Detailed information for compound 848687

Basic information

Technical information
  • TDR Targets ID: 848687
  • Name: 2-[(4-fluorophenyl)methyl]-4-[4-(2-fluorophen yl)piperazine-1-carbonyl]-3-(4-methoxyphenyl) -3,4-dihydroisoquinolin-1-one
  • MW: 567.625 | Formula: C34H31F2N3O3
  • H donors: 0 H acceptors: 2 LogP: 5.37 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1)C1N(Cc2ccc(cc2)F)C(=O)c2c(C1C(=O)N1CCN(CC1)c1ccccc1F)cccc2
  • InChi: 1S/C34H31F2N3O3/c1-42-26-16-12-24(13-17-26)32-31(34(41)38-20-18-37(19-21-38)30-9-5-4-8-29(30)36)27-6-2-3-7-28(27)33(40)39(32)22-23-10-14-25(35)15-11-23/h2-17,31-32H,18-22H2,1H3
  • InChiKey: VOVKGZISBKLVED-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(4-fluorophenyl)methyl]-4-[[4-(2-fluorophenyl)-1-piperazinyl]-oxomethyl]-3-(4-methoxyphenyl)-3,4-dihydroisoquinolin-1-one
  • 2-(4-fluorobenzyl)-4-[4-(2-fluorophenyl)piperazine-1-carbonyl]-3-(4-methoxyphenyl)-3,4-dihydroisocarbostyril
  • 2-[(4-fluorophenyl)methyl]-4-[4-(2-fluorophenyl)piperazin-1-yl]carbonyl-3-(4-methoxyphenyl)-3,4-dihydroisoquinolin-1-one
  • EU-0088155

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0399 0.2259 0.5848
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0272 0.4455
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0055 0.0247 0.471
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0003 0.0008
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0091 0.0457 0.1182
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0552 0.3158 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0135 0.0437
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0355 0.2225
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0101 0.0518 0.1553
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.04 0.1035
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0052 0.006
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0065 0.0209
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0021 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0578 0.0578
Entamoeba histolytica hypothetical protein 0.0026 0.008 0.0499
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0235 0.0235
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0066 0.0184
Echinococcus granulosus bloom syndrome protein 0.0044 0.0184 0.0477
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0235 0.0609
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0261 0.0676
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0066 0.107
Echinococcus granulosus voltage dependent calcium channel 0.002 0.004 0.0104
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.087 0.2831
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0033 0.0103
Schistosoma mansoni kinase 0.0047 0.0199 0.0514
Trypanosoma brucei DNA polymerase kappa, putative 0.0097 0.0492 0.1437
Schistosoma mansoni patched 1 0.0048 0.0205 0.0529
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0089 0.0253
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0204 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0184 0.0597
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.011 0.1789
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0015 0.0034
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0094 0.0474 0.1224
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0089 0.0232
Brugia malayi hypothetical protein 0.0041 0.0164 0.0531
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0355 0.1032
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0464 0.151
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0095 0.048 0.9511
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.049 0.049
Loa Loa (eye worm) hypothetical protein 0.0059 0.0268 0.0872
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0095 0.048 0.1432
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.0262
Schistosoma mansoni DNA helicase recq1 0.0018 0.0032 0.0081
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0503 0.1637
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0045
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0034 0.0126 0.0327
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0099 0.0505 0.1642
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.009 0.0453 0.0453
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0033 0.063
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0128 0.2081
Onchocerca volvulus 0.0061 0.028 0.1137
Schistosoma mansoni importin beta-1 0.0033 0.0117 0.0299
Echinococcus granulosus chromobox protein 1 0.0079 0.0387 0.1002
Loa Loa (eye worm) hypothetical protein 0.0067 0.0321 0.1041
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0198 0.0802
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0355 0.1032
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1569 0.4612
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0052 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Echinococcus granulosus importin subunit beta 1 0.0033 0.0117 0.0302
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0111 0.0578 0.3624
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0032 0.0032
Onchocerca volvulus 0.0022 0.0052 0.0207
Schistosoma mansoni ap endonuclease 0.0018 0.0033 0.0082
Brugia malayi hypothetical protein 0.0025 0.0072 0.023
Echinococcus granulosus Chromobox protein 3 0.0013 0.0001 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0001 0.00000000014349
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0184 0.0597
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0083
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0052 0.0165
Echinococcus granulosus chromobox protein 2 0.0013 0.0001 0.0003
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0464 0.1357
Onchocerca volvulus 0.0035 0.0128 0.0519
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0081 0.0398 0.1293
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0229 0.0628
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0048 0.0123
Echinococcus multilocularis chromobox protein 1 0.0079 0.0387 0.0387
Brugia malayi jmjC domain containing protein 0.0015 0.0015 0.0045
Onchocerca volvulus 0.0073 0.0355 0.1445
Brugia malayi jmjC domain containing protein 0.0061 0.0281 0.0913
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0033 0.063
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0021 0.0021
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0065 0.0104
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0108 0.035
Schistosoma mansoni hypothetical protein 0.0031 0.0108 0.0278
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0052 0.006
Schistosoma mansoni hypothetical protein 0.0013 0.0001 0.00000000011403
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0135 0.0437
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0052 0.1005
Schistosoma mansoni mannose-6-phosphate isomerase 0.0095 0.048 0.1241
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0001 0.00000000014349
Entamoeba histolytica hypothetical protein 0.0041 0.0164 0.1023
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0056 0.0253 0.0822
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0066 0.0212
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0089 0.0253
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0043 0.0179 0.1121
Loa Loa (eye worm) hypothetical protein 0.0055 0.0247 0.08
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0059 0.0084
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0072 0.14
Echinococcus granulosus mannose 6 phosphate isomerase 0.0095 0.048 0.1243
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0059 0.0084
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0052 0.0165
Echinococcus multilocularis chromobox protein 2 0.0013 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0464 0.151
Schistosoma mansoni ran 0.0024 0.0066 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0464 0.12
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0052 0.006
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0059 0.1148
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0281 0.0726
Trichomonas vaginalis importin beta-1, putative 0.0026 0.008 0.0259
Loa Loa (eye worm) hypothetical protein 0.0432 0.2452 0.7989
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.0414 0.1209
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0033 0.0033
Loa Loa (eye worm) calcium channel 0.0094 0.0474 0.154
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0032 0.0102
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0015 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0072 0.02
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0033 0.0103
Loa Loa (eye worm) hypothetical protein 0.0055 0.0247 0.08
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0048 0.0152
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0272 0.0701
Plasmodium vivax JmjC domain containing protein 0.0015 0.0015 0.0276
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0066 0.0184
Leishmania major DNA polymerase eta, putative 0.0078 0.0382 0.1115
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0117 0.0333
Schistosoma mansoni DNA polymerase IV / kappa 0.0028 0.0089 0.0229
Entamoeba histolytica Ran family GTPase 0.0024 0.0066 0.0409
Brugia malayi jmjC domain containing protein 0.0057 0.0261 0.0847
Trichomonas vaginalis helicase, putative 0.0014 0.0006 0.0015
Schistosoma mansoni apoptosis regulator bax 0.0081 0.0398 0.1028
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0355 0.1036
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0247 0.0684
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0065 0.0182
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0065 0.0182
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0198 0.0509
Brugia malayi CXXC zinc finger family protein 0.0061 0.028 0.0908
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0059 0.0084
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0064 0.0177
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0235 0.0763
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0117 0.19
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0108 0.035
Toxoplasma gondii transporter, cation channel family protein 0.002 0.004 0.0645
Plasmodium vivax importin-beta 2, putative 0.0033 0.0117 0.2293
Entamoeba histolytica hypothetical protein 0.0041 0.0164 0.1023
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0108 0.0108
Trypanosoma brucei unspecified product 0.0062 0.0289 0.0842
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0135 0.0437
Loa Loa (eye worm) hypothetical protein 0.0055 0.0247 0.08
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0015 0.0036
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0052 0.0833
Loa Loa (eye worm) hypothetical protein 0.0035 0.0128 0.0415
Mycobacterium ulcerans hypothetical protein 0.0024 0.0065 0.0104
Loa Loa (eye worm) hypothetical protein 0.0053 0.0235 0.0763
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.049 0.1592
Schistosoma mansoni hypothetical protein 0.0102 0.0525 0.1358
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0052 0.006
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0272 0.0765
Mycobacterium ulcerans DNA polymerase IV 0.0116 0.0607 0.1839
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0355 0.1036
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0281 0.1569 0.4612
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0109 0.0351
Trypanosoma brucei chrX additional, unordered contigs 0.0028 0.0089 0.0253
Schistosoma mansoni hypothetical protein 0.0031 0.0108 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0094 0.0474 0.154
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0112 0.1817
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0066 0.1292
Toxoplasma gondii hypothetical protein 0.0017 0.0026 0.0417
Schistosoma mansoni ran 0.0024 0.0066 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0243 0.0707
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0015 0.0036
Trypanosoma cruzi phosphomannose isomerase, putative 0.0095 0.048 0.1404
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0112 0.0318
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0032 0.0513
Loa Loa (eye worm) hypothetical protein 0.0022 0.0052 0.0165
Brugia malayi Niemann-Pick C1 protein precursor 0.0111 0.0578 0.188
Schistosoma mansoni hypothetical protein 0.0067 0.0321 0.0827
Brugia malayi Pre-SET motif family protein 0.0031 0.011 0.0354
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0135 0.0437
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0052 0.006
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.009 0.0453 0.1171
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0464 0.151
Leishmania major DNA polymerase kappa, putative 0.0097 0.0492 0.1437
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0355 0.1154
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0052 0.006
Leishmania major importin beta-1 subunit, putative 0.0026 0.008 0.0226
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0001 0.00000000027661
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0135 0.0842
Loa Loa (eye worm) runx1 0.0054 0.0242 0.0787
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0052 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Trypanosoma cruzi DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Echinococcus multilocularis tumor protein p63 0.0383 0.2165 0.2165
Mycobacterium tuberculosis Conserved protein 0.0024 0.0065 0.0104
Echinococcus granulosus cpg binding protein 0.0064 0.03 0.0776
Trypanosoma cruzi DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Brugia malayi mbt repeat family protein 0.0046 0.0198 0.0641
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0001 0.00000000014349
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0052 0.0833
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0003 0.0008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0135 0.0842
Echinococcus granulosus microtubule associated protein 2 0.0673 0.3862 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0021 0.0055
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0164 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0001 0.00000000027661
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.049 0.1267
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.008 0.0259
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.011 0.0282
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0128
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0033 0.0103
Trichomonas vaginalis rotamase, putative 0.0032 0.0112 0.036
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0578 0.1496
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0355 0.1032
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0387 0.1258
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0065 0.0104
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0247 0.0684
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.04 0.1299
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0116 0.0375
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0015 0.0015
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0015 0.0045
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.1593 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0089 0.0253
Loa Loa (eye worm) hypothetical protein 0.0073 0.0355 0.1154
Trypanosoma brucei phosphomannose isomerase 0.0095 0.048 0.1404
Loa Loa (eye worm) hypothetical protein 0.0432 0.2452 0.7989
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.0262
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0355 0.1154
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0034 0.0126 0.0126
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0094 0.0474 0.154
Schistosoma mansoni chromobox protein 0.0079 0.0387 0.1
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0015 0.0039
Trypanosoma brucei DNA polymerase IV, putative 0.0116 0.0607 0.1779
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0355 0.1032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0229 0.0628
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.003 0.0102 0.0289
Echinococcus granulosus amyloid beta A4 protein 0.0067 0.0317 0.0822
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0135 0.0437
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0091 0.0457 0.1359
Loa Loa (eye worm) hypothetical protein 0.0081 0.0398 0.1293
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0113 0.0588 0.152
Brugia malayi CHE-14 protein 0.0048 0.0205 0.0666
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0094 0.0474 0.0474
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0198 0.0198
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0033 0.0085
Schistosoma mansoni hypothetical protein 0.0081 0.0398 0.1028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0102
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1291 0.4203
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0135 0.0387
Echinococcus multilocularis protein patched 0.0048 0.0205 0.0205
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0033 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.011 0.0282
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0229 0.0628
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0387 0.1258
Loa Loa (eye worm) apoptosis regulator protein 0.0081 0.0398 0.1293
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.087 0.087
Echinococcus multilocularis Chromobox protein 3 0.0013 0.0001 0.0001
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0052 0.0131
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0059 0.1148
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0593 0.3399 1
Echinococcus multilocularis Protein lozenge 0.0054 0.0242 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0328 0.0955
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0272 0.0704
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0052 0.006
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0052 0.006
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0198 0.0512
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.074 0.2263
Echinococcus multilocularis snurportin 1 0.0348 0.1965 0.1965
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0052 0.1005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.049 0.1265
Loa Loa (eye worm) RecQ helicase 0.0044 0.0184 0.0597
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0072 0.02
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0015 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Trypanosoma brucei glucosidase, putative 0.0036 0.0135 0.0387
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0272 0.0701
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0065 0.0104
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0099 0.0505 0.1642
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0003 0.0008
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0414 0.1209
Leishmania major mitochondrial DNA polymerase beta 0.0593 0.3399 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0052 0.0052
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0057 0.0259 0.0752
Loa Loa (eye worm) X11 protein 0.0067 0.0317 0.1031
Echinococcus granulosus expressed conserved protein 0.0105 0.0538 0.1394
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0204 0.0661
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.087 0.2831
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0097 0.0492 0.1468
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0052 0.006
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.0001 0.00000000072426
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0052 0.006
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0247 0.4875
Loa Loa (eye worm) hypothetical protein 0.0081 0.04 0.1299
Brugia malayi ImpB/MucB/SamB family protein 0.009 0.0453 0.1474
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0033 0.0103
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0094 0.0474 0.0474
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0272 0.0765
Onchocerca volvulus 0.0093 0.0472 0.192
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0095 0.048 0.1562
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0064 0.0204
Brugia malayi CHD4 protein 0.0016 0.0021 0.0066
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0052 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.0262
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0184 0.0748
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0015 0.0039
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0552 0.3158 1
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0095 0.048 0.1562
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0059 0.0951
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0272 0.0765
Schistosoma mansoni cpg binding protein 0.0064 0.03 0.0774
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Leishmania major phosphomannose isomerase 0.0095 0.048 0.1404
Schistosoma mansoni terminal deoxycytidyl transferase 0.009 0.0453 0.1171
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0052 0.0318
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.009 0.0453 0.1174
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0066 0.0217
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0355 0.1154
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0355 0.0977
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0033 0.0199
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0229 0.0628
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0091 0.0457 0.1337
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0184 0.0184
Loa Loa (eye worm) oxidoreductase 0.0022 0.0052 0.0165
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0101 0.0518 0.8507
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0503 0.1637
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0032 0.0513
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0286 0.1601 0.4145
Loa Loa (eye worm) glutaminase 0.0537 0.307 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0108 0.028
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0135 0.0437
Trichomonas vaginalis DNA polymerase eta, putative 0.0116 0.0607 0.1976
Entamoeba histolytica hypothetical protein 0.0023 0.0059 0.0363
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0116 0.0375
Mycobacterium ulcerans hypothetical protein 0.0101 0.0518 0.1553
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0198 0.0509
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0001 0.00000000027661
Echinococcus multilocularis Chromo domain 0.0013 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0024 0.0065 0.0104
Schistosoma mansoni lozenge 0.0054 0.0242 0.0625
Loa Loa (eye worm) hypothetical protein 0.0073 0.0355 0.1154
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.008 0.0259
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0091 0.0457 0.2722
Brugia malayi jmjC domain containing protein 0.0015 0.0015 0.0045
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0072 0.14
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0355 0.0977
Echinococcus multilocularis protein dispatched 1 0.0055 0.0245 0.0245
Echinococcus multilocularis GPCR, family 2 0.0031 0.0108 0.0108
Echinococcus multilocularis Niemann Pick C1 protein 0.0159 0.0858 0.0858
Schistosoma mansoni amyloid beta A4 protein related 0.0067 0.0317 0.0819
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0078 0.0382 0.6271
Brugia malayi RNA, U transporter 1 0.0093 0.0469 0.1525
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0001 0.00000000014349
Schistosoma mansoni DNA helicase recq5 0.0018 0.0032 0.0081
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.087 0.2252
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0026 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Leishmania major DNA polymerase eta, putative 0.014 0.0746 0.2187
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Loa Loa (eye worm) voltage-dependent calcium channel 0.002 0.004 0.0128
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0052 0.006
Giardia lamblia DINP protein human, muc B family 0.0097 0.0492 0.2943
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0064 0.0177
Onchocerca volvulus 0.0432 0.2452 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0044 0.014
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0052 0.0142
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0059 0.0084
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0033 0.0086
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0052 0.006
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0108 0.028
Mycobacterium tuberculosis Conserved hypothetical protein 0.0101 0.0518 0.1553
Schistosoma mansoni hypothetical protein 0.0348 0.1965 0.5088
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0032 0.011 0.0247
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0253 0.0653
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.00000000014349
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.009 0.0453 0.1474
Entamoeba histolytica deoxycytidyl transferase, putative 0.009 0.0453 0.2841
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0059 0.0167
Schistosoma mansoni microtubule-associated protein tau 0.0673 0.3862 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.011 0.0354
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0065 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0328 0.0955
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0261 0.0673
Echinococcus multilocularis microtubule associated protein 2 0.0673 0.3862 0.3862
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0072 0.02
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0081 0.0398 0.103
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0052 0.0142
Entamoeba histolytica hypothetical protein 0.0041 0.0164 0.1023
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0052 0.0165
Echinococcus multilocularis voltage dependent calcium channel 0.0094 0.0474 0.0474
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0035 0.0035
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0052 0.0833
Schistosoma mansoni hypothetical protein 0.0046 0.0195 0.0503
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0112 0.0318
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.04 0.1033
Toxoplasma gondii hypothetical protein 0.0096 0.0486 0.7972
Onchocerca volvulus 0.0056 0.0253 0.1029
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0083
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0099 0.0505 1
Loa Loa (eye worm) heterochromatin protein 1 0.0079 0.0387 0.1258
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0235 0.0235
Schistosoma mansoni cpg binding protein 0.0064 0.03 0.0774
Brugia malayi mbt repeat family protein 0.0046 0.0198 0.0641
Schistosoma mansoni hypothetical protein 0.0046 0.0195 0.0503
Schistosoma mansoni chromobox protein 0.0079 0.0387 0.1
Brugia malayi polk-prov protein 0.0054 0.0243 0.079
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.049 0.1267
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0048 0.0048
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0135 0.2204
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0051 0.0226 0.0562
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0192 0.0623
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0033 0.0086
Echinococcus granulosus tumor protein p63 0.0383 0.2165 0.5605
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0066 0.0184
Trypanosoma brucei hypothetical protein, conserved 0.0207 0.1139 0.3344
Loa Loa (eye worm) hypothetical protein 0.0134 0.0712 0.2317
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.023
Schistosoma mansoni SET domain protein 0.0016 0.002 0.005
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0464 0.0464
Onchocerca volvulus 0.0044 0.0185 0.0752
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0052 0.0165
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0032 0.0083
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0205 0.0532
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0064 0.0177
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.049 0.049
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0015 0.0229
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0052 0.0142
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0094 0.0474 0.1226
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0112 0.0318
Mycobacterium ulcerans hypothetical protein 0.0073 0.0355 0.1032
Brugia malayi jmjC domain containing protein 0.0015 0.0015 0.0045
Echinococcus multilocularis expressed conserved protein 0.0105 0.0538 0.0538
Onchocerca volvulus 0.0013 0.0001 0.0000000291
Schistosoma mansoni glutaminase 0.0537 0.307 0.7947
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0247 0.4875
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0015 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.011 0.0569 0.1666
Schistosoma mansoni alpha-glucosidase 0.0139 0.0738 0.191
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0015 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0003 0.0008
Schistosoma mansoni hypothetical protein 0.0031 0.0108 0.0278
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.004 0.0158 0.0409
Entamoeba histolytica hypothetical protein 0.0041 0.0164 0.1023
Onchocerca volvulus 0.0025 0.0074 0.0296
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0204 0.0828
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0094 0.0474 0.0474
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0015 0.0015
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.008 0.0226
Echinococcus multilocularis cpg binding protein 0.0064 0.03 0.03
Plasmodium falciparum importin beta, putative 0.0033 0.0117 0.2293
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0355 0.1032
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0464 0.1202
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0464 0.2911
Loa Loa (eye worm) hypothetical protein 0.0044 0.0184 0.0597
Brugia malayi ImpB/MucB/SamB family protein 0.014 0.0746 0.2429
Brugia malayi chromobox protein homolog 3 0.0044 0.0184 0.0597
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0052 0.0134
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0116 0.0607 0.1779
Loa Loa (eye worm) hypothetical protein 0.0048 0.0205 0.0666
Brugia malayi hypothetical protein 0.0064 0.0302 0.0981
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0272 0.0272
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0503 0.1637
Schistosoma mansoni hypothetical protein 0.0031 0.0108 0.0278
Plasmodium falciparum DNA repair protein REV1, putative 0.0028 0.0089 0.1752
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0464 0.151
Onchocerca volvulus 0.0022 0.0052 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0205 0.0666
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0059 0.0273 0.0768
Mycobacterium ulcerans hypothetical protein 0.0028 0.0089 0.0181
Brugia malayi Heterochromatin protein 1 0.0079 0.0387 0.1258
Leishmania major hypothetical protein, conserved 0.0015 0.0015 0.0034
Leishmania major DNA polymerase kappa, putative 0.0028 0.0089 0.0253
Schistosoma mansoni hypothetical protein 0.0046 0.0195 0.0503
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0593 0.3399 1
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0052 0.0142
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0235 0.0609
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0015 0.0039
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0028 0.0089 0.1452
Echinococcus granulosus phd:f box containing protein 0.0015 0.0015 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0057 0.0259 0.0752
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0205 0.0666
Loa Loa (eye worm) hypothetical protein 0.0055 0.0247 0.08
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.04 0.04
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.011 0.0282
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0235 0.0607
Echinococcus multilocularis expressed protein 0.0033 0.0116 0.0116
Onchocerca volvulus 0.0022 0.0052 0.0207
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0112 0.0694
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0021 0.0052
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0032 0.0032
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0052 0.006
Brugia malayi glucose-6-phosphate dehydrogenase 0.0091 0.0457 0.1487
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Trypanosoma brucei RNA helicase, putative 0.0102 0.0525 0.1537
Trypanosoma cruzi hypothetical protein, conserved 0.0207 0.1139 0.3344
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0464 0.151
Echinococcus multilocularis amyloid beta A4 protein 0.0067 0.0317 0.0317
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0187 0.1019 0.2639
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0003 0.0008
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0052 0.006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0198 0.0641
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0135 0.035
Echinococcus multilocularis sodium channel protein 0.004 0.0158 0.0158
Echinococcus multilocularis dna polymerase kappa 0.0116 0.0607 0.0607
Mycobacterium ulcerans hypothetical protein 0.0313 0.1755 0.5511
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0003 0.0008
Toxoplasma gondii exonuclease III APE 0.0018 0.0033 0.0522
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0026 0.0067
Echinococcus granulosus dna polymerase eta 0.014 0.0746 0.1932
Mycobacterium tuberculosis Conserved hypothetical protein 0.0313 0.1755 0.5511
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0198 0.0509
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0198 0.0198
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0052 0.006
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0081 0.0398 0.0398
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0464 0.1357
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0117 0.0333
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0033 0.0086
Mycobacterium ulcerans hypothetical protein 0.0101 0.0518 0.1553
Echinococcus granulosus snurportin 1 0.0348 0.1965 0.5089
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0198 0.0512
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0033 0.0003
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0464 0.151
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0003 0.001
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0099 0.0505 0.8286
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0095 0.048 0.9511
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0609 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0052 0.0165
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0272 0.0765
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0052 0.0142
Plasmodium vivax SET domain protein, putative 0.0031 0.011 0.2158
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0281 0.0913
Onchocerca volvulus 0.0171 0.0927 0.3777
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.013 0.0333
Schistosoma mansoni voltage-gated cation channel 0.0094 0.0474 0.1224
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0003 0.0008
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0153 0.3011
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0095 0.048 0.1562
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0095 0.048 0.048
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0089 0.0253
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1593 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0072 0.116
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0355 0.2225
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0116 0.0375
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0281 0.0728
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0052 0.006
Echinococcus granulosus Chromo domain 0.0013 0.0001 0.0003
Schistosoma mansoni alpha glucosidase 0.0036 0.0135 0.0347
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0001 0.00000000011403
Echinococcus multilocularis chromobox protein 1 0.0079 0.0387 0.0387
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0689 0.1782
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.2259 0.2259
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0046 0.0147
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0135 0.0437
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0464 0.151
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Trichomonas vaginalis glutaminase, putative 0.0537 0.307 1
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0091 0.0457 0.1337
Treponema pallidum licC protein (licC) 0.0101 0.0518 0.3112
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0355 0.2225
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0052 0.0165
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.1593 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0094 0.0474 0.0474
Trypanosoma brucei unspecified product 0.011 0.0569 0.1666
Brugia malayi hypothetical protein 0.0432 0.2452 0.7989
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.006 0.0276 0.0896
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0135 0.0437
Echinococcus granulosus chromobox protein 1 0.0079 0.0387 0.1002
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0099 0.0505 0.1642
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0185 0.0477
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.028 0.0908
Schistosoma mansoni ap endonuclease 0.0018 0.0033 0.0082
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0121
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0065 0.0104
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0593 0.3399 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.0262
Brugia malayi glutaminase DH11.1 0.0537 0.307 1
Echinococcus granulosus GPCR family 2 0.0031 0.0108 0.028
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0015 0.0036
Mycobacterium tuberculosis Conserved hypothetical protein 0.0101 0.0518 0.1553
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.087 0.087
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0205 0.0532
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0091 0.0457 0.0457
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.01 0.1972
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.0001 0.0003
Toxoplasma gondii phosphomannose isomerase type I protein 0.0095 0.048 0.7882
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.0717 0.2332
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0135 0.0437
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0281 0.1569 0.4612
Mycobacterium ulcerans DNA polymerase IV 0.0116 0.0607 0.1839
Trypanosoma cruzi DNA polymerase eta, putative 0.0078 0.0382 0.1115
Brugia malayi hypothetical protein 0.0171 0.0927 0.3017
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0095 0.048 0.1562
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0464 0.1357
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0108 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0355 0.1032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0098 0.16
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0135 0.0437
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0552 0.3158 1
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0184 0.0597
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0052 0.0142
Loa Loa (eye worm) glutaminase 2 0.0537 0.307 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0091 0.0457 0.1337
Brugia malayi MH2 domain containing protein 0.0135 0.0717 0.2332
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0089 0.0253
Onchocerca volvulus 0.0233 0.1291 0.5262
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0015 0.0229
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0003 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0192 0.0623
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0044 0.014
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0135 0.0437
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0032 0.0102
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0032 0.0083
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.011 0.011
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0099 0.0505 0.3028
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0015 0.0276
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0052 0.0165
Trypanosoma cruzi DNA polymerase eta, putative 0.014 0.0746 0.2187
Mycobacterium tuberculosis Conserved hypothetical protein 0.009 0.0453 0.1346
Loa Loa (eye worm) hypothetical protein 0.014 0.0746 0.2429
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0052 0.006
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0059 0.0273 0.4472
Brugia malayi jmjC domain containing protein 0.0015 0.0015 0.0045
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0321 0.1041
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0081 0.0398 0.103
Schistosoma mansoni alpha-glucosidase 0.0139 0.0738 0.191
Echinococcus multilocularis dna polymerase eta 0.014 0.0746 0.0746
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.0001 0.00000000087403
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0026 0.0067
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0072 0.14
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0052 0.0142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.0262
Entamoeba histolytica phosphomannose isomerase, putative 0.0095 0.048 0.301
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0097 0.0492 0.1437
Brugia malayi hypothetical protein 0.0016 0.002 0.0061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0052 0.006
Loa Loa (eye worm) hypothetical protein 0.0064 0.0302 0.0981
Trypanosoma brucei polo-like protein kinase 0.0092 0.0464 0.1357
Mycobacterium ulcerans glutaminase 0.0537 0.307 0.9717
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0094 0.0474 0.1226
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Schistosoma mansoni hypothetical protein 0.0041 0.0164 0.0422
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.0414 0.1209
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.1127 0.3669
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0272 0.079
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0066 0.0212
Schistosoma mansoni rotamase 0.0033 0.0116 0.0298
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0135 0.0387
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0135 0.0387
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0052 0.0165
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0091 0.0457 1
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0065 0.0065
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0055 0.0247 0.08
Echinococcus granulosus dna polymerase kappa 0.0116 0.0607 0.1573
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0171 0.0927 0.3017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.049 0.1265
Echinococcus multilocularis voltage dependent calcium channel 0.0094 0.0474 0.0474
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0052 0.006
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0029 0.0097 0.0274
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0089 0.0253
Brugia malayi SET domain containing protein 0.0016 0.0021 0.0066
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0059 0.0023
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0083 0.0414 0.1209
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0045
Onchocerca volvulus 0.0081 0.04 0.1627
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0059 0.0163
Giardia lamblia DNA damage repair protein 0.0028 0.0089 0.0365
Echinococcus granulosus dnaJ subfamily B 0.0399 0.2259 0.5849
Leishmania major hypothetical protein, conserved 0.0025 0.0072 0.02
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0187 0.1019 0.1019
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0108 0.035
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0552 0.3158 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0081 0.0262
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0081 0.0398 0.1028
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0089 0.0253
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0051 0.0226 0.0619
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0281 0.0726
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Loa Loa (eye worm) hypothetical protein 0.0099 0.0503 0.1637
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0355 0.1032
Entamoeba histolytica hypothetical protein 0.0013 0.0001 0.00000000027661
Loa Loa (eye worm) hypothetical protein 0.0054 0.0243 0.079
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.011 0.011
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0261 0.0261
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0032 0.062
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0095 0.048 0.1562
Brugia malayi Importin beta-1 subunit 0.0033 0.0117 0.0376
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0066 0.1292
Schistosoma mansoni hypothetical protein 0.0046 0.0195 0.0503
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0464 0.151
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0111 0.0578 0.188
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.1593 0.5188
Echinococcus granulosus voltage dependent calcium channel 0.0094 0.0474 0.1226
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.011 0.0284
Loa Loa (eye worm) hypothetical protein 0.0073 0.0355 0.1154
Plasmodium vivax DNA repair protein REV1, putative 0.0028 0.0089 0.1752
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0035 0.0091
Leishmania major hypothetical protein, conserved 0.0207 0.1139 0.3344
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0065 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0109 0.0351
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0003 0.0008
Echinococcus granulosus expressed protein 0.0033 0.0116 0.03
Echinococcus granulosus Niemann Pick C1 protein 0.0159 0.0858 0.2221
Trypanosoma brucei DNA polymerase kappa, putative 0.0116 0.0607 0.1779
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0243 0.0707
Schistosoma mansoni hypothetical protein 0.0081 0.0398 0.1028
Schistosoma mansoni hypothetical protein 0.0081 0.0398 0.1028
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.074 0.2216
Leishmania major GTP-binding protein, putative 0.0024 0.0066 0.0184
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0521 0.1523
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0328 0.0955
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0164 0.0424
Loa Loa (eye worm) MBCTL1 0.0053 0.0235 0.0763
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0091 0.0457 0.1184
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0015 0.0045
Schistosoma mansoni SET domain protein 0.0034 0.0126 0.0325
Trypanosoma brucei unspecified product 0.0062 0.0289 0.0842
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0094 0.0474 0.1224
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0348 0.1965 0.6402
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0052 0.0165
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0089 0.0253
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0081 0.0398 0.0398
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.1593 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0081 0.0262
Trypanosoma cruzi hypothetical protein, conserved 0.0207 0.1139 0.3344
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0059 0.0951
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0015 0.0015
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0116 0.0607 0.1976
Giardia lamblia Kinase, PLK 0.0092 0.0464 0.2769
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0355 0.1036
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0091 0.0457 0.1487
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0034 0.0004
Trypanosoma brucei DNA polymerase eta, putative 0.014 0.0746 0.2187
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0032 0.0102
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0026 0.0065
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.049 0.1592
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0464 0.151
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0059 0.0163
Loa Loa (eye worm) hypothetical protein 0.0033 0.0117 0.0376
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0184 0.0597
Schistosoma mansoni cpg binding protein 0.0061 0.028 0.0722
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0464 0.189
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.074 0.2263
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.0262
Leishmania major DNA damage repair protein, putative 0.0028 0.0089 0.0253
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0164 0.0422
Brugia malayi Pre-SET motif family protein 0.0205 0.1127 0.3669
Onchocerca volvulus 0.0046 0.0198 0.0802
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0001 0.00000000087403
Schistosoma mansoni DNA polymerase eta 0.014 0.0746 0.193
Trichomonas vaginalis ran, putative 0.0024 0.0066 0.0212
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0066 0.0171
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.0717 0.2332
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0052 0.006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0052 0.006
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0198 0.0641
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0003 0.0016
Trichomonas vaginalis rotamase, putative 0.0033 0.0116 0.0375
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0094 0.0474 0.1226
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0052 0.0165
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.049 0.1265
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0015 0.0045
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0099 0.0505 1
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0064 0.0393
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0184 0.0597
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0355 0.1032
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0355 0.1032
Trypanosoma cruzi phosphomannose isomerase, putative 0.0095 0.048 0.1404
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0112 0.0318
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0205 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0015
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.0001 0.00000000014349
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0031 0.0108 0.035

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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