Detailed information for compound 775424

Basic information

Technical information
  • TDR Targets ID: 775424
  • Name: methyl 2-methyl-5-[(2-methyl-5-nitrophenyl)su lfonylamino]benzo[g][1]benzoxole-3-carboxylat e
  • MW: 454.453 | Formula: C22H18N2O7S
  • H donors: 1 H acceptors: 5 LogP: 4.54 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1cc(ccc1C)[N+](=O)[O-])c1c2cccc1
  • InChi: 1S/C22H18N2O7S/c1-12-8-9-14(24(26)27)10-19(12)32(28,29)23-18-11-17-20(22(25)30-3)13(2)31-21(17)16-7-5-4-6-15(16)18/h4-11,23H,1-3H3
  • InChiKey: PKQRVCQBURJZFU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 2-methyl-5-[(2-methyl-5-nitro-phenyl)sulfonylamino]benzo[g]benzofuran-3-carboxylate
  • 2-methyl-5-[(2-methyl-5-nitrophenyl)sulfonylamino]-3-benzo[g]benzofurancarboxylic acid methyl ester
  • 2-methyl-5-[(2-methyl-5-nitro-phenyl)sulfonylamino]benzo[g]benzofuran-3-carboxylic acid methyl ester
  • methyl 2-methyl-5-[(2-methyl-5-nitro-phenyl)sulfonylamino]benzo[g][1]benzoxole-3-carboxylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis pyruvate kinase 0.0033 0.0114 0.2667
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0059 0.0274 0.5587
Onchocerca volvulus Alhambra homolog 0.0029 0.0088 0.0445
Onchocerca volvulus 0.0044 0.0178 0.1113
Onchocerca volvulus 0.006 0.0281 0.1878
Loa Loa (eye worm) hypothetical protein 0.0036 0.0128 0.0259
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0071 0.1536
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0145 0.2472
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0088 0.0085
Loa Loa (eye worm) MH2 domain-containing protein 0.0353 0.2133 0.4785
Plasmodium falciparum threonine--tRNA ligase 0.0017 0.0013 0.0002
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0033 0.0114 0.0195
Leishmania major lysyl-tRNA synthetase, putative 0.0069 0.034 0.5783
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0145 0.022
Loa Loa (eye worm) RNA binding protein 0.0251 0.1492 0.3339
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0233 0.1253
Schistosoma mansoni hypothetical protein 0.0023 0.0047 0.0068
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0029 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0142 0.076
Onchocerca volvulus 0.0053 0.0239 0.1566
Loa Loa (eye worm) hypothetical protein 0.0036 0.0128 0.0259
Trypanosoma brucei glucosidase, putative 0.0038 0.014 0.2387
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0064 0.0308 0.5161
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0114 0.1941
Onchocerca volvulus 0.0044 0.0178 0.1113
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0391 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0391 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.016 0.2571
Leishmania major hypothetical protein, conserved 0.0051 0.0225 0.3822
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0095 0.0159
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0239 0.051
Toxoplasma gondii lysine-tRNA ligase 0.0069 0.034 0.0625
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0093 0.0491 0.1078
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0108 0.0588 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0391 0.0463
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0029 0.0036
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0114 0.0611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0308 0.1655
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0104
Schistosoma mansoni glucose transport protein 0.031 0.1863 0.3507
Echinococcus multilocularis musashi 0.0053 0.0239 0.0236
Brugia malayi hypothetical protein 0.0033 0.0111 0.0221
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0239 0.051
Schistosoma mansoni lamin 0.0053 0.0239 0.0432
Loa Loa (eye worm) sugar transporter 0.0044 0.0178 0.0373
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0017 0.0013 0.0218
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0095 0.0503 0.1106
Echinococcus granulosus lamin dm0 0.0053 0.0239 0.0365
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0108 0.0588 1
Onchocerca volvulus 0.0053 0.0239 0.1566
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0017 0.0013 0.0096
Schistosoma mansoni survival motor neuron protein 0.0147 0.0829 0.1549
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.1343 0.134
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0225 0.026
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0069 0.034 0.5783
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.014 0.0754
Toxoplasma gondii hypothetical protein 0.0027 0.0071 0.0131
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1492 0.2806
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0145 0.0299
Giardia lamblia GTOR 0.0064 0.0308 0.6197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0114 0.0613
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0029 0.0039
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0029 0.0039
Onchocerca volvulus 0.0152 0.0862 0.6206
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0055 0.0249 0.4229
Plasmodium falciparum calcium-dependent protein kinase 5 0.0095 0.0503 0.0599
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0022 0.0117
Plasmodium falciparum pyruvate kinase 0.0033 0.0114 0.0125
Schistosoma mansoni Smad4 0.0024 0.0055 0.0082
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.005 0.0647
Plasmodium falciparum phd finger protein, putative 0.0029 0.0088 0.0094
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.014 0.2387
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0114 0.0228
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0058 0.0312
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0059 0.0274 0.2045
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0178 0.0956
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.1343 0.2522
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.051 0.274
Brugia malayi lysyl-tRNA synthetase 0.0069 0.034 0.0738
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.016 0.0181
Trypanosoma brucei sugar transporter, putative 0.0044 0.0178 0.303
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0104
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1492 0.2806
Onchocerca volvulus 0.0044 0.0178 0.1113
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0033 0.0114 0.1937
Brugia malayi major facilitator superfamily protein 0.0044 0.0178 0.0373
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0019 0.0022 0.0029
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0086 0.0164
Schistosoma mansoni chromobox protein 0.0067 0.0329 0.0602
Brugia malayi Smad1 0.0024 0.0055 0.0094
Entamoeba histolytica protein kinase, putative 0.0095 0.0503 0.856
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0064 0.0308 0.5241
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0216 0.1159
Schistosoma mansoni lysyl-tRNA synthetase 0.0069 0.034 0.0623
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0712 0.1327
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0228 0.1343 0.3001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0276 0.7038
Trypanosoma brucei glucose transporter 1E 0.0096 0.051 0.868
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Leishmania major glucose transporter/membrane transporter D2, putative 0.0096 0.051 0.868
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0095 0.0503 0.05
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0088 0.0163
Brugia malayi MH2 domain containing protein 0.0024 0.0055 0.0094
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0128 0.0142
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0095 0.0503 0.0774
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0391 0.072
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0018 0.0098
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0225 0.0344
Trypanosoma cruzi hexose transporter, putative 0.0096 0.051 0.868
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0029 0.0036
Onchocerca volvulus 0.016 0.0912 0.6578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0174 0.0932
Onchocerca volvulus 0.0041 0.0165 0.1013
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0095 0.0503 0.05
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0312
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0029 0.0039
Mycobacterium tuberculosis Conserved protein 0.0036 0.0128 0.0952
Brugia malayi Calcitonin receptor-like protein seb-1 0.0161 0.0922 0.2052
Leishmania major myo-inositol/proton symporter (MIT) 0.0044 0.0178 0.303
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Schistosoma mansoni glucose transport protein 0.031 0.1863 0.3507
Plasmodium falciparum lysine--tRNA ligase 0.0069 0.034 0.0401
Leishmania major glucose transporter, lmgt3 0.0096 0.051 0.868
Loa Loa (eye worm) hypothetical protein 0.0036 0.0128 0.0259
Schistosoma mansoni nuclear hormone receptor 0.002 0.0029 0.0033
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0225 0.0479
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0096 0.051 0.274
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0128 0.0685
Echinococcus granulosus serine protein kinase ATM 0.0033 0.0114 0.0171
Trypanosoma cruzi target of rapamycin kinase 3 0.0055 0.0249 0.4229
Onchocerca volvulus 0.0232 0.1372 1
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0071 0.1447
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0012 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0248 0.1334
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0178 0.0956
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0044 0.0178 0.1329
Brugia malayi Sugar transporter family protein 0.0044 0.0178 0.0373
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0017 0.0013 0.0328
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.017 0.0974 0.2169
Trichomonas vaginalis esterase, putative 0.0036 0.0128 0.0685
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.014 0.0754
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.1343 0.134
Plasmodium vivax SET domain protein, putative 0.003 0.0095 0.0102
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Brugia malayi jmjC domain containing protein 0.0039 0.0149 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0174 0.0933
Brugia malayi hypothetical protein 0.0119 0.0655 0.1449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0174 0.0933
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0095 0.0159
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0114 0.0229
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0391 1
Echinococcus granulosus solute carrier family 22 0.0044 0.0178 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0178 0.0956
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0093 0.0491 0.8348
Chlamydia trachomatis proline--tRNA ligase 0.0033 0.011 0.2573
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0019 0.0022 0.0019
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0044 0.0178 0.0317
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1492 0.2806
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0128 0.2171
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0093 0.0491 0.1078
Echinococcus granulosus smad 0.0024 0.0055 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0114 0.0613
Onchocerca volvulus 0.0147 0.0829 0.596
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0029 0.0025
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0128 0.0952
Giardia lamblia Lysyl-tRNA synthetase 0.0069 0.034 0.6861
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0114 0.2907
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0128 0.3261
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0114 0.0611
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Schistosoma mansoni pyruvate kinase 0.0033 0.0114 0.0195
Loa Loa (eye worm) hypothetical protein 0.0036 0.0128 0.0259
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Loa Loa (eye worm) hypothetical protein 0.0033 0.0114 0.0228
Echinococcus multilocularis solute carrier family 22 0.0044 0.0178 0.0175
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.031 0.1863 0.186
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0114 0.1941
Giardia lamblia Threonyl-tRNA synthetase 0.0017 0.0013 0.0038
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0029 0.0033
Brugia malayi beta-lactamase family protein 0.0036 0.0128 0.0259
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0142 0.0841
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0191
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0114 0.0111
Schistosoma mansoni hypothetical protein 0.0526 0.3226 0.6089
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0055 0.0249 0.4229
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0161 0.0158
Schistosoma mansoni cellular tumor antigen P53 0.0152 0.0862 0.1612
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0055 0.0051
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0069 0.034 0.5783
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0033 0.0114 0.1937
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0029 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0174 0.0933
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.0012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0108 0.0585 0.0582
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.014 0.0212
Schistosoma mansoni cpg binding protein 0.0063 0.0302 0.0552
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0095 0.0503 0.855
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0029 0.0036
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0035 0.06
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0095 0.0092
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0058 0.0312
Brugia malayi Major Facilitator Superfamily protein 0.0044 0.0178 0.0373
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0108 0.0585 0.0902
Plasmodium vivax calcium-dependent protein kinase, putative 0.0095 0.0503 0.0599
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.008 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0029 0.0036
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0017 0.0013 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.017 0.0912
Brugia malayi Probable ClpP-like protease 0.0077 0.0391 0.0854
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0093 0.0491 0.0487
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0161 0.0922 0.2052
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0145 0.2472
Brugia malayi latrophilin 2 splice variant baaae 0.011 0.06 0.1324
Loa Loa (eye worm) hypothetical protein 0.0093 0.0491 0.1078
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0974 0.0971
Brugia malayi hypothetical protein 0.0108 0.0585 0.1291
Plasmodium falciparum calcium-dependent protein kinase 3 0.0095 0.0503 0.0599
Trypanosoma brucei THT1 - hexose transporter, putative 0.0096 0.051 0.868
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0095 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.031 0.1863 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0114 0.0849
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0286 0.0617
Giardia lamblia PHD finger protein 15 0.0029 0.0088 0.1615
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0225 0.0222
Plasmodium falciparum protein kinase 7 0.0876 0.5441 0.6613
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0128 0.2602
Onchocerca volvulus 0.0044 0.0178 0.1113
Plasmodium falciparum calcium-dependent protein kinase 1 0.0095 0.0503 0.0599
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0391 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0065 0.0095
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0093 0.0491 0.0908
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.016 0.0976
Schistosoma mansoni protein kinase 0.0095 0.0503 0.0931
Toxoplasma gondii facilitative glucose transporter GT1 0.031 0.1863 0.3424
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0044 0.0178 0.0175
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1492 0.2806
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0128 0.0952
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0059 0.0274 0.2045
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0095 0.0159
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0011 0.002
Echinococcus granulosus tumor protein p63 0.1037 0.6457 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0276 0.7038
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0017 0.0013 0.0262
Toxoplasma gondii FATC domain-containing protein 0.0033 0.0114 0.0209
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0391 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0974 0.0971
Echinococcus multilocularis survival motor neuron protein 1 0.0718 0.4445 0.4443
Leishmania major protein kinase, putative 0.0095 0.0503 0.855
Echinococcus multilocularis pyruvate kinase 0.0033 0.0114 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0072 0.0385
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0029 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0029 0.0036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0064 0.0101
Schistosoma mansoni chromobox protein 0.0067 0.0329 0.0602
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0095 0.0503 0.0925
Onchocerca volvulus Huntingtin homolog 0.0119 0.0655 0.4665
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0145 0.3501
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0029 0.0036
Brugia malayi hypothetical protein 0.0051 0.0225 0.0478
Onchocerca volvulus 0.0044 0.0178 0.1113
Echinococcus granulosus pyruvate kinase 0.0033 0.0114 0.0171
Loa Loa (eye worm) hypothetical protein 0.0069 0.034 0.0738
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.014 0.0258
Onchocerca volvulus 0.0044 0.0178 0.1113
Brugia malayi hypothetical protein 0.0044 0.0178 0.0373
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0064 0.0308 0.5241
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0019 0.0022 0.0158
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0114 0.1941
Schistosoma mansoni alpha glucosidase 0.0038 0.014 0.0245
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0329 0.1766
Trichomonas vaginalis sugar transporter, putative 0.0096 0.051 0.274
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0064 0.0308 0.5241
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0145 0.2472
Plasmodium vivax proline--tRNA ligase, putative 0.0108 0.0588 0.0703
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0239 0.051
Onchocerca volvulus 0.0044 0.0178 0.1113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0029 0.0036
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0114 0.0209
Mycobacterium ulcerans integral membrane transport protein 0.0044 0.0178 0.4551
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0128 0.0259
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0095 0.0503 0.1106
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0095 0.0503 0.05
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0095 0.0503 0.1106
Plasmodium falciparum hexose transporter 0.031 0.1863 0.2255
Echinococcus granulosus calcium dependent protein kinase 0.0089 0.0466 0.0716
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0391 0.0463
Plasmodium falciparum calcium-dependent protein kinase 4 0.0095 0.0503 0.0599
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.031 0.1863 0.2881
Trypanosoma brucei THT1 - hexose transporter, putative 0.0096 0.051 0.868
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0064 0.0308 0.0305
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0029 0.0039
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0225 0.0222
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0038 0.0144 0.0296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0141 0.0758
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.014 0.0754
Brugia malayi beta-lactamase 0.0036 0.0128 0.0259
Echinococcus granulosus General substrate transporter 0.0266 0.1587 0.2454
Echinococcus multilocularis Smad4 0.0024 0.0055 0.0051
Brugia malayi hypothetical protein 0.0718 0.4445 1
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0142 0.076
Onchocerca volvulus 0.003 0.009 0.0456
Brugia malayi TAR-binding protein 0.0251 0.1492 0.3339
Schistosoma mansoni sugar transporter 0.0044 0.0178 0.0317
Loa Loa (eye worm) hypothetical protein 0.0036 0.0128 0.0259
Echinococcus multilocularis solute carrier family 22 0.0044 0.0178 0.0175
Mycobacterium ulcerans sugar transporter 0.0044 0.0178 0.4551
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0114 0.0172
Brugia malayi Heterochromatin protein 1 0.0067 0.0329 0.0713
Trichomonas vaginalis myo-inositol transporter, putative 0.0044 0.0178 0.0956
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0114 0.232
Toxoplasma gondii transporter, major facilitator family protein 0.0044 0.0178 0.0327
Brugia malayi beta-lactamase family protein 0.0036 0.0128 0.0259
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0017 0.0013 0.0024
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0095 0.0092
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0501 0.307 0.3725
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0128 0.0193
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0114 0.0228
Trichomonas vaginalis glucose transporter, putative 0.0096 0.051 0.274
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0228 0.1343 0.3001
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0095 0.0142
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0114 0.0125
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.003 0.0095 0.162
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0064 0.0308 0.0472
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0114 0.1935
Schistosoma mansoni hypothetical protein 0.0147 0.0829 0.1549
Loa Loa (eye worm) acetyltransferase 0.0151 0.0857 0.1906
Brugia malayi Glycosyl hydrolases family 31 protein 0.017 0.0974 0.2169
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0064 0.0308 0.0563
Echinococcus granulosus synaptic vesicle 2 protein 0.0044 0.0178 0.0271
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0128 0.3261
Loa Loa (eye worm) histone methyltransferase 0.002 0.0026 0.0031
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0095 0.0503 0.0925
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0503 0.2699
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0029 0.0036
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0029 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0501 0.307 0.5643
Onchocerca volvulus 0.0044 0.0178 0.1113
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0055 0.0094
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Giardia lamblia Pyruvate kinase 0.0033 0.0114 0.2144
Schistosoma mansoni hypothetical protein 0.011 0.06 0.1115
Loa Loa (eye worm) hypothetical protein 0.0095 0.0503 0.1106
Echinococcus granulosus Smad4 0.0024 0.0055 0.0079
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0128 0.0952
Echinococcus multilocularis smad 0.0024 0.0055 0.0051
Loa Loa (eye worm) hypothetical protein 0.0076 0.038 0.0829
Loa Loa (eye worm) hypothetical protein 0.0052 0.0233 0.0496
Onchocerca volvulus 0.0036 0.0128 0.0737
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0114 0.0228
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Plasmodium vivax glycine--tRNA ligase, putative 0.0017 0.0013 0.0002
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0114 0.0228
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0391 0.0388
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Plasmodium vivax CDK-related protein kinase 6, putative 0.1316 0.8222 1
Brugia malayi follicle stimulating hormone receptor 0.0225 0.1325 0.2961
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0165 0.0291
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.0012
Mycobacterium ulcerans beta-lactamase 0.0036 0.0128 0.3261
Schistosoma mansoni smad1 5 8 and 0.0024 0.0055 0.0082
Schistosoma mansoni protein kinase 0.0095 0.0503 0.0931
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0055 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0174 0.0932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0174 0.0933
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0145 0.2472
Toxoplasma gondii protein kinase, putative 0.0876 0.5441 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0053 0.0239 0.051
Brugia malayi RNA binding protein 0.0251 0.1492 0.3339
Mycobacterium leprae Probable lipase LipE 0.0036 0.0128 0.2602
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.1343 0.2522
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0183 0.0984
Echinococcus multilocularis chromobox protein 1 0.0067 0.0329 0.0326
Onchocerca volvulus 0.0036 0.0128 0.0737
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0084
Brugia malayi nuclear hormone receptor 0.002 0.0029 0.0036
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0114 0.0229
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0114 0.0195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0051
Leishmania major threonyl-tRNA synthetase, putative 0.0017 0.0013 0.0218
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0831 0.1282
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0391 0.072
Plasmodium vivax threonine--tRNA ligase, putative 0.0017 0.0013 0.0002
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0857 0.1603
Echinococcus multilocularis geminin 0.0526 0.3226 0.3224
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0029 0.0025
Entamoeba histolytica hypothetical protein 0.0108 0.0585 1
Echinococcus granulosus pyruvate kinase 0.0033 0.0114 0.0171
Trypanosoma cruzi hexose transporter, putative 0.0096 0.051 0.868
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0093 0.0491 0.0908
Loa Loa (eye worm) hypothetical protein 0.016 0.0912 0.2029
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0026 0.0036
Schistosoma mansoni hypothetical protein 0.031 0.1863 0.3507
Schistosoma mansoni lamin 0.0053 0.0239 0.0432
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0088 0.0171
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.005 0.0084
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0225 0.1325 0.2961
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0064 0.0308 0.0667
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0329 0.1766
Giardia lamblia Sugar-proton symporter 0.0044 0.0178 0.3486
Giardia lamblia Hexose transporter 0.0044 0.0178 0.3486
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0178 0.0956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0233 0.1253
Echinococcus granulosus cpg binding protein 0.0063 0.0302 0.0463
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0189 0.1014
Plasmodium vivax lysine--tRNA ligase, putative 0.0069 0.034 0.0401
Brugia malayi hypothetical protein 0.016 0.0912 0.2029
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0128 0.0685
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0145 0.0142
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) hypothetical protein 0.0152 0.0862 0.1916
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.014 0.0754
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0183 0.0984
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0308 0.1655
Loa Loa (eye worm) hypothetical protein 0.0051 0.0225 0.0478
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0064 0.0308 0.5241
Toxoplasma gondii glycyl-tRNA synthetase 0.0017 0.0013 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0029 0.0033
Echinococcus granulosus lysosomal alpha glucosidase 0.017 0.0974 0.1504
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0093 0.0491 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.031 0.1863 0.186
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0114 0.1935
Loa Loa (eye worm) hypothetical protein 0.011 0.06 0.1324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0003 0.0015
Schistosoma mansoni thyroid hormone receptor 0.002 0.0029 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0141 0.0758
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0029 0.0036
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0114 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0114 0.0611
Plasmodium falciparum calcium-dependent protein kinase 2 0.0095 0.0503 0.0599
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0095 0.0503 0.05
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0223 0.1664
Loa Loa (eye worm) beta-lactamase 0.0036 0.0128 0.0259
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0114 0.1935
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0029 0.0039
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0145 0.3501
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0128 0.0952
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0017 0.0013 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0029 0.0036
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0114 0.0228
Leishmania major hypothetical protein, conserved 0.0044 0.0178 0.303
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Brugia malayi Cam kinase protein 1 0.0095 0.0503 0.1106
Schistosoma mansoni hypothetical protein 0.0852 0.5291 1
Schistosoma mansoni fkbp-rapamycin associated protein 0.0019 0.0022 0.0021
Toxoplasma gondii sugar transporter ST3 0.0044 0.0178 0.0327
Brugia malayi jmjC domain containing protein 0.0096 0.0511 0.1125
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0021 0.0036 0.0065
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.031 0.1863 0.2881
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0022 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0128 0.0221
Mycobacterium tuberculosis Conserved protein 0.0036 0.0128 0.0952
Echinococcus granulosus lamin 0.0053 0.0239 0.0365
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0145 0.0781
Schistosoma mansoni hypothetical protein 0.0051 0.0225 0.0406
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0017 0.0013 0.0328
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0029 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0128 0.0685
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0047 0.0044
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0145 0.0164
Brugia malayi Pre-SET motif family protein 0.0204 0.1194 0.2666
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Schistosoma mansoni hypothetical protein 0.0051 0.0225 0.0406
Echinococcus multilocularis General substrate transporter 0.0266 0.1587 0.1584
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0145 0.1084
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0029 0.0039
Echinococcus multilocularis calcium dependent protein kinase 0.0089 0.0466 0.0462
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.0012
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0149 0.0226
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.031 0.1863 0.2881
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0511 0.0787
Schistosoma mansoni hypothetical protein 0.0051 0.0225 0.0406
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0225 0.3822
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.014 0.0754
Brugia malayi Major Facilitator Superfamily protein 0.0044 0.0178 0.0373
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0017 0.0013 0.0218
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0044 0.0178 0.0204
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Trichomonas vaginalis sugar transport protein, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.002
Echinococcus granulosus Threonyl tRNA synthetase C 0.0017 0.0013 0.0015
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0857 0.0854
Echinococcus granulosus tar DNA binding protein 0.0251 0.1492 0.2307
Trypanosoma cruzi hexose transporter, putative 0.0053 0.0235 0.3994
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0225 0.026
Echinococcus multilocularis GPCR, family 2 0.0051 0.0225 0.0222
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0108 0.0588 1
Brugia malayi MH2 domain containing protein 0.0024 0.0055 0.0094
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Entamoeba histolytica protein kinase, putative 0.0095 0.0503 0.856
Echinococcus multilocularis solute carrier family 22 0.0044 0.0178 0.0175
Treponema pallidum prolyl-tRNA synthetase 0.0033 0.011 0.2573
Echinococcus multilocularis pyruvate kinase 0.0033 0.0114 0.0111
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0095 0.0503 0.0599
Trichomonas vaginalis chromobox protein, putative 0.0041 0.016 0.0857
Loa Loa (eye worm) hypothetical protein 0.005 0.0221 0.047
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0095 0.0503 0.0774
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0029 0.0025
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.014 0.0754
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.014 0.2228
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0276 0.0501
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0391 0.0721
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0114 0.1941
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0022 0.0117
Schistosoma mansoni sugar transporter 0.0044 0.0178 0.0317
Loa Loa (eye worm) sugar transporter 0.031 0.1863 0.4174
Schistosoma mansoni glycyl-tRNA synthetase 0.0017 0.0013 0.0003
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0183 0.0279
Loa Loa (eye worm) major facilitator superfamily transporter 0.0044 0.0178 0.0373
Echinococcus multilocularis peregrin 0.0033 0.0112 0.0109
Echinococcus multilocularis lysyl tRNA synthetase 0.0069 0.034 0.0337
Schistosoma mansoni sugar transporter 0.0044 0.0178 0.0317
Plasmodium vivax hexose transporter 0.031 0.1863 0.2255
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0029 0.0036
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0233 0.1253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0141 0.0758
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0018 0.0098
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0073 0.1244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0248 0.1334
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.031 0.1863 0.186
Schistosoma mansoni ap endonuclease 0.0038 0.0145 0.0255
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0114 0.0634
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0276 0.0422
Schistosoma mansoni smad1 5 8 and 0.0024 0.0055 0.0082
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0047 0.0068
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0225 0.3822
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0044 0.0178 0.303
Brugia malayi Pre-SET motif family protein 0.003 0.0095 0.0185
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0128 0.0124
Loa Loa (eye worm) hypothetical protein 0.0036 0.0128 0.0259
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0312
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0149 0.0308
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.1341 1
Echinococcus multilocularis solute carrier family 22 0.0044 0.0178 0.0175
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0225 0.026
Echinococcus multilocularis pyruvate kinase 0.0026 0.0069 0.0066
Schistosoma mansoni protein kinase 0.0095 0.0503 0.0931
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.1343 0.2522
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0029 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0308 0.1655
Schistosoma mansoni coup transcription factor 0.002 0.0029 0.0033
Loa Loa (eye worm) major facilitator superfamily transporter 0.0044 0.0178 0.0373
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0225 0.0344
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.014 0.0288
Entamoeba histolytica hypothetical protein 0.0108 0.0585 1
Onchocerca volvulus 0.0036 0.0128 0.0737
Loa Loa (eye worm) transcription factor SMAD2 0.0353 0.2133 0.4785
Echinococcus granulosus Sugar transporter ERD6 protein 0.0044 0.0178 0.0271
Echinococcus multilocularis cpg binding protein 0.0063 0.0302 0.0299
Brugia malayi chromobox protein homolog 3 0.0038 0.0142 0.029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0312
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.014 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0156 0.0839
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0114 0.0634
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0391 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0128 0.2171
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0095 0.0503 0.0599
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0145 0.2316
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0183 0.0337
Schistosoma mansoni alpha-glucosidase 0.0146 0.0825 0.1542
Echinococcus granulosus geminin 0.0526 0.3226 0.4993
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0147 0.0829 0.1842
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0029 0.0036
Giardia lamblia Glycyl-tRNA synthetase 0.0017 0.0013 0.0038
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0128 0.0952
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0276 0.4685
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0017 0.0013 0.0069
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0029 0.0025
Onchocerca volvulus 0.0044 0.0178 0.1113
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0029 0.0025
Entamoeba histolytica protein kinase rad3, putative 0.0019 0.0022 0.0158
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0128 0.0952
Mycobacterium ulcerans lipase LipD 0.0036 0.0128 0.3261
Toxoplasma gondii sugar transporter ST2 0.0044 0.0178 0.0327
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1372 0.7363
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0329 0.0713
Loa Loa (eye worm) hypothetical protein 0.0051 0.0225 0.0479
Trypanosoma cruzi hexose transporter, putative 0.0096 0.051 0.868
Trypanosoma cruzi hexose transporter, putative 0.0044 0.0178 0.303
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0088 0.0094
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0029 0.0033
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0225 0.0479
Chlamydia trachomatis lysine--tRNA ligase 0.0069 0.034 0.8642
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0128 0.0124
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0108 0.0588 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0055 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0072 0.0385
Schistosoma mansoni hypothetical protein 0.0051 0.0225 0.0406
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0029 0.0033
Echinococcus multilocularis tumor protein p63 0.1037 0.6457 0.6456
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0044 0.0178 0.4551
Schistosoma mansoni intermediate filament proteins 0.0053 0.0239 0.0432
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0029 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0128 0.0685
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Toxoplasma gondii ABC1 family protein 0.0036 0.0128 0.0235
Schistosoma mansoni cpg binding protein 0.0063 0.0302 0.0552
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0064 0.0308 0.5241
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0145 0.2802
Echinococcus multilocularis tar DNA binding protein 0.0251 0.1492 0.149
Leishmania major glucose transporter, lmgt2 0.0096 0.051 0.868
Brugia malayi hypothetical protein 0.0044 0.0178 0.0373
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0095 0.0503 0.0774
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0008
Schistosoma mansoni lysyl-tRNA synthetase 0.0069 0.034 0.0623
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0276 0.0272
Echinococcus multilocularis lamin dm0 0.0053 0.0239 0.0236
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.014 0.2228
Giardia lamblia Prolyl-tRNA synthetase 0.0093 0.0491 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0029 0.0036
Brugia malayi ecdysteroid receptor 0.002 0.0029 0.0036
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0029 0.0033
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0511 0.0508
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0233 0.1253
Schistosoma mansoni hypothetical protein 0.0526 0.3226 0.6089
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0029 0.0036
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0281 0.0605
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.014 0.0754
Loa Loa (eye worm) hypothetical protein 0.0038 0.0142 0.029
Loa Loa (eye worm) hypothetical protein 0.0093 0.0491 0.1078
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.1343 0.2075
Schistosoma mansoni smad 0.0024 0.0055 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0174 0.0932
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0029 0.0025
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.014 0.0754
Echinococcus granulosus chromobox protein 1 0.0067 0.0329 0.0504
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0055 0.0094
Echinococcus granulosus survival motor neuron protein 1 0.0718 0.4445 0.6881
Echinococcus granulosus dnaJ subfamily B 0.0852 0.5291 0.8192
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0095 0.0503 0.0774
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0225 0.3822
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Leishmania major pyruvate kinase 0.0033 0.0114 0.1935
Toxoplasma gondii sugar transporter ST1 0.0044 0.0178 0.0327
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0223 0.4546
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0063 0.1063
Schistosoma mansoni pyruvate kinase 0.0033 0.0114 0.0195
Onchocerca volvulus Huntingtin homolog 0.0119 0.0655 0.4665
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.014 0.0754
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0064 0.0308 0.5161
Brugia malayi Major Facilitator Superfamily protein 0.0044 0.0178 0.0373
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0044 0.0178 0.1329
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0044 0.0178 0.4551
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0055 0.0079
Schistosoma mansoni tar DNA-binding protein 0.0251 0.1492 0.2806
Plasmodium falciparum proline--tRNA ligase 0.0108 0.0588 0.0703
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0223 0.1664
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0083 0.0158
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0114 0.1941
Schistosoma mansoni thyroid hormone receptor 0.002 0.0029 0.0033
Leishmania major pyruvate kinase 0.0033 0.0114 0.1935
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0276 0.2055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0029 0.0036
Echinococcus multilocularis lamin 0.0053 0.0239 0.0236
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0183 0.021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0276 0.7038
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0093 0.0491 0.0755
Echinococcus granulosus intermediate filament protein 0.0053 0.0239 0.0365
Entamoeba histolytica hypothetical protein 0.0108 0.0585 1
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0029 0.0036
Echinococcus granulosus GPCR family 2 0.0051 0.0225 0.0344
Echinococcus granulosus peregrin 0.0033 0.0112 0.0168
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0251 0.1492 0.3339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0248 0.1334
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0071 0.0073
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.031 0.1863 0.2881
Trichomonas vaginalis glucose transporter, putative 0.0044 0.0178 0.0956
Trichomonas vaginalis glucose transporter, putative 0.0096 0.051 0.274
Loa Loa (eye worm) hypothetical protein 0.0029 0.0088 0.0171
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0017 0.0013 0.001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0145 0.0299
Brugia malayi MH1 domain containing protein 0.0024 0.0055 0.0094
Echinococcus multilocularis chromobox protein 1 0.0067 0.0329 0.0326
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Echinococcus granulosus solute carrier family 22 0.0044 0.0178 0.0271
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.014 0.2387
Schistosoma mansoni transcription factor LCR-F1 0.0108 0.0585 0.1088
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0033 0.011 0.2817
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0065 0.0062
Loa Loa (eye worm) hypothetical protein 0.003 0.0095 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0114 0.0613
Onchocerca volvulus 0.0098 0.0522 0.3677
Loa Loa (eye worm) hypothetical protein 0.0119 0.0655 0.1449
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0223 0.034
Entamoeba histolytica hypothetical protein 0.0069 0.034 0.5717
Mycobacterium ulcerans hypothetical protein 0.0036 0.0128 0.3261
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0276 0.0506
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.1343 0.2075
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0145 0.0781
Echinococcus granulosus solute carrier family 22 0.0044 0.0178 0.0271
Brugia malayi PHD-finger family protein 0.0029 0.0088 0.0171
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0114 0.1941
Echinococcus multilocularis dnaJ subfamily B 0.0852 0.5291 0.5289
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0128 0.0221
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0029 0.0036
Brugia malayi nuclear receptor NHR-88 0.002 0.0029 0.0036
Schistosoma mansoni alpha-glucosidase 0.0146 0.0825 0.1542
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0061 0.0286 0.1536
Schistosoma mansoni hypothetical protein 0.0029 0.0088 0.0147
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0161 0.0922 0.2052
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0008
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0149 0.0262
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0114 0.1935
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0233 0.1253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0029 0.0036
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0095 0.0503 0.0599
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0386 0.0711
Echinococcus granulosus lysyl tRNA synthetase 0.0069 0.034 0.0522
Plasmodium vivax sugar transporter, putative 0.0044 0.0178 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Schistosoma mansoni cpg binding protein 0.006 0.0281 0.0511
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0008
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0223 0.022
Brugia malayi intermediate filament protein 0.0053 0.0239 0.051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0029 0.0025
Onchocerca volvulus 0.0044 0.0178 0.1113
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0225 0.0413
Loa Loa (eye worm) hypothetical protein 0.0161 0.0922 0.2052
Trichomonas vaginalis sugar transporter, putative 0.0096 0.051 0.274
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.031 0.1863 0.186
Onchocerca volvulus Putative transporter 0.0044 0.0178 0.1113
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Toxoplasma gondii exonuclease III APE 0.0038 0.0145 0.0267
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Brugia malayi major facilitator superfamily protein 0.0044 0.0178 0.0373
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0373
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0029 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0312
Loa Loa (eye worm) Smad1 0.0024 0.0055 0.0094
Schistosoma mansoni smad1 5 8 and 0.0024 0.0055 0.0082
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Schistosoma mansoni glucose transport protein 0.031 0.1863 0.3507
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Entamoeba histolytica hypothetical protein 0.0033 0.0114 0.1766
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0225 0.0479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0248 0.1334
Plasmodium falciparum protein kinase 6 0.1316 0.8222 1
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.016 0.3106
Brugia malayi RNA recognition motif domain containing protein 0.0251 0.1492 0.3339
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0095 0.0503 0.0925
Brugia malayi Bromodomain containing protein 0.0033 0.0112 0.0223
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0145 0.0164
Brugia malayi Sugar transporter family protein 0.0044 0.0178 0.0373
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0108 0.0588 0.1081
Leishmania major glucose transporter, lmgt1 0.0096 0.051 0.868
Schistosoma mansoni hypothetical protein 0.0108 0.0585 0.1088
Schistosoma mansoni glucose transporter 0.0044 0.0178 0.0317
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0088 0.0147
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0029 0.0036
Mycobacterium tuberculosis Conserved protein 0.0036 0.0128 0.0952
Echinococcus multilocularis synaptic vesicle 2 protein 0.0044 0.0178 0.0175
Leishmania major hypothetical protein, conserved 0.0036 0.0128 0.2171
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0029 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.014 0.2387
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0149 0.0262
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0128 0.0259
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0503 0.0931
Schistosoma mansoni sugar transporter 0.0044 0.0178 0.0317
Trypanosoma cruzi sugar transporter, putative 0.0044 0.0178 0.303
Onchocerca volvulus 0.0044 0.0178 0.1113
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0029 0.0033
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0183 0.0337
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0069 0.034 0.8687
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0248 0.1334
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0069 0.034 0.6932
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0391 0.0601
Brugia malayi Sugar transporter family protein 0.031 0.1863 0.4174
Onchocerca volvulus 0.0044 0.0178 0.1113
Onchocerca volvulus 0.0044 0.0178 0.1113
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0178 0.0956
Brugia malayi MH2 domain containing protein 0.0353 0.2133 0.4785
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0114 0.0613
Brugia malayi CXXC zinc finger family protein 0.006 0.0281 0.0605
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0857 0.1906
Echinococcus granulosus glycyl tRNA synthetase 0.0017 0.0013 0.0015
Trypanosoma cruzi hexose transporter 0.0096 0.051 0.868
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0312
Loa Loa (eye worm) phosphatidylinositol 3 0.0064 0.0308 0.0667
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0026 0.0023
Plasmodium falciparum mitogen-activated protein kinase 2 0.0501 0.307 0.3725
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0391 0.798
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0064 0.0308 0.5241
Loa Loa (eye worm) hypothetical protein 0.0718 0.4445 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0029 0.0039
Toxoplasma gondii target of rapamycin (TOR), putative 0.0052 0.0233 0.0429
Onchocerca volvulus 0.0044 0.0178 0.1113
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0161 0.0245
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0128 0.0685
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0036
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0276 0.0501
Trypanosoma cruzi glucose transporter, putative 0.0044 0.0178 0.303
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0035 0.06
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.014 0.0288
Loa Loa (eye worm) hypothetical protein 0.0077 0.0391 0.0854
Echinococcus granulosus chromobox protein 1 0.0067 0.0329 0.0504
Brugia malayi steroid hormone receptor 0.002 0.0029 0.0036
Onchocerca volvulus 0.0044 0.0178 0.1113
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0071 0.0073
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0093 0.0491 0.2634
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0128 0.0952
Trypanosoma brucei glucose transporter, putative 0.0096 0.051 0.868
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0058 0.0312
Loa Loa (eye worm) hypothetical protein 0.0119 0.0655 0.1449
Schistosoma mansoni ap endonuclease 0.0038 0.0145 0.0255
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0108 0.0588 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0189 0.1014
Brugia malayi hypothetical protein 0.0044 0.0178 0.0373
Onchocerca volvulus 0.0044 0.0178 0.1113
Echinococcus granulosus solute carrier family 22 0.0044 0.0178 0.0271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0233 0.1253
Entamoeba histolytica hypothetical protein 0.0108 0.0585 1
Trichomonas vaginalis sugar transporter, putative 0.0044 0.0178 0.0956
Echinococcus granulosus FTZ F1 alpha 0.002 0.0029 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0233 0.1253
Loa Loa (eye worm) TAR-binding protein 0.0251 0.1492 0.3339
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.051 0.274
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0019 0.0022 0.0372
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0044 0.0178 0.4366
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0088 0.0132
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0083 0.0158
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0055 0.0079
Echinococcus multilocularis glycyl tRNA synthetase 0.0017 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0073 0.0136
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0649 0.1194
Trichomonas vaginalis chromobox protein, putative 0.0041 0.016 0.0857
Echinococcus multilocularis serine protein kinase ATM 0.0033 0.0114 0.0111
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0069 0.034 0.8687
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0145 0.3714
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0114 0.0613
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1194 0.2666
Brugia malayi MH1 domain containing protein 0.0024 0.0055 0.0094
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0088 0.0163
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0128 0.2171
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0069 0.034 0.1826
Trypanosoma brucei THT1 - hexose transporter, putative 0.0096 0.051 0.868
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0114 0.0634
Trypanosoma brucei glucose transporter 2A 0.0096 0.051 0.868

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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