Detailed information for compound 651460

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 279.293 | Formula: C16H13N3O2
  • H donors: 3 H acceptors: 2 LogP: 2.6 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cccc(c1)C(=O)N/N=C/c1c[nH]c2c1cccc2
  • InChi: 1S/C16H13N3O2/c20-13-5-3-4-11(8-13)16(21)19-18-10-12-9-17-15-7-2-1-6-14(12)15/h1-10,17,20H,(H,19,21)/b18-10+
  • InChiKey: SKXOLXVGBYDJDU-VCHYOVAHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0023 0.1013
Brugia malayi PHD-finger family protein 0.0011 0.0007 0.0009
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0216 0.0215
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0025 0.0023
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0254 0.1982
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0047 0.0058
Onchocerca volvulus 0.0096 0.0352 0.3659
Schistosoma mansoni regulator of G protein signaling 0.0194 0.0748 0.0952
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0006
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0194 0.0748 0.095
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.018 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0081 0.3372
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Schistosoma mansoni alpha-glucosidase 0.0158 0.0604 0.0769
Onchocerca volvulus Protein patched homolog 0.0018 0.0035 0.0135
Brugia malayi G-protein coupled receptor 0.004 0.0125 0.0159
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0077 0.0107
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0025 0.0023
Toxoplasma gondii exonuclease III APE 0.0021 0.0047 0.1967
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0043 0.0041
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0194 0.0748 0.0952
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0043 0.0058
Brugia malayi AKH receptor 0.004 0.0125 0.0159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0171 0.0217
Schistosoma mansoni regulator of G protein signaling 0.0194 0.0748 0.0952
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0043 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0127 0.0451
Echinococcus multilocularis axis inhibition protein axin 0.0194 0.0748 0.0746
Brugia malayi Patched protein homolog 1 0.0018 0.0035 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0187 0.0714
Echinococcus granulosus g protein coupled receptor 0.004 0.0125 0.0174
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0047 0.006
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0047 0.0059
Schistosoma mansoni neuropeptide f receptor 76f 0.004 0.0125 0.0159
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0254 0.1982
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0002 0.0003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0002 0.0098
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0113 0.0141
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0047 0.2349
Schistosoma mansoni alpha-1 adrenergic receptor 0.004 0.0125 0.0159
Echinococcus multilocularis neuropeptide receptor 0.004 0.0125 0.0123
Schistosoma mansoni hypothetical protein 0.0096 0.0352 0.0448
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.004 0.0125 0.0123
Onchocerca volvulus Protein patched homolog 0.0018 0.0035 0.0135
Entamoeba histolytica hypothetical protein 0.0113 0.0419 0.1791
Echinococcus multilocularis dro:myosuppressin receptor 0.004 0.0125 0.0123
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0187 0.0186
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0041 0.0039
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1749 0.7066 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.004 0.0125 0.0157
Echinococcus multilocularis biogenic amine (5HT) receptor 0.004 0.0125 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0125 0.0174
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.004 0.0125 0.0159
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0125 0.0123
Echinococcus multilocularis sterol regulatory element binding protein 0.0129 0.0484 0.0482
Schistosoma mansoni topbp1 0.002 0.0041 0.0052
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0043 0.0052
Echinococcus multilocularis G protein coupled receptor 139 0.004 0.0125 0.0123
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0047 0.02
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0047 0.0059
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0047 0.0058
Schistosoma mansoni hypothetical protein 0.0073 0.0257 0.0327
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0194 0.0748 0.0746
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.004 0.0125 0.0157
Echinococcus granulosus neutral alpha glucosidase AB 0.0041 0.0127 0.0177
Schistosoma mansoni neuropeptide receptor 0.004 0.0125 0.0159
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.004 0.0125 0.0157
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.004 0.0125 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0043 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Echinococcus granulosus GPCR family 2 0.0034 0.0098 0.0136
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0128 0.0126
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0105
Brugia malayi Patched related family protein 4 0.0018 0.0035 0.0044
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0025 0.1345
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0043 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0216 0.0276
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0158 0.0602 0.0764
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0025 0.1054
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0041 0.2171
Echinococcus granulosus allatostatin A receptor 0.004 0.0125 0.0174
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0084 0.0117
Brugia malayi gonadotropin-releasing hormone receptor 2 0.004 0.0125 0.0159
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0043 0.0041
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0047 0.2512
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0125 0.0174
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.004 0.0125 0.0174
Schistosoma mansoni DNA helicase recq5 0.0021 0.0045 0.0058
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0041 0.1936
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0125 0.0159
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0047 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0043 0.0054
Echinococcus multilocularis neuropeptide receptor A26 0.0506 0.2016 0.2014
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0187 0.0186
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0239 0.0237
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.0394 0.0502
Schistosoma mansoni neuropeptide receptor 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0043 0.0054
Echinococcus granulosus intermediate filament protein 0.003 0.0084 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0216 0.0276
Echinococcus granulosus nibrin 0.002 0.0041 0.0055
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0045 0.1902
Echinococcus multilocularis sex peptide receptor 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0125 0.0123
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0047 0.0058
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0043 0.0054
Echinococcus multilocularis allatostatin A receptor 0.004 0.0125 0.0123
Echinococcus granulosus peregrin 0.0029 0.0081 0.0112
Onchocerca volvulus 0.003 0.0084 0.0688
Brugia malayi hypothetical protein 0.0113 0.0419 0.0534
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0125 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0168 0.1308
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0081 0.4404
Loa Loa (eye worm) hypothetical protein 0.005 0.0162 0.0204
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Loa Loa (eye worm) oxidoreductase 0.0021 0.0047 0.0058
Treponema pallidum fructose-bisphosphate aldolase 0.0583 0.2331 1
Echinococcus granulosus X box binding protein 1 0.0286 0.1124 0.1588
Loa Loa (eye worm) hypothetical protein 0.0194 0.0748 0.095
Giardia lamblia Fructose-bisphosphate aldolase 0.0583 0.2331 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.018 0.0227
Brugia malayi Glycosyl hydrolases family 31 protein 0.0041 0.0127 0.0161
Schistosoma mansoni myosin xvIII 0.004 0.0125 0.0159
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.0194 0.0748 0.095
Onchocerca volvulus 0.004 0.0125 0.1138
Echinococcus granulosus orexin receptor type 2 0.004 0.0125 0.0174
Schistosoma mansoni regulator of G protein signaling 0.0194 0.0748 0.0952
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0285 0.1119 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.0171 0.0215
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0127 0.0533
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0047 0.006
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.004 0.0125 0.0174
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0254 1
Schistosoma mansoni growth hormone secretagogue receptor 0.004 0.0125 0.0159
Brugia malayi TAR-binding protein 0.0063 0.0216 0.0276
Schistosoma mansoni rab6-interacting 0.002 0.0043 0.0055
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0045 0.2428
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0047 0.1055
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis fatty acid binding protein FABP2 0.0066 0.0229 0.0227
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi Serotonin/octopamine receptor family protein 7 0.004 0.0125 0.0159
Echinococcus multilocularis Niemann Pick C1 protein 0.03 0.118 0.1178
Echinococcus granulosus survival motor neuron protein 1 0.0472 0.1878 0.2657
Echinococcus multilocularis axis inhibition protein axin 0.0194 0.0748 0.0746
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.004 0.0052
Brugia malayi STAT protein, DNA binding domain containing protein 0.0159 0.0606 0.0772
Schistosoma mansoni polycystin 1-related 0.002 0.0043 0.0055
Echinococcus multilocularis g protein coupled receptor 0.004 0.0125 0.0123
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0041 0.1701
Schistosoma mansoni hypothetical protein 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0047 0.2513
Schistosoma mansoni hypothetical protein 0.004 0.0125 0.0159
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0239 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0098 0.0096
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni lipoxygenase 0.002 0.0043 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0216 0.0276
Echinococcus multilocularis g protein coupled receptor 0.004 0.0125 0.0123
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0043 0.0041
Onchocerca volvulus 0.004 0.0125 0.1138
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0047 0.1056
Brugia malayi G protein-coupled receptor 0.004 0.0125 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0045 0.0099
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0168 0.1308
Schistosoma mansoni peptide (allatostatin)-like receptor 0.004 0.0125 0.0159
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0043 0.0225
Schistosoma mansoni hypothetical protein 0.002 0.0043 0.0055
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0043 0.0041
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0098 0.0136
Toxoplasma gondii hypothetical protein 0.0018 0.0035 0.1453
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.0058
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0066 0.0229 0.0289
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.005
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0043 0.0058
Brugia malayi G-protein coupled receptor 0.004 0.0125 0.0159
Onchocerca volvulus 0.0029 0.0079 0.0625
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0045 0.0099
Loa Loa (eye worm) hypothetical protein 0.0015 0.002 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0043 0.0054
Brugia malayi RNA binding protein 0.0063 0.0216 0.0276
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1749 0.7066 0.7065
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.004 0.0125 0.1138
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0041 0.0078
Echinococcus multilocularis X box binding protein 1 0.0286 0.1124 0.1122
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0254 0.1082
Schistosoma mansoni axis inhibition protein axin 0.0194 0.0748 0.0952
Onchocerca volvulus 0.004 0.0125 0.1138
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0025 0.1286
Brugia malayi hypothetical protein 0.002 0.0041 0.0052
Schistosoma mansoni biogenic amine receptor 0.004 0.0125 0.0159
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0047 0.0059
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0125 0.0159
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0025 0.0023
Schistosoma mansoni hypothetical protein 0.0124 0.0465 0.0592
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0166 0.0209
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0041 0.1701
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0187 0.064
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0098 0.0122
Loa Loa (eye worm) doublecortin family protein 0.002 0.0043 0.0052
Schistosoma mansoni microtubule-associated protein tau 0.1377 0.5557 0.7076
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Echinococcus granulosus expressed protein 0.0194 0.0748 0.1056
Entamoeba histolytica hypothetical protein 0.0194 0.0748 0.3202
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Loa Loa (eye worm) PXA domain-containing protein 0.0194 0.0748 0.095
Echinococcus multilocularis tumor protein p63 0.0339 0.1337 0.1336
Leishmania major alpha glucosidase II subunit, putative 0.0041 0.0127 0.4487
Brugia malayi hypothetical protein 0.002 0.0043 0.0055
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0191 0.0189
Schistosoma mansoni alpha glucosidase 0.0041 0.0127 0.0161
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0113 0.0143
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0047 0.006
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0184 0.0708 0.0899
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0254 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0353 0.0498
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0047 0.1966
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0025 0.1345
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0127 0.0451
Schistosoma mansoni hypothetical protein 0.0113 0.0419 0.0534
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0043 0.2281
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0041 0.0127 0.0533
Schistosoma mansoni hypothetical protein 0.0034 0.0098 0.0125
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0047 0.02
Echinococcus multilocularis serotonin receptor 0.004 0.0125 0.0123
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0125 0.0174
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0187 0.7833
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0125 0.0174
Brugia malayi putative neuropeptide receptor NPR1 0.004 0.0125 0.0159
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Loa Loa (eye worm) hypothetical protein 0.0072 0.0254 0.0322
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.0394 0.05
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0125 0.0174
Echinococcus granulosus tumor protein p63 0.0339 0.1337 0.1891
Schistosoma mansoni alpha-glucosidase 0.0158 0.0604 0.0769
Trichomonas vaginalis set domain proteins, putative 0.0237 0.0923 0.39
Schistosoma mansoni histamine h1 receptor 0.004 0.0125 0.0159
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0047 0.2304
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0171 0.0217
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0047 0.1966
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0047 0.2347
Echinococcus multilocularis expressed conserved protein 0.0282 0.1106 0.1104
Onchocerca volvulus 0.004 0.0125 0.1138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0043 0.0052
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0191 0.0267
Echinococcus granulosus FTZ F1 alpha 0.002 0.0043 0.0058
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0041 0.0127 0.5292
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0127 0.0451
Echinococcus granulosus g-protein coupled receptor 0.004 0.0125 0.0174
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0047 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0194 0.0748 0.3143
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0035 0.009
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0045 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Schistosoma mansoni biogenic amine (5HT) receptor 0.004 0.0125 0.0159
Schistosoma mansoni amine GPCR 0.004 0.0125 0.0159
Giardia lamblia PHD finger protein 15 0.0029 0.0081 0.0175
Schistosoma mansoni adenoreceptor 0.004 0.0125 0.0159
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0047 0.1966
Brugia malayi hypothetical protein 0.0018 0.0035 0.0044
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0041 0.2156
Entamoeba histolytica hypothetical protein 0.0113 0.0419 0.1791
Echinococcus granulosus alpha 1A adrenergic receptor 0.004 0.0125 0.0174
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0084 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Loa Loa (eye worm) STAT protein 0.0159 0.0606 0.077
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0041 0.0078
Onchocerca volvulus 0.002 0.0043 0.0225
Echinococcus granulosus 7tm_1 domain containing protein 0.004 0.0125 0.0174
Echinococcus multilocularis Regulator of G protein signaling 20 0.0194 0.0748 0.0746
Brugia malayi Tachykinin-like peptides receptor 99D 0.004 0.0125 0.0159
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0098 0.0096
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0098 0.0136
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.0254 0.1982
Onchocerca volvulus 0.0106 0.0393 0.4113
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Loa Loa (eye worm) hypothetical protein 0.0107 0.0394 0.05
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Brugia malayi hypothetical protein 0.0472 0.1878 0.2392
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0187 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0239 0.1842
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0041 0.0078
Echinococcus granulosus lamin 0.003 0.0084 0.0117
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0239 0.1842
Loa Loa (eye worm) RGS-3 protein 0.0194 0.0748 0.095
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0239 0.0336
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0084 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0041 0.0078
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0084 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Brugia malayi nuclear receptor RXR 0.0011 0.0004 0.0005
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0035 0.1593
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0187 0.0263
Loa Loa (eye worm) hypothetical protein 0.003 0.0082 0.0102
Echinococcus granulosus bloom syndrome protein 0.0021 0.0045 0.0062
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0041 0.0127 0.0159
Onchocerca volvulus 0.004 0.0125 0.1138
Schistosoma mansoni rab6-interacting 0.002 0.0043 0.0055
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0025 0.0023
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0305 0.1199 0.1526
Schistosoma mansoni nuclear hormone receptor 0.002 0.0043 0.0054
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0187 0.0236
Brugia malayi Melatonin receptor type 1A 0.004 0.0125 0.0159
Echinococcus granulosus neuropeptide receptor 0.004 0.0125 0.0174
Echinococcus multilocularis somatostatin receptor 0.004 0.0125 0.0123
Trichomonas vaginalis sucrase-isomaltase, putative 0.0041 0.0127 0.0451
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0047 0.006
Brugia malayi DKFZp564C0469 protein 0.002 0.0041 0.0052
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0045 0.0099
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0004 0.0005
Brugia malayi CHE-14 protein 0.0129 0.0484 0.0616
Brugia malayi Dopamine receptor 0.004 0.0125 0.0159
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0125 0.0174
Echinococcus granulosus g protein coupled receptor 0.004 0.0125 0.0174
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0045 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0043 0.0054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0171 0.0169
Brugia malayi hypothetical protein 0.0018 0.0035 0.0044
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0419 0.0534
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) melatonin receptor type 1A 0.004 0.0125 0.0157
Schistosoma mansoni hypothetical protein 0.0286 0.1124 0.1431
Schistosoma mansoni loxhd1 0.002 0.0043 0.0055
Schistosoma mansoni intermediate filament proteins 0.003 0.0084 0.0108
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0047 0.0192
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.018 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.018 0.1294
Echinococcus granulosus fatty acid binding protein FABP2 0.0066 0.0229 0.0321
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0047 0.02
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Schistosoma mansoni z-protein (S1r protein) 0.0194 0.0748 0.0952
Onchocerca volvulus Alhambra homolog 0.0029 0.0081 0.0645
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.005
Onchocerca volvulus 0.0021 0.0047 0.0272
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0171 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0484 0.1998
Brugia malayi Bromodomain containing protein 0.0029 0.0081 0.0103
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.005
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0047 0.0106
Brugia malayi hypothetical protein 0.0011 0.0004 0.0005
Echinococcus multilocularis expressed protein 0.0194 0.0748 0.0746
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0045 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0769 0.0979
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0047 0.006
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0045 0.0058
Schistosoma mansoni ap endonuclease 0.0021 0.0047 0.006
Echinococcus multilocularis protein dispatched 1 0.0147 0.0558 0.0556
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0025 0.1157
Echinococcus multilocularis G-protein coupled receptor, putative 0.004 0.0125 0.0123
Echinococcus granulosus neuropeptides capa receptor 0.004 0.0125 0.0174
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0239 0.1957
Loa Loa (eye worm) hypothetical protein 0.0072 0.0254 0.0322
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0047 0.0059
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0005
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0047 0.006
Onchocerca volvulus 0.003 0.0084 0.0686
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Brugia malayi regulator of G-protein signaling rgs-7 0.0194 0.0748 0.0952
Echinococcus multilocularis g-protein coupled receptor 0.004 0.0125 0.0123
Echinococcus multilocularis lamin dm0 0.003 0.0084 0.0083
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0257 0.0327
Trypanosoma brucei glucosidase, putative 0.0041 0.0127 0.6756
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni amine GPCR 0.004 0.0125 0.0159
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0047 0.2349
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.004 0.0125 0.0174
Entamoeba histolytica hypothetical protein 0.0194 0.0748 0.3202
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0043 0.0054
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0451 0.0573
Loa Loa (eye worm) follicle stimulating hormone receptor 0.004 0.0125 0.0157
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0047 0.0045
Echinococcus multilocularis fmrfamide receptor 0.004 0.0125 0.0123
Brugia malayi larval opioid receptor 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0043 0.0041
Schistosoma mansoni DNA helicase recq1 0.0021 0.0045 0.0058
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0239 0.0305
Trichomonas vaginalis conserved hypothetical protein 0.0194 0.0748 0.3143
Echinococcus granulosus axis inhibition protein axin 0.0194 0.0748 0.1056
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0194 0.0748 0.3143
Onchocerca volvulus 0.004 0.0125 0.1138
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0025 0.0032
Onchocerca volvulus 0.004 0.0125 0.1138
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0171 0.0169
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0047 0.0059
Plasmodium falciparum phd finger protein, putative 0.0029 0.0081 0.4247
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Echinococcus multilocularis Niemann Pick C1 protein 0.0429 0.1703 0.1701
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.0171 0.0217
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0043 0.0041
Echinococcus multilocularis nibrin 0.002 0.0041 0.0039
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0162 0.0207
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0043 0.0054
Entamoeba histolytica hypothetical protein 0.002 0.0041 0.0165
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0254 0.1982
Echinococcus multilocularis peregrin 0.0029 0.0081 0.0079
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0004 0.0003
Brugia malayi Serotonin receptor 0.004 0.0125 0.0159
Echinococcus multilocularis alpha 1A adrenergic receptor 0.004 0.0125 0.0123
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0107
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0004 0.0167
Loa Loa (eye worm) patched family protein 0.0018 0.0035 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0127 0.0451
Loa Loa (eye worm) hypothetical protein 0.0054 0.018 0.0227
Echinococcus multilocularis neuropeptide Y receptor 0.004 0.0125 0.0123
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0047 0.02
Schistosoma mansoni coup transcription factor 0.002 0.0043 0.0054
Onchocerca volvulus 0.004 0.0125 0.1138
Plasmodium vivax SET domain protein, putative 0.003 0.0084 0.461
Echinococcus granulosus fatty acid binding protein FABP2 0.0066 0.0229 0.0321
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0043 0.0041
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0081 0.3372
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0254 0.1982
Schistosoma mansoni amine GPCR 0.004 0.0125 0.0159
Echinococcus multilocularis tachykinin peptides receptor 99D 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.015 0.0571 0.0725
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Brugia malayi protein C24B5.3 0.0018 0.0035 0.0044
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0239 0.9346
Schistosoma mansoni lamin 0.003 0.0084 0.0108
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0047 0.02
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0047 0.0106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.0194 0.0748 0.095
Entamoeba histolytica recQ family DNA helicase 0.0011 0.0004 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0047 0.02
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0125 0.0159
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0047 0.0059
Brugia malayi nuclear hormone receptor 0.002 0.0043 0.0054
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0047 0.02
Echinococcus granulosus fmrfamide receptor 0.004 0.0125 0.0174
Schistosoma mansoni biogenic amine receptor 0.004 0.0125 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0043 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Brugia malayi Pre-SET motif family protein 0.003 0.0084 0.0107
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0254 0.1082
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0254 0.0324
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0125 0.0157
Loa Loa (eye worm) TYRA-2 protein 0.004 0.0125 0.0157
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0041 0.2001
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0125 0.0174
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0047 0.0059
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0034 0.0043
Echinococcus multilocularis neuropeptide FF receptor 2 0.004 0.0125 0.0123
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0043 0.0054
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.0254 0.1082
Echinococcus granulosus thyrotropin releasing hormone receptor 0.004 0.0125 0.0174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Loa Loa (eye worm) intermediate filament protein 0.003 0.0084 0.0105
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0045 0.0058
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0187 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0025 0.0033
Toxoplasma gondii patched family protein 0.0018 0.0035 0.1453
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0208 0.0263
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0047 0.2302
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0127 0.0451
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0254 0.0324
Onchocerca volvulus 0.004 0.0125 0.1138
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0419 0.0418
Brugia malayi Patched related family protein 12 0.0018 0.0035 0.0044
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0045 0.0044
Schistosoma mansoni cpg binding protein 0.0031 0.0086 0.0109
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0041 0.0052
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0045 0.0062
Onchocerca volvulus 0.0021 0.0047 0.0272
Echinococcus multilocularis regulator of G protein signaling 3 0.0194 0.0748 0.0746
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Trichomonas vaginalis maltase-glucoamylase, putative 0.0041 0.0127 0.0451
Echinococcus granulosus axis inhibition protein axin 0.0194 0.0748 0.1056
Schistosoma mansoni hypothetical protein 0.0891 0.3581 0.456
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0041 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0043 0.0054
Loa Loa (eye worm) hypothetical protein 0.0073 0.0257 0.0325
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0451 0.0573
Echinococcus granulosus regulator of G protein signaling 3 0.0194 0.0748 0.1056
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Loa Loa (eye worm) hypothetical protein 0.03 0.118 0.15
Echinococcus granulosus Regulator of G protein signaling 20 0.0194 0.0748 0.1056
Brugia malayi neuropeptide F receptor 0.004 0.0125 0.0159
Brugia malayi Glycosyl hydrolases family 31 protein 0.0184 0.0708 0.0901
Brugia malayi A-kinase anchor protein 10, precursor 0.0194 0.0748 0.0952
Schistosoma mansoni hypothetical protein 0.0124 0.0465 0.0592
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0806 0.1025
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0041 0.0078
Onchocerca volvulus 0.002 0.0041 0.0201
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0125 0.0123
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0353 0.0352
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0125 0.0174
Echinococcus granulosus replication factor c subunit 1 0.002 0.0041 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0043 0.0058
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.004 0.0125 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0125 0.0174
Schistosoma mansoni regulator of G protein signaling 0.0194 0.0748 0.0952
Onchocerca volvulus 0.0018 0.0035 0.0135
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0047 0.2515
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0041 0.0078
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0047 0.02
Loa Loa (eye worm) RNA binding protein 0.0063 0.0216 0.0273
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0125 0.0159
Echinococcus granulosus cpg binding protein 0.0031 0.0086 0.0119
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0023 0.0087
Schistosoma mansoni topbp1 0.002 0.0041 0.0052
Echinococcus granulosus dnaJ subfamily B 0.0891 0.3581 0.5066
Onchocerca volvulus 0.002 0.0043 0.0226
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0047 0.02
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0025 0.003
Onchocerca volvulus 0.004 0.0125 0.1138
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0047 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0098 0.0122
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0168 0.1308
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Loa Loa (eye worm) patched family protein 0.0018 0.0035 0.0042
Brugia malayi PXA domain containing protein 0.0194 0.0748 0.0952
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0194 0.0748 0.3143
Echinococcus granulosus beta-adrenergic receptor kinase 0.0199 0.0769 0.1086
Plasmodium vivax patched family protein, putative 0.0018 0.0035 0.1823
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Echinococcus granulosus hypothetical protein 0.004 0.0125 0.0174
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0125 0.0159
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1749 0.7066 0.8998
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1749 0.7066 0.8997
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0106 0.0104
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0043 0.0058
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0047 0.0028
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0081 0.0103
Echinococcus multilocularis regulator of G protein signaling 0.0194 0.0748 0.0746
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.004 0.0125 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0769 0.0979
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0047 0.2347
Echinococcus granulosus serotonin receptor 0.004 0.0125 0.0174
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0043 0.0052
Loa Loa (eye worm) RecQ helicase 0.0021 0.0045 0.0056
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis survival motor neuron protein 1 0.0472 0.1878 0.1877
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0113 0.0157
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0125 0.0157
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0081 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0043 0.0054
Echinococcus granulosus expressed conserved protein 0.0282 0.1106 0.1563
Loa Loa (eye worm) patched family protein 0.0018 0.0035 0.0042
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0098 0.0125
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0004 0.0092
Echinococcus granulosus regulator of G protein signaling 7 0.0194 0.0748 0.1056
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0125 0.0174
Schistosoma mansoni hypothetical protein 0.0124 0.0465 0.0592
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0047 0.0106
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0254 0.1982
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0583 0.2331 1
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0043 0.0225
Brugia malayi ecdysteroid receptor 0.002 0.0043 0.0054
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0239 0.1842
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0047 0.02
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0041 0.0078
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.004 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Echinococcus granulosus neuropeptide s receptor 0.0506 0.2016 0.2851
Schistosoma mansoni axis inhibition protein axin 0.0194 0.0748 0.0952
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0043 0.0058
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0047 0.0106
Echinococcus multilocularis neuropeptides capa receptor 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0045 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0187 0.0714
Toxoplasma gondii patched family protein 0.0018 0.0035 0.1453
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0043 0.0054
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0056
Brugia malayi RE15519p 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0105
Echinococcus granulosus lysosomal alpha glucosidase 0.0184 0.0708 0.0999
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0043 0.0225
Loa Loa (eye worm) patched family protein 0.0018 0.0035 0.0042
Onchocerca volvulus 0.0018 0.0035 0.0135
Treponema pallidum DNA ligase (lig) 0.002 0.0041 0.0158
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi CXXC zinc finger family protein 0.0029 0.0079 0.01
Schistosoma mansoni serine/threonine protein kinase 0.1942 0.7853 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0047 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0187 0.0714
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Echinococcus multilocularis g protein coupled receptor 0.004 0.0125 0.0123
Echinococcus multilocularis dnaJ subfamily B 0.0891 0.3581 0.358
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0216 0.0273
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0026
Brugia malayi nuclear receptor NHR-88 0.002 0.0043 0.0054
Onchocerca volvulus 0.0018 0.0035 0.0135
Echinococcus granulosus tachykinin peptides receptor 99D 0.004 0.0125 0.0174
Onchocerca volvulus 0.0018 0.0035 0.0135
Brugia malayi PHD-finger family protein 0.0029 0.0081 0.0103
Onchocerca volvulus 0.004 0.0125 0.1138
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Echinococcus granulosus peptide allatostatin:somatostatin 0.004 0.0125 0.0174
Entamoeba histolytica hypothetical protein 0.0194 0.0748 0.3202
Echinococcus granulosus regulator of G protein signaling 3 0.0194 0.0748 0.1056
Echinococcus multilocularis RUN 0.002 0.0043 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0107
Brugia malayi hypothetical protein 0.0018 0.0035 0.0044
Schistosoma mansoni lamin 0.003 0.0084 0.0108
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.004 0.0125 0.0159
Brugia malayi hypothetical protein 0.0194 0.0748 0.0952
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0043 0.0041
Schistosoma mansoni cpg binding protein 0.0029 0.0079 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0043 0.0052
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0025 0.1054
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Onchocerca volvulus 0.005 0.0162 0.1552
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Onchocerca volvulus 0.004 0.0125 0.1138
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0007 0.0273
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0047 0.0059
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0047 0.0059
Onchocerca volvulus 0.004 0.0125 0.1138
Echinococcus multilocularis serotonin receptor 0.004 0.0125 0.0123
Brugia malayi Patched related family protein 10 0.0018 0.0035 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0041 0.2001
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0047 0.1055
Schistosoma mansoni amine GPCR 0.004 0.0125 0.0159
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0171 0.0239
Schistosoma mansoni opsin-like receptor 0.004 0.0125 0.0159
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0254 0.1982
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0187 0.7109
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0171 0.0239
Brugia malayi jmjC domain containing protein 0.0037 0.0113 0.0143
Brugia malayi hypothetical protein 0.015 0.0571 0.0727
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0047 0.006
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.002 0.0026
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.004 0.0125 0.0123
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0043 0.0054
Echinococcus granulosus neuropeptide receptor A26 0.0506 0.2016 0.2851
Loa Loa (eye worm) hypothetical protein 0.0029 0.0081 0.01
Echinococcus multilocularis neuropeptide receptor 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.0054 0.018 0.0227
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0043 0.0054
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0025 0.1041
Onchocerca volvulus 0.003 0.0084 0.0688
Schistosoma mansoni amine GPCR 0.004 0.0125 0.0159
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0125 0.0174
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0047 0.1055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0043 0.0054
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1942 0.7853 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0045 0.0044
Schistosoma mansoni opsin-like receptor 0.004 0.0125 0.0159
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.004 0.0125 0.0159
Toxoplasma gondii patched family protein 0.0018 0.0035 0.1453
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0006 0.0004
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0025 0.0032
Echinococcus granulosus tar DNA binding protein 0.0063 0.0216 0.0304
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Schistosoma mansoni cpg binding protein 0.0031 0.0086 0.0109
Echinococcus multilocularis regulator of G protein signaling 7 0.0194 0.0748 0.0746
Schistosoma mansoni survival motor neuron protein 0.0096 0.0352 0.0448
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0194 0.0748 0.0952
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0583 0.2331 1
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0047 0.02
Loa Loa (eye worm) patched family protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.005
Brugia malayi neuropeptide F receptor 0.004 0.0125 0.0159
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0023 0.1204
Schistosoma mansoni patched 1 0.0129 0.0484 0.0616
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0254 0.1982
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi Niemann-Pick C1 protein precursor 0.03 0.118 0.1502
Schistosoma mansoni fatty acid binding protein 0.0066 0.0229 0.0291
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0023 0.0029
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0194 0.0748 0.0746
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0052
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0187 0.7109
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0043 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0187 0.0239
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0066 0.0229 0.0291
Brugia malayi PXA domain containing protein 0.0194 0.0748 0.0952
Brugia malayi topoisomerase 0.002 0.0041 0.0052
Schistosoma mansoni regulator of G protein signaling 0.0194 0.0748 0.0952
Echinococcus granulosus Niemann Pick C1 protein 0.03 0.118 0.1667
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0041 0.0078
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0047 0.006
Schistosoma mansoni biogenic amine receptor 0.004 0.0125 0.0159
Toxoplasma gondii patched family protein 0.0018 0.0035 0.1453
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0041 0.0078
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi intermediate filament protein 0.003 0.0084 0.0108
Echinococcus granulosus somatostatin receptor 0.004 0.0125 0.0174
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.0254 0.1982
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0187 1
Brugia malayi G protein-coupled receptor F59B2.13 0.004 0.0125 0.0159
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0043 0.2065
Echinococcus granulosus neuropeptide FF receptor 2 0.004 0.0125 0.0174
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.018 0.1417
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0025 0.1157
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0216 0.0275
Echinococcus multilocularis regulator of G protein signaling 7 0.0194 0.0748 0.0746
Schistosoma mansoni hypothetical protein 0.0034 0.0098 0.0125
Loa Loa (eye worm) hypothetical protein 0.0194 0.0748 0.095
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0043 0.0054
Echinococcus granulosus Niemann Pick C1 protein 0.0429 0.1703 0.2408
Echinococcus multilocularis lysosomal alpha glucosidase 0.0184 0.0708 0.0706
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0041 0.2001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0025 0.0114
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0194 0.0748 0.0952
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi putative neuropeptide receptor 0.004 0.0125 0.0159
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0189 0.7897
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0128 0.0178
Echinococcus granulosus regulator of G protein signaling 7 0.0194 0.0748 0.1056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.004 0.0125 0.0159
Echinococcus granulosus dro:myosuppressin receptor 0.004 0.0125 0.0174
Schistosoma mansoni hypothetical protein 0.0029 0.0081 0.0103
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.005
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0081 0.0079
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0045 0.2263
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0047 0.0059
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Brugia malayi steroid hormone receptor 0.002 0.0043 0.0054
Schistosoma mansoni thyroid hormone receptor 0.002 0.0043 0.0054
Echinococcus multilocularis neuropeptide s receptor 0.0506 0.2016 0.2014
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0043 0.0054
Onchocerca volvulus 0.004 0.0125 0.1138
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0127 0.6685
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0084 0.3525
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0352 0.0448
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0023 0.1013
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0125 0.0174
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0047 0.251
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0045 0.1902
Schistosoma mansoni DNA ligase IV 0.002 0.0041 0.0052
Brugia malayi isocitrate dehydrogenase 0.0016 0.0025 0.0032
Echinococcus granulosus g protein coupled receptor 0.004 0.0125 0.0174
Mycobacterium ulcerans hypothetical protein 0.0072 0.0254 0.1982
Trichomonas vaginalis conserved hypothetical protein 0.0194 0.0748 0.3143
Loa Loa (eye worm) hypothetical protein 0.0054 0.018 0.0227
Brugia malayi Dopamine receptor protein 1 0.004 0.0125 0.0159
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0254 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.004 0.0125 0.1138
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0047 0.0064
Echinococcus granulosus biogenic amine 5HT receptor 0.004 0.0125 0.0174
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0045 0.2214
Trichomonas vaginalis alpha-glucosidase, putative 0.0041 0.0127 0.0451
Echinococcus multilocularis GPCR, family 2 0.0034 0.0098 0.0096
Echinococcus granulosus tm gpcr rhodopsin 0.004 0.0125 0.0174
Brugia malayi sulfakinin receptor protein 0.004 0.0125 0.0159
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0041 0.0165
Loa Loa (eye worm) hypothetical protein 0.0129 0.0484 0.0614
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.004 0.0125 0.0123
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0098 0.0125
Onchocerca volvulus 0.0018 0.0035 0.0135
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0047 0.2347
Brugia malayi Serotonin receptor 0.004 0.0125 0.0159
Schistosoma mansoni neuropeptide receptor 0.004 0.0125 0.0159
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0045 0.2214
Entamoeba histolytica hypothetical protein 0.0113 0.0419 0.1791
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0047 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0254 0.0324
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0216 0.0276
Schistosoma mansoni opsin-like receptor 0.004 0.0125 0.0159
Schistosoma mansoni neuropeptide receptor 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni hypothetical protein 0.0034 0.0098 0.0125
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0107
Echinococcus granulosus microtubule associated protein 2 0.1377 0.5557 0.7864
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0043 0.0054
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.004 0.0125 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0043 0.0052
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0419 0.0591
Onchocerca volvulus 0.0029 0.0078 0.062
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Onchocerca volvulus 0.004 0.0125 0.1138
Schistosoma mansoni hypothetical protein 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0047 0.251
Brugia malayi Pre-SET motif family protein 0.0208 0.0806 0.1027
Loa Loa (eye worm) hypothetical protein 0.0054 0.018 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0043 0.0054
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.004 0.0125 0.0123
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Schistosoma mansoni hypothetical protein 0.0124 0.0465 0.0592
Brugia malayi ORL1-like opioid receptor 0.004 0.0125 0.0159
Echinococcus granulosus G protein coupled receptor 139 0.004 0.0125 0.0174
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0043 0.0058
Brugia malayi MH2 domain containing protein 0.0121 0.0451 0.0575
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Brugia malayi protein C24B5.3 0.0018 0.0035 0.0044
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0081 0.01
Brugia malayi hypothetical protein 0.0018 0.0035 0.0044
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.004 0.0125 0.0159
Brugia malayi regulator of G-protein signaling egl-10 0.0194 0.0748 0.0952
Brugia malayi Doublecortin family protein 0.002 0.0043 0.0055
Entamoeba histolytica hypothetical protein 0.0113 0.0419 0.1791
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0187 0.0263
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0045 0.0062
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.004 0.0125 0.0157
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0113 0.0143
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0129 0.0484 0.0614
Onchocerca volvulus 0.002 0.0043 0.0226
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi Regulator of G protein signaling domain containing protein 0.0194 0.0748 0.0952
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0041 0.2001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.2331 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0187 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0043 0.0058
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0045 0.0185
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis neutral alpha glucosidase AB 0.0041 0.0127 0.0125
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0043 0.0054
Loa Loa (eye worm) hypothetical protein 0.0194 0.0748 0.095
Brugia malayi Patched family protein 0.0018 0.0035 0.0044
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0047 0.0064
Echinococcus multilocularis lamin 0.003 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0072 0.0254 0.0322
Onchocerca volvulus 0.0237 0.0923 1
Brugia malayi hypothetical protein 0.002 0.0041 0.0052
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.004 0.0125 0.0159
Echinococcus multilocularis beta adrenergic receptor kinase 0.0199 0.0769 0.0767
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0043 0.0058
Brugia malayi jmjC domain containing protein 0.0097 0.0353 0.045
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0047 0.0185
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0027 0.0032
Loa Loa (eye worm) G-protein coupled receptor 0.004 0.0125 0.0157
Schistosoma mansoni hypothetical protein 0.0034 0.0098 0.0125
Onchocerca volvulus 0.0018 0.0035 0.0135
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0127 0.6685
Echinococcus multilocularis fmrfamide receptor 0.004 0.0125 0.0123
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0043 0.0054
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.002 0.0019
Schistosoma mansoni ap endonuclease 0.0021 0.0047 0.006
Echinococcus multilocularis musashi 0.003 0.0084 0.0083
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Onchocerca volvulus 0.004 0.0125 0.1138
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1749 0.7066 0.8997
Onchocerca volvulus 0.0018 0.0035 0.0135
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0043 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0043 0.0052
Echinococcus multilocularis orexin receptor type 2 0.004 0.0125 0.0123
Onchocerca volvulus 0.004 0.0125 0.1138
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0216 0.0273
Brugia malayi hypothetical protein 0.0194 0.0748 0.0952
Echinococcus granulosus neuropeptide Y receptor 0.004 0.0125 0.0174
Echinococcus multilocularis microtubule associated protein 2 0.1377 0.5557 0.5556
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0047 0.0059
Echinococcus granulosus lamin dm0 0.003 0.0084 0.0117
Brugia malayi hypothetical protein 0.0011 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus granulosus neuropeptide receptor 0.004 0.0125 0.0174
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0041 0.0052
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi hypothetical protein 0.004 0.0125 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0043 0.0054
Schistosoma mansoni neuropeptide F-like receptor 0.004 0.0125 0.0159
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0216 0.0276
Echinococcus granulosus 7TM GPCR rhodopsin 0.004 0.0125 0.0174
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0084 0.0105
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.004 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Schistosoma mansoni thyroid hormone receptor 0.002 0.0043 0.0054
Loa Loa (eye worm) hypothetical protein 0.0472 0.1878 0.239
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0239 0.0305
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1942 0.7853 1
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0043 0.0058
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0025 0.0023
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0199 0.0769 0.0977
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0285 0.1119 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0168 0.1308
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0041 0.0127 0.0451
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0004 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0216 0.0276
Loa Loa (eye worm) hypothetical protein 0.0194 0.0748 0.095
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0079 0.0098
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Brugia malayi Myosin head containing protein 0.0018 0.0035 0.0044
Echinococcus granulosus sterol regulatory element binding protein 0.0129 0.0484 0.0682
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0027 0.0034
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0047 0.2347
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Brugia malayi GnHR receptor homolog 0.004 0.0125 0.0159
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0194 0.0748 0.1056
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.03 0.118 0.5056
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Echinococcus granulosus sex peptide receptor 0.004 0.0125 0.0174
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Echinococcus multilocularis lysosomal alpha glucosidase 0.0184 0.0708 0.0706
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0043 0.0041
Echinococcus multilocularis fatty acid binding protein FABP2 0.0066 0.0229 0.0227
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.0394 0.0502
Echinococcus multilocularis cpg binding protein 0.0031 0.0086 0.0084
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0285 0.1119 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus granulosus Protein patched homolog 1 0.0129 0.0484 0.0682
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0187 0.0714
Trypanosoma brucei protein kinase, putative 0.0056 0.0187 1
Onchocerca volvulus 0.015 0.0571 0.6088
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.018 1
Onchocerca volvulus 0.0021 0.0047 0.0272
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Brugia malayi hypothetical protein 0.002 0.0043 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Loa Loa (eye worm) neuropeptide F receptor 0.004 0.0125 0.0157
Onchocerca volvulus 0.0072 0.0254 0.2575
Trichomonas vaginalis conserved hypothetical protein 0.0194 0.0748 0.3143
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0254 0.2096
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.004 0.0125 0.0159
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.004 0.0125 0.0123
Echinococcus granulosus RUN 0.002 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0045 0.0989
Brugia malayi follicle stimulating hormone receptor 0.004 0.0125 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0042
Schistosoma mansoni lipoxygenase 0.0057 0.0191 0.0243
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0043 0.0041
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0047 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0084 0.0107
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0043 0.0041
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.0254 0.2096
Echinococcus multilocularis rhodopsin orphan GPCR 0.004 0.0125 0.0123
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0004 0.0005
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0273 0.0347
Schistosoma mansoni hypothetical protein 0.004 0.0125 0.0159
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0006 0.0006
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0041 0.0052
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0194 0.0748 0.3143
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0047 0.0059
Brugia malayi MAP kinase sur-1 0.0056 0.0187 0.0239
Brugia malayi Dopamine receptor protein 2 0.004 0.0125 0.0159
Schistosoma mansoni fatty acid binding protein 0.0066 0.0229 0.0291
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0187 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0194 0.0748 0.0952
Loa Loa (eye worm) hypothetical protein 0.004 0.0125 0.0157
Echinococcus multilocularis protein patched 0.0129 0.0484 0.0482

Activities

Activity type Activity value Assay description Source Reference
AbsAC0.47_uM (binding) 0.318 uM PubChem BioAssay. Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-01_Inhibitor_Dose_DryPowder_Activity. (absACnn = the concentration at which the curve crosses threshold nn uM) (Class of assay: confirmatory) ChEMBL. No reference
AbsAC1 (functional) = 2.9 uM PubChem BioAssay. Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis & Epilepsy Measured in Biochemical System Using RT-PCR - 7012-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.3753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 10.691 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.99 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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