Detailed information for compound 705356

Basic information

Technical information
  • TDR Targets ID: 705356
  • Name: 5-fluoro-N-[2-(4-fluorophenyl)sulfonyl-2-fura n-2-ylethyl]-2-methoxybenzenesulfonamide
  • MW: 457.468 | Formula: C19H17F2NO6S2
  • H donors: 1 H acceptors: 4 LogP: 2.62 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1S(=O)(=O)NCC(S(=O)(=O)c1ccc(cc1)F)c1ccco1)F
  • InChi: 1S/C19H17F2NO6S2/c1-27-16-9-6-14(21)11-18(16)30(25,26)22-12-19(17-3-2-10-28-17)29(23,24)15-7-4-13(20)5-8-15/h2-11,19,22H,12H2,1H3
  • InChiKey: LQGKFCWYHSAMMW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-fluoro-N-[2-(4-fluorophenyl)sulfonyl-2-(2-furyl)ethyl]-2-methoxy-benzenesulfonamide
  • 5-fluoro-N-[2-(4-fluorophenyl)sulfonyl-2-(2-furyl)ethyl]-2-methoxybenzenesulfonamide
  • 5-fluoro-N-[2-(4-fluorophenyl)sulfonyl-2-furan-2-yl-ethyl]-2-methoxy-benzenesulfonamide
  • G857-1555
  • NCGC00137352-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0043 0.025 0.1085
Schistosoma mansoni caspase-7 (C14 family) 0.0063 0.0394 0.1698
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0268 0.1163
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0009 0.0003 0.0015
Trypanosoma brucei THT1 - hexose transporter, putative 0.0101 0.067 0.8302
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0207 0.2535
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.017 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0268 0.1163
Brugia malayi Cell death protein 3 precursor 0.0063 0.0394 0.1707
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0046 0.0268 0.1468
Echinococcus multilocularis caspase 0.0019 0.0073 0.0315
Toxoplasma gondii sugar transporter ST2 0.0046 0.0268 0.0404
Echinococcus granulosus lamin dm0 0.0033 0.0171 0.0742
Leishmania major hypothetical protein, conserved 0.0046 0.0268 0.3322
Brugia malayi lysyl-tRNA synthetase 0.0073 0.0464 0.2012
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.067 0.2906
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0009 0.0003 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0528 0.3769 0.568
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0009 0.0003 0.0015
Echinococcus granulosus glutamate synthase 0.0009 0.0003 0.0015
Brugia malayi Sugar transporter family protein 0.0327 0.2305 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0098 0.0646 0.8004
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0015 0.0063
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0071 0.0845
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0073 0.0073
Brugia malayi intermediate filament protein 0.0033 0.0171 0.0742
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0665 0.1002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0193 0.2362
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0049 0.0212
Mycobacterium ulcerans beta-lactamase 0.0038 0.0207 0.2535
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0018 0.0068 0.0103
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0193 0.2394
Leishmania major asparaginyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Plasmodium vivax thioredoxin reductase, putative 0.0103 0.0681 0.0681
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.0006 0.0026
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.017 0.017
Plasmodium vivax aspartate--tRNA ligase, putative 0.0011 0.0015 0.0015
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Plasmodium falciparum asparagine--tRNA ligase 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0723 0.3135
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0003 0.0015
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0193 0.0838
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0049 0.0212
Trypanosoma cruzi hexose transporter, putative 0.0046 0.0268 0.3322
Echinococcus granulosus histidyl tRNA synthetase 0.0011 0.0015 0.0065
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0071 0.1103
Schistosoma mansoni glutamate synthase 0.0009 0.0003 0.0015
Brugia malayi RNA binding protein 0.0076 0.049 0.2125
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0184 0.0799
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0046 0.0268 0.1468
Loa Loa (eye worm) hypothetical protein 0.0109 0.0723 0.3135
Brugia malayi Aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0306 0.1328
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.017 0.017
Loa Loa (eye worm) programmed cell death 8 0.0009 0.0003 0.0015
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0665 0.0665
Plasmodium falciparum metacaspase-like protein 0.0019 0.0073 0.0073
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0009 0.0003 0.0042
Echinococcus multilocularis glutamate synthase 0.0009 0.0003 0.0015
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.017 0.017
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0062 0.0384 0.2104
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.012 0.0807 0.442
Plasmodium falciparum mitogen-activated protein kinase 2 0.0528 0.3769 0.3769
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Leishmania major hypothetical protein, conserved 0.0016 0.0053 0.0652
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0018 0.0068 0.0296
Plasmodium falciparum metacaspase 1 0.0019 0.0073 0.0073
Schistosoma mansoni cpg binding protein 0.003 0.0155 0.0669
Plasmodium vivax asparagine--tRNA ligase, putative 0.0011 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0723 0.3135
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.0006 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0053 0.0652
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0207 0.0898
Schistosoma mansoni sugar transporter 0.0046 0.0268 0.1157
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0193 0.2394
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0184 0.0799
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0207 0.2566
Mycobacterium tuberculosis Probable dehydrogenase 0.0234 0.1636 0.896
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0073 0.09
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0011 0.0015 0.0063
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0807 0.3501
Schistosoma mansoni glutamate synthase 0.0009 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0098 0.0646 0.2802
Treponema pallidum glycyl-tRNA synthetase 0.0011 0.0015 0.0143
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0207 0.0898
Brugia malayi Sugar transporter family protein 0.0046 0.0268 0.1163
Echinococcus multilocularis calcium dependent protein kinase 0.0094 0.0616 0.2671
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0009 0.0003 0.0015
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0234 0.1636 0.896
Echinococcus granulosus synaptic vesicle 2 protein 0.0046 0.0268 0.1163
Schistosoma mansoni ap endonuclease 0.0019 0.0071 0.0308
Echinococcus granulosus Threonyl tRNA synthetase C 0.0018 0.0068 0.0296
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0327 0.2305 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0898
Brugia malayi MAP kinase sur-1 0.0061 0.0377 0.1635
Onchocerca volvulus 0.0046 0.0268 0.6813
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0193 0.1058
Plasmodium vivax CDK-related protein kinase 6, putative 0.1387 1 1
Schistosoma mansoni tar DNA-binding protein 0.0076 0.049 0.2114
Echinococcus granulosus smad 0.001 0.0006 0.0026
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.025 0.1085
Echinococcus multilocularis caspase 8 0.0019 0.0073 0.0315
Echinococcus granulosus General substrate transporter 0.0281 0.1972 0.8554
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0073 0.0464 0.5748
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0009 0.0003 0.0015
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trypanosoma brucei protein kinase, putative 0.0061 0.0377 0.4671
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0193 0.0291
Onchocerca volvulus 0.0046 0.0268 0.6813
Trypanosoma brucei sugar transporter, putative 0.0046 0.0268 0.3322
Echinococcus granulosus glycyl tRNA synthetase 0.0018 0.0068 0.0296
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0375 0.463
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0019 0.0073 0.0315
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0009 0.0003 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0664 0.2881
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0009 0.0003 0.0042
Treponema pallidum NADH oxidase 0.0036 0.0193 0.2362
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0009 0.0003 0.0005
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0375 0.1629
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0375 0.4653
Onchocerca volvulus 0.0038 0.0207 0.5263
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0009 0.0003 0.0042
Loa Loa (eye worm) hypothetical protein 0.0098 0.0646 0.2802
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Giardia lamblia Thioredoxin reductase 0.0009 0.0003 0.0052
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0207 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0053 0.0228
Leishmania major glucose transporter/membrane transporter D2, putative 0.0101 0.067 0.8302
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0193 0.2394
Echinococcus multilocularis thioredoxin glutathione reductase 0.0103 0.0685 0.2971
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0011 0.0015 0.0063
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0061 0.0266
Plasmodium vivax asparagine--tRNA ligase, putative 0.0011 0.0015 0.0015
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Echinococcus multilocularis solute carrier family 22 0.0046 0.0268 0.1163
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0073 0.0315
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0327 0.2305 1
Schistosoma mansoni tar DNA-binding protein 0.0076 0.049 0.2114
Schistosoma mansoni hypothetical protein 0.0034 0.0184 0.0794
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0377 0.1635
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.017 0.017
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0011 0.0015 0.0065
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0061 0.0377 0.4671
Trichomonas vaginalis sugar transporter, putative 0.0101 0.067 0.2906
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0009 0.0003 0.0018
Treponema pallidum aspartyl-tRNA synthetase 0.0011 0.0015 0.0139
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0018 0.0068 0.2447
Toxoplasma gondii aspartate-tRNA ligase 0.0011 0.0015 0.0022
Brugia malayi glutathione reductase 0.0103 0.0681 0.2952
Trypanosoma cruzi metacaspase, putative 0.0019 0.0073 0.09
Giardia lamblia Glutamate synthase 0.0009 0.0003 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0268 0.1163
Trypanosoma brucei Metacaspase-4 0.0019 0.0073 0.09
Brugia malayi TAR-binding protein 0.0076 0.049 0.2125
Echinococcus granulosus solute carrier family 22 0.0046 0.0268 0.1163
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0018 0.0068 0.0296
Loa Loa (eye worm) hypothetical protein 0.0074 0.0473 0.2054
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0073 0.0315
Echinococcus granulosus calcium dependent protein kinase 0.0094 0.0616 0.2671
Brugia malayi hypothetical protein 0.0046 0.0268 0.1163
Giardia lamblia Threonyl-tRNA synthetase 0.0018 0.0068 0.1055
Toxoplasma gondii anticodon binding domain-containing protein 0.0011 0.0015 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0375 0.463
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0073 0.0109
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0207 0.0898
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0898
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0009 0.0003 0.0015
Onchocerca volvulus 0.0009 0.0003 0.0086
Onchocerca volvulus 0.0038 0.0207 0.5263
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0009 0.0003 0.0015
Leishmania major hypothetical protein, conserved 0.0009 0.0003 0.0042
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0807 1
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0018 0.0068 0.0844
Schistosoma mansoni tar DNA-binding protein 0.0076 0.049 0.2114
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0073 0.0464 0.573
Leishmania major protein kinase, putative 0.0101 0.0664 0.8231
Trypanosoma brucei hypothetical protein, conserved 0.0009 0.0003 0.0042
Entamoeba histolytica hypothetical protein 0.0073 0.0464 0.5748
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0073 0.0109
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0268 0.1163
Leishmania major aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0377 0.1627
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Plasmodium vivax histidine--tRNA ligase, putative 0.0011 0.0015 0.0015
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0665 0.0665
Mycobacterium ulcerans hypothetical protein 0.0038 0.0207 0.2535
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.025 0.1079
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0018 0.0068 0.0373
Plasmodium vivax proline--tRNA ligase, putative 0.0114 0.0764 0.0764
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0019 0.0073 0.0315
Schistosoma mansoni tar DNA-binding protein 0.0076 0.049 0.2114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Echinococcus multilocularis mitogen activated protein kinase 3 0.0061 0.0377 0.1635
Echinococcus multilocularis solute carrier family 22 0.0046 0.0268 0.1163
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0011 0.0015 0.0143
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0061 0.0377 0.4671
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0268 0.1163
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0234 0.1636 0.896
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0193 0.7171
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0073 0.0313
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0207 0.0894
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0473 0.2054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0296
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0046 0.0268 0.3294
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0327 0.2305 1
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0011 0.0015 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0125 0.0541
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0306 0.1328
Entamoeba histolytica hypothetical protein 0.0043 0.025 0.3098
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0268 0.1163
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0009 0.0003 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0207 0.0894
Plasmodium falciparum glutathione reductase 0.0036 0.0193 0.0193
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0009 0.0003 0.0015
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0009 0.0003 0.0015
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0009 0.0003 0.0042
Loa Loa (eye worm) hypothetical protein 0.0073 0.0464 0.2012
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Schistosoma mansoni glucose transport protein 0.0327 0.2305 0.9947
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0327 0.2305 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0114 0.0764 0.9465
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0981 0.4255
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0664 0.2881
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0375 0.162
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0071 0.039
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0898
Schistosoma mansoni protein kinase 0.0101 0.0664 0.2866
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0071 0.0309
Leishmania major histidyl-tRNA synthetase, putative 0.0011 0.0015 0.0184
Echinococcus multilocularis synaptic vesicle 2 protein 0.0046 0.0268 0.1163
Leishmania major glycyl tRNA synthetase, putative 0.0011 0.0015 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0268 0.1163
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.017 0.2079
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0327 0.2305 1
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0114 0.0764 0.9465
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.025 0.1085
Schistosoma mansoni hypothetical protein 0.0044 0.0256 0.1103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0306 0.1321
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.017 0.0739
Loa Loa (eye worm) hypothetical protein 0.0101 0.0664 0.2881
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.012 0.0807 0.442
Trypanosoma cruzi sugar transporter, putative 0.0046 0.0268 0.3322
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.017 0.0257
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0009 0.0003 0.0042
Schistosoma mansoni glutamate synthase 0.0009 0.0003 0.0015
Entamoeba histolytica hypothetical protein 0.0043 0.025 0.3098
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0664 0.2881
Plasmodium falciparum hexose transporter 0.0327 0.2305 0.2305
Echinococcus granulosus solute carrier family 22 0.0046 0.0268 0.1163
Brugia malayi major facilitator superfamily protein 0.0046 0.0268 0.1163
Plasmodium vivax threonine--tRNA ligase, putative 0.0018 0.0068 0.0068
Brugia malayi hypothetical protein 0.0046 0.0268 0.1163
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Schistosoma mansoni cpg binding protein 0.003 0.0155 0.0669
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0664 0.2881
Mycobacterium ulcerans sugar transporter 0.0046 0.0268 0.3294
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0327 0.2305 1
Trichomonas vaginalis conserved hypothetical protein 0.0327 0.2305 1
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0053 0.0652
Schistosoma mansoni glucose transporter 0.0046 0.0268 0.1157
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0009 0.0003 0.0003
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0665 0.0665
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.017 0.2112
Trichomonas vaginalis glutamate synthase, putative 0.0009 0.0003 0.0015
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0009 0.0003 0.0015
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0009 0.0003 0.0042
Leishmania major metacaspase, putative 0.0019 0.0073 0.09
Onchocerca volvulus 0.0046 0.0268 0.6813
Schistosoma mansoni tar DNA-binding protein 0.0076 0.049 0.2114
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0898
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0171 0.0742
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0009 0.0003 0.0003
Trypanosoma cruzi hexose transporter, putative 0.0101 0.067 0.8302
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0103 0.0681 0.3727
Plasmodium falciparum threonine--tRNA ligase 0.0018 0.0068 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0073 0.0315
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.017 0.0739
Trypanosoma cruzi hexose transporter, putative 0.0101 0.067 0.8302
Trichomonas vaginalis esterase, putative 0.0038 0.0207 0.0898
Brugia malayi Thioredoxin reductase 0.0103 0.0681 0.2952
Brugia malayi major facilitator superfamily protein 0.0046 0.0268 0.1163
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.017 0.3627
Schistosoma mansoni hypothetical protein 0.0043 0.025 0.1079
Trypanosoma brucei metacaspase 0.0019 0.0073 0.09
Schistosoma mansoni sugar transporter 0.0046 0.0268 0.1157
Echinococcus granulosus tar DNA binding protein 0.0076 0.049 0.2125
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0193 0.0834
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0062 0.0384 0.2104
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0009 0.0003 0.0015
Onchocerca volvulus 0.0046 0.0268 0.6813
Schistosoma mansoni smad 0.001 0.0006 0.0026
Plasmodium falciparum lysine--tRNA ligase 0.0073 0.0464 0.0464
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0807 0.3501
Echinococcus granulosus Smad4 0.001 0.0006 0.0026
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Brugia malayi hypothetical protein 0.0044 0.0256 0.1109
Mycobacterium tuberculosis Conserved protein 0.0038 0.0207 0.1134
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0046 0.0268 0.1163
Plasmodium falciparum histidine--tRNA ligase, putative 0.0011 0.0015 0.0015
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0193 0.2394
Leishmania major lysyl-tRNA synthetase, putative 0.0073 0.0464 0.5748
Trypanosoma brucei glucose transporter 2A 0.0101 0.067 0.8302
Echinococcus multilocularis cpg binding protein 0.003 0.0155 0.0673
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0377 0.4671
Onchocerca volvulus 0.0046 0.0268 0.6813
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0068 0.0844
Onchocerca volvulus 0.0046 0.0268 0.6813
Leishmania major NADH dehydrogenase, putative 0.0009 0.0003 0.0042
Toxoplasma gondii sugar transporter ST1 0.0046 0.0268 0.0404
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0306 0.1321
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0193 0.2394
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0306 0.1328
Onchocerca volvulus Putative transporter 0.0046 0.0268 0.6813
Echinococcus granulosus caspase 2 0.0063 0.0394 0.1707
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0207 0.2566
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0193 0.0838
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0018 0.0068 0.0844
Trypanosoma brucei metacaspase MCA3 0.0019 0.0073 0.09
Echinococcus multilocularis Smad4 0.001 0.0006 0.0026
Echinococcus granulosus intermediate filament protein 0.0033 0.0171 0.0742
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0015 0.0063
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.0807 0.3501
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0664 0.2881
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Schistosoma mansoni lysyl-tRNA synthetase 0.0073 0.0464 0.2002
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0125 0.0541
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0009 0.0003 0.0052
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.0807 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0101 0.067 0.8302
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0664 0.2881
Chlamydia trachomatis aspartate--tRNA(Asp/Asn) ligase 0.0011 0.0015 0.0242
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0193 0.2394
Echinococcus multilocularis caspase 2 0.0063 0.0394 0.1707
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0071 0.2565
Toxoplasma gondii transporter, major facilitator family protein 0.0046 0.0268 0.0404
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0898
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0009 0.0003 0.0015
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0664 0.2881
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0073 0.0315
Echinococcus multilocularis GPCR, family 2 0.0034 0.0184 0.0799
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0011 0.0015 0.0022
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0009 0.0003 0.0018
Trichomonas vaginalis glucose transporter, putative 0.0101 0.067 0.2906
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0664 0.2866
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0015 0.0064
Trichomonas vaginalis sugar transporter, putative 0.0101 0.067 0.2906
Schistosoma mansoni sulfide quinone reductase 0.0009 0.0003 0.0015
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0665 0.1002
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0207 0.1134
Trypanosoma brucei glucose transporter 1E 0.0101 0.067 0.8302
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0665 0.0665
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Onchocerca volvulus 0.0038 0.0207 0.5263
Trypanosoma cruzi metacaspase, putative 0.0019 0.0073 0.09
Entamoeba histolytica hypothetical protein 0.0043 0.025 0.3098
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0015 0.0063
Echinococcus multilocularis lamin dm0 0.0033 0.0171 0.0742
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0207 0.1134
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0035 0.0186 0.2272
Leishmania major hypothetical protein, conserved 0.0038 0.0207 0.2566
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0009 0.0003 0.0005
Brugia malayi Sugar transporter family protein 0.0046 0.0268 0.1163
Trypanosoma cruzi metacaspase, putative 0.0019 0.0073 0.09
Schistosoma mansoni hypothetical protein 0.0034 0.0184 0.0794
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0807 1
Schistosoma mansoni hypothetical protein 0.0009 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Loa Loa (eye worm) beta-lactamase 0.0038 0.0207 0.0898
Schistosoma mansoni caspase-3 (C14 family) 0.0019 0.0073 0.0313
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0015 0.0184
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.017 0.0257
Schistosoma mansoni cpg binding protein 0.0029 0.0143 0.0618
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0011 0.0015 0.0184
Echinococcus granulosus thioredoxin glutathione reductase 0.0103 0.0685 0.2971
Echinococcus multilocularis lamin 0.0033 0.0171 0.0742
Giardia lamblia Asparaginyl-tRNA synthetase 0.0011 0.0015 0.0225
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0061 0.0377 0.0568
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0665 0.0665
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0377 0.1626
Schistosoma mansoni protein kinase 0.0101 0.0664 0.2866
Mycobacterium tuberculosis Conserved protein 0.0038 0.0207 0.1134
Mycobacterium leprae Probable lipase LipE 0.0038 0.0207 0.1134
Toxoplasma gondii lysine-tRNA ligase 0.0073 0.0464 0.0699
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0665 0.1002
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trypanosoma cruzi histidyl-tRNA synthetase 0.0011 0.0015 0.0184
Loa Loa (eye worm) Smad1 0.001 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0038 0.0207 0.0898
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0665 0.0665
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0009 0.0003 0.0042
Trypanosoma cruzi metacaspase, putative 0.0019 0.0073 0.09
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0018 0.0068 0.0296
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0098 0.0646 0.2787
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0018 0.0068 0.0806
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0193 0.4122
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0009 0.0003 0.0042
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0061 0.0377 0.4671
Plasmodium vivax sugar transporter, putative 0.0046 0.0268 0.0268
Treponema pallidum asparaginyl-tRNA synthetase 0.0011 0.0015 0.0139
Toxoplasma gondii facilitative glucose transporter GT1 0.0327 0.2305 0.3474
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0665 0.0665
Onchocerca volvulus 0.0046 0.0268 0.6813
Schistosoma mansoni smad1 5 8 and 0.001 0.0006 0.0026
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0006 0.0026
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0061 0.0266
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0261 0.1826 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0114 0.0764 0.9465
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.017 0.0257
Schistosoma mansoni hypothetical protein 0.0074 0.0473 0.2043
Echinococcus multilocularis General substrate transporter 0.0281 0.1972 0.8554
Schistosoma mansoni sulfide quinone reductase 0.0009 0.0003 0.0015
Trypanosoma cruzi NADH dehydrogenase, putative 0.0009 0.0003 0.0042
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0071 0.0309
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0665 0.0665
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Loa Loa (eye worm) hypothetical protein 0.0034 0.0184 0.0799
Plasmodium vivax lysine--tRNA ligase, putative 0.0073 0.0464 0.0464
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.033 0.0497
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0207 0.1134
Leishmania major aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0171 0.0742
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0071 0.0883
Brugia malayi MH2 domain containing protein 0.0144 0.0981 0.4255
Brugia malayi beta-lactamase 0.0038 0.0207 0.0898
Giardia lamblia Aspartyl-tRNA synthetase 0.0011 0.0015 0.0225
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0193
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0003 0.0015
Toxoplasma gondii protein kinase, putative 0.0924 0.6636 1
Schistosoma mansoni Smad4 0.001 0.0006 0.0026
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0053 0.0652
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0018 0.0068 0.0806
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0073 0.0315
Schistosoma mansoni hypothetical protein 0.0034 0.0184 0.0794
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.017 0.3627
Trichomonas vaginalis glucose transporter, putative 0.0046 0.0268 0.1163
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0009 0.0003 0.0015
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0003 0.0042
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0018 0.0068 0.2447
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Echinococcus granulosus cpg binding protein 0.003 0.0155 0.0673
Onchocerca volvulus 0.0046 0.0268 0.6813
Loa Loa (eye worm) RNA binding protein 0.0076 0.049 0.2125
Schistosoma mansoni threonyl-tRNA synthetase 0.0011 0.0015 0.0064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0073 0.0315
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0071 0.0309
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0981 0.4255
Loa Loa (eye worm) thioredoxin reductase 0.0103 0.0681 0.2952
Echinococcus granulosus solute carrier family 22 0.0046 0.0268 0.1163
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Schistosoma mansoni glucose transport protein 0.0327 0.2305 0.9947
Echinococcus multilocularis solute carrier family 22 0.0046 0.0268 0.1163
Treponema pallidum threonyl-tRNA synthetase 0.0018 0.0068 0.0806
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0193 0.2991
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0193 0.0193
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0061 0.0377 0.4671
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0071 0.0883
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0073 0.0315
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0664 0.2881
Entamoeba histolytica thioredoxin reductase, putative 0.0009 0.0003 0.0042
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.0006 0.0026
Trypanosoma cruzi glucose transporter, putative 0.0046 0.0268 0.3322
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0015 0.0184
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0665 0.0665
Schistosoma mansoni intermediate filament proteins 0.0033 0.0171 0.0738
Echinococcus multilocularis solute carrier family 22 0.0046 0.0268 0.1163
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0234 0.1636 0.896
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0193 0.0193
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0006 0.0026
Onchocerca volvulus 0.0033 0.0171 0.4348
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0009 0.0003 0.0042
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0009 0.0003 0.0042
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0062 0.0384 0.2104
Schistosoma mansoni sugar transporter 0.0046 0.0268 0.1157
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.017 0.0739
Brugia malayi MH2 domain containing protein 0.001 0.0006 0.0026
Echinococcus multilocularis apoptotic protease activating factor 1 0.0044 0.0256 0.1109
Wolbachia endosymbiont of Brugia malayi aspartyl-tRNA synthetase 0.0011 0.0015 0.0422
Toxoplasma gondii exonuclease III APE 0.0019 0.0071 0.0107
Leishmania major glucose transporter, lmgt3 0.0101 0.067 0.8302
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0061 0.0377 0.1635
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0212
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0193 0.0193
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0003 0.0015
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0375 0.2056
Loa Loa (eye worm) hypothetical protein 0.0063 0.0394 0.1707
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0261 0.1826 1
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0193 0.0291
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0018 0.0068 0.0373
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0807 0.3501
Echinococcus granulosus apoptotic protease activating factor 1 0.0044 0.0256 0.1109
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0011 0.0015 0.0063
Schistosoma mansoni hypothetical protein 0.0327 0.2305 0.9947
Toxoplasma gondii sugar transporter ST3 0.0046 0.0268 0.0404
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0016 0.0053 0.0079
Echinococcus granulosus solute carrier family 22 0.0046 0.0268 0.1163
Onchocerca volvulus Cell death protein 3 homolog 0.0063 0.0394 1
Trypanosoma brucei histidyl-tRNA synthetase 0.0011 0.0015 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0053 0.0228
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0018 0.0068 0.0844
Loa Loa (eye worm) hypothetical protein 0.0044 0.0256 0.1109
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0193 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0073 0.0315
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0143 0.0621
Trypanosoma brucei NADH dehydrogenase 0.0009 0.0003 0.0042
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0193 0.2362
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0664 0.2881
Echinococcus granulosus Sugar transporter ERD6 protein 0.0046 0.0268 0.1163
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0003 0.0042
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0268 0.1163
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.004 0.0227 0.0983
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0073 0.0464 0.573
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0098 0.0646 0.2787
Plasmodium vivax metacaspase 1, putative 0.0019 0.0073 0.0073
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0528 0.3769 0.3769
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0377 0.1635
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.0011 0.0015 0.0139
Onchocerca volvulus 0.0033 0.0171 0.4348
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0046 0.0268 0.0268
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0193 0.2394
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0009 0.0003 0.0015
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0098 0.0646 0.2802
Toxoplasma gondii selenide, water dikinase 0.0009 0.0003 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0375 0.162
Mycobacterium ulcerans 6-phosphofructokinase 0.012 0.0807 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0073 0.0109
Brugia malayi hypothetical protein 0.0046 0.0268 0.1163
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0207 0.0898
Plasmodium vivax glutathione reductase, putative 0.0103 0.0681 0.0681
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0009 0.0003 0.0018
Brugia malayi glutamate synthase 0.0009 0.0003 0.0015
Trichomonas vaginalis glucose transporter, putative 0.0101 0.067 0.2906
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0011 0.0015 0.0065
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.017 0.0739
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0018 0.0068 0.0296
Schistosoma mansoni hypothetical protein 0.0034 0.0184 0.0794
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0071 0.0071
Schistosoma mansoni ap endonuclease 0.0019 0.0071 0.0308
Trypanosoma brucei trypanothione reductase 0.0103 0.0681 0.8433
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Mycobacterium ulcerans lipase LipD 0.0038 0.0207 0.2535
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0053 0.0652
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0071 0.0071
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0375 0.0566
Loa Loa (eye worm) glutathione reductase 0.0103 0.0681 0.2952
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0207 0.1134
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0073 0.0464 0.2012
Plasmodium falciparum thioredoxin reductase 0.0103 0.0681 0.0681
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Onchocerca volvulus 0.0046 0.0268 0.6813
Mycobacterium tuberculosis Probable oxidoreductase 0.0261 0.1826 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0009 0.0003 0.0015
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0009 0.0003 0.0018
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0261 0.1826 1
Loa Loa (eye worm) phosphofructokinase 0.012 0.0807 0.3501
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0009 0.0003 0.0015
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0068 0.0844
Trichomonas vaginalis sugar transport protein, putative 0.0046 0.0268 0.1163
Brugia malayi MH1 domain containing protein 0.001 0.0006 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.017 0.0739
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0015 0.0064
Onchocerca volvulus 0.0046 0.0268 0.6813
Schistosoma mansoni 6-phosphofructokinase 0.012 0.0807 0.3482
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0073 0.0464 0.2541
Trypanosoma cruzi hexose transporter, putative 0.0101 0.067 0.8302
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0018 0.0068 0.0296
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0046 0.0268 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Leishmania major hypothetical protein, conserved 0.0009 0.0003 0.0042
Toxoplasma gondii glycyl-tRNA synthetase 0.0018 0.0068 0.0103
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Onchocerca volvulus 0.0044 0.0256 0.6498
Entamoeba histolytica protein kinase, putative 0.0101 0.0664 0.8231
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0053 0.0288
Trypanosoma cruzi trypanothione reductase, putative 0.0103 0.0681 0.8433
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0011 0.0015 0.0063
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0171 0.0742
Mycobacterium tuberculosis Conserved protein 0.0038 0.0207 0.1134
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0207 0.1134
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.017 0.0739
Chlamydia trachomatis lysine--tRNA ligase 0.0073 0.0464 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0207 0.0898
Schistosoma mansoni glycyl-tRNA synthetase 0.0018 0.0068 0.0294
Entamoeba histolytica disulphide oxidoreductase, putative 0.0009 0.0003 0.0042
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0664 0.2881
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.017 0.2638
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0193 0.0838
Entamoeba histolytica protein kinase, putative 0.0101 0.0664 0.8231
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0193 0.7171
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.0011 0.0015 0.0063
Brugia malayi 6-phosphofructokinase 0.012 0.0807 0.3501
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0053 0.0652
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0071 0.0845
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0193
Schistosoma mansoni 6-phosphofructokinase 0.012 0.0807 0.3482
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0807 0.3501
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0807 1
Plasmodium falciparum protein kinase 7 0.0924 0.6636 0.6636
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0327 0.2305 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0064 0.0399 0.1729
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0009 0.0003 0.0015
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0009 0.0003 0.0042
Onchocerca volvulus 0.0046 0.0268 0.6813
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0234 0.1636 0.896
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Giardia lamblia Lysyl-tRNA synthetase 0.0073 0.0464 0.7182
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0046 0.0268 0.1157
Loa Loa (eye worm) 63kd antigen 0.0011 0.0015 0.0063
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0375 0.1629
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0009 0.0003 0.0015
Schistosoma mansoni disulfide oxidoreductase 0.0009 0.0003 0.0015
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0098 0.0646 0.2802
Schistosoma mansoni lamin 0.0033 0.0171 0.0738
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0009 0.0003 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0375 0.463
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0184 0.0799
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0723 0.3135
Echinococcus granulosus caspase 0.0019 0.0073 0.0315
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0207 0.0898
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0207 0.0898
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0114 0.0764 0.9465
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0098 0.0646 0.2802
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0006 0.0026
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0207 0.1134
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0114 0.0764 0.1151
Echinococcus granulosus mitogen activated protein kinase 3 0.0061 0.0377 0.1635
Echinococcus granulosus lysyl tRNA synthetase 0.0073 0.0464 0.2012
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0009 0.0003 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0193 0.2394
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0664 0.8231
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0193 0.2394
Echinococcus multilocularis musashi 0.0033 0.0171 0.0742
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0207 0.2535
Onchocerca volvulus 0.0029 0.0143 0.364
Plasmodium falciparum glycine--tRNA ligase 0.0011 0.0015 0.0015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0377 0.4671
Toxoplasma gondii ABC1 family protein 0.0038 0.0207 0.0312
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0053 0.0288
Loa Loa (eye worm) TAR-binding protein 0.0076 0.049 0.2125
Mycobacterium ulcerans integral membrane transport protein 0.0046 0.0268 0.3294
Brugia malayi MH1 domain containing protein 0.001 0.0006 0.0026
Trypanosoma brucei THT1 - hexose transporter, putative 0.0101 0.067 0.8302
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0098 0.0646 0.3538
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.012 0.0807 1
Trichomonas vaginalis myo-inositol transporter, putative 0.0046 0.0268 0.1163
Trypanosoma cruzi NADH dehydrogenase, putative 0.0009 0.0003 0.0042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0071 0.0883
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0071 0.0883
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0009 0.0003 0.0015
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0184 0.0799
Echinococcus multilocularis histidyl tRNA synthetase 0.0011 0.0015 0.0065
Plasmodium vivax glycine--tRNA ligase, putative 0.0018 0.0068 0.0068
Giardia lamblia Hexose transporter 0.0046 0.0268 0.415
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0009 0.0003 0.0042
Treponema pallidum prolyl-tRNA synthetase 0.0035 0.0186 0.2272
Giardia lamblia Sugar-proton symporter 0.0046 0.0268 0.415
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.0807 1
Plasmodium vivax hexose transporter 0.0327 0.2305 0.2305
Echinococcus multilocularis glycyl tRNA synthetase 0.0018 0.0068 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0053 0.0228
Brugia malayi Smad1 0.001 0.0006 0.0026
Trypanosoma cruzi hexose transporter, putative 0.0055 0.0337 0.4171
Mycobacterium ulcerans hypothetical protein 0.0016 0.0053 0.0613
Echinococcus granulosus caspase 8 0.0019 0.0073 0.0315
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0207 0.2566
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.1675 0.9171
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0009 0.0003 0.0003
Brugia malayi 6-phosphofructokinase 0.012 0.0807 0.3501
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0071 0.0883
Brugia malayi beta-lactamase family protein 0.0038 0.0207 0.0898
Leishmania major glucose transporter, lmgt1 0.0101 0.067 0.8302
Plasmodium falciparum asparagine--tRNA ligase 0.0011 0.0015 0.0015
Brugia malayi glycyl-tRNA synthetase 0.0018 0.0068 0.0296
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0009 0.0003 0.0015
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0003 0.0015
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0073 0.09
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.067 0.2906
Trypanosoma cruzi hexose transporter 0.0101 0.067 0.8302
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0046 0.0268 0.3322
Chlamydia trachomatis histidine--tRNA ligase 0.0011 0.0015 0.025
Leishmania major threonyl-tRNA synthetase, putative 0.0018 0.0068 0.0844
Loa Loa (eye worm) sugar transporter 0.0046 0.0268 0.1163
Plasmodium falciparum glutathione reductase 0.0103 0.0681 0.0681
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0071 0.0309
Loa Loa (eye worm) sugar transporter 0.0327 0.2305 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0114 0.0764 0.9465
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0061 0.0377 0.4671
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0207 0.0207
Leishmania major glucose transporter, lmgt2 0.0101 0.067 0.8302
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0268 0.1163
Mycobacterium tuberculosis Probable reductase 0.0234 0.1636 0.896
Plasmodium falciparum proline--tRNA ligase 0.0114 0.0764 0.0764
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0664 0.2881
Echinococcus multilocularis smad 0.001 0.0006 0.0026
Echinococcus granulosus mitogen activated protein kinase 0.0061 0.0377 0.1635
Schistosoma mansoni lysyl-tRNA synthetase 0.0073 0.0464 0.2002
Echinococcus multilocularis 6 phosphofructokinase 0.012 0.0807 0.3501
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0306 0.1328
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0268 0.1163
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0234 0.1636 0.896
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0071 0.0309
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0009 0.0003 0.0042
Trypanosoma brucei glucose transporter, putative 0.0101 0.067 0.8302
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0009 0.0003 0.0042
Echinococcus granulosus GPCR family 2 0.0034 0.0184 0.0799
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0664 0.2881
Plasmodium falciparum thioredoxin reductase 0.0036 0.0193 0.0193
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.0006 0.0026
Plasmodium vivax ferrodoxin reductase, putative 0.0009 0.0003 0.0003
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0009 0.0003 0.0018
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0015 0.0063
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.0807 0.3501
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0306 0.1328
Giardia lamblia Glycyl-tRNA synthetase 0.0018 0.0068 0.1055
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.049 0.2125
Onchocerca volvulus 0.0046 0.0268 0.6813
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0193 0.2362
Schistosoma mansoni lamin 0.0033 0.0171 0.0738
Brugia malayi CXXC zinc finger family protein 0.0029 0.0143 0.0621
Schistosoma mansoni smad1 5 8 and 0.001 0.0006 0.0026
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0184 0.0799
Leishmania major hypothetical protein, conserved 0.0016 0.0053 0.0652
Onchocerca volvulus 0.0046 0.0268 0.6813
Leishmania major hypothetical protein, conserved 0.0009 0.0003 0.0042
Plasmodium falciparum aspartate--tRNA ligase 0.0011 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0377 0.1635
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.049 0.2125
Brugia malayi beta-lactamase family protein 0.0038 0.0207 0.0898
Echinococcus granulosus 6 phosphofructokinase 0.012 0.0807 0.3501
Brugia malayi MH2 domain containing protein 0.001 0.0006 0.0026
Leishmania major ATP-dependent phosphofructokinase 0.012 0.0807 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0327 0.2305 1
Chlamydia trachomatis threonine--tRNA ligase 0.0018 0.0068 0.1406
Leishmania major myo-inositol/proton symporter (MIT) 0.0046 0.0268 0.3322
Leishmania major trypanothione reductase 0.0103 0.0681 0.8433
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0377 0.1635
Onchocerca volvulus 0.0046 0.0268 0.6813
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0098 0.0646 0.2802
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.1163
Giardia lamblia Prolyl-tRNA synthetase 0.0098 0.0646 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0193 0.0838
Trichomonas vaginalis apoptosis inducing factor, putative 0.0009 0.0003 0.0015
Brugia malayi Cam kinase protein 1 0.0101 0.0664 0.2881
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0207 0.0898
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0046 0.0268 0.3294
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0009 0.0003 0.0018
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0009 0.0003 0.0018
Echinococcus granulosus lamin 0.0033 0.0171 0.0742
Echinococcus multilocularis tar DNA binding protein 0.0076 0.049 0.2125
Chlamydia trachomatis proline--tRNA ligase 0.0035 0.0186 0.3965
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0207 0.0898
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0009 0.0003 0.0018
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0018 0.0068 0.0844
Giardia lamblia Kinase, CMGC MAPK 0.0061 0.0377 0.5836
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0306 0.1328
Leishmania major lysyl-tRNA synthetase, putative 0.0011 0.0015 0.018
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0207 0.1134
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0071 0.0309
Plasmodium falciparum ferrodoxin reductase-like protein 0.0009 0.0003 0.0003
Trypanosoma brucei metacaspase MCA2 0.0019 0.0073 0.09
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0009 0.0003 0.0018
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0073 0.0313
Loa Loa (eye worm) hypothetical protein 0.0032 0.0167 0.0723
Schistosoma mansoni sugar transporter 0.0046 0.0268 0.1157
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0018 0.0068 0.0296
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0009 0.0003 0.0005
Schistosoma mansoni smad1 5 8 and 0.001 0.0006 0.0026
Onchocerca volvulus 0.0046 0.0268 0.6813
Trichomonas vaginalis sugar transporter, putative 0.0101 0.067 0.2906
Echinococcus multilocularis lysyl tRNA synthetase 0.0073 0.0464 0.2012
Echinococcus multilocularis mitogen activated protein kinase 0.0061 0.0377 0.1635
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0171 0.0742
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0073 0.0315
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0184 0.0799
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0009 0.0003 0.0042
Loa Loa (eye worm) hypothetical protein 0.008 0.0513 0.2224
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0306 0.1321
Schistosoma mansoni protein kinase 0.0101 0.0664 0.2866
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Brugia malayi phosphofructokinase 0.012 0.0807 0.3501
Onchocerca volvulus 0.0046 0.0268 0.6813
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0268 0.1163
Entamoeba histolytica hypothetical protein 0.0043 0.025 0.3098
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0009 0.0003 0.0005
Schistosoma mansoni glucose transport protein 0.0327 0.2305 0.9947
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0193 0.2394
Trichomonas vaginalis glutamate synthase, putative 0.0009 0.0003 0.0015
Toxoplasma gondii thioredoxin reductase 0.0103 0.0681 0.1026
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0009 0.0003 0.0015
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0098 0.0646 0.2802
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0011 0.0015 0.0065
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0073 0.09
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0073 0.0464 0.5748
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0193 0.0838
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0011 0.0015 0.0435
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0184 0.0799

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.3162 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 0.3162 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.8913 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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