Detailed information for compound 402581

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1347.5 | Formula: C63H82N18O14S
  • H donors: 17 H acceptors: 16 LogP: -2.67 Rotable bonds: 45
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@@H]1C(=O)NCC(=O)N)CCCN=C(N)N)CC(C)C)Cc1nc2c(s1)cccc2)Cc1ccc(cc1)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)N)Cc1c[nH]cn1
  • InChi: 1S/C63H82N18O14S/c1-33(2)23-43(55(88)74-42(12-7-21-69-63(66)67)62(95)81-22-8-13-49(81)61(94)71-30-51(65)84)76-59(92)47(27-52-73-41-11-5-6-14-50(41)96-52)79-56(89)44(24-34-15-17-37(83)18-16-34)77-60(93)48(31-82)80-57(90)45(25-35-28-70-40-10-4-3-9-38(35)40)78-58(91)46(26-36-29-68-32-72-36)75-54(87)39(64)19-20-53(85)86/h3-6,9-11,14-18,28-29,32-33,39,42-49,70,82-83H,7-8,12-13,19-27,30-31,64H2,1-2H3,(H2,65,84)(H,68,72)(H,71,94)(H,74,88)(H,75,87)(H,76,92)(H,77,93)(H,78,91)(H,79,89)(H,80,90)(H,85,86)(H4,66,67,69)/t39-,42-,43-,44-,45-,46-,47-,48-,49+/m0/s1
  • InChiKey: FJOUZHSSMANHHO-VLWUCKPRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.007 0.0259 0.0717
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0103 0.1528
Entamoeba histolytica serine/threonine protein kinase, putative 0.019 0.0815 0.2209
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0791 0.3609 1
Echinococcus granulosus geminin 0.0166 0.0706 0.0706
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0069 0.0503
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0304 0.1347 0.1347
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0024 0.0047
Giardia lamblia Hypothetical protein 0.007 0.0259 0.1
Echinococcus multilocularis serine protein kinase ATM 0.0169 0.0721 0.072
Brugia malayi Death domain containing protein 0.0014 0.0001 0.0002
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0036 0.0103 0.0275
Loa Loa (eye worm) hypothetical protein 0.0069 0.0254 0.0513
Entamoeba histolytica hypothetical protein 0.0652 0.2961 0.8194
Schistosoma mansoni lamin 0.0026 0.0057 0.0102
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0069 0.0503
Brugia malayi Casein kinase II, alpha chain 0.0135 0.0563 0.1561
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.018 0.044
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0023 0.0022
Echinococcus granulosus expressed conserved protein 0.0161 0.0682 0.0682
Schistosoma mansoni neprilysin-2 (M13 family) 0.0047 0.0152 0.0272
Echinococcus multilocularis 0.007 0.0259 0.0259
Toxoplasma gondii peptidase family M13 protein 0.0093 0.0366 0.2673
Echinococcus multilocularis expressed conserved protein 0.0161 0.0682 0.0682
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.102 0.2064
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0259 0.066
Loa Loa (eye worm) phosphatidylinositol 3 0.0228 0.0992 0.2008
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0722 0.195
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0045
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.01 0.0099
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0024 0.0047
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0791 0.3609 1
Schistosoma mansoni hypothetical protein 0.0024 0.0047 0.0084
Loa Loa (eye worm) hypothetical protein 0.007 0.0261 0.0528
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.007 0.007
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0304 0.1347 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.018 0.044
Giardia lamblia Phosphatidylinositol 4-kinase 0.007 0.0259 0.1
Loa Loa (eye worm) RNA binding protein 0.0057 0.0199 0.0403
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0069 0.0131
Brugia malayi SH2 domain containing protein 0.0671 0.305 0.8452
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0563 0.1508
Toxoplasma gondii LsmAD domain-containing protein 0.0022 0.0036 0.0258
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.007 0.0259 0.066
Entamoeba histolytica protein kinase rad3, putative 0.0155 0.0654 0.176
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.007 0.0259 0.066
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0032 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.0026 0.0057 0.0115
Trypanosoma cruzi polo-like protein kinase, putative 0.019 0.0815 0.2256
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0032 0.0031
Schistosoma mansoni hypothetical protein 0.0095 0.0376 0.0671
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0047 0.0154 0.031
Brugia malayi TAR-binding protein 0.0057 0.0199 0.0553
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0023 0.0022
Trypanosoma brucei Casein kinase II 0.0135 0.0563 0.3687
Loa Loa (eye worm) hypothetical protein 0.028 0.1233 0.2496
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0152 0.0272
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0014 0.0001 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0385 0.1011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.1243 0.3402
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0001 0.000006204
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0069 0.1034
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0158 0.0669 0.1354
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0158 0.0669 0.1803
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0011 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.1369 0.3754
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0027 0.0058 0.0058
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0318 0.141 0.1409
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0158 0.0669 1
Echinococcus granulosus glycogen synthase kinase 3 beta 0.005 0.0169 0.0168
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1218 0.5588 0.5588
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0377 0.0987
Onchocerca volvulus 0.0099 0.0396 0.2804
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.004 0.008
Trypanosoma cruzi polo-like protein kinase, putative 0.019 0.0815 0.2256
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0069 0.0131
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0815 0.2209
Brugia malayi Protein kinase domain containing protein 0.0318 0.141 0.3906
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0103 0.0725
Schistosoma mansoni neprilysin 0.0024 0.0047 0.0084
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0165 0.0703 0.1897
Brugia malayi Protein kinase domain containing protein 0.0132 0.0549 0.1521
Schistosoma mansoni tar DNA-binding protein 0.0057 0.0199 0.0356
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.007 0.0259 0.0718
Schistosoma mansoni hypothetical protein 0.0166 0.0706 0.1263
Echinococcus multilocularis high voltage activated calcium channel beta 0.0086 0.0333 0.0332
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0047 0.0152 0.0272
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0344 0.0343
Brugia malayi Peptidase family M13 containing protein 0.0093 0.0366 0.1015
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0434 1
Entamoeba histolytica hypothetical protein 0.007 0.0259 0.066
Toxoplasma gondii hypothetical protein 0.0019 0.0024 0.017
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Loa Loa (eye worm) hypothetical protein 0.0093 0.0366 0.0741
Brugia malayi hypoxia-induced factor 1 0.0149 0.0626 0.1735
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.1275 0.3492
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.004 0.007
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.007 0.0259 0.066
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0032 0.0082 0.0145
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0254 0.0513
Loa Loa (eye worm) hypothetical protein 0.0093 0.0366 0.0741
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.141 0.2522
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.006 0.0215 0.0214
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0039
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0345 0.1536 0.2748
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0069 0.5
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.007 0.0259 0.3873
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0001
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.004 0.007
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0815 0.2209
Echinococcus granulosus tar DNA binding protein 0.0057 0.0199 0.0199
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.005 0.0169 0.0301
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0036 0.0103 0.0669
Schistosoma mansoni tar DNA-binding protein 0.0057 0.0199 0.0356
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0032 0.0088
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.0024 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0057 0.0199 0.0356
Schistosoma mansoni hypothetical protein 0.0031 0.0077 0.0137
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0036 0.0528
Brugia malayi hypothetical protein 0.0022 0.0036 0.01
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0215 0.1403
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0171 0.0728 0.0728
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0000062211
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0158 0.0669 0.1801
Leishmania major hypothetical protein, conserved 0.0814 0.3712 1
Brugia malayi PXA domain containing protein 0.002 0.0029 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0815 0.1457
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0343 0.1527 0.1527
Plasmodium vivax hypothetical protein 0.007 0.0259 0.3873
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0298 0.1317 0.3609
Loa Loa (eye worm) RecQ helicase 0.0021 0.0032 0.0064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0045
Leishmania major phosphatidylinositol kinase, putative 0.007 0.0259 0.0697
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0045
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.005 0.0169 0.0453
Brugia malayi intermediate filament protein 0.0026 0.0057 0.0159
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0024 0.0047 0.0084
Leishmania major phosphatidylinositol kinase related protein, putative 0.0084 0.0327 0.0878
Echinococcus multilocularis survival motor neuron protein 1 0.0466 0.2097 0.2097
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0023 0.0022
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0343 0.1527 0.1527
Loa Loa (eye worm) phosphatidylinositol 3 0.0265 0.1166 0.2359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0209 0.0906 0.2464
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0132 0.0549 0.1111
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0155 0.0654 0.181
Giardia lamblia Kinase, CMGC GSK 0.005 0.0169 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0397 0.1045
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0023 0.0022
Entamoeba histolytica hypothetical protein 0.0036 0.01 0.0215
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0093 0.0366 0.1015
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0265 0.1166 0.7631
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0023 0.0022
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0298 0.1317 0.3649
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Brugia malayi Protein kinase domain containing protein 0.0018 0.0016 0.0045
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0171 0.0728 0.0728
Loa Loa (eye worm) hypoxia-induced factor 1 0.0149 0.0626 0.1267
Giardia lamblia GTOR 0.0343 0.1527 0.768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.1243 0.3402
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0103 0.1533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.1369 0.3754
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0434 0.1146
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0343 0.1527 0.4196
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0023 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0001 0.0002
Brugia malayi Cytochrome P450 family protein 0.0029 0.0071 0.0197
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.007 0.0259 0.3873
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0047 0.0084
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.01 0.0397 0.0397
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0069 0.1034
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0298 0.1317 0.8622
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0038 0.0038
Leishmania major hypothetical protein, conserved 0.0022 0.0036 0.0095
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0023 0.0063
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0158 0.0669 0.1803
Brugia malayi hypothetical protein 0.0019 0.0023 0.0063
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.01 0.0099
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0065 0.0065
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0023 0.0045
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.007 0.0259 0.0463
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0041 0.0126 0.0346
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0032 0.0025
Echinococcus multilocularis cyclin dependent kinase 19 0.0132 0.0549 0.0548
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0158 0.0282
Echinococcus multilocularis musashi 0.0026 0.0057 0.0057
Toxoplasma gondii FATC domain-containing protein 0.0169 0.0721 0.5264
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0557 0.2519 0.2519
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0045 0.0143 0.0396
Giardia lamblia Casein kinase II beta chain 0.0036 0.0103 0.0176
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.019 0.0815 0.0814
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0177 0.0755 0.2093
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0158 0.0669 0.0669
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0082 0.0081
Echinococcus granulosus survival motor neuron protein 1 0.0466 0.2097 0.2097
Brugia malayi Uncoordinated protein 44 0.0014 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0024
Schistosoma mansoni hypothetical protein 0.01 0.0397 0.071
Loa Loa (eye worm) hypothetical protein 0.0155 0.0654 0.1323
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0058 0.01
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0318 0.141 0.2853
Loa Loa (eye worm) Csnk2b protein 0.0036 0.0103 0.0207
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0024 0.0352
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0023 0.0063
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0023 0.0045
Schistosoma mansoni protein kinase 0.0135 0.0563 0.1007
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0155 0.0654 0.0653
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0158 0.0669 0.0669
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0434 0.1146
Loa Loa (eye worm) phosphatidylinositol 3 0.007 0.0259 0.0524
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0434 0.1146
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0008 0.0021
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0791 0.3609 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0069 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0169 0.0407
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0038 0.0076
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0158 0.0669 0.1854
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0265 0.1166 0.3187
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1401 0.3843
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0032 0.0082 0.0081
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0273 0.0272
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0376 0.1041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1401 0.3843
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0298 0.1317 0.3609
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Brugia malayi Serotonin receptor 0.0461 0.2076 0.5753
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0438 0.1968 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0155 0.0654 0.176
Toxoplasma gondii CMGC kinase, CK2 family 0.0135 0.0563 0.4113
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.005 0.0169 0.0168
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.007 0.0259 0.189
Loa Loa (eye worm) phosphatidylinositol 3 0.007 0.0259 0.0524
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0038 0.0067
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0008 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0815 0.2209
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0304 0.1347 0.3732
Entamoeba histolytica casein kinase, putative 0.0135 0.0563 0.1508
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1013 0.2762
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0434 0.0433
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0058 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0231 0.1006 0.2743
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.1369 0.3754
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0158 0.0669 0.1853
Loa Loa (eye worm) hypothetical protein 0.0027 0.0061 0.0122
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.0024 0.0536
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0577 0.2616 0.723
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0001 0.0001
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0273 0.0272
Schistosoma mansoni hypothetical protein 0.0161 0.0682 0.122
Schistosoma mansoni hypothetical protein 0.0051 0.017 0.0303
Entamoeba histolytica hypothetical protein 0.0036 0.01 0.0215
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.007 0.0259 0.0717
Trypanosoma brucei PAB1-binding protein , putative 0.0022 0.0036 0.0231
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0434 0.1146
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0069 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0085 0.0329 0.0854
Echinococcus granulosus voltage dependent calcium channel 0.0032 0.0082 0.0081
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.004 0.007
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0298 0.1317 0.3648
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.007 0.0259 0.0717
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0058 0.01
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.007 0.0259 0.0718
Echinococcus multilocularis lamin dm0 0.0026 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0215 0.0536
Leishmania major phosphatidylinositol 3-kinase, putative 0.0255 0.1116 0.3006
Plasmodium vivax glycogen synthase kinase 3, putative 0.005 0.0169 0.2518
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0024 0.0007
Trypanosoma brucei protein kinase, putative 0.005 0.0169 0.1101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.007 0.0125
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0032 0.0082 0.0227
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0045 0.0143 0.0289
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0045
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0008 0.0021
Echinococcus granulosus serine protein kinase ATM 0.0169 0.0721 0.072
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0023 0.0022
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0032 0.0082 0.0081
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0318 0.141 0.3906
Loa Loa (eye worm) hypothetical protein 0.0099 0.0396 0.0801
Echinococcus granulosus single minded 2 0.0036 0.01 0.0099
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0426 0.1914 0.5302
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0169 0.0721 0.1289
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.01 0.0178
Loa Loa (eye worm) hypothetical protein 0.0046 0.0149 0.03
Schistosoma mansoni tar DNA-binding protein 0.0057 0.0199 0.0356
Loa Loa (eye worm) hypothetical protein 0.0069 0.0254 0.0513
Plasmodium falciparum phosphatidylinositol 4-kinase 0.007 0.0259 0.3869
Brugia malayi Isocitrate dehydrogenase 0.0014 0.0001 0.0002
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1218 0.5588 1
Schistosoma mansoni intermediate filament proteins 0.0026 0.0057 0.0102
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0 0.0001
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0099 0.0396 0.1096
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0058 0.0162
Brugia malayi Calcitonin receptor-like protein seb-1 0.0045 0.0143 0.0396
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0343 0.1527 0.4231
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0048
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0434 1
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0434 0.1146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1527 0.4196
Onchocerca volvulus 0.0026 0.0057 0.0403
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.018 0.044
Brugia malayi hypothetical protein 0.0099 0.0396 0.1098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1527 0.4196
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.01 0.0397 0.0397
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0158 0.0669 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.1369 0.3754
Plasmodium vivax hypothetical protein, conserved 0.007 0.0259 0.3873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0169 0.0721 0.1947
Trichomonas vaginalis PIKK family atypical protein kinase 0.0209 0.0906 0.2464
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0815 0.2209
Toxoplasma gondii target of rapamycin (TOR), putative 0.0309 0.1369 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.007 0.007
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0169 0.0721 0.4718
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0815 0.2209
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0023 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0563 0.1508
Brugia malayi FAT domain containing protein 0.01 0.0397 0.1101
Brugia malayi Cytochrome P450 family protein 0.0019 0.0024 0.0065
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0158 0.0669 0.1197
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0071 0.0143
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0304 0.1347 0.3732
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.1369 0.3754
Mycobacterium leprae conserved hypothetical protein 0.007 0.0259 0.5744
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0652 0.2961 0.8194
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0038 0.0106
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.019 0.0815 0.1649
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0069 0.0131
Loa Loa (eye worm) hypothetical protein 0.0099 0.0396 0.0801
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0158 0.0669 0.4886
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0209 0.0907 0.4413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0209 0.0906 0.2464
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.004 0.007
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.005 0.0169 0.1228
Brugia malayi hypothetical protein 0.0019 0.0023 0.0063
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0135 0.0563 0.842
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0343 0.1527 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0058 0.01
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.007 0.0259 0.0259
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Schistosoma mansoni tar DNA-binding protein 0.0057 0.0199 0.0356
Loa Loa (eye worm) hypothetical protein 0.01 0.0397 0.0804
Leishmania major protein kinase, putative 0.0016 0.0008 0.002
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0024 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0343 0.1527 0.4231
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0111
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0343 0.1527 1
Onchocerca volvulus 0.0232 0.1014 0.7189
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0815 0.2209
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0318 0.141 0.2853
Entamoeba histolytica hypothetical protein 0.0036 0.01 0.0215
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0069 0.1029
Trypanosoma cruzi PAB1-binding protein , putative 0.0022 0.0036 0.0098
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0559 0.253 0.7009
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0069 0.1029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.01 0.0099
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0047 0.0152 0.0272
Echinococcus granulosus serine:threonine protein kinase PLK1 0.019 0.0815 0.0814
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0023 0.0039
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0343 0.1527 0.4232
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0023 0.0022
Entamoeba histolytica hypothetical protein 0.007 0.0259 0.066
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.007 0.0125
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0082 0.0081
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0372 0.1663 0.4573
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0039
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0343 0.1527 0.4113
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0434 0.0433
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.007 0.0259 0.0463
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0038 0.0076
Schistosoma mansoni casein kinase II beta subunit 0.0036 0.0103 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1401 0.3843
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.1275 0.3492
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.007 0.0259 0.1694
Loa Loa (eye worm) hypothetical protein 0.0045 0.0143 0.0289
Schistosoma mansoni single-minded 0.0048 0.0158 0.0282
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0036 0.0103 0.0725
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0791 0.3609 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0434 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0162 0.0327
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0169 0.0341
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.007 0.0259 0.0259
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0215 0.0536
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0169 0.0407
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0103 0.0283
Echinococcus granulosus casein kinase ii subunit alpha 0.0135 0.0563 0.0563
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.007 0.0259 0.1694
Loa Loa (eye worm) hypothetical protein 0.007 0.0261 0.0528
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0023 0.0022
Plasmodium vivax SET domain protein, putative 0.0029 0.007 0.105
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0434 0.12
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0434 0.0877
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0158 0.0669 0.0669
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0023 0.0063
Plasmodium falciparum ataxin-2 like protein, putative 0.0022 0.0036 0.0528
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0557 0.2519 0.2519
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0029 0.0058
Echinococcus multilocularis tar DNA binding protein 0.0057 0.0199 0.0199
Schistosoma mansoni hypothetical protein 0.0036 0.01 0.0178
Leishmania major protein kinase, putative 0.0016 0.0008 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.007 0.007
Plasmodium falciparum glycogen synthase kinase 3 0.005 0.0169 0.2513
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0563 0.1508
Loa Loa (eye worm) phosphatidylinositol 3 0.007 0.0259 0.0524
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.004 0.007
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Brugia malayi peptidase family M13 containing protein 0.0023 0.004 0.011
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0563 0.1508
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.0259 0.5972
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0038 0.0038
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0158 0.0669 0.4886
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Mycobacterium ulcerans zinc metalloprotease 0.0093 0.0366 0.8359
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Loa Loa (eye worm) hypothetical protein 0.0032 0.0082 0.0165
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.007 0.0259 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0259 0.066
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0791 0.3609 1
Onchocerca volvulus 0.0049 0.0162 0.1143
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0169 0.0721 0.1997
Schistosoma mansoni survival motor neuron protein 0.0095 0.0376 0.0671
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0023 0.0039
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Onchocerca volvulus 0.0036 0.01 0.0705
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0008 0.0021
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0084 0.0327 0.0903
Onchocerca volvulus 0.0046 0.0149 0.105
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0023 0.0022
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0197 0.0849 0.5554
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0169 0.0407
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0024 0.0064
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0434 0.2837
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0343 0.1527 0.4196
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0057 0.0115
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0057 0.0199 0.0403
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0023 0.0039
Brugia malayi bHLH-PAS transcription factor 0.0036 0.01 0.0277
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.007 0.0259 0.0718
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0791 0.3609 1
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0318 0.141 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0027 0.0058 0.0162
Onchocerca volvulus Serine\/threonine kinase homolog 0.019 0.0815 0.5778
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.1242 0.3401
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0255 0.1116 0.7308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1401 0.3843
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.1243 0.3402
Mycobacterium ulcerans putative regulatory protein 0.0036 0.01 0.1861
Brugia malayi 6-phosphofructokinase 0.0107 0.0434 0.1202
Echinococcus granulosus lamin 0.0026 0.0057 0.0057
Schistosoma mansoni kinase 0.0098 0.0388 0.0694
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0563 0.1508
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0047 0.0152 0.0272
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.007 0.0259 0.0717
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0093 0.0366 0.0655
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0316 0.1401 0.3774
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0024 0.0047
Onchocerca volvulus 0.0095 0.0376 0.2662
Loa Loa (eye worm) hypothetical protein 0.0093 0.0366 0.0741
Loa Loa (eye worm) hypothetical protein 0.007 0.0261 0.0528
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0023 0.0063
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0215 0.0536
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.1116 0.305
Loa Loa (eye worm) hypothetical protein 0.007 0.0261 0.0528
Echinococcus multilocularis geminin 0.0166 0.0706 0.0706
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0024 0.015
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0036 0.0103 0.0283
Toxoplasma gondii non-specific serine/threonine protein kinase 0.017 0.0722 0.5272
Loa Loa (eye worm) hypothetical protein 0.0671 0.305 0.6174
Echinococcus multilocularis casein kinase ii subunit beta 0.0036 0.0103 0.0102
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.019 0.0815 0.2194
Schistosoma mansoni hypothetical protein 0.0024 0.0047 0.0084
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.007 0.0259 0.3869
Trypanosoma cruzi casein kinase II, putative 0.0135 0.0563 0.156
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0024 0.017
Giardia lamblia Kinase, PLK 0.019 0.0815 0.3927
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.006 0.0215 0.0214
Brugia malayi hypothetical protein 0.0036 0.01 0.0277
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0036 0.0103 0.0747
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0155 0.0654 0.0653
Brugia malayi serine/threonine-protein kinase plk-2 0.019 0.0815 0.2258
Brugia malayi Angiotensin-converting enzyme family protein 0.0611 0.277 0.7674
Loa Loa (eye worm) hypothetical protein 0.0069 0.0254 0.0513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.1242 0.3401
Loa Loa (eye worm) hypothetical protein 0.0557 0.2519 0.5098
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0343 0.1526 0.4191
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.002 0.0289
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0024 0.0347
Trypanosoma cruzi target of rapamycin kinase 3 0.0316 0.1401 0.3882
Entamoeba histolytica hypothetical protein 0.007 0.0259 0.066
Trypanosoma cruzi hypothetical protein, conserved 0.0744 0.3388 0.9386
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0329 0.0854
Schistosoma mansoni fkbp-rapamycin associated protein 0.0155 0.0654 0.1169
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0434 0.0775
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0023 0.0063
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0304 0.1347 0.241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.1242 0.3401
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0434 0.0877
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0024 0.0064
Brugia malayi RNA binding protein 0.0057 0.0199 0.0553
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0158 0.0669 0.1853
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0162 0.0288
Loa Loa (eye worm) hypothetical protein 0.007 0.0261 0.0528
Loa Loa (eye worm) hypothetical protein 0.0069 0.0254 0.0513
Echinococcus multilocularis expressed protein 0.0369 0.1649 0.1648
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0298 0.1317 0.3609
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0563 0.1508
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.1116 0.305
Plasmodium falciparum casein kinase II beta chain 0.0036 0.0103 0.1528
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0882 0.1785
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0563 0.1508
Brugia malayi hypothetical protein 0.0161 0.0684 0.1895
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0343 0.1527 0.2732
Schistosoma mansoni voltage-gated cation channel 0.0032 0.0082 0.0145
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0069 0.0503
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0215 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0549 0.0982
Loa Loa (eye worm) calcium channel 0.0032 0.0082 0.0165
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0318 0.141 0.1409
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.007 0.0259 0.0259
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0103 0.0224
Echinococcus granulosus bloom syndrome protein 0.0021 0.0032 0.0031
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0316 0.1401 0.9175
Brugia malayi M-phase phosphoprotein, mpp8 0.0099 0.0396 0.1096
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0434 0.1146
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0041 0.0126 0.0287
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0039
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0434 0.1167
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0023 0.0022
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0169 0.0721 0.1996
Echinococcus multilocularis casein kinase ii subunit alpha 0.0135 0.0563 0.0563
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0228 0.0992 0.2748
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Mycobacterium leprae probable zinc metalloprotease 0.0093 0.0366 0.8358
Loa Loa (eye worm) hypothetical protein 0.0161 0.0684 0.1384
Echinococcus granulosus endothelin converting enzyme 1 0.0093 0.0366 0.0366
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0343 0.1527 0.4113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.1369 0.3754
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.007 0.0259 0.0259
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1218 0.5588 0.5588
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0069 0.0131
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0069 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.1369 0.3754
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.007 0.0125
Toxoplasma gondii ck2 beta subunit 0.0036 0.0103 0.0747
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0158 0.0669 0.1803
Echinococcus multilocularis endothelin converting enzyme 1 0.0093 0.0366 0.0366
Loa Loa (eye worm) phosphatidylinositol 3 0.007 0.0259 0.0524
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0103 0.0224
Plasmodium vivax casein kinase II beta chain, putative 0.0036 0.0103 0.1533
Brugia malayi hypothetical protein 0.0466 0.2097 0.5811
Leishmania major hypothetical protein, unknown function 0.007 0.0259 0.0697
Toxoplasma gondii hypothetical protein 0.0019 0.0024 0.017
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0791 0.3609 1
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0023 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.1116 0.305
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0032 0.0025
Leishmania major cytochrome p450-like protein 0.0019 0.0024 0.0062
Echinococcus granulosus cyclin dependent kinase 19 0.0132 0.0549 0.0548
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0265 0.1166 0.3139
Echinococcus multilocularis protein kinase shaggy 0.005 0.0169 0.0168
Schistosoma mansoni phosphatidylinositol 4-kinase 0.007 0.0259 0.0463
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0069 0.0131
Onchocerca volvulus 0.007 0.0259 0.1836
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Plasmodium vivax unspecified product 0.0135 0.0563 0.842
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.007 0.0259 0.3873
Schistosoma mansoni hypothetical protein 0.0166 0.0706 0.1263
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0023 0.0022
Brugia malayi isocitrate dehydrogenase 0.0014 0.0001 0.0002
Brugia malayi PXA domain containing protein 0.002 0.0029 0.0081
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0158 0.0669 0.4379
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0169 0.0407
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0023 0.0022
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.007 0.0259 0.189
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.004 0.007
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0298 0.1317 0.3609
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0169 0.0341
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0158 0.0669 0.1197
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Brugia malayi Csnk2b protein 0.0036 0.0103 0.0285
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.006 0.0215 0.0383
Brugia malayi latrophilin 2 splice variant baaae 0.0031 0.0077 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.1243 0.3402
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0027 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0466 0.2097 0.4245
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0001 0.000006204
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Brugia malayi intracellular kinase 0.005 0.0169 0.0467
Loa Loa (eye worm) TAR-binding protein 0.0057 0.0199 0.0403
Loa Loa (eye worm) phosphatidylinositol 3 0.0343 0.1527 0.3091
Leishmania major phosphatidylinositol 3-kinase, putative 0.0158 0.0669 0.1801
Echinococcus granulosus high voltage activated calcium channel beta 0.0086 0.0333 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0024 0.0003
Plasmodium falciparum casein kinase 2, alpha subunit 0.0135 0.0563 0.8419
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.1527 0.4196
Echinococcus multilocularis tumor protein p63 0.0334 0.1486 0.1486
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0304 0.1347 0.3733
Leishmania major phosphatidylinositol 4-kinase, putative 0.007 0.0259 0.0697
Loa Loa (eye worm) hypothetical protein 0.0029 0.007 0.0142
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.007 0.051
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0023 0.0022
Entamoeba histolytica hypothetical protein 0.0169 0.0721 0.1947
Loa Loa (eye worm) isocitrate dehydrogenase 0.0014 0.0001 0.0001
Onchocerca volvulus 0.004 0.0122 0.0864
Schistosoma mansoni lamin 0.0026 0.0057 0.0102
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Plasmodium vivax ataxin-2 like protein, putative 0.0022 0.0036 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0316 0.1401 0.3843
Trypanosoma cruzi PAB1-binding protein , putative 0.0022 0.0036 0.0098
Trichomonas vaginalis CMGC family protein kinase 0.0135 0.0563 0.1508
Loa Loa (eye worm) phosphatidylinositol kinase 0.007 0.0259 0.0524
Loa Loa (eye worm) hypothetical protein 0.007 0.0261 0.0528
Schistosoma mansoni hypothetical protein 0.0024 0.0047 0.0084
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.005 0.0169 0.0466
Loa Loa (eye worm) hypothetical protein 0.0099 0.0396 0.08
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0041 0.0126 0.0287
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0093 0.0366 0.8446
Echinococcus multilocularis lamin 0.0026 0.0057 0.0057
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0135 0.0563 0.114
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0434 0.0877
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0057 0.0159
Echinococcus granulosus death domain containing protein 0.0014 0.0001 0.000006204
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0122 0.0218
Loa Loa (eye worm) hypothetical protein 0.007 0.0259 0.0524
Echinococcus granulosus intermediate filament protein 0.0026 0.0057 0.0057
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0344 0.0614
Leishmania major casein kinase II, putative 0.0135 0.0563 0.1516
Brugia malayi 6-phosphofructokinase 0.0107 0.0434 0.1202
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0177 0.0755 0.1529
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0155
Schistosoma mansoni hypothetical protein 0.0024 0.0047 0.0084
Entamoeba histolytica protein kinase, putative 0.005 0.0169 0.0407
Trichomonas vaginalis CAMK family protein kinase 0.019 0.0815 0.2209
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0215 0.0536
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0158 0.0669 0.1803
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0072
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0036 0.0103 0.0224
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0215 0.1403
Onchocerca volvulus 0.0026 0.0057 0.0403
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0215 0.0536
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0434 0.0775
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0802 0.3659 0.3658
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0216 0.0938 0.2553
Echinococcus granulosus protein kinase shaggy 0.005 0.0169 0.0168
Brugia malayi follicle stimulating hormone receptor 0.0234 0.102 0.2826
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0434 1
Trypanosoma brucei polo-like protein kinase 0.019 0.0815 0.5333
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0215 0.0593
Echinococcus granulosus casein kinase ii subunit beta 0.0036 0.0103 0.0102
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0577 0.2616 0.723
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.0024 0.0536
Schistosoma mansoni hypothetical protein 0.0024 0.0047 0.0084
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0038 0.0067
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.007 0.0259 0.189
Brugia malayi PAS domain containing protein 0.0048 0.0158 0.0438
Brugia malayi Pre-SET motif family protein 0.0204 0.0882 0.2444
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0032 0.0082 0.0145
Echinococcus granulosus tumor protein p63 0.0334 0.1486 0.1486
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0377 0.0987
Toxoplasma gondii hypothetical protein 0.0053 0.018 0.1313
Loa Loa (eye worm) phosphatidylinositol 3 0.1078 0.494 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0165 0.0703 0.1897
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0032 0.0082 0.0081
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0069 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.1116 0.305
Loa Loa (eye worm) hypothetical protein 0.0027 0.0058 0.0117
Brugia malayi Pre-SET motif family protein 0.0029 0.007 0.0195
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0158 0.0669 0.1803
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0611 0.277 0.5606
Echinococcus multilocularis Zinc finger, PHD finger 0.0158 0.0669 0.0669
Schistosoma mansoni hypothetical protein 0.007 0.0259 0.0463
Brugia malayi phosphofructokinase 0.0107 0.0434 0.1202
Giardia lamblia Kinase, CMGC GSK 0.005 0.0169 0.0523
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0086 0.0333 0.0595
Giardia lamblia Kinase, CMGC CK2 0.0135 0.0563 0.2602
Entamoeba histolytica hypothetical protein 0.0036 0.01 0.0215
Echinococcus granulosus lamin dm0 0.0026 0.0057 0.0057
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0721 0.3284 0.9095
Echinococcus multilocularis voltage dependent calcium channel 0.0032 0.0082 0.0081
Onchocerca volvulus 0.007 0.0259 0.1836
Brugia malayi RNA recognition motif domain containing protein 0.0057 0.0199 0.0553
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0045
Brugia malayi Cytochrome P450 family protein 0.0019 0.0024 0.0065
Echinococcus granulosus expressed protein 0.0369 0.1649 0.1648
Onchocerca volvulus 0.005 0.0169 0.1193
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.2168 1 1
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0344 0.0343
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0155 0.0654 0.1811
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0124 0.0512 0.3348
Trichomonas vaginalis casein kinase II beta chain, putative 0.0036 0.0103 0.0224
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0023 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0243 0.1065 0.2905
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0038 0.0067
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0039
Loa Loa (eye worm) peptidase family M13 containing protein 0.0069 0.0254 0.0513
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0000062211
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0344 0.0614
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0215 0.0593
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0032 0.0082 0.0081
Onchocerca volvulus 0.0099 0.0396 0.2804
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0057 0.0115
Loa Loa (eye worm) gastrulation defective protein 1 0.0129 0.0533 0.1079
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0434 0.1146
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.017 0.0722 0.1461

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1 Antifertility effect of the compound was tested in adult female rats by estrus suppression assay ChEMBL. 6366232

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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