Detailed information for compound 78720

Basic information

Technical information
  • TDR Targets ID: 78720
  • Name: 6-[3-(hydroxymethyl)anilino]-1H-pyrimidine-2, 4-dione
  • MW: 233.223 | Formula: C11H11N3O3
  • H donors: 4 H acceptors: 5 LogP: 1.15 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCc1cccc(c1)Nc1cc(O)nc(n1)O
  • InChi: 1S/C11H11N3O3/c15-6-7-2-1-3-8(4-7)12-9-5-10(16)14-11(17)13-9/h1-5,15H,6H2,(H3,12,13,14,16,17)
  • InChiKey: LFVQXHLWCQGROF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-[[3-(hydroxymethyl)phenyl]amino]-1H-pyrimidine-2,4-dione
  • 6-(3-methylolanilino)uracil
  • 6-[(3-methylolphenyl)amino]uracil

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi RNase H family protein 0.0023 0.0067 0.0184
Echinococcus multilocularis thymidine phosphorylase 0.1248 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0061 0.0409
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 0.5359
Schistosoma mansoni hypothetical protein 0.0132 0.0951 0.6403
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0039 0.0262
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 1
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0118 0.1006
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0218 0.1043
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0087 0.0585 0.4597
Schistosoma mansoni hypothetical protein 0.0057 0.0343 0.2308
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0133 0.0958 0.0932
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0087 0.0585 0.599
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0218 0.0905
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0039 0.001
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.0049 0.0278 0.1193
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0029 0.0049
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0133 0.0958 0.7695
Echinococcus granulosus ribonuclease H1 0.0023 0.0067 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0061 0.0032
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0218 0.1467
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0195 0.1371
Onchocerca volvulus 0.0022 0.0061 0.0132
Echinococcus multilocularis ribonuclease H1 0.0023 0.0067 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0313 0.3059
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0061 0.0032
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0061 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0218 0.0905
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0061 0.0154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0218 0.0905
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0313 0.0285
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0278 0.025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0116 0.042
Onchocerca volvulus 0.0022 0.0061 0.0132
Entamoeba histolytica AMP deaminase, putative 0.0055 0.0324 0.2602
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0055 0.0324 0.2457
Brugia malayi AKH receptor 0.0022 0.0061 0.0154
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0133 0.0958 0.0932
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0133 0.0958 0.765
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.0168 0.1245 0.3997
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0218 0.019
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0313 0.2513
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0061 0.0032
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0061 0.0154
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0061 0.0032
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0093 0.0065
Brugia malayi MAP kinase sur-1 0.0053 0.0313 0.1359
Trypanosoma cruzi AMP deaminase 2, putative 0.0055 0.0324 0.3212
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0218 0.019
Loa Loa (eye worm) hypothetical protein 0.0113 0.08 0.3688
Echinococcus granulosus serotonin receptor 0.0022 0.0061 0.0032
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0061 0.0409
Toxoplasma gondii cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein 0.0053 0.0306 0.2457
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0218 0.0905
Schistosoma mansoni thyroid hormone receptor 0.0174 0.1289 0.8685
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0061 0.0032
Schistosoma mansoni myosin xvIII 0.0022 0.0061 0.0409
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Loa Loa (eye worm) DR-78 0.002 0.0039 0.0049
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0061 0.0409
Echinococcus granulosus lamin dm0 0.0055 0.0323 0.0295
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.101 0.4695
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0133 0.0958 1
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0117 0.0422
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0133 0.0958 0.645
Echinococcus granulosus adenosine deaminase 0.0168 0.1245 0.1219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0218 0.0905
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0039 0.001
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0313 0.2366
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0418 0.2817
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0061 0.0032
Schistosoma mansoni intermediate filament proteins 0.0055 0.0323 0.2176
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0218 0.1467
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0061 0.0154
Echinococcus granulosus g protein coupled receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0218 0.0905
Schistosoma mansoni biogenic amine receptor 0.0022 0.0061 0.0409
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0218 0.0905
Loa Loa (eye worm) hypothetical protein 0.0048 0.0265 0.1131
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0061 0.0154
Brugia malayi Serotonin receptor 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0174 0.1295 0.6054
Brugia malayi RNase H family protein 0.0023 0.0067 0.0184
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0061 0.0409
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0087 0.0585 0.601
Brugia malayi nuclear receptor RXR 0.002 0.0039 0.0049
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0118 0.0947
Trypanosoma brucei cytidine deaminase 0.0053 0.0306 0.3017
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0133 0.0958 1
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0313 0.0285
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0055 0.0324 0.3212
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0137 0.1209
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0055 0.0324 0.3212
Loa Loa (eye worm) AMP deaminase 0.0055 0.0324 0.1412
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0061 0.0032
Schistosoma mansoni lamin 0.0055 0.0323 0.2176
Loa Loa (eye worm) hypothetical protein 0.0168 0.1245 0.5815
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0137 0.1209
Giardia lamblia Cytidine deaminase 0.0053 0.0306 0.2983
Echinococcus multilocularis zinc finger protein 0.0023 0.0065 0.0036
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0116 0.0935
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0039 0.0005
Onchocerca volvulus 0.0022 0.0061 0.0132
Echinococcus multilocularis thyroid hormone receptor alpha 0.0174 0.1289 0.1264
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0039 0.001
Brugia malayi hypothetical protein 0.0077 0.0504 0.2273
Loa Loa (eye worm) hypothetical protein 0.0026 0.0093 0.031
Schistosoma mansoni jun-related protein 0.008 0.0526 0.3541
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0352 0.2736 0.2715
Onchocerca volvulus 0.0053 0.0306 0.1553
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0117 0.0422
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0218 0.1467
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1534 0.7197
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni opsin-like receptor 0.0022 0.0061 0.0409
Onchocerca volvulus 0.0022 0.0061 0.0132
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0058 0.003
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0216 0.1081
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0418 0.2817
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0133 0.0958 1
Echinococcus granulosus cytidine deaminase 0.0053 0.0306 0.0278
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0061 0.0154
Onchocerca volvulus 0.0022 0.0061 0.0132
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0087 0.0585 0.601
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0093 0.0064
Schistosoma mansoni opsin-like receptor 0.0022 0.0061 0.0409
Trypanosoma cruzi AMP deaminase, putative 0.0055 0.0324 0.3212
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0324 0.0296
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0087 0.0586 0.2664
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0074 0.0598
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0057 0.0343 0.0315
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0087 0.0586 0.0559
Brugia malayi Dopamine receptor protein 2 0.0022 0.0061 0.0154
Schistosoma mansoni zinc finger protein 0.002 0.0039 0.0262
Trypanosoma brucei RNA helicase, putative 0.0087 0.0584 0.5997
Echinococcus granulosus neuropeptide receptor 0.0022 0.0061 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0313 0.2107
Schistosoma mansoni amine GPCR 0.0022 0.0061 0.0409
Schistosoma mansoni nuclear hormone receptor 0.002 0.0039 0.0262
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0108 0.0079
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0313 0.3093
Brugia malayi adenosine monophosphate deaminase 0.0055 0.0324 0.1412
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0218 0.0905
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Onchocerca volvulus 0.0022 0.0061 0.0132
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0313 0.0285
Schistosoma mansoni hypothetical protein 0.0198 0.1485 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0218 0.019
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0418 0.2817
Brugia malayi larval opioid receptor 0.0022 0.0061 0.0154
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0118 0.1006
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0038 0.0077
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0061 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0218 0.0905
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0118 0.0735
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0058 0.0141
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0061 0.0032
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0087 0.0585 0.601
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Echinococcus granulosus RUN 0.002 0.0038 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0061 0.0409
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0218 0.019
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0113 0.08 0.3688
Trypanosoma brucei unspecified product 0.0025 0.0083 0.0632
Loa Loa (eye worm) hypothetical protein 0.0025 0.0085 0.0271
Loa Loa (eye worm) hypothetical protein 0.0027 0.01 0.034
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0061 0.0032
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 0.5359
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus neuropeptide s receptor 0.0022 0.0061 0.0032
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0061 0.0032
Schistosoma mansoni polycystin 1-related 0.002 0.0038 0.0256
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus tar DNA binding protein 0.0066 0.0418 0.0391
Leishmania major adenine aminohydrolase 0.0168 0.1245 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0061 0.0154
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0057 0.0343 0.3413
Trypanosoma brucei ingi protein (ORF1) 0.0025 0.0083 0.0632
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0116 0.0935
Brugia malayi RE15519p 0.0022 0.0061 0.0154
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0118 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0343 0.1812
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0061 0.0154
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0061 0.0154
Trypanosoma cruzi cytidine deaminase-like protein, putative 0.0053 0.0306 0.3017
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0061 0.0409
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0038 0.0009
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0116 0.042
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0352 0.2736 0.2715
Mycobacterium ulcerans thymidine phosphorylase 0.1248 1 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0324 0.1412
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0313 0.0285
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0133 0.0958 0.7695
Brugia malayi Bromodomain containing protein 0.0088 0.059 0.2683
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni AMP deaminase 0.0055 0.0324 0.2181
Brugia malayi Serotonin receptor 0.0022 0.0061 0.0154
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0061 0.0032
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0038 0.0009
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0039 0.001
Loa Loa (eye worm) hypothetical protein 0.0048 0.0272 0.1165
Brugia malayi Adenosine/AMP deaminase family protein 0.0168 0.1245 0.5815
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0098 0.0675 0.0648
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0046 0.0251 0.1283
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0058 0.0391
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0046 0.0252 0.0224
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0218 0.0905
Brugia malayi Nuclear hormone receptor E75 0.002 0.0039 0.0049
Brugia malayi RNA binding protein 0.0066 0.0418 0.1863
Echinococcus multilocularis musashi 0.0055 0.0323 0.0295
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0039 0.001
Schistosoma mansoni nuclear hormone receptor 0.002 0.0039 0.0262
Schistosoma mansoni ap endonuclease 0.0018 0.0029 0.0192
Echinococcus granulosus allatostatin A receptor 0.0022 0.0061 0.0032
Echinococcus granulosus AMP deaminase 2 0.0055 0.0324 0.0296
Brugia malayi hypothetical protein 0.002 0.0039 0.0049
Onchocerca volvulus 0.0022 0.0061 0.0132
Plasmodium falciparum AMP deaminase, putative 0.0055 0.0324 0.2429
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.212 0.2097
Loa Loa (eye worm) RecQ helicase 0.0042 0.0216 0.0896
Brugia malayi hypothetical protein 0.002 0.0038 0.0045
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0336 0.1471
Loa Loa (eye worm) hypothetical protein 0.0087 0.0586 0.2664
Onchocerca volvulus 0.0077 0.0504 0.2702
Schistosoma mansoni hypothetical protein 0.002 0.0038 0.0256
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0057 0.0343 0.3413
Plasmodium vivax adenosine/AMP deaminase, putative 0.0055 0.0324 0.2429
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0313 0.1639
Schistosoma mansoni phosphoglucomutase 0.0023 0.0067 0.0451
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0093 0.0065
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 0.5359
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0216 0.0188
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0039 0.001
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0133 0.0958 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0278 0.025
Schistosoma mansoni adenosine deaminase 0.0168 0.1245 0.8382
Echinococcus granulosus neuropeptide receptor 0.0022 0.0061 0.0032
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0218 0.019
Echinococcus multilocularis somatostatin receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Brugia malayi bZIP transcription factor family protein 0.0098 0.0675 0.309
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Brugia malayi G-protein coupled receptor 0.0022 0.0061 0.0154
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0133 0.0958 0.765
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0118 0.1006
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0061 0.0032
Onchocerca volvulus 0.0022 0.0061 0.0132
Brugia malayi nuclear hormone receptor 0.0042 0.0218 0.0905
Schistosoma mansoni DNA helicase recq1 0.0029 0.0116 0.0784
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0141
Brugia malayi G-protein coupled receptor 0.0022 0.0061 0.0154
Echinococcus granulosus fmrfamide receptor 0.0022 0.0061 0.0032
Schistosoma mansoni phosphoglucomutase 0.0023 0.0067 0.0451
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0133 0.0958 1
Trichomonas vaginalis cytidine deaminase, putative 0.0053 0.0306 0.1599
Echinococcus granulosus orexin receptor type 2 0.0022 0.0061 0.0032
Brugia malayi Doublecortin family protein 0.002 0.0038 0.0045
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0324 0.0296
Trichomonas vaginalis ribonuclease H1, putative 0.0023 0.0067 0.0222
Echinococcus granulosus geminin 0.0198 0.1485 0.146
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0133 0.0958 0.4443
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Schistosoma mansoni adenosine deaminase-related 0.0168 0.1245 0.8382
Treponema pallidum ribonuclease H (rnhA) 0.0023 0.0067 0.0316
Brugia malayi steroid hormone receptor 0.0042 0.0218 0.0905
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0418 0.1863
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni zinc finger protein 0.0023 0.0065 0.0435
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0116 0.0784
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0058 0.0141
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0061 0.0154
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Echinococcus multilocularis neuropeptide receptor A26 0.0022 0.0061 0.0032
Onchocerca volvulus 0.0022 0.0061 0.0132
Mycobacterium ulcerans adenosine deaminase 0.0168 0.1245 0.1219
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0218 0.019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Entamoeba histolytica DNA repair and recombination protein, putative 0.0057 0.0343 0.2754
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0061 0.0132
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0141
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0218 0.1043
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0218 0.019
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0272 0.1834
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0061 0.0032
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0061 0.0032
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0418 0.2817
Brugia malayi hypothetical protein 0.002 0.0038 0.0045
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0061 0.0409
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0061 0.0409
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0041 0.0012
Loa Loa (eye worm) hypothetical protein 0.0095 0.0653 0.2986
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0218 0.019
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0313 0.3093
Echinococcus multilocularis cytidine deaminase 0.0053 0.0306 0.0278
Loa Loa (eye worm) hypothetical protein 0.0113 0.08 0.3688
Echinococcus granulosus somatostatin receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0418 0.1863
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0093 0.0624
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0039 0.0049
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0061 0.0409
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0057 0.0343 0.3413
Brugia malayi G protein-coupled receptor 0.0022 0.0061 0.0154
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0041 0.0274
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0061 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Brugia malayi nuclear hormone receptor 0.002 0.0039 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus bloom syndrome protein 0.0042 0.0216 0.0188
Brugia malayi nuclear receptor NHR-88 0.0042 0.0218 0.0905
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0418 0.2817
Schistosoma mansoni hypothetical protein 0.008 0.0526 0.3541
Onchocerca volvulus Ribonuclease H1 homolog 0.0023 0.0067 0.0169
Brugia malayi ecdysteroid receptor 0.0042 0.0218 0.0905
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0218 0.0905
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0218 0.1467
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0216 0.0896
Schistosoma mansoni adenoreceptor 0.0022 0.0061 0.0409
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0039 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0313 0.1639
Onchocerca volvulus 0.0022 0.0061 0.0132
Toxoplasma gondii ribonuclease HI protein 0.0023 0.0067 0.0539
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Brugia malayi Bromodomain containing protein 0.0045 0.0242 0.102
Brugia malayi sulfakinin receptor protein 0.0022 0.0061 0.0154
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 0.5359
Schistosoma mansoni biogenic amine receptor 0.0022 0.0061 0.0409
Entamoeba histolytica AMP deaminase, putative 0.0055 0.0324 0.2602
Brugia malayi intermediate filament protein 0.0055 0.0323 0.1408
Echinococcus granulosus jun protein 0.0098 0.0675 0.0648
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 1
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0079 0.0415
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Schistosoma mansoni bromodomain containing protein 0.0074 0.0479 0.3224
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0132 0.0951 0.0925
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0141
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0137 0.11
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0041 0.0213 0.0883
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0093 0.0064
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0061 0.0409
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0133 0.0958 0.645
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Onchocerca volvulus 0.0022 0.0061 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0218 0.0905
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0061 0.0154
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0061 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0061 0.0032
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0218 0.019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Leishmania major AMP deaminase, putative 0.0055 0.0324 0.2457
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0445 0.0417
Onchocerca volvulus 0.0232 0.1762 1
Trypanosoma cruzi AMP deaminase, putative 0.0055 0.0324 0.3212
Schistosoma mansoni opsin-like receptor 0.0022 0.0061 0.0409
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0075 0.022
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0092 0.0624 0.2845
Leishmania major hypothetical protein, conserved 0.0055 0.0324 0.2457
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0061 0.0154
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0278 0.1872
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Echinococcus multilocularis tumor protein p63 0.0331 0.2565 0.2544
Echinococcus granulosus g protein coupled receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Onchocerca volvulus 0.0022 0.0061 0.0132
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.002 0.0038 0.0045
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0116 0.0088
Trypanosoma brucei ribonuclease H1 0.0023 0.0067 0.0461
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0057 0.0343 0.3413
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0218 0.019
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0061 0.0032
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0137 0.0625
Schistosoma mansoni biogenic amine receptor 0.0022 0.0061 0.0409
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0061 0.0154
Brugia malayi ORL1-like opioid receptor 0.0022 0.0061 0.0154
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0061 0.0409
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0061 0.0154
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0218 0.0905
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0168 0.1245 1
Brugia malayi Dopamine receptor 0.0022 0.0061 0.0154
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0039 0.001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0061 0.0032
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0061 0.0154
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0058 0.0391
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0218 0.1467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0141
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0352 0.2736 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0041 0.0213 0.2026
Onchocerca volvulus Adenosine deaminase homolog 0.0168 0.1245 0.6998
Entamoeba histolytica hypothetical protein, conserved 0.0057 0.0343 0.2754
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0133 0.0958 0.7641
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1762 1
Echinococcus granulosus muscleblind protein 0.0174 0.1295 0.127
Brugia malayi nuclear receptor RXR 0.0022 0.0058 0.0141
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0218 0.1467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.101 0.4695
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0061 0.0032
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0041 0.0213 0.2026
Brugia malayi ecdysone receptor 0.002 0.0039 0.0049
Schistosoma mansoni neuropeptide receptor 0.0022 0.0061 0.0409
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0116 0.0722
Schistosoma mansoni survival motor neuron protein 0.0056 0.0336 0.2264
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0133 0.0958 1
Brugia malayi Muscleblind-like protein 0.0174 0.1295 0.6054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.022 0.0192
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0038 0.0045
Loa Loa (eye worm) hypothetical protein 0.0276 0.212 1
Schistosoma mansoni ap endonuclease 0.0018 0.0029 0.0192
Schistosoma mansoni neuropeptide receptor 0.0022 0.0061 0.0409
Schistosoma mansoni nuclear receptor 0.002 0.0039 0.0262
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0061 0.0032
Brugia malayi neuropeptide F receptor 0.0022 0.0061 0.0154
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0116 0.0944
Echinococcus multilocularis geminin 0.0198 0.1485 0.146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0061 0.0032
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0061 0.0409
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0061 0.0409
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0092 0.0624 0.2845
Schistosoma mansoni amine GPCR 0.0022 0.0061 0.0409
Schistosoma mansoni loxhd1 0.002 0.0038 0.0256
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0055 0.0324 0.2457
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0087 0.0586 0.3214
Brugia malayi putative neuropeptide receptor 0.0022 0.0061 0.0154
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0055 0.0324 0.3212
Echinococcus multilocularis RUN 0.002 0.0038 0.0009
Schistosoma mansoni hypothetical protein 0.0056 0.0336 0.2264
Echinococcus granulosus lamin 0.0055 0.0323 0.0295
Schistosoma mansoni amine GPCR 0.0022 0.0061 0.0409
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0061 0.0409
Echinococcus granulosus tumor protein p63 0.0331 0.2565 0.2544
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) doublecortin family protein 0.002 0.0038 0.0045
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0045 0.0243 0.1024
Echinococcus multilocularis AMP deaminase 2 0.0055 0.0324 0.0296
Echinococcus multilocularis lamin 0.0055 0.0323 0.0295
Echinococcus multilocularis adenosine deaminase 0.0168 0.1245 0.1219
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0061 0.0409
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0168 0.1245 1
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 0.5359
Leishmania major hypothetical protein, conserved 0.0029 0.0118 0.0769
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0116 0.042
Mycobacterium leprae PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) 0.0053 0.0306 0.0218
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0218 0.1467
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0038 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0218 0.0905
Schistosoma mansoni amine GPCR 0.0022 0.0061 0.0409
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0133 0.0958 0.0932
Onchocerca volvulus 0.0055 0.0323 0.1653
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0218 0.0905
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0061 0.0032
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0313 0.2366
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0061 0.0032
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0313 0.3093
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0061 0.0154
Leishmania major cytidine deaminase-like protein 0.0053 0.0306 0.2308
Brugia malayi hypothetical protein 0.0029 0.0118 0.0427
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Trypanosoma brucei AMP deaminase, putative 0.0055 0.0324 0.3212
Schistosoma mansoni neuropeptide receptor 0.0022 0.0061 0.0409
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0038 0.0077
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0133 0.0958 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0218 0.019
Trypanosoma cruzi AMP deaminase, putative 0.0055 0.0324 0.3212
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.0174 0.1295 0.6054
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0218 0.019
Echinococcus granulosus neuropeptide receptor A26 0.0022 0.0061 0.0032
Echinococcus granulosus g protein coupled receptor 0.0022 0.0061 0.0032
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0133 0.0958 1
Plasmodium vivax adenosine deaminase, putative 0.0168 0.1245 1
Plasmodium vivax SET domain protein, putative 0.0029 0.0116 0.0722
Schistosoma mansoni hypothetical protein 0.0022 0.0061 0.0409
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0061 0.0032
Echinococcus multilocularis sex peptide receptor 0.0022 0.0061 0.0032
Schistosoma mansoni nuclear receptor 0.002 0.0039 0.0262
Schistosoma mansoni hypothetical protein 0.0087 0.0584 0.3933
Schistosoma mansoni rab6-interacting 0.002 0.0038 0.0256
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0061 0.0032
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0133 0.0958 0.645
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0039 0.001
Brugia malayi hypothetical protein 0.0276 0.212 1
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0133 0.0958 0.7641
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni hypothetical protein 0.0018 0.0024 0.0162
Onchocerca volvulus 0.0022 0.0061 0.0132
Loa Loa (eye worm) hypothetical protein 0.0055 0.0323 0.1408
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.212 0.2097
Loa Loa (eye worm) hypothetical protein 0.0029 0.0118 0.0427
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0116 0.0088
Brugia malayi nuclear receptor NHR-67 0.002 0.0039 0.0049
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0061 0.0032
Onchocerca volvulus 0.0053 0.0306 0.1553
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0039 0.0005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0132 0.0951 0.0925
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0039 0.0262
Echinococcus granulosus sex peptide receptor 0.0022 0.0061 0.0032
Onchocerca volvulus 0.0022 0.0061 0.0132
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0061 0.0409
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0087 0.0586 0.0559
Leishmania major ribonuclease H1, putative 0.0023 0.0067 0.0352
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0039 0.0049
Brugia malayi Pre-SET motif family protein 0.0029 0.0116 0.042
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0061 0.0032
Brugia malayi hypothetical protein 0.0022 0.0058 0.0141
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.022 0.0192
Loa Loa (eye worm) hypothetical protein 0.0113 0.08 0.3688
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Loa Loa (eye worm) RNA binding protein 0.0066 0.0418 0.1863
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0038 0.0009
Trichomonas vaginalis cytidine deaminase, putative 0.0053 0.0306 0.1599
Onchocerca volvulus 0.0042 0.0218 0.1043
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0061 0.0032
Onchocerca volvulus 0.0048 0.0272 0.1359
Loa Loa (eye worm) hypothetical protein 0.0054 0.0315 0.1369
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0061 0.0409
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0061 0.0032
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0133 0.0958 0.0932
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0061 0.0409
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0039 0.001
Brugia malayi Dopamine receptor protein 1 0.0022 0.0061 0.0154
Trypanosoma brucei AMP deaminase, putative 0.0055 0.0324 0.3212
Trypanosoma cruzi ribonuclease H1, putative 0.0023 0.0067 0.0461
Schistosoma mansoni hypothetical protein 0.0022 0.0061 0.0409
Echinococcus granulosus intermediate filament protein 0.0055 0.0323 0.0295
Schistosoma mansoni hypothetical protein 0.0198 0.1485 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0041 0.0012
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0905
Schistosoma mansoni thyroid hormone receptor 0.0174 0.1289 0.8685
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0218 0.019
Echinococcus multilocularis muscleblind protein 1 0.0174 0.1295 0.127
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0039 0.0049
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0061 0.0032
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0133 0.0958 0.7695
Brugia malayi conserved hypotetical protein 0.002 0.0039 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0313 0.3093
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0039 0.0049
Onchocerca volvulus 0.0055 0.0324 0.1658
Treponema pallidum adenosine deaminase 0.0168 0.1245 1
Schistosoma mansoni phosphoglucomutase 0.0023 0.0067 0.0451
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0039 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0218 0.0905
Toxoplasma gondii AMP deaminase 0.0055 0.0324 0.2602
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0323 0.1408
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0061 0.0032
Onchocerca volvulus AMP deaminase 2 homolog 0.0055 0.0324 0.1658
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0061 0.0032
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0029 0.023
Echinococcus multilocularis jun protein 0.0098 0.0675 0.0648
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0133 0.0958 0.7695
Echinococcus multilocularis neuropeptide s receptor 0.0022 0.0061 0.0032
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0023 0.0067 0.0414
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0041 0.0213 0.2026
Brugia malayi GnHR receptor homolog 0.0022 0.0061 0.0154
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0046 0.0251 0.1064
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0116 0.0088
Schistosoma mansoni neuropeptide receptor 0.0022 0.0061 0.0409
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0118 0.0735
Onchocerca volvulus 0.0022 0.0061 0.0132
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0029 0.0049
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0038 0.0009
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0218 0.1467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Onchocerca volvulus 0.002 0.0039 0.0005
Brugia malayi hypothetical protein 0.0019 0.0033 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Trichomonas vaginalis adenosine deaminase, putative 0.0168 0.1245 0.7014
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0039 0.001
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0216 0.1081
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0061 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Toxoplasma gondii exonuclease III APE 0.0018 0.0029 0.023
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0058 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0141
Brugia malayi cytidine deaminase, identical 0.0053 0.0306 0.1325
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0323 0.1408
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0061 0.0032
Brugia malayi Nuclear hormone receptor E75 0.002 0.0039 0.0049
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0116 0.0935
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0061 0.0032
Schistosoma mansoni coup transcription factor 0.0042 0.0218 0.1467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0087 0.0586 0.3214
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0061 0.0409
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0218 0.0905
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0041 0.0213 0.2026
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0061 0.0032
Echinococcus granulosus hypothetical protein 0.0022 0.0061 0.0032
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0061 0.0032
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0418 0.1863
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0313 0.1639
Schistosoma mansoni zinc finger protein 0.0018 0.0024 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0218 0.0905
Mycobacterium tuberculosis Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) 0.0053 0.0306 0.0278
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Onchocerca volvulus 0.0022 0.0061 0.0132
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0061 0.0409
Brugia malayi nuclear receptor NHR-88 0.002 0.0039 0.0049
Schistosoma mansoni amine GPCR 0.0022 0.0061 0.0409
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0061 0.0032
Giardia lamblia Ribonuclease H 0.0023 0.0067 0.0414
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0218 0.019
Echinococcus multilocularis serotonin receptor 0.0022 0.0061 0.0032
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.1248 1 1
Brugia malayi neuropeptide F receptor 0.0022 0.0061 0.0154
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0038 0.0009
Brugia malayi RNase H family protein 0.0023 0.0067 0.0184
Trypanosoma cruzi AMP deaminase, putative 0.0055 0.0324 0.3212
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0061 0.0032
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0218 0.1043
Trypanosoma brucei ingi protein (ORF1) 0.0025 0.0083 0.0632
Plasmodium falciparum adenosine deaminase 0.0168 0.1245 1
Trypanosoma cruzi cytidine deaminase-like protein 0.0053 0.0306 0.3017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0313 0.1359
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0057 0.0343 0.3413
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0218 0.1467
Onchocerca volvulus 0.0022 0.0061 0.0132
Schistosoma mansoni hypothetical protein 0.0024 0.0075 0.0502
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0061 0.0032
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0218 0.019
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0041 0.0274
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0061 0.0032
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0087 0.0586 0.2664
Schistosoma mansoni DNA helicase recq5 0.0029 0.0116 0.0784
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0133 0.0958 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Onchocerca volvulus 0.0029 0.0116 0.0455
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0083 0.0632
Trypanosoma brucei protein kinase, putative 0.0053 0.0313 0.3093
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0057 0.0343 0.2611
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0218 0.0905
Echinococcus multilocularis serotonin receptor 0.0022 0.0061 0.0032
Echinococcus multilocularis muscleblind protein 0.0174 0.1295 0.127
Brugia malayi tailless protein 0.002 0.0039 0.0049
Schistosoma mansoni histamine h1 receptor 0.0022 0.0061 0.0409
Brugia malayi PHD-finger family protein 0.0029 0.0115 0.0414
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0116 0.0088
Brugia malayi TAR-binding protein 0.0066 0.0418 0.1863
Loa Loa (eye worm) hypothetical protein 0.0083 0.0549 0.249
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0218 0.0905
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0445 0.0417
Onchocerca volvulus 0.0056 0.0336 0.1729
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0061 0.0032
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0029 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0055 0.0324 0.2457
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0095 0.064
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0041 0.0213 0.2026
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0061 0.0132
Trypanosoma brucei AMP deaminase, putative 0.0055 0.0324 0.3212
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0116 0.042
Schistosoma mansoni hypothetical protein 0.0022 0.0061 0.0409
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0039 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0313 0.1639
Onchocerca volvulus 0.0055 0.0323 0.1653
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0061 0.0154
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0133 0.0958 1
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0025 0.0083 0.0632
Trypanosoma cruzi AMP deaminase, putative 0.0055 0.0324 0.3212
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0218 0.019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0116 0.0784
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0057 0.0343 0.0315
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0039 0.0049
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0116 0.0088
Schistosoma mansoni lamin 0.0055 0.0323 0.2176
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0313 0.3093
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0061 0.0409
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0061 0.0154
Brugia malayi hypothetical protein 0.0022 0.0061 0.0154
Schistosoma mansoni lipoxygenase 0.0055 0.0324 0.2182
Schistosoma mansoni hypothetical protein 0.0022 0.0061 0.0409
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0058 0.003
Brugia malayi Melatonin receptor type 1A 0.0022 0.0061 0.0154
Loa Loa (eye worm) hypothetical protein 0.005 0.0283 0.1217
Trypanosoma cruzi ribonuclease H1, putative 0.0023 0.0067 0.0461
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Echinococcus multilocularis lamin dm0 0.0055 0.0323 0.0295
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0061 0.0154
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0323 0.1408
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0098 0.0675 0.0648
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0049
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0061 0.0032
Onchocerca volvulus 0.002 0.0039 0.0005
Brugia malayi MH2 domain containing protein 0.0139 0.101 0.4695
Trichomonas vaginalis adenosine deaminase, putative 0.0168 0.1245 0.7014
Brugia malayi hypothetical protein 0.0022 0.0058 0.0141
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0057 0.0343 0.2611
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0133 0.0958 0.7641
Mycobacterium ulcerans cytidine deaminase 0.0053 0.0306 0.0278
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0133 0.0958 0.0932
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0418 0.0391
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0039 0.001
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0061 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0218 0.019
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0061 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0039 0.001
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0137 0.0925
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0218 0.0905
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0133 0.0958 0.645
Loa Loa (eye worm) hypothetical protein 0.0025 0.0085 0.0271
Entamoeba histolytica adenosine deaminase, putative 0.0168 0.1245 1
Entamoeba histolytica cytidine deaminase, putative 0.0053 0.0306 0.2457
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0133 0.0958 0.7695
Entamoeba histolytica adenosine deaminase, putative 0.0168 0.1245 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0218 0.0905
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Brugia malayi Pre-SET motif family protein 0.0204 0.1534 0.7197
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.0168 0.1245 0.1219
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0278 0.1872
Schistosoma mansoni lipoxygenase 0.002 0.0038 0.0256
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0218 0.1467
Brugia malayi hypothetical protein 0.002 0.0039 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0061 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0218 0.0905
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0061 0.0032
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0046 0.0086
Giardia lamblia Rrm3p helicase 0.0057 0.0343 0.3381
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0061 0.0032
Schistosoma mansoni rab6-interacting 0.002 0.0038 0.0256
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0218 0.0905
Echinococcus granulosus zinc finger protein 0.0023 0.0065 0.0036

Activities

Activity type Activity value Assay description Source Reference
Degree of resistance (binding) 12.4 Degree of resistance is the ratio between inhibition of Bacillus subtilis DNA Polymerase III azp-12 and WT. ChEMBL. 6767030
Degree of resistance (binding) 12.4 Degree of resistance is the ratio between inhibition of Bacillus subtilis DNA Polymerase III azp-12 and WT. ChEMBL. 6767030
Ki (binding) = 2.29 Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme). ChEMBL. 6420570
Ki (binding) = 3.384 Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type). ChEMBL. 6420570
Ki (binding) = 413 uM Inhibition against Bacillus subtilis DNA topoisomerase III (wild type) ChEMBL. 6767030
Ki (binding) = 413 uM Inhibition against Bacillus subtilis DNA topoisomerase III (wild type) ChEMBL. 6767030
Ki (binding) = 5130 uM In vitro inhibition of Bacillus subtilis DNA Polymerase III/azp-12(mutant). ChEMBL. 6767030
Ki (binding) = 5130 uM In vitro inhibition of Bacillus subtilis DNA Polymerase III/azp-12(mutant). ChEMBL. 6767030
Log 1/Ki (binding) = 2.29 Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme). ChEMBL. 6420570
Log 1/Ki (binding) = 3.384 Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type). ChEMBL. 6420570

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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