Detailed information for compound 619578

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 278.39 | Formula: C15H20NO2S
  • H donors: 0 H acceptors: 1 LogP: 3.66 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1cccc2c1[C](=NC(=O)C(C)(C)C)(S2)C
  • InChi: 1S/C15H20N2O2S/c1-6-19-10-8-7-9-11-12(10)17(5)14(20-11)16-13(18)15(2,3)4/h7-9H,6H2,1-5H3/b16-14+
  • InChiKey: DWPICRTZFDFVSK-JQIJEIRASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0071 0.0731
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0004 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0069 0.0159
Leishmania major glycerol uptake protein, putative 0.0021 0.0069 0.0158
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0071 0.0125
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0021 0.0069 0.0158
Echinococcus multilocularis serine:threonine protein kinase N2 0.004 0.0159 0.0299
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0004 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0033 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0012 0.002
Plasmodium falciparum ornithine aminotransferase 0.0071 0.0302 1
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0499 0.2285 0.5437
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0021 0.0069 0.0156
Entamoeba histolytica vacuolar protein sorting 26 0.0021 0.0069 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Brugia malayi beta-lactamase family protein 0.0076 0.0326 0.0645
Trypanosoma brucei glycerol uptake protein, putative 0.0021 0.0069 0.0706
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0326 0.0783
Leishmania major glycerol uptake protein, putative 0.0021 0.0069 0.0158
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0021 0.0069 0.1363
Onchocerca volvulus 0.0076 0.0326 0.1927
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0071 0.0302 0.0298
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0071 0.0731
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0326 0.0339
Mycobacterium leprae Probable lipase LipE 0.0076 0.0326 0.059
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0069 0.0159
Entamoeba histolytica G protein alpha subunit, putative 0.0008 0.001 0.0013
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0326 0.3347
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0044 0.0071
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0058 0.0241 0.7952
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.001 0.0009
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0049 0.0202 0.0395
Loa Loa (eye worm) hypothetical protein 0.0049 0.0202 0.0395
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0071 0.072
Echinococcus granulosus protein kinase c epsilon type 0.0044 0.0176 0.0334
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0071 0.0017
Brugia malayi hypothetical protein 0.0008 0.001 0.0012
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0152 0.0286
Loa Loa (eye worm) hypothetical protein 0.0076 0.0326 0.0645
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0071 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0326 0.3339
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0072 0.2282
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0071 0.0302 0.6227
Entamoeba histolytica hypothetical protein 0.0023 0.0082 0.0187
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0326 0.0325
Schistosoma mansoni GTP-binding protein alpha subunit 0.0008 0.001 0.0015
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0008 0.001 0.0015
Onchocerca volvulus 0.0031 0.0118 0.0656
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0088 0.1235
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0021 0.0069 0.0158
Loa Loa (eye worm) hypothetical protein 0.1087 0.5013 1
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0152 0.0286
Toxoplasma gondii exonuclease III APE 0.0018 0.0058 0.1138
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0058 0.0098
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.0856 0.394 0.4904
Schistosoma mansoni carbonic anhydrase 0.0049 0.0202 0.048
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0012
Schistosoma mansoni cpg binding protein 0.0061 0.0254 0.0608
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0012 0.0006
Schistosoma mansoni hypothetical protein 0.0308 0.1402 0.339
Loa Loa (eye worm) MBOAT family protein 0.0021 0.0069 0.013
Onchocerca volvulus 0.0057 0.0239 0.1397
Loa Loa (eye worm) inositol-1 0.0039 0.0152 0.0297
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0021 0.0069 0.0701
Schistosoma mansoni inositol monophosphatase 0.0039 0.0152 0.0361
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0184 0.0826 0.1633
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0058 0.0241 0.0237
Schistosoma mansoni Smad4 0.0008 0.0012 0.002
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0021 0.0069 0.013
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0499 0.2285 0.2282
Entamoeba histolytica PH domain containing protein kinase, putative 0.0036 0.0139 0.0326
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.072
Loa Loa (eye worm) hhat protein 0.0021 0.0069 0.013
Plasmodium vivax ornithine aminotransferase, putative 0.0071 0.0302 0.9235
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0058 0.0595
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0134 0.0095
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0184 0.0826 0.1633
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0021 0.0069 0.012
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0216 0.0976 1
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0071 0.0135
Onchocerca volvulus 0.0238 0.1079 0.6508
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0216 0.0976 0.194
Mycobacterium leprae Probable transmembrane transport protein 0.0418 0.1913 0.4518
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0021 0.0069 0.012
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0107 0.0195
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0088 0.2619
Loa Loa (eye worm) hhat protein 0.0021 0.0069 0.013
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0326 0.0645
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0064 0.011
Brugia malayi MBOAT family protein 0.0021 0.0069 0.013
Entamoeba histolytica Ran family GTPase 0.0021 0.0072 0.0163
Loa Loa (eye worm) hypothetical protein 0.0049 0.0202 0.0395
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0033 0.0032
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0061 0.0103
Leishmania major DNA polymerase eta, putative 0.0021 0.0071 0.0164
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0152 0.0151
Onchocerca volvulus 0.0051 0.021 0.1221
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0326 0.0635
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0033 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0033 0.0032
Echinococcus multilocularis smad 0.0008 0.0012 0.0006
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0008 0.001 0.0002
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0021 0.0069 0.0158
Echinococcus granulosus o acyltransferase membrane bound domain 0.0021 0.0069 0.012
Plasmodium falciparum carbonic anhydrase 0.0049 0.0202 0.6643
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0072 0.0125
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0418 0.1913 0.2344
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0118 0.0276
Entamoeba histolytica hypothetical protein 0.0021 0.0069 0.0156
Trypanosoma cruzi DNA damage repair protein, putative 0.0007 0.0004 0.0026
Trichomonas vaginalis transmembrane protein nessy, putative 0.0021 0.0069 0.0068
Echinococcus granulosus dna polymerase kappa 0.0021 0.0071 0.0125
Trypanosoma brucei unspecified product 0.0021 0.0071 0.0731
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0008 0.001 0.0012
Leishmania major DNA polymerase kappa, putative 0.0021 0.0071 0.0164
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0118 0.0276
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0061 0.0103
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0021 0.0069 0.0701
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Treponema pallidum alginate O-acetylation protein (algI) 0.0021 0.0069 0.3582
Toxoplasma gondii AGC kinase 0.0021 0.0069 0.1374
Echinococcus multilocularis cpg binding protein 0.0061 0.0254 0.0491
Schistosoma mansoni loxhd1 0.002 0.0064 0.0146
Loa Loa (eye worm) hypothetical protein 0.0031 0.0118 0.0228
Toxoplasma gondii histone lysine methyltransferase SET1 0.011 0.0482 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.0131
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0216 0.0976 1
Echinococcus granulosus dnaJ subfamily B 0.041 0.1873 0.3724
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0021 0.0069 0.012
Plasmodium falciparum importin beta, putative 0.0029 0.0107 0.3467
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0152 0.1552
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0176 0.0418
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0027 0.0037
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0088 0.0904
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Mycobacterium ulcerans acetylornithine aminotransferase 0.0071 0.0302 0.0298
Onchocerca volvulus 0.0076 0.0326 0.1927
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0326 0.0325
Brugia malayi beta-lactamase 0.0076 0.0326 0.0645
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0008 0.001 0.0012
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0021 0.0069 0.012
Trichomonas vaginalis conserved hypothetical protein 0.2163 1 1
Brugia malayi MH2 domain containing protein 0.0123 0.0542 0.1074
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0021 0.0069 0.1374
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.0826 0.1995
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.001 0.0015
Trypanosoma cruzi glycerol uptake protein, putative 0.0021 0.0069 0.0695
Mycobacterium tuberculosis Conserved protein 0.0076 0.0326 0.0339
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0326 0.0325
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0107 0.0196
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0012 0.002
Echinococcus granulosus o acyltransferase membrane bound domain 0.0021 0.0069 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0033 0.0032
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0152 0.0151
Leishmania major hypothetical protein, conserved 0.0026 0.0094 0.0219
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0058 0.0054
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0058 0.1687
Leishmania major importin beta-1 subunit, putative 0.0023 0.0082 0.0189
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0008 0.001 0.0012
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0072 0.0136
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0326 0.0645
Loa Loa (eye worm) hypothetical protein 0.0076 0.0326 0.0645
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0069 0.0159
Loa Loa (eye worm) beta-lactamase 0.0076 0.0326 0.0645
Loa Loa (eye worm) hypothetical protein 0.0076 0.0326 0.0645
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0382 0.0918
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.001 0.0009
Echinococcus granulosus carbonic anhydrase 0.0049 0.0202 0.0385
Plasmodium vivax sulfate transporter, putative 0.0058 0.0241 0.7344
Trichomonas vaginalis helicase, putative 0.0013 0.0033 0.0032
Leishmania major glycerol uptake protein, putative 0.0021 0.0069 0.0158
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0088 0.1766
Echinococcus granulosus expressed protein 0.0008 0.001 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.0007 0.0004 0.0026
Trichomonas vaginalis esterase, putative 0.0076 0.0326 0.0325
Plasmodium vivax SET domain protein, putative 0.0031 0.0118 0.353
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0118 0.2381
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0072 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0072 0.2107
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0071 0.0302 0.0529
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.002 0.0068 0.0118
Schistosoma mansoni DNA polymerase eta 0.0021 0.0071 0.0164
Echinococcus multilocularis Aminotransferase class III 0.0071 0.0302 0.0585
Echinococcus multilocularis Smad4 0.0008 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.013
Trypanosoma cruzi GUP1, putative 0.0021 0.0069 0.0695
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0071 0.0302 0.0308
Leishmania major glycerol uptake protein, putative 0.0021 0.0069 0.0158
Loa Loa (eye worm) hypothetical protein 0.0076 0.0326 0.0645
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0071 0.0302 1
Entamoeba histolytica hypothetical protein 0.0025 0.0088 0.0203
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.006 0.0112
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0016 0.0031
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0094 0.0952
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.1136 0.2253
Toxoplasma gondii hypothetical protein 0.0021 0.0069 0.1363
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0021 0.0069 0.0121
Toxoplasma gondii ABC1 family protein 0.0076 0.0326 0.6743
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0326 0.3339
Trichomonas vaginalis hypothetical protein 0.0007 0.0006 0.0004
Schistosoma mansoni importin beta-1 0.0029 0.0107 0.0251
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0088 0.2836
Brugia malayi follicle stimulating hormone receptor 0.0736 0.3387 0.6755
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0945 0.188
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0072 0.1421
Echinococcus granulosus carbonic anhydrase 0.0049 0.0202 0.0385
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0044 0.0071
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0152 0.1552
Echinococcus multilocularis carbonic anhydrase II 0.0216 0.0976 0.1932
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0021 0.0069 0.1363
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0041 0.0419
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0021 0.0069 0.2021
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0021 0.0069 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0041 0.0419
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0033 0.0032
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.002
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0008 0.001 0.0015
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0021 0.0069 0.0121
Schistosoma mansoni zinc finger protein 0.024 0.1084 0.2619
Mycobacterium ulcerans hypothetical protein 0.0076 0.0326 0.0323
Schistosoma mansoni GTP-binding protein alpha subunit 0.0008 0.001 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.072
Loa Loa (eye worm) hypothetical protein 0.0076 0.0326 0.0645
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0184 0.0826 0.1633
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0071 0.0125
Loa Loa (eye worm) hypothetical protein 0.0088 0.0382 0.0756
Echinococcus granulosus dna polymerase eta 0.0021 0.0071 0.0125
Giardia lamblia DINP protein human, muc B family 0.0021 0.0071 0.9947
Trypanosoma cruzi DNA damage repair protein, putative 0.0007 0.0004 0.0026
Echinococcus granulosus snurportin 1 0.0308 0.1402 0.2784
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0107 0.2159
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0012 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0069 0.0068
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0021 0.0069 0.012
Schistosoma mansoni hypothetical protein 0.0021 0.0069 0.0158
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0382 0.0746
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0027 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0021 0.0069 0.012
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0326 0.0339
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0071 0.0302 1
Echinococcus multilocularis ornithine aminotransferase 0.0071 0.0302 0.0585
Loa Loa (eye worm) hypothetical protein 0.0076 0.0326 0.0645
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0049 0.0202 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0088 0.0038
Schistosoma mansoni carbonic anhydrase 0.0896 0.4128 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0118 0.0276
Leishmania major glycerol uptake protein, putative 0.0021 0.0069 0.0158
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0021 0.0069 0.2189
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0021 0.0069 0.0121
Schistosoma mansoni cpg binding protein 0.0061 0.0254 0.0608
Mycobacterium tuberculosis Conserved protein 0.0076 0.0326 0.0339
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0094 0.1885
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.024 0.1084 0.2148
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0094 0.3027
Schistosoma mansoni polycystin 1-related 0.002 0.0064 0.0146
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0094 0.0962
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0058 0.0241 0.0237
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0058 0.0109
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0008 0.001 0.0002
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0021 0.0069 0.0121
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0006 0.0004
Echinococcus granulosus carbonic anhydrase 0.0049 0.0202 0.0385
Leishmania major GTP-binding protein, putative 0.0021 0.0072 0.0165
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0008 0.001 0.0002
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0058 0.0241 0.2459
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0071 0.0302 0.0308
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0021 0.0069 0.0711
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0071 0.0302 0.0298
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0071 0.0135
Schistosoma mansoni smad 0.0008 0.0012 0.002
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0021 0.0069 0.0158
Brugia malayi MH2 domain containing protein 0.0008 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0012
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0184 0.0826 0.1642
Onchocerca volvulus 0.0021 0.0069 0.036
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0008 0.001 0.0015
Loa Loa (eye worm) MBOAT family protein 0.024 0.1084 0.2156
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0008 0.001 0.0015
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0058 0.0098
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0071 0.0302 0.0308
Echinococcus granulosus muscleblind protein 0.1087 0.5013 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0071 0.0164
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0326 0.0783
Schistosoma mansoni inositol monophosphatase 0.0039 0.0152 0.0361
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0216 0.0976 0.194
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0058 0.0241 0.2467
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.1725 0.7973 1
Echinococcus granulosus Aminotransferase class III 0.0071 0.0302 0.0585
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0152 0.1561
Onchocerca volvulus 0.002 0.0064 0.0329
Brugia malayi hypothetical protein 0.002 0.0064 0.012
Echinococcus multilocularis protein kinase c epsilon type 0.0044 0.0176 0.0334
Brugia malayi Pre-SET motif family protein 0.021 0.0945 0.188
Brugia malayi MBOAT family protein 0.0021 0.0069 0.013
Echinococcus granulosus ornithine aminotransferase 0.0071 0.0302 0.0585
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0118 0.0276
Brugia malayi hypothetical protein 0.0026 0.0094 0.018
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0088 0.0085
Schistosoma mansoni hypothetical protein 0.041 0.1873 0.4531
Brugia malayi MBOAT family protein 0.0021 0.0069 0.013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.0826 0.1995
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0499 0.2285 0.2284
Onchocerca volvulus 0.002 0.0064 0.0329
Schistosoma mansoni hypothetical protein 0.002 0.0064 0.0146
Schistosoma mansoni ap endonuclease 0.0018 0.0058 0.0132
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0736 0.3387 0.6755
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0044 0.0176 0.0344
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0049 0.0202 0.0395
Echinococcus granulosus o acyltransferase membrane bound domain 0.0021 0.0069 0.012
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0071 0.0068
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0064 0.011
Loa Loa (eye worm) Smad1 0.0008 0.0012 0.0017
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0326 0.0325
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.0896 0.4128 1
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0008 0.001 0.0012
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0049 0.0202 0.0395
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0004 0.0037
Brugia malayi Inositol-1 0.0039 0.0152 0.0297
Loa Loa (eye worm) hypothetical protein 0.0021 0.0071 0.0135
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0021 0.0069 0.2037
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0012
Leishmania major protein kinase A catalytic subunit 0.0021 0.0069 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Trichomonas vaginalis porcupine, putative 0.0021 0.0069 0.0068
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0058 0.1827
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0326 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0069 0.0068
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0012 0.0006
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0326 0.0339
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0064 0.011
Schistosoma mansoni hypothetical protein 0.0012 0.0027 0.0057
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0326 0.059
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0008 0.001 0.0012
Brugia malayi MH1 domain containing protein 0.0008 0.0012 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0012 0.002
Plasmodium falciparum zinc finger protein, putative 0.0007 0.0005 0.0031
Trypanosoma brucei ISWI complex protein 0.0006 0.0001 0.0011
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0499 0.2285 0.2813
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0088 1
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0004 0.0037
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0227 0.0436
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0008 0.001 0.0009
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0071 0.0164
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.1136 0.2253
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0184 0.0826 0.1642
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0008 0.001 0.0009
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0543 0.1307
Leishmania major carbonic anhydrase family protein, putative 0.0896 0.4128 1
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.001 0.0012
Leishmania major carbonic anhydrase-like protein 0.0216 0.0976 0.2357
Echinococcus granulosus carbonic anhydrase II 0.0216 0.0976 0.1932
Schistosoma mansoni lipoxygenase 0.0055 0.0227 0.0542
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.012
Echinococcus granulosus serine:threonine protein kinase N2 0.0036 0.0139 0.026
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0021 0.0069 0.013
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.013
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0008 0.001 0.0002
Toxoplasma gondii hypothetical protein 0.0049 0.0202 0.4137
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0064 0.1866
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0082 0.0827
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0382 0.0756
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0152 0.0151
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0118 0.0217
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0072 0.0125
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0058 0.0585
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0069 0.0068
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0021 0.0069 0.0711
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0012
Brugia malayi Muscleblind-like protein 0.1087 0.5013 1
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0004
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0008 0.001 0.0002
Schistosoma mansoni carbonic anhydrase-related 0.0049 0.0202 0.048
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0049 0.0202 0.0395
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0094 0.3027
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0049 0.0202 0.0395
Brugia malayi beta-lactamase family protein 0.0076 0.0326 0.0645
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.002
Mycobacterium ulcerans L-lysine aminotransferase 0.0071 0.0302 0.0298
Loa Loa (eye worm) hypothetical protein 0.0049 0.0202 0.0395
Brugia malayi hypothetical protein 0.002 0.0064 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0033 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0004 0.0026
Loa Loa (eye worm) MBOAT family protein 0.0021 0.0069 0.013
Brugia malayi MBOAT family protein 0.024 0.1084 0.2156
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.001 0.0012
Echinococcus multilocularis dnaJ subfamily B 0.041 0.1873 0.3724
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0107 0.1097
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0326 0.0325
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0021 0.0069 0.012
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0058 0.0132
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0382 0.0746
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0071 0.0302 0.0298
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0058 0.013
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0088 0.0085
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0487 0.223 0.2744
Loa Loa (eye worm) carbonic anhydrase 3 0.0216 0.0976 0.194
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0058 0.0585
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0216 0.0976 0.2357
Loa Loa (eye worm) AGC/PKA protein kinase 0.0021 0.0069 0.0131
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0071 0.0162
Trypanosoma cruzi glycerol uptake protein, putative 0.0021 0.0069 0.0695
Trypanosoma brucei chrX additional, unordered contigs 0.0007 0.0004 0.0037
Loa Loa (eye worm) G protein alpha subunit 3 0.0008 0.001 0.0012
Mycobacterium tuberculosis Probable aminotransferase 0.0499 0.2285 0.2813
Schistosoma mansoni ran 0.0021 0.0072 0.0165
Brugia malayi Smad1 0.0008 0.0012 0.0017
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0058 0.0241 0.2459
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0326 0.0635
Echinococcus granulosus RUN 0.002 0.0064 0.011
Schistosoma mansoni lipoxygenase 0.002 0.0064 0.0146
Echinococcus multilocularis muscleblind protein 1 0.1087 0.5013 1
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0004 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0012 0.0017
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0071 0.0135
Trypanosoma brucei unspecified product 0.0015 0.0041 0.0419
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Loa Loa (eye worm) doublecortin family protein 0.002 0.0064 0.012
Brugia malayi Doublecortin family protein 0.002 0.0064 0.012
Brugia malayi hypothetical protein 0.0251 0.1136 0.2261
Echinococcus multilocularis RUN 0.002 0.0064 0.011
Brugia malayi MBOAT family protein 0.0021 0.0069 0.013
Schistosoma mansoni ap endonuclease 0.0018 0.0058 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.013
Brugia malayi RNA, U transporter 1 0.0082 0.0354 0.0699
Mycobacterium ulcerans hypothetical protein 0.0499 0.2285 0.2282
Echinococcus multilocularis expressed protein 0.0008 0.001 0.0002
Mycobacterium ulcerans carbonic anhydrase 0.0896 0.4128 0.4126
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0082 0.0081
Brugia malayi MH2 domain containing protein 0.0008 0.0012 0.0017
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0008 0.001 0.0002
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0071 0.0302 0.0298
Onchocerca volvulus Putative sulfate transporter 0.0362 0.1653 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0021 0.0069 0.0695
Loa Loa (eye worm) hypothetical protein 0.1087 0.5013 1
Schistosoma mansoni rab6-interacting 0.002 0.0064 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0041 0.0419
Leishmania major hypothetical protein, conserved 0.0021 0.0069 0.0158
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.001 0.0009
Chlamydia trachomatis sulfate transporter 0.0058 0.0241 0.7142
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0008 0.001 0.0015
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0082 0.0081
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0008 0.001 0.0009
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0021 0.0069 0.0701
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0021 0.0069 0.2206
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.001 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0184 0.0826 0.1633
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0008 0.001 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Schistosoma mansoni rab6-interacting 0.002 0.0064 0.0146
Echinococcus multilocularis muscleblind protein 0.1087 0.5013 1
Plasmodium vivax importin-beta 2, putative 0.0029 0.0107 0.3202
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0004 0.0037
Trypanosoma brucei glycerol uptake protein, putative 0.0021 0.0069 0.0706
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0071 0.0302 0.0529
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0071 0.0125
Schistosoma mansoni atypical protein kinase C 0.0008 0.0009 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Entamoeba histolytica carbonic anhydrase, putative 0.0896 0.4128 1
Brugia malayi G-protein alpha subunit 0.0008 0.001 0.0012
Schistosoma mansoni ran 0.0021 0.0072 0.0165
Schistosoma mansoni hypothetical protein 0.0049 0.0202 0.048
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0326 0.0323
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0064 0.011
Mycobacterium ulcerans integral membrane transporter 0.0058 0.0241 0.0237
Onchocerca volvulus 0.0076 0.0326 0.1927
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0542 0.1074
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.024 0.1084 0.2148
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0118 0.0217
Trichomonas vaginalis AGC family protein kinase 0.0021 0.0069 0.0068
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.1402 0.2791
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0107 0.1097
Giardia lamblia Kinase, AGC PKA 0.0021 0.0069 0.9668
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0837 0.3856 0.7688
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0094 0.018
Brugia malayi hypothetical protein 0.0017 0.0051 0.0095
Leishmania major hypothetical protein, conserved 0.0076 0.0326 0.0783
Echinococcus multilocularis zinc finger protein 0.0219 0.0988 0.1957
Schistosoma mansoni sterol O-acyltransferase 1 0.0021 0.0069 0.0158
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0216 0.0976 0.2357
Entamoeba histolytica PH domain containing protein kinase, putative 0.0021 0.0069 0.0157
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.072
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0071 0.0302 0.0308
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0021 0.0069 0.012
Trichomonas vaginalis ran, putative 0.0021 0.0072 0.0071
Brugia malayi Hhat protein 0.0021 0.0069 0.013
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0008 0.001 0.0012
Schistosoma mansoni myst-related protein 0.0007 0.0005 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0008 0.001 0.0015
Echinococcus multilocularis dna polymerase eta 0.0021 0.0071 0.0125
Echinococcus granulosus importin subunit beta 1 0.0029 0.0107 0.0196
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0008 0.001 0.0012
Onchocerca volvulus 0.0088 0.0382 0.2266
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0071 0.0302 0.0595
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0044 0.0099
Onchocerca volvulus 0.0362 0.1653 1
Trypanosoma brucei carbonic anhydrase-like protein 0.0216 0.0976 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0134 0.0112
Echinococcus granulosus zinc finger protein 0.0219 0.0988 0.1957
Echinococcus granulosus Protein kinase C brain isozyme 0.0008 0.0012 0.0006
Schistosoma mansoni carbonic anhydrase-related 0.0049 0.0202 0.048
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0326 0.0339
Echinococcus multilocularis carbonic anhydrase 0.0049 0.0202 0.0385
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0021 0.0069 0.012
Brugia malayi CXXC zinc finger family protein 0.0057 0.0239 0.047
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0021 0.0069 0.0158
Echinococcus multilocularis carbonic anhydrase 0.0049 0.0202 0.0385
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0008 0.001 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0118 0.0217
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0542 0.1074
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0008 0.0012 0.0006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.021 0.0413
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0152 0.0358
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0021 0.0069 0.0158
Echinococcus multilocularis carbonic anhydrase 0.0049 0.0202 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0012 0.0006
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0072 0.0136
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0071 0.0731
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0071 0.0302 0.0529
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0012
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.0459 0.2101 0.2581
Entamoeba histolytica PH domain containing protein kinase, putative 0.0021 0.0069 0.0157
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0326 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0326 0.0323
Trypanosoma cruzi GUP1, putative 0.0021 0.0069 0.0695
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0008 0.001 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0071 0.072
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.0976 0.194
Echinococcus multilocularis sterol O acyltransferase 1 0.0021 0.0069 0.012
Mycobacterium tuberculosis Conserved protein 0.0076 0.0326 0.0339
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0072 0.0734
Loa Loa (eye worm) hypothetical protein 0.0029 0.0107 0.0206
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0071 0.0302 0.0723
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0021 0.0069 0.0711
Brugia malayi protein kinase C II. 0.0044 0.0176 0.0344
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0008 0.001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0239 0.047
Echinococcus granulosus cpg binding protein 0.0061 0.0254 0.0491
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0008 0.001 0.0002
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0021 0.0069 0.012
Mycobacterium ulcerans lipase LipD 0.0076 0.0326 0.0323
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0072 0.0724
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0044 0.0071
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0071 0.0017
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0152 0.3867
Trichomonas vaginalis set domain proteins, putative 0.0238 0.1079 0.1078
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0071 0.0731
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0082 0.0081
Brugia malayi diacylglycerol acyltransferase 0.0021 0.0069 0.013
Echinococcus multilocularis ornithine aminotransferase 0.0071 0.0302 0.0585
Echinococcus granulosus smad 0.0008 0.0012 0.0006
Brugia malayi Pre-SET motif family protein 0.0031 0.0118 0.0228
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0008 0.001 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.2163 1 1
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.001 0.0009
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0088 0.1766
Echinococcus granulosus sterol O acyltransferase 1 0.0021 0.0069 0.012
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.002 0.0068 0.0118
Schistosoma mansoni survival motor neuron protein 0.0051 0.021 0.0501
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0071 0.0164
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0021 0.0069 0.0121
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0094 0.0952
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0008 0.001 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0033 0.0032
Toxoplasma gondii AGC kinase 0.0021 0.0069 0.1374
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0071 0.0731
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0072 0.0724
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0021 0.0069 0.0156
Mycobacterium ulcerans beta-lactamase 0.0076 0.0326 0.0323
Schistosoma mansoni myst-related protein 0.0007 0.0005 0.0002
Trypanosoma brucei unspecified product 0.0015 0.0041 0.0419
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0008 0.001 0.0015
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0008 0.001 0.0012
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0326 0.0339
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0088 0.0205
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0008 0.001 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0004 0.0037
Echinococcus granulosus Smad4 0.0008 0.0012 0.0006
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0152 0.0361
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0061 0.0114
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0044 0.0071
Brugia malayi Importin beta-1 subunit 0.0029 0.0107 0.0206
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0021 0.0069 0.0156
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0058 0.0109
Echinococcus multilocularis snurportin 1 0.0308 0.1402 0.2784
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0058 0.8007
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0071 0.007
Schistosoma mansoni cpg binding protein 0.0057 0.0239 0.0571
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0021 0.0069 0.012
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.012
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0152 0.0149
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0021 0.0069 0.0701
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0064 0.011
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0071 0.0068
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.002
Schistosoma mansoni carbonic anhydrase-related 0.0049 0.0202 0.048
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0069 0.0156
Toxoplasma gondii inorganic anion transporter, sulfate permease (SulP) family protein 0.0058 0.0241 0.4952
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0326 0.0339
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0227 0.0436
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0058 0.0057
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0152 0.3106
Loa Loa (eye worm) hypothetical protein 0.0251 0.1136 0.2261
Leishmania major protein kinase A catalytic subunit isoform 2 0.0021 0.0069 0.0159
Schistosoma mansoni hypothetical protein 0.0051 0.021 0.0501
Loa Loa (eye worm) AGC/PKA protein kinase 0.0021 0.0069 0.0131
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0064 0.011
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0094 0.2795
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0021 0.0069 0.0131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0033 0.0032
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0012 0.0017
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0021 0.0069 0.0121
Leishmania major protein kinase A catalytic subunit isoform 1 0.0021 0.0069 0.0159
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0064 0.2021
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0008 0.001 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0184 0.0826 0.1995
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0008 0.001 0.0009
Brugia malayi MH1 domain containing protein 0.0008 0.0012 0.0017

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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