Detailed information for compound 506535

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 490.465 | Formula: C26H33Cl2N3O2
  • H donors: 1 H acceptors: 1 LogP: 4.63 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C[C@@H](c1cc(Cl)ccc1N1CCN(CC1)C(=O)[C@H]1CCO[C@@H]1c1ccc(cc1)Cl)N)C
  • InChi: 1S/C26H33Cl2N3O2/c1-17(2)15-23(29)22-16-20(28)7-8-24(22)30-10-12-31(13-11-30)26(32)21-9-14-33-25(21)18-3-5-19(27)6-4-18/h3-8,16-17,21,23,25H,9-15,29H2,1-2H3/t21-,23-,25+/m0/s1
  • InChiKey: OVNHRYAPFAJXCA-UMXIMWEHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens melanocortin 4 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0129 0.1238 0.2009
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0082 0.0105
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0082 0.0123
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0148 0.1672
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0414 0.069
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0248 0.2491 0.417
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0575 0.5919 1
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0579 0.056
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.03 0.4615
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0672 0.1135
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0079 0.0101
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0248 0.2491 0.4172
Brugia malayi Dihydrofolate reductase 0.0125 0.1199 0.2007
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0118 0.0173
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0579 0.0889
Onchocerca volvulus 0.0019 0.0082 0.0123
Schistosoma mansoni lamin 0.006 0.0512 0.0775
Plasmodium falciparum thioredoxin reductase 0.0049 0.0399 0.0645
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0433 0.4426 0.7471
Loa Loa (eye worm) hypothetical protein 0.0059 0.0497 0.0815
Brugia malayi glutathione reductase 0.0049 0.0399 0.0653
Loa Loa (eye worm) hypothetical protein 0.0169 0.1659 0.2784
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.002 0.0033
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.0338 0.5349
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0399 0.065
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0061 0.0093
Brugia malayi intermediate filament protein 0.006 0.0512 0.0844
Schistosoma mansoni heat shock protein 0.0025 0.0148 0.0154
Echinococcus granulosus g protein coupled receptor 0.0019 0.0082 0.0105
Mycobacterium ulcerans heat shock protein 90 0.0029 0.0187 0.029
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.002 0.0033
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0248 0.0359
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.1238 0.2084
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0043 0.0338 0.054
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0023 0.0122 0.0196
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0575 0.5919 1
Trichomonas vaginalis rotamase, putative 0.0034 0.0239 0.0394
Schistosoma mansoni neuropeptide receptor 0.0019 0.0082 0.0041
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0023 0.0124 0.0182
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0023 0.0123 0.0175
Echinococcus granulosus neuropeptide receptor 0.0019 0.0082 0.0105
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.03 0.0475
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0705 0.1191
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0079 0.0036
Echinococcus granulosus peter pan 0.0061 0.052 0.0848
Onchocerca volvulus 0.0019 0.0082 0.0123
Plasmodium vivax hypothetical protein, conserved 0.0061 0.052 0.0818
Brugia malayi RE15519p 0.0019 0.0082 0.0115
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0066 0.0579 0.0978
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Schistosoma mansoni single-minded 0.005 0.0412 0.0604
Mycobacterium ulcerans 6-phosphofructokinase 0.0129 0.1238 0.2071
Loa Loa (eye worm) thymidylate synthase 0.0123 0.1174 0.1962
Brugia malayi acetyltransferase, GNAT family protein 0.0172 0.169 0.284
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0399 0.0675
Echinococcus multilocularis serotonin receptor 0.0019 0.0082 0.0062
Plasmodium falciparum acyl-CoA synthetase 0.0059 0.0497 0.081
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Onchocerca volvulus 0.0023 0.0124 0.0206
Plasmodium vivax heat shock protein, putative 0.0017 0.0058 0.0032
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0082 0.0062
Loa Loa (eye worm) hypothetical protein 0.0022 0.0118 0.0173
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0082 0.0062
Loa Loa (eye worm) hypothetical protein 0.0059 0.0497 0.0815
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1238 0.2084
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0061 0.0104
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.03 0.0485
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.1238 0.2084
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0019 0.0021
Plasmodium falciparum BRIX domain, putative 0.0061 0.052 0.0849
Loa Loa (eye worm) heat shock protein 75 0.0017 0.0058 0.0071
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.022 0.0349
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.002 0.0023
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0023 0.0124 0.0106
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.0339 0.032
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0029 0.0187 0.0214
Onchocerca volvulus 0.0022 0.0118 0.0195
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0079 0.0068
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0079 0.0102
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0066 0.0579 0.0949
Toxoplasma gondii heat shock protein 75, putative 0.0017 0.0058 0.0035
Echinococcus granulosus endoplasmin 0.0029 0.0187 0.0284
Schistosoma mansoni amine GPCR 0.0019 0.0082 0.0041
Echinococcus multilocularis musashi 0.006 0.0512 0.0493
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0075 0.0672 0.0653
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0082 0.0105
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0079 0.011
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0016 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.1238 0.2014
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0062 0.0534 0.0877
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0061 0.0104
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0061 0.0104
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.002 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0082 0.0105
Loa Loa (eye worm) hypothetical protein 0.0059 0.0501 0.0821
Echinococcus granulosus lamin dm0 0.006 0.0512 0.0835
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0082 0.0105
Echinococcus multilocularis 6 phosphofructokinase 0.0129 0.1238 0.1221
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0248 0.0389
Entamoeba histolytica hypothetical protein 0.0019 0.0079 0.0123
Loa Loa (eye worm) brix domain-containing protein 0.0061 0.052 0.0854
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0029 0.0187 0.0316
Schistosoma mansoni adenosylhomocysteinase 0.0356 0.3618 0.6074
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0082 0.0111
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0082 0.0123
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1238 0.2084
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0082 0.0062
Plasmodium falciparum heat shock protein 90, putative 0.0017 0.0058 0.0066
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0079 0.0107
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0118 0.0098
Echinococcus granulosus lamin 0.006 0.0512 0.0835
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0043 0.0338 0.0562
Schistosoma mansoni 23-cyclic-nucleotide 2-phosphodiesterase 0.0136 0.1306 0.2129
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0082 0.0062
Echinococcus granulosus hypothetical protein 0.0019 0.0082 0.0105
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0066 0.0579 0.0978
Leishmania major ATP-dependent phosphofructokinase 0.0129 0.1238 0.2092
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0239 0.0404
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0239 0.0404
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0248 0.041
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0082 0.0105
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0248 0.2491 0.4208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Onchocerca volvulus 0.0019 0.0082 0.0123
Echinococcus multilocularis heat shock protein 90 0.0025 0.0148 0.0128
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0082 0.0115
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0082 0.0062
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0186 0.0167
Echinococcus granulosus tar DNA binding protein 0.0075 0.0672 0.1107
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0078 0.0705 0.1167
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0082 0.0105
Schistosoma mansoni P2X receptor subunit 0.0334 0.3391 0.5687
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0082 0.0062
Brugia malayi PXA domain containing protein 0.0019 0.0079 0.011
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0023 0.0124 0.0182
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0082 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0082 0.0105
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0082 0.0115
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0575 0.5919 1
Brugia malayi hypothetical protein 0.0019 0.0079 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Brugia malayi GnHR receptor homolog 0.0019 0.0082 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0463 0.0686
Brugia malayi PXA domain containing protein 0.0019 0.0079 0.011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0534 0.0812
Echinococcus granulosus p2X purinoceptor 4 0.0334 0.3391 0.5715
Schistosoma mansoni endoplasmin 0.0025 0.0148 0.0154
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0061 0.0353
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Toxoplasma gondii brix domain-containing protein 0.0061 0.052 0.0821
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0248 0.041
Onchocerca volvulus 0.0062 0.0534 0.1021
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0061 0.0093
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0134 0.1293 0.2158
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.1238 0.2084
Onchocerca volvulus 0.0019 0.0082 0.0123
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0123 0.1174 0.1957
Schistosoma mansoni polycystin 1-related 0.0022 0.0118 0.0102
Trypanosoma brucei heat shock protein 84, putative 0.0017 0.0058 0.0087
Entamoeba histolytica heat shock protein 90, putative 0.0025 0.0148 0.024
Trichomonas vaginalis ap endonuclease, putative 0.004 0.03 0.0497
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0248 0.0356
Brugia malayi Melatonin receptor type 1A 0.0019 0.0082 0.0115
Plasmodium falciparum thioredoxin reductase 0.0017 0.0061 0.0072
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0579 0.056
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0082 0.0062
Schistosoma mansoni adenosylhomocysteinase 0.0575 0.5919 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0078 0.0705 0.1167
Loa Loa (eye worm) heat shock protein 90 0.0025 0.0148 0.0223
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0075 0.0672 0.1105
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0079 0.0059
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0575 0.5919 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0107
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0148 0.025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0067 0.0087
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0079 0.006
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0082 0.0105
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0148 0.025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0463 0.0686
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0023 0.0124 0.0186
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0274 0.0437
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0705 0.1162
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0082 0.0062
Onchocerca volvulus Peter pan protein homolog 0.0061 0.052 0.0994
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0082 0.0041
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0114 0.0183
Brugia malayi hypoxia-induced factor 1 0.0156 0.1521 0.2553
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0079 0.0036
Brugia malayi Doublecortin family protein 0.0022 0.0118 0.0176
Toxoplasma gondii heat shock protein 90, putative 0.0025 0.0148 0.0188
Brugia malayi Serotonin receptor 0.0019 0.0082 0.0115
Schistosoma mansoni amine GPCR 0.0019 0.0082 0.0041
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.002 0.0033
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0079 0.0107
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0534 0.0871
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0534 0.0812
Onchocerca volvulus 0.0019 0.0082 0.0123
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0016 0.0027
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0705 0.1167
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0023 0.0124 0.0176
Echinococcus multilocularis p2X purinoceptor 4 0.0334 0.3391 0.3378
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus granulosus tumor protein p63 0.035 0.3561 0.6004
Onchocerca volvulus 0.0019 0.0082 0.0123
Brugia malayi sulfakinin receptor protein 0.0019 0.0082 0.0115
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0046 0.0363 0.0588
Schistosoma mansoni P2X receptor subunit 0.0199 0.1973 0.3268
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0019 0.0021
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.002 0.0033
Echinococcus granulosus zinc finger protein 598 0.006 0.0516 0.0841
Loa Loa (eye worm) TAR-binding protein 0.0075 0.0672 0.1112
Leishmania major acetyl-CoA synthetase, putative 0.0023 0.0124 0.0209
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0066 0.0579 0.0978
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0079 0.01
Schistosoma mansoni adenosylhomocysteinase 0.0356 0.3618 0.6074
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0061 0.0042
Echinococcus multilocularis lamin 0.006 0.0512 0.0493
Brugia malayi phosphofructokinase 0.0129 0.1238 0.2074
Schistosoma mansoni neuropeptide receptor 0.0019 0.0082 0.0041
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0414 0.064
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0399 0.038
Toxoplasma gondii exonuclease III APE 0.004 0.03 0.0447
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0672 0.1125
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0066 0.0579 0.0921
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0098 0.0165
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0118 0.0166
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0061 0.0093
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0079 0.003
Entamoeba histolytica brix domain containing protein 0.0061 0.052 0.0869
Plasmodium vivax acetyl-CoA synthetase, putative 0.0023 0.0124 0.0144
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0239 0.0343
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0399 0.0613
Echinococcus multilocularis peter pan 0.0061 0.052 0.0501
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0672 0.1049
Toxoplasma gondii 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.031 0.3134 0.5266
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0079 0.011
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0579 0.0948
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0061 0.0104
Brugia malayi Hsp90 protein 0.0017 0.0058 0.0075
Echinococcus granulosus heat shock protein 90 0.0025 0.0148 0.0217
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0079 0.0059
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0575 0.5919 1
Trypanosoma brucei brix domain containing protein, putative 0.0061 0.052 0.0869
Toxoplasma gondii 5'-nucleotidase, C-terminal domain-containing protein 0.0056 0.0468 0.0733
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0082 0.0105
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0918
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.002 0.0023
Trichomonas vaginalis antibiotic synthetase, putative 0.0023 0.0124 0.0199
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.1062 0.1767
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0082 0.0115
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0148 0.1672
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0059 0.0497 0.0815
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0059 0.0497 0.0744
Schistosoma mansoni neuropeptide receptor 0.0019 0.0082 0.0041
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0575 0.5919 1
Onchocerca volvulus 0.0051 0.0421 0.0796
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0248 0.041
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0082 0.0105
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0078 0.0705 0.1099
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0061 0.0072
Leishmania major acetyl-CoA synthetase, putative 0.0023 0.0124 0.0209
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0061 0.0081
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0082 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0023 0.0124 0.0199
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0534 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0079 0.0123
Schistosoma mansoni amine GPCR 0.0019 0.0082 0.0041
Entamoeba histolytica acyl-CoA synthetase, putative 0.0078 0.0705 0.1182
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0082 0.0062
Entamoeba histolytica adenosylhomocysteinase, putative 0.0575 0.5919 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0029 0.0187 0.2428
Loa Loa (eye worm) hypothetical protein 0.0028 0.0175 0.0269
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Trichomonas vaginalis conserved hypothetical protein 0.031 0.3134 0.5291
Leishmania major cytochrome p450-like protein 0.0013 0.0016 0.0027
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0061 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0079 0.0123
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0125 0.1199 0.2004
Toxoplasma gondii adenosylhomocysteinase, putative 0.0575 0.5919 1
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Leishmania major protein kinase, putative 0.0013 0.002 0.0033
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0079 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.1062 0.1709
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0075 0.0672 0.1111
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0672 0.1049
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0124 0.0186
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0124 0.0106
Trichomonas vaginalis adenosylhomocysteinase, putative 0.018 0.1777 0.2995
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0978
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0079 0.0123
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0274 0.0255
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0114 0.0183
Echinococcus multilocularis p2X purinoceptor 4 0.0334 0.3391 0.3378
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Plasmodium vivax glutathione reductase, putative 0.0049 0.0399 0.0613
Loa Loa (eye worm) hypothetical protein 0.0023 0.0124 0.0182
Plasmodium vivax endoplasmin, putative 0.0025 0.0148 0.0185
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0082 0.0062
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0124 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0463 0.0686
Loa Loa (eye worm) oxidoreductase 0.0023 0.0124 0.0182
Echinococcus granulosus expressed protein 0.0035 0.0248 0.0386
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0059 0.0497 0.0839
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Leishmania major protein kinase, putative 0.0013 0.002 0.0033
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0066 0.0579 0.0957
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0124 0.0182
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0016 0.0017
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0082 0.0062
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0066 0.0579 0.0953
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0082 0.0105
Echinococcus multilocularis heat shock protein 0.0025 0.0148 0.0128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0079 0.0036
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0082 0.0062
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0082 0.0041
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0059 0.0497 0.0815
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0061 0.0041
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0061 0.0038
Onchocerca volvulus 0.0023 0.0124 0.0206
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0114 0.0095
Trypanosoma cruzi peter pan protein, putative 0.0061 0.052 0.0879
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0082 0.0041
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0118 0.0098
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0079 0.006
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0082 0.0111
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0079 0.011
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0023 0.0124 0.0182
Onchocerca volvulus 0.0019 0.0082 0.0123
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.03 0.0477
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0041
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0082 0.0111
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0079 0.0036
Brugia malayi thymidylate synthase 0.0123 0.1174 0.1965
Toxoplasma gondii heat shock protein HSP90 0.0025 0.0148 0.0188
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0118 0.0134
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.002 0.0033
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0082 0.0062
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0082 0.0041
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0124 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0023 0.0124 0.0147
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0061 0.0077
Trichomonas vaginalis rotamase, putative 0.0035 0.0248 0.0408
Giardia lamblia Grp94/Hsp90 0.0029 0.0187 0.2428
Echinococcus granulosus p2X purinoceptor 4 0.0334 0.3391 0.5715
Echinococcus granulosus allatostatin A receptor 0.0019 0.0082 0.0105
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0082 0.0115
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0082 0.0105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.1238 0.2084
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0129 0.1238 0.2066
Trypanosoma brucei trypanothione reductase 0.0049 0.0399 0.0665
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0978
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0098 0.0165
Schistosoma mansoni rab6-interacting 0.0022 0.0118 0.0102
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0082 0.0062
Schistosoma mansoni lamin 0.006 0.0512 0.0775
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0248 0.0389
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.037 0.0594
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0075 0.0672 0.1047
Echinococcus granulosus 6 phosphofructokinase 0.0129 0.1238 0.2066
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0248 0.194
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0079 0.01
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0023 0.0124 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0082 0.0105
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Brugia malayi ORL1-like opioid receptor 0.0019 0.0082 0.0115
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0082 0.0062
Loa Loa (eye worm) hypothetical protein 0.0022 0.0118 0.0173
Brugia malayi Serotonin receptor 0.0019 0.0082 0.0115
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.03 0.0408
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0079 0.01
Echinococcus multilocularis endoplasmin 0.0029 0.0187 0.0168
Brugia malayi AKH receptor 0.0019 0.0082 0.0115
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus granulosus transcription factor Dp 1 0.0044 0.0339 0.0541
Echinococcus granulosus single minded 2 0.0037 0.0274 0.0431
Echinococcus granulosus bloom syndrome protein 0.0022 0.0114 0.0161
Schistosoma mansoni adenosylhomocysteinase 0.0356 0.3618 0.6074
Schistosoma mansoni ap endonuclease 0.004 0.03 0.0413
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0021 0.0098 0.0165
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0124 0.0209
Echinococcus granulosus somatostatin receptor 0.0019 0.0082 0.0105
Entamoeba histolytica acyl-coA synthetase, putative 0.0078 0.0705 0.1182
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0079 0.011
Echinococcus multilocularis expressed protein 0.0365 0.3716 0.3703
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0098 0.0165
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0082 0.0111
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0079 0.0036
Brugia malayi hypothetical protein 0.0022 0.0118 0.0176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Brugia malayi G-protein coupled receptor 0.0019 0.0082 0.0115
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0082 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Plasmodium falciparum glutathione reductase 0.0017 0.0061 0.0072
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.03 0.0481
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0148 0.025
Schistosoma mansoni loxhd1 0.0022 0.0118 0.0102
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0017 0.0058 0.0038
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0248 0.041
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0082 0.0105
Entamoeba histolytica acyl-CoA synthetase, putative 0.0078 0.0705 0.1182
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.03 0.1919
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0079 0.01
Schistosoma mansoni amine GPCR 0.0019 0.0082 0.0041
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.002 0.0023
Trypanosoma cruzi Heat shock protein 83, putative 0.0025 0.0148 0.025
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0239 0.0394
Brugia malayi Adenosylhomocysteinase 0.0575 0.5919 1
Schistosoma mansoni neuropeptide receptor 0.0019 0.0082 0.0041
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0079 0.0107
Echinococcus granulosus RUN 0.0022 0.0118 0.0166
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0043 0.0338 0.0562
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0107
Echinococcus multilocularis serotonin receptor 0.0019 0.0082 0.0062
Chlamydia trachomatis dihydrofolate reductase 0.0125 0.1199 1
Leishmania major S-adenosylhomocysteine hydrolase 0.0575 0.5919 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0082 0.0041
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0082 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus granulosus serotonin receptor 0.0019 0.0082 0.0105
Loa Loa (eye worm) phosphofructokinase 0.0129 0.1238 0.2071
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0082 0.0111
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0082 0.0115
Echinococcus granulosus intermediate filament protein 0.006 0.0512 0.0835
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0124 0.0182
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.1062 0.1709
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0079 0.0123
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.1062 0.1709
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0082 0.0062
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0079 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0082 0.0111
Echinococcus granulosus heat shock protein 0.0025 0.0148 0.0217
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0079 0.011
Plasmodium vivax heat shock protein 90, putative 0.0017 0.0058 0.0032
Loa Loa (eye worm) endoplasmin 0.0025 0.0148 0.0223
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus multilocularis zinc finger protein 598 0.006 0.0516 0.0497
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0079 0.0036
Echinococcus multilocularis dihydrofolate reductase 0.0125 0.1199 0.1182
Schistosoma mansoni hypothetical protein 0.0022 0.0118 0.0102
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0575 0.5919 1
Trichomonas vaginalis conserved hypothetical protein 0.031 0.3134 0.5291
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0061 0.0038
Plasmodium vivax acyl-CoA synthetase, putative 0.0059 0.0497 0.0779
Onchocerca volvulus 0.0019 0.0082 0.0123
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0079 0.0123
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Schistosoma mansoni heat shock protein 0.0025 0.0148 0.0154
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0079 0.0059
Mycobacterium ulcerans hypothetical protein 0.0078 0.0705 0.1167
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0082 0.0115
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0579 0.0889
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.002 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Brugia malayi Cytochrome P450 family protein 0.0013 0.0016 0.0004
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0534 0.0515
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0082 0.0105
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0248 0.2491 0.419
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0534 0.0812
Brugia malayi G-protein coupled receptor 0.0019 0.0082 0.0115
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0082 0.0111
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0082 0.0062
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0017 0.0058 0.0087
Schistosoma mansoni opsin-like receptor 0.0019 0.0082 0.0041
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0061 0.0077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0148 0.024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0463 0.0686
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0148 0.025
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0079 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.0124 0.0186
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0017 0.0058 0.0076
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Loa Loa (eye worm) hypothetical protein 0.0029 0.0186 0.0288
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0079 0.0107
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0575 0.5919 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0248 0.194
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0118 0.0168
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.1062 0.1709
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0082 0.0105
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.037 0.0615
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0079 0.0036
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0079 0.01
Mycobacterium tuberculosis Conserved hypothetical protein 0.012 0.1141 0.1843
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0124 0.0186
Leishmania major peter pan protein, putative 0.0061 0.052 0.0879
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0082 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0705 0.1171
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0579 0.0889
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0006 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0575 0.5919 1
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0082 0.0062
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0065 0.0013
Schistosoma mansoni opsin-like receptor 0.0019 0.0082 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0124 0.0186
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0534 0.0844
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0129 0.1238 0.9457
Giardia lamblia Peter pan protein 0.0061 0.052 0.8864
Treponema pallidum heat shock protein 90 0.0029 0.0187 0.1009
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0082 0.0105
Loa Loa (eye worm) hypothetical protein 0.0043 0.0338 0.0546
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0079 0.0134
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0148 0.025
Trichomonas vaginalis endoplasmin, putative 0.0013 0.0019 0.0021
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.002 0.0023
Schistosoma mansoni lipoxygenase 0.0134 0.1293 0.2107
Onchocerca volvulus 0.0019 0.0082 0.0123
Schistosoma mansoni rotamase 0.0035 0.0248 0.0324
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0061 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.022 0.0345
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1238 0.2084
Trypanosoma cruzi peter pan protein, putative 0.0061 0.052 0.0879
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0061 0.0071
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0248 0.0356
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0248 0.041
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0043 0.0338 0.0571
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0023 0.0124 0.0106
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0023 0.0124 0.0106
Echinococcus multilocularis adenosylhomocysteinase 0.0575 0.5919 0.5911
Onchocerca volvulus 0.006 0.0512 0.0978
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0046 0.0363 0.0588
Toxoplasma gondii 5'-nucleotidase, C-terminal domain-containing protein 0.0136 0.1306 0.2157
Echinococcus granulosus thymidylate synthase 0.0123 0.1174 0.1957
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0006 0.001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.1194 0.1934
Giardia lamblia Hypothetical protein 0.0055 0.0464 0.7784
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0082 0.0111
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.1238 0.2014
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0125 0.1199 0.1942
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0082 0.0115
Entamoeba histolytica heat shock protein 90, putative 0.0025 0.0148 0.024
Loa Loa (eye worm) glutathione reductase 0.0049 0.0399 0.065
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0575 0.5919 1
Echinococcus granulosus g protein coupled receptor 0.0019 0.0082 0.0105
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0079 0.0059
Schistosoma mansoni adenoreceptor 0.0019 0.0082 0.0041
Trichomonas vaginalis ap endonuclease, putative 0.004 0.03 0.0497
Brugia malayi Endoplasmin precursor 0.0025 0.0148 0.0227
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0672 0.1049
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0124 0.0186
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0148 0.024
Brugia malayi hypothetical protein 0.0022 0.0118 0.0176
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0187 0.0306
Echinococcus multilocularis tar DNA binding protein 0.0075 0.0672 0.0654
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.1194 0.1934
Brugia malayi neuropeptide F receptor 0.0019 0.0082 0.0115
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0302 0.3057 0.3043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Onchocerca volvulus 0.0019 0.0082 0.0123
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0082 0.0062
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.1238 0.2092
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0274 0.0441
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0082 0.0105
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0124 0.0106
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0672 0.1049
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0414 0.069
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0399 0.0644
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0248 0.041
Brugia malayi Dopamine receptor protein 2 0.0019 0.0082 0.0115
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0043 0.0338 0.0571
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0079 0.0059
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0705 0.1191
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.03 0.0281
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0579 0.0978
Brugia malayi hypothetical protein 0.0019 0.0079 0.011
Loa Loa (eye worm) hypoxia-induced factor 1 0.0156 0.1521 0.2551
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus multilocularis sex peptide receptor 0.0019 0.0082 0.0062
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0043 0.0338 0.0561
Echinococcus multilocularis lamin dm0 0.006 0.0512 0.0493
Echinococcus multilocularis p2X purinoceptor 4 0.0334 0.3391 0.3378
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0082 0.0105
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0075 0.0672 0.1112
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0082 0.0041
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0082 0.0111
Onchocerca volvulus 0.0022 0.0118 0.0195
Trichomonas vaginalis set domain proteins, putative 0.0492 0.5053 0.8537
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0023 0.0124 0.0176
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0023 0.0122 0.0184
Brugia malayi dihydrofolate reductase family protein 0.0125 0.1199 0.2007
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0079 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0082 0.0105
Echinococcus granulosus sex peptide receptor 0.0019 0.0082 0.0105
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0066 0.0579 0.0921
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0082 0.0062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0082 0.0041
Schistosoma mansoni rab6-interacting 0.0022 0.0118 0.0102
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0023 0.0124 0.0147
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0082 0.0105
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0248 0.2491 0.4208
Mycobacterium ulcerans thymidylate synthase 0.0123 0.1174 0.1962
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0079 0.0071
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0023 0.0124 0.0178
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Toxoplasma gondii thioredoxin reductase 0.0049 0.0399 0.0616
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0412 0.0604
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0148 0.0217
Brugia malayi TAR-binding protein 0.0075 0.0672 0.1116
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0079 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0705 0.1099
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0082 0.0062
Brugia malayi Brix domain containing protein 0.0061 0.052 0.0857
Brugia malayi isocitrate dehydrogenase 0.0019 0.0079 0.0111
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0082 0.0062
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0082 0.0041
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.002 0.0006
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0082 0.0062
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0023 0.0124 0.0199
Brugia malayi Cytochrome P450 family protein 0.0013 0.0016 0.0004
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Brugia malayi hypothetical protein 0.0059 0.0497 0.0818
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0248 0.0392
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0082 0.0041
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0118 0.0098
Echinococcus multilocularis somatostatin receptor 0.0019 0.0082 0.0062
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0061 0.0006
Onchocerca volvulus 0.0023 0.0124 0.0206
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0061 0.0072
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0082 0.0041
Onchocerca volvulus 0.0019 0.0082 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trichomonas vaginalis ssf, putative 0.0061 0.052 0.0869
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0248 0.0408
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0186 0.0282
Brugia malayi larval opioid receptor 0.0019 0.0082 0.0115
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0023 0.0124 0.0182
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0187 0.0306
Schistosoma mansoni amine GPCR 0.0019 0.0082 0.0041
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.03 0.4615
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0302 0.3057 0.5149
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0082 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0534 0.0812
Mycobacterium tuberculosis Hypothetical protein 0.0059 0.0497 0.0743
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0023 0.0124 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0082 0.0062
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0061 0.0093
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0082 0.0062
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0066 0.0579 0.0968
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0082 0.0105
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0082 0.0041
Loa Loa (eye worm) hypothetical protein 0.0051 0.0421 0.0685
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0497 0.0829
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0082 0.0105
Loa Loa (eye worm) hypothetical protein 0.0059 0.0497 0.0815
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0066 0.0579 0.4157
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.0338 0.0546
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0066 0.0579 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Loa Loa (eye worm) intermediate filament protein 0.006 0.0512 0.0841
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0114 0.017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0043 0.0338 0.0571
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.037 0.5957
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0023 0.0124 0.0106
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0079 0.0071
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0079 0.01
Schistosoma mansoni 23-cyclic-nucleotide 2-phosphodiesterase 0.0135 0.1302 0.2123
Onchocerca volvulus 0.0019 0.0082 0.0123
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0082 0.0105
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0023 0.0124 0.0209
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0705 0.1167
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.1238 0.2071
Plasmodium falciparum adenosylhomocysteinase 0.0575 0.5919 1
Schistosoma mansoni intermediate filament proteins 0.006 0.0512 0.0775
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0066 0.0579 0.0889
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Brugia malayi Thioredoxin reductase 0.0049 0.0399 0.0653
Schistosoma mansoni tar DNA-binding protein 0.0075 0.0672 0.1049
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.002 0.0023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.03 0.0507
Schistosoma mansoni P2X receptor subunit 0.0334 0.3391 0.5687
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0148 0.025
Mycobacterium tuberculosis Probable reductase 0.0112 0.1062 0.1709
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0075 0.0672 0.1114
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0082 0.0062
Trypanosoma brucei Heat shock protein 83, putative 0.0025 0.0148 0.024
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0079 0.0123
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0079 0.0107
Brugia malayi 6-phosphofructokinase 0.0129 0.1238 0.2074
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0029 0.0187 0.0284
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0082 0.0105
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.1194 0.1991
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0079 0.0036
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Onchocerca volvulus 0.0078 0.0705 0.1361
Leishmania major heat shock protein, putative 0.0017 0.0058 0.0098
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0079 0.006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0023 0.0124 0.0182
Onchocerca volvulus 0.0019 0.0082 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0107
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0082 0.0041
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0059 0.0497 0.4047
Echinococcus multilocularis RUN 0.0022 0.0118 0.0098
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Trypanosoma brucei heat shock protein 90, putative 0.0025 0.0148 0.024
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.1062 0.1709
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0082 0.0062
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0079 0.0059
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0086 0.0114
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0061 0.0093
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0082 0.0105
Brugia malayi G protein-coupled receptor 0.0019 0.0082 0.0115
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0079 0.0134
Brugia malayi neuropeptide F receptor 0.0019 0.0082 0.0115
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0124 0.0176
Trypanosoma cruzi heat shock protein 90, putative 0.0012 0.0011 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0079 0.0123
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0041
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0079 0.01
Trypanosoma cruzi heat shock protein, putative 0.0017 0.0058 0.0098
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.051 0.0831
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0118 0.0166
Loa Loa (eye worm) adenosylhomocysteinase 0.0575 0.5919 1
Trichomonas vaginalis hypothetical protein 0.0069 0.0608 0.1018
Schistosoma mansoni adenosylhomocysteinase 0.0356 0.3618 0.6074
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0075 0.0672 0.1125
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0082 0.0062
Brugia malayi RNA recognition motif domain containing protein 0.0075 0.0672 0.1116
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0124 0.0199
Brugia malayi hypothetical protein 0.0169 0.1659 0.2787
Brugia malayi RNA binding protein 0.0075 0.0672 0.1116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0118 0.0166
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0078 0.0705 0.1167
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0705 0.1167
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0415 0.0691
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.03 0.0497
Echinococcus granulosus neuropeptide receptor 0.0019 0.0082 0.0105
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0079 0.0059
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0248 0.1503
Toxoplasma gondii propionate-CoA ligase 0.0023 0.0124 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0082 0.0062
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0239 0.0394
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0123 0.1174 0.1904
Toxoplasma gondii Hsp90 domain-containing protein 0.0017 0.0058 0.0035
Schistosoma mansoni biogenic amine receptor 0.0019 0.0082 0.0041
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0082 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0079 0.01
Schistosoma mansoni opsin-like receptor 0.0019 0.0082 0.0041
Schistosoma mansoni myosin xvIII 0.0019 0.0082 0.0041
Brugia malayi PAS domain containing protein 0.005 0.0412 0.0674
Loa Loa (eye worm) hypothetical protein 0.0023 0.0124 0.0182
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0107
Mycobacterium ulcerans ketopantoate reductase, ApbA 0.031 0.3134 0.5283
Schistosoma mansoni endoplasmin 0.0025 0.0148 0.0154
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0248 0.0396
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0061 0.0077
Plasmodium vivax heat shock protein 86, putative 0.0025 0.0148 0.0185
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0079 0.0111
Loa Loa (eye worm) hypothetical protein 0.0078 0.0705 0.1167
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0124 0.0209
Schistosoma mansoni P2X receptor subunit 0.0199 0.1973 0.3268
Onchocerca volvulus 0.0019 0.0082 0.0123
Brugia malayi Dopamine receptor protein 1 0.0019 0.0082 0.0115
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0705 0.1191
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0107
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0082 0.0105
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0079 0.006
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0705 0.1171
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0082 0.0062
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0079 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0079 0.0123
Plasmodium vivax SET domain protein, putative 0.0062 0.0534 0.0841
Schistosoma mansoni hypothetical protein 0.0019 0.0082 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.03 0.0497
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0172 0.169 0.2786
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0705 0.1162
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0239 0.0404
Loa Loa (eye worm) acetyltransferase 0.0172 0.169 0.2837
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0579 0.0968
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0968
Echinococcus granulosus fmrfamide receptor 0.0019 0.0082 0.0105
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0082 0.0115
Onchocerca volvulus 0.0023 0.0124 0.0206
Echinococcus multilocularis expressed protein 0.0035 0.0248 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0079 0.0036
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0579 0.0978
Plasmodium falciparum heat shock protein 90 0.0025 0.0148 0.0219
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0075 0.0672 0.1135
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0023 0.0124 0.0182
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0978
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0107
Loa Loa (eye worm) hypothetical protein 0.0059 0.0497 0.0815
Brugia malayi heat shock protein 90 0.0025 0.0148 0.0227
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0079 0.011
Onchocerca volvulus 0.0019 0.0082 0.0123
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0082 0.0105
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0082 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Mycobacterium ulcerans acetyl-CoA synthetase 0.0023 0.0124 0.0182
Brugia malayi Pre-SET motif family protein 0.0433 0.4426 0.7472
Plasmodium falciparum glutathione reductase 0.0049 0.0399 0.0645
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0414 0.0668
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0082 0.0041
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus multilocularis heat shock protein 90 0.0025 0.0148 0.0128
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0248 0.0359
Entamoeba histolytica hypothetical protein 0.0019 0.0079 0.0123
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0082 0.0041
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0023 0.0124 0.0209
Trichomonas vaginalis antibiotic synthetase, putative 0.0023 0.0124 0.0199
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0082 0.0062
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0421 0.0619
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0082 0.0105
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0672 0.1135
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0414 0.064
Schistosoma mansoni peter pan-related 0.0061 0.052 0.0788
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0017 0.0058 0.0065
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.03 0.0481
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0082 0.0062
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.009 0.0049
Trypanosoma brucei heat shock protein 90, putative 0.0025 0.0148 0.024
Schistosoma mansoni lipoxygenase 0.0094 0.0868 0.1383
Schistosoma mansoni peter pan-related 0.0061 0.052 0.0788
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0123 0.1174 0.1899
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Loa Loa (eye worm) RecQ helicase 0.0022 0.0114 0.0167
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0302 0.3057 0.5117
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Mycobacterium ulcerans 2-dehydropantoate 2-reductase 0.012 0.1141 0.1905
Loa Loa (eye worm) RNA binding protein 0.0075 0.0672 0.1112
Onchocerca volvulus 0.0037 0.0274 0.0505
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0248 0.041
Loa Loa (eye worm) hypothetical protein 0.006 0.0512 0.0841
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0043 0.0338 0.0546
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus multilocularis thymidylate synthase 0.0123 0.1174 0.1156
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.03 0.0507
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0066 0.0579 0.0978
Onchocerca volvulus 0.0019 0.0082 0.0123
Schistosoma mansoni dihydrofolate reductase 0.0125 0.1199 0.1947
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.002 0.0033
Onchocerca volvulus 0.0492 0.5053 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0079 0.0107
Leishmania major heat shock protein 83-1 0.0025 0.0148 0.025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0082 0.0105
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0399 0.0577
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0066 0.0579 0.0968
Echinococcus granulosus g protein coupled receptor 0.0019 0.0082 0.0105
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0021 0.0098 0.0142
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0098 0.0165
Onchocerca volvulus 0.006 0.0512 0.0978
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0248 0.041
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0124 0.0182
Schistosoma mansoni ap endonuclease 0.004 0.03 0.0413
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0023 0.0124 0.0106
Schistosoma mansoni biogenic amine receptor 0.0019 0.0082 0.0041
Echinococcus multilocularis tumor protein p63 0.035 0.3561 0.3549
Trypanosoma brucei heat shock protein, putative 0.0025 0.0148 0.024
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0079 0.0036
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0134 0.1293 0.1275
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0066 0.0579 1
Schistosoma mansoni histamine h1 receptor 0.0019 0.0082 0.0041
Onchocerca volvulus 0.0123 0.1174 0.2293
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0078 0.0705 0.1167
Echinococcus granulosus expressed protein 0.0365 0.3716 0.6266
Echinococcus granulosus adenosylhomocysteinase 0.0575 0.5919 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0061 0.0104
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0066 0.0579 0.4741
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1238 0.2084
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0414 0.0637
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0023 0.0124 0.0104
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0082 0.0111
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0172 0.169 0.1674
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0248 0.3616
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0061 0.0093
Leishmania major trypanothione reductase 0.0049 0.0399 0.0675
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0512 0.0841
Loa Loa (eye worm) dihydrofolate reductase 0.0125 0.1199 0.2004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Echinococcus granulosus dihydrofolate reductase 0.0125 0.1199 0.1999
Loa Loa (eye worm) hypothetical protein 0.0013 0.002 0.0006
Schistosoma mansoni acetyl-CoA synthetase 0.0023 0.0124 0.0112
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0023 0.0124 0.0209
Brugia malayi 6-phosphofructokinase 0.0129 0.1238 0.2074
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0125 0.1199 0.1999
Brugia malayi Pre-SET motif family protein 0.0062 0.0534 0.0881
Loa Loa (eye worm) hypothetical protein 0.0028 0.0175 0.0269
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0512 0.0844
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0248 0.2491 0.4202
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0082 0.0041
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.1238 0.2071
Treponema pallidum 5'-nucleotidase (ushA) 0.0136 0.1306 1
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0043 0.0338 0.0319
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0066 0.0579 0.0948
Schistosoma mansoni biogenic amine receptor 0.0019 0.0082 0.0041
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0248 0.0359
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0079 0.0134
Brugia malayi hypothetical protein 0.0019 0.0082 0.0115
Onchocerca volvulus 0.0019 0.0082 0.0123
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0082 0.0105
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0705 0.1171
Loa Loa (eye worm) hypothetical protein 0.0078 0.0705 0.1167
Entamoeba histolytica hypothetical protein 0.0019 0.0079 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.002 0.0023
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0079 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0079 0.0036
Brugia malayi Dopamine receptor 0.0019 0.0082 0.0115
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0079 0.0036
Brugia malayi putative neuropeptide receptor 0.0019 0.0082 0.0115
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0082 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0079 0.0123
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.03 0.0444
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0023 0.0124 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0082 0.0041
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0124 0.0182
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0023 0.0123 0.0105
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.1194 0.1934
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.002 0.0023
Echinococcus granulosus p2X purinoceptor 4 0.0334 0.3391 0.5715
Loa Loa (eye worm) hypothetical protein 0.0078 0.0705 0.1167
Echinococcus granulosus orexin receptor type 2 0.0019 0.0082 0.0105
Echinococcus granulosus histone acetyltransferase KAT2B 0.0167 0.164 0.2746
Echinococcus granulosus heat shock protein 90 0.0025 0.0148 0.0217
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.03 0.0507
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0124 0.0106
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0079 0.0059

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 280 nM Displacement of [125I]-NDP-MSH from human MC4R expressed in HEK293 cells ChEMBL. 18082401
Ki (binding) = 280 nM Displacement of [125I]-NDP-MSH from human MC4R expressed in HEK293 cells ChEMBL. 18082401

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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