Detailed information for compound 989630

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 801.017 | Formula: C51H60O8
  • H donors: 0 H acceptors: 4 LogP: 11.54 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=C)[C@@H]([C@H](C[C@H]([C@@]12CC[C@]3([C@]2(O1)C[C@H](OC(=O)c1ccccc1)[C@@H]1[C@]3(C)CC[C@@H]2[C@]1(C)CCC(=O)C2(C)C)C)C)OC(=O)c1ccccc1)OC(=O)c1ccccc1
  • InChi: 1S/C51H60O8/c1-32(2)41(58-45(55)36-22-16-11-17-23-36)37(56-43(53)34-18-12-9-13-19-34)30-33(3)50-29-28-49(8)48(7)27-24-39-46(4,5)40(52)25-26-47(39,6)42(48)38(31-51(49,50)59-50)57-44(54)35-20-14-10-15-21-35/h9-23,33,37-39,41-42H,1,24-31H2,2-8H3/t33-,37+,38+,39+,41+,42+,47+,48+,49-,50-,51-/m1/s1
  • InChiKey: UCACVVOLXNQHFU-PRAJVVKWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus lamin 0.0054 0.0249 0.0248
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0189 0.1092 1
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0048 0.0429
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0125 0.0694 0.0694
Toxoplasma gondii hypothetical protein 0.0118 0.0649 0.1244
Trypanosoma cruzi lanosterol synthase, putative 0.0032 0.0109 0.0988
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0125 0.0694 0.0694
Leishmania major hypothetical protein, conserved 0.0031 0.0104 0.0942
Echinococcus multilocularis fibrillin 1 0.0077 0.0393 0.0392
Echinococcus multilocularis microtubule associated protein 2 0.1382 0.8572 0.8572
Entamoeba histolytica hypothetical protein 0.007 0.035 0.5996
Brugia malayi Cadherin domain containing protein 0.0065 0.0314 0.0677
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0039 0.0153 0.0178
Plasmodium falciparum ataxin-2 like protein, putative 0.0085 0.0441 0.757
Echinococcus granulosus delta-like protein 1 0.0065 0.0314 0.0313
Brugia malayi hypothetical protein 0.006 0.0285 0.0613
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0074 0.0085
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0119 0.0654 0.0762
Echinococcus granulosus neural cadherin 0.0065 0.0314 0.0313
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.006 0.0285 0.2952
Loa Loa (eye worm) hypothetical protein 0.0093 0.049 0.1056
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Brugia malayi EGF-like domain containing protein 0.0065 0.0314 0.0677
Onchocerca volvulus Cathepsin F homolog 0.0022 0.0048 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0168 0.0964 0.2081
Schistosoma mansoni hypothetical protein 0.011 0.0597 0.0695
Loa Loa (eye worm) PAN domain-containing protein 0.0054 0.025 0.0537
Echinococcus granulosus cyclin dependent kinase 5 0.0026 0.0074 0.0073
Mycobacterium ulcerans monoamine oxidase 0.006 0.0285 0.0451
Onchocerca volvulus 0.0022 0.0048 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0055 0.0111
Brugia malayi notch-like transmembrane receptor 0.0065 0.0314 0.0677
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0137 0.1418
Echinococcus multilocularis expressed conserved protein 0.0048 0.0209 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Schistosoma mansoni hypothetical protein 0.0065 0.0314 0.0366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0046 0.0092
Echinococcus multilocularis lamin 0.0054 0.0249 0.0248
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0125 0.0694 0.0809
Brugia malayi hypothetical protein 0.007 0.035 0.0753
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0029 0.0091 0.0185
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0012 0.0011
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0038 0.0148 0.0147
Brugia malayi beta-lactamase family protein 0.0168 0.0964 0.2081
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Schistosoma mansoni hypothetical protein 0.011 0.0597 0.0695
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.011 0.0597 0.0695
Brugia malayi hypothetical protein 0.0055 0.0253 0.0543
Loa Loa (eye worm) hypothetical protein 0.011 0.0597 0.1287
Echinococcus multilocularis thyroid hormone receptor alpha 0.0175 0.1006 0.1005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0023 0.005 0.0049
Echinococcus multilocularis transcription factor btf3 0.0022 0.0049 0.0048
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0168 0.0964 0.1385
Schistosoma mansoni transcription factor LCR-F1 0.007 0.035 0.0407
Loa Loa (eye worm) hypothetical protein 0.0039 0.0153 0.0329
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0073 0.0072
Echinococcus multilocularis peregrin 0.0054 0.0245 0.0244
Onchocerca volvulus 0.0022 0.0048 0.008
Echinococcus granulosus thioredoxin glutathione reductase 0.0065 0.0317 0.0316
Giardia lamblia Cathepsin B precursor 0.0042 0.0169 0.2886
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0032 0.0111 0.1011
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Toxoplasma gondii PAN domain-containing protein 0.0846 0.5212 1
Echinococcus granulosus protein jagged 2 0.0065 0.0314 0.0313
Onchocerca volvulus 0.0021 0.0039 0.0062
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0149 0.084 0.1196
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0122 0.0675 0.1295
Trypanosoma brucei cdc2-related kinase 3 0.0026 0.0074 0.0669
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0162 0.0924 0.0923
Onchocerca volvulus 0.0065 0.0314 0.0627
Loa Loa (eye worm) hypothetical protein 0.0118 0.0649 0.1399
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.002 0.0034 0.0072
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0023 0.005 0.0049
Brugia malayi Trypsin family protein 0.011 0.0597 0.1287
Brugia malayi EGF-like domain containing protein 0.0065 0.0314 0.0677
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0034 0.0304
Brugia malayi PHD-finger family protein 0.0061 0.0288 0.0619
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.006 0.0285 0.0613
Giardia lamblia Cathepsin B precursor 0.0042 0.0169 0.2886
Echinococcus granulosus neurogenic locus notch protein 0.0065 0.0314 0.0313
Loa Loa (eye worm) hypothetical protein 0.006 0.0285 0.0613
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0168 0.0964 0.1758
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0029 0.0091 0.0175
Plasmodium vivax SET domain protein, putative 0.01 0.0535 0.5551
Loa Loa (eye worm) hypothetical protein 0.0753 0.4631 1
Echinococcus multilocularis neurogenic locus notch protein 4 0.0065 0.0314 0.0313
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0023 0.005 0.0057
Echinococcus multilocularis cathepsin b 0.0119 0.0654 0.0653
Toxoplasma gondii PAN/Apple domain-containing protein 0.0054 0.025 0.0479
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0015 0.0001 0.0017
Toxoplasma gondii ABC1 family protein 0.0168 0.0964 0.185
Toxoplasma gondii cathepsin B 0.0042 0.0169 0.0324
Brugia malayi Trypsin family protein 0.0753 0.4631 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0119 0.0654 0.0762
Loa Loa (eye worm) hypothetical protein 0.0053 0.0243 0.0522
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0135 0.0753 0.0752
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Echinococcus multilocularis protein jagged 1 0.0065 0.0314 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0066 0.0134
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0027 0.0075 0.0677
Onchocerca volvulus 0.006 0.0285 0.0566
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0012 0.0011
Brugia malayi EGF-like domain containing protein 0.0065 0.0314 0.0677
Brugia malayi PHD-finger family protein 0.0017 0.0013 0.0026
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Onchocerca volvulus 0.0054 0.025 0.0494
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0697 0.4279 0.924
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Schistosoma mansoni jumonji domain containing protein 0.0102 0.0546 0.0636
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0172 0.0369
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0036 0.0137 0.1244
Toxoplasma gondii cathepsin CPL 0.0022 0.0048 0.0092
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0022 0.0048 0.082
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0077 0.0393 0.0846
Echinococcus multilocularis fat cadherin tumor suppressor 0.0065 0.0314 0.0313
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0126 0.0146
Plasmodium vivax SET domain containing protein 0.0018 0.0023 0.0239
Echinococcus multilocularis PHD finger protein rhinoceros 0.0039 0.0153 0.0153
Echinococcus multilocularis cathepsin L cysteine protease 0.0022 0.0048 0.0047
Echinococcus multilocularis laminin 0.0077 0.0393 0.0392
Mycobacterium ulcerans hypothetical protein 0.0168 0.0964 0.1758
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0042 0.0169 0.0344
Toxoplasma gondii NADPH-glutathione reductase 0.0023 0.005 0.0096
Plasmodium vivax protein kinase Crk2 0.0026 0.0074 0.0767
Echinococcus granulosus glycoprotein Antigen 5 0.0202 0.1177 0.1176
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.0074 0.0149
Toxoplasma gondii PHD-finger domain-containing protein 0.0039 0.0153 0.0294
Toxoplasma gondii microneme protein, putative 0.0054 0.025 0.0479
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Trypanosoma cruzi protein farnesyltransferase, putative 0.0029 0.0091 0.0826
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0089 0.0469 0.4286
Onchocerca volvulus Cathepsin L homolog 0.0022 0.0048 0.008
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0029 0.0091 0.0185
Onchocerca volvulus 0.0054 0.0249 0.0493
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.001 0.0019
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0091 0.0194
Brugia malayi GCC2 and GCC3 family protein 0.0065 0.0314 0.0677
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0029 0.0093 0.1598
Onchocerca volvulus 0.0168 0.0964 0.196
Leishmania major basic transcription factor 3a, putative 0.0022 0.0049 0.0443
Brugia malayi jmjC domain containing protein 0.0051 0.0229 0.0493
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0075 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Toxoplasma gondii calcium binding egf domain-containing protein 0.0077 0.0393 0.0753
Trypanosoma cruzi UDP-galactopyranose mutase 0.006 0.0285 0.2599
Onchocerca volvulus 0.011 0.0597 0.1207
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0089 0.0469 0.4286
Mycobacterium tuberculosis Probable dehydrogenase 0.0149 0.084 0.1196
Loa Loa (eye worm) hypothetical protein 0.0168 0.0964 0.2081
Echinococcus granulosus intermediate filament protein 0.0054 0.0249 0.0248
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0091 0.0185
Echinococcus granulosus sodium bile acid cotransporter 0.0247 0.1454 0.1453
Echinococcus multilocularis geminin 0.0216 0.126 0.126
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0026 0.0074 0.0669
Entamoeba histolytica Ran family GTPase 0.0015 0.0001 0.0017
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0022 0.0048 0.082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0168 0.0964 0.2081
Schistosoma mansoni hypothetical protein 0.0216 0.126 0.1469
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.011 0.0597 0.0695
Toxoplasma gondii kringle domain-containing protein 0.0051 0.0225 0.0432
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0029 0.0091 0.009
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0023 0.005 0.0449
Mycobacterium tuberculosis Conserved protein 0.0168 0.0964 0.1385
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0122 0.0675 0.138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0046 0.0092
Onchocerca volvulus 0.0065 0.0314 0.0627
Plasmodium falciparum glutathione reductase 0.0023 0.005 0.0856
Trichomonas vaginalis D-aminoacylase, putative 0.0168 0.0964 0.1973
Brugia malayi hypothetical protein 0.011 0.0597 0.1287
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Echinococcus granulosus histone acetyltransferase KAT2B 0.0122 0.0675 0.0674
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0029 0.0091 0.1562
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0029 0.0093 0.0092
Echinococcus multilocularis protoporphyrinogen oxidase 0.006 0.0285 0.0284
Loa Loa (eye worm) hypothetical protein 0.02 0.1162 0.2508
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0131 0.0732 0.0731
Leishmania major farnesyltransferase beta subunit 0.0029 0.0091 0.0826
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0852 0.5251 1
Schistosoma mansoni chromobox protein 0.0048 0.0206 0.0239
Schistosoma mansoni amine oxidase 0.006 0.0285 0.0331
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.005 0.0449
Echinococcus granulosus cyclin dependent kinase 1 0.0026 0.0074 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0049 0.0099
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0036 0.0137 0.2345
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0285 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0093 0.0189
Schistosoma mansoni transcription factor btf3 0.0022 0.0049 0.0056
Echinococcus granulosus neurogenic locus protein delta 0.0065 0.0314 0.0313
Leishmania major cysteine peptidase A (CPA) 0.0022 0.0048 0.0429
Trypanosoma brucei lanosterol synthase 0.0032 0.0109 0.0988
Trypanosoma cruzi target of rapamycin kinase 3 0.0023 0.0056 0.05
Mycobacterium tuberculosis Possible oxidoreductase 0.006 0.0285 0.0355
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0168 0.0964 0.1124
Echinococcus multilocularis protein jagged 1 0.0065 0.0314 0.0313
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0016 0.0009 0.0016
Echinococcus granulosus tissue type plasminogen activator 0.0051 0.0225 0.0224
Schistosoma mansoni hypothetical protein 0.0065 0.0314 0.0366
Entamoeba histolytica cell division protein kinase 2, putative 0.0026 0.0074 0.1268
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0029 0.0093 0.0845
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0015
Schistosoma mansoni cell polarity protein 0.0065 0.0314 0.0366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Schistosoma mansoni cellular tumor antigen P53 0.0236 0.1386 0.1615
Onchocerca volvulus Alhambra homolog 0.0039 0.0153 0.0297
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0027 0.0075 0.0136
Echinococcus multilocularis 0.006 0.0285 0.0284
Schistosoma mansoni notch 0.0065 0.0314 0.0366
Brugia malayi Thioredoxin reductase 0.0065 0.0317 0.0682
Trichomonas vaginalis D-aminoacylase, putative 0.0168 0.0964 0.1973
Echinococcus granulosus lysine specific demethylase 5A 0.0051 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.011 0.0597 0.1287
Echinococcus granulosus notch 0.0065 0.0314 0.0313
Onchocerca volvulus 0.0168 0.0964 0.196
Trypanosoma cruzi ISWI complex protein 0.0031 0.0104 0.0942
Echinococcus multilocularis lamin dm0 0.0054 0.0249 0.0248
Onchocerca volvulus 0.0054 0.025 0.0494
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Plasmodium vivax hypothetical protein, conserved 0.006 0.0285 0.2952
Trypanosoma cruzi protein farnesyltransferase, putative 0.0029 0.0091 0.0826
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Brugia malayi Calcium binding EGF domain containing protein 0.0065 0.0314 0.0677
Plasmodium falciparum protoporphyrinogen oxidase 0.006 0.0285 0.4881
Trypanosoma cruzi ISWI complex protein 0.0031 0.0104 0.0942
Echinococcus granulosus histone lysine methyltransferase setb 0.0135 0.0753 0.0752
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.005 0.0449
Brugia malayi EGF-like domain containing protein 0.0065 0.0314 0.0677
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Toxoplasma gondii exonuclease III APE 0.0036 0.0137 0.0262
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0137 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0022 0.0048 0.0101
Brugia malayi hypothetical protein 0.0061 0.0293 0.063
Onchocerca volvulus 0.0065 0.0314 0.0627
Onchocerca volvulus 0.0168 0.0964 0.196
Plasmodium falciparum importin beta, putative 0.002 0.0034 0.0586
Giardia lamblia Kinase, CMGC CDK 0.0026 0.0074 0.1253
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0165 0.0944 0.9698
Onchocerca volvulus 0.0054 0.025 0.0494
Brugia malayi Calcium binding EGF domain containing protein 0.0065 0.0314 0.0677
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0077 0.0393 0.0846
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0029 0.0093 0.1598
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0029 0.0091 0.1562
Echinococcus multilocularis slit 2 protein 0.0065 0.0314 0.0313
Echinococcus granulosus chromobox protein 1 0.0048 0.0206 0.0205
Toxoplasma gondii PHD-finger domain-containing protein 0.0039 0.0153 0.0294
Echinococcus multilocularis cathepsin b 0.0119 0.0654 0.0653
Plasmodium falciparum thioredoxin reductase 0.0023 0.005 0.0856
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0142
Schistosoma mansoni zinc finger protein 0.005 0.022 0.0255
Loa Loa (eye worm) hypothetical protein 0.0054 0.025 0.0537
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0042 0.0169 0.0196
Loa Loa (eye worm) heterochromatin protein 1 0.0048 0.0206 0.0443
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.006 0.0285 0.0331
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0091 0.0194
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0149 0.084 0.1196
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0038 0.0148 0.0147
Trypanosoma cruzi PAB1-binding protein , putative 0.0085 0.0441 0.4037
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0162 0.0924 0.0923
Onchocerca volvulus 0.0108 0.0584 0.118
Echinococcus granulosus beta LACTamase domain containing family member 0.0168 0.0964 0.0963
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0128 0.0711 0.071
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0023 0.005 0.0449
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0029 0.0093 0.0092
Schistosoma mansoni notch 0.0065 0.0314 0.0366
Echinococcus granulosus protein jagged 2 0.0065 0.0314 0.0313
Mycobacterium ulcerans esterase/lipase LipP 0.0168 0.0964 0.1758
Echinococcus granulosus fibropellin Ia 0.0065 0.0314 0.0313
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0404 0.2442 0.2848
Brugia malayi Cathepsin L-like precursor 0.0016 0.0009 0.0017
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0036 0.0137 0.0293
Loa Loa (eye worm) hypothetical protein 0.0026 0.0072 0.0154
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.011 0.0597 0.0596
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Leishmania major importin beta-1 subunit, putative 0.0016 0.001 0.0086
Plasmodium vivax hypothetical protein, conserved 0.006 0.0285 0.2952
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Echinococcus granulosus protein jagged 1 0.0065 0.0314 0.0313
Onchocerca volvulus 0.011 0.0597 0.1207
Trypanosoma cruzi hypothetical protein, conserved 0.0168 0.0964 0.8827
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0168 0.0964 0.1385
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.0074 0.0149
Schistosoma mansoni hypothetical protein 0.0051 0.0225 0.0262
Loa Loa (eye worm) hypothetical protein 0.011 0.0597 0.1287
Loa Loa (eye worm) hypothetical protein 0.0051 0.0225 0.0484
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0168 0.0964 0.2081
Mycobacterium tuberculosis Probable esterase LipL 0.0168 0.0964 0.1385
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Entamoeba histolytica hypothetical protein 0.007 0.035 0.5996
Onchocerca volvulus 0.0022 0.0048 0.008
Brugia malayi Cathepsin L-like precursor 0.0022 0.0048 0.0101
Echinococcus multilocularis chromobox protein 1 0.0048 0.0206 0.0205
Onchocerca volvulus 0.0794 0.4883 1
Trypanosoma cruzi trypanothione reductase, putative 0.0023 0.005 0.0449
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.0093 0.0199
Onchocerca volvulus 0.0054 0.025 0.0494
Plasmodium falciparum phd finger protein, putative 0.0039 0.0153 0.2632
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0046 0.0092
Schistosoma mansoni Lysine-specific histone demethylase 1 0.006 0.0285 0.0331
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Echinococcus multilocularis sodium bile acid cotransporter 0.0247 0.1454 0.1453
Mycobacterium ulcerans hypothetical protein 0.011 0.0597 0.1052
Loa Loa (eye worm) hypothetical protein 0.0247 0.1454 0.3138
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0048 0.0429
Plasmodium vivax importin-beta 2, putative 0.002 0.0034 0.0355
Echinococcus granulosus zinc finger protein 0.005 0.022 0.0219
Onchocerca volvulus 0.011 0.0597 0.1207
Echinococcus granulosus Tolloid protein 1 0.0077 0.0393 0.0392
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0055 0.0111
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Echinococcus granulosus sodium bile acid cotransporter 0.0247 0.1454 0.1453
Echinococcus granulosus histone acetyltransferase KAT2B 0.0388 0.2341 0.2341
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0119 0.0654 0.0762
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0036 0.0137 0.0136
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Echinococcus multilocularis protein jagged 2 0.0065 0.0314 0.0313
Brugia malayi N-terminal motif family protein 0.0126 0.07 0.1509
Toxoplasma gondii hypothetical protein 0.0054 0.025 0.0479
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0125 0.0694 0.0809
Onchocerca volvulus 0.0054 0.0249 0.0493
Loa Loa (eye worm) hypothetical protein 0.011 0.0597 0.1287
Brugia malayi Calcium binding EGF domain containing protein 0.0077 0.0393 0.0846
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) Notch2 0.0065 0.0314 0.0677
Schistosoma mansoni egf-like domain protein 0.0077 0.0393 0.0457
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Brugia malayi Trypsin family protein 0.011 0.0597 0.1287
Echinococcus granulosus peregrin 0.0054 0.0245 0.0244
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0168 0.0964 0.1124
Brugia malayi Cathepsin L-like precursor 0.0022 0.0048 0.0101
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0036 0.0137 0.0131
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Loa Loa (eye worm) hypothetical protein 0.0061 0.0293 0.063
Loa Loa (eye worm) hypothetical protein 0.0097 0.0514 0.1108
Plasmodium falciparum protein kinase 5 0.0026 0.0074 0.1268
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.005 0.0449
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0026 0.0074 0.0158
Echinococcus multilocularis cyclin dependent kinase 1 0.0026 0.0074 0.0073
Schistosoma mansoni hypothetical protein 0.0065 0.0314 0.0366
Brugia malayi Fibulin-1 precursor 0.0077 0.0393 0.0846
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.006 0.0285 0.4881
Brugia malayi Protein kinase domain containing protein 0.0026 0.0074 0.0158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Schistosoma mansoni zinc finger protein 0.0031 0.0104 0.012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0073 0.0072
Loa Loa (eye worm) PAN domain-containing protein 0.0054 0.025 0.0537
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0065 0.0317 0.0404
Schistosoma mansoni sodium-bile acid cotransporter 0.0147 0.0827 0.0964
Entamoeba histolytica hypothetical protein 0.0022 0.0049 0.0846
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0149 0.084 0.1196
Brugia malayi Kringle domain containing protein 0.0051 0.0225 0.0484
Echinococcus granulosus enteropeptidase 0.0202 0.1177 0.1176
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0137 0.2345
Onchocerca volvulus 0.0065 0.0314 0.0627
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.011 0.0597 0.0596
Giardia lamblia PHD finger protein 15 0.0039 0.0153 0.2619
Echinococcus granulosus jumonji domain containing protein 0.0054 0.0249 0.0248
Loa Loa (eye worm) acetyltransferase 0.0404 0.2442 0.5272
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0029 0.0091 0.009
Brugia malayi PHD-finger family protein 0.0039 0.0153 0.0329
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Toxoplasma gondii PAN domain-containing protein 0.0054 0.025 0.0479
Schistosoma mansoni thyroid hormone receptor 0.0175 0.1006 0.1172
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0126 0.0125
Echinococcus multilocularis Mastin 0.0202 0.1177 0.1176
Loa Loa (eye worm) hypothetical protein 0.0126 0.07 0.1509
Echinococcus multilocularis enteropeptidase 0.0202 0.1177 0.1176
Schistosoma mansoni hypothetical protein 0.0162 0.0924 0.1077
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0051 0.0228 0.0227
Mycobacterium ulcerans lipase LipD 0.0168 0.0964 0.1758
Brugia malayi beta-lactamase family protein 0.0168 0.0964 0.2081
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0535 0.1027
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0074 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0128 0.0711 0.071
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0017 0.0012 0.0025
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0046 0.0196 0.0195
Onchocerca volvulus 0.011 0.0597 0.1207
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0026 0.0074 0.0158
Echinococcus multilocularis Tolloid protein 1 0.0077 0.0393 0.0392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0014
Brugia malayi Trypsin family protein 0.011 0.0597 0.1287
Schistosoma mansoni hypothetical protein 0.007 0.035 0.0407
Schistosoma mansoni hypothetical protein 0.0042 0.0172 0.0199
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0091 0.0185
Loa Loa (eye worm) TK/ROR protein kinase 0.0051 0.0225 0.0484
Brugia malayi Pre-SET motif family protein 0.0697 0.4279 0.924
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0046 0.0092
Plasmodium vivax glutathione reductase, putative 0.0065 0.0317 0.3285
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0125 0.0694 0.0694
Entamoeba histolytica hypothetical protein 0.007 0.035 0.5996
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0036 0.0137 0.0167
Schistosoma mansoni amine oxidase 0.006 0.0285 0.0331
Brugia malayi Importin beta-1 subunit 0.002 0.0034 0.0072
Trypanosoma cruzi PAB1-binding protein , putative 0.0085 0.0441 0.4037
Giardia lamblia Prenyltransferase 0.0029 0.0091 0.1548
Trichomonas vaginalis importin beta-1, putative 0.0016 0.001 0.0019
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0049 0.0443
Echinococcus multilocularis snurportin 1 0.0214 0.1251 0.125
Brugia malayi jmjC domain containing protein 0.0128 0.0711 0.1533
Loa Loa (eye worm) hypothetical protein 0.0119 0.0654 0.141
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0149 0.084 0.8169
Plasmodium falciparum glutathione reductase 0.0065 0.0317 0.5431
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0083
Trichomonas vaginalis bromodomain-containing protein, putative 0.0122 0.0675 0.138
Loa Loa (eye worm) bromodomain containing protein 0.0046 0.0195 0.042
Echinococcus multilocularis beta LACTamase domain containing family member 0.0168 0.0964 0.0963
Brugia malayi Cathepsin L-like precursor 0.0022 0.0048 0.0101
Echinococcus granulosus geminin 0.0216 0.126 0.126
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0016 0.0009 0.0073
Plasmodium vivax basic transcription factor 3b, putative 0.0022 0.0049 0.0512
Mycobacterium leprae conserved hypothetical protein 0.0168 0.0964 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.011 0.0597 0.0695
Echinococcus granulosus laminin 0.0077 0.0393 0.0392
Schistosoma mansoni lamin 0.0054 0.0249 0.0289
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Loa Loa (eye worm) hypothetical protein 0.0054 0.025 0.0537
Plasmodium vivax vivapain-2 0.0022 0.0048 0.0496
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0367 0.0366
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0189 0.1092 1
Echinococcus granulosus cathepsin b 0.0119 0.0654 0.0653
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Schistosoma mansoni sodium-bile acid cotransporter related 0.0247 0.1454 0.1695
Onchocerca volvulus 0.0022 0.0048 0.008
Schistosoma mansoni hypothetical protein 0.0039 0.0153 0.0178
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0016 0.0009 0.0016
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0367 0.0366
Plasmodium vivax ataxin-2 like protein, putative 0.0085 0.0441 0.4578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0055 0.0111
Echinococcus multilocularis glycoprotein Antigen 5 0.0202 0.1177 0.1176
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0088 0.0162
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Loa Loa (eye worm) cysteine protease 0.0022 0.0048 0.0101
Brugia malayi EGF-like domain containing protein 0.0065 0.0314 0.0677
Brugia malayi SWIRM domain containing protein 0.006 0.0285 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0027 0.0053
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0036 0.0137 0.0136
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.005 0.0449
Echinococcus granulosus microtubule associated protein 2 0.1382 0.8572 0.8572
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Onchocerca volvulus Neurogenic locus notch homolog 0.0065 0.0314 0.0627
Giardia lamblia NADH oxidase lateral transfer candidate 0.0023 0.005 0.0841
Loa Loa (eye worm) hypothetical protein 0.0077 0.0393 0.0846
Onchocerca volvulus 0.0022 0.0048 0.008
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0214 0.1251 0.2699
Toxoplasma gondii target of rapamycin (TOR), putative 0.0022 0.0046 0.0088
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0027 0.0075 0.0677
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0249 0.0536
Echinococcus multilocularis lysine specific histone demethylase 1A 0.006 0.0285 0.0284
Giardia lamblia Kinase, CMGC CDK 0.0026 0.0074 0.1253
Echinococcus granulosus cathepsin l1 0.0022 0.0048 0.0047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0135 0.0753 0.0877
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0135 0.0753 0.0877
Schistosoma mansoni thyroid hormone receptor 0.0175 0.1006 0.1172
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0036 0.0137 1
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0792 0.4874 0.7305
Schistosoma mansoni importin beta-1 0.002 0.0034 0.0039
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0168 0.0964 0.1385
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0032 0.0064
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0048 0.0055
Toxoplasma gondii microneme protein MIC17B 0.0054 0.025 0.0479
Mycobacterium ulcerans oxidoreductase 0.006 0.0285 0.0451
Trypanosoma cruzi cdc2-related kinase 3 0.0026 0.0074 0.0669
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0036 0.0137 0.2332
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Trypanosoma cruzi trypanothione reductase, putative 0.0065 0.0317 0.2894
Loa Loa (eye worm) hypothetical protein 0.011 0.0597 0.1287
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0029 0.0093 0.0845
Brugia malayi EGF-like domain containing protein 0.0065 0.0314 0.0677
Brugia malayi beta-NAC-like protein 0.0022 0.0049 0.0104
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0029 0.0091 0.0105
Plasmodium falciparum histone acetyltransferase GCN5 0.0108 0.0583 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0014
Echinococcus multilocularis thioredoxin glutathione reductase 0.0065 0.0317 0.0316
Echinococcus granulosus neurogenic locus notch protein 0.0065 0.0314 0.0313
Loa Loa (eye worm) hypothetical protein 0.006 0.0285 0.0613
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0017
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0046 0.0196 0.0228
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0023 0.005 0.0449
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0023 0.0056 0.05
Toxoplasma gondii microneme protein MIC4 0.0054 0.025 0.0479
Toxoplasma gondii hypothetical protein 0.003 0.0099 0.0191
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Loa Loa (eye worm) trypsin family protein 0.011 0.0597 0.1287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0055 0.0111
Loa Loa (eye worm) hypothetical protein 0.0061 0.0293 0.063
Schistosoma mansoni intermediate filament proteins 0.0054 0.0249 0.0289
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0088 0.0178
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0023 0.005 0.0518
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Giardia lamblia High cysteine protein 0.0065 0.0314 0.5381
Toxoplasma gondii EGF family domain-containing protein 0.0065 0.0314 0.0603
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.006 0.0285 0.4881
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0206 0.042
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Echinococcus granulosus cathepsin b 0.0119 0.0654 0.0653
Toxoplasma gondii PAN domain-containing protein 0.0846 0.5212 1
Loa Loa (eye worm) PAN domain-containing protein 0.0054 0.025 0.0537
Trypanosoma brucei transcription factor BTF3, putative 0.0022 0.0049 0.0443
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0018 0.0034
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0249 0.0536
Schistosoma mansoni notch 0.0065 0.0314 0.0366
Schistosoma mansoni notch 0.0065 0.0314 0.0366
Trypanosoma cruzi cdc2-related kinase 1 0.0026 0.0074 0.0669
Trichomonas vaginalis mercuric reductase, putative 0.0023 0.005 0.01
Echinococcus multilocularis neurogenic locus notch protein 0.0065 0.0314 0.0313
Brugia malayi Cadherin domain containing protein 0.0065 0.0314 0.0677
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0108 0.0584 0.068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0753 0.4631 1
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Loa Loa (eye worm) PAN domain-containing protein 0.0054 0.025 0.0537
Loa Loa (eye worm) hypothetical protein 0.0054 0.025 0.0537
Loa Loa (eye worm) PAN domain-containing protein 0.0054 0.025 0.0537
Loa Loa (eye worm) hypothetical protein 0.0077 0.0393 0.0846
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0048 0.082
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0027 0.0053
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0029 0.0093 0.0108
Toxoplasma gondii PAN domain-containing protein 0.0054 0.025 0.0479
Loa Loa (eye worm) hypothetical protein 0.006 0.0285 0.0613
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0029 0.0093 0.0845
Schistosoma mansoni memapsin-2 (A01 family) 0.0251 0.1484 0.1731
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0077 0.0393 0.0846
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0077 0.0393 0.0846
Loa Loa (eye worm) cathepsin B 0.0042 0.0169 0.0363
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.011 0.0597 0.0596
Trichomonas vaginalis CMGC family protein kinase 0.0026 0.0074 0.0149
Echinococcus granulosus transcription factor btf3 0.0022 0.0049 0.0048
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0042 0.0169 0.154
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0048 0.0429
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Schistosoma mansoni hypothetical protein 0.0214 0.1251 0.1458
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0015 0.0001 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0075 0.0161
Brugia malayi Sodium Bile acid symporter family protein 0.0247 0.1454 0.3138
Brugia malayi Heterochromatin protein 1 0.0048 0.0206 0.0443
Loa Loa (eye worm) hypothetical protein 0.0135 0.0753 0.1624
Echinococcus granulosus Mastin 0.0202 0.1177 0.1176
Loa Loa (eye worm) hypothetical protein 0.0026 0.0073 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Onchocerca volvulus 0.0054 0.025 0.0494
Echinococcus granulosus cyclin dependent kinase 0.0026 0.0074 0.0073
Loa Loa (eye worm) ctsf protein 0.0022 0.0048 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Echinococcus granulosus cathepsin l cysteine peptidase 0.0022 0.0048 0.0047
Toxoplasma gondii NAC domain-containing protein 0.0022 0.0049 0.0095
Echinococcus granulosus lamin dm0 0.0054 0.0249 0.0248
Loa Loa (eye worm) beta-lactamase 0.0168 0.0964 0.2081
Schistosoma mansoni notch 0.0065 0.0314 0.0366
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0029 0.0091 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0168 0.0964 0.8827
Schistosoma mansoni jumonji/arid domain-containing protein 0.0051 0.0229 0.0267
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0009 0.0153
Schistosoma mansoni eyes absent homolog 0.0061 0.0293 0.034
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Toxoplasma gondii LsmAD domain-containing protein 0.0085 0.0441 0.0847
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0015
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0036 0.0076
Mycobacterium tuberculosis Conserved protein 0.0168 0.0964 0.1385
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0029 0.0093 0.0845
Toxoplasma gondii subtilisin SUB12 0.0054 0.025 0.0479
Plasmodium falciparum cysteine repeat modular protein 1 0.0051 0.0225 0.3861
Schistosoma mansoni hypothetical protein 0.0065 0.0314 0.0366
Brugia malayi Delta serrate ligand family protein 0.0065 0.0314 0.0677
Echinococcus multilocularis transmembrane protease serine 3 0.011 0.0597 0.0596
Echinococcus granulosus cathepsin l1 0.0016 0.0009 0.0008
Mycobacterium tuberculosis Probable reductase 0.0149 0.084 0.1196
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0026 0.0074 0.0669
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0119 0.0654 0.5984
Entamoeba histolytica cysteine protease, putative 0.0022 0.0048 0.082
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0049 0.0099
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0026 0.0074 0.0158
Plasmodium falciparum ataxin-2 like protein, putative 0.0085 0.0441 0.757
Loa Loa (eye worm) hypothetical protein 0.0054 0.025 0.0537
Loa Loa (eye worm) jmjC domain-containing protein 0.0081 0.0414 0.0893
Loa Loa (eye worm) hypothetical protein 0.0077 0.0393 0.0846
Brugia malayi cathepsin L-like precursor 0.0016 0.0009 0.0017
Schistosoma mansoni chromobox protein 0.0048 0.0206 0.0239
Leishmania major mitochondrial DNA polymerase beta 0.0189 0.1092 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0023 0.005 0.0106
Echinococcus granulosus lysine specific histone demethylase 1A 0.006 0.0285 0.0284
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0096 0.0512 0.0511
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Onchocerca volvulus 0.0022 0.0048 0.008
Mycobacterium leprae Probable lipase LipE 0.0168 0.0964 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0202 0.1177 0.1372
Plasmodium vivax hypothetical protein, conserved 0.0168 0.0964 1
Loa Loa (eye worm) PHD-finger family protein 0.0039 0.0153 0.0329
Schistosoma mansoni microtubule-associated protein tau 0.1382 0.8572 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0039 0.0153 0.0153
Onchocerca volvulus Putative cubilin 0.0065 0.0314 0.0627
Trypanosoma cruzi transcription factor btf3, putative 0.0022 0.0049 0.0443
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0065 0.0314 0.0366
Brugia malayi EGF-like domain containing protein 0.0065 0.0314 0.0677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0009 0.0016
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.011 0.0597 0.0596
Trypanosoma cruzi UDP-galactopyranose mutase 0.006 0.0285 0.2599
Loa Loa (eye worm) hypothetical protein 0.0077 0.0393 0.0846
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0026 0.0074 0.0142
Toxoplasma gondii histone lysine methyltransferase SET1 0.0018 0.0023 0.0044
Loa Loa (eye worm) hypothetical protein 0.0054 0.025 0.0537
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Trypanosoma brucei PAB1-binding protein , putative 0.0085 0.0441 0.4037
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0753 0.4631 0.5402
Schistosoma mansoni laminin gamma-3 chain 0.0065 0.0314 0.0366
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.0048 0.0429
Mycobacterium tuberculosis Probable lipase LipE 0.0168 0.0964 0.1385
Entamoeba histolytica transcription factor BTF3, putative 0.0022 0.0049 0.0846
Brugia malayi Cathepsin L-like precursor 0.0022 0.0048 0.0101
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0026 0.0074 0.0073
Brugia malayi beta-lactamase 0.0168 0.0964 0.2081
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0165 0.0944 0.1353
Mycobacterium tuberculosis Conserved hypothetical protein 0.0099 0.0532 0.073
Echinococcus multilocularis lysine specific demethylase 5A 0.0047 0.0205 0.0204
Echinococcus granulosus chromobox protein 1 0.0048 0.0206 0.0205
Onchocerca volvulus 0.0236 0.1386 0.2825
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0118 0.0649 0.1399
Brugia malayi Pre-SET motif family protein 0.01 0.0535 0.1154
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0023 0.005 0.0518
Schistosoma mansoni bromodomain containing protein 0.0139 0.0778 0.0906
Entamoeba histolytica hypothetical protein 0.0016 0.001 0.0179
Leishmania major hypothetical protein, conserved 0.0051 0.0225 0.2055
Brugia malayi Calcium binding EGF domain containing protein 0.0065 0.0314 0.0677
Echinococcus granulosus neurogenic locus notch protein 4 0.0065 0.0314 0.0313
Trichomonas vaginalis penicillin-binding protein, putative 0.0168 0.0964 0.1973
Echinococcus multilocularis cysteine protease 0.0022 0.0048 0.0047
Echinococcus multilocularis sodium bile acid cotransporter 0.0247 0.1454 0.1453
Plasmodium falciparum basic transcription factor 3b, putative 0.0022 0.0049 0.0846
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0065 0.0314 0.0627
Echinococcus multilocularis notch 0.0065 0.0314 0.0313
Trypanosoma cruzi cdc2-related kinase 1 0.0026 0.0074 0.0669
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0535 0.0534
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0125 0.0694 0.1498
Trypanosoma brucei ISWI complex protein 0.0031 0.0104 0.0942
Brugia malayi intermediate filament protein 0.0054 0.0249 0.0536
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0753 0.4631 0.5402
Schistosoma mansoni jumonji/arid domain-containing protein 0.0051 0.0229 0.0267
Toxoplasma gondii microneme protein MIC17A 0.0054 0.025 0.0479
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0131 0.0732 0.0731
Chlamydia trachomatis protoporphyrinogen oxidase 0.006 0.0285 1
Brugia malayi cathepsin B-like cysteine proteinase 0.0119 0.0654 0.141
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0029 0.0091 0.0826
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Loa Loa (eye worm) hypothetical protein 0.0168 0.0964 0.2081
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0142
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0122 0.0675 0.6998
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0023 0.005 0.0856
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0022 0.0048 0.0096
Echinococcus multilocularis jumonji domain containing protein 0.0054 0.0249 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0236 0.1386 0.299
Onchocerca volvulus 0.0388 0.2341 0.4785
Leishmania major hypothetical protein, conserved 0.0168 0.0964 0.8827
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0075 0.0152
Mycobacterium tuberculosis Probable lipase LipD 0.0168 0.0964 0.1385
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Toxoplasma gondii HEAT repeat-containing protein 0.002 0.0034 0.0066
Onchocerca volvulus 0.0644 0.3942 0.8071
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0125 0.0694 0.1498
Leishmania major trypanothione reductase 0.0065 0.0317 0.2894
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0037
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0022 0.0048 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Entamoeba histolytica acetyltransferase, GNAT family 0.0108 0.0583 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.035 0.0349
Echinococcus multilocularis musashi 0.0054 0.0249 0.0248
Onchocerca volvulus Cathepsin L homolog 0.0022 0.0048 0.008
Mycobacterium tuberculosis Probable oxidoreductase 0.0165 0.0944 0.1353
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0036 0.0137 0.1244
Schistosoma mansoni lamin 0.0054 0.0249 0.0289
Loa Loa (eye worm) hypothetical protein 0.0078 0.0398 0.0858
Loa Loa (eye worm) hypothetical protein 0.0168 0.0964 0.2081
Trichomonas vaginalis penicillin-binding protein, putative 0.0168 0.0964 0.1973
Schistosoma mansoni notch 0.0065 0.0314 0.0366
Loa Loa (eye worm) hypothetical protein 0.0067 0.0329 0.0707
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.001 0.0019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0024 0.006 0.0069
Trichomonas vaginalis D-aminoacylase, putative 0.0168 0.0964 0.1973
Brugia malayi glutathione reductase 0.0065 0.0317 0.0682
Schistosoma mansoni slit 0.0065 0.0314 0.0366
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0075 0.0677
Loa Loa (eye worm) notch protein 0.0065 0.0314 0.0677
Echinococcus multilocularis neural cadherin 0.0065 0.0314 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0093 0.0189
Mycobacterium tuberculosis Probable hydrolase 0.0168 0.0964 0.1385
Onchocerca volvulus 0.0022 0.0048 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0093 0.0189
Echinococcus granulosus lysine specific histone demethylase 1A 0.006 0.0285 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0049 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0015
Plasmodium falciparum thioredoxin reductase 0.0065 0.0317 0.5431
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0048 0.082
Mycobacterium ulcerans hypothetical protein 0.0099 0.0532 0.0927
Schistosoma mansoni bromodomain containing protein 0.0018 0.0024 0.0027
Echinococcus multilocularis cathepsin L cysteine protease 0.0022 0.0048 0.0047
Leishmania major lanosterol synthase, putative 0.0024 0.0059 0.0534
Giardia lamblia Cathepsin B precursor 0.0042 0.0169 0.2886
Plasmodium falciparum cysteine proteinase falcipain 3 0.0022 0.0048 0.082
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0126 0.0125
Toxoplasma gondii hypothetical protein 0.0054 0.025 0.0479
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.005 0.0449
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0026
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0119 0.0654 0.0762
Treponema pallidum exodeoxyribonuclease (exoA) 0.0036 0.0137 1
Brugia malayi hypothetical protein 0.0085 0.0441 0.0951
Loa Loa (eye worm) hypothetical protein 0.0054 0.0249 0.0536
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0012 0.0012
Trypanosoma cruzi lanosterol synthase, putative 0.0032 0.0109 0.0988
Schistosoma mansoni hypothetical protein 0.0065 0.0314 0.0366
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0101
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0036 0.0137 0.1244
Echinococcus granulosus slit 2 protein 0.0065 0.0314 0.0313
Schistosoma mansoni sodium-bile acid cotransporter related 0.01 0.0535 0.0623
Loa Loa (eye worm) hypothetical protein 0.0054 0.025 0.0537
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.035 0.0349
Onchocerca volvulus 0.0054 0.025 0.0494
Toxoplasma gondii thioredoxin reductase 0.0065 0.0317 0.0608
Plasmodium vivax protoporphyrinogen oxidase, putative 0.006 0.0285 0.2952
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0048 0.0101
Trichomonas vaginalis esterase, putative 0.0168 0.0964 0.1973
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0036 0.0137 0.1244
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0023 0.005 0.0096
Echinococcus multilocularis sodium bile acid cotransporter 0.0247 0.1454 0.1453
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0023 0.005 0.0856
Mycobacterium ulcerans beta-lactamase 0.0168 0.0964 0.1758
Brugia malayi SH2 domain containing protein 0.02 0.1162 0.2508
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0153 0.1592
Schistosoma mansoni hypothetical protein 0.0065 0.0314 0.0366
Trypanosoma brucei cdc2-related kinase 1 0.0026 0.0074 0.0669
Giardia lamblia Histone acetyltransferase GCN5 0.0108 0.0583 1
Schistosoma mansoni hypothetical protein 0.0216 0.126 0.1469
Echinococcus granulosus transmembrane protease serine 3 0.011 0.0597 0.0596
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Echinococcus granulosus snurportin 1 0.0214 0.1251 0.125
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0023 0.0056 0.05
Echinococcus multilocularis cyclin dependent kinase 0.0026 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0118 0.0649 0.1399
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Onchocerca volvulus 0.0054 0.025 0.0494
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0029 0.0093 0.0845
Echinococcus granulosus importin subunit beta 1 0.002 0.0034 0.0033
Onchocerca volvulus 0.0065 0.0314 0.0627
Plasmodium vivax vivapain-2 0.0022 0.0048 0.0496
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0535 0.0623
Plasmodium vivax thioredoxin reductase, putative 0.0065 0.0317 0.3285
Trichomonas vaginalis glutathione reductase, putative 0.0023 0.005 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Echinococcus multilocularis tissue type plasminogen activator 0.0051 0.0225 0.0224
Trypanosoma brucei cysteine peptidase C (CPC) 0.0042 0.0169 0.154
Onchocerca volvulus 0.0054 0.025 0.0494
Toxoplasma gondii microneme protein MIC17C 0.0054 0.025 0.0479
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.011 0.0597 0.0695
Onchocerca volvulus 0.0054 0.025 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0046 0.0092
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0206 0.042
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0021 0.0042 0.0431
Echinococcus multilocularis neurogenic locus protein delta 0.0065 0.0314 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0046 0.0092
Onchocerca volvulus Slit protein homolog 0.0065 0.0314 0.0627
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0029 0.0091 0.0185
Echinococcus multilocularis neurogenic locus notch protein 0.0065 0.0314 0.0313
Schistosoma mansoni hypothetical protein 0.0031 0.0104 0.012
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0168 0.0964 0.2081
Brugia malayi Cathepsin L-like precursor 0.0022 0.0048 0.0101
Onchocerca volvulus 0.0247 0.1454 0.2965
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0225 0.2055
Echinococcus granulosus fetal alzheimer antigen falz 0.0046 0.0196 0.0195
Toxoplasma gondii PAN domain-containing protein 0.0054 0.025 0.0479
Loa Loa (eye worm) glutathione reductase 0.0065 0.0317 0.0682
Echinococcus granulosus protein jagged 1 0.0065 0.0314 0.0313
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.011 0.0597 0.0695
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0051 0.0225 0.2335
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0089 0.0469 0.4286
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0048 0.0429
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0029 0.0091 0.0195
Loa Loa (eye worm) hypothetical protein 0.0168 0.0964 0.2081
Trypanosoma cruzi cdc2-related kinase 3 0.0026 0.0074 0.0669
Brugia malayi RNA, U transporter 1 0.0057 0.0266 0.0572
Mycobacterium tuberculosis Conserved protein 0.0168 0.0964 0.1385
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0051
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0075 0.0677
Trichomonas vaginalis set domain proteins, putative 0.0794 0.4883 1
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0065 0.0314 0.0677
Brugia malayi cell division control protein 2 homolog 0.0026 0.0074 0.0158
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0051 0.0228 0.0227
Echinococcus multilocularis cyclin dependent kinase 1 0.0026 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0085 0.0441 0.0951
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Echinococcus multilocularis tumor protein p63 0.161 1 1
Toxoplasma gondii histone lysine-specific demethylase 0.006 0.0285 0.0546
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0088 0.0178
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0023 0.005 0.0449
Brugia malayi Muscle positioning protein 4 0.0065 0.0314 0.0677
Trypanosoma cruzi importin beta-1 subunit, putative 0.0016 0.001 0.0086
Loa Loa (eye worm) phosphatidylinositol 3 0.0029 0.0093 0.0199
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0165 0.0944 0.1353
Echinococcus multilocularis neurogenic locus protein delta 0.0065 0.0314 0.0313
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.006 0.0285 0.0546
Echinococcus multilocularis zinc finger protein 0.005 0.022 0.0219
Onchocerca volvulus 0.0753 0.4631 0.9484
Schistosoma mansoni ap endonuclease 0.0036 0.0137 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0046 0.0092
Onchocerca volvulus 0.0054 0.025 0.0494
Echinococcus granulosus sodium bile acid cotransporter 0.0247 0.1454 0.1453
Echinococcus multilocularis cyclin dependent kinase 5 0.0026 0.0074 0.0073
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0009 0.0009
Giardia lamblia GTOR 0.0029 0.0093 0.1584
Brugia malayi Papain family cysteine protease containing protein 0.0022 0.0048 0.0101
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0122 0.0675 0.1295
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0029 0.0093 0.0845
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0022 0.0048 0.0047
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0048 0.0055
Entamoeba histolytica hypothetical protein 0.007 0.035 0.5996
Loa Loa (eye worm) jmjC domain-containing protein 0.0051 0.0229 0.0493
Brugia malayi Cathepsin L-like cysteine proteinase 0.0016 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.006 0.0285 0.0613
Toxoplasma gondii calcium binding egf domain-containing protein 0.0077 0.0393 0.0753
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0015 0.0001 0.0002
Brugia malayi Bromodomain containing protein 0.0088 0.0459 0.0989
Loa Loa (eye worm) fibroinase 0.0022 0.0048 0.0101
Brugia malayi exodeoxyribonuclease III family protein 0.0036 0.0137 0.0293
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0404 0.2442 0.2441
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Brugia malayi Trypsin-like protease protein 5 0.011 0.0597 0.1287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Trypanosoma brucei hypothetical protein, conserved 0.0168 0.0964 0.8827
Schistosoma mansoni hypothetical protein 0.0048 0.0209 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.0038 0.0148 0.0171
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0042 0.0169 0.154
Schistosoma mansoni septate junction protein 0.0065 0.0314 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Leishmania major UDP-galactopyranose mutase 0.006 0.0285 0.2599
Onchocerca volvulus 0.0051 0.0225 0.0444
Onchocerca volvulus 0.011 0.0597 0.1207
Loa Loa (eye worm) ICD-1 protein 0.0022 0.0049 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Echinococcus multilocularis cysteine protease 0.0022 0.0048 0.0047
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0077 0.0393 0.0846
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0048 0.0096
Brugia malayi Cathepsin L-like precursor 0.0016 0.0009 0.0017
Echinococcus granulosus cathepsin L cysteine proteinase 0.0022 0.0048 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0028 0.0056
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0032 0.0109 0.0089
Brugia malayi chromobox protein homolog 3 0.0027 0.0075 0.0161
Onchocerca volvulus 0.0054 0.025 0.0494
Brugia malayi Cathepsin L-like precursor 0.0022 0.0048 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0008 0.0014
Echinococcus multilocularis fibropellin Ia 0.0065 0.0314 0.0313
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0029 0.0091 0.0945
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0054 0.025 0.0479
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0077 0.0393 0.0457
Brugia malayi Bromodomain containing protein 0.0163 0.0927 0.2
Leishmania major cathepsin L-like protease 0.0022 0.0048 0.0429
Brugia malayi acetyltransferase, GNAT family protein 0.0404 0.2442 0.5272
Brugia malayi Bromodomain containing protein 0.0054 0.0245 0.0527
Mycobacterium ulcerans dehydrogenase 0.006 0.0285 0.0451
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0126 0.07 0.1418
Echinococcus multilocularis importin subunit beta 1 0.002 0.0034 0.0033
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1076 0.6654 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0285 0.0613
Echinococcus granulosus expressed conserved protein 0.0048 0.0209 0.0208
Loa Loa (eye worm) hypothetical protein 0.0118 0.0649 0.1399
Loa Loa (eye worm) hypothetical protein 0.0144 0.0811 0.175
Trypanosoma cruzi cruzipain precursor, putative 0.0022 0.0048 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0018 0.0034
Loa Loa (eye worm) thioredoxin reductase 0.0065 0.0317 0.0682
Brugia malayi Protein kinase domain containing protein 0.0051 0.0225 0.0484
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0189 0.1092 1
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0029 0.0091 0.0195
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.011 0.0597 0.1287
Trypanosoma brucei trypanothione reductase 0.0065 0.0317 0.2894
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0017 0.0012 0.0025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0125 0.0694 0.0694
Loa Loa (eye worm) hypothetical protein 0.0065 0.0314 0.0677
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0249 0.0536
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0055 0.0111
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0126 0.0146
Brugia malayi PAN domain containing protein 0.0054 0.025 0.0537
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0125 0.0694 0.0809
Echinococcus multilocularis chromobox protein 1 0.0048 0.0206 0.0205
Schistosoma mansoni cercarial elastase (S01 family) 0.011 0.0597 0.0695
Leishmania major hypothetical protein, conserved 0.0085 0.0441 0.4037
Schistosoma mansoni hypothetical protein 0.0065 0.0314 0.0366
Schistosoma mansoni ap endonuclease 0.0036 0.0137 0.0158
Entamoeba histolytica cell division protein kinase 2, putative 0.0026 0.0074 0.1268
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0034 0.0304
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0852 0.5251 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.025 0.0537
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0149 0.084 0.1196
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0022 0.0048 0.0096
Toxoplasma gondii PAN domain-containing protein 0.0054 0.025 0.0479
Brugia malayi amine oxidase, flavin-containing family protein 0.006 0.0285 0.0613
Onchocerca volvulus Arrow homolog 0.0077 0.0393 0.0787
Mycobacterium ulcerans protoporphyrinogen oxidase 0.006 0.0285 0.0451
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0137 0.0278

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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