Detailed information for compound 836889

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 383.467 | Formula: C19H21N5O2S
  • H donors: 0 H acceptors: 1 LogP: 3.01 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1N=c2sc(nn2C(=N)C1=Cc1ccc(cc1)C(C)C)N1CCOCC1
  • InChi: 1S/C19H21N5O2S/c1-12(2)14-5-3-13(4-6-14)11-15-16(20)24-18(21-17(15)25)27-19(22-24)23-7-9-26-10-8-23/h3-6,11-12,20H,7-10H2,1-2H3/b15-11+,20-16?
  • InChiKey: VQSCIPBUODPSRD-UMWCEBECSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0497 0.0646
Brugia malayi hypothetical protein 0.007 0.0632 0.2503
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0018 0.0025 0.0097
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0141 0.0559
Brugia malayi G protein-coupled receptor 0.0128 0.1305 0.5169
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni leucyl-tRNA synthetase 0.0052 0.0421 0.0547
Echinococcus granulosus valyl tRNA synthetase 0.0052 0.0421 0.0547
Brugia malayi Protein kinase c protein 2 0.0092 0.0886 0.351
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0123 0.1247 0.1246
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.017 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0077 0.0715 0.093
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.017 0.0221
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0001 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0128 0.1305 0.1696
Brugia malayi follicle stimulating hormone receptor 0.0128 0.1305 0.5169
Mycobacterium ulcerans formamidopyrimidine-DNA glycosylase 0.0274 0.2998 0.5787
Onchocerca volvulus Neuropeptide F receptor homolog 0.0128 0.1305 1
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0017 0.001 0.0042
Schistosoma mansoni coup transcription factor 0.0031 0.017 0.0221
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.017 0.0674
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0003 0.0004
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0128 0.1305 0.1696
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0017 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0077 0.0715 0.2833
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0003 0.0004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0128 0.1305 0.1696
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.001 0.0014
Trichomonas vaginalis C-MYB, putative 0.0027 0.0133 0.0868
Schistosoma mansoni leucyl-tRNA synthetase 0.0021 0.0058 0.0075
Brugia malayi nuclear receptor NHR-88 0.0031 0.017 0.0674
Onchocerca volvulus 0.0128 0.1305 1
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0141 0.0559
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Echinococcus multilocularis valyl tRNA synthetase 0.0052 0.0421 0.0547
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0052 0.0421 0.1669
Echinococcus granulosus rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0128 0.1305 0.1696
Schistosoma mansoni hypothetical protein 0.0128 0.1305 0.1696
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.017 0.0674
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.017 0.0221
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0632 0.0821
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0216 0.1412
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.017 0.0674
Echinococcus multilocularis neuropeptide receptor 0.0128 0.1305 0.1696
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0128 0.1305 0.1696
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0176 0.0486
Echinococcus multilocularis protein kinase c iota type 0.0029 0.0148 0.0193
Mycobacterium ulcerans DNA polymerase IV 0.0018 0.0025 0.0045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0226 0.0293
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0339 0.0441
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0414 0.4635 0.4635
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Onchocerca volvulus 0.0089 0.0846 0.6053
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.001 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.0128 0.1305 0.1696
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.7696 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.1174 0.2265
Echinococcus granulosus zinc finger protein 0.0019 0.0039 0.0051
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Entamoeba histolytica hypothetical protein 0.007 0.0632 0.4104
Echinococcus multilocularis dna polymerase eta 0.0018 0.0025 0.0032
Schistosoma mansoni alpha-1 adrenergic receptor 0.0128 0.1305 0.1696
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0105 0.0347
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.0233 0.2525 1
Brugia malayi isocitrate dehydrogenase 0.0031 0.0176 0.0697
Loa Loa (eye worm) hypothetical protein 0.0105 0.1036 0.4101
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0141 0.0559
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0099 0.0098
Trypanosoma cruzi valyl-tRNA synthetase, putative 0.0052 0.0421 0.042
Onchocerca volvulus 0.0128 0.1305 1
Mycobacterium tuberculosis Probable reductase 0.0105 0.1038 0.2002
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0177 0.023
Echinococcus granulosus tar DNA binding protein 0.0186 0.1979 0.2572
Schistosoma mansoni amine GPCR 0.0128 0.1305 0.1696
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.017 0.0221
Echinococcus granulosus tm gpcr rhodopsin 0.0128 0.1305 0.1696
Echinococcus granulosus rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Giardia lamblia Myb 1-like protein 0.0027 0.0135 0.0877
Echinococcus granulosus neuropeptide s receptor 0.0128 0.1305 0.1696
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.1038 0.2002
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.0013
Onchocerca volvulus 0.0128 0.1305 1
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.1036 0.1346
Plasmodium falciparum isoleucine--tRNA ligase, putative 0.0147 0.1525 0.4229
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Toxoplasma gondii thioredoxin reductase 0.0046 0.0351 0.2298
Entamoeba histolytica leucyl-tRNA synthetase, putative 0.0052 0.0421 0.2713
Echinococcus multilocularis serine:threonine protein kinase N2 0.0017 0.001 0.0014
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.2503 0.3252
Trypanosoma brucei leucyl-tRNA synthetase, putative 0.0052 0.0421 0.042
Echinococcus multilocularis neuropeptide receptor A26 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0123 0.1247 0.1246
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0141 0.0559
Echinococcus granulosus intermediate filament protein 0.0029 0.015 0.0194
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0339 0.1343
Onchocerca volvulus 0.0128 0.1305 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0179 0.071
Schistosoma mansoni biogenic amine (5HT) receptor 0.0128 0.1305 0.1696
Echinococcus granulosus dro:myosuppressin receptor 0.0128 0.1305 0.1696
Schistosoma mansoni transcription factor btf3 0.0034 0.0216 0.0281
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0032 0.0127
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni unc-13 (munc13) 0.0018 0.0026 0.0034
Trypanosoma cruzi isoleucyl-tRNA synthetase, putative 0.0147 0.1525 0.1524
Loa Loa (eye worm) hypothetical protein 0.0147 0.1525 0.6038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0133 0.1358 0.1764
Echinococcus granulosus expressed conserved protein 0.0099 0.0962 0.125
Treponema pallidum isoleucyl-tRNA synthetase 0.0147 0.1525 1
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0052 0.0421 0.2758
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0016 0.0006 0.0034
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0128 0.1305 0.1696
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0032 0.0042
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0105 0.0683
Echinococcus granulosus dna polymerase kappa 0.0018 0.0025 0.0032
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0003 0.0004
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0133 0.0868
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.2503 0.3252
Plasmodium falciparum valine--tRNA ligase, putative 0.0052 0.0421 0.1166
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0133 0.0811
Brugia malayi Dopamine receptor 0.0128 0.1305 0.5169
Echinococcus granulosus alpha 1A adrenergic receptor 0.0128 0.1305 0.1696
Echinococcus multilocularis fmrfamide receptor 0.0128 0.1305 0.1696
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.007 0.0632 0.0821
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.017 0.0221
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0202 0.0798
Trypanosoma cruzi valyl-tRNA synthetase, putative 0.0031 0.0179 0.0178
Trypanosoma brucei trypanothione reductase 0.0046 0.0351 0.035
Echinococcus multilocularis allatostatin A receptor 0.0128 0.1305 0.1696
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus multilocularis tar DNA binding protein 0.0186 0.1979 0.2572
Mycobacterium ulcerans isoleucyl-tRNA synthetase 0.0147 0.1525 0.2942
Schistosoma mansoni hypothetical protein 0.0128 0.1305 0.1696
Mycobacterium leprae PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA SYNTHETASE) (VALINE--tRNA LIGASE) (VALINE TRANSLASE) ELONGS TO CLASS-I AMI 0.0052 0.0421 0.1093
Echinococcus multilocularis serotonin receptor 0.0128 0.1305 0.1696
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0176 0.1148
Mycobacterium tuberculosis Isoleucyl-tRNA synthetase IleS 0.0095 0.0919 0.1772
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Echinococcus multilocularis somatostatin receptor 0.0128 0.1305 0.1696
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0052 0.0421 0.2758
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0123 0.1247 0.1246
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0176 0.0697
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.015 0.0593
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0128 0.1305 0.1696
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0339 0.2218
Schistosoma mansoni valine-tRNA ligase 0.0052 0.0421 0.0547
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0031 0.0177 0.0701
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.1077 0.14
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0176 0.0175
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Plasmodium vivax valine--tRNA ligase, putative 0.0052 0.0421 0.2758
Toxoplasma gondii isoleucyl-tRNA synthetase family protein 0.0147 0.1525 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0025 0.0024
Echinococcus multilocularis neuropeptide s receptor 0.0128 0.1305 0.1696
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.017 0.025
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0099 0.0394
Onchocerca volvulus 0.0128 0.1305 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0128 0.1305 0.1696
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.001 0.0014
Echinococcus granulosus g protein coupled receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0105 0.0201
Echinococcus multilocularis G protein coupled receptor 139 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0089 0.0846 0.335
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0133 0.1358 0.1764
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0018 0.0025 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Brugia malayi putative neuropeptide receptor NPR1 0.0128 0.1305 0.5169
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0031 0.0179 0.1169
Echinococcus multilocularis leucyl tRNA synthetase 0.0052 0.0421 0.0547
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0876 1 1
Toxoplasma gondii AGC kinase 0.0017 0.001 0.0062
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0128 0.1305 0.1696
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0017 0.001 0.0014
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0021 0.0058 0.037
Echinococcus granulosus neuropeptide receptor 0.0128 0.1305 0.1696
Brugia malayi Protein kinase domain containing protein 0.0017 0.001 0.0042
Brugia malayi Serotonin receptor 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0069 0.0623 0.2467
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Schistosoma mansoni biogenic amine receptor 0.0128 0.1305 0.1696
Schistosoma mansoni biogenic amine receptor 0.0128 0.1305 0.1696
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0027 0.0135 0.0877
Schistosoma mansoni neuropeptide receptor 0.0128 0.1305 0.1696
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.017 0.0674
Echinococcus multilocularis orexin receptor type 2 0.0128 0.1305 0.1696
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0133 0.0811
Leishmania major valyl-tRNA synthetase, putative 0.0052 0.0421 0.042
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0128 0.1305 0.1696
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.017 0.0674
Plasmodium falciparum leucine--tRNA ligase, putative 0.0021 0.0058 0.0157
Trichomonas vaginalis DNA polymerase eta, putative 0.0018 0.0025 0.0154
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.017 0.0674
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0216 0.1412
Schistosoma mansoni patched 1 0.0045 0.0339 0.0441
Brugia malayi Dopamine receptor protein 2 0.0128 0.1305 0.5169
Trichomonas vaginalis MYB3r3, putative 0.0027 0.0133 0.0868
Onchocerca volvulus 0.0128 0.1305 1
Schistosoma mansoni nuclear hormone receptor 0.0031 0.017 0.0221
Loa Loa (eye worm) G-protein coupled receptor 0.0128 0.1305 0.5169
Brugia malayi Valyl-tRNA synthetase 0.0052 0.0421 0.1669
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni amine GPCR 0.0128 0.1305 0.1696
Schistosoma mansoni hypothetical protein 0.002 0.0051 0.0066
Loa Loa (eye worm) neuropeptide F receptor 0.0128 0.1305 0.5169
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.017 0.0221
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0228
Schistosoma mansoni hypothetical protein 0.0033 0.0202 0.0262
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.0052 0.0421 0.1402
Schistosoma mansoni amine GPCR 0.0128 0.1305 0.1696
Brugia malayi Thioredoxin reductase 0.0046 0.0351 0.1391
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0032 0.0103
Entamoeba histolytica hypothetical protein 0.007 0.0632 0.4104
Schistosoma mansoni biogenic amine (5HT) receptor 0.0128 0.1305 0.1696
Brugia malayi Protein kinase domain containing protein 0.0017 0.001 0.0042
Loa Loa (eye worm) intermediate filament protein 0.0029 0.015 0.0593
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0017 0.001 0.0042
Schistosoma mansoni opsin-like receptor 0.0128 0.1305 0.1696
Echinococcus multilocularis sex peptide receptor 0.0128 0.1305 0.1696
Brugia malayi Dopamine receptor protein 1 0.0128 0.1305 0.5169
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0128 0.1305 0.1696
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0032 0.0031
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0128 0.1305 0.5169
Loa Loa (eye worm) blistered cuticle protein 3 0.0028 0.0141 0.0559
Echinococcus multilocularis peroxidasin 0.0028 0.0141 0.0183
Plasmodium falciparum valine--tRNA ligase, putative 0.0052 0.0421 0.1166
Entamoeba histolytica deoxycytidyl transferase, putative 0.0018 0.0025 0.0093
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0032 0.0031
Echinococcus granulosus orexin receptor type 2 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.017 0.0221
Echinococcus multilocularis neuropeptides capa receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0339 0.0441
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.017 0.0674
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Echinococcus granulosus sex peptide receptor 0.0128 0.1305 0.1696
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.001 0.0013
Plasmodium falciparum leucine--tRNA ligase, putative 0.0052 0.0421 0.1166
Loa Loa (eye worm) AGC/PKN protein kinase 0.0017 0.001 0.0042
Echinococcus multilocularis g protein coupled receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0186 0.1979 0.7839
Entamoeba histolytica hypothetical protein 0.0034 0.0216 0.1358
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.017 0.0674
Brugia malayi ecdysteroid receptor 0.0031 0.017 0.0674
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0176 0.0175
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0216 0.0215
Echinococcus multilocularis serine threonine protein kinase 0.0097 0.0939 0.122
Echinococcus multilocularis valyl tRNA synthetase 0.0052 0.0421 0.0547
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0176 0.0338
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0011
Trypanosoma cruzi leucyl-tRNA synthetase, putative 0.0052 0.0421 0.042
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0003 0.0011
Echinococcus granulosus Niemann Pick C1 protein 0.015 0.1559 0.2026
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0105 0.0289
Wolbachia endosymbiont of Brugia malayi formamidopyrimidine-DNA glycosylase 0.0274 0.2998 1
Plasmodium vivax isoleucine--tRNA ligase, putative 0.0147 0.1525 1
Echinococcus multilocularis leucyl tRNA synthetase 0.0052 0.0421 0.0547
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0128 0.1305 0.1696
Schistosoma mansoni leucyl-tRNA synthetase 0.0021 0.0058 0.0075
Echinococcus granulosus serine:threonine protein kinase N2 0.0017 0.001 0.0014
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0141 0.0559
Schistosoma mansoni isoleucine--tRNA ligase 0.0147 0.1525 0.1981
Echinococcus multilocularis neuropeptide receptor 0.0128 0.1305 0.1696
Echinococcus granulosus leucyl tRNA synthetase 0.0052 0.0421 0.0547
Echinococcus multilocularis lamin dm0 0.0029 0.015 0.0194
Echinococcus granulosus transcription factor btf3 0.0034 0.0216 0.0281
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0141 0.0559
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.007
Schistosoma mansoni voltage-gated potassium channel 0.0087 0.0832 0.1081
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0176 0.1148
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni serine/threonine kinase 0.0017 0.001 0.0014
Onchocerca volvulus 0.0052 0.0421 0.2407
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0017 0.001 0.0014
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0084 0.0787 0.1023
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.017 0.0674
Chlamydia trachomatis valine--tRNA ligase 0.0052 0.0421 0.2758
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0133 0.0868
Echinococcus granulosus valyl tRNA synthetase 0.0052 0.0421 0.0547
Brugia malayi Melatonin receptor type 1A 0.0128 0.1305 0.5169
Brugia malayi intermediate filament protein 0.0029 0.015 0.0593
Schistosoma mansoni tar DNA-binding protein 0.0186 0.1979 0.2572
Loa Loa (eye worm) hypothetical protein 0.0028 0.0144 0.0568
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0128 0.1305 0.1696
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0133 0.1358 0.1764
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0032 0.0203
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Entamoeba histolytica hypothetical protein 0.007 0.0632 0.4104
Mycobacterium ulcerans valyl-tRNA synthetase 0.0052 0.0421 0.0812
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Brugia malayi ImpB/MucB/SamB family protein 0.0018 0.0025 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.001 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0128 0.1305 0.1696
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0018 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus granulosus g protein coupled receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0128 0.1305 0.1696
Brugia malayi G-protein coupled receptor 0.0128 0.1305 0.5169
Toxoplasma gondii exonuclease III APE 0.0019 0.0032 0.0203
Mycobacterium tuberculosis Conserved hypothetical protein 0.0461 0.518 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Schistosoma mansoni ap endonuclease 0.0019 0.0032 0.0042
Echinococcus granulosus neuropeptides capa receptor 0.0128 0.1305 0.1696
Schistosoma mansoni lamin 0.0029 0.015 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Trypanosoma cruzi leucyl-tRNA synthetase, putative 0.0021 0.0058 0.0056
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0032 0.0203
Echinococcus granulosus hypothetical protein 0.0128 0.1305 0.1696
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0128 0.1305 0.1696
Toxoplasma gondii Isoleucine-tRNA ligase 0.0021 0.0058 0.037
Brugia malayi sulfakinin receptor protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0351 0.2298
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0128 0.1305 0.1696
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0128 0.1305 0.1696
Brugia malayi Hr1 repeat family protein 0.0017 0.001 0.0042
Echinococcus multilocularis Niemann Pick C1 protein 0.015 0.1559 0.2026
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0073 0.0095
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0228
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.017 0.025
Schistosoma mansoni valine-tRNA ligase 0.0052 0.0421 0.0547
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0003 0.0011
Schistosoma mansoni neuropeptide receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Mycobacterium ulcerans DNA polymerase IV 0.0018 0.0025 0.0045
Schistosoma mansoni hypothetical protein 0.0043 0.032 0.0416
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Giardia lamblia Isoleucyl-tRNA synthetase 0.0147 0.1525 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis dna polymerase kappa 0.0018 0.0025 0.0032
Echinococcus granulosus serotonin receptor 0.0128 0.1305 0.1696
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0876 1 1
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.7696 1
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0017 0.001 0.0042
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0846 0.1099
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0105 0.0201
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.038 0.1506
Onchocerca volvulus 0.0128 0.1305 1
Loa Loa (eye worm) AGC/NDR protein kinase 0.0017 0.001 0.0042
Trichomonas vaginalis MYB, putative 0.0027 0.0135 0.0878
Echinococcus granulosus rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.017 0.0221
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.1038 0.2002
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0846 0.335
Schistosoma mansoni bromodomain containing protein 0.0062 0.0538 0.0699
Echinococcus granulosus rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.017 0.0674
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.1561 0.156
Brugia malayi beta-NAC-like protein 0.0034 0.0216 0.0856
Schistosoma mansoni adenoreceptor 0.0128 0.1305 0.1696
Echinococcus granulosus FTZ F1 alpha 0.0031 0.017 0.0221
Echinococcus multilocularis zinc finger protein 0.0019 0.0039 0.0051
Echinococcus granulosus lamin dm0 0.0029 0.015 0.0194
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.017 0.0221
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0133 0.1358 0.1764
Brugia malayi Bromodomain containing protein 0.0074 0.0672 0.2661
Onchocerca volvulus 0.0031 0.017 0.025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0133 0.1358 0.5378
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0032 0.0203
Loa Loa (eye worm) transcription factor SMAD2 0.0233 0.2525 1
Brugia malayi putative neuropeptide receptor 0.0128 0.1305 0.5169
Brugia malayi hypothetical protein 0.0231 0.2503 0.9911
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0128 0.1305 0.1696
Mycobacterium tuberculosis Possible DNA glycosylase 0.0274 0.2998 0.5787
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0141 0.0559
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0099 0.0394
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0017 0.0068
Onchocerca volvulus 0.0128 0.1305 1
Toxoplasma gondii valyl-tRNA synthetase 0.0052 0.0421 0.2758
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.004
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0099 0.0394
Loa Loa (eye worm) glutathione reductase 0.0046 0.0351 0.1391
Schistosoma mansoni survival motor neuron protein 0.0047 0.0363 0.0472
Loa Loa (eye worm) hypothetical protein 0.004 0.0281 0.1111
Brugia malayi isoleucyl-tRNA synthetase family protein 0.0147 0.1525 0.6038
Brugia malayi Blistered cuticle protein 3 0.0028 0.0141 0.0559
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0351 0.1391
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0128 0.1305 0.5169
Echinococcus multilocularis g protein coupled receptor 0.0128 0.1305 0.1696
Schistosoma mansoni atypical protein kinase C 0.0029 0.0148 0.0193
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus multilocularis G-protein coupled receptor, putative 0.0128 0.1305 0.1696
Echinococcus granulosus neuropeptide Y receptor 0.0128 0.1305 0.1696
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0032 0.006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0226 0.0293
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0128 0.1305 0.1696
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.017 0.0674
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.017 0.0221
Entamoeba histolytica valyl-tRNA synthetase, putative 0.0052 0.0421 0.2713
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.1038 0.2002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0128 0.1305 0.5169
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0018 0.0025 0.0024
Echinococcus granulosus NDR protein kinase 0.0017 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.017 0.0674
Leishmania major trypanothione reductase 0.0046 0.0351 0.035
Chlamydia trachomatis methionine--tRNA ligase 0.0031 0.0179 0.1169
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0073 0.0095
Loa Loa (eye worm) G-protein coupled receptor 0.0128 0.1305 0.5169
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0049 0.038 0.1506
Brugia malayi Cytochrome P450 family protein 0.0024 0.0099 0.0394
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.017 0.0221
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0128 0.1305 0.1696
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.1036 0.1346
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.001 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0087 0.0832 0.1081
Mycobacterium ulcerans hypothetical protein 0.0461 0.518 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.017 0.0674
Schistosoma mansoni neuropeptide receptor 0.0128 0.1305 0.1696
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0133 0.1358 0.5378
Echinococcus granulosus geminin 0.0498 0.5604 0.7282
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0021 0.0058 0.037
Chlamydia trachomatis isoleucine--tRNA ligase 0.0147 0.1525 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.017 0.0221
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0133 0.0811
Onchocerca volvulus 0.0031 0.0179 0.0327
Schistosoma mansoni thyroid hormone receptor 0.0031 0.017 0.0221
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0105 0.0201
Schistosoma mansoni growth hormone secretagogue receptor 0.0128 0.1305 0.1696
Schistosoma mansoni ap endonuclease 0.0019 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.017 0.0674
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0017 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.008 0.0748 0.2963
Leishmania major isoleucyl-tRNA synthetase, putative 0.0147 0.1525 0.1524
Schistosoma mansoni tar DNA-binding protein 0.0186 0.1979 0.2572
Schistosoma mansoni thyroid hormone receptor 0.0031 0.017 0.0221
Mycobacterium tuberculosis Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA glycosylase) 0.0274 0.2998 0.5787
Brugia malayi Tachykinin-like peptides receptor 99D 0.0128 0.1305 0.5169
Schistosoma mansoni lamin 0.0029 0.015 0.0194
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.017 0.0221
Schistosoma mansoni biogenic amine receptor 0.0128 0.1305 0.1696
Brugia malayi neuropeptide F receptor 0.0128 0.1305 0.5169
Brugia malayi hypothetical protein 0.0028 0.0141 0.0559
Brugia malayi Serotonin receptor 0.0128 0.1305 0.5169
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0099 0.019
Schistosoma mansoni peroxidasin 0.0028 0.0141 0.0183
Schistosoma mansoni neuropeptide receptor 0.0128 0.1305 0.1696
Echinococcus multilocularis protein patched 0.0045 0.0339 0.0441
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0032 0.0203
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0087 0.0832 0.3294
Loa Loa (eye worm) hypothetical protein 0.0038 0.0254 0.1004
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0128 0.1305 0.5169
Onchocerca volvulus 0.0128 0.1305 1
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0141 0.0559
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0351 0.0456
Onchocerca volvulus 0.0128 0.1305 1
Onchocerca volvulus 0.0128 0.1305 1
Mycobacterium leprae isoleucyl-tRNA synthetase IleS 0.0147 0.1525 0.4907
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.017 0.0221
Loa Loa (eye worm) hypothetical protein 0.0042 0.0302 0.1198
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0128 0.1305 1
Trichomonas vaginalis C-MYB, putative 0.0027 0.0133 0.0868
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.1174 0.3695
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0017 0.001 0.0014
Trypanosoma brucei unspecified product 0.0018 0.0025 0.0024
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0105 0.0683
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0351 0.0456
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Onchocerca volvulus 0.0029 0.015 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Brugia malayi Bromodomain containing protein 0.0038 0.0253 0.1001
Schistosoma mansoni neuropeptide F-like receptor 0.0128 0.1305 0.1696
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0087 0.0832 0.1081
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0087 0.0832 0.3294
Loa Loa (eye worm) TAR-binding protein 0.0186 0.1979 0.7839
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0176 0.0229
Trichomonas vaginalis isoleucyl tRNA synthetase, putative 0.0147 0.1525 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0128 0.1305 0.1696
Echinococcus granulosus tm gpcr rhodopsin 0.0128 0.1305 0.1696
Echinococcus multilocularis neuropeptide Y receptor 0.0128 0.1305 0.1696
Brugia malayi protein ZK524.3 0.0021 0.0058 0.0228
Toxoplasma gondii leucyl-tRNA synthetase 0.0052 0.0421 0.2758
Loa Loa (eye worm) hypothetical protein 0.0029 0.015 0.0593
Echinococcus multilocularis geminin 0.0498 0.5604 0.7282
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.017 0.0674
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0229
Echinococcus granulosus rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Echinococcus granulosus fmrfamide receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0011
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0018 0.0025 0.0032
Echinococcus granulosus neuropeptide FF receptor 2 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0228
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0176 0.0229
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus granulosus neuropeptide receptor A26 0.0128 0.1305 0.1696
Trypanosoma brucei DNA polymerase eta, putative 0.0018 0.0025 0.0024
Trichomonas vaginalis MYB72, putative 0.0027 0.0133 0.0868
Loa Loa (eye worm) melatonin receptor type 1A 0.0128 0.1305 0.5169
Brugia malayi CHE-14 protein 0.0045 0.0339 0.1343
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0229
Mycobacterium leprae Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA GLYCOSYLASE) 0.0274 0.2998 1
Echinococcus multilocularis RNA directed DNA polymerase 0.0077 0.0715 0.093
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0229
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Loa Loa (eye worm) VRS-2 protein 0.0021 0.0058 0.0228
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.017 0.0674
Trypanosoma brucei DNA polymerase IV, putative 0.0018 0.0025 0.0024
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0339 0.0441
Leishmania major DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Plasmodium vivax valine--tRNA ligase, putative 0.0021 0.0058 0.037
Schistosoma mansoni hypothetical protein 0.0498 0.5604 0.7282
Schistosoma mansoni intermediate filament proteins 0.0029 0.015 0.0194
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0216 0.0856
Onchocerca volvulus 0.0128 0.1305 1
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0135 0.0878
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0105 0.0683
Brugia malayi MH2 domain containing protein 0.0233 0.2525 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0128 0.1305 0.5169
Echinococcus granulosus neuropeptides capa receptor 0.0128 0.1305 0.1696
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0105 0.1036 0.677
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0032 0.0142
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0133 0.0868
Onchocerca volvulus 0.0116 0.1161 0.876
Onchocerca volvulus 0.0029 0.015 0.0072
Echinococcus multilocularis isoleucyl tRNA synthetase, cytoplasmic 0.0147 0.1525 0.1981
Schistosoma mansoni hypothetical protein 0.0043 0.032 0.0416
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0123 0.1247 0.1246
Trypanosoma brucei isoleucyl-tRNA synthetase, putative 0.0147 0.1525 0.1524
Mycobacterium ulcerans formamidopyrimidine-DNA glycosylase 0.0274 0.2998 0.5787
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.017 0.0221
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0414 0.4635 0.4635
Schistosoma mansoni amine GPCR 0.0128 0.1305 0.1696
Giardia lamblia DINP protein human, muc B family 0.0018 0.0025 0.0154
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0128 0.1305 0.1696
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.1174 0.2265
Brugia malayi RNA recognition motif domain containing protein 0.0186 0.1979 0.7839
Echinococcus granulosus microtubule associated protein 2 0.0677 0.7696 1
Plasmodium falciparum thioredoxin reductase 0.0046 0.0351 0.0972
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0133 0.0868
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.017 0.0674
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0176 0.0175
Plasmodium falciparum glutathione reductase 0.0046 0.0351 0.0972
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0051 0.0202
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0363 0.1439
Brugia malayi RNA binding protein 0.0186 0.1979 0.7839
Onchocerca volvulus 0.0128 0.1305 1
Leishmania major basic transcription factor 3a, putative 0.0034 0.0216 0.0215
Brugia malayi nuclear receptor RXR 0.0016 0.0003 0.0011
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.017 0.0674
Trichomonas vaginalis pc-MYB2, putative 0.0027 0.0133 0.0868
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni hypothetical protein 0.0043 0.032 0.0416
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.1077 0.14
Onchocerca volvulus 0.0047 0.0363 0.1909
Echinococcus multilocularis serine:threonine protein kinase N2 0.0017 0.001 0.0014
Brugia malayi RE15519p 0.0128 0.1305 0.5169
Echinococcus granulosus biogenic amine 5HT receptor 0.0128 0.1305 0.1696
Toxoplasma gondii tRNA synthetase, putative 0.0052 0.0421 0.2758
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0011
Echinococcus granulosus protein kinase C gamma type 0.0097 0.0939 0.122
Brugia malayi protein kinase C II. 0.0031 0.0177 0.0701
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0105 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.017 0.0674
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0133 0.0811
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Loa Loa (eye worm) AGC/AKT protein kinase 0.0017 0.001 0.0042
Trypanosoma brucei valyl-tRNA synthetase, putative 0.0052 0.0421 0.042
Brugia malayi glutathione reductase 0.0046 0.0351 0.1391
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.017 0.0221
Schistosoma mansoni hypothetical protein 0.0498 0.5604 0.7282
Schistosoma mansoni opsin-like receptor 0.0128 0.1305 0.1696
Schistosoma mansoni amine GPCR 0.0128 0.1305 0.1696
Echinococcus granulosus somatostatin receptor 0.0128 0.1305 0.1696
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0128 0.1305 0.1696
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0414 0.4635 0.4635
Brugia malayi leucyl-tRNA synthetase 0.0052 0.0421 0.1669
Brugia malayi nuclear hormone receptor 0.0031 0.017 0.0674
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0021 0.0058 0.037
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0351 0.0676
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.017 0.0221
Schistosoma mansoni hypothetical protein 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.017 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.017 0.0674
Brugia malayi G protein-coupled receptor F59B2.13 0.0128 0.1305 0.5169
Echinococcus multilocularis transcription factor btf3 0.0034 0.0216 0.0281
Trichomonas vaginalis pc-MYB2, putative 0.0027 0.0133 0.0868
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0674
Loa Loa (eye worm) hypothetical protein 0.0033 0.0202 0.0798
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0133 0.1358 0.1764
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.017 0.0221
Loa Loa (eye worm) hypothetical protein 0.0116 0.1161 0.4598
Entamoeba histolytica hypothetical protein 0.007 0.0632 0.4104
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.1055 0.137
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Brugia malayi valyl-tRNA synthetase family protein 0.0052 0.0421 0.1669
Onchocerca volvulus 0.0128 0.1305 1
Echinococcus multilocularis musashi 0.0029 0.015 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Entamoeba histolytica hypothetical protein 0.0025 0.0105 0.0625
Echinococcus granulosus allatostatin A receptor 0.0128 0.1305 0.1696
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.015 0.0593
Onchocerca volvulus 0.0128 0.1305 1
Echinococcus granulosus protein kinase c epsilon type 0.0031 0.0177 0.023
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0032 0.0086
Trypanosoma brucei rac serine-threonine kinase, putative 0.0017 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Echinococcus multilocularis g-protein coupled receptor 0.0128 0.1305 0.1696
Schistosoma mansoni tar DNA-binding protein 0.0186 0.1979 0.2572
Plasmodium falciparum isoleucine--tRNA ligase, putative 0.0326 0.3604 1
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0135 0.0878
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0133 0.1358 0.1764
Loa Loa (eye worm) RNA binding protein 0.0186 0.1979 0.7839
Echinococcus multilocularis dro:myosuppressin receptor 0.0128 0.1305 0.1696
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0632 0.0821
Schistosoma mansoni isoleucine--tRNA ligase 0.0147 0.1525 0.1981
Echinococcus granulosus isoleucyl tRNA synthetase, cytoplasmic 0.0147 0.1525 0.1981
Onchocerca volvulus 0.0128 0.1305 1
Echinococcus granulosus Protein kinase C brain isozyme 0.0108 0.1077 0.14
Giardia lamblia Leucyl-tRNA synthetase 0.0021 0.0058 0.037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0179 0.071
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.001 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0216 0.1412
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0073 0.0095
Echinococcus granulosus peptide allatostatin:somatostatin 0.0128 0.1305 0.1696
Brugia malayi isoleucyl-tRNA synthetase 0.0147 0.1525 0.6038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0128 0.1305 0.1696
Echinococcus granulosus g-protein coupled receptor 0.0128 0.1305 0.1696
Schistosoma mansoni hypothetical protein 0.0128 0.1305 0.1696
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0216 0.0215
Schistosoma mansoni tar DNA-binding protein 0.0186 0.1979 0.2572
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0105 0.0683
Wolbachia endosymbiont of Brugia malayi isoleucyl-tRNA synthetase 0.0147 0.1525 0.5084
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.017 0.0221
Brugia malayi PHD-finger family protein 0.0024 0.01 0.0395
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Mycobacterium tuberculosis Probable valyl-tRNA synthase protein ValS (valyl-tRNA synthetase) (valine--tRNA ligase) (valine translase) 0.0052 0.0421 0.0812
Echinococcus granulosus neuropeptide receptor 0.0128 0.1305 0.1696
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0001 0.0001
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0021 0.0058 0.037
Echinococcus granulosus leucyl tRNA synthetase 0.0052 0.0421 0.0547
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0128 0.1305 0.1696
Entamoeba histolytica valyl tRNA synthetase, putative 0.0052 0.0421 0.2713
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.0013
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0176 0.0175
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.017 0.0221
Echinococcus granulosus g protein coupled receptor 0.0128 0.1305 0.1696
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0176 0.1148
Treponema pallidum leucyl-tRNA synthetase 0.0031 0.0179 0.1169
Echinococcus granulosus G protein coupled receptor 139 0.0128 0.1305 0.1696
Schistosoma mansoni methionine-tRNA synthetase 0.0031 0.0179 0.0233
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0128 0.1305 0.5169
Echinococcus multilocularis serine:threonine protein kinase 38 0.0017 0.001 0.0014
Echinococcus granulosus potassium voltage gated channel protein 0.0087 0.0832 0.1081
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0097
Schistosoma mansoni histamine h1 receptor 0.0128 0.1305 0.1696
Trypanosoma brucei DNA polymerase IV, putative 0.0018 0.0025 0.0024
Echinococcus multilocularis potassium voltage gated channel protein 0.0087 0.0832 0.1081
Loa Loa (eye worm) neuropeptide F receptor 0.0128 0.1305 0.5169
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0027 0.0133 0.0811
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0128 0.1305 0.1696
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0497 0.0646
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0133 0.1358 0.1764
Brugia malayi p70 ribosomal S6 kinase beta 0.0017 0.001 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.017 0.0674
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.001 0.0014
Leishmania major cytochrome p450-like protein 0.0024 0.0099 0.0098
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0128 0.1305 0.1696
Brugia malayi hypothetical protein 0.0016 0.0003 0.0011
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0141 0.0559
Loa Loa (eye worm) hypothetical protein 0.0028 0.0141 0.0559
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.017 0.025
Echinococcus multilocularis expressed conserved protein 0.0099 0.0962 0.125
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0133 0.0868
Echinococcus multilocularis fmrfamide receptor 0.0128 0.1305 0.1696
Echinococcus granulosus RNA directed DNA polymerase 0.0077 0.0715 0.093
Echinococcus granulosus isoleucyl trna synthetase mitochondrial 0.0116 0.1161 0.1508
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0216 0.1412
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0027 0.0133 0.0868
Schistosoma mansoni neuropeptide F-like receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0003 0.0011
Leishmania major DNA polymerase eta, putative 0.0018 0.0025 0.0024
Echinococcus granulosus tachykinin peptides receptor 99D 0.0128 0.1305 0.1696
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0031 0.0179 0.0233
Schistosoma mansoni opsin-like receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0128 0.1305 0.5169
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Echinococcus granulosus 7TM GPCR rhodopsin 0.0128 0.1305 0.1696
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.1038 0.3224
Brugia malayi Niemann-Pick C1 protein precursor 0.0105 0.1036 0.4101
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0017 0.001 0.0042
Brugia malayi steroid hormone receptor 0.0031 0.017 0.0674
Schistosoma mansoni zinc finger protein 0.0019 0.0039 0.0051
Echinococcus granulosus dna polymerase eta 0.0018 0.0025 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.017 0.0674
Loa Loa (eye worm) hypothetical protein 0.0231 0.2503 0.9911
Brugia malayi GnHR receptor homolog 0.0128 0.1305 0.5169
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Echinococcus granulosus 7tm_1 domain containing protein 0.0128 0.1305 0.1696
Echinococcus multilocularis neuropeptides capa receptor 0.0128 0.1305 0.1696
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0632 0.0821
Echinococcus granulosus protein kinase c iota type 0.0029 0.0148 0.0193
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0846 0.1099
Entamoeba histolytica isoleucyl-tRNA synthetase, putative 0.0147 0.1525 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0853 0.3379
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.017 0.0221
Brugia malayi Cytochrome P450 family protein 0.0024 0.0099 0.0394
Schistosoma mansoni DNA polymerase eta 0.0018 0.0025 0.0032
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0018 0.0025 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Echinococcus multilocularis protein dispatched 1 0.0051 0.0413 0.0537
Toxoplasma gondii leucyl-tRNA synthetase (LeuRS2) 0.0052 0.0421 0.2758
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0176 0.0697
Loa Loa (eye worm) TYRA-2 protein 0.0128 0.1305 0.5169
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0128 0.1305 0.1696
Echinococcus multilocularis g protein coupled receptor 0.0128 0.1305 0.1696
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0031 0.0179 0.1169
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0176 0.0229
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) isoleucyl-tRNA synthetase 0.0147 0.1525 0.6038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.001 0.0013
Brugia malayi larval opioid receptor 0.0128 0.1305 0.5169
Loa Loa (eye worm) hypothetical protein 0.0055 0.0457 0.1809
Schistosoma mansoni neuropeptide f receptor 76f 0.0128 0.1305 0.1696
Giardia lamblia Valine-tRNA ligase 0.0052 0.0421 0.2758
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0421 0.2758
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0032 0.0127
Echinococcus multilocularis protein kinase c epsilon type 0.0031 0.0177 0.023
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0876 1 1
Brugia malayi G-protein coupled receptor 0.0128 0.1305 0.5169
Treponema pallidum valyl-tRNA synthetase 0.0052 0.0421 0.2758
Plasmodium vivax glutathione reductase, putative 0.0046 0.0351 0.2298
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.017 0.0221
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0031 0.0179 0.1169
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0105 0.0683
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.017 0.0674
Loa Loa (eye worm) hypothetical protein 0.0045 0.0339 0.1343
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0216 0.0597
Echinococcus multilocularis serotonin receptor 0.0128 0.1305 0.1696
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0042
Brugia malayi AKH receptor 0.0128 0.1305 0.5169
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0025 0.0045
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Echinococcus granulosus tm gpcr rhodopsin 0.0128 0.1305 0.1696
Brugia malayi Peroxidasin 0.0028 0.0141 0.0559
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.017 0.0221
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0216 0.1358
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0108 0.1077 0.14
Onchocerca volvulus 0.0128 0.1305 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0128 0.1305 0.5169
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0229
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0105 0.0104
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0031 0.0179 0.0233
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.1038 0.2002
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0099 0.0098
Brugia malayi ImpB/MucB/SamB family protein 0.0018 0.0025 0.0097
Echinococcus granulosus neuropeptide Y receptor 0.0128 0.1305 0.1696
Brugia malayi ORL1-like opioid receptor 0.0128 0.1305 0.5169
Leishmania major leucyl-tRNA synthetase, putative 0.0052 0.0421 0.042
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0351 0.035
Echinococcus granulosus peroxidasin 0.0028 0.0141 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0017 0.001 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0032 0.0031
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.017 0.0221
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.038 0.1506
Brugia malayi Protein kinase domain containing protein 0.0017 0.001 0.0042
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0021 0.0058 0.037
Brugia malayi TAR-binding protein 0.0186 0.1979 0.7839
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0216 0.0215
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0018 0.0025 0.0045
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0099 0.0098
Brugia malayi hypothetical protein 0.0016 0.0003 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0216 0.1412
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.1174 0.2265
Schistosoma mansoni peroxidasin 0.0028 0.0141 0.0183
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0032 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0025 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.017 0.0674
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0846 0.1099
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.017 0.0221
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.1038 0.2002
Schistosoma mansoni hypothetical protein 0.0047 0.0363 0.0472
Echinococcus multilocularis neuropeptide FF receptor 2 0.0128 0.1305 0.1696
Echinococcus multilocularis isoleucyl tRNA synthetase, mitochondrial 0.0116 0.1161 0.1508
Mycobacterium ulcerans leucyl-tRNA synthetase 0.0031 0.0179 0.0344
Chlamydia trachomatis leucine--tRNA ligase 0.0031 0.0179 0.1169
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.038 0.1506
Wolbachia endosymbiont of Brugia malayi valyl-tRNA synthetase 0.0052 0.0421 0.1402
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0176 0.0175
Toxoplasma gondii hypothetical protein 0.0141 0.1458 0.9562
Loa Loa (eye worm) hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni terminal deoxycytidyl transferase 0.0018 0.0025 0.0032
Schistosoma mansoni myosin xvIII 0.0128 0.1305 0.1696
Echinococcus granulosus lamin 0.0029 0.015 0.0194
Echinococcus multilocularis lamin 0.0029 0.015 0.0194
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0017 0.001 0.0014
Schistosoma mansoni hypothetical protein 0.0043 0.032 0.0416
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0128 0.1305 0.1696
Echinococcus granulosus rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Brugia malayi hypothetical protein 0.0128 0.1305 0.5169
Schistosoma mansoni tar DNA-binding protein 0.0186 0.1979 0.2572
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0032 0.0203
Toxoplasma gondii isoleucyl-tRNA synthetase, putative 0.0052 0.0421 0.2758
Echinococcus granulosus rhodopsin orphan GPCR 0.0128 0.1305 0.1696
Trypanosoma cruzi valyl-tRNA synthetase, putative 0.0021 0.0058 0.0056
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0011
Brugia malayi neuropeptide F receptor 0.0128 0.1305 0.5169
Trypanosoma brucei DNA polymerase IV, putative 0.0018 0.0025 0.0024

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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