Detailed information for compound 1078095

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 215.312 | Formula: C10H17NO2S
  • H donors: 1 H acceptors: 2 LogP: 2.08 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCC(=O)N[C@H]1CCSC1=O
  • InChi: 1S/C10H17NO2S/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)/t8-/m0/s1
  • InChiKey: SVRCTEGNIYMXSN-QMMMGPOBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Aliivibrio fischeri Transcriptional activator protein luxR Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ephrin type A receptor 4 A 0.0229 0.2082 0.2082
Onchocerca volvulus Huntingtin homolog 0.0136 0.1205 0.2322
Echinococcus granulosus importin subunit beta 1 0.01 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.0021 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0153 0.1368 0.1368
Loa Loa (eye worm) beta-lactamase 0.0042 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0115 0.1008 0.1008
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0124 0.0124
Onchocerca volvulus 0.0009 0.0008 0.0016
Schistosoma mansoni DNA polymerase eta 0.0017 0.0085 0.0085
Mycobacterium tuberculosis Conserved protein 0.0042 0.0316 0.0433
Echinococcus multilocularis Kelch repeat type 1 0.0105 0.0914 0.0914
Trichomonas vaginalis hypothetical protein 0.0019 0.0098 0.0146
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0022 0.0124 0.0124
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0009 0.0006 0.0006
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0154 0.1379 0.2256
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Echinococcus multilocularis peregrin 0.0075 0.0633 0.0633
Trypanosoma brucei metacaspase MCA3 0.0153 0.1368 0.6718
Trichomonas vaginalis importin beta-1, putative 0.0081 0.0685 0.1282
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0023 0.0112
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0027 0.0178 0.0178
Trypanosoma cruzi metacaspase, putative 0.0153 0.1368 0.6718
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.0079 0.067 0.1041
Loa Loa (eye worm) importin-beta domain-containing protein 0.0019 0.0098 0.0098
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0113 0.099 0.1589
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0019 0.0098 0.0482
Entamoeba histolytica hypothetical protein 0.0026 0.017 0.0729
Brugia malayi Liprin-alpha 2 0.0027 0.0178 0.0361
Echinococcus granulosus SAM and MBT domain containing protein 0.0055 0.0444 0.0444
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Mycobacterium ulcerans aldehyde dehydrogenase 0.0113 0.099 0.1646
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0067 0.0557 0.0847
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0009 0.0006 0.0006
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0073 0.0614 0.4398
Echinococcus granulosus oncosphere protein Tso22e 0.0154 0.1377 0.1377
Brugia malayi Bromodomain containing protein 0.0266 0.2439 0.4932
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0006 0.0012
Echinococcus granulosus methyl CpG binding domain protein 2 0.0061 0.0492 0.0492
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0177 0.1595 0.7832
Echinococcus multilocularis jumonji domain containing 1A 0.0022 0.0124 0.0124
Echinococcus granulosus dna polymerase eta 0.0017 0.0085 0.0085
Plasmodium falciparum protein kinase, putative 0.003 0.0202 0.1331
Plasmodium vivax acyl-CoA synthetase, putative 0.0016 0.0071 0.0358
Brugia malayi Troponin T 0.0074 0.0616 0.1247
Plasmodium vivax SET domain protein, putative 0.007 0.0584 0.4169
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.1368 0.2603
Echinococcus granulosus SAM domain containing protein 0.0027 0.0178 0.0178
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Echinococcus multilocularis phd:f box containing protein 0.0022 0.0124 0.0124
Schistosoma mansoni troponin I 0.0124 0.1094 0.1094
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0009 0.0006 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0009 0.0006 0.0006
Echinococcus granulosus FTZ F1 alpha 0.0009 0.0006 0.0006
Toxoplasma gondii HEAT repeat-containing protein 0.0019 0.0098 0.0479
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0316 0.155
Onchocerca volvulus 0.0027 0.0178 0.0343
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0178
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0081 0.0685 0.1282
Brugia malayi coiled-coil like protein 1 0.0027 0.0178 0.0361
Brugia malayi Tnks protein 0.0027 0.0178 0.0361
Trichomonas vaginalis CAMK family protein kinase 0.0224 0.2037 0.3897
Trypanosoma cruzi metacaspase, putative 0.0153 0.1368 0.6718
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.008 0.0677 0.0677
Brugia malayi kap beta 3 protein 0.0019 0.0098 0.0198
Trypanosoma brucei unspecified product 0.0012 0.0033 0.0164
Schistosoma mansoni hypothetical protein 0.0105 0.0914 0.0914
Echinococcus multilocularis lysine specific demethylase 5A 0.0081 0.0687 0.0687
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0063 0.0517 0.1045
Echinococcus granulosus fetal alzheimer antigen falz 0.008 0.0677 0.0677
Echinococcus granulosus mitogen activated protein kinase 0.0177 0.1595 0.1595
Onchocerca volvulus Protein ultraspiracle homolog 0.0009 0.0006 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0423 0.0855
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0301
Schistosoma mansoni caspase-7 (C14 family) 0.0405 0.375 0.375
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0131 0.1157 0.1157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0271 0.0271
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0117 0.1029 0.1029
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0271 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0301
Toxoplasma gondii aldehyde dehydrogenase 0.0113 0.099 0.6152
Echinococcus granulosus troponin i 0.0124 0.1094 0.1094
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0177 0.1595 0.7832
Echinococcus multilocularis JmjC domain containing protein 4 0.0022 0.0124 0.0124
Schistosoma mansoni SET domain protein 0.0009 0.0008 0.0008
Echinococcus multilocularis FTZ F1 alpha 0.0009 0.0006 0.0006
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0085 0.0415
Mycobacterium ulcerans beta-lactamase 0.0042 0.0316 0.0498
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0023 0.0112
Loa Loa (eye worm) hypothetical protein 0.0042 0.0316 0.0316
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0085 0.0171
Brugia malayi Troponin I 0.0124 0.1094 0.2213
Onchocerca volvulus Troponin I homolog 0.0124 0.1094 0.2108
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0021 0.0122 0.0169
Toxoplasma gondii PHD-finger domain-containing protein 0.0067 0.0554 0.3376
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0071
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0405 0.375 0.375
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0027 0.0178 0.0361
Brugia malayi hypothetical protein 0.003 0.0203 0.0411
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0051 0.0398 0.1952
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0423 0.0423
Brugia malayi beta-lactamase 0.0042 0.0316 0.0638
Trypanosoma brucei polo-like protein kinase 0.0224 0.2037 1
Schistosoma mansoni hypothetical protein 0.0027 0.0178 0.0178
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0073 0.0614 0.3763
Leishmania major DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Brugia malayi hypothetical protein 0.0011 0.0023 0.0046
Trypanosoma brucei unspecified product 0.0012 0.0033 0.0164
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0113 0.099 0.4862
Schistosoma mansoni kinase 0.0115 0.1003 0.1003
Echinococcus multilocularis lysine specific demethylase 6a 0.0022 0.0124 0.0124
Echinococcus granulosus mitogen activated protein kinase 3 0.0177 0.1595 0.1595
Schistosoma mansoni jumonji/arid domain-containing protein 0.0088 0.0751 0.0751
Schistosoma mansoni hypothetical protein 0.0022 0.0127 0.0127
Schistosoma mansoni retinoic acid receptor RXR 0.0009 0.0006 0.0006
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0316 0.0433
Onchocerca volvulus 0.0557 0.519 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0047 0.0047
Echinococcus multilocularis SAM and MBT domain containing protein 0.0055 0.0444 0.0444
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0022 0.0124 0.061
Plasmodium vivax hypothetical protein, conserved 0.0067 0.0554 0.3945
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0128 0.1126 0.1126
Schistosoma mansoni ran 0.0073 0.0614 0.0614
Brugia malayi Immunoglobulin I-set domain containing protein 0.0011 0.0022 0.0044
Leishmania major DNA polymerase eta, putative 0.0017 0.0085 0.0415
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0017 0.0085 0.0119
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0022 0.0124 0.061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0423 0.0423
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0009 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0115 0.1007 0.1007
Trichomonas vaginalis CAMK family protein kinase 0.0224 0.2037 0.3897
Trypanosoma cruzi polo-like protein kinase, putative 0.0224 0.2037 1
Onchocerca volvulus 0.0011 0.0022 0.0042
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0.0023 0.0046
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0017 0.0085 0.0415
Loa Loa (eye worm) hypothetical protein 0.0158 0.1414 0.1414
Plasmodium vivax SET domain containing protein 0.0011 0.0023 0.0005
Echinococcus multilocularis stromal interaction molecule 1 0.0027 0.0178 0.0178
Brugia malayi PHD-finger family protein 0.0067 0.0554 0.112
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0085 0.0306
Trypanosoma cruzi metacaspase, putative 0.0153 0.1368 0.6718
Entamoeba histolytica hypothetical protein 0.004 0.0297 0.1362
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0151 0.0151
Trypanosoma brucei Metacaspase-4 0.0153 0.1368 0.6718
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0023 0.0023
Treponema pallidum DNA ligase (lig) 0.0011 0.0023 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0033 0.0164
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0021 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0136 0.1205 0.1205
Loa Loa (eye worm) hypothetical protein 0.0011 0.0023 0.0023
Trichomonas vaginalis CAMK family protein kinase 0.0224 0.2037 0.3897
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0127 0.0661
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0027 0.0178 0.0178
Echinococcus granulosus liprin beta 1 0.0027 0.0178 0.0178
Schistosoma mansoni hypothetical protein 0.0027 0.0178 0.0178
Echinococcus granulosus jumonji domain containing 1A 0.0022 0.0124 0.0124
Trypanosoma brucei protein kinase, putative 0.0177 0.1595 0.7832
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0297 0.0297
Brugia malayi jmjC domain containing protein 0.0022 0.0124 0.0251
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0316 0.155
Echinococcus granulosus transportin 1 0.0019 0.0098 0.0098
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0177 0.1595 0.7832
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0444 0.0444
Plasmodium falciparum importin beta, putative 0.01 0.0864 0.6251
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0067 0.0557 0.0557
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0006 0.0006
Brugia malayi PHD-finger family protein 0.0088 0.0756 0.153
Giardia lamblia PHD finger protein 15 0.0067 0.0554 0.2636
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0074 0.062 0.1017
Onchocerca volvulus 0.0226 0.2058 0.3965
Onchocerca volvulus Cell death protein 3 homolog 0.0296 0.2717 0.5235
Trichomonas vaginalis ran, putative 0.0073 0.0614 0.1145
Trichomonas vaginalis CAMK family protein kinase 0.0224 0.2037 0.3897
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0073 0.0614 0.4398
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0009 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Brugia malayi Cell death protein 3 precursor 0.0296 0.2717 0.5496
Brugia malayi ephrin receptor 1 precursor 0.0109 0.0951 0.1923
Echinococcus granulosus microtubule associated protein 2 0.0827 0.7742 0.7742
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.017 0.0284
Schistosoma mansoni importin-beta 2 0.0019 0.0098 0.0098
Echinococcus granulosus ecdysone induced protein 78C 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0151 0.1352 0.1352
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0009 0.0006 0.0012
Brugia malayi hypothetical protein 0.0531 0.4944 1
Entamoeba histolytica hypothetical protein 0.004 0.0297 0.1362
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0063 0.0517 0.0517
Giardia lamblia Kinase, PLK 0.0224 0.2037 1
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0975 0.1843
Echinococcus multilocularis mitogen activated protein kinase 0.0177 0.1595 0.1595
Loa Loa (eye worm) hypothetical protein 0.0011 0.0023 0.0023
Echinococcus granulosus Sterile alpha motif SAM 0.0027 0.0178 0.0178
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0316 0.0433
Echinococcus multilocularis thyroid hormone receptor alpha 0.0009 0.0006 0.0006
Echinococcus multilocularis liprin alpha 2 0.0027 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0063 0.0517 0.0517
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0203 0.1147
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0316 0.0638
Brugia malayi hypothetical protein 0.0027 0.0178 0.0361
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0316 0.0316
Brugia malayi jmjC domain containing protein 0.0022 0.0124 0.0251
Echinococcus multilocularis GPCR, family 2 0.0037 0.0271 0.0271
Echinococcus multilocularis translational activator gcn1 0.0019 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0011 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0531 0.4944 0.4944
Loa Loa (eye worm) bromodomain containing protein 0.0063 0.0513 0.0513
Trypanosoma cruzi metacaspase 5, putative 0.0153 0.1368 0.6718
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0055 0.0444 0.0856
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0009 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0122 0.0169
Schistosoma mansoni importin beta-1 0.01 0.0864 0.0864
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0316 0.0566
Echinococcus multilocularis zinc finger protein 0.007 0.0577 0.0577
Loa Loa (eye worm) CAMK protein kinase 0.0011 0.0022 0.0022
Brugia malayi mbt repeat family protein 0.0055 0.0444 0.0898
Entamoeba histolytica hypothetical protein 0.004 0.0297 0.1362
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Echinococcus granulosus phd:f box containing protein 0.0022 0.0124 0.0124
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0203 0.0997
Brugia malayi nuclear hormone receptor 0.0009 0.0006 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.0017 0.0085 0.0415
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0073 0.0614 0.3017
Brugia malayi hypothetical protein 0.0143 0.1269 0.2566
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0009 0.0006 0.0006
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.0079 0.067 0.1102
Loa Loa (eye worm) hypothetical protein 0.0015 0.0063 0.0063
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0478 0.4441 0.8983
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0122 0.06
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0122 0.06
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0154 0.1377 0.2652
Entamoeba histolytica HEAT repeat domain containing protein 0.0019 0.0098 0.0374
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0108 0.0936 0.4536
Brugia malayi PHD-finger family protein 0.0029 0.0191 0.0386
Schistosoma mansoni tsg101-related 0.0108 0.0936 0.0936
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Loa Loa (eye worm) kap beta 3 protein 0.0019 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0143 0.1269 0.1269
Onchocerca volvulus Bile acid receptor homolog 0.0009 0.0006 0.0011
Schistosoma mansoni troponin I 0.0124 0.1094 0.1094
Mycobacterium leprae PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN 0.0079 0.067 0.1102
Brugia malayi mbt repeat family protein 0.0055 0.0444 0.0898
Echinococcus granulosus dna polymerase kappa 0.0017 0.0085 0.0085
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0067 0.0557 0.2734
Mycobacterium ulcerans lipase LipD 0.0042 0.0316 0.0498
Echinococcus multilocularis polycomb protein SCMH1 0.0055 0.0444 0.0444
Loa Loa (eye worm) TK/EPH protein kinase 0.0291 0.2668 0.2668
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0006 0.0012
Brugia malayi SET domain containing protein 0.0009 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0023 0.0023
Plasmodium vivax transportin, putative 0.0019 0.0098 0.0559
Loa Loa (eye worm) hypothetical protein 0.0067 0.0554 0.0554
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0127 0.0622
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0085 0.0037
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0011 0.0022 0.0022
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0177 0.1595 0.7832
Mycobacterium tuberculosis Possible two component transcriptional regulatory protein (probably LuxR-family) 0.0079 0.067 0.1041
Onchocerca volvulus 0.0143 0.1269 0.2444
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0006 0.0006
Brugia malayi Neurabin protein 1 0.0027 0.0178 0.0361
Brugia malayi protein unc-22 0.0011 0.0022 0.0044
Loa Loa (eye worm) troponin 0.0074 0.0616 0.0616
Schistosoma mansoni hypothetical protein 0.008 0.0678 0.0678
Schistosoma mansoni hypothetical protein 0.0399 0.369 0.369
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0009 0.0006 0.0006
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0006 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0203 0.134
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0224 0.2037 0.2037
Trypanosoma cruzi metacaspase 5, putative 0.0153 0.1368 0.6718
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0215 0.0436
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0122 0.0169
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0203 0.134
Echinococcus granulosus PHD finger protein rhinoceros 0.0067 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0251 0.2295 0.2295
Plasmodium falciparum metacaspase 1 0.0153 0.1368 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0124 0.0124
Echinococcus multilocularis apoptotic protease activating factor 1 0.0143 0.1269 0.1269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0009 0.0006 0.0006
Trypanosoma brucei beta lactamase 0.0074 0.062 0.3045
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0224 0.2037 0.2037
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0203 0.134
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0316 0.0433
Trypanosoma brucei importin beta-1 subunit, putative 0.01 0.0864 0.4242
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0224 0.2037 0.2037
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Schistosoma mansoni zinc finger protein 0.0054 0.0433 0.0433
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0085 0.0171
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0074 0.0616 0.1187
Echinococcus granulosus peregrin 0.0075 0.0633 0.0633
Brugia malayi topoisomerase 0.0011 0.0023 0.0046
Echinococcus multilocularis caspase 8 0.0153 0.1368 0.1368
Echinococcus granulosus importin 5 0.0019 0.0098 0.0098
Echinococcus granulosus GPCR family 2 0.0037 0.0271 0.0271
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0212 0.1925 0.1925
Onchocerca volvulus 0.0014 0.0055 0.0105
Echinococcus granulosus nibrin 0.0011 0.0023 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0009 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Brugia malayi hypothetical protein 0.0074 0.0616 0.1247
Schistosoma mansoni tankyrase 0.0027 0.0178 0.0178
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.2037 0.2037
Echinococcus multilocularis caspase 2 0.0296 0.2717 0.2717
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0316 0.0316
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0153 0.1368 0.8557
Brugia malayi nuclear receptor NHR-88 0.0009 0.0006 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.1368 0.2603
Mycobacterium ulcerans hypothetical protein 0.0021 0.0122 0.0169
Echinococcus granulosus caspase 2 0.0296 0.2717 0.2717
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0158 0.1414 0.1414
Plasmodium vivax metacaspase 1, putative 0.0153 0.1368 1
Echinococcus multilocularis jumonji domain containing protein 0.0093 0.0802 0.0802
Loa Loa (eye worm) hypothetical protein 0.0011 0.0023 0.0023
Mycobacterium tuberculosis Conserved protein 0.0042 0.0316 0.0433
Mycobacterium ulcerans hypothetical protein 0.0042 0.0316 0.0498
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.007 0.0584 0.0584
Schistosoma mansoni hypothetical protein 0.0027 0.0178 0.0178
Giardia lamblia Kinase, CMGC MAPK 0.0177 0.1595 0.7807
Leishmania major GTP-binding protein, putative 0.0073 0.0614 0.3017
Echinococcus granulosus zinc finger protein 0.007 0.0577 0.0577
Trypanosoma cruzi importin beta-1 subunit, putative 0.0081 0.0685 0.3365
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.0079 0.067 0.1041
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0127 0.0772
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0188 0.0188
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0557 0.0557
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0224 0.2037 1
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Onchocerca volvulus 0.0009 0.0006 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0423 0.0423
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0122 0.0169
Echinococcus granulosus titin 0.0011 0.0022 0.0022
Onchocerca volvulus 0.007 0.0584 0.1125
Brugia malayi Bromodomain containing protein 0.0075 0.0633 0.128
Mycobacterium leprae Probable lipase LipE 0.0042 0.0316 0.0498
Schistosoma mansoni hypothetical protein 0.004 0.0297 0.0297
Onchocerca volvulus Huntingtin homolog 0.0136 0.1205 0.2322
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Schistosoma mansoni lozenge 0.0065 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.008 0.0678 0.0678
Schistosoma mansoni aldehyde dehydrogenase 0.0113 0.099 0.099
Brugia malayi Calcitonin receptor-like protein seb-1 0.0117 0.1029 0.2081
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0203 0.0997
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0055 0.0444 0.0444
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0271 0.0271
Mycobacterium ulcerans two component transcriptional regulator 0.0079 0.067 0.1102
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0297 0.0297
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0021 0.0122 0.0102
Echinococcus granulosus liprin alpha 2 0.0027 0.0178 0.0178
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0316 0.0498
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0398 0.3683 0.3683
Brugia malayi beta-lactamase family protein 0.0042 0.0316 0.0638
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0301
Toxoplasma gondii histone lysine methyltransferase SET1 0.0011 0.0023 0.0004
Schistosoma mansoni titin 0.0011 0.0022 0.0022
Brugia malayi Bromodomain containing protein 0.0136 0.1206 0.2439
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Brugia malayi hypothetical protein 0.0136 0.1205 0.2438
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0113 0.099 0.099
Onchocerca volvulus 0.0021 0.0122 0.0235
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0063 0.0517 0.0517
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0021 0.012 0.0589
Brugia malayi Troponin T 0.0074 0.0616 0.1247
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0153 0.1368 0.8557
Brugia malayi beta-lactamase family protein 0.0042 0.0316 0.0638
Loa Loa (eye worm) hypothetical protein 0.0022 0.0124 0.0124
Schistosoma mansoni methyl-cpg binding protein mbd 0.0061 0.0492 0.0492
Loa Loa (eye worm) hypothetical protein 0.0124 0.1094 0.1094
Loa Loa (eye worm) runx1 0.0065 0.0531 0.0531
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0316 0.0433
Echinococcus granulosus kelch ECH associated protein 1 like 0.0105 0.0911 0.0911
Echinococcus multilocularis fetal alzheimer antigen, falz 0.008 0.0677 0.0677
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0557 0.0557
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0122 0.0247
Trypanosoma brucei DNA polymerase IV, putative 0.0017 0.0085 0.0415
Loa Loa (eye worm) hypothetical protein 0.0042 0.0316 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0009 0.0006 0.0012
Trypanosoma brucei unspecified product 0.0017 0.0085 0.0415
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0316 0.0316
Toxoplasma gondii PHD-finger domain-containing protein 0.0067 0.0554 0.3376
Loa Loa (eye worm) hypothetical protein 0.0042 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0054 0.0433 0.0433
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0047 0.0047
Trypanosoma brucei DNA polymerase IV, putative 0.0017 0.0085 0.0415
Schistosoma mansoni topbp1 0.0011 0.0023 0.0023
Brugia malayi hypothetical protein 0.004 0.0297 0.0601
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Schistosoma mansoni jumonji domain containing protein 0.0174 0.1569 0.1569
Mycobacterium ulcerans aldehyde dehydrogenase 0.0113 0.099 0.1646
Echinococcus multilocularis mitogen activated protein kinase 3 0.0177 0.1595 0.1595
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0071
Schistosoma mansoni ephrin receptor 0.0011 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0316 0.155
Schistosoma mansoni myelin transcription factor 1 myt1 0.0063 0.0517 0.0517
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0017 0.0085 0.0085
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0073 0.0614 0.0614
Echinococcus granulosus apoptotic protease activating factor 1 0.0143 0.1269 0.1269
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0271 0.0271
Schistosoma mansoni phosphatidylserine receptor 0.0022 0.0124 0.0124
Echinococcus multilocularis importin 5 0.0019 0.0098 0.0098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0131 0.1157 0.1157
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0006 0.0006
Echinococcus multilocularis geminin 0.0399 0.369 0.369
Echinococcus granulosus titin 0.0011 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0316 0.0316
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0022 0.0124 0.0644
Schistosoma mansoni microtubule-associated protein tau 0.0827 0.7742 0.7742
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0006 0.0006
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0212 0.1925 0.1925
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0178
Brugia malayi Troponin family protein 0.0124 0.1094 0.2213
Leishmania major hypothetical protein, conserved 0.0042 0.0316 0.155
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0016 0.0071 1
Schistosoma mansoni ephrin receptor 0.0229 0.2082 0.2082
Trypanosoma brucei ISWI complex protein 0.0054 0.0433 0.2128
Schistosoma mansoni jumonji domain containing protein 0.0022 0.0124 0.0124
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Schistosoma mansoni hypothetical protein 0.0073 0.0613 0.0613
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0153 0.1368 0.2767
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0006 0.0012
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0079 0.067 0.1041
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0122 0.0169
Schistosoma mansoni sarm1 0.0027 0.0178 0.0178
Echinococcus granulosus caspase 0.0405 0.375 0.375
Onchocerca volvulus 0.0042 0.0316 0.0608
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0153 0.1368 0.1368
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0316 0.0566
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0088 0.0751 0.0751
Brugia malayi photoreceptor-specific nuclear receptor 0.0009 0.0006 0.0012
Echinococcus multilocularis PHD finger protein rhinoceros 0.0067 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0203
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0033 0.0164
Trypanosoma brucei metacaspase MCA2 0.0153 0.1368 0.6718
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0022 0.0124 0.0644
Trypanosoma brucei importin beta-1 subunit, putative 0.01 0.0864 0.4242
Brugia malayi Troponin T 0.0074 0.0616 0.1247
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0009 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0081 0.0685 0.3289
Echinococcus multilocularis SAM domain containing protein 0.0027 0.0178 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0113 0.099 0.1646
Trichomonas vaginalis set domain proteins, putative 0.0557 0.519 1
Toxoplasma gondii HEAT repeat-containing protein 0.01 0.0864 0.5349
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0006 0.0006
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0074 0.062 0.0955
Brugia malayi AF-10 protein 0.0022 0.0127 0.0256
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0017 0.0085 0.0037
Echinococcus granulosus geminin 0.0399 0.369 0.369
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.0557 0.1126
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.017 0.0833
Schistosoma mansoni tsg101-related 0.0132 0.1164 0.1164
Brugia malayi latrophilin 2 splice variant baaae 0.008 0.0678 0.1371
Trypanosoma cruzi ISWI complex protein 0.0054 0.0433 0.2128
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0188 0.0188
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Loa Loa (eye worm) hypothetical protein 0.0124 0.1094 0.1094
Entamoeba histolytica hypothetical protein 0.0026 0.017 0.0729
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0268 0.245 0.4091
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0009 0.0006 0.0012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.022 0.1996 0.1996
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0557 0.0909
Schistosoma mansoni hypothetical protein 0.0143 0.1269 0.1269
Trichomonas vaginalis CAMK family protein kinase 0.0224 0.2037 0.3897
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0009 0.0006 0.0006
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.0079 0.067 0.1102
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0009 0.0006 0.0006
Trypanosoma cruzi FHA domain containing protein, putative 0.0011 0.0023 0.0112
Echinococcus multilocularis kelch ECH associated protein 1 0.0105 0.0911 0.0911
Plasmodium vivax tyrosine kinase-like protein, putative 0.003 0.0202 0.1331
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0177 0.1595 0.7832
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.049 0.4551 0.4551
Onchocerca volvulus 0.0531 0.4944 0.9525
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0177 0.1595 0.7832
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.1595 0.1595
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0122 0.0169
Echinococcus granulosus histone lysine methyltransferase setb 0.0131 0.1157 0.1157
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Echinococcus multilocularis titin 0.0011 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0122 0.0247
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0584 0.0584
Echinococcus multilocularis kelch ECH associated protein 1 0.0105 0.0911 0.0911
Brugia malayi RNA, U transporter 1 0.0284 0.2605 0.5268
Leishmania major importin beta-1 subunit, putative 0.0081 0.0685 0.3365
Schistosoma mansoni troponin I 0.0124 0.1094 0.1094
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0073 0.0614 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0301
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0006 0.0012
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0154 0.1379 0.2309
Schistosoma mansoni caspase-7 (C14 family) 0.0296 0.2717 0.2717
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.1368 0.2603
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0316 0.0566
Echinococcus multilocularis histone acetyltransferase MYST2 0.0063 0.0517 0.0517
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0073 0.0614 0.3017
Mycobacterium tuberculosis Probable transcriptional regulatory protein (LuxR-family) 0.0079 0.067 0.1041
Loa Loa (eye worm) hypothetical protein 0.0226 0.2058 0.2058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0423 0.0423
Trichomonas vaginalis DNA polymerase eta, putative 0.0017 0.0085 0.0119
Echinococcus multilocularis microtubule associated protein 2 0.0827 0.7742 0.7742
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0085 0.0085
Brugia malayi jmjC domain containing protein 0.022 0.1996 0.4037
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0027 0.0178 0.0301
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0316 0.0316
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0316 0.0433
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0071
Schistosoma mansoni RAR-like nuclear receptor 0.0009 0.0006 0.0006
Plasmodium vivax importin-beta 2, putative 0.01 0.0864 0.6251
Schistosoma mansoni hypothetical protein 0.0124 0.1094 0.1094
Schistosoma mansoni sex comb on midleg homolog 0.0055 0.0444 0.0444
Loa Loa (eye worm) hypothetical protein 0.0515 0.4792 0.4792
Loa Loa (eye worm) jmjC domain-containing protein 0.0088 0.0751 0.0751
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0316 0.2176
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.007 0.0584 0.3568
Plasmodium falciparum JmjC domain-containing protein, putative 0.0022 0.0124 0.0753
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0033 0.0164
Loa Loa (eye worm) hypothetical protein 0.0074 0.0616 0.0616
Echinococcus granulosus tankyrase 0.0027 0.0178 0.0178
Echinococcus multilocularis oncosphere protein tso22e oncosphere protein tso22d oncosphere protein tso22c oncosphere protein tso22b oncosphere protein tso22 0.0154 0.1377 0.1377
Loa Loa (eye worm) hypothetical protein 0.0478 0.4441 0.4441
Echinococcus granulosus ephrin type A receptor 4 A 0.0229 0.2082 0.2082
Mycobacterium ulcerans hypothetical protein 0.0079 0.067 0.1102
Plasmodium falciparum tyrosine kinase-like protein 0.003 0.0202 0.1331
Brugia malayi hypothetical protein 0.0515 0.4792 0.9692
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0006 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0022 0.0022
Echinococcus granulosus lysine specific demethylase 6a 0.0022 0.0124 0.0124
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0158 0.1414 0.1414
Echinococcus granulosus caspase 8 0.0153 0.1368 0.1368
Schistosoma mansoni methyl-cpg binding protein mbd 0.0061 0.0492 0.0492
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0423 0.0423
Onchocerca volvulus Alhambra homolog 0.0067 0.0554 0.1067
Schistosoma mansoni ran 0.0073 0.0614 0.0614
Echinococcus granulosus translational activator gcn1 0.0019 0.0098 0.0098
Schistosoma mansoni topbp1 0.0011 0.0023 0.0023
Brugia malayi jmjC domain containing protein 0.0022 0.0124 0.0251
Loa Loa (eye worm) hypothetical protein 0.0016 0.0071 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.0022 0.0124 0.0124
Plasmodium vivax JmjC domain containing protein 0.0022 0.0124 0.0753
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0009 0.0006 0.0006
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0006 0.0012
Schistosoma mansoni phd/f-box containing protein 0.0022 0.0124 0.0124
Brugia malayi Importin beta-1 subunit 0.01 0.0864 0.1747
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Loa Loa (eye worm) hypothetical protein 0.0022 0.0124 0.0124
Loa Loa (eye worm) PHD-finger family protein 0.0073 0.0613 0.0613
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0975 0.1843
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0122 0.0169
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0021 0.0122 0.0169
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0316 0.0498
Onchocerca volvulus 0.0042 0.0316 0.0608
Echinococcus granulosus GTP binding nuclear protein Ran 0.0073 0.0614 0.0614
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0073 0.0614 0.2938
Onchocerca volvulus 0.0042 0.0316 0.0608
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0011 0.0022 0.0022
Brugia malayi ecdysteroid receptor 0.0009 0.0006 0.0012
Loa Loa (eye worm) mbt repeat family protein 0.0055 0.0444 0.0444
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0071 0.0082
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0061 0.0492 0.0492
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0153 0.1368 0.8557
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0009 0.0006 0.0006
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0177 0.1595 0.1595
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.1368 0.2603
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0177 0.1595 0.7832
Schistosoma mansoni hypothetical protein 0.0337 0.3109 0.3109
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0316 0.0498
Echinococcus multilocularis Protein lozenge 0.0065 0.0531 0.0531
Echinococcus multilocularis caspase 3 0.0252 0.2301 0.2301
Echinococcus granulosus JmjC domain containing protein 4 0.0022 0.0124 0.0124
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.01 0.0864 0.0864
Echinococcus multilocularis tankyrase 0.0027 0.0178 0.0178
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0027 0.0178 0.0178
Onchocerca volvulus 0.0011 0.0023 0.0044
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0051 0.0398 0.1952
Mycobacterium tuberculosis Conserved protein 0.0042 0.0316 0.0433
Echinococcus multilocularis dna polymerase kappa 0.0017 0.0085 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0224 0.2037 0.3897
Loa Loa (eye worm) hypothetical protein 0.0042 0.0316 0.0316
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0006 0.0006
Brugia malayi hypothetical protein 0.0019 0.0103 0.0208
Plasmodium falciparum transportin 0.0019 0.0098 0.0559
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Brugia malayi DKFZp564C0469 protein 0.0011 0.0023 0.0046
Trypanosoma brucei metacaspase 5, putative 0.0153 0.1368 0.6718
Leishmania major 4-coumarate:coa ligase-like protein 0.0021 0.0122 0.06
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0632 0.5898 1
Echinococcus multilocularis importin subunit beta 1 0.01 0.0864 0.0864
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0632 0.5898 1
Leishmania major hypothetical protein, conserved 0.003 0.0203 0.0997
Schistosoma mansoni hypothetical protein 0.0027 0.0178 0.0178
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0016 0.0071 0.0014
Schistosoma mansoni hypothetical protein 0.0037 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0296 0.2717 0.2717
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0011 0.0023 0.5
Brugia malayi hypothetical protein 0.0027 0.0178 0.0361
Plasmodium falciparum acyl-CoA synthetase 0.0016 0.0071 0.0358
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0316 0.0316
Brugia malayi serine/threonine-protein kinase plk-2 0.0224 0.2037 0.4119
Leishmania major metacaspase, putative 0.0153 0.1368 0.6718
Loa Loa (eye worm) MBCTL1 0.0063 0.0517 0.0517
Leishmania major hypothetical protein, conserved 0.0054 0.0433 0.2128
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0009 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.004 0.0297 0.1362
Leishmania major hypothetical protein, conserved 0.0019 0.0098 0.0482
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0085 0.0085
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0316 0.0316
Trypanosoma cruzi ISWI complex protein 0.0054 0.0433 0.2128
Entamoeba histolytica serine/threonine protein kinase, putative 0.0224 0.2037 1
Echinococcus multilocularis liprin beta 1 0.0027 0.0178 0.0178
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.007 0.0584 0.0584
Brugia malayi hypothetical protein 0.0158 0.1414 0.2861
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0203 0.0997
Trichomonas vaginalis CAMK family protein kinase 0.0224 0.2037 0.3897
Plasmodium vivax hypothetical protein, conserved 0.0153 0.1368 1
Entamoeba histolytica Ran family GTPase 0.0073 0.0614 0.2938
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0405 0.375 0.375
Schistosoma mansoni hypothetical protein 0.0013 0.0047 0.0047
Entamoeba histolytica acyl-coA synthetase, putative 0.0021 0.0122 0.0494
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0128 0.1126 0.1126
Schistosoma mansoni caspase-3 (C14 family) 0.0405 0.375 0.375
Echinococcus multilocularis transportin 1 0.0019 0.0098 0.0098
Echinococcus granulosus polycomb protein SCMH1 0.0055 0.0444 0.0444
Onchocerca volvulus 0.0055 0.0444 0.0856
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Schistosoma mansoni hypothetical protein 0.0037 0.0271 0.0271
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0557 0.0909
Loa Loa (eye worm) hypothetical protein 0.0021 0.0122 0.0122
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0009 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Echinococcus multilocularis nibrin 0.0011 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Schistosoma mansoni steroid hormone receptor ad4bp 0.0009 0.0006 0.0006
Echinococcus granulosus stromal interaction molecule 1 0.0027 0.0178 0.0178
Echinococcus granulosus kelch ECH associated protein 1 like 0.0105 0.0911 0.0911
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.017 0.0833
Brugia malayi jmjC domain containing protein 0.0022 0.0124 0.0251
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0011 0.0024 0.0024
Brugia malayi Pre-SET motif family protein 0.049 0.4551 0.9204
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.022 0.1996 0.1996
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0.0023 0.0046
Schistosoma mansoni hypothetical protein 0.0399 0.369 0.369
Trypanosoma cruzi DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0073 0.0614 0.1243
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0073 0.0614 0.3017
Loa Loa (eye worm) hypothetical protein 0.0145 0.1288 0.1288
Giardia lamblia DINP protein human, muc B family 0.0017 0.0085 0.0306
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0085 0.0415
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0022 0.0127 0.0661
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0178
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0316 0.0433
Trichomonas vaginalis hypothetical protein 0.0077 0.0648 0.1209
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0122 0.0494
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0398 0.3683 0.3683
Loa Loa (eye worm) steroid hormone receptor 0.0009 0.0006 0.0006
Schistosoma mansoni peptidase 0.0009 0.0006 0.0006
Schistosoma mansoni bromodomain containing protein 0.0225 0.2045 0.2045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0006 0.0012
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0423 0.0423
Echinococcus multilocularis dna polymerase eta 0.0017 0.0085 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0009 0.0006 0.0012
Schistosoma mansoni lip-related protein (liprin) alpha 0.0027 0.0178 0.0178
Brugia malayi hypothetical protein 0.0011 0.0023 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0122 0.0247
Schistosoma mansoni hypothetical protein 0.0037 0.0271 0.0271
Onchocerca volvulus 0.0027 0.0178 0.0343
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0113 0.099 0.099
Echinococcus granulosus histone acetyltransferase MYST2 0.0063 0.0517 0.0517
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0023 0.0112
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Echinococcus granulosus jumonji domain containing protein 0.0093 0.0802 0.0802
Toxoplasma gondii HEAT repeat-containing protein 0.0019 0.0098 0.0479
Loa Loa (eye worm) hypothetical protein 0.0029 0.0191 0.0191
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0316 0.0566
Brugia malayi MAP kinase sur-1 0.0177 0.1595 0.3226
Echinococcus granulosus kelch ECH associated protein 1 0.0105 0.0911 0.0911
Loa Loa (eye worm) hypothetical protein 0.0136 0.1208 0.1208
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0316 0.0566
Loa Loa (eye worm) hypothetical protein 0.0055 0.0444 0.0444
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0219 0.1987 0.1987
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0009 0.0006 0.0006
Onchocerca volvulus 0.0515 0.4792 0.9232
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0481 0.0481
Mycobacterium ulcerans lipoprotein LpqF 0.0074 0.062 0.1017
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.1595 0.3042
Echinococcus multilocularis caspase 0.0405 0.375 0.375
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0219 0.1987 0.1987
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0068 0.0559 0.0559
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.1368 0.2603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0423 0.0423
Schistosoma mansoni aldehyde dehydrogenase 0.0113 0.099 0.099
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0067 0.0554 0.0554
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0009 0.0006 0.0012
Echinococcus granulosus caspase 3 0.0252 0.2301 0.2301
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.1595 0.3042
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Onchocerca volvulus 0.0012 0.0032 0.0062
Plasmodium falciparum metacaspase-like protein 0.0153 0.1368 1
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.1595 0.3042
Loa Loa (eye worm) troponin I 0.0124 0.1094 0.1094
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0271 0.0271
Trypanosoma brucei metacaspase 0.0153 0.1368 0.6718
Echinococcus multilocularis ecdysone induced protein 78C 0.0009 0.0006 0.0006
Mycobacterium ulcerans putative regulatory protein 0.0079 0.067 0.1102
Brugia malayi Pre-SET motif family protein 0.007 0.0584 0.1181
Schistosoma mansoni protein phosphatase 2C 0.0022 0.0124 0.0124
Brugia malayi steroid hormone receptor 0.0009 0.0006 0.0012
Schistosoma mansoni troponin I 0.0124 0.1094 0.1094
Loa Loa (eye worm) hypothetical protein 0.0136 0.1205 0.1205
Schistosoma mansoni zinc finger protein 0.007 0.0577 0.0577
Echinococcus multilocularis troponin i 0.0124 0.1094 0.1094
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0081 0.0685 0.1282
Echinococcus granulosus lysine specific demethylase 5A 0.0088 0.0751 0.0751
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0085 0.0085
Plasmodium falciparum phd finger protein, putative 0.0067 0.0554 0.3945
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0011 0.0024 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0153 0.1368 0.2603
Schistosoma mansoni coup transcription factor 0.0009 0.0006 0.0006
Mycobacterium ulcerans DNA polymerase IV 0.0017 0.0085 0.0105
Schistosoma mansoni hypothetical protein 0.0067 0.0554 0.0554
Schistosoma mansoni DNA ligase IV 0.0011 0.0023 0.0023
Brugia malayi Steroid receptor seven-up type 2 0.0009 0.0006 0.0012
Leishmania major hypothetical protein, conserved 0.0022 0.0124 0.061
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0122 0.0169
Schistosoma mansoni troponin t invertebrate 0.0154 0.1377 0.1377
Loa Loa (eye worm) troponin T 0.0074 0.0616 0.0616
Mycobacterium ulcerans DNA polymerase IV 0.0017 0.0085 0.0105
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0131 0.1157 0.1157
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0177 0.1595 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0009 0.0006 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0023 0.0112
Leishmania major hypothetical protein, conserved 0.0051 0.0398 0.1952
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0122 0.0494
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0271 0.0547
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0316 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0009 0.0006 0.0012
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0085 0.0085
Brugia malayi jmjC domain containing protein 0.0088 0.0751 0.1519
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0027 0.0178 0.0178
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Loa Loa (eye worm) hypothetical protein 0.0011 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0037 0.0271 0.0271
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.1595 0.3042
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0632 0.5898 1
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.0079 0.067 0.1041
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0022 0.0124 0.061
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0006 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0009 0.0006 0.0006
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0026 0.017 0.0729
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.1368 0.2603
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0085 0.0415
Loa Loa (eye worm) hypothetical protein 0.0515 0.4792 0.4792
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.017 0.0284
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0006
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.003 0.02 0.1128
Schistosoma mansoni tsg101-related 0.0132 0.1164 0.1164
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0127 0.0772
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0122 0.0102
Trypanosoma cruzi metacaspase, putative 0.0153 0.1368 0.6718
Trypanosoma cruzi polo-like protein kinase, putative 0.0224 0.2037 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0224 0.2037 0.3924
Loa Loa (eye worm) PHD-finger family protein 0.0067 0.0554 0.0554
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.017 0.0833
Loa Loa (eye worm) jmjC domain-containing protein 0.0138 0.1229 0.1229
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0022 0.0127 0.0622
Trichomonas vaginalis esterase, putative 0.0042 0.0316 0.0566
Entamoeba histolytica hypothetical protein 0.0026 0.017 0.0729
Loa Loa (eye worm) hypothetical protein 0.0131 0.1157 0.1157
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0423 0.0423
Toxoplasma gondii ABC1 family protein 0.0042 0.0316 0.1862
Schistosoma mansoni bromodomain containing protein 0.0015 0.0063 0.0063

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) Growth inhibition of Escherichia coli DH5alpha (pJN105L + pSC11) at 10 uM after 4 to 16 hrs ChEMBL. 21798746
Activity (functional) = 0 % Agonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR at 10 uM after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHL ChEMBL. 21798746
Activity (functional) = 0 % Agonist activity at Agrobacterium tumefaciens WCF (pCF372) TraR at 10 uM after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHL ChEMBL. 21798746
Activity (functional) = 20 % Agonist activity at Pseudomonas aeruginosa PAO1 MW1 (pUM15) LasR at 10 uM after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHL ChEMBL. 21798746
IC50 (functional) = 0.84 uM Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by beta-galactosidase reporter gene assay ChEMBL. 21798746
Inhibition (functional) = -78 % Antagonist activity at Agrobacterium tumefaciens WCF (pCF372) TraR assessed as inhibition of OdDHL-induced quorum sensing activation at 10 uM after 8 hrs by beta-galactosidase reporter gene assay relative to untreated control ChEMBL. 21798746
Inhibition (functional) = -23 % Antagonist activity at Pseudomonas aeruginosa PAO1 MW1 (pUM15) LasR assessed as inhibition of OdDHL-induced quorum sensing activation at 10 uM after 8 hrs by beta-galactosidase reporter gene assay relative to untreated control ChEMBL. 21798746
Inhibition (functional) = 93 % Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation at 10 uM after 8 hrs by beta-galactosidase reporter gene assay relative to untreated control ChEMBL. 21798746

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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