Detailed information for compound 1036946

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 221.645 | Formula: C6H12ClN5O2
  • H donors: 3 H acceptors: 5 LogP: -2.23 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(CCCc1nnn[nH]1)N.Cl
  • InChi: 1S/C6H11N5O2.ClH/c7-4(6(12)13)2-1-3-5-8-10-11-9-5;/h4H,1-3,7H2,(H,12,13)(H,8,9,10,11);1H
  • InChiKey: BKVFTCLDKGOFAH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 No references
Homo sapiens glutamate receptor, ionotropic, N-methyl-D-aspartate 3B No references
Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2A No references
Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2B No references
Homo sapiens glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis nmda type glutamate receptor Get druggable targets OG5_133478 All targets in OG5_133478
Schistosoma japonicum Glutamate [NMDA] receptor subunit zeta-1 precursor, putative Get druggable targets OG5_133478 All targets in OG5_133478
Echinococcus granulosus glutamate NMDA receptor subunit Get druggable targets OG5_129290 All targets in OG5_129290
Echinococcus multilocularis glutamate (NMDA) receptor subunit Get druggable targets OG5_129290 All targets in OG5_129290
Schistosoma mansoni glutamate receptor NMDA Get druggable targets OG5_133478 All targets in OG5_133478
Schistosoma mansoni glutamate receptor NMDA Get druggable targets OG5_129290 All targets in OG5_129290
Echinococcus granulosus nmda type glutamate receptor Get druggable targets OG5_133478 All targets in OG5_133478
Schistosoma japonicum expressed protein Get druggable targets OG5_133478 All targets in OG5_133478
Echinococcus granulosus glutamate receptor NMDA Get druggable targets OG5_133478 All targets in OG5_133478
Echinococcus multilocularis nmda type glutamate receptor Get druggable targets OG5_133478 All targets in OG5_133478
Echinococcus multilocularis glutamate receptor NMDA Get druggable targets OG5_133478 All targets in OG5_133478
Schistosoma japonicum ko:K05314 glutamate receptor, ionotropic, N-methyl-D-aspartate 2, invertebrate, putative Get druggable targets OG5_129290 All targets in OG5_129290
Schistosoma japonicum Glutamate [NMDA] receptor subunit zeta-1 precursor, putative Get druggable targets OG5_133478 All targets in OG5_133478
Schistosoma japonicum Glutamate [NMDA] receptor subunit zeta-1 precursor, putative Get druggable targets OG5_133478 All targets in OG5_133478
Echinococcus granulosus nmda type glutamate receptor Get druggable targets OG5_133478 All targets in OG5_133478
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis musashi 0.0059 0.0067 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0193 0.8147
Schistosoma mansoni hypothetical protein 0.0872 0.1236 0.2858
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Echinococcus multilocularis FTZ F1 alpha 0.0044 0.0045 0.0104
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.0006 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0098 0.0123 0.1334
Echinococcus granulosus flap endonuclease GEN 1 0.0017 0.0006 0.0014
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0017 0.0006 0.0015
Plasmodium falciparum DNA repair protein RAD2, putative 0.0017 0.0006 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0044 0.0045 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0034
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0082 0.01 0.0231
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.0413 0.2628
Echinococcus granulosus bloom syndrome protein 0.0117 0.015 0.0346
Entamoeba histolytica hypothetical protein 0.0194 0.0261 0.1653
Schistosoma mansoni hypothetical protein 0.0314 0.0434 0.1003
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0052 0.0121
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.029 0.3131
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0167 0.0223 0.0514
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0122 0.29
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0044 0.0045 0.0486
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0072 0.0085 0.0307
Onchocerca volvulus Putative neutral sphingomyelinase 0.0017 0.0006 0.0006
Loa Loa (eye worm) transcription factor SMAD2 0.0515 0.0722 0.7807
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0062 0.0144
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0052 0.0121
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1903 0.2718 1
Onchocerca volvulus Bile acid receptor homolog 0.0044 0.0045 0.0045
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0194 0.0261 0.0602
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0017 0.0489
Giardia lamblia Telomerase catalytic subunit 0.1903 0.2718 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.029 0.0399
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.0122 0.0122
Entamoeba histolytica hypothetical protein 0.0314 0.0433 0.2755
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0013 0.0138
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0036 0.011
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0011 0.006
Brugia malayi BRM protein 0.0143 0.0188 0.0259
Brugia malayi nuclear receptor NHR-67 0.0021 0.0012 0.0016
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0017 0.0006 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0045 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0044 0.0045 0.0062
Schistosoma mansoni ran 0.0022 0.0013 0.0031
Echinococcus multilocularis NMDA receptor 0.0057 0.0064 0.0147
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0015 0.0035
Onchocerca volvulus 0.0278 0.0382 0.0382
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0007 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0249
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0012 0.0127
Brugia malayi Importin beta-1 subunit 0.0061 0.007 0.0097
Echinococcus multilocularis BRK domain containing protein 0.0025 0.0018 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Schistosoma mansoni terminal deoxycytidyl transferase 0.0096 0.012 0.0278
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0015 0.0035
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0083 0.0101 0.035
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0012 0.0027
Echinococcus granulosus GPCR family 2 0.0068 0.0079 0.0184
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0034
Trichomonas vaginalis set domain proteins, putative 0.0278 0.0382 0.9167
Loa Loa (eye worm) fli-1 protein 0.0238 0.0325 0.3512
Brugia malayi Receptor family ligand binding region containing protein 0.0014 0.0002 0.0003
Echinococcus granulosus dna polymerase eta 0.0123 0.0158 0.0366
Echinococcus multilocularis BRK domain containing protein 0.0025 0.0018 0.0041
Brugia malayi MH1 domain containing protein 0.0035 0.0033 0.0045
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0036 0.0034 0.0117
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0012 0.0016
Echinococcus multilocularis GPCR, family 2 0.0068 0.0079 0.0184
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0017 0.0321
Trypanosoma brucei DNA polymerase IV, putative 0.0124 0.016 0.0568
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0012 0.0027
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0096 0.012 0.1301
Brugia malayi mbt repeat family protein 0.0049 0.0052 0.0072
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0012 0.0027
Giardia lamblia DINP protein human, muc B family 0.0103 0.013 0.0458
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0017 0.0006 0.0093
Echinococcus granulosus dnaJ subfamily B 0.0872 0.1236 0.2858
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.0006 0.01
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0122 0.29
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0005 0.005
Echinococcus multilocularis Smad4 0.0035 0.0033 0.0075
Plasmodium vivax importin-beta 2, putative 0.0061 0.007 0.0259
Loa Loa (eye worm) glutaminase 2 0.0302 0.0417 0.4504
Schistosoma mansoni protein kinase 0.0014 0.0002 0.0004
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0167 0.0223 0.0514
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Brugia malayi nuclear hormone receptor 0.0044 0.0045 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0044 0.0045 0.0062
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0017 0.0006 0.0014
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0017 0.0006 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0045 0.0104
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0017 0.0097
Brugia malayi N-terminal motif family protein 0.0185 0.0249 0.0342
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0017 0.0006 0.0063
Loa Loa (eye worm) ATP-dependent DNA helicase 0.006 0.0069 0.0741
Echinococcus granulosus Smad4 0.0035 0.0033 0.0075
Schistosoma mansoni Smad4 0.0035 0.0033 0.0075
Onchocerca volvulus 0.0098 0.0123 0.0123
Trypanosoma cruzi DNA polymerase kappa, putative 0.0124 0.016 0.0582
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.0413 0.2628
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0017 0.0006 0.0093
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0012 0.0027
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0025 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0007 0.004
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0012 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0036 0.0082
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0018 0.0024
Brugia malayi Disco-interacting protein 2 homolog 0.0043 0.0043 0.006
Trypanosoma brucei unspecified product 0.0117 0.015 0.0532
Schistosoma mansoni zinc finger protein 0.0021 0.0012 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0096 0.012 0.4996
Echinococcus multilocularis geminin 0.075 0.106 0.2451
Loa Loa (eye worm) hypothetical protein 0.0043 0.0043 0.0468
Entamoeba histolytica recQ family helicase, putative 0.0029 0.0024 0.0144
Giardia lamblia Flap structure-specific endonuclease 0.0083 0.0101 0.035
Treponema pallidum fructose-bisphosphate aldolase 0.03 0.0413 1
Leishmania major hypothetical protein, conserved 0.0017 0.0006 0.0015
Leishmania major RNA-editing complex protein MP100, putative 0.0017 0.0006 0.0015
Brugia malayi MH2 domain containing protein 0.0035 0.0033 0.0045
Loa Loa (eye worm) hypothetical protein 0.0037 0.0036 0.0385
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0067 0.0724
Brugia malayi Flap endonuclease-1 0.0083 0.0101 0.0139
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0036 0.0034 0.0102
Toxoplasma gondii RNA-directed DNA polymerase 0.1903 0.2718 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Schistosoma mansoni helicase 0.0143 0.0188 0.0435
Mycobacterium tuberculosis Conserved hypothetical protein 0.0176 0.0235 1
Brugia malayi TAR-binding protein 0.0066 0.0076 0.0105
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0017 0.0006 0.0016
Loa Loa (eye worm) BRM protein 0.0074 0.0089 0.0957
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Schistosoma mansoni lamin 0.0059 0.0067 0.0155
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0223
Toxoplasma gondii histone lysine methyltransferase SET1 0.0122 0.0158 0.056
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0017 0.0006 0.0014
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0017 0.0006 0.0063
Entamoeba histolytica Ran family GTPase 0.0022 0.0013 0.0073
Schistosoma mansoni DNA helicase recq1 0.006 0.0069 0.0158
Brugia malayi metabotropic glutamate receptor type 2 0.0014 0.0002 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0044 0.0045 0.0486
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0025 0.007
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Loa Loa (eye worm) hypothetical protein 0.0455 0.0636 0.6874
Onchocerca volvulus 0.0014 0.0002 0.0002
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0209 0.0764
Brugia malayi nuclear receptor RXR 0.0021 0.0012 0.0016
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.0122 0.0283
Loa Loa (eye worm) runx1 0.0057 0.0064 0.0693
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0036 0.0082
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0072 0.0085 0.0307
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0105 0.0133 0.0489
Echinococcus multilocularis ecdysone induced protein 78C 0.0044 0.0045 0.0104
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.0006 0.0001
Loa Loa (eye worm) RGC/RGC protein kinase 0.0014 0.0002 0.002
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0011 0.0223
Echinococcus multilocularis peregrin 0.0014 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0067
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0045 0.0104
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.0033 0.0075
Trichomonas vaginalis glutaminase, putative 0.0302 0.0417 1
Plasmodium falciparum DEAD/DEAH box helicase, putative 0.0022 0.0014 0.0052
Schistosoma mansoni SET domain protein 0.0017 0.0007 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0044 0.0045 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Echinococcus multilocularis glutamate receptor NMDA 0.0095 0.0119 0.0275
Brugia malayi Fli-1 protein 0.0238 0.0325 0.0447
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0066 0.0223
Mycobacterium ulcerans hypothetical protein 0.0176 0.0235 0.5552
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0083 0.0101 0.0364
Echinococcus multilocularis exonuclease 1 0.0017 0.0006 0.0014
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0066 0.0153
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0121 0.028
Loa Loa (eye worm) DR-78 0.0021 0.0012 0.0127
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0054 0.1247
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0079 0.0109
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0014
Echinococcus granulosus smad 0.0035 0.0033 0.0075
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0203 0.0469
Loa Loa (eye worm) hypothetical protein 0.0651 0.0919 0.9927
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0017 0.0006 0.0015
Echinococcus multilocularis nmda type glutamate receptor 0.0109 0.0139 0.0321
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0017 0.0006 0.0063
Brugia malayi RNA binding protein 0.0066 0.0076 0.0105
Brugia malayi Steroid receptor seven-up type 2 0.0044 0.0045 0.0062
Schistosoma mansoni tyrosine kinase 0.0014 0.0002 0.0004
Trichomonas vaginalis flap endonuclease-1, putative 0.0083 0.0101 0.238
Brugia malayi Metabotropic glutamate receptor precursor. 0.0014 0.0002 0.0003
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0017 0.0006 0.0093
Schistosoma mansoni SET domain protein 0.0037 0.0035 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0017 0.0217
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0025 0.0085
Schistosoma mansoni glutaminase 0.0302 0.0417 0.0963
Schistosoma mansoni Smad4 0.0016 0.0005 0.0011
Brugia malayi hypothetical protein 0.0455 0.0636 0.0876
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0034 0.0117
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.0122 0.077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0007 0.004
Entamoeba histolytica hypothetical protein 0.0194 0.0261 0.1653
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0012 0.0027
Schistosoma mansoni glutamate receptor NMDA 0.0263 0.0359 0.0831
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0013 0.0049
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0017 0.0006 0.0093
Echinococcus multilocularis mothers against decapentaplegic 6 0.0016 0.0005 0.0011
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.0122 0.1322
Echinococcus granulosus GA binding protein alpha chain 0.0079 0.0095 0.022
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0063
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0014 0.0002 0.0004
Brugia malayi Guanylyl cyclase protein 23 0.0014 0.0002 0.0003
Toxoplasma gondii DNA methyltransferase 2, putative 0.0022 0.0013 0.0028
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0122 0.0443
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0017 0.0006 0.0025
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0023 0.0053
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0014 0.0002 0.002
Schistosoma mansoni kinase 0.005 0.0054 0.0124
Plasmodium vivax exonuclease I, putative 0.0017 0.0006 0.0023
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0045 0.0104
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0076 0.0177
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0017 0.0006 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0122 0.29
Loa Loa (eye worm) glutaminase 0.0302 0.0417 0.4504
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0052 0.0121
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0036 0.0082
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0034 0.0102
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.029 0.0399
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0017 0.0006 0.0022
Schistosoma mansoni lozenge 0.0057 0.0064 0.0148
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0025 0.007
Loa Loa (eye worm) hypothetical protein 0.0214 0.029 0.3131
Brugia malayi Pre-SET motif family protein 0.0245 0.0334 0.046
Treponema pallidum ATP-dependent DNA helicase 0.0031 0.0026 0.0498
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0017 0.0006 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0223
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.002 0.0072
Echinococcus granulosus glutamate receptor subunit protein glur 0.0057 0.0064 0.0147
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0212
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0017 0.0006 0.0015
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0017 0.0006 0.0022
Onchocerca volvulus 0.0024 0.0017 0.0017
Echinococcus granulosus nmda type glutamate receptor 0.0109 0.0139 0.0321
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0044 0.0045 0.0104
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0223
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0008 0.003
Trypanosoma cruzi mitochondrial protein 99, putative 0.0017 0.0006 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0087 0.03
Loa Loa (eye worm) RGC/RGC protein kinase 0.0014 0.0002 0.002
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.0033 0.0075
Leishmania major importin beta-1 subunit, putative 0.005 0.0054 0.0191
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0193 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0013 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Onchocerca volvulus 0.0021 0.0012 0.0012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0044 0.0045 0.0104
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0064 0.023
Schistosoma mansoni DNA polymerase eta 0.0123 0.0158 0.0366
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0076 0.0091 0.0334
Entamoeba histolytica hypothetical protein 0.002 0.0011 0.006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Schistosoma mansoni neutral sphingomyelinase 0.0017 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0044 0.0045 0.0062
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0057 0.0064 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0065 0.0217
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0079 0.0858
Echinococcus granulosus lamin 0.0059 0.0067 0.0155
Trypanosoma brucei DNA repair protein RAD2, putative 0.0017 0.0006 0.0001
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.005 0.0176
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0015 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0124 0.016 0.0582
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0067 0.0092
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0082 0.01 0.0368
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0656 0.0925 1
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0022 0.0013 0.0031
Trypanosoma cruzi DNA polymerase eta, putative 0.0056 0.0063 0.0225
Echinococcus granulosus atrial natriuretic peptide receptor 0.0014 0.0002 0.0004
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0066 0.0717
Loa Loa (eye worm) hypothetical protein 0.0309 0.0426 0.4607
Echinococcus granulosus receptor type guanylyl cyclase 0.0014 0.0002 0.0004
Echinococcus multilocularis receptor type guanylyl cyclase 0.0014 0.0002 0.0004
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0028 0.0038
Echinococcus granulosus endonuclease exonuclease phosphatase 0.021 0.0283 0.0655
Leishmania major hypothetical protein, conserved 0.0017 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0056 0.0062 0.0673
Echinococcus granulosus synaptojanin 1 0.0017 0.0006 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0122 0.29
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0012 0.0027
Loa Loa (eye worm) isocitrate dehydrogenase 0.0036 0.0034 0.0363
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0017 0.0006 0.0025
Schistosoma mansoni topbp1 0.002 0.0011 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0124 0.016 0.0582
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0025 0.007
Onchocerca volvulus 0.0059 0.0067 0.0067
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0017 0.0006 0.0025
Mycobacterium ulcerans hypothetical protein 0.0024 0.0017 0.0217
Brugia malayi ecdysone receptor 0.0021 0.0012 0.0016
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0017 0.0006 0.0014
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0017 0.0023
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0017 0.0006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Echinococcus granulosus ecdysone induced protein 78C 0.0044 0.0045 0.0104
Schistosoma mansoni cpg binding protein 0.0102 0.0128 0.0297
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0012 0.0127
Schistosoma mansoni metabotropic glutamate receptor 0.0014 0.0002 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0087 0.03
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0011 0.002
Schistosoma mansoni ATP-binding cassette transporter 0.0153 0.0203 0.0469
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0066 0.0237
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1774 0.2532 0.5853
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0007 0.004
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0017 0.0006 0.0093
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0122
Brugia malayi Glutamate receptor 1 precursor 0.0153 0.0203 0.0279
Schistosoma mansoni ets-related 0.0238 0.0325 0.0751
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0036 0.0034 0.0078
Brugia malayi polk-prov protein 0.0057 0.0065 0.0089
Onchocerca volvulus 0.0017 0.0006 0.0006
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0052 0.0121
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Loa Loa (eye worm) hypothetical protein 0.0049 0.0052 0.0567
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0012 0.0027
Echinococcus granulosus glutamate receptor 2 0.011 0.0141 0.0326
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0079 0.0184
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0089
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0036 0.0034 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0122 0.0283
Echinococcus multilocularis GA binding protein alpha chain 0.0079 0.0095 0.022
Schistosoma mansoni retinoic acid receptor RXR 0.0044 0.0045 0.0104
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0079 0.0184
Onchocerca volvulus 0.0059 0.0067 0.0067
Schistosoma mansoni topbp1 0.002 0.0011 0.0026
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0014 0.0002 0.0004
Echinococcus multilocularis glutamate receptor 2 0.0167 0.0223 0.0514
Echinococcus granulosus glutamate NMDA receptor subunit 0.0287 0.0394 0.0912
Entamoeba histolytica hypothetical protein 0.005 0.0054 0.0331
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0015 0.0021
Toxoplasma gondii hypothetical protein 0.0054 0.006 0.0198
Schistosoma mansoni cpg binding protein 0.0098 0.0123 0.0285
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0017 0.0321
Echinococcus multilocularis global transcription activator snf2l2 0.0143 0.0188 0.0435
Onchocerca volvulus 0.0455 0.0636 0.0636
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.007 0.0238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0044 0.0045 0.0486
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0018 0.0007 0.002
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0014 0.0002 0.0004
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.0122 0.0168
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0036 0.0082
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0014 0.0002 0.0004
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0017 0.0006 0.0014
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0017 0.0006 0.0022
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.002 0.0072
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0017 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0058 0.0065 0.0708
Leishmania major hypothetical protein, conserved 0.0017 0.0006 0.0015
Echinococcus multilocularis traf and tnf receptor associated protein 0.0017 0.0006 0.0014
Plasmodium vivax SET domain protein, putative 0.0037 0.0036 0.0131
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0076 0.0826
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0037 0.0035 0.0107
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0082 0.01 0.0368
Echinococcus multilocularis Protein lozenge 0.0057 0.0064 0.0148
Brugia malayi RNA, U transporter 1 0.0175 0.0233 0.0321
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Schistosoma mansoni lamin 0.0059 0.0067 0.0155
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0017 0.0056
Echinococcus multilocularis microtubule associated protein 2 0.3022 0.4326 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.006 0.0069 0.0231
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0017 0.0006 0.0063
Echinococcus granulosus BRK domain containing protein 0.0025 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Brugia malayi Pre-SET motif family protein 0.0037 0.0036 0.0049
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0014 0.0002 0.002
Loa Loa (eye worm) flap endonuclease-1 0.0083 0.0101 0.1089
Trypanosoma brucei protein kinase, putative 0.0059 0.0066 0.0223
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0066 0.0153
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.002 0.0065
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0044 0.0045 0.0104
Schistosoma mansoni steroid hormone receptor ad4bp 0.0044 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.0006 0.01
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0066 0.0223
Brugia malayi hypothetical protein 0.0014 0.0002 0.0003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0013 0.0042
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0023 0.0053
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0012 0.0027
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.0122 0.0443
Brugia malayi glutaminase DH11.1 0.0302 0.0417 0.0574
Leishmania major pantothenate kinase subunit, putative 0.0018 0.0007 0.002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0121 0.028
Loa Loa (eye worm) helicase DNA-binding protein 0.0025 0.0018 0.0191
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0203 0.0469
Trypanosoma cruzi mitochondrial protein 99, putative 0.0017 0.0006 0.0015
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0011 0.0015
Mycobacterium ulcerans glutaminase 0.0302 0.0417 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0079 0.0184
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0017 0.0006 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0045 0.0062
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0062 0.0086
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0014
Echinococcus granulosus Chromo domain 0.0025 0.0018 0.0041
Schistosoma mansoni hypothetical protein 0.0194 0.0261 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0052 0.1202
Echinococcus granulosus mothers against decapentaplegic 6 0.0016 0.0005 0.0011
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0017 0.0006 0.0015
Brugia malayi hypothetical protein 0.0021 0.0012 0.0016
Schistosoma mansoni glutamate receptor NMDA 0.0287 0.0394 0.0912
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0013 0.0042
Echinococcus multilocularis muscleblind protein 0.0651 0.0919 0.2123
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0011 0.0026
Echinococcus multilocularis tyrosine kinase 0.0014 0.0002 0.0004
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0057 0.0064 0.0147
Schistosoma mansoni carbon catabolite repressor protein 0.0017 0.0006 0.0014
Echinococcus multilocularis muscleblind protein 1 0.0651 0.0919 0.2123
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0017 0.0097
Plasmodium falciparum flap endonuclease 1 0.0083 0.0101 0.0371
Plasmodium vivax DNA repair protein RAD2, putative 0.0017 0.0006 0.0023
Giardia lamblia hypothetical protein 0.0017 0.0006 0.0001
Echinococcus granulosus peregrin 0.0014 0.0002 0.0004
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0056 0.0063 0.021
Schistosoma mansoni RAR-like nuclear receptor 0.0044 0.0045 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0122 0.29
Echinococcus granulosus metabotropic glutamate receptor 2 0.0014 0.0002 0.0004
Brugia malayi Muscleblind-like protein 0.0651 0.0919 0.1265
Loa Loa (eye worm) glutamate receptor 2 0.0153 0.0203 0.2191
Trichomonas vaginalis ran, putative 0.0022 0.0013 0.0273
Schistosoma mansoni synaptojanin 0.0017 0.0006 0.0014
Plasmodium vivax DEAD/DEAH helicase, putative 0.0022 0.0014 0.0052
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0065 0.0217
Plasmodium falciparum exonuclease I, putative 0.0017 0.0006 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.0192 0.0265
Brugia malayi hypothetical protein 0.002 0.0011 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0122 0.29
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0006 0.0016
Onchocerca volvulus 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.005
Mycobacterium ulcerans DNA polymerase IV 0.0124 0.016 0.3715
Onchocerca volvulus 0.002 0.0011 0.0011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0008 0.0102
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0017 0.0006 0.0025
Brugia malayi hypothetical protein 0.0194 0.0261 0.0359
Brugia malayi nuclear receptor RXR 0.0023 0.0015 0.0021
Echinococcus granulosus tar DNA binding protein 0.0066 0.0076 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0044 0.0045 0.0486
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0017 0.0489
Loa Loa (eye worm) RNA binding protein 0.0066 0.0076 0.0826
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0089
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0103 0.013 0.0472
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0045 0.0062
Giardia lamblia Fructose-bisphosphate aldolase 0.03 0.0413 0.1501
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0037 0.0035 0.008
Echinococcus multilocularis dna polymerase eta 0.0123 0.0158 0.0366
Mycobacterium ulcerans DNA polymerase IV 0.0124 0.016 0.3715
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0052 0.0567
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0011 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0076 0.0177
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0012 0.0127
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0044 0.0045 0.0103
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0082 0.01 0.1081
Echinococcus granulosus neuropeptide receptor A26 0.0475 0.0665 0.1537
Brugia malayi MH1 domain containing protein 0.0035 0.0033 0.0045
Echinococcus granulosus neutral sphingomyelinase 0.0017 0.0006 0.0014
Trichomonas vaginalis lymphoid specific helicase, putative 0.0026 0.002 0.0423
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.021 0.0283 0.0655
Schistosoma mansoni cript-related 0.0017 0.0006 0.0014
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0082 0.01 0.0361
Brugia malayi DKFZp564C0469 protein 0.002 0.0011 0.0015
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.0034
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0122 0.29
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0165
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0045 0.0062
Echinococcus granulosus snurportin 1 0.0656 0.0925 0.2139
Giardia lamblia DNA repair protein RAD52 0.1102 0.1566 0.5752
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0011 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0006 0.0016
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0121 0.0166
Schistosoma mansoni glutamate receptor AMPA 0.0153 0.0203 0.0469
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.013 0.0458
Brugia malayi Glutamate receptor 2 precursor 0.0153 0.0203 0.0279
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0184
Echinococcus multilocularis neuropeptide s receptor 0.0475 0.0665 0.1537
Brugia malayi Ets-domain containing protein 0.0079 0.0095 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0045 0.0062
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0076 0.0826
Schistosoma mansoni hypothetical protein 0.075 0.106 0.2451
Trichomonas vaginalis importin beta-1, putative 0.005 0.0054 0.1247
Echinococcus granulosus global transcription activator snf2l2 0.0143 0.0188 0.0435
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0082 0.01 0.0361
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0014 0.0002 0.0003
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0036 0.0034 0.0117
Plasmodium falciparum telomerase reverse transcriptase 0.1903 0.2718 1
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.0033 0.0075
Trypanosoma brucei unspecified product 0.0066 0.0077 0.0264
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0022 0.0013 0.0031
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0022 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0089
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0007 0.0017
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0036 0.0034 0.0078
Echinococcus granulosus dna polymerase kappa 0.0124 0.016 0.037
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0209 0.0764
Schistosoma mansoni ran 0.0022 0.0013 0.0031
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.0006 0.01
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0165
Echinococcus granulosus disco interacting protein 2 0.0044 0.0045 0.0103
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0082 0.01 0.4108
Entamoeba histolytica recQ family helicase, putative 0.0072 0.0085 0.0534
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.006 0.0069 0.0158
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0017 0.0006 0.0093
Toxoplasma gondii hypothetical protein 0.0094 0.0117 0.0408
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.0033 0.0075
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0012 0.0027
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0044 0.0045 0.0104
Brugia malayi CCR4 0.0017 0.0006 0.0008
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0011 0.0074
Echinococcus granulosus neuropeptide s receptor 0.0475 0.0665 0.1537
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0012 0.0027
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0082 0.01 0.0231
Onchocerca volvulus 0.0043 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0123 0.0158 0.1711
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0017 0.0006 0.0025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0007 0.0017
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0017 0.0006 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0044 0.0045 0.0062
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0072 0.0085 0.0293
Echinococcus granulosus geminin 0.075 0.106 0.2451
Brugia malayi isocitrate dehydrogenase 0.0036 0.0034 0.0046
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0017 0.0006 0.0025
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0082 0.01 1
Echinococcus multilocularis bloom syndrome protein 0.0117 0.015 0.0346
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Schistosoma mansoni flap endonuclease-1 0.0075 0.0089 0.0206
Brugia malayi XPG I-region family protein 0.0017 0.0006 0.0009
Echinococcus multilocularis neutral sphingomyelinase 0.0017 0.0006 0.0014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0167 0.0223 0.0514
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.0122 0.0283
Onchocerca volvulus 0.0049 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0068 0.0079 0.0184
Onchocerca volvulus Protein ultraspiracle homolog 0.0044 0.0045 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0066 0.1551
Loa Loa (eye worm) RecQ helicase 0.0117 0.015 0.162
Loa Loa (eye worm) hypothetical protein 0.0059 0.0067 0.0724
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0167 0.0223 0.0514
Trypanosoma brucei exonuclease, putative 0.0017 0.0006 0.0001
Schistosoma mansoni metabotropic glutamate receptor 0.0014 0.0002 0.0004
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0094 0.0117 0.0429
Trichomonas vaginalis flap endonuclease-1, putative 0.0017 0.0006 0.01
Plasmodium falciparum DNase I-like protein, putative 0.0017 0.0006 0.0022
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0013 0.0144
Plasmodium vivax flap endonuclease 1, putative 0.0083 0.0101 0.0371
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0057 0.0064 0.0147
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0045 0.0062
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0013 0.0031
Echinococcus multilocularis lamin dm0 0.0059 0.0067 0.0155
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0314 0.0433 0.2755
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0017 0.0006 0.0015
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0017 0.0006 0.0093
Leishmania major modification methylase-like protein 0.0022 0.0013 0.0043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0066 0.1551
Loa Loa (eye worm) BRM protein 0.0091 0.0114 0.1227
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0082 0.01 0.0361
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Echinococcus multilocularis mothers against decapentaplegic 2 0.0016 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0232
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0014 0.0002 0.002
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0223
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0029 0.0024 0.009
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0245 0.0334 0.361
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0057 0.0064 0.0147
Echinococcus multilocularis BRK domain containing protein 0.0025 0.0018 0.0041
Plasmodium falciparum importin beta, putative 0.0061 0.007 0.0259
Schistosoma mansoni hypothetical protein 0.0028 0.0023 0.0053
Schistosoma mansoni intermediate filament proteins 0.0059 0.0067 0.0155
Trypanosoma brucei telomerase reverse transcriptase 0.1903 0.2718 1
Trichomonas vaginalis DNA helicase recq, putative 0.0072 0.0085 0.201
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0012 0.0027
Echinococcus multilocularis isocitrate dehydrogenase 0.0036 0.0034 0.0078
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0062 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Echinococcus multilocularis BRK domain containing protein 0.0025 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0651 0.0919 0.9927
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.007 0.0238
Schistosoma mansoni smad1 5 8 and 0.0035 0.0033 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.005 0.0176
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0026 0.002 0.005
Treponema pallidum DNA ligase (lig) 0.002 0.0011 0.0132
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0193 0.4512
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0096 0.012 0.0278
Leishmania major telomerase reverse transcriptase, putative 0.1903 0.2718 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0108
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0203 0.0469
Schistosoma mansoni hypothetical protein 0.0068 0.0079 0.0184
Echinococcus multilocularis BRK domain 0.0025 0.0018 0.0041
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.006 0.0069 0.0094
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0232
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0184
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0066 0.0153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Schistosoma mansoni blooms syndrome DNA helicase 0.0086 0.0106 0.0245
Loa Loa (eye worm) hypothetical protein 0.006 0.0069 0.0741
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.002 0.0051
Schistosoma mansoni cpg binding protein 0.0102 0.0128 0.0297
Brugia malayi Bloom's syndrome protein homolog 0.0117 0.015 0.0206
Echinococcus multilocularis importin subunit beta 1 0.0061 0.007 0.0163
Echinococcus multilocularis glutamate receptor 2 0.011 0.0141 0.0326
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0012 0.0016
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0096 0.012 0.0278
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.1903 0.2718 1
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0062 0.0144
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0036 0.0034 0.0124
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0017 0.0056
Schistosoma mansoni nuclear receptor 0.0021 0.0012 0.0027
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0282
Loa Loa (eye worm) hypothetical protein 0.0061 0.007 0.0761
Loa Loa (eye worm) hypothetical protein 0.0067 0.0079 0.085
Echinococcus multilocularis synaptojanin 1 0.0017 0.0006 0.0014
Giardia lamblia DNA damage repair protein 0.003 0.0025 0.007
Echinococcus multilocularis dna polymerase kappa 0.0124 0.016 0.037
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0017 0.0006 0.0014
Schistosoma mansoni nocturnin 0.0017 0.0006 0.0014
Leishmania major DNA polymerase eta, putative 0.0123 0.0158 0.0576
Entamoeba histolytica hypothetical protein 0.0194 0.0261 0.1653
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0017 0.0217
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0121 0.028
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.012 0.0166
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0017 0.0006 0.0063
Trichomonas vaginalis ap endonuclease, putative 0.0082 0.01 0.2363
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.0033 0.0351
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0066 0.1551
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0022 0.0014 0.003
Treponema pallidum exodeoxyribonuclease (exoA) 0.0082 0.01 0.2312
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0007 0.004
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0013 0.0028
Schistosoma mansoni tyrosine kinase 0.0014 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0146 0.0192 0.2079
Echinococcus multilocularis glutamate receptor 2 0.0153 0.0203 0.0469
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0005 0.005
Trypanosoma cruzi importin beta-1 subunit, putative 0.005 0.0054 0.0191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0121 0.028
Brugia malayi hypothetical protein 0.0023 0.0015 0.0021
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1102 0.1566 1
Brugia malayi MH2 domain containing protein 0.0515 0.0722 0.0995
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0044 0.0045 0.0104
Schistosoma mansoni Smad4 0.0016 0.0005 0.0011
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0008 0.003
Echinococcus granulosus exonuclease 1 0.0017 0.0006 0.0014
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0025 0.007
Brugia malayi ecdysteroid receptor 0.0044 0.0045 0.0062
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0167 0.0223 0.0514
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0044 0.0045 0.0104
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0044 0.0045 0.0104
Schistosoma mansoni exonuclease 0.0017 0.0006 0.0014
Schistosoma mansoni smad 0.0035 0.0033 0.0075
Echinococcus granulosus replication factor c subunit 1 0.002 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0122
Loa Loa (eye worm) glutamate receptor 1 0.0153 0.0203 0.2191
Loa Loa (eye worm) hypothetical protein 0.0057 0.0065 0.0698
Echinococcus multilocularis deoxyribonuclease 1 2 0.0017 0.0006 0.0014
Schistosoma mansoni gabp alpha 0.0079 0.0095 0.022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0067
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0034 0.0078
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0034 0.0102
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0121 0.028
Trichomonas vaginalis ap endonuclease, putative 0.0082 0.01 0.2363
Brugia malayi intermediate filament protein 0.0059 0.0067 0.0092
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0079 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Echinococcus multilocularis thyroid hormone receptor alpha 0.0044 0.0045 0.0104
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0066 0.0237
Echinococcus multilocularis neuropeptide receptor A26 0.0475 0.0665 0.1537
Echinococcus granulosus cpg binding protein 0.0102 0.0128 0.0297
Schistosoma mansoni ap endonuclease 0.0082 0.01 0.0231
Leishmania major hypothetical protein, conserved 0.0017 0.0006 0.0015
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0223
Echinococcus granulosus glutamate receptor 2 0.0167 0.0223 0.0514
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.002 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0165
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0334 0.0462 0.1683
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.0249 0.0249
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0287 0.0394 0.0912
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0012 0.0016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.003 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0165
Schistosoma mansoni hypothetical protein 0.075 0.106 0.2451
Leishmania major GTP-binding protein, putative 0.0022 0.0013 0.0042
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0011 0.0026
Echinococcus granulosus mothers against decapentaplegic 2 0.0016 0.0005 0.0011
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0025 0.0085
Echinococcus multilocularis nmda type glutamate receptor 0.0152 0.0201 0.0464
Echinococcus multilocularis disco interacting protein 2 0.0044 0.0045 0.0103
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0017 0.0217
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0017 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0089
Echinococcus granulosus muscleblind protein 0.0651 0.0919 0.2123
Echinococcus granulosus ATP dependent DNA helicase Q5 0.006 0.0069 0.0158
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0045 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0223
Giardia lamblia Exonuclease 1 0.0017 0.0006 0.0001
Echinococcus multilocularis nibrin 0.002 0.0011 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0121 0.028
Entamoeba histolytica exonuclease, putative 0.0017 0.0006 0.0027
Brugia malayi Telomerase reverse transcriptase 0.5065 0.7264 1
Entamoeba histolytica DNA-repair protein, putative 0.0017 0.0006 0.0027
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0025 0.0092
Loa Loa (eye worm) glutamate receptor 0.0014 0.0002 0.002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0121 0.1307
Schistosoma mansoni synaptojanin 0.0017 0.0006 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.3022 0.4326 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.006 0.0069 0.0231
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0025 0.007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0079 0.0109
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0044 0.0045 0.0104
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0083 0.0101 0.0364
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0017 0.0056
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0034 0.0078
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0013 0.0028
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0017 0.0006 0.0015
Trichomonas vaginalis DNA helicase recq1, putative 0.0117 0.015 0.3566
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.0006 0.0001
Brugia malayi hypothetical protein 0.0023 0.0015 0.0021
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0052 0.0121
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0044 0.0045 0.0486
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0057 0.0064 0.0147
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0184
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Echinococcus granulosus flap endonuclease 1 0.0083 0.0101 0.0233
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0017 0.0006 0.0015
Echinococcus granulosus ATP dependent DNA helicase Q1 0.006 0.0069 0.0158
Brugia malayi exodeoxyribonuclease III family protein 0.0082 0.01 0.0138
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0012 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0122
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0011 0.0041
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0066 0.0223
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0017 0.0006 0.0093
Schistosoma mansoni hypothetical protein 0.0656 0.0925 0.2139
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.007 0.0238
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0121 0.028
Entamoeba histolytica Flap nuclease, putative 0.0083 0.0101 0.0632
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0082 0.01 0.2247
Echinococcus granulosus nmda type glutamate receptor 0.0152 0.0201 0.0464
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0017 0.0006 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0044 0.0045 0.0062
Plasmodium vivax telomerase reverse transcriptase, putative 0.1903 0.2718 1
Schistosoma mansoni transcription factor LCR-F1 0.0194 0.0261 0.0602
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.0209 0.075
Echinococcus multilocularis smad 0.0035 0.0033 0.0075
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0017 0.0006 0.0022
Schistosoma mansoni nuclear receptor 0.0021 0.0012 0.0027
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.002 0.0051
Loa Loa (eye worm) hypothetical protein 0.0455 0.0636 0.6874
Schistosoma mansoni DNA helicase recq5 0.006 0.0069 0.0158
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0014 0.0002 0.0004
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0066 0.0153
Leishmania major endonuclease/exonuclease protein-like protein 0.0017 0.0006 0.0015
Trichomonas vaginalis exonuclease%2C+putative 0.0017 0.0006 0.01
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0062 0.0144
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0036 0.0034 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0066 0.0153
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0026 0.0089
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0413 0.9909
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0165
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0122
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.0033 0.0351
Schistosoma mansoni hypothetical protein 0.0057 0.0064 0.0147
Brugia malayi conserved hypotetical protein 0.0021 0.0012 0.0016
Echinococcus multilocularis lamin 0.0059 0.0067 0.0155
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0037 0.0035 0.008
Trypanosoma brucei DNA polymerase IV, putative 0.0124 0.016 0.0568
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0036 0.0082
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0103 0.013 0.5425
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0012 0.0027
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0067 0.0724
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0062 0.0144
Brugia malayi CXXC zinc finger family protein 0.0098 0.0123 0.017
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0082 0.01 0.0627
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0052 0.1202
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0076 0.0177
Trypanosoma cruzi DNA polymerase kappa, putative 0.0124 0.016 0.0582
Trichomonas vaginalis DNA helicase recq, putative 0.0117 0.015 0.3566
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0017 0.0006 0.0015
Brugia malayi MH2 domain containing protein 0.0016 0.0005 0.0006
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0036 0.0034 0.1212
Trypanosoma cruzi DNA polymerase eta, putative 0.0123 0.0158 0.0576
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0012 0.0027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0132 0.0172 0.0398
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0013 0.0028
Schistosoma mansoni hypothetical protein 0.0146 0.0192 0.0445
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0096 0.012 0.0278
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0044 0.0045 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0045 0.0062
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0012 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0044 0.0045 0.0104
Trypanosoma brucei unspecified product 0.0066 0.0077 0.0264
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0007 0.0017
Loa Loa (eye worm) RGC/RGC protein kinase 0.0014 0.0002 0.002
Onchocerca volvulus 0.0021 0.0012 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.0462 0.1695
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0017 0.0023
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0079 0.0095 0.1027
Leishmania major DNA polymerase eta, putative 0.0056 0.0063 0.0225
Schistosoma mansoni hypothetical protein 0.0068 0.0079 0.0184
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0016 0.0005 0.0005
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0017 0.0006 0.0025
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0082 0.01 0.0347
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0045 0.0104
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0017 0.0006 0.0015
Echinococcus multilocularis BRK domain containing protein 0.0025 0.0018 0.0041
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0022 0.0013 0.005
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Echinococcus multilocularis flap endonuclease GEN 1 0.0017 0.0006 0.0014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0167 0.0223 0.0514
Loa Loa (eye worm) XPG I-region family protein 0.0017 0.0006 0.0067
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0017 0.0006 0.0015
Schistosoma mansoni DNA ligase IV 0.002 0.0011 0.0026
Brugia malayi MH2 domain containing protein 0.0035 0.0033 0.0045
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0011 0.002
Brugia malayi nuclear receptor NHR-88 0.0021 0.0012 0.0016
Brugia malayi topoisomerase 0.002 0.0011 0.0015
Giardia lamblia Kinase, PLK 0.0098 0.0122 0.0429
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0017 0.0217
Brugia malayi nuclear hormone receptor 0.0021 0.0012 0.0016
Loa Loa (eye worm) MBCTL1 0.0056 0.0062 0.0673
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0014 0.0002 0.0002
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0017 0.0006 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0066 0.1551
Echinococcus multilocularis flap endonuclease 1 0.0083 0.0101 0.0233
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0044 0.0045 0.0062
Toxoplasma gondii exonuclease III APE 0.0082 0.01 0.0347
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0015 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0076 0.0177
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0082 0.01 0.0347
Brugia malayi tailless protein 0.0021 0.0012 0.0016
Echinococcus granulosus traf and tnf receptor associated protein 0.0017 0.0006 0.0014
Echinococcus granulosus DNA methyltransferase 2, putative 0.0022 0.0013 0.0031
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0044 0.0045 0.0104
Onchocerca volvulus 0.0044 0.0045 0.0045
Leishmania major DNA damage repair protein, putative 0.003 0.0025 0.0085
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.005 0.0176
Loa Loa (eye worm) MH2 domain-containing protein 0.0515 0.0722 0.7807
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Brugia malayi hypothetical protein 0.002 0.0011 0.0015
Leishmania major hypothetical protein, conserved 0.0026 0.002 0.0065
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.006 0.0069 0.0252
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0052 0.0121
Plasmodium vivax exodeoxyribonuclease III, putative 0.0017 0.0006 0.0022
Giardia lamblia Replication factor C, subunit 1 0.002 0.0011 0.002
Trichomonas vaginalis DNA polymerase eta, putative 0.0124 0.016 0.3809
Echinococcus multilocularis Chromo domain 0.0025 0.0018 0.0041
Schistosoma mansoni smad1 5 8 and 0.0035 0.0033 0.0075
Giardia lamblia Sgs1 DNA helicase, putative 0.006 0.0069 0.0231
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0017 0.0006 0.0014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0036 0.0082
Mycobacterium ulcerans hypothetical protein 0.003 0.0025 0.041
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0066 0.0237
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0054 0.1247
Trichomonas vaginalis Phospholipase C precursor, putative 0.0017 0.0006 0.0093
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0025 0.0085
Trypanosoma brucei DNA polymerase eta, putative 0.0123 0.0158 0.0562
Brugia malayi Smad1 0.0035 0.0033 0.0045
Echinococcus multilocularis cpg binding protein 0.0102 0.0128 0.0297
Echinococcus multilocularis BRK domain containing protein 0.0025 0.0018 0.0041
Entamoeba histolytica recQ family DNA helicase 0.0031 0.0026 0.0155
Echinococcus granulosus nibrin 0.002 0.0011 0.0026
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0122 0.0443
Brugia malayi Receptor family ligand binding region containing protein 0.0014 0.0002 0.0003
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0025 0.007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0017 0.0217
Echinococcus multilocularis dnaJ subfamily B 0.0872 0.1236 0.2858
Toxoplasma gondii isocitrate dehydrogenase 0.0036 0.0034 0.0102
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0076 0.0177
Onchocerca volvulus 0.0014 0.0002 0.0002
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0022 0.0013 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0012 0.0027
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0013 0.0018
Trypanosoma brucei DNA polymerase IV, putative 0.0117 0.015 0.0532
Echinococcus granulosus glutamate receptor NMDA 0.0095 0.0119 0.0275
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0066 0.0237
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0015 0.0165
Brugia malayi hypothetical protein 0.0017 0.0006 0.0009
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0022 0.0013 0.0074
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0017 0.0006 0.0022
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0036 0.0034 0.0078
Schistosoma mansoni ap endonuclease 0.0082 0.01 0.0231
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0026 0.0089
Entamoeba histolytica exonuclease, putative 0.0017 0.0006 0.0027
Schistosoma mansoni importin beta-1 0.0061 0.007 0.0163
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0013 0.003
Onchocerca volvulus 0.0037 0.0036 0.0036
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0044 0.0045 0.0104
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0083 0.0101 0.035
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0011 0.0034
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.006 0.0069 0.0094
Schistosoma mansoni blooms syndrome DNA helicase 0.0031 0.0026 0.006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0063
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0057 0.0064 0.0147
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0028 0.0298
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0066 0.0237
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.0033 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.0087 0.03
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0026 0.0075
Echinococcus granulosus lamin dm0 0.0059 0.0067 0.0155
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0076 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0025 0.0085
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0017 0.0006 0.0015
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0022 0.0013 0.005
Loa Loa (eye worm) steroid hormone receptor 0.0044 0.0045 0.0486
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0045 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0045 0.0062
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0076 0.0105
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0012 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0044 0.0045 0.0486
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0017 0.0006 0.0015
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0052 0.0121
Schistosoma mansoni coup transcription factor 0.0044 0.0045 0.0104
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.006 0.0069 0.0158
Brugia malayi steroid hormone receptor 0.0044 0.0045 0.0062
Echinococcus multilocularis chromodomain helicase DNA binding protein 7 0.0025 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Loa Loa (eye worm) hypothetical protein 0.0185 0.0249 0.2687
Echinococcus granulosus intermediate filament protein 0.0059 0.0067 0.0155
Schistosoma mansoni phd finger protein 0.0014 0.0002 0.0004
Schistosoma mansoni smad1 5 8 and 0.0035 0.0033 0.0075
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0124 0.016 0.3809
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0017 0.0217
Schistosoma mansoni glutamate receptor kainate 0.0153 0.0203 0.0469
Loa Loa (eye worm) hypothetical protein 0.0044 0.0045 0.0486
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0036 0.0082
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0044 0.0045 0.0104
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.0462 0.1695
Brugia malayi Ets-domain containing protein 0.0079 0.0095 0.0131
Entamoeba histolytica hypothetical protein 0.0194 0.0261 0.1653
Echinococcus granulosus importin subunit beta 1 0.0061 0.007 0.0163
Echinococcus granulosus FTZ F1 alpha 0.0044 0.0045 0.0104
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0012 0.0012
Leishmania major DNA polymerase kappa, putative 0.0103 0.013 0.0472
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0012 0.0012
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0025 0.0092
Leishmania major DNA polymerase kappa, putative 0.003 0.0025 0.0085
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0012 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.0123 0.0158 0.0218
Brugia malayi MAP kinase sur-1 0.0059 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0127
Brugia malayi mothers against decapentaplegic homolog 3 0.0016 0.0005 0.0006
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0167 0.0223 0.0514
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0015 0.0021
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0044 0.0045 0.0104
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0013 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0006 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0044 0.0045 0.0486
Brugia malayi nuclear receptor NHR-88 0.0044 0.0045 0.0062
Schistosoma mansoni hypothetical protein 0.0068 0.0079 0.0184
Trypanosoma brucei DNA polymerase kappa, putative 0.0124 0.016 0.0568
Trypanosoma brucei polo-like protein kinase 0.0098 0.0122 0.0429
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0074 0.0089 0.0306
Entamoeba histolytica deoxycytidyl transferase, putative 0.0096 0.012 0.0757
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.002 0.0065
Brugia malayi hypothetical protein 0.0026 0.002 0.0027
Brugia malayi Isocitrate dehydrogenase 0.0036 0.0034 0.0046
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0017 0.0006 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0223
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0017 0.0217
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0066 0.0237
Echinococcus granulosus tyrosine kinase 0.0014 0.0002 0.0004
Schistosoma mansoni hypothetical protein 0.0025 0.0018 0.0041
Brugia malayi photoreceptor-specific nuclear receptor 0.0044 0.0045 0.0062
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0079 0.0858
Loa Loa (eye worm) Smad1 0.0035 0.0033 0.0351
Echinococcus multilocularis snurportin 1 0.0656 0.0925 0.2139
Leishmania major mitochondrial DNA polymerase beta 0.0334 0.0462 0.1695
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0194 0.0261 0.0602
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.002
Schistosoma mansoni smad 0.0016 0.0005 0.0011
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0017 0.0097
Chlamydia trachomatis DNA ligase 0.002 0.0011 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0223
Echinococcus granulosus metabotropic glutamate receptor 5 0.0014 0.0002 0.0004
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0057 0.0064 0.0147
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0167 0.0223 0.0514
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0007 0.0017
Echinococcus granulosus microtubule associated protein 2 0.3022 0.4326 1
Loa Loa (eye worm) nuclear factor I 0.0019 0.001 0.0108
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.005 0.0161
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0223
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0012 0.0027
Brugia malayi hypothetical protein 0.0021 0.0012 0.0016
Brugia malayi mbt repeat family protein 0.0049 0.0052 0.0072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0089

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) Tested in vitro for the affinity against NMDA receptor in a cortical wedge assay; A- compound acts as antagonist ChEMBL. No reference
IC50 (binding) = 1055 nM Tested in vitro for the affinity against NMDA receptor by examining its ability to inhibit [3H]-CGS-19,755 binding ChEMBL. No reference
MED (functional) > 160 mg kg-1 Minimum effective dose tested by ip administration for its ability to block NMDA induced lethality in mice. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.