histone deacetylase, putative 0.0311 0.2553 1
Brugia malayi jmjC domain containing protein 0.0022 0.0068 0.0117
Echinococcus granulosus potassium large conductance calcium activated 0.0038 0.0207 0.0198
Plasmodium vivax histone deacetylase 2, putative 0.0231 0.1867 0.6336
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.02 0.0727
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0207 0.0198
Schistosoma mansoni jumonji domain containing protein 0.0045 0.0265 0.0256
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0967 0.3749
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0207 0.0198
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0038 0.0207 0.0198
Loa Loa (eye worm) oxidoreductase 0.0026 0.0106 0.0212
Schistosoma mansoni voltage-gated cation channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0055
Echinococcus multilocularis lamin dm0 0.0015 0.0011 0.0002
Trypanosoma cruzi histone deacetylase, putative 0.0231 0.1867 0.7304
Schistosoma mansoni chromobox protein 0.0049 0.0304 0.0295
Echinococcus multilocularis aldo keto reductase 0.0026 0.0106 0.0097
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0099 0.0732 0.0723
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trypanosoma cruzi aldo-keto reductase 0.0026 0.0106 0.038
Schistosoma mansoni histone deacetylase 4 5 0.0231 0.1867 0.1859
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0475 0.1876
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.1073 0.1065
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0021 0.0057 0.0048
Schistosoma mansoni aldo-keto reductase 0.0026 0.0106 0.0097
Loa Loa (eye worm) hypothetical protein 0.0086 0.0616 0.123
Brugia malayi beta-lactamase family protein 0.0086 0.0616 0.1213
Onchocerca volvulus 0.0026 0.0106 0.0208
Leishmania major basic transcription factor 3a, putative 0.0023 0.0073 0.0252
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0967 0.3749
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0071 0.0494 0.0986
Loa Loa (eye worm) hypothetical protein 0.0146 0.1136 0.2268
Loa Loa (eye worm) hypothetical protein 0.0099 0.0732 0.1461
Toxoplasma gondii transporter, cation channel family protein 0.0038 0.0207 0.0673
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.1073 0.1065
Loa Loa (eye worm) histone deacetylase 3 0.0311 0.2553 0.5095
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0127 0.0967 0.3885
Trichomonas vaginalis D-aminoacylase, putative 0.0086 0.0616 0.2366
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0234
Loa Loa (eye worm) beta-lactamase 0.0086 0.0616 0.123
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.02 0.0751
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0021 0.0057 0.0048
Leishmania major prostaglandin f synthase, putative 0.0026 0.0106 0.038
Echinococcus multilocularis short transient receptor potential channel 6 0.0038 0.0207 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0117 0.0401
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0026 0.0106 0.0356
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0019
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0038 0.0207 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0115 0.0868 0.3376
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0115 0.0868 0.3376
Echinococcus multilocularis hyperpolarization activated cyclic 0.0038 0.0207 0.0198
Loa Loa (eye worm) histone deacetylase 11 0.0356 0.2941 0.587
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0038 0.0207 0.0198
Brugia malayi Intermediate filament tail domain containing protein 0.0015 0.0011 0.0003
Echinococcus granulosus voltage gated hydrogen channel 1 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trichomonas vaginalis aldo/keto reductase, putative 0.0026 0.0106 0.0356
Giardia lamblia PHD finger protein 15 0.0017 0.0028 0.0047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0046 0.0092
Loa Loa (eye worm) hypothetical protein 0.0086 0.0616 0.123
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0038 0.0207 0.0198
Echinococcus multilocularis voltage gated potassium channel 0.0038 0.0207 0.0198
Leishmania major histone deacetylase, putative 0.0231 0.1867 0.7304
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0115 0.0868 0.3376
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0038 0.0207 0.0198
Echinococcus granulosus aldo keto reductase 0.0026 0.0106 0.0097
Brugia malayi exodeoxyribonuclease III family protein 0.0025 0.0097 0.0174
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0038 0.0207 0.0395
Brugia malayi beta-lactamase family protein 0.0086 0.0616 0.1213
Loa Loa (eye worm) matrix metalloproteinase 0.0247 0.2001 0.3995
Echinococcus multilocularis 6 phosphofructokinase 0.0127 0.0967 0.0959
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Schistosoma mansoni two-pore calcium channel 0.0038 0.0207 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Brugia malayi Hemopexin family protein 0.035 0.2888 0.5757
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0038 0.0207 0.0198
Schistosoma mansoni immunophilin 0.0115 0.0868 0.086
Loa Loa (eye worm) FKBP5 protein 0.0115 0.0868 0.1733
Leishmania major hypothetical protein, unknown function 0.0038 0.0207 0.0776
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Onchocerca volvulus 0.0086 0.0616 0.1323
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0086 0.0616 0.1314
Trypanosoma brucei unspecified product 0.0026 0.0101 0.0359
Trypanosoma cruzi hypothetical protein, conserved 0.0086 0.0616 0.2386
Echinococcus granulosus histone deacetylase 6 0.0231 0.1867 0.1859
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0128
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.02 0.04
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0016 0.0016 0.0006
Leishmania major fk506-binding protein 1-like protein 0.0115 0.0868 0.3376
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0057 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0127
Schistosoma mansoni aldo-keto reductase 0.0026 0.0106 0.0097
Toxoplasma gondii hypothetical protein 0.0038 0.0207 0.0673
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0038 0.0207 0.0198
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0038 0.0207 0.0198
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0086 0.0616 0.1213
Schistosoma mansoni voltage-dependent calcium channel 0.0038 0.0207 0.0198
Onchocerca volvulus 0.0022 0.0066 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.017 0.1341 0.1333
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0025 0.0097 0.0319
Echinococcus multilocularis 0.0016 0.0016 0.0006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.1073 0.2142
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0025 0.0097 0.0343
Trypanosoma brucei prostaglandin f synthase 0.0026 0.0106 0.038
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0021 0.0057 0.0048
Echinococcus granulosus two pore calcium channel protein 1 0.0038 0.0207 0.0198
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0021 0.0057 0.0048
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0115 0.0868 0.336
Brugia malayi Histone deacetylase family protein 0.0231 0.1867 0.3715
Trypanosoma cruzi transcription factor btf3, putative 0.0023 0.0073 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0117 0.0401
Schistosoma mansoni histone deacetylase 4 5 0.0231 0.1867 0.1859
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0475 0.1831
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.02 0.0191
Schistosoma mansoni jumonji/arid domain-containing protein 0.0022 0.0068 0.0059
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0115 0.0868 0.1717
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0127 0.0967 0.3765
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.027 0.1004
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0115 0.0868 0.1717
Mycobacterium ulcerans lipase LipD 0.0086 0.0616 0.2452
Trypanosoma brucei aldo-keto reductase, putative 0.0026 0.0106 0.038
Mycobacterium leprae conserved hypothetical protein 0.0086 0.0616 0.2452
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0021 0.0057 0.0164
Echinococcus granulosus histone deacetylase 3 0.0311 0.2553 0.2546
Trypanosoma cruzi histone deacetylase, putative 0.0231 0.1867 0.7304
Echinococcus multilocularis lysine specific demethylase 5A 0.0021 0.0059 0.005
Toxoplasma gondii histone deacetylase HDAC5 0.0146 0.1136 0.3843
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Onchocerca volvulus 0.0094 0.0686 0.1477
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trypanosoma brucei histone deacetylase 2 0.0146 0.1136 0.443
Echinococcus multilocularis aldehyde reductase 0.0019 0.004 0.0031
Trypanosoma cruzi DNA polymerase eta, putative 0.0071 0.0494 0.1905
Schistosoma mansoni hypothetical protein 0.0042 0.024 0.0231
Loa Loa (eye worm) oxidoreductase 0.0026 0.0106 0.0212
Loa Loa (eye worm) phosphofructokinase 0.0127 0.0967 0.193
Plasmodium vivax histone deacetylase, putative 0.0231 0.1867 0.6336
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0115 0.0868 0.3376
Brugia malayi ion channel NompC 0.0038 0.0207 0.0395
Loa Loa (eye worm) matrixin family protein 0.0548 0.4585 0.9153
Loa Loa (eye worm) voltage-gated potassium channel 0.0038 0.0207 0.0412
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0061 0.0406 0.0811
Echinococcus multilocularis lamin 0.0015 0.0011 0.0002
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0247 0.2001 0.3995
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0046 0.0037
Brugia malayi Matrixin family protein 0.0247 0.2001 0.3984
Loa Loa (eye worm) hypothetical protein 0.004 0.0219 0.0438
Schistosoma mansoni smad 0.0015 0.0012 0.0003
Brugia malayi Histone deacetylase family protein 0.0231 0.1867 0.3715
Onchocerca volvulus 0.035 0.2888 0.6289
Schistosoma mansoni smad1 5 8 and 0.0015 0.0012 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0967 0.3749
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0207 0.0198
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0207 0.0198
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0038 0.0207 0.0198
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0016 0.0022
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0207 0.0198
Trichomonas vaginalis aldo/keto reductase, putative 0.0026 0.0106 0.0356
Leishmania major DNA polymerase kappa, putative 0.0037 0.02 0.0751
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0038 0.0207 0.0428
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0038 0.0207 0.0198
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0115 0.0868 0.086
Brugia malayi cation channel family protein 0.0038 0.0207 0.0395
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0037 0.02 0.0404
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0115 0.0868 0.086
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0173 0.0622
Mycobacterium ulcerans hydrolase 0.0301 0.2464 1
Brugia malayi Smad1 0.0015 0.0012 0.0005
Brugia malayi histone deacetylase 3 (HD3) 0.0311 0.2553 0.5086
Brugia malayi 6-phosphofructokinase 0.0127 0.0967 0.1915
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0025 0.0097 0.0297
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0021 0.0057 0.0048
Brugia malayi MH2 domain containing protein 0.0015 0.0012 0.0005
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0016 0.0016 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Echinococcus granulosus dna polymerase kappa 0.0037 0.02 0.0191
Entamoeba histolytica transcription factor BTF3, putative 0.0023 0.0073 0.0227
Schistosoma mansoni calcium-activated potassium channel 0.0038 0.0207 0.0198
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0967 0.3749
Onchocerca volvulus Matrix metalloproteinase homolog 0.0548 0.4585 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0057 0.0164
Mycobacterium leprae Probable lipase LipE 0.0086 0.0616 0.2452
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0207 0.0198
Echinococcus multilocularis mothers against decapentaplegic 5 0.0015 0.0012 0.0003
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0038 0.0207 0.0198
Brugia malayi chromobox protein homolog 3 0.0028 0.0117 0.0216
Echinococcus multilocularis sodium leak channel non selective protein 0.0038 0.0207 0.0198
Echinococcus multilocularis histone deacetylase 0.0231 0.1867 0.1859
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0207 0.0198
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0681 0.5729 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0475 0.0466
Schistosoma mansoni transient receptor potential channel 0.0038 0.0207 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0025 0.0097 0.033
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0207 0.0198
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Echinococcus granulosus potassium voltage gated channel protein 0.0038 0.0207 0.0198
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0173 0.0622
Schistosoma mansoni hypothetical protein 0.0019 0.0046 0.0037
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.02 0.0751
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0038 0.0207 0.0395
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Leishmania major histone deacetylase, putative 0.0231 0.1867 0.7304
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0273 0.1036
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0207 0.0673
Schistosoma mansoni vesicular amine transporter 0.0038 0.0207 0.0198
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0301 0.2464 0.5359
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trichomonas vaginalis aldo/keto reductase, putative 0.0026 0.0106 0.0356
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0173 0.056
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0115 0.0868 0.336
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0333 0.2739 0.2732
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0038 0.0207 0.0395
Loa Loa (eye worm) hypothetical protein 0.0247 0.2001 0.3995
Brugia malayi Heterochromatin protein 1 0.0049 0.0304 0.0589
Loa Loa (eye worm) hypothetical protein 0.021 0.1684 0.3362
Schistosoma mansoni hypothetical protein 0.035 0.2888 0.2882
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0015 0.0012 0.0003
Giardia lamblia Aldose reductase 0.0026 0.0106 0.0356
Echinococcus multilocularis transient receptor potential cation channel 0.0038 0.0207 0.0198
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Echinococcus multilocularis voltage dependent calcium channel 0.0038 0.0207 0.0198
Trichomonas vaginalis histone deacetylase, putative 0.0311 0.2553 1
Brugia malayi Bromodomain containing protein 0.0023 0.0075 0.0131
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0038 0.0207 0.0776
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.002 0.0052 0.0043
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0026 0.0106 0.038
Mycobacterium leprae PROBABLE HYDROLASE 0.0301 0.2464 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0164 0.1289 0.1281
Echinococcus granulosus hyperpolarization activated cyclic 0.0038 0.0207 0.0198
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0038 0.0207 0.0198
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.1073 0.1065
Echinococcus multilocularis transcription factor btf3 0.0023 0.0073 0.0064
Loa Loa (eye worm) intermediate filament protein 0.0015 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0086 0.0616 0.123
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0898 0.7594 0.7592
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0038 0.0207 0.0395
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0038 0.0207 0.0198
Schistosoma mansoni hypothetical protein 0.0625 0.5251 0.5247
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0173 0.0622
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0031
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Trypanosoma brucei transcription factor BTF3, putative 0.0023 0.0073 0.0252
Brugia malayi 6-phosphofructokinase 0.0127 0.0967 0.1915
Mycobacterium ulcerans esterase/lipase LipP 0.0086 0.0616 0.2452
Echinococcus granulosus smad 0.0015 0.0012 0.0003
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0016 0.0016 0.0025
Schistosoma mansoni transient receptor potential channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0094 0.0686 0.137
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trichomonas vaginalis penicillin-binding protein, putative 0.0086 0.0616 0.2366
Loa Loa (eye worm) voltage-gated calcium channel 0.0038 0.0207 0.0412
Schistosoma mansoni immunophilin 0.0115 0.0868 0.086
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0038 0.0207 0.0395
Trypanosoma cruzi histone deacetylase, putative 0.0231 0.1867 0.7304
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0057 0.0164
Echinococcus multilocularis histone deacetylase 1 0.0311 0.2553 0.2546
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0046 0.0074
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0046 0.0074
Loa Loa (eye worm) calcium channel 0.0038 0.0207 0.0412
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0475 0.0466
Trichomonas vaginalis histone deacetylase, putative 0.0311 0.2553 1
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0173 0.0622
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0038 0.0207 0.0198
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0025 0.0097 0.0141
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0173 0.0622
Echinococcus multilocularis potassium voltage gated channel protein 0.0038 0.0207 0.0198
Onchocerca volvulus 0.0026 0.0106 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0127
Leishmania major aldo-keto reductase-like protein 0.0026 0.0106 0.038
Echinococcus multilocularis chromobox protein 1 0.0049 0.0304 0.0295
Schistosoma mansoni chromobox protein 0.0049 0.0304 0.0295
Loa Loa (eye worm) hypothetical protein 0.0247 0.2001 0.3995
Echinococcus multilocularis Smad4 0.0015 0.0012 0.0003
Toxoplasma gondii NAC domain-containing protein 0.0023 0.0073 0.0218
Loa Loa (eye worm) histone deacetylase 1 0.0311 0.2553 0.5095
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Onchocerca volvulus 0.0026 0.0106 0.0208
Trichomonas vaginalis phosphofructokinase, putative 0.0127 0.0967 0.3749
Trypanosoma brucei unspecified product 0.0037 0.02 0.0751
Echinococcus granulosus TGF beta signal transducer SmadC 0.0015 0.0012 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0038 0.0207 0.0198
Echinococcus granulosus lamin 0.0015 0.0011 0.0002
Loa Loa (eye worm) ICD-1 protein 0.0023 0.0073 0.0146
Echinococcus granulosus PHD finger protein rhinoceros 0.0017 0.0028 0.0019
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0025 0.0097 0.0087
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0476 0.3971 0.3965
Echinococcus multilocularis sodium channel protein 0.0038 0.0207 0.0198
Echinococcus multilocularis GPCR, family 2 0.0019 0.0046 0.0037
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0086 0.0616 0.0607
Echinococcus multilocularis hyperpolarization activated cyclic 0.0038 0.0207 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Schistosoma mansoni histone deacetylase hda2 0.0146 0.1136 0.1128
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.02 0.0751
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0017
Toxoplasma gondii histone deacetylase HDAC1 0.0231 0.1867 0.6336
Echinococcus granulosus shaker cognate 0.0038 0.0207 0.0198
Loa Loa (eye worm) heterochromatin protein 1 0.0049 0.0304 0.0607
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Echinococcus granulosus transcription factor btf3 0.0023 0.0073 0.0064
Echinococcus granulosus transient receptor potential cation channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Loa Loa (eye worm) transcription factor SMAD2 0.0226 0.1821 0.3634
Plasmodium vivax histone deacetylase, putative 0.0356 0.2941 1
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0475 0.1588
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0207 0.0198
Echinococcus multilocularis transient receptor potential gamma protein 0.0038 0.0207 0.0198
Schistosoma mansoni hypothetical protein 0.0038 0.0207 0.0198
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0547 0.4584 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0057 0.0164
Plasmodium vivax basic transcription factor 3b, putative 0.0023 0.0073 0.0218
Giardia lamblia Histone deacetylase 0.0311 0.2553 1
Echinococcus granulosus dna polymerase eta 0.0071 0.0494 0.0485
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0016 0.0016 0.0013
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0046 0.0037
Brugia malayi Transient-receptor-potential like protein 0.0038 0.0207 0.0395
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0038 0.0207 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.027 0.1027
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0101 0.0359
Mycobacterium tuberculosis Probable lipase LipD 0.0086 0.0616 0.1314
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0115 0.0868 0.336
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Onchocerca volvulus Matrilysin homolog 0.0548 0.4585 1
Mycobacterium tuberculosis Conserved protein 0.0086 0.0616 0.1314
Trypanosoma brucei DNA polymerase eta, putative 0.0071 0.0494 0.1905
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0317 0.0308
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0026 0.0106 0.0369
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0247 0.2001 0.1994
Toxoplasma gondii transporter, cation channel family protein 0.0038 0.0207 0.0673
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Echinococcus granulosus hypothetical protein 0.0038 0.0207 0.0198
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0311 0.2553 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Echinococcus multilocularis microtubule associated protein 2 0.1178 1 1
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0038 0.0207 0.0395
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0106 0.0198
Schistosoma mansoni ap endonuclease 0.0025 0.0097 0.0087
Echinococcus granulosus voltage gated potassium channel 0.0038 0.0207 0.0198
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0016 0.0016 0.0006
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Mycobacterium ulcerans oxidoreductase 0.0026 0.0106 0.0369
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0016 0.0025
Schistosoma mansoni voltage-gated ion channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0294 0.2409 0.4808
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0038 0.0207 0.0395
Plasmodium falciparum histone deacetylase, putative 0.0231 0.1867 0.7304
Echinococcus multilocularis PHD finger protein rhinoceros 0.0017 0.0028 0.0019
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0204 0.1632 0.1625
Plasmodium falciparum histone deacetylase 2 0.0231 0.1867 0.7304
Echinococcus multilocularis histone deacetylase 8 0.0146 0.1136 0.1128
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0026 0.0106 0.038
Mycobacterium tuberculosis Conserved protein 0.0086 0.0616 0.1314
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0038 0.0207 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Schistosoma mansoni histone deacetylase 0.0311 0.2553 0.2546
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0038 0.0207 0.0198
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0207 0.0753
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0311 0.2553 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.02 0.0751
Loa Loa (eye worm) voltage-gated potassium channel 0.0038 0.0207 0.0412
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0173 0.056
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0038 0.0207 0.0198
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0016 0.0016 0.0022
Echinococcus granulosus aldehyde reductase 0.0019 0.004 0.0031
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Giardia lamblia Aldose reductase 0.0026 0.0106 0.0356
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0038 0.0207 0.0198
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0056 0.0365 0.0356
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0317 0.1051
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0038 0.0207 0.0198
Brugia malayi beta-NAC-like protein 0.0023 0.0073 0.0128
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0132
Schistosoma mansoni jumonji/arid domain-containing protein 0.0022 0.0068 0.0059
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.02 0.0382
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.02 0.0404
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0026 0.0106 0.0097
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.02 0.0754
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.02 0.0191
Schistosoma mansoni lamin 0.0015 0.0011 0.0002
Toxoplasma gondii ABC1 family protein 0.0086 0.0616 0.207
Trichomonas vaginalis chromobox protein, putative 0.003 0.0135 0.0472
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.02 0.0751
Echinococcus multilocularis beta LACTamase domain containing family member 0.0086 0.0616 0.0607
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0038 0.0207 0.0776
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0016 0.0016 0.0022
Schistosoma mansoni smad1 5 8 and 0.0015 0.0012 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0304 0.1136
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0475 0.1005
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.02 0.0727
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0073 0.0227
Echinococcus granulosus geminin 0.0625 0.5251 0.5247
Onchocerca volvulus 0.0016 0.0016 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0086 0.0616 0.2366
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0046 0.0037
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0038 0.0207 0.0198
Trypanosoma brucei histone deacetylase 1 0.0311 0.2553 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0026 0.0106 0.0193
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0026 0.0106 0.0097
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0038 0.0207 0.0198
Schistosoma mansoni hypothetical protein 0.0016 0.0016 0.0006
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0173 1
Trypanosoma cruzi hypothetical protein, conserved 0.0086 0.0616 0.2386
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0016 0.0016 0.0013
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0038 0.0207 0.0395
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.1073 0.1065
Trypanosoma brucei unspecified product 0.0026 0.0101 0.0359
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0207 0.0198
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0099 0.0732 0.0723
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0056 0.0365 0.0356
Entamoeba histolytica hypothetical protein 0.0023 0.0073 0.0227
Loa Loa (eye worm) hypothetical protein 0.0086 0.0616 0.123
Trichomonas vaginalis chromobox protein, putative 0.003 0.0135 0.0472
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0333 0.2739 0.2732
Loa Loa (eye worm) acetyltransferase 0.017 0.1341 0.2676
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0317 0.1189
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0016 0.0016 0.0025
Echinococcus multilocularis dna polymerase eta 0.0071 0.0494 0.0485
Onchocerca volvulus Alhambra homolog 0.0017 0.0028 0.0037
Echinococcus granulosus voltage gated potassium channel 0.0038 0.0207 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Entamoeba histolytica phosphofructokinase, putative 0.0127 0.0967 0.3749
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Echinococcus granulosus lysine specific demethylase 5A 0.0022 0.0068 0.0059
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0086 0.0616 0.1314
Brugia malayi PHD-finger family protein 0.0018 0.0035 0.0051
Brugia malayi Matrixin family protein 0.0247 0.2001 0.3984
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0038 0.0207 0.0198
Echinococcus multilocularis fk506 binding protein 0.0115 0.0868 0.086
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0038 0.0207 0.0198
Entamoeba histolytica aldose reductase, putative 0.0026 0.0106 0.0356
Loa Loa (eye worm) hypothetical protein 0.0021 0.0057 0.0114
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0038 0.0207 0.0395
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0185 0.037
Schistosoma mansoni microtubule-associated protein tau 0.1178 1 1
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.02 0.0754
Echinococcus granulosus hypothetical protein 0.0026 0.0106 0.0097
Loa Loa (eye worm) voltage-dependent calcium channel 0.0038 0.0207 0.0412
Plasmodium falciparum histone deacetylase 1 0.0311 0.2553 1
Echinococcus multilocularis musashi 0.0015 0.0011 0.0002
Leishmania major DNA polymerase eta, putative 0.0046 0.0273 0.1036
Trypanosoma cruzi histone deacetylase 1, putative 0.0311 0.2553 1
Mycobacterium tuberculosis Probable esterase LipL 0.0086 0.0616 0.1314
Mycobacterium tuberculosis Conserved protein 0.0086 0.0616 0.1314
Echinococcus multilocularis voltage dependent calcium channel 0.0038 0.0207 0.0198
Echinococcus multilocularis chromobox protein 1 0.0049 0.0304 0.0295
Leishmania major peptidylprolyl isomerase-like protein 0.0115 0.0868 0.3376
Brugia malayi PHD-finger family protein 0.0017 0.0028 0.0037
Trypanosoma cruzi histone deacetylase, putative 0.0146 0.1136 0.443
Trichomonas vaginalis aldo-keto reductase, putative 0.0026 0.0106 0.0356
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0173 0.0645
Echinococcus granulosus short transient receptor potential channel 6 0.0038 0.0207 0.0198
Brugia malayi MH2 domain containing protein 0.0226 0.1821 0.3622
Trichomonas vaginalis histone deacetylase, putative 0.0311 0.2553 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.1073 0.2127
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0038 0.0207 0.0673
Trypanosoma cruzi aldo/keto reductase, putative 0.0026 0.0106 0.038
Echinococcus granulosus histone deacetylase 0.0231 0.1867 0.1859
Brugia malayi histone deacetylase 11 0.0356 0.2941 0.5863
Echinococcus multilocularis geminin 0.0625 0.5251 0.5247
Brugia malayi MH2 domain containing protein 0.0015 0.0012 0.0005
Trypanosoma brucei histone deacetylase 3 0.0231 0.1867 0.7304
Echinococcus granulosus voltage dependent calcium channel 0.0038 0.0207 0.0198
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0115 0.0868 0.1733
Echinococcus multilocularis histone deacetylase 6 0.0239 0.1931 0.1923
Brugia malayi intermediate filament protein 0.0015 0.0011 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0173 0.0622
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0016 0.0016 0.0031
Brugia malayi Matrixin family protein 0.0247 0.2001 0.3984
Echinococcus granulosus histone deacetylase 1 0.0311 0.2553 0.2546
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0294 0.2409 0.4799
Echinococcus granulosus GPCR family 2 0.0019 0.0046 0.0037
Loa Loa (eye worm) hypothetical protein 0.0085 0.061 0.1218
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0017 0.0028 0.0019
Schistosoma mansoni ap endonuclease 0.0025 0.0097 0.0087
Plasmodium vivax hypothetical protein, conserved 0.0086 0.0616 0.207
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0412
Loa Loa (eye worm) 6-phosphofructokinase 0.0127 0.0967 0.193
Echinococcus granulosus TRP transient receptor potential channel 0.0038 0.0207 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0207 0.0198
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0115 0.0868 0.3482
Loa Loa (eye worm) hypothetical protein 0.0086 0.0616 0.123
Brugia malayi acetyltransferase, GNAT family protein 0.017 0.1341 0.2662
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0115 0.0868 0.336
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.02 0.0751

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 75 nM Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis ChEMBL. 24345446
IC50 (binding) = 1410 nM Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis ChEMBL. 24345446
IC50 (binding) = 1790 nM Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis ChEMBL. 24345446
IC50 (binding) = 2630 nM Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis ChEMBL. 24345446
IC50 (binding) = 3330 nM Inhibition of human HDAC3/NCOR2 using RHKK(Ac) as substrate by fluorimetric analysis ChEMBL. 24345446
IC50 (binding) = 4390 nM Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis ChEMBL. 24345446
IC50 (binding) = 4890 nM Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis ChEMBL. 24345446

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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