Detailed information for compound 309680

Basic information

Technical information
  • TDR Targets ID: 309680
  • Name: 5-[(4-phenylphenyl)sulfonylmethyl]-2H-tetrazo le
  • MW: 300.336 | Formula: C14H12N4O2S
  • H donors: 1 H acceptors: 5 LogP: 1.94 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=S(=O)(c1ccc(cc1)c1ccccc1)Cc1nnn[nH]1
  • InChi: 1S/C14H12N4O2S/c19-21(20,10-14-15-17-18-16-14)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9H,10H2,(H,15,16,17,18)
  • InChiKey: PYOONQJWYOQSLT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[(4-phenylphenyl)sulfonylmethyl]-2H-1,2,3,4-tetrazole
  • 1H-Tetrazole, 5-[([1,1'-biphenyl]-4-ylsulfonyl)methyl]-
  • AIDS-191213
  • AIDS191213

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tumor protein p63 0.0383 0.3482 0.3481
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1404 0.2772
Brugia malayi Dopamine receptor protein 2 0.0037 0.0192 0.0306
Brugia malayi photoreceptor-specific nuclear receptor 0.0249 0.221 0.3524
Schistosoma mansoni hypothetical protein 0.004 0.0222 0.0305
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0111 0.0897 0.1703
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0042 0.0145
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0111 0.0897 0.4244
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.0247 0.0246
Brugia malayi beta-lactamase family protein 0.0035 0.0179 0.0284
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Onchocerca volvulus 0.0037 0.0192 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0249 0.221 0.3524
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0194 0.169 0.1689
Echinococcus granulosus transient receptor potential gamma protein 0.0033 0.0159 0.0158
Plasmodium vivax SET domain protein, putative 0.0064 0.0448 0.6637
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0033 0.0159 0.0194
Plasmodium vivax potassium channel, putative 0.0024 0.0075 0.1
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0192 0.0191
Schistosoma mansoni inositol monophosphatase 0.0111 0.0897 0.1233
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0033 0.0159 0.0158
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0037 0.0192 0.0191
Plasmodium vivax importin-beta 2, putative 0.0028 0.0112 0.1562
Schistosoma mansoni lamin 0.0031 0.0135 0.0185
Plasmodium falciparum potassium channel 0.0024 0.0075 0.1
Brugia malayi Dopamine receptor protein 1 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0132 0.1094 0.1745
Schistosoma mansoni hypothetical protein 0.0024 0.0075 0.0102
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0067 0.0482 0.0951
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Schistosoma mansoni survival motor neuron protein 0.0047 0.0289 0.0396
Trypanosoma brucei Metacaspase-4 0.0043 0.025 0.0945
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.091 0.8478 0.8477
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Brugia malayi Importin beta-1 subunit 0.0028 0.0112 0.0178
Schistosoma mansoni myosin xvIII 0.0037 0.0192 0.0263
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0192 0.0306
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0249 0.221 0.221
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1404 0.2772
Loa Loa (eye worm) DR-78 0.0118 0.0961 0.1531
Giardia lamblia Glycogen phosphorylase 0.055 0.5065 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0037 0.0192 0.0306
Toxoplasma gondii exonuclease III APE 0.006 0.0417 0.1818
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0677 0.6272 0.6272
Brugia malayi ion channel NompC 0.0033 0.0159 0.0252
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Loa Loa (eye worm) transcription factor SMAD2 0.0133 0.1105 0.1761
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0249 0.221 0.221
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.1045 1
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0327 0.052
Loa Loa (eye worm) hypothetical protein 0.0096 0.0752 0.1199
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0628 0.1224
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0159 0.0217
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0628 0.5755
Plasmodium falciparum potassium channel 0.0024 0.0075 0.1
Echinococcus multilocularis lamin 0.0031 0.0135 0.0134
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0024 0.0075 0.0119
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0452 0.1973
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0274
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.016 0.0159
Schistosoma mansoni growth hormone secretagogue receptor 0.0037 0.0192 0.0263
Loa Loa (eye worm) hypothetical protein 0.043 0.392 0.625
Echinococcus multilocularis G-protein coupled receptor, putative 0.0037 0.0192 0.0191
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0179 0.0811
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0925 0.4377
Loa Loa (eye worm) hypothetical protein 0.0132 0.1094 0.1745
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0249 0.221 0.3524
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0179 0.0811
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0602 0.1115
Schistosoma mansoni vesicular amine transporter 0.0033 0.0159 0.0217
Schistosoma mansoni glycogen phosphorylase 0.055 0.5065 0.6965
Brugia malayi G-protein coupled receptor 0.0037 0.0192 0.0306
Onchocerca volvulus 0.0037 0.0192 0.0261
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0284
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0091 0.0145
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0192 0.0191
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0132 0.1094 0.1745
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0172 0.0274
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Schistosoma mansoni hypothetical protein 0.0037 0.0192 0.0263
Onchocerca volvulus 0.0037 0.0192 0.0261
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0076 0.0565 0.0901
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0159 0.0217
Echinococcus multilocularis caspase 0.0113 0.0917 0.0916
Brugia malayi larval opioid receptor 0.0037 0.0192 0.0306
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0037 0.0192 0.0306
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0284 0.0389
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0113 0.0917 0.0916
Brugia malayi PAS domain containing protein 0.0055 0.0368 0.0587
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0118 0.0961 0.096
Onchocerca volvulus 0.0037 0.0192 0.0261
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0037 0.0192 0.0261
Schistosoma mansoni transient receptor potential channel 0.0033 0.0159 0.0217
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0042 0.0247 0.0246
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0091 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0038 0.0074
Plasmodium vivax glutathione reductase, putative 0.005 0.0318 0.4682
Loa Loa (eye worm) inositol-1 0.0111 0.0897 0.143
Echinococcus granulosus 7TM GPCR rhodopsin 0.0037 0.0192 0.0191
Leishmania major hypothetical protein, conserved 0.0024 0.0075 0.0744
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0628 0.0627
Echinococcus granulosus two pore calcium channel protein 2 0.0033 0.0159 0.0158
Loa Loa (eye worm) TWK-7 protein 0.0024 0.0075 0.0119
Onchocerca volvulus 0.0031 0.0135 0.0147
Echinococcus granulosus nuclear factor of activated T cells 5 0.0084 0.0637 0.0637
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Echinococcus granulosus tm gpcr rhodopsin 0.091 0.8478 0.8477
Loa Loa (eye worm) hypothetical protein 0.004 0.0222 0.0354
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0232 0.0318
Schistosoma mansoni voltage-dependent calcium channel 0.0033 0.0159 0.0217
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0091 0.0323
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0192 0.0191
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0038 0.0074
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0024 0.0075 0.0259
Leishmania major cytochrome p450-like protein 0.0026 0.0091 0.093
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0159 0.0158
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0677 0.6272 0.6272
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0125 0.0455
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0033 0.0159 0.0252
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Schistosoma mansoni hypothetical protein 0.0464 0.4247 0.584
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.025 0.1074
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0033 0.0159 0.0252
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Schistosoma mansoni transient receptor potential channel 0.0033 0.0159 0.0217
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.0628 0.6969
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0448 0.0447
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0087 0.067 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Onchocerca volvulus Protein ultraspiracle homolog 0.0249 0.221 0.4294
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0033 0.0159 0.0158
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0249 0.221 0.4294
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0179 0.0353
Echinococcus granulosus flap endonuclease 1 0.003 0.0125 0.0124
Echinococcus multilocularis transfer RNA-Gly 0.0033 0.0159 0.0158
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0033 0.0159 0.0252
Onchocerca volvulus 0.0118 0.0961 0.1797
Echinococcus granulosus g protein coupled receptor 0.0037 0.0192 0.0191
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi Calcitonin receptor-like protein seb-1 0.0161 0.1368 0.218
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0348 0.5131
Loa Loa (eye worm) hypothetical protein 0.0046 0.0283 0.0451
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0348 0.5131
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0448 0.1952
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0473 0.065
Echinococcus granulosus 7tm_1 domain containing protein 0.0037 0.0192 0.0191
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0024 0.0075 0.0259
Loa Loa (eye worm) solute carrier family 6 member 4 0.0096 0.0752 0.1199
Entamoeba histolytica Flap nuclease, putative 0.003 0.0125 0.0166
Mycobacterium ulcerans beta-lactamase 0.0035 0.0179 0.0811
Echinococcus granulosus lysine specific demethylase 6a 0.0034 0.0172 0.0171
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0249 0.221 0.221
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0038 0.0074
Loa Loa (eye worm) hypothetical protein 0.0056 0.0377 0.0601
Echinococcus granulosus potassium channel subfamily K 0.0024 0.0075 0.0074
Brugia malayi hypothetical protein 0.0132 0.1094 0.1745
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0249 0.221 0.221
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0154 0.0245
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0307 0.0488
Schistosoma mansoni hypothetical protein 0.0047 0.0289 0.0396
Echinococcus multilocularis sodium channel protein 0.0065 0.0466 0.0465
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Onchocerca volvulus 0.0037 0.0192 0.0261
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0602 0.0827
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0159 0.0158
Loa Loa (eye worm) uncoordinated protein 58 0.0024 0.0075 0.0119
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0179 0.0284
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0024 0.0075 0.0119
Onchocerca volvulus 0.0056 0.0377 0.063
Echinococcus granulosus lamin 0.0031 0.0135 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.025 0.0494
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0125 0.0455
Loa Loa (eye worm) hypothetical protein 0.003 0.013 0.0206
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.0247 0.0246
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0042 0.0247 0.0246
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0042 0.0494
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0179 0.0811
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0417 0.0665
Echinococcus multilocularis shaker cognate 0.0033 0.0159 0.0158
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Trypanosoma brucei metacaspase MCA2 0.0043 0.025 0.0945
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0159 0.0666
Onchocerca volvulus 0.0118 0.0961 0.1797
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0192 0.0191
Echinococcus multilocularis two pore calcium channel protein 1 0.0033 0.0159 0.0158
Loa Loa (eye worm) steroid hormone receptor 0.0249 0.221 0.3524
Toxoplasma gondii hypothetical protein 0.0221 0.1943 0.8604
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Schistosoma mansoni lamin 0.0031 0.0135 0.0185
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0118 0.0961 0.096
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0024 0.0075 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.025 0.0494
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0033 0.0159 0.0252
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0417 0.1952
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0024 0.0075 0.0074
Mycobacterium ulcerans endonuclease IV 0.0087 0.067 0.3158
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0192 0.0263
Schistosoma mansoni cpg binding protein 0.0034 0.0172 0.0235
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0194 0.169 0.1689
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0024 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Onchocerca volvulus 0.0037 0.0192 0.0261
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.025 0.0945
Brugia malayi Pre-SET motif family protein 0.0439 0.4007 0.6387
Schistosoma mansoni amine GPCR 0.0037 0.0192 0.0263
Schistosoma mansoni hypothetical protein 0.0051 0.0327 0.0448
Schistosoma mansoni hypothetical protein 0.0059 0.0401 0.0551
Schistosoma mansoni hypothetical protein 0.0293 0.2628 0.3613
Chlamydia trachomatis glycogen phosphorylase 0.055 0.5065 1
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0249 0.221 0.3039
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0159 0.0158
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0318 0.4682
Schistosoma mansoni hypothetical protein 0.0051 0.0327 0.0448
Onchocerca volvulus 0.0037 0.0192 0.0261
Echinococcus granulosus TRP transient receptor potential channel 0.0033 0.0159 0.0158
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.2221 0.4385
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Brugia malayi tailless protein 0.0118 0.0961 0.1531
Chlamydia trachomatis endonuclease IV 0.0087 0.067 0.1307
Trypanosoma brucei metacaspase MCA3 0.0043 0.025 0.0945
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0925 0.4377
Echinococcus granulosus ecdysone induced protein 78C 0.0249 0.221 0.221
Loa Loa (eye worm) hypothetical protein 0.0067 0.0477 0.076
Brugia malayi Serotonin receptor 0.0037 0.0192 0.0306
Mycobacterium ulcerans lipase LipD 0.0035 0.0179 0.0811
Echinococcus multilocularis lysine specific demethylase 6a 0.0034 0.0172 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.2221 0.4385
Mycobacterium ulcerans ion transport protein 0.0024 0.0075 0.0316
Leishmania major calcium/potassium channel (CAKC), putative 0.0024 0.0075 0.0744
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0037 0.0192 0.0263
Plasmodium falciparum importin beta, putative 0.0028 0.0112 0.1562
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0024 0.0075 0.0119
Trichomonas vaginalis glycogen phosphorylase, putative 0.055 0.5065 1
Brugia malayi mbt repeat family protein 0.0046 0.0284 0.0452
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0274
Echinococcus granulosus sex peptide receptor 0.0037 0.0192 0.0191
Schistosoma mansoni flap endonuclease-1 0.0027 0.0098 0.0134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.0098
Echinococcus multilocularis ecdysone induced protein 78C 0.0249 0.221 0.221
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0192 0.0263
Echinococcus granulosus neuropeptide receptor 0.0037 0.0192 0.0191
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Brugia malayi nuclear hormone receptor family member odr-7 0.0118 0.0961 0.1531
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0284
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0677 0.6272 0.8625
Loa Loa (eye worm) voltage-dependent calcium channel 0.0254 0.2256 0.3597
Onchocerca volvulus 0.0047 0.0289 0.0453
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.0075 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0037 0.0192 0.0306
Leishmania major hypothetical protein, conserved 0.0034 0.0172 0.1835
Brugia malayi steroid hormone receptor 0.0249 0.221 0.3524
Brugia malayi jmjC domain containing protein 0.0129 0.1071 0.1708
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0159 0.0158
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0439 0.4007 0.6387
Trypanosoma cruzi metacaspase, putative 0.0043 0.025 0.0945
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0102 0.0812 0.1116
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0125 0.0247
Brugia malayi Cytochrome P450 family protein 0.0059 0.0408 0.065
Mycobacterium tuberculosis Conserved protein 0.0035 0.0179 0.0811
Schistosoma mansoni hypothetical protein 0.0037 0.0192 0.0263
Echinococcus granulosus hypothetical protein 0.0033 0.0159 0.0158
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0247 0.0338
Onchocerca volvulus 0.0249 0.221 0.4294
Echinococcus multilocularis potassium channel subfamily K 8 0.0024 0.0075 0.0074
Onchocerca volvulus 0.043 0.392 0.7711
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0318 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Trypanosoma brucei trypanothione reductase 0.005 0.0318 0.1211
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0249 0.221 0.3524
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0024 0.0075 0.0119
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0111 0.0897 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0062 0.0253
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0037 0.0192 0.0191
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis dro:myosuppressin receptor 0.0037 0.0192 0.0191
Brugia malayi hypothetical protein 0.0118 0.0961 0.1531
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0307 0.042
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0628 0.0627
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0344 0.0344
Schistosoma mansoni hypothetical protein 0.0711 0.6587 0.9058
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0192 0.0191
Plasmodium falciparum glutathione reductase 0.005 0.0318 0.4682
Echinococcus granulosus G protein coupled receptor 139 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Loa Loa (eye worm) hypothetical protein 0.0083 0.0628 0.1001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus granulosus orexin receptor type 2 0.0037 0.0192 0.0191
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0677 0.6272 0.8625
Toxoplasma gondii ion channel protein 0.0024 0.0075 0.0294
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0448 0.0614
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Schistosoma mansoni steroid hormone receptor ad4bp 0.0249 0.221 0.3039
Loa Loa (eye worm) hypothetical protein 0.0053 0.0344 0.0549
Plasmodium vivax potassium channel, putative 0.0024 0.0075 0.1
Trichomonas vaginalis set domain proteins, putative 0.0499 0.4581 0.9043
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0033 0.0159 0.0158
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0249 0.221 0.3524
Echinococcus granulosus geminin 0.0711 0.6587 0.6587
Loa Loa (eye worm) jmjC domain-containing protein 0.0131 0.1089 0.1736
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0159 0.0158
Loa Loa (eye worm) hypothetical protein 0.0119 0.0976 0.1555
Schistosoma mansoni hypothetical protein 0.0033 0.0159 0.0217
Brugia malayi Tachykinin-like peptides receptor 99D 0.0037 0.0192 0.0306
Echinococcus granulosus allatostatin A receptor 0.0037 0.0192 0.0191
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0037 0.0192 0.0263
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0076 0.057 0.0783
Echinococcus granulosus calcium activated potassium channel 0.0033 0.0159 0.0158
Schistosoma mansoni neuropeptide f receptor 76f 0.0037 0.0192 0.0263
Schistosoma mansoni ap endonuclease 0.006 0.0417 0.0573
Trypanosoma brucei calcium-activated potassium channel, putative 0.0024 0.0075 0.0259
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.025 0.2221 0.3541
Schistosoma mansoni hypothetical protein 0.0051 0.0327 0.0448
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0042 0.0128
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.0075 0.0102
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0024 0.0075 0.0259
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0075 0.0148
Schistosoma mansoni retinoic acid receptor RXR 0.0249 0.221 0.3039
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0037 0.0192 0.0263
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0417 0.4599
Onchocerca volvulus 0.0037 0.0192 0.0261
Mycobacterium tuberculosis Probable reductase 0.0114 0.0925 0.4377
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0087 0.067 0.6181
Echinococcus granulosus serotonin receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis short transient receptor potential channel 6 0.0033 0.0159 0.0158
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0037 0.0192 0.0191
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0087 0.067 0.1067
Onchocerca volvulus 0.0024 0.0075 0.0026
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0118 0.0961 0.1797
Onchocerca volvulus 0.0024 0.0075 0.0026
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.0247 0.0393
Brugia malayi mbt repeat family protein 0.0046 0.0284 0.0452
Loa Loa (eye worm) hypothetical protein 0.0064 0.0448 0.0713
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0159 0.0158
Loa Loa (eye worm) voltage-gated potassium channel 0.0033 0.0159 0.0252
Trypanosoma cruzi metacaspase, putative 0.0043 0.025 0.0945
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0159 0.0158
Echinococcus multilocularis glycogen phosphorylase 0.055 0.5065 0.5065
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0677 0.6272 0.6272
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0249 0.221 0.3524
Echinococcus multilocularis two pore calcium channel protein 2 0.0033 0.0159 0.0158
Schistosoma mansoni ran 0.0021 0.0042 0.0056
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0034 0.0172 0.0274
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0125 0.0199
Brugia malayi neuropeptide F receptor 0.0037 0.0192 0.0306
Echinococcus multilocularis caspase 8 0.0043 0.025 0.0249
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Echinococcus granulosus inositol monophosphatase 1 0.0111 0.0897 0.0896
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0179 0.0811
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.2021 0.202
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0024 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi MH2 domain containing protein 0.0133 0.1105 0.1761
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0091 0.0323
Brugia malayi hypothetical protein 0.0024 0.0075 0.0119
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.025 0.1074
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0102 0.0812 0.0811
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Echinococcus granulosus g-protein coupled receptor 0.0037 0.0192 0.0191
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0159 0.0217
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0192 0.0263
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0159 0.0217
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0192 0.0263
Onchocerca volvulus 0.0024 0.0075 0.0026
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0135 0.0215
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0283 0.0283
Echinococcus granulosus sodium leak channel non selective protein 0.0033 0.0159 0.0158
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Schistosoma mansoni ran 0.0021 0.0042 0.0056
Plasmodium vivax hypothetical protein, conserved 0.0043 0.025 0.3652
Brugia malayi Cell death protein 3 precursor 0.0083 0.0628 0.1001
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0135 0.0215
Schistosoma mansoni nuclear hormone receptor 0.0118 0.0961 0.132
Toxoplasma gondii ion channel protein 0.0024 0.0075 0.0294
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0024 0.0075 0.0119
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0192 0.0191
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.025 0.1074
Echinococcus multilocularis caspase 3 0.007 0.0511 0.0511
Onchocerca volvulus 0.0035 0.0179 0.0234
Brugia malayi hypothetical protein 0.0115 0.0936 0.1492
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0033 0.0159 0.0158
Onchocerca volvulus 0.0096 0.0752 0.138
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0417 0.5497
Echinococcus granulosus short transient receptor potential channel 6 0.0033 0.016 0.0159
Echinococcus multilocularis transient receptor potential gamma protein 0.0033 0.0159 0.0158
Entamoeba histolytica hypothetical protein 0.0041 0.0232 0.0379
Brugia malayi cation channel family protein 0.0033 0.0159 0.0252
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0062 0.0122
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0897 0.3478
Echinococcus granulosus short transient receptor potential channel 6 0.0033 0.0159 0.0158
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0348 0.5131
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0024 0.0075 0.0119
Schistosoma mansoni amine GPCR 0.0037 0.0192 0.0263
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.0232 0.0231
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0172 0.0638
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0249 0.221 0.3039
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0159 0.0158
Loa Loa (eye worm) melatonin receptor type 1A 0.0037 0.0192 0.0306
Echinococcus granulosus ryanodine receptor 44f 0.0033 0.0159 0.0158
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0284 0.0283
Echinococcus multilocularis cpg binding protein 0.0034 0.0172 0.0171
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0925 0.4377
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0504 0.5572
Brugia malayi follicle stimulating hormone receptor 0.052 0.4777 0.7615
Echinococcus granulosus g protein coupled receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0118 0.0961 0.096
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0033 0.0159 0.0252
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0118 0.0961 0.096
Schistosoma mansoni lozenge 0.0054 0.0356 0.0488
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus granulosus neuropeptide receptor 0.0037 0.0192 0.0191
Brugia malayi GnHR receptor homolog 0.0037 0.0192 0.0306
Echinococcus multilocularis calcium activated potassium channel 0.0033 0.0159 0.0158
Schistosoma mansoni 60S ribosomal protein L21 0.0037 0.0195 0.0267
Loa Loa (eye worm) hypothetical protein 0.0132 0.1094 0.1745
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0498 0.0498
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0033 0.0159 0.0158
Schistosoma mansoni zinc finger protein 0.0118 0.0961 0.132
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.025 0.0494
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus granulosus glycogen phosphorylase 0.055 0.5065 0.5065
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0125 0.1758
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.0247 0.0246
Echinococcus granulosus potassium channel subfamily K 8 0.0024 0.0075 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0192 0.0263
Onchocerca volvulus 0.0024 0.0075 0.0026
Onchocerca volvulus 0.0037 0.0192 0.0261
Loa Loa (eye worm) serotonin transporter b 0.0096 0.0752 0.1199
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0067 0.0482 0.0951
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0787 0.1081
Entamoeba histolytica hypothetical protein 0.0041 0.0232 0.0379
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Loa Loa (eye worm) hypothetical protein 0.0033 0.016 0.0255
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0065 0.0466 0.0465
Plasmodium falciparum metacaspase 1 0.0043 0.025 0.3652
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0096 0.0752 0.1033
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Schistosoma mansoni hypothetical protein 0.0711 0.6587 0.9058
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0179 0.0664
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0192 0.0191
Schistosoma mansoni adenoreceptor 0.0037 0.0192 0.0263
Loa Loa (eye worm) hypothetical protein 0.0042 0.0247 0.0393
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0005 0.001
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0024 0.0075 0.0259
Loa Loa (eye worm) hypothetical protein 0.0677 0.6272 1
Schistosoma mansoni hypothetical protein 0.011 0.0886 0.1217
Mycobacterium ulcerans hypothetical protein 0.0035 0.0179 0.0811
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0129 0.1071 0.1071
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0037 0.0192 0.0263
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0602 0.0827
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0307 0.0306
Loa Loa (eye worm) hypothetical protein 0.0083 0.0628 0.1001
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0042 0.0041
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0249 0.221 0.221
Schistosoma mansoni calcium-activated potassium channel 0.0033 0.0159 0.0217
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0283 0.0389
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0087 0.067 0.3158
Plasmodium vivax metacaspase 1, putative 0.0043 0.025 0.3652
Echinococcus multilocularis snurportin 1 0.0301 0.2699 0.2698
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Leishmania major metacaspase, putative 0.0043 0.025 0.2717
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Echinococcus multilocularis inositol monophosphatase 1 0.0111 0.0897 0.0896
Brugia malayi N-terminal motif family protein 0.0181 0.1558 0.2484
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Echinococcus multilocularis short transient receptor potential channel 6 0.0033 0.016 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1404 0.2772
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0318 0.0317
Echinococcus granulosus g protein coupled receptor 0.0037 0.0192 0.0191
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0115 0.1423
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0417 0.0808
Trichomonas vaginalis inositol monophosphatase, putative 0.0111 0.0897 0.1771
Schistosoma mansoni biogenic amine receptor 0.0037 0.0192 0.0263
Onchocerca volvulus Huntingtin homolog 0.0119 0.0976 0.1827
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0172 0.0274
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Brugia malayi G protein-coupled receptor F59B2.13 0.0037 0.0192 0.0306
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0043 0.025 0.0399
Brugia malayi AKH receptor 0.0037 0.0192 0.0306
Echinococcus granulosus voltage dependent calcium channel 0.0677 0.6272 0.6272
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0159 0.0158
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0062 0.0122
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0037 0.0192 0.0306
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0179 0.0353
Schistosoma mansoni sodium/chloride dependent transporter 0.0096 0.0752 0.1033
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0348 0.1328
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0033 0.0159 0.0158
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0284 0.0283
Brugia malayi hypothetical protein 0.0118 0.0961 0.1531
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0066 0.0473 0.0934
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi hypothetical protein 0.0024 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0181 0.1558 0.2484
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Toxoplasma gondii hypothetical protein 0.0033 0.0159 0.0666
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0925 0.4377
Echinococcus multilocularis neuropeptide s receptor 0.107 1 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0327 0.052
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0159 0.0158
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0096 0.0752 0.1199
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0038 0.0074
Brugia malayi hypothetical protein 0.0053 0.0348 0.0554
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Echinococcus multilocularis FTZ F1 alpha 0.0249 0.221 0.221
Echinococcus multilocularis orexin receptor type 2 0.0037 0.0192 0.0191
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0033 0.0159 0.0158
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.1045 0.4953
Brugia malayi sulfakinin receptor protein 0.0037 0.0192 0.0306
Echinococcus granulosus small conductance calcium activated potassium 0.0024 0.0075 0.0074
Trypanosoma cruzi metacaspase, putative 0.0043 0.025 0.0945
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0024 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0009 0.0018
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0036 0.019 0.0189
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0071 0.007
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0033 0.0159 0.0158
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Leishmania major hypothetical protein, conserved 0.0035 0.0179 0.1911
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0327 0.0326
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0159 0.0158
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0421 0.067
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0628 0.2754
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0159 0.0158
Echinococcus multilocularis JmjC domain containing protein 4 0.0034 0.0172 0.0171
Brugia malayi hypothetical protein 0.0033 0.0159 0.0252
Brugia malayi neuropeptide F receptor 0.0037 0.0192 0.0306
Schistosoma mansoni phd/f-box containing protein 0.0034 0.0172 0.0235
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0129 0.1071 0.1071
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0283 0.0283
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0024 0.0075 0.0119
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0327 0.052
Schistosoma mansoni ryanodine receptor related 0.0033 0.0159 0.0217
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0368 0.0505
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0249 0.221 0.221
Schistosoma mansoni nuclear hormone receptor 0.0249 0.221 0.3039
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.0247 0.0246
Schistosoma mansoni neuropeptide receptor 0.0037 0.0192 0.0263
Onchocerca volvulus 0.0024 0.0075 0.0026
Loa Loa (eye worm) hypothetical protein 0.0161 0.1368 0.218
Trichomonas vaginalis glycogen phosphorylase, putative 0.055 0.5065 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus granulosus Nuclear hormone receptor HR96 0.0118 0.0961 0.096
Brugia malayi nuclear hormone receptor 0.0118 0.0961 0.1531
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0628 0.9367
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0033 0.0159 0.0252
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.0247 0.0246
Echinococcus multilocularis jumonji domain containing 1A 0.0034 0.0172 0.0171
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Schistosoma mansoni nuclear receptor nhr-48 0.0118 0.0961 0.132
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0037 0.0192 0.0263
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0522 0.0717
Onchocerca volvulus 0.0499 0.4582 0.9034
Schistosoma mansoni ap endonuclease 0.006 0.0417 0.0573
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0628 0.1224
Schistosoma mansoni opsin-like receptor 0.0037 0.0192 0.0263
Mycobacterium tuberculosis Conserved protein 0.0035 0.0179 0.0811
Echinococcus multilocularis g-protein coupled receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0028 0.0112 0.0178
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0249 0.221 0.221
Toxoplasma gondii melibiase subfamily protein 0.0099 0.0787 0.3463
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.0247 0.0246
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0232 0.0231
Brugia malayi latrophilin 2 splice variant baaae 0.011 0.0886 0.1412
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0602 0.1115
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0856 0.7965 0.7965
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0232 0.1067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0249 0.221 0.221
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0925 0.8775
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0042 0.0247 0.0246
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0075 0.0259
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0115 0.0537
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0628 0.2958
Schistosoma mansoni hypothetical protein 0.0301 0.2699 0.371
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0249 0.221 0.221
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0249 0.221 0.3524
Brugia malayi nuclear receptor NHR-88 0.0118 0.0961 0.1531
Schistosoma mansoni microtubule-associated protein tau 0.0783 0.7272 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0307 0.0306
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.025 0.0494
Mycobacterium tuberculosis Conserved protein 0.0035 0.0179 0.0811
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0037 0.0192 0.0263
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0787 0.1081
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0897 1
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0125 0.023
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0179 0.0664
Schistosoma mansoni importin beta-1 0.0028 0.0112 0.0153
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0042 0.0247 0.0246
Brugia malayi hypothetical protein 0.0185 0.1601 0.2553
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0161 0.1368 0.218
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0787 0.1081
Schistosoma mansoni neuropeptide receptor 0.0037 0.0192 0.0263
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1404 0.2772
Schistosoma mansoni alpha-1 adrenergic receptor 0.0037 0.0192 0.0263
Brugia malayi Melatonin receptor type 1A 0.0037 0.0192 0.0306
Echinococcus granulosus nuclear receptor nhr 48 0.0118 0.0961 0.096
Echinococcus multilocularis lamin dm0 0.0031 0.0135 0.0134
Echinococcus multilocularis flap endonuclease 1 0.003 0.0125 0.0124
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0344 0.0472
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0118 0.0961 0.1531
Echinococcus granulosus voltage gated potassium channel 0.0033 0.0159 0.0158
Trypanosoma brucei metacaspase 5, putative 0.0043 0.025 0.0945
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0284
Loa Loa (eye worm) hypothetical protein 0.0096 0.0752 0.1199
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0192 0.0191
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0159 0.0217
Echinococcus granulosus potassium large conductance calcium activated 0.0033 0.0159 0.0158
Brugia malayi hypoxia-induced factor 1 0.0171 0.1465 0.2336
Brugia malayi Flap endonuclease-1 0.003 0.0125 0.0199
Echinococcus granulosus peptide allatostatin:somatostatin 0.0037 0.0192 0.0191
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Brugia malayi M-phase phosphoprotein, mpp8 0.0115 0.0935 0.149
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0179 0.1188
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0677 0.6272 0.6272
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0249 0.221 0.3039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0284
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Echinococcus multilocularis serotonin receptor 0.0037 0.0192 0.0191
Schistosoma mansoni phosphatidylserine receptor 0.0034 0.0172 0.0235
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0118 0.0961 0.096
Schistosoma mansoni thyroid hormone receptor 0.0249 0.221 0.3039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0448 0.0614
Echinococcus granulosus lysine specific demethylase 5A 0.0131 0.1089 0.1088
Echinococcus multilocularis conserved hypothetical protein 0.0033 0.0159 0.0158
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0024 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus multilocularis twik family of potassium channels 0.0024 0.0075 0.0074
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0417 0.0748
Loa Loa (eye worm) MBCTL1 0.0053 0.0344 0.0549
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0118 0.0961 0.096
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0448 0.0447
Echinococcus granulosus alpha 1A adrenergic receptor 0.0037 0.0192 0.0191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0307 0.042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0037 0.0192 0.0306
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0238 0.2102 1
Schistosoma mansoni single-minded 0.0055 0.0368 0.0505
Entamoeba histolytica glycogen phosphorylase, putative 0.055 0.5065 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0284 0.0283
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0038 0.0074
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Schistosoma mansoni voltage-gated cation channel 0.0677 0.6272 0.8625
Echinococcus granulosus hypothetical protein 0.0037 0.0192 0.0191
Schistosoma mansoni jumonji domain containing protein 0.0129 0.1071 0.1472
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0249 0.221 0.221
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0179 0.0811
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0417 0.1599
Echinococcus multilocularis voltage dependent calcium channel 0.0677 0.6272 0.6272
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Echinococcus granulosus thyroid hormone receptor alpha 0.0118 0.0961 0.096
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0024 0.0075 0.0119
Brugia malayi CXXC zinc finger family protein 0.0033 0.0154 0.0245
Echinococcus multilocularis allatostatin A receptor 0.0037 0.0192 0.0191
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0111 0.0897 0.1771
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0009 0.0018
Echinococcus multilocularis voltage gated potassium channel 0.0033 0.0159 0.0158
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0111 0.0897 0.1771
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0033 0.0159 0.0158
Schistosoma mansoni opsin-like receptor 0.0037 0.0192 0.0263
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0247 0.0338
Echinococcus granulosus dnaJ subfamily B 0.0464 0.4247 0.4247
Schistosoma mansoni hypothetical protein 0.0041 0.0232 0.0318
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0118 0.0961 0.132
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0284
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0135 0.0215
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0417 0.0417
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0247 0.0488
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0358 0.1669
Onchocerca volvulus 0.0024 0.0075 0.0026
Brugia malayi nuclear receptor NHR-88 0.0249 0.221 0.3524
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0159 0.0158
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0009 0.0014
Schistosoma mansoni opsin-like receptor 0.0037 0.0192 0.0263
Toxoplasma gondii transporter, cation channel family protein 0.0254 0.2256 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Schistosoma mansoni glycogen phosphorylase 0.055 0.5065 0.6965
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Trypanosoma cruzi ion transport protein, putative 0.0024 0.0075 0.0259
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0062 0.0206
Brugia malayi bHLH-PAS transcription factor 0.0041 0.0232 0.037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0504 0.0803
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0417 0.6181
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0408 0.065
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0033 0.0159 0.0252
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0677 0.6272 0.6272
Schistosoma mansoni hypothetical protein 0.0037 0.0192 0.0263
Onchocerca volvulus Neuropeptide F receptor homolog 0.0037 0.0192 0.0261
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0118 0.0961 0.1531
Loa Loa (eye worm) TWK-28 protein 0.0024 0.0075 0.0119
Brugia malayi olfactory channel protein osm-9 0.0033 0.016 0.0255
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0498 0.2178
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0037 0.0192 0.0191
Brugia malayi intermediate filament protein 0.0031 0.0135 0.0215
Echinococcus granulosus jumonji domain containing 1A 0.0034 0.0172 0.0171
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0179 0.0353
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0024 0.0075 0.0119
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0238 0.2102 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0249 0.221 0.3039
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0628 0.2958
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0132 0.1094 0.1504
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0504 0.0503
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0498 0.2338
Echinococcus granulosus voltage dependent calcium channel 0.0254 0.2256 0.2256
Echinococcus multilocularis glycogen phosphorylase 0.055 0.5065 0.5065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0249 0.221 0.3524
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0102 0.0812 0.1116
Brugia malayi Nuclear hormone receptor-like 1 0.0132 0.1094 0.1745
Brugia malayi hypothetical protein 0.0132 0.1094 0.1745
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0033 0.0159 0.0217
Loa Loa (eye worm) glutathione reductase 0.005 0.0318 0.0507
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0042 0.0128
Trichomonas vaginalis esterase, putative 0.0035 0.0179 0.0353
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0024 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0327 0.052
Brugia malayi Transient-receptor-potential like protein 0.0033 0.0159 0.0252
Toxoplasma gondii thioredoxin reductase 0.005 0.0318 0.1377
Echinococcus granulosus Nuclear hormone receptor HR96 0.0118 0.0961 0.096
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0034 0.0172 0.0725
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0099 0.0787 0.0786
Onchocerca volvulus 0.0035 0.0179 0.0234
Brugia malayi glutathione reductase 0.005 0.0318 0.0507
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0504 0.2365
Brugia malayi Steroid receptor seven-up type 2 0.0249 0.221 0.3524
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0037 0.0192 0.0263
Schistosoma mansoni caspase-7 (C14 family) 0.0083 0.0628 0.0862
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0498 0.551
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0113 0.0917 0.0916
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0076 0.0565 0.0565
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0498 0.2338
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0037 0.0192 0.0191
Echinococcus granulosus sodium channel protein 0.0033 0.0159 0.0158
Brugia malayi Dopamine receptor 0.0037 0.0192 0.0306
Leishmania major GTP-binding protein, putative 0.0021 0.0042 0.0368
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0179 0.2568
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0024 0.0075 0.0119
Loa Loa (eye worm) voltage-gated potassium channel 0.0033 0.0159 0.0252
Loa Loa (eye worm) hypothetical protein 0.0031 0.0135 0.0215
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0192 0.0263
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0037 0.0192 0.0306
Echinococcus multilocularis caspase 2 0.0083 0.0628 0.0627
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Echinococcus multilocularis potassium channel subfamily K 8 0.0024 0.0075 0.0074
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0192 0.0191
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0249 0.221 0.3524
Loa Loa (eye worm) hypothetical protein 0.0132 0.1094 0.1745
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0179 0.0664
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0504 0.0503
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0284 0.0283
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0192 0.0263
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Brugia malayi Cytochrome P450 family protein 0.0026 0.0091 0.0145
Schistosoma mansoni hypothetical protein 0.0024 0.0075 0.0102
Toxoplasma gondii hypothetical protein 0.0033 0.0159 0.0666
Echinococcus granulosus FTZ F1 alpha 0.0249 0.221 0.221
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0037 0.0192 0.0306
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0034 0.0172 0.0725
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0062 0.0122
Brugia malayi jmjC domain containing protein 0.0034 0.0172 0.0274
Brugia malayi RNA, U transporter 1 0.008 0.0605 0.0964
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0159 0.0158
Echinococcus granulosus cpg binding protein 0.0034 0.0172 0.0171
Mycobacterium ulcerans transmembrane cation transporter 0.0024 0.0075 0.0316
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Loa Loa (eye worm) hypoxia-induced factor 1 0.0171 0.1465 0.2336
Echinococcus multilocularis geminin 0.0711 0.6587 0.6587
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.2221 0.4385
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0037 0.0192 0.0191
Onchocerca volvulus 0.0037 0.0192 0.0261
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0498 0.0498
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0024 0.0075 0.0119
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0179 0.0244
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0247 0.0338
Toxoplasma gondii transporter, cation channel family protein 0.0033 0.0159 0.0666
Brugia malayi hypothetical protein 0.043 0.392 0.625
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.025 0.2221 0.3541
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Schistosoma mansoni inositol monophosphatase 0.0111 0.0897 0.1233
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Onchocerca volvulus 0.0033 0.0154 0.0184
Loa Loa (eye worm) hypothetical protein 0.0132 0.1094 0.1745
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0192 0.0191
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1404 0.2772
Schistosoma mansoni cpg binding protein 0.0033 0.0154 0.021
Trichomonas vaginalis ran, putative 0.0021 0.0042 0.0082
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus granulosus caspase 8 0.0043 0.025 0.0249
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.2221 0.4385
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0249 0.221 0.3524
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Schistosoma mansoni intermediate filament proteins 0.0031 0.0135 0.0185
Echinococcus multilocularis sex peptide receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.008 0.0602 0.0959
Mycobacterium ulcerans hypothetical protein 0.0023 0.0062 0.0253
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0037 0.0192 0.0191
Schistosoma mansoni transient receptor potential channel 4 0.0033 0.0159 0.0217
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Schistosoma mansoni hypothetical protein 0.0051 0.0327 0.0448
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0498 0.2338
Onchocerca volvulus 0.0024 0.0075 0.0026
Echinococcus multilocularis thyroid hormone receptor alpha 0.0249 0.221 0.221
Leishmania major importin beta-1 subunit, putative 0.0023 0.0062 0.0593
Onchocerca volvulus Cell death protein 3 homolog 0.0083 0.0628 0.1131
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0348 0.1328
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0033 0.0159 0.0158
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus granulosus lamin dm0 0.0031 0.0135 0.0134
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0034 0.0172 0.0638
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0033 0.0159 0.0158
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0348 0.1509
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0099 0.0787 0.7371
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0033 0.0159 0.0586
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0033 0.0159 0.0217
Onchocerca volvulus 0.0035 0.0179 0.0234
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0159 0.0666
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0036 0.019 0.0189
Echinococcus multilocularis musashi 0.0031 0.0135 0.0134
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.016 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Onchocerca volvulus 0.0031 0.0135 0.0147
Onchocerca volvulus 0.0076 0.057 0.1016
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0132 0.1094 0.1504
Loa Loa (eye worm) hypothetical protein 0.0115 0.0936 0.1492
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1404 0.2772
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0897 0.3478
Echinococcus multilocularis G protein coupled receptor 139 0.0037 0.0192 0.0191
Brugia malayi jmjC domain containing protein 0.0034 0.0172 0.0274
Brugia malayi carbohydrate phosphorylase 0.055 0.5065 0.8076
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1404 0.2772
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0033 0.0159 0.0217
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0033 0.0159 0.0252
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0417 0.0665
Schistosoma mansoni nuclear hormone receptor 0.0118 0.0961 0.132
Leishmania major potassium channel subunit-like protein 0.0024 0.0075 0.0744
Brugia malayi RE15519p 0.0037 0.0192 0.0306
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0038 0.0074
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0159 0.0217
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0033 0.0159 0.0586
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0318 0.0507
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0179 0.0811
Brugia malayi conserved hypotetical protein 0.0118 0.0961 0.1531
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0249 0.221 0.3524
Loa Loa (eye worm) ion channel NompC 0.0033 0.0159 0.0252
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0084 0.0637 0.0637
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0192 0.0191
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.1045 0.4953
Schistosoma mansoni protein phosphatase 2C 0.0034 0.0172 0.0235
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Echinococcus multilocularis nuclear receptor nhr 48 0.0118 0.0961 0.096
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.1089 0.1497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Plasmodium falciparum JmjC domain-containing protein, putative 0.0034 0.0172 0.2467
Schistosoma mansoni voltage-gated ion channel 0.0033 0.0159 0.0217
Leishmania major hypothetical protein, conserved 0.0033 0.0159 0.1686
Echinococcus multilocularis dnaJ subfamily B 0.0464 0.4247 0.4247
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0249 0.221 0.3524
Schistosoma mansoni transient receptor potential channel 0.0033 0.016 0.0219
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0132 0.1094 0.1094
Schistosoma mansoni jumonji domain containing protein 0.0034 0.0172 0.0235
Entamoeba histolytica hypothetical protein 0.0023 0.0062 0.004
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0112 0.0404
Brugia malayi ORL1-like opioid receptor 0.0037 0.0192 0.0306
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0897 0.3478
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0473 0.065
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0161 0.1368 0.218
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0132 0.1094 0.1094
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0179 0.0284
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Leishmania major ion transport protein-like protein 0.0024 0.0075 0.0744
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.2221 0.4385
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0283 0.0283
Onchocerca volvulus 0.0041 0.0232 0.0341
Loa Loa (eye worm) hypothetical protein 0.0221 0.1943 0.3097
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0023 0.0062 0.0098
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0033 0.0159 0.1686
Treponema pallidum sodium- and chloride- dependent transporter 0.0096 0.0752 1
Onchocerca volvulus 0.0046 0.0284 0.0444
Trypanosoma brucei metacaspase 0.0043 0.025 0.0945
Echinococcus multilocularis phd:f box containing protein 0.0034 0.0172 0.0171
Toxoplasma gondii transporter, cation channel family protein 0.0033 0.0159 0.0666
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0417 0.4599
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0417 0.1599
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0033 0.0159 0.0252
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0249 0.221 0.3039
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0179 0.0178
Brugia malayi nuclear receptor NHR-67 0.0118 0.0961 0.1531
Loa Loa (eye worm) calcium channel 0.0677 0.6272 1
Leishmania major trypanothione reductase 0.005 0.0318 0.3484
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0118 0.0961 0.132
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0179 0.0811
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.016 0.0159
Plasmodium vivax JmjC domain containing protein 0.0034 0.0172 0.2467
Loa Loa (eye worm) hypothetical protein 0.0043 0.025 0.0399
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.1488 0.2937
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0042 0.0247 0.0246
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Echinococcus granulosus shaker cognate 0.0033 0.0159 0.0158
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0033 0.0159 0.0252
Leishmania major protein kinase, putative 0.0024 0.0069 0.0679
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0118 0.0961 0.1797
Loa Loa (eye worm) hypothetical protein 0.043 0.392 0.625
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0283 0.0283
Mycobacterium ulcerans epimerase 0.0023 0.0062 0.0253
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0289 0.046
Echinococcus granulosus importin subunit beta 1 0.0028 0.0112 0.0111
Echinococcus multilocularis serotonin receptor 0.0037 0.0192 0.0191
Brugia malayi beta-lactamase 0.0035 0.0179 0.0284
Entamoeba histolytica glycogenphosphorylase, putative 0.0238 0.2102 0.4101
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0024 0.0075 0.0119
Echinococcus multilocularis tumor protein p63 0.0383 0.3482 0.3481
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0327 0.0326
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.1089 0.1497
Giardia lamblia Hypothetical protein 0.0024 0.0075 0.0131
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Onchocerca volvulus 0.0037 0.0192 0.0261
Echinococcus multilocularis small conductance calcium activated potassium 0.0024 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0115 0.0935 0.149
Echinococcus granulosus phd:f box containing protein 0.0034 0.0172 0.0171
Echinococcus granulosus Glycosyl transferase family 35 0.055 0.5065 0.5065
Echinococcus multilocularis twik family of potassium channels 0.0024 0.0075 0.0074
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0008
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0504 0.0692
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0318 0.1478
Echinococcus multilocularis microtubule associated protein 2 0.0783 0.7272 0.7272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0448 0.0614
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0091 0.0395
Loa Loa (eye worm) follicle stimulating hormone receptor 0.052 0.4777 0.7615
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0112 0.0459
Loa Loa (eye worm) hypothetical protein 0.0185 0.1601 0.2553
Schistosoma mansoni amine GPCR 0.0386 0.3506 0.4821
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0249 0.221 0.3524
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0249 0.221 0.3524
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0033 0.0159 0.0158
Brugia malayi jmjC domain containing protein 0.0131 0.1089 0.1736
Echinococcus granulosus fmrfamide receptor 0.0037 0.0192 0.0191
Brugia malayi Thioredoxin reductase 0.005 0.0318 0.0507
Loa Loa (eye worm) hypothetical protein 0.0033 0.0159 0.0252
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0024 0.0075 0.0119
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0033 0.0159 0.0217
Brugia malayi hypothetical protein 0.004 0.0222 0.0354
Brugia malayi ecdysteroid receptor 0.0249 0.221 0.3524
Loa Loa (eye worm) hypothetical protein 0.011 0.0886 0.1412
Entamoeba histolytica hypothetical protein 0.0041 0.0232 0.0379
Echinococcus multilocularis potassium large conductance calcium activated 0.0033 0.0159 0.0158
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0287 0.2563 1
Brugia malayi orphan nuclear receptor NR2E1 0.0118 0.0961 0.1531
Schistosoma mansoni caspase-3 (C14 family) 0.0113 0.0917 0.126
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0024 0.0075 0.0119
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0023 0.0062 0.0253
Echinococcus granulosus GPCR family 2 0.0051 0.0327 0.0326
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0249 0.221 0.3524
Brugia malayi putative neuropeptide receptor NPR1 0.0037 0.0192 0.0306
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0125 0.1308
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0042 0.0128
Echinococcus granulosus tachykinin peptides receptor 99D 0.0037 0.0192 0.0191
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.0247 0.0338
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0112 0.0404
Onchocerca volvulus Glycogen phosphorylase homolog 0.055 0.5065 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0307 0.0306
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0344 0.0344
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0102 0.0812 0.0811
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0249 0.221 0.3524
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0038 0.0074
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0037 0.0192 0.0191
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0358 0.1669
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.1404 0.2682
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0192 0.0191
Entamoeba histolytica glycogen phosphorylase, putative 0.0238 0.2102 0.4101
Brugia malayi putative neuropeptide receptor 0.0037 0.0192 0.0306
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0249 0.221 0.221
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0348 0.1328
Loa Loa (eye worm) hypothetical protein 0.0053 0.0348 0.0554
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0024 0.0075 0.0119
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.025 0.0494
Schistosoma mansoni amine GPCR 0.0037 0.0192 0.0263
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.1977 0.9405
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0163 0.0322
Onchocerca volvulus 0.0037 0.0192 0.0261
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0037 0.0192 0.0306
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi hypothetical protein 0.0041 0.0232 0.0369
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0417 0.1599
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0033 0.0159 0.0252
Schistosoma mansoni two-pore calcium channel 0.0033 0.0159 0.0217
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0249 0.221 0.221
Loa Loa (eye worm) MH2 domain-containing protein 0.0133 0.1105 0.1761
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0247 0.0488
Brugia malayi Nuclear hormone receptor E75 0.0118 0.0961 0.1531
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0159 0.0158
Echinococcus multilocularis neuropeptide receptor A26 0.107 1 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) TYRA-2 protein 0.0037 0.0192 0.0306
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi Melibiase family protein 0.0066 0.0473 0.0754
Schistosoma mansoni amine GPCR 0.0037 0.0192 0.0263
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0125 0.0517
Echinococcus granulosus caspase 0.0113 0.0917 0.0916
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0042 0.0041
Brugia malayi cation channel family protein 0.0033 0.0159 0.0252
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0091 0.0145
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0115 0.16
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0033 0.0159 0.0252
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0192 0.0306
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0249 0.221 0.3039
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0076 0.0565 0.0901
Echinococcus granulosus twik family of potassium channels 0.0024 0.0075 0.0074
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0284 0.0389
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0677 0.6272 0.6272
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0284 0.0452
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0038 0.0074
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Brugia malayi Nuclear hormone receptor-like 1 0.0132 0.1094 0.1745
Entamoeba histolytica hypothetical protein 0.0041 0.0232 0.0379
Echinococcus multilocularis potassium channel subfamily K 0.0024 0.0075 0.0074
Leishmania major hypothetical protein, unknown function 0.0033 0.0159 0.1686
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0179 0.0353
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0024 0.0075 0.0316
Echinococcus granulosus somatostatin receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0307 0.0488
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0358 0.0357
Brugia malayi ecdysone receptor 0.0118 0.0961 0.1531
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.1558 0.2991
Brugia malayi G protein-coupled receptor 0.0037 0.0192 0.0306
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0087 0.067 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0192 0.0191
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0192 0.0191
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0111 0.0897 0.3952
Brugia malayi Serotonin receptor 0.0037 0.0192 0.0306
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0192 0.0191
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0358 0.3013
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0344 0.0344
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0043 0.025 0.0343
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0099 0.0787 0.0786
Trypanosoma cruzi metacaspase, putative 0.0043 0.025 0.0945
Echinococcus multilocularis ryanodine receptor 44f 0.0033 0.0159 0.0158
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0192 0.0191
Brugia malayi Probable ClpP-like protease 0.0083 0.0628 0.1001
Brugia malayi Nuclear hormone receptor-like 1 0.0249 0.221 0.3524
Echinococcus granulosus single minded 2 0.0045 0.0269 0.0268
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0417 0.1952
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Loa Loa (eye worm) runx1 0.0054 0.0356 0.0567
Loa Loa (eye worm) hypothetical protein 0.0066 0.0473 0.0754
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0011
Echinococcus granulosus neuropeptide FF receptor 2 0.0037 0.0192 0.0191
Loa Loa (eye worm) norepinephrine transporter 0.0096 0.0752 0.1199
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0034 0.0172 0.0235
Echinococcus multilocularis neuropeptide FF receptor 2 0.0037 0.0192 0.0191
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Echinococcus multilocularis calcium activated potassium channel variant 0.0024 0.0075 0.0074
Schistosoma mansoni biogenic amine receptor 0.0037 0.0192 0.0263
Brugia malayi Cytochrome P450 family protein 0.0026 0.0091 0.0145
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi G-protein coupled receptor 0.0037 0.0192 0.0306
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0179 0.0353
Loa Loa (eye worm) nuclear receptor NHR-67 0.0118 0.0961 0.1531
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Brugia malayi Inositol-1 0.0111 0.0897 0.143
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0037 0.0192 0.0306
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Schistosoma mansoni cpg binding protein 0.0034 0.0172 0.0235
Loa Loa (eye worm) voltage-gated calcium channel 0.0033 0.0159 0.0252
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0417 0.0417
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0628 0.2754
Echinococcus multilocularis GPCR, family 2 0.0051 0.0327 0.0326
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0327 0.0326
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0419 0.0418
Brugia malayi beta-lactamase family protein 0.0035 0.0179 0.0284
Schistosoma mansoni biogenic amine receptor 0.0037 0.0192 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0307 0.042
Leishmania major hypothetical protein, conserved 0.0024 0.0075 0.0744
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.0247 0.0338
Onchocerca volvulus 0.0033 0.0159 0.0194
Entamoeba histolytica glycogen phosphorylase, putative 0.0238 0.2102 0.4101
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Onchocerca volvulus 0.0037 0.0192 0.0261
Echinococcus granulosus twik family of potassium channels 0.0024 0.0075 0.0074
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0037 0.0192 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0249 0.221 0.3524
Schistosoma mansoni nuclear receptor 0.0118 0.0961 0.132
Brugia malayi nuclear hormone receptor 0.0249 0.221 0.3524
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0417 0.6181
Schistosoma mansoni thyroid hormone receptor 0.0249 0.221 0.3039
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.025 0.0945
Loa Loa (eye worm) glycogen phosphorylase 0.055 0.5065 0.8076
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0096 0.0752 0.1199
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0033 0.0159 0.0158
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0115 0.16
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0099 0.0787 0.3717
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0628 0.9367
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0504 0.2365
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0179 0.0811
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0192 0.0306
Echinococcus granulosus potassium channel subfamily K 8 0.0024 0.0075 0.0074
Onchocerca volvulus Bile acid receptor homolog 0.0249 0.221 0.4294
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0163 0.0322
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0307 0.0306
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.2021 0.202
Echinococcus granulosus caspase 2 0.0083 0.0628 0.0627
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0498 0.0684
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0344 0.0549
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Brugia malayi nuclear receptor RXR 0.0132 0.1094 0.1745
Brugia malayi Pre-SET motif family protein 0.0064 0.0448 0.0713
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0172 0.0638
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0112 0.0111
Echinococcus granulosus calcium activated potassium channel variant 0.0024 0.0075 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0195 0.0267
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0377 0.0517
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0024 0.0075 0.0259
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0071 0.007
Schistosoma mansoni histamine h1 receptor 0.0037 0.0192 0.0263
Echinococcus granulosus two pore calcium channel protein 1 0.0033 0.0159 0.0158
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0417 0.0824
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0249 0.221 0.3524
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0192 0.0263
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.025 0.0494
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0327 0.0326
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0033 0.0159 0.0158
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0249 0.221 0.221
Onchocerca volvulus 0.004 0.0222 0.0321
Echinococcus granulosus intermediate filament protein 0.0031 0.0135 0.0134
Loa Loa (eye worm) hypothetical protein 0.0035 0.0179 0.0284
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi hypothetical protein 0.0119 0.0976 0.1555
Loa Loa (eye worm) beta-lactamase 0.0035 0.0179 0.0284
Loa Loa (eye worm) ryanodine receptor 0.0033 0.0159 0.0252
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0075 0.0259
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0677 0.6272 0.6272
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0024 0.0075 0.0067
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0222 0.0222
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0192 0.0191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Onchocerca volvulus 0.0037 0.0192 0.0261
Echinococcus granulosus neuropeptide receptor A26 0.107 1 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.1045 0.4953
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0159 0.0158
Onchocerca volvulus 0.0037 0.0192 0.0261
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0179 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.025 0.0494
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0099 0.0787 0.0786
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Schistosoma mansoni hypothetical protein 0.0037 0.0192 0.0263
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Echinococcus granulosus caspase 3 0.007 0.0511 0.0511
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Schistosoma mansoni nuclear receptor 0.0118 0.0961 0.132
Loa Loa (eye worm) hypothetical protein 0.0119 0.0976 0.1555
Brugia malayi jmjC domain containing protein 0.0034 0.0172 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0229 0.2021 0.3221
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0249 0.221 0.3524
Echinococcus granulosus glycogen phosphorylase 0.055 0.5065 0.5065
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0677 0.6272 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0358 0.0357
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0172 0.0274
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0192 0.0306
Schistosoma mansoni RAR-like nuclear receptor 0.0249 0.221 0.3039
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0037 0.0192 0.0263
Loa Loa (eye worm) nuclear hormone receptor 0.0118 0.0961 0.1531
Echinococcus granulosus JmjC domain containing protein 4 0.0034 0.0172 0.0171
Schistosoma mansoni neuropeptide receptor 0.0037 0.0192 0.0263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0249 0.221 0.3524
Loa Loa (eye worm) hypothetical protein 0.0249 0.221 0.3524
Echinococcus multilocularis lysine specific demethylase 5A 0.0129 0.1071 0.1071
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0498 0.2338
Brugia malayi hypothetical protein 0.0034 0.017 0.027
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0118 0.0961 0.096
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0283 0.0389
Toxoplasma gondii endonuclease IV APN 0.0087 0.067 0.2941
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Echinococcus granulosus dro:myosuppressin receptor 0.0037 0.0192 0.0191
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0287 0.2563 1
Schistosoma mansoni caspase-7 (C14 family) 0.0113 0.0917 0.126
Echinococcus multilocularis serotonin transporter 0.0096 0.0752 0.0751
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0179 0.0811
Plasmodium falciparum metacaspase-like protein 0.0043 0.025 0.3652
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0091 0.0323
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0076 0.0565 0.0565
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0033 0.0159 0.0158
Echinococcus granulosus snurportin 1 0.0301 0.2699 0.2698
Loa Loa (eye worm) hypothetical protein 0.0254 0.2256 0.3597
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0249 0.221 0.3524
Echinococcus multilocularis Glycosyl transferase, family 35 0.055 0.5065 0.5065
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0192 0.0191
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0024 0.0075 0.0119
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0192 0.0263
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0033 0.0159 0.0194
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0301 0.2699 0.4302
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0344 0.0344
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0159 0.0158
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0159 0.0158
Schistosoma mansoni neuropeptide receptor 0.0037 0.0192 0.0263
Loa Loa (eye worm) hypothetical protein 0.0046 0.0284 0.0452
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0069 0.0504 0.2365
Echinococcus multilocularis voltage dependent calcium channel 0.0677 0.6272 0.6272
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0232 0.0231
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0448 0.0447
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0284 0.0444
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.0247 0.0393
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0247 0.0338
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.2221 0.4385
Onchocerca volvulus 0.0024 0.0075 0.0026
Onchocerca volvulus 0.0115 0.0935 0.1745
Loa Loa (eye worm) hypothetical protein 0.0087 0.067 0.1067
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0787 0.1081
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.0075 0.0102
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Brugia malayi hypothetical protein 0.0037 0.0192 0.0306
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0498 0.0684
Echinococcus granulosus microtubule associated protein 2 0.0783 0.7272 0.7272
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0222 0.0222
Brugia malayi jmjC domain containing protein 0.0034 0.0172 0.0274
Brugia malayi hypothetical protein 0.0229 0.2021 0.3221
Brugia malayi Cyclic-nucleotide gated cation channel 0.0042 0.0247 0.0393
Brugia malayi Nuclear hormone receptor E75 0.0118 0.0961 0.1531
Echinococcus granulosus serotonin transporter 0.0096 0.0752 0.0751
Plasmodium falciparum flap endonuclease 1 0.003 0.0125 0.1758
Onchocerca volvulus Huntingtin homolog 0.0119 0.0976 0.1827
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0066
Schistosoma mansoni coup transcription factor 0.0249 0.221 0.3039
Leishmania major hypothetical protein, conserved 0.0053 0.0348 0.3818
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0179 0.0178
Echinococcus multilocularis sodium leak channel non selective protein 0.0033 0.0159 0.0158
Schistosoma mansoni twik family of potassium channels-related 0.0024 0.0075 0.0102
Onchocerca volvulus 0.0115 0.0935 0.1745
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0024 0.0075 0.0119
Schistosoma mansoni glycogen phosphorylase 0.0238 0.2102 0.289
Toxoplasma gondii hypothetical protein 0.0028 0.0115 0.047
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0284 0.0389
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Entamoeba histolytica glycogen phosphorylase, putative 0.055 0.5065 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0192 0.0263
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0318 0.1211
Loa Loa (eye worm) hypothetical protein 0.0024 0.0075 0.0119
Brugia malayi nuclear hormone receptor family member nhr-6 0.0118 0.0961 0.1531
Onchocerca volvulus 0.0037 0.0192 0.0261
Echinococcus multilocularis Protein lozenge 0.0054 0.0356 0.0355
Loa Loa (eye worm) hypothetical protein 0.0037 0.0192 0.0306
Trypanosoma cruzi ion transport protein, putative 0.0024 0.0075 0.0259
Loa Loa (eye worm) hypothetical protein 0.0118 0.0961 0.1531
Echinococcus granulosus voltage gated hydrogen channel 1 0.0033 0.0159 0.0158
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0042 0.0065
Mycobacterium leprae Probable lipase LipE 0.0035 0.0179 0.1188
Loa Loa (eye worm) hypothetical protein 0.0221 0.1943 0.3097
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0417 0.0824
Toxoplasma gondii ABC1 family protein 0.0035 0.0179 0.0755
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0283 0.0451
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0628 0.833
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.1488 0.2937
Echinococcus multilocularis somatostatin receptor 0.0037 0.0192 0.0191
Brugia malayi nuclear receptor RXR 0.0118 0.0961 0.1531
Brugia malayi voltage-dependent calcium channel 0.0033 0.0159 0.0252
Onchocerca volvulus 0.0037 0.0192 0.0261
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0925 0.4377
Plasmodium falciparum thioredoxin reductase 0.005 0.0318 0.4682
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0628 0.0862
Schistosoma mansoni hypothetical protein 0.0024 0.0071 0.0096
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0159 0.0217

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 63 uM Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicase ChEMBL. 14695816
IC50 (functional) = 63 uM Ability to inhibit in vitro ATPase activity of human papillomavirus (HPV6) E1 helicase ChEMBL. 14695816

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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