Detailed information for compound 659757

Basic information

Technical information
  • TDR Targets ID: 659757
  • Name: 3-chloro-N-(2-methyl-5-nitrophenyl)-1-benzoth iophene-2-carboxamide
  • MW: 346.788 | Formula: C16H11ClN2O3S
  • H donors: 1 H acceptors: 3 LogP: 4.93 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1NC(=O)c1sc2c(c1Cl)cccc2)[N+](=O)[O-]
  • InChi: 1S/C16H11ClN2O3S/c1-9-6-7-10(19(21)22)8-12(9)18-16(20)15-14(17)11-4-2-3-5-13(11)23-15/h2-8H,1H3,(H,18,20)
  • InChiKey: KSWAKUNCGSYFAM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-chloro-N-(2-methyl-5-nitro-phenyl)benzothiophene-2-carboxamide
  • 3-chloro-N-(2-methyl-5-nitrophenyl)-2-benzothiophenecarboxamide
  • 3-chloro-N-(2-methyl-5-nitro-phenyl)-1-benzothiophene-2-carboxamide
  • Oprea1_429659
  • ZINC04644254
  • Oprea1_779069
  • 3-Chloro-benzo[b]thiophene-2-carboxylic acid (2-methyl-5-nitro-phenyl)-amide
  • BAS 00001958

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0026 0.0163 0.1738
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0016 0.0061 0.0061
Echinococcus granulosus 7tm_1 domain containing protein 0.0016 0.0061 0.0061
Echinococcus granulosus importin subunit beta 1 0.009 0.084 0.084
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0257 0.0775
Echinococcus granulosus orexin receptor type 2 0.0016 0.0061 0.0061
Loa Loa (eye worm) helicase 0.0024 0.0142 0.0142
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Loa Loa (eye worm) hypothetical protein 0.0045 0.0369 0.0369
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0495 0.1919
Schistosoma mansoni cpg binding protein 0.0062 0.0551 0.0551
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0142 0.1623
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0014 0.004 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0425 0.0425
Onchocerca volvulus 0.0016 0.0061 0.0085
Loa Loa (eye worm) hypothetical protein 0.0048 0.0396 0.0396
Schistosoma mansoni regulator of G protein signaling 0.0049 0.0414 0.0414
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.1063 0.297
Trichomonas vaginalis chaperonin, putative 0.0025 0.0152 0.0498
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus multilocularis dna polymerase eta 0.006 0.0531 0.0531
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0553 0.0553
Trichomonas vaginalis set domain proteins, putative 0.0242 0.2448 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0061 0.0061
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.000000000048554 0.00000000050925
Loa Loa (eye worm) hypothetical protein 0.0119 0.1144 0.1144
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.094 0.284
Brugia malayi G protein-coupled receptor 0.0016 0.0061 0.0183
Entamoeba histolytica HEAT repeat domain containing protein 0.0017 0.0072 0.0398
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0197 0.1971 0.1971
Trypanosoma brucei polo-like protein kinase 0.0099 0.094 0.1446
Brugia malayi phosphofructokinase 0.0111 0.1063 0.321
Brugia malayi jmjC domain containing protein 0.0019 0.0098 0.0297
Echinococcus multilocularis serotonin receptor 0.0016 0.0061 0.0061
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0979 0.2956
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0776 0.0776
Onchocerca volvulus Neuropeptide F receptor homolog 0.0016 0.0061 0.0085
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0542 0.0542
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0543 0.2116
Brugia malayi kap beta 3 protein 0.0017 0.0072 0.0219
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0055 0.0469 0.0469
Echinococcus multilocularis Chromo domain 0.0024 0.0142 0.0142
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0014 0.004 0.004
Onchocerca volvulus Alhambra homolog 0.006 0.0528 0.2025
Schistosoma mansoni ran 0.0041 0.0329 0.0329
Brugia malayi G-protein coupled receptor 0.0016 0.0061 0.0183
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0542 0.0542
Plasmodium vivax SET domain protein, putative 0.0031 0.0221 0.2577
Plasmodium vivax transportin, putative 0.0017 0.0072 0.0795
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.004 0.004
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0014 0.004 0.0036
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0087 0.0809 0.2192
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0057 0.0079
Loa Loa (eye worm) hypothetical protein 0.009 0.084 0.084
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0163 0.0546
Echinococcus multilocularis geminin 0.0522 0.539 0.539
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0295 0.3004 0.4641
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0209 0.0734
Giardia lamblia Kinase, PLK 0.0099 0.094 1
Loa Loa (eye worm) T-complex protein 1 0.0025 0.0152 0.0152
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0061 0.0061
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0061 0.0061
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.004 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0101 0.1057
Echinococcus multilocularis G-protein coupled receptor, putative 0.0016 0.0061 0.0061
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0543 0.2116
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0061 0.0061
Plasmodium falciparum DNA repair protein REV1, putative 0.0011 0.0006 0.0073
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.002 0.0106 0.1196
Schistosoma mansoni hypothetical protein 0.0959 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.016 0.016
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0396 0.1195
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0959 1 1
Schistosoma mansoni regulator of G protein signaling 0.0049 0.0414 0.0414
Schistosoma mansoni hypothetical protein 0.0021 0.0115 0.0115
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0531 0.1603
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0094 0.1001
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0142 0.0456
Echinococcus granulosus lysine specific demethylase 5A 0.0076 0.0699 0.0699
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0209 0.2195
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0017 0.0077 0.0809
Trypanosoma brucei ISWI complex protein 0.0016 0.0058 0.008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0098 0.0098
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0025 0.0152 0.0225
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.0257 0.0257
Plasmodium vivax hypothetical protein, conserved 0.006 0.0528 0.6256
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Treponema pallidum phosphoglycerate kinase 0.0087 0.0809 0.7379
Schistosoma mansoni hypothetical protein 0.0048 0.0396 0.0396
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0057 0.0057
Brugia malayi Dopamine receptor protein 1 0.0016 0.0061 0.0183
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0087 0.0809 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0522 0.1541
Schistosoma mansoni phosphoglycerate kinase 0.0087 0.0809 0.0809
Onchocerca volvulus 0.0024 0.0142 0.0421
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0324 0.3311 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0098 0.0098
Trichomonas vaginalis hypothetical protein 0.0017 0.0072 0.017
Schistosoma mansoni GTP-binding protein alpha subunit 0.0014 0.004 0.004
Toxoplasma gondii DNA methyltransferase 2, putative 0.002 0.0106 0.111
Leishmania major cytochrome p450-like protein 0.0016 0.0057 0.0079
Echinococcus granulosus somatostatin receptor 0.0016 0.0061 0.0061
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0017 0.0072 0.0103
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0088 0.0818 0.1256
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0152 0.0498
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.3102 0.3102
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Plasmodium falciparum T-complex protein 1 subunit beta 0.0025 0.0152 0.1807
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0405 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Echinococcus multilocularis sex peptide receptor 0.0016 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0081 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Entamoeba histolytica hypothetical protein 0.0024 0.0142 0.1068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0324 0.3311 0.3311
Echinococcus multilocularis neuropeptide s receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis G protein coupled receptor 139 0.0016 0.0061 0.0061
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0026 0.0163 0.1945
Brugia malayi Regulator of G protein signaling domain containing protein 0.0049 0.0414 0.1251
Entamoeba histolytica hypothetical protein 0.0073 0.0661 0.6105
Loa Loa (eye worm) hypothetical protein 0.006 0.0531 0.0531
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.094 0.376
Brugia malayi PXA domain containing protein 0.0049 0.0414 0.1251
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0061 0.0061
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.004 0.0121
Echinococcus granulosus GTP binding nuclear protein Ran 0.0041 0.0329 0.0329
Brugia malayi TAR-binding protein 0.0062 0.0542 0.1636
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0209 0.0734
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0049 0.0414 0.0414
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0153 0.0153
Plasmodium falciparum phd finger protein, putative 0.006 0.0528 0.6283
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus multilocularis orexin receptor type 2 0.0016 0.0061 0.0061
Trypanosoma cruzi importin beta-1 subunit, putative 0.0073 0.0661 0.1014
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.094 0.376
Trichomonas vaginalis ran, putative 0.0041 0.0329 0.1233
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0142 0.0456
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0808 0.3213
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0152 0.0458
Onchocerca volvulus 0.0016 0.0061 0.0085
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Loa Loa (eye worm) importin-beta domain-containing protein 0.0017 0.0072 0.0072
Echinococcus multilocularis 0.0026 0.0163 0.0163
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.094 0.094
Schistosoma mansoni regulator of G protein signaling 0.0049 0.0414 0.0414
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0528 0.0528
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0522 0.1313
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0061 0.0061
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0024 0.0142 0.0142
Echinococcus granulosus allatostatin A receptor 0.0016 0.0061 0.0061
Schistosoma mansoni neuropeptide receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trichomonas vaginalis dullard protein, putative 0.0026 0.0163 0.0546
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Brugia malayi RNA, U transporter 1 0.0255 0.2586 0.781
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0142 0.0428
Onchocerca volvulus 0.0055 0.0469 0.1781
Trypanosoma brucei phosphoglycerate kinase 0.0087 0.0809 0.1243
Echinococcus granulosus neuropeptide s receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0543 0.0543
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0624 0.6466 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0094 0.0136
Schistosoma mansoni z-protein (S1r protein) 0.0049 0.0414 0.0414
Echinococcus granulosus g protein coupled receptor 0.0016 0.0061 0.0061
Plasmodium falciparum importin beta, putative 0.009 0.084 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0049 0.0414 0.0414
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0094 0.0094
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0087 0.0809 0.8484
Brugia malayi hypothetical protein 0.0119 0.1144 0.3456
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0039 0.0308 0.0308
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0061 0.0061
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0098 0.0098
Schistosoma mansoni hypothetical protein 0.0048 0.0396 0.0396
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0098 0.0142
Leishmania major DNA polymerase eta, putative 0.006 0.0531 0.0812
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0661 0.2605
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Loa Loa (eye worm) RNA binding protein 0.0062 0.0542 0.0542
Brugia malayi jmjC domain containing protein 0.0076 0.0699 0.2111
Echinococcus multilocularis regulator of G protein signaling 3 0.0049 0.0414 0.0414
Echinococcus granulosus peregrin 0.0063 0.0553 0.0553
Echinococcus multilocularis dro:myosuppressin receptor 0.0016 0.0061 0.0061
Brugia malayi Serotonin receptor 0.0016 0.0061 0.0183
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0094 0.026
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0119 0.1415
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0624 0.6466 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0032 0.0229 0.0346
Echinococcus granulosus Chromo domain 0.0024 0.0142 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Echinococcus granulosus DNA methyltransferase 2, putative 0.002 0.0106 0.0106
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0016 0.0061 0.0061
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0086 0.0804 0.9567
Echinococcus granulosus regulator of G protein signaling 3 0.0049 0.0414 0.0414
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0049 0.0414 0.0414
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0014 0.004 0.0121
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0257 0.0257
Brugia malayi G protein-coupled receptor F59B2.13 0.0016 0.0061 0.0183
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0528 0.5536
Onchocerca volvulus 0.0016 0.0061 0.0085
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0057 0.0057
Leishmania major hypothetical protein, conserved 0.0016 0.0058 0.008
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0041 0.0329 0.0329
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0178 0.0605
Brugia malayi sulfakinin receptor protein 0.0016 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0151 0.1481 0.1481
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0531 0.0812
Loa Loa (eye worm) hypothetical protein 0.006 0.0528 0.0528
Schistosoma mansoni ran 0.0041 0.0329 0.0329
Schistosoma mansoni hypothetical protein 0.0025 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0119 0.1144 0.1144
Echinococcus granulosus g protein coupled receptor 0.0016 0.0061 0.0061
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.004 0.004
Leishmania major hypothetical protein, conserved 0.0019 0.0098 0.0142
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.004 0.004
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0101 0.0146
Leishmania major mitochondrial DNA polymerase beta 0.0624 0.6466 1
Schistosoma mansoni regulator of G protein signaling 0.0049 0.0414 0.0414
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0328 0.0716
Loa Loa (eye worm) hypothetical protein 0.0038 0.0292 0.0292
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1063 0.1063
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0049 0.0414 0.0414
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0098 0.0098
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0098 0.0142
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0098 0.0098
Entamoeba histolytica phosphoglycerate kinase, putative 0.0087 0.0809 0.7538
Schistosoma mansoni serine/threonine protein kinase 0.0304 0.3102 0.3102
Schistosoma mansoni opsin-like receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Brugia malayi Phosphoglycerate kinase 0.0032 0.0229 0.0693
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0094 0.0284
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0142 0.0456
Echinococcus multilocularis regulator of G protein signaling 7 0.0049 0.0414 0.0414
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0209 0.0736
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis Regulator of G protein signaling 20 0.0049 0.0414 0.0414
Schistosoma mansoni zinc finger protein 0.0022 0.0121 0.0121
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0528 0.5536
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0396 0.0396
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0142 0.0142
Brugia malayi regulator of G-protein signaling egl-10 0.0049 0.0414 0.1251
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0016 0.0061 0.0085
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.0257 0.2185
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0136 0.0136
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.012 0.1432
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0329 0.0501
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0414 0.1584
Brugia malayi AF-10 protein 0.002 0.0101 0.0304
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0152 0.0458
Trichomonas vaginalis dullard protein, putative 0.0026 0.0163 0.0546
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus multilocularis transportin 1 0.0017 0.0072 0.0072
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0061 0.0061
Toxoplasma gondii t-complex protein beta subunit 0.0025 0.0152 0.1592
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0163 0.0546
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0209 0.2195
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0209 0.0736
Entamoeba histolytica hypothetical protein 0.0049 0.0414 0.3711
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0396 0.0396
Schistosoma mansoni ap endonuclease 0.0019 0.0094 0.0094
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0605
Trypanosoma brucei unspecified product 0.0024 0.0144 0.0213
Toxoplasma gondii hypothetical protein 0.0101 0.0953 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0041 0.0329 0.0995
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Toxoplasma gondii hypothetical protein 0.0086 0.0804 0.843
Onchocerca volvulus 0.0016 0.0061 0.0085
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0101 0.1057
Entamoeba histolytica G protein alpha subunit, putative 0.0014 0.004 0.0085
Loa Loa (eye worm) hypothetical protein 0.0063 0.056 0.056
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Echinococcus granulosus g protein coupled receptor 0.0016 0.0061 0.0061
Plasmodium vivax JmjC domain containing protein 0.0019 0.0098 0.1103
Echinococcus multilocularis zinc finger protein 0.0022 0.0121 0.0121
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.002 0.0106 0.0106
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0414 0.1584
Mycobacterium ulcerans hypothetical protein 0.0328 0.3355 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0142 0.1068
Loa Loa (eye worm) jmjC domain-containing protein 0.0076 0.0699 0.0699
Trypanosoma cruzi ISWI complex protein 0.0016 0.0058 0.008
Onchocerca volvulus 0.0062 0.0551 0.2121
Schistosoma mansoni hypothetical protein 0.0016 0.0058 0.0058
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Loa Loa (eye worm) melatonin receptor type 1A 0.0016 0.0061 0.0061
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0142 0.0456
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus transportin 1 0.0017 0.0072 0.0072
Brugia malayi putative neuropeptide receptor 0.0016 0.0061 0.0183
Echinococcus multilocularis regulator of G protein signaling 3 0.0049 0.0414 0.0414
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0023 0.0138 0.0138
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0061 0.0061
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0142 0.0142
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0163 0.0546
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0094 0.0136
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0543 0.1602
Echinococcus multilocularis peregrin 0.0063 0.0553 0.0553
Plasmodium vivax phosphoglycerate kinase, putative 0.0087 0.0809 0.9626
Brugia malayi hypothetical protein 0.0049 0.0414 0.1251
Brugia malayi jmjC domain containing protein 0.0019 0.0098 0.0297
Entamoeba histolytica hypothetical protein 0.0024 0.0142 0.1068
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0057 0.0057
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0405 0.0405
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0209 0.0734
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.004
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0098 0.0098
Schistosoma mansoni opsin-like receptor 0.0016 0.0061 0.0061
Plasmodium falciparum transportin 0.0017 0.0072 0.0862
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0324 0.3311 0.3311
Loa Loa (eye worm) hypothetical protein 0.0103 0.0981 0.0981
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0197 0.1971 0.1971
Echinococcus multilocularis expressed protein 0.0014 0.004 0.004
Echinococcus granulosus regulator of G protein signaling 7 0.0049 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0024 0.0142 0.0142
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.094 0.8811
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.028 0.0424
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0014 0.004 0.004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0061 0.0061
Echinococcus granulosus peptide allatostatin:somatostatin 0.0016 0.0061 0.0061
Loa Loa (eye worm) G protein alpha subunit 3 0.0014 0.004 0.004
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0098 0.0098
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0016 0.0061 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0209 0.0734
Echinococcus granulosus G protein coupled receptor 139 0.0016 0.0061 0.0061
Echinococcus multilocularis snurportin 1 0.0959 1 1
Brugia malayi Melatonin receptor type 1A 0.0016 0.0061 0.0183
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0209 0.2492
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0016 0.0061 0.0061
Echinococcus granulosus fmrfamide receptor 0.0016 0.0061 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Chlamydia trachomatis phosphoglycerate kinase 0.0087 0.0809 1
Plasmodium vivax importin-beta 2, putative 0.009 0.084 1
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0018 0.0083 0.0119
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0107 0.102 0.1569
Schistosoma mansoni kinase 0.0051 0.0429 0.0429
Echinococcus multilocularis axis inhibition protein axin 0.0049 0.0414 0.0414
Brugia malayi T-complex protein 1, beta subunit 0.0025 0.0152 0.0458
Schistosoma mansoni chromobox protein 0.0024 0.0142 0.0142
Schistosoma mansoni jumonji domain containing protein 0.0157 0.1544 0.1544
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0025 0.0152 0.0152
Echinococcus granulosus cpg binding protein 0.0066 0.0588 0.0588
Schistosoma mansoni amine GPCR 0.0016 0.0061 0.0061
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0026 0.0163 0.0546
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.002 0.0106 0.0154
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0119 0.1351
Schistosoma mansoni myosin xvIII 0.0016 0.0061 0.0061
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.004 0.004
Echinococcus multilocularis GPCR, family 2 0.0048 0.0396 0.0396
Brugia malayi chromobox protein homolog 3 0.0081 0.0743 0.2245
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0026 0.0163 0.0163
Brugia malayi ORL1-like opioid receptor 0.0016 0.0061 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.094 0.376
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0077 0.0077
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0049 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0153 0.0153
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0186 0.0186
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0061 0.0061
Leishmania major T-complex protein 1, beta subunit, putative 0.0025 0.0152 0.0225
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0041 0.0329 0.3504
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0032 0.0229 0.0346
Loa Loa (eye worm) TYRA-2 protein 0.0016 0.0061 0.0061
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0142 0.1623
Schistosoma mansoni cpg binding protein 0.0066 0.0588 0.0588
Onchocerca volvulus 0.0016 0.0061 0.0085
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0209 0.1189
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0543 0.0831
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0493 0.5174
Schistosoma mansoni jumonji/arid domain-containing protein 0.0076 0.0699 0.0699
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0808 0.3213
Loa Loa (eye worm) hypothetical protein 0.0049 0.0414 0.0414
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0776 0.0776
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus chromobox protein 2 0.0024 0.0142 0.0142
Schistosoma mansoni GTP-binding protein alpha subunit 0.0014 0.004 0.004
Schistosoma mansoni amine GPCR 0.0016 0.0061 0.0061
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0087 0.0809 0.1243
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0551 0.0551
Plasmodium falciparum phosphoglycerate kinase 0.0087 0.0809 0.9629
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0026 0.0163 0.0243
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0016 0.0061 0.0183
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0027 0.0179 0.0179
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0414 0.1584
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0026 0.0163 0.0163
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0396 0.0396
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0061 0.0061
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0061 0.0061
Onchocerca volvulus 0.0016 0.0061 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0324 0.3311 0.3311
Loa Loa (eye worm) hypothetical protein 0.0049 0.0414 0.0414
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0542 0.0542
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0209 0.0736
Loa Loa (eye worm) phosphofructokinase 0.0111 0.1063 0.1063
Schistosoma mansoni hypothetical protein 0.0522 0.539 0.539
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0522 0.0522
Echinococcus multilocularis importin subunit beta 1 0.009 0.084 0.084
Trypanosoma brucei unspecified product 0.0055 0.0472 0.0721
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0213 0.2139 0.2139
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi jmjC domain containing protein 0.0019 0.0098 0.0297
Brugia malayi putative neuropeptide receptor NPR1 0.0016 0.0061 0.0183
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0142 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.094 0.376
Echinococcus multilocularis neuropeptide FF receptor 2 0.0016 0.0061 0.0061
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0224 0.0676
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0136 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0328 0.0498
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0142 0.0456
Leishmania major GTP-binding protein, putative 0.0041 0.0329 0.0501
Schistosoma mansoni hypothetical protein 0.0048 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Loa Loa (eye worm) kap beta 3 protein 0.0017 0.0072 0.0072
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0142 0.0142
Onchocerca volvulus Huntingtin homolog 0.0119 0.1144 0.4584
Brugia malayi polk-prov protein 0.0038 0.0292 0.0883
Brugia malayi Cytochrome P450 family protein 0.0016 0.0057 0.0173
Brugia malayi Phosphoglycerate kinase 0.0087 0.0809 0.2443
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0142 0.0142
Brugia malayi Bromodomain containing protein 0.0039 0.0305 0.0923
Brugia malayi neuropeptide F receptor 0.0016 0.0061 0.0183
Brugia malayi AKH receptor 0.0016 0.0061 0.0183
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0025 0.0152 0.0152
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0025 0.0152 0.0498
Leishmania major modification methylase-like protein 0.002 0.0106 0.0154
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0094 0.0136
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0209 0.0736
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0295 0.3004 0.4641
Schistosoma mansoni opsin-like receptor 0.0016 0.0061 0.0061
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0209 0.2436
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0087 0.0809 0.0809
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0098 0.0098
Echinococcus multilocularis regulator of G protein signaling 0.0049 0.0414 0.0414
Schistosoma mansoni hypothetical protein 0.0048 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trypanosoma brucei unspecified product 0.0024 0.0144 0.0213
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0142 0.0142
Echinococcus multilocularis allatostatin A receptor 0.0016 0.0061 0.0061
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.002 0.0106 0.0722
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0215 0.0323
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0396 0.0396
Echinococcus multilocularis serotonin receptor 0.0016 0.0061 0.0061
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0522 0.0522
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0098 0.0098
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.004 0.004
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0415 0.1589
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.1481 0.4473
Schistosoma mansoni axis inhibition protein axin 0.0049 0.0414 0.0414
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0014 0.004 0.004
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0257 0.0499
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0026 0.0163 0.1886
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.094 0.376
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Onchocerca volvulus 0.0016 0.0061 0.0085
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0098 0.0098
Brugia malayi G-protein alpha subunit 0.0014 0.004 0.0121
Brugia malayi G-protein coupled receptor 0.0016 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0061 0.0061
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0032 0.0229 0.0346
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Schistosoma mansoni adenoreceptor 0.0016 0.0061 0.0061
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0072 0.076
Brugia malayi Tachykinin-like peptides receptor 99D 0.0016 0.0061 0.0183
Schistosoma mansoni hypothetical protein 0.006 0.0528 0.0528
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0041 0.0329 0.3877
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0173 0.0585
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0014 0.004 0.0121
Echinococcus granulosus translational activator gcn1 0.0017 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0522 0.1541
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0495 0.1919
Entamoeba histolytica hypothetical protein 0.0049 0.0414 0.3711
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0041 0.0329 0.3922
Brugia malayi PHD-finger family protein 0.006 0.0528 0.1594
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.094 0.1446
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0535 0.0535
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.1063 0.1063
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0221 0.0221
Toxoplasma gondii HEAT repeat-containing protein 0.009 0.084 0.8811
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0049 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0024 0.0142 0.0142
Echinococcus granulosus neuropeptide receptor 0.0016 0.0061 0.0061
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0014 0.004 0.0121
Leishmania major DNA polymerase kappa, putative 0.0041 0.0328 0.0498
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0016 0.0061 0.0061
Echinococcus granulosus dna polymerase kappa 0.0062 0.0543 0.0543
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0014 0.004 0.004
Leishmania major hypothetical protein, conserved 0.0026 0.0163 0.0243
Echinococcus granulosus beta-adrenergic receptor kinase 0.0304 0.3102 0.3102
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.0661 0.0661
Onchocerca volvulus 0.0016 0.0061 0.0085
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus axis inhibition protein axin 0.0049 0.0414 0.0414
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0014 0.004 0.0036
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0142 0.1485
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0083 0.0083
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0522 0.0522
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0014 0.004 0.004
Onchocerca volvulus 0.0242 0.2448 1
Entamoeba histolytica hypothetical protein 0.0024 0.0142 0.1068
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.002 0.0106 0.111
Schistosoma mansoni chromobox protein 0.0144 0.141 0.141
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.004 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Schistosoma mansoni growth hormone secretagogue receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.1063 0.1063
Brugia malayi RNA binding protein 0.0062 0.0542 0.1636
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0415 0.1589
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.1063 1
Echinococcus multilocularis neuropeptide receptor A26 0.0016 0.0061 0.0061
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.004 0.004
Echinococcus multilocularis translational activator gcn1 0.0017 0.0072 0.0072
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.004 0.0036
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0016 0.0061 0.0183
Onchocerca volvulus 0.0016 0.0061 0.0085
Brugia malayi Dopamine receptor 0.0016 0.0061 0.0183
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0041 0.0329 0.0501
Echinococcus granulosus serotonin receptor 0.0016 0.0061 0.0061
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0396 0.1195
Echinococcus granulosus expressed protein 0.0014 0.004 0.004
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0025 0.0152 0.0225
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0014 0.004 0.0121
Brugia malayi Bromodomain containing protein 0.0078 0.0717 0.2166
Onchocerca volvulus 0.0016 0.0061 0.0085
Brugia malayi RE15519p 0.0016 0.0061 0.0183
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0163 0.0243
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0014 0.004 0.004
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0101 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.0257 0.0257
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.094 0.376
Brugia malayi Pre-SET motif family protein 0.0213 0.2139 0.6461
Brugia malayi Dopamine receptor protein 2 0.0016 0.0061 0.0183
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0025 0.0152 0.1167
Loa Loa (eye worm) hypothetical protein 0.0072 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0142 0.0428
Brugia malayi regulator of G-protein signaling rgs-7 0.0049 0.0414 0.1251
Giardia lamblia TCP-1 chaperonin subunit beta 0.0025 0.0152 0.1614
Echinococcus granulosus chromobox protein 1 0.0144 0.141 0.141
Onchocerca volvulus 0.0024 0.0142 0.0421
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0077 0.0077
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0016 0.0061 0.0061
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0031 0.0039
Echinococcus granulosus tachykinin peptides receptor 99D 0.0016 0.0061 0.0061
Onchocerca volvulus 0.0016 0.0061 0.0085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0061 0.0061
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0026 0.0163 0.1714
Onchocerca volvulus Huntingtin homolog 0.0119 0.1144 0.4584
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0016 0.0061 0.0061
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.002 0.0106 0.126
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1063 0.4268
Echinococcus granulosus zinc finger protein 0.0022 0.0121 0.0121
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Toxoplasma gondii exonuclease III APE 0.0019 0.0094 0.0987
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0098 0.0142
Leishmania major DNA polymerase eta, putative 0.0037 0.028 0.0424
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Echinococcus granulosus CTD small phosphatase protein like 0.0026 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0072 0.076
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0661 0.2605
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0061 0.0061
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0088 0.0818 0.1256
Schistosoma mansoni phosphoglycerate kinase 0.0087 0.0809 0.0809
Brugia malayi Regulator of G protein signaling domain containing protein 0.0049 0.0414 0.1251
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0142 0.0142
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0221 0.2318
Brugia malayi A-kinase anchor protein 10, precursor 0.0049 0.0414 0.1251
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0061
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0164 0.0164
Echinococcus multilocularis disco interacting protein 2 0.0039 0.0308 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0743 0.2946
Echinococcus granulosus neuropeptide receptor 0.0016 0.0061 0.0061
Echinococcus granulosus dro:myosuppressin receptor 0.0016 0.0061 0.0061
Brugia malayi PHD-finger family protein 0.0027 0.0178 0.0539
Echinococcus granulosus bloom syndrome protein 0.0025 0.0152 0.0152
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0061 0.0061
Echinococcus granulosus phosphoglycerate kinase 1 0.0087 0.0809 0.0809
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0016 0.0061 0.0061
Onchocerca volvulus 0.0063 0.056 0.2157
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0031 0.0039
Echinococcus multilocularis DNA methyltransferase 2, putative 0.002 0.0106 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0221 0.0221
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0016 0.0061 0.0061
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0026 0.0163 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0414 0.1584
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0061 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1063 1
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0209 0.2436
Trichomonas vaginalis chromobox protein, putative 0.0144 0.141 0.5702
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0142 0.1623
Echinococcus granulosus Chromobox protein 3 0.0024 0.0142 0.0142
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0292 0.0443
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0522 0.539 0.539
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.1063 0.3155
Echinococcus granulosus phd:f box containing protein 0.0019 0.0098 0.0098
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0542 0.0542
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1063 1
Brugia malayi hypothetical protein 0.0024 0.0142 0.0428
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.1481 0.1481
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus 7TM GPCR rhodopsin 0.0016 0.0061 0.0061
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0016 0.0061 0.0183
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0027 0.0179 0.0179
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.028 0.2939
Echinococcus multilocularis importin 5 0.0017 0.0072 0.0072
Trypanosoma brucei phosphoglycerate kinase 0.0087 0.0809 0.1243
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0152 0.0498
Brugia malayi larval opioid receptor 0.0016 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0094 0.112
Schistosoma mansoni neuropeptide f receptor 76f 0.0016 0.0061 0.0061
Brugia malayi 6-phosphofructokinase 0.0111 0.1063 0.321
Echinococcus granulosus alpha 1A adrenergic receptor 0.0016 0.0061 0.0061
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1063 0.1636
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0542 0.0542
Loa Loa (eye worm) PXA domain-containing protein 0.0049 0.0414 0.0414
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0098 0.0098
Echinococcus granulosus axis inhibition protein axin 0.0049 0.0414 0.0414
Schistosoma mansoni neuropeptide receptor 0.0016 0.0061 0.0061
Schistosoma mansoni importin-beta 2 0.0017 0.0072 0.0072
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0531 0.0812
Loa Loa (eye worm) RecQ helicase 0.0025 0.0152 0.0152
Echinococcus multilocularis expressed protein 0.0419 0.431 0.431
Schistosoma mansoni biogenic amine receptor 0.0016 0.0061 0.0061
Brugia malayi Disco-interacting protein 2 homolog 0.0039 0.0308 0.093
Loa Loa (eye worm) hypothetical protein 0.0123 0.1193 0.1193
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0088 0.0818 0.1256
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0542 0.1636
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0152 0.0152
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Mycobacterium ulcerans phosphoglycerate kinase 0.0087 0.0809 0.2397
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1063 0.4268
Echinococcus multilocularis chromobox protein 1 0.0144 0.141 0.141
Schistosoma mansoni hypothetical protein 0.0103 0.0979 0.0979
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0522 0.0522
Schistosoma mansoni jumonji/arid domain-containing protein 0.0076 0.0699 0.0699
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.1481 0.4473
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0209 0.0734
Brugia malayi CXXC zinc finger family protein 0.0062 0.0551 0.1664
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0025 0.0152 0.1746
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.094 0.094
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0295 0.3004 0.4641
Schistosoma mansoni axis inhibition protein axin 0.0049 0.0414 0.0414
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0014 0.004 0.004
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0209 0.0736
Echinococcus granulosus tm gpcr rhodopsin 0.0622 0.6452 0.6452
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0142 0.1685
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0032 0.0229 0.0346
Echinococcus multilocularis chromobox protein 1 0.0144 0.141 0.141
Onchocerca volvulus 0.0016 0.0061 0.0085
Schistosoma mansoni biogenic amine receptor 0.0016 0.0061 0.0061
Giardia lamblia Phosphoglycerate kinase 0.0087 0.0809 0.8604
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0142 0.1685
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0094 0.1055
Leishmania major importin beta-1 subunit, putative 0.0073 0.0661 0.1014
Schistosoma mansoni hypothetical protein 0.002 0.0101 0.0101
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.004 0.0121
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0142 0.1485
Brugia malayi Serotonin receptor 0.0016 0.0061 0.0183
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0542 0.0542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0098 0.1169
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0528 0.0528
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0324 0.3311 0.3311
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0142 0.1685
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0142 0.0456
Loa Loa (eye worm) heterochromatin protein 1 0.0144 0.141 0.141
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0142 0.0142
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0622 0.6452 0.6452
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0152 0.0152
Giardia lamblia DINP protein human, muc B family 0.0041 0.0328 0.3486
Schistosoma mansoni hypothetical protein 0.0024 0.0142 0.0142
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0522 0.5477
Entamoeba histolytica hypothetical protein 0.0049 0.0414 0.3711
Leishmania major phosphoglycerate kinase C, glycosomal 0.0087 0.0809 0.1243
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.094 0.1446
Brugia malayi hypothetical protein 0.0049 0.0414 0.1251
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1063 1
Brugia malayi 6-phosphofructokinase 0.0111 0.1063 0.321
Schistosoma mansoni zinc finger protein 0.0016 0.0058 0.0058
Brugia malayi GnHR receptor homolog 0.0016 0.0061 0.0183
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0743 0.2946
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0098 0.0098
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0142 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0087 0.0809 0.8484
Echinococcus granulosus regulator of G protein signaling 7 0.0049 0.0414 0.0414
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0098 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.0328 0.3355 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0016 0.0061 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0543 0.1602
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0209 0.2492
Echinococcus multilocularis cpg binding protein 0.0066 0.0588 0.0588
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0049 0.0414 0.0414
Echinococcus multilocularis chromobox protein 2 0.0024 0.0142 0.0142
Echinococcus granulosus chromobox protein 1 0.0144 0.141 0.141
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.004 0.004
Echinococcus multilocularis somatostatin receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0061 0.0061
Brugia malayi Cytochrome P450 family protein 0.0026 0.0164 0.0496
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.094 0.094
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0203 0.0203
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0031 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0209 0.0734
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0094 0.0263
Loa Loa (eye worm) hypothetical protein 0.0024 0.0142 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0542 0.0542
Onchocerca volvulus 0.0016 0.0061 0.0085
Loa Loa (eye worm) hypothetical protein 0.0103 0.0979 0.0979
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0405 0.0405
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis beta adrenergic receptor kinase 0.0304 0.3102 0.3102
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0292 0.0443
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0032 0.0229 0.0346
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0014 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0522 0.0799
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0098 0.0098
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0057 0.0153
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0014 0.004 0.004
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0026 0.0163 0.1886
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Brugia malayi follicle stimulating hormone receptor 0.0016 0.0061 0.0183
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0324 0.3311 0.3311
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.084 0.1291
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.028 0.028
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0016 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0088 0.0818 0.1256
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0061 0.0061
Echinococcus granulosus neuropeptide FF receptor 2 0.0016 0.0061 0.0061
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0087 0.0808 0.3188
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0014 0.004 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Echinococcus granulosus hypothetical protein 0.0016 0.0061 0.0061
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0014 0.004 0.004
Schistosoma mansoni DNA polymerase eta 0.006 0.0531 0.0531
Echinococcus granulosus GPCR family 2 0.0048 0.0396 0.0396
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0041 0.0329 0.0329
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0153 0.0153
Schistosoma mansoni DNA polymerase IV / kappa 0.0011 0.0006 0.0006
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0041 0.0329 0.3456
Trichomonas vaginalis dullard protein, putative 0.0026 0.0163 0.0546
Brugia malayi jmjC domain containing protein 0.0019 0.0098 0.0297
Giardia lamblia DNA damage repair protein 0.0011 0.0006 0.0066
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0061 0.0061
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0026 0.0163 0.0494
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0057 0.0079
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0094 0.0136
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0066 0.0692
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0014 0.004 0.0036
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0016 0.0061 0.0061
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0098 0.0098
Echinococcus granulosus tar DNA binding protein 0.0062 0.0542 0.0542
Brugia malayi Importin beta-1 subunit 0.009 0.084 0.2537
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0553 0.0553
Schistosoma mansoni chromobox protein 0.0144 0.141 0.141
Schistosoma mansoni regulator of G protein signaling 0.0049 0.0414 0.0414
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0016 0.0061 0.0061
Schistosoma mansoni amine GPCR 0.0016 0.0061 0.0061
Trichomonas vaginalis chromobox protein, putative 0.0144 0.141 0.5702
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0179 0.0179
Schistosoma mansoni ap endonuclease 0.0019 0.0094 0.0094
Trypanosoma brucei phosphoglycerate kinase, putative 0.0032 0.0229 0.0346
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0061 0.0061
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0014 0.004 0.004
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0209 0.1725
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1063 0.1063
Trypanosoma cruzi ISWI complex protein 0.0016 0.0058 0.008
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0304 0.3102 0.3102
Echinococcus granulosus sex peptide receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0061 0.0061
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.1063 0.1636
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Onchocerca volvulus 0.0016 0.0061 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0324 0.3311 0.3311
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0077 0.0077
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0209 0.0734
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0061 0.0061
Schistosoma mansoni neuropeptide receptor 0.0016 0.0061 0.0061
Echinococcus granulosus expressed protein 0.0419 0.431 0.431
Schistosoma mansoni importin beta-1 0.009 0.084 0.084
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0542 0.0542
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0098 0.0098
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0255 0.2581 0.2581
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.005 0.0425 0.1283
Schistosoma mansoni cpg binding protein 0.0066 0.0588 0.0588
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.094 0.3737
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0324 0.3311 0.3311
Loa Loa (eye worm) hypothetical protein 0.0049 0.0414 0.0414
Brugia malayi CHD4 protein 0.0027 0.0179 0.0541
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.004 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0215 0.0323
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0528 0.0528
Leishmania major phosphoglycerate kinase B, cytosolic 0.0087 0.0809 0.1243
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0057 0.0079
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi hypothetical protein 0.0016 0.0061 0.0183
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0049 0.0414 0.1584
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0016 0.0061 0.0061
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0142 0.1068
Loa Loa (eye worm) hypothetical protein 0.0024 0.0142 0.0142
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0624 0.6466 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0077 0.0077
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.0049 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0094 0.0609
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0414 0.1584
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0152 0.0152
Schistosoma mansoni bromodomain containing protein 0.0066 0.0591 0.0591
Loa Loa (eye worm) CHromoDomain protein family member 0.0027 0.0179 0.0179
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.1203 0.1203
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0209 0.0736
Echinococcus multilocularis phosphoglycerate kinase 1 0.0087 0.0809 0.0809
Schistosoma mansoni chromobox protein 0.0024 0.0142 0.0142
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0081 0.0743 0.292
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0472 0.0721
Echinococcus granulosus G protein coupled receptor kinase 1 0.0255 0.2581 0.2581
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0414 0.1584
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0026 0.0163 0.128
Schistosoma mansoni hypothetical protein 0.0016 0.0061 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0098 0.103
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0209 0.0736
Schistosoma mansoni amine GPCR 0.0016 0.0061 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1063 0.4268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Giardia lamblia PHD finger protein 15 0.006 0.0528 0.5614
Schistosoma mansoni amine GPCR 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0098 0.0098
Onchocerca volvulus 0.0016 0.0061 0.0085
Brugia malayi hypothetical protein 0.0014 0.004 0.0121
Brugia malayi Bromodomain containing protein 0.0063 0.0553 0.1671
Loa Loa (eye worm) hypothetical protein 0.0026 0.0163 0.0163
Brugia malayi PXA domain containing protein 0.0049 0.0414 0.1251
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0014 0.004 0.0036
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0016 0.0061 0.0061
Schistosoma mansoni histamine h1 receptor 0.0016 0.0061 0.0061
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.084 0.1291
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0006 0.0065
Echinococcus granulosus geminin 0.0522 0.539 0.539
Loa Loa (eye worm) hypothetical protein 0.0048 0.0405 0.0405
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0061 0.0061
Schistosoma mansoni alpha-1 adrenergic receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.094 0.094
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0016 0.0061 0.0061
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.1063 1
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0014 0.004 0.004
Onchocerca volvulus 0.0016 0.0061 0.0085
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0209 0.2195
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0014 0.004 0.004
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0209 0.2226
Brugia malayi SET domain containing protein 0.0025 0.016 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0142 0.0456
Onchocerca volvulus 0.0039 0.0308 0.1111
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0061 0.0061
Trichomonas vaginalis importin beta-1, putative 0.0073 0.0661 0.2605
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0329 0.0501
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.0257 0.0257
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.028 0.028
Echinococcus granulosus Regulator of G protein signaling 20 0.0049 0.0414 0.0414
Echinococcus granulosus importin 5 0.0017 0.0072 0.0072
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0087 0.0809 0.3217
Loa Loa (eye worm) hypothetical protein 0.0042 0.0332 0.0332
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0522 0.1541
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0209 0.0734
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.004
Trypanosoma brucei phosphoglycerate kinase 0.0032 0.0229 0.0346
Entamoeba histolytica Ran family GTPase 0.0041 0.0329 0.289
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0324 0.3311 0.3311
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0016 0.0061 0.0183
Loa Loa (eye worm) hypothetical protein 0.0014 0.004 0.004
Brugia malayi PHD-finger family protein 0.0023 0.0138 0.0418
Brugia malayi Heterochromatin protein 1 0.0144 0.141 0.4258
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1063 0.4268
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi Cytochrome P450 family protein 0.0016 0.0057 0.0173
Trichomonas vaginalis hypothetical protein 0.0024 0.0142 0.0456
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0032 0.0229 0.0346
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0061 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0016 0.0061 0.0061
Echinococcus granulosus g-protein coupled receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0039 0.0308 0.0308
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0115 0.0115
Brugia malayi neuropeptide F receptor 0.0016 0.0061 0.0183
Leishmania major hypothetical protein, conserved 0.0017 0.0072 0.0103
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0087 0.0809 0.3217
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0014 0.004 0.0121
Loa Loa (eye worm) hypothetical protein 0.0049 0.0414 0.0414
Brugia malayi Protein cec-1. 0.0024 0.0142 0.0428
Echinococcus granulosus dna polymerase eta 0.006 0.0531 0.0531
Brugia malayi M-phase phosphoprotein, mpp8 0.0024 0.0142 0.0428
Schistosoma mansoni neuropeptide receptor 0.0016 0.0061 0.0061
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.0257 0.0257
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.094 0.1446
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0094 0.026
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0801 0.8337 0.8337
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0016 0.0061 0.0061
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0328 0.0498
Schistosoma mansoni biogenic amine receptor 0.0016 0.0061 0.0061
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0142 0.0428
Onchocerca volvulus 0.0016 0.0061 0.0085
Echinococcus multilocularis axis inhibition protein axin 0.0049 0.0414 0.0414
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0097 0.0097
Echinococcus granulosus regulator of G protein signaling 3 0.0049 0.0414 0.0414
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0061 0.0061
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0142 0.0456
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.005 0.0425 0.0425
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0026 0.0163 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Brugia malayi Pre-SET motif family protein 0.0031 0.0221 0.0668
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1063 0.1636
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0215 0.0323
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0068 0.0742
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0543 0.0831
Echinococcus granulosus disco interacting protein 2 0.0039 0.0308 0.0308
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0049 0.0414 0.0414
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0061 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.094 0.376
Loa Loa (eye worm) RGS-3 protein 0.0049 0.0414 0.0414
Brugia malayi jmjC domain containing protein 0.0197 0.1971 0.5954
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0094 0.0094
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0087 0.0809 0.1243
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0025 0.0152 0.0152
Echinococcus granulosus neuropeptide receptor A26 0.0016 0.0061 0.0061
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0014 0.004 0.004
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0142 0.1485
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0061 0.0061
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0543 0.0831
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0098 0.103
Echinococcus multilocularis g-protein coupled receptor 0.0016 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0061 0.0061

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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