Detailed information for compound 1123161

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 373.406 | Formula: C18H23N5O4
  • H donors: 4 H acceptors: 6 LogP: 0.43 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1OC([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCC1CC2CC1C=C2
  • InChi: 1S/C18H23N5O4/c24-6-12-14(25)15(26)18(27-12)23-8-22-13-16(20-7-21-17(13)23)19-5-11-4-9-1-2-10(11)3-9/h1-2,7-12,14-15,18,24-26H,3-6H2,(H,19,20,21)/t9?,10?,11?,12-,14-,15-,18?/m1/s1
  • InChiKey: HOIMDJVHLZFLPK-PPOBMEROSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0174 0.0282
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0174 0.0279
Trypanosoma brucei glucose transporter 1E 0.0032 0.0304 0.1762
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0304 0.0507
Schistosoma mansoni carbonyl reductase 0.0012 0.001 0.004
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0174 0.0237
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Echinococcus multilocularis lamin 0.0028 0.024 0.0333
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0028 0.0241 0.0334
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Onchocerca volvulus 0.0014 0.0049 0.0068
Onchocerca volvulus 0.0014 0.0049 0.0068
Brugia malayi major facilitator superfamily protein 0.0014 0.0049 0.0057
Onchocerca volvulus 0.0014 0.0049 0.0068
Onchocerca volvulus 0.0014 0.0049 0.0068
Onchocerca volvulus 0.0014 0.0049 0.0068
Onchocerca volvulus 0.0014 0.0049 0.0068
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0586 0.0834
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0304 0.0507
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0685 0.0989
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0174 0.0274
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0174 0.0237
Loa Loa (eye worm) hypothetical protein 0.0013 0.0025 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.1429 0.8492
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0156 0.0381
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Leishmania major hypothetical protein, conserved 0.0014 0.0049 0.0237
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0049 0.0057
Schistosoma mansoni glucose transport protein 0.0103 0.1341 0.5497
Mycobacterium ulcerans lipase LipD 0.0109 0.1429 0.2444
Plasmodium vivax hexose transporter 0.0103 0.1341 0.2157
Onchocerca volvulus 0.0109 0.1429 0.2444
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.013 0.0173
Schistosoma mansoni hypothetical protein 0.0178 0.244 1
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0126 0.1681 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0049 0.0068
Echinococcus granulosus calcium dependent protein kinase 0.003 0.027 0.0376
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0049 0.0057
Loa Loa (eye worm) hypothetical protein 0.0053 0.0606 0.0874
Echinococcus multilocularis BRK domain containing protein 0.0013 0.0022 0.0017
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0064 0.0325
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0156 0.0211
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Toxoplasma gondii methionine aminopeptidase 0.0028 0.0241 0.059
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.098 0.1402
Brugia malayi hypothetical protein 0.0053 0.0606 0.0861
Loa Loa (eye worm) methionine aminopeptidase type I 0.0044 0.0474 0.0684
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0409 0.5816 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0123 0.0113
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Onchocerca volvulus 0.0014 0.0049 0.0068
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0299 0.0475
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0304 0.1762
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0299 0.0731
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0231 0.1562
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.1576 0.2698
Brugia malayi hypothetical protein 0.0485 0.6927 1
Brugia malayi beta-lactamase family protein 0.0109 0.1429 0.2051
Echinococcus multilocularis BRK domain containing protein 0.0013 0.0022 0.0017
Brugia malayi Doublecortin family protein 0.002 0.013 0.0173
Plasmodium vivax JmjC domain containing protein 0.0015 0.0064 0.0103
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Trichomonas vaginalis esterase, putative 0.0109 0.1429 0.2444
Schistosoma mansoni hypothetical protein 0.0103 0.1341 0.5497
Echinococcus multilocularis lamin dm0 0.0028 0.024 0.0333
Loa Loa (eye worm) hypothetical protein 0.0027 0.0233 0.0336
Trypanosoma cruzi hexose transporter 0.0032 0.0304 0.1762
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0289 0.0481
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0298 0.0431
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.0064 0.0079
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0409 0.5816 1
Plasmodium falciparum hexose transporter 0.0103 0.1341 0.2153
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0304 0.1762
Onchocerca volvulus Huntingtin homolog 0.0123 0.1633 0.2795
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0049 0.0121
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0071 0.0366
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0409 0.5816 1
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0126 0.1681 0.2878
Mycobacterium tuberculosis Probable hydrolase 0.0109 0.1429 0.142
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.1017 0.1468
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0299 0.0731
Mycobacterium leprae conserved hypothetical protein 0.0109 0.1429 1
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0654 0.0931
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0364 0.0585
Trichomonas vaginalis inositol monophosphatase, putative 0.0079 0.0997 0.17
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0044 0.0474 0.0671
Loa Loa (eye worm) hypothetical protein 0.0028 0.024 0.0347
Loa Loa (eye worm) hypothetical protein 0.0015 0.0064 0.0093
Loa Loa (eye worm) sugar transporter 0.0103 0.1341 0.1936
Onchocerca volvulus 0.0014 0.0049 0.0068
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.098 0.6836
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.1341 0.1924
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0606 0.0969
Toxoplasma gondii methionine aminopeptidase 0.0044 0.0474 0.116
Trypanosoma cruzi hypothetical protein, conserved 0.0126 0.1681 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0298 0.0417
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.098 0.1571
Echinococcus multilocularis solute carrier family 22 0.0014 0.0049 0.0057
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0298 0.0417
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0166 0.2267 0.555
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0107 0.1401 0.2409
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0174 0.0282
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1208 0.4952
Brugia malayi intermediate filament protein 0.0028 0.024 0.0333
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0064 0.0079
Mycobacterium tuberculosis Probable esterase LipL 0.0109 0.1429 0.142
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.001 0.0024
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0109 0.1429 0.142
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0409 0.5816 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0409 0.5816 1
Mycobacterium tuberculosis Probable lipase LipE 0.0109 0.1429 0.142
Giardia lamblia Sugar-proton symporter 0.0014 0.0049 0.0068
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0079 0.0997 0.17
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0299 0.0475
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.1341 0.1924
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0283 0.3973 0.3967
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0064 0.0079
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.1017 0.1456
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0174 0.0712
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0044 0.0474 0.2776
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0174 0.1155
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0304 0.1762
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0156 0.0381
Loa Loa (eye worm) hypothetical protein 0.0485 0.6927 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Mycobacterium tuberculosis Conserved protein 0.0109 0.1429 0.142
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0064 0.0263
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0156 0.0873
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.098 0.1576
Loa Loa (eye worm) hypothetical protein 0.0123 0.1633 0.2357
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0231 0.0367
Brugia malayi hypothetical protein 0.0014 0.0049 0.0057
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0409 0.5816 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0606 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0298 0.0497
Toxoplasma gondii oxidoreductase, putative 0.0012 0.001 0.0024
Toxoplasma gondii sugar transporter ST3 0.0014 0.0049 0.0121
Schistosoma mansoni hypothetical protein 0.0013 0.0022 0.009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0255 0.3565 0.5139
Echinococcus granulosus Chromo domain 0.0013 0.0022 0.0018
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0289 0.1968
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0064 0.0093
Onchocerca volvulus 0.0099 0.1284 0.2195
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Leishmania major hypothetical protein, conserved 0.0053 0.0606 0.3566
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Trypanosoma brucei metallo- peptidase, Clan MG, Family M24 0.0044 0.0474 0.2776
Toxoplasma gondii sugar transporter ST1 0.0014 0.0049 0.0121
Echinococcus granulosus global transcription activator snf2l2 0.0073 0.09 0.1286
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0011 0.0003 0.0009
Brugia malayi hypothetical protein 0.0014 0.0049 0.0057
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Onchocerca volvulus 0.0014 0.0049 0.0068
Echinococcus multilocularis General substrate transporter 0.0088 0.113 0.1619
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.001 0.0024
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0409 0.5816 0.8393
Schistosoma mansoni glucose transporter 0.0014 0.0049 0.0203
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0174 0.098
Loa Loa (eye worm) hypothetical protein 0.002 0.013 0.0187
Plasmodium vivax methionine aminopeptidase 1b, putative 0.0044 0.0474 0.0762
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0156 0.0251
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.001 0.001
Onchocerca volvulus 0.0014 0.0049 0.0068
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0064 0.0263
Schistosoma mansoni retinal dehydrogenase 0.0012 0.001 0.004
Plasmodium falciparum protein kinase 6 0.0437 0.6217 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0109 0.1429 0.142
Onchocerca volvulus 0.002 0.013 0.0206
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0304 0.0507
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0417
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0049 0.0057
Schistosoma mansoni hypothetical protein 0.0081 0.1017 0.4169
Onchocerca volvulus 0.0014 0.0049 0.0068
Echinococcus granulosus inositol monophosphatase 1 0.0079 0.0997 0.1427
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0174 0.0237
Onchocerca volvulus 0.0014 0.0049 0.0068
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0231 0.2363
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0156 0.0211
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0079 0.0997 0.17
Onchocerca volvulus 0.0014 0.0049 0.0068
Toxoplasma gondii hypothetical protein 0.0016 0.0071 0.0174
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0084 0.1069 0.1838
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.1576 0.2698
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.1429 0.8492
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.1341 0.1924
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0289 0.0497
Toxoplasma gondii hypothetical protein 0.0027 0.0231 0.0567
Brugia malayi BRM protein 0.0073 0.09 0.1286
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.1429 0.2444
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0126 0.1681 0.2878
Loa Loa (eye worm) hypothetical protein 0.0081 0.1017 0.1468
Mycobacterium tuberculosis Conserved protein 0.0109 0.1429 0.142
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.001 0.0017
Echinococcus granulosus RUN 0.002 0.013 0.0173
Echinococcus multilocularis inositol monophosphatase 1 0.0079 0.0997 0.1427
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0298 0.0417
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.1341 0.1924
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0304 0.1762
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) 0.0028 0.0241 0.1628
Loa Loa (eye worm) hypothetical protein 0.0109 0.1429 0.2062
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0409 0.5816 1
Echinococcus granulosus intermediate filament protein 0.0028 0.024 0.0333
Toxoplasma gondii protein kinase, putative 0.0291 0.4084 1
Toxoplasma gondii ABC1 family protein 0.0109 0.1429 0.3498
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.1429 0.2444
Leishmania major glucose transporter, lmgt1 0.0032 0.0304 0.1762
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.001 0.004
Brugia malayi Sugar transporter family protein 0.0103 0.1341 0.1924
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0289 0.0404
Echinococcus multilocularis BRK domain containing protein 0.0013 0.0022 0.0017
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.001 0.0016
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0299 0.048
Schistosoma mansoni hypothetical protein 0.0099 0.1284 0.5263
Onchocerca volvulus 0.0014 0.0049 0.0068
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0298 0.0417
Echinococcus multilocularis BRK domain containing protein 0.0013 0.0022 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.1429 0.8492
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Loa Loa (eye worm) inositol-1 0.0079 0.0997 0.1439
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0109 0.1429 0.142
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.001 0.004
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.1017 0.1456
Brugia malayi major facilitator superfamily protein 0.0014 0.0049 0.0057
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.098 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.098 0.1414
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0298 0.1223
Toxoplasma gondii carbonyl reductase 1, putative 0.0012 0.001 0.0024
Echinococcus granulosus methionyl aminopeptidase 1 M24 family 0.0044 0.0474 0.0671
Plasmodium falciparum methionine aminopeptidase 1b, putative 0.0044 0.0474 0.0757
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.1429 0.2444
Brugia malayi Calcitonin receptor-like protein seb-1 0.0255 0.3565 0.5139
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0304 0.0507
Echinococcus multilocularis BRK domain containing protein 0.0013 0.0022 0.0017
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Onchocerca volvulus 0.0014 0.0049 0.0068
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Echinococcus granulosus GPCR family 2 0.0081 0.1017 0.1456
Echinococcus granulosus BRK domain containing protein 0.0013 0.0022 0.0017
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0156 0.0245
Toxoplasma gondii sugar transporter ST2 0.0014 0.0049 0.0121
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.001 0.001
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Schistosoma mansoni lipoxygenase 0.0056 0.0654 0.2681
Mycobacterium ulcerans sugar transporter 0.0014 0.0049 0.0068
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0049 0.0057
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0409 0.5816 1
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0028 0.0241 0.0987
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0071 0.0876 0.6101
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0064 0.0079
Brugia malayi Latrophilin receptor protein 2 0.0081 0.1017 0.1456
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0012 0.001 0.0017
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0586 0.0577
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Echinococcus granulosus bloom syndrome protein 0.0022 0.0156 0.0211
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0064 0.0093
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.1429 0.5856
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0079 0.0997 0.17
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0174 0.098
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0654 0.0931
Leishmania major glucose transporter, lmgt2 0.0032 0.0304 0.1762
Schistosoma mansoni hypothetical protein 0.0178 0.244 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.1576 0.2264
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0182 0.025
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0023 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Brugia malayi jmjC domain containing protein 0.0015 0.0064 0.0079
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.013 0.0173
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.013 0.0173
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.2385 0.3434
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Plasmodium vivax sugar transporter, putative 0.0014 0.0049 0.008
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Schistosoma mansoni polycystin 1-related 0.002 0.013 0.0531
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0109 0.1429 0.2444
Chlamydia trachomatis methionine aminopeptidase 0.0028 0.0241 0.0834
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.1341 0.1924
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.024 0.0347
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.013 0.0173
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Echinococcus multilocularis BRK domain 0.0013 0.0022 0.0017
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Schistosoma mansoni survival motor neuron protein 0.0099 0.1284 0.5263
Plasmodium vivax CDK-related protein kinase 6, putative 0.0437 0.6217 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0071 0.0114
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0586 0.0834
Echinococcus multilocularis survival motor neuron protein 1 0.0485 0.6927 1
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0053 0.0063
Onchocerca volvulus 0.0028 0.024 0.0397
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0049 0.0068
Treponema pallidum methionine aminopeptidase (map) 0.0028 0.0241 0.2458
Brugia malayi hypothetical protein 0.002 0.013 0.0173
Onchocerca volvulus Putative transporter 0.0014 0.0049 0.0068
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0298 0.0417
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0174 0.0282
Mycobacterium ulcerans beta-lactamase 0.0109 0.1429 0.2444
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0028 0.0241 0.0987
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0049 0.0057
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0298 0.0431
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.1429 0.2444
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.1429 0.5856
Plasmodium falciparum HP12 protein homolog, putative 0.0016 0.0071 0.0109
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.1341 0.1924
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0299 0.0475
Plasmodium falciparum protein kinase 7 0.0291 0.4084 0.6568
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0255 0.3565 0.5146
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0997 0.5908
Loa Loa (eye worm) BRM protein 0.0046 0.0516 0.0745
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0299 0.048
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0166 0.2267 0.3646
Leishmania major protein kinase, putative 0.0032 0.0298 0.1727
Brugia malayi hypothetical protein 0.0123 0.1633 0.2346
Loa Loa (eye worm) hypothetical protein 0.0109 0.1429 0.2062
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0032 0.0032
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0298 0.0417
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0685 0.2809
Echinococcus granulosus survival motor neuron protein 1 0.0485 0.6927 1
Schistosoma mansoni hypothetical protein 0.0174 0.2385 0.9778
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0064 0.0263
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0049 0.0402
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0064 0.0263
Loa Loa (eye worm) sugar transporter 0.0014 0.0049 0.0071
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0049 0.0071
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0132 0.0211
Loa Loa (eye worm) hypothetical protein 0.0109 0.1429 0.2062
Onchocerca volvulus 0.0014 0.0049 0.0068
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0156 0.0873
Loa Loa (eye worm) hypothetical protein 0.0109 0.1429 0.2062
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0606 0.3566
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.024 0.0333
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0289 0.0404
Onchocerca volvulus 0.0109 0.1429 0.2444
Brugia malayi jmjC domain containing protein 0.0058 0.0685 0.0977
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Leishmania major hypothetical protein, conserved 0.0015 0.0064 0.0325
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0174 0.0712
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0064 0.0157
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0064 0.0079
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.0064 0.0079
Loa Loa (eye worm) hypothetical protein 0.0022 0.0156 0.0225
Mycobacterium ulcerans methionine aminopeptidase 0.0028 0.0241 0.0398
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Echinococcus granulosus solute carrier family 22 0.0014 0.0049 0.0057
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.1017 0.1456
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0049 0.0203
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0409 0.5816 0.8395
Schistosoma mansoni lamin 0.0028 0.024 0.0984
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0123 0.0798
Brugia malayi beta-lactamase 0.0109 0.1429 0.2051
Brugia malayi Methionine aminopeptidase protein type I 0.0044 0.0474 0.0671
Onchocerca volvulus 0.0109 0.1429 0.2444
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0049 0.0237
Echinococcus multilocularis solute carrier family 22 0.0014 0.0049 0.0057
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0156 0.0268
Onchocerca volvulus 0.0409 0.5816 1
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Onchocerca volvulus 0.0028 0.024 0.0397
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0289 0.0404
Brugia malayi Sugar transporter family protein 0.0014 0.0049 0.0057
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0299 0.048
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0079 0.0997 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0049 0.0068
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0049 0.004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0109 0.1429 0.2051
Schistosoma mansoni sugar transporter 0.0014 0.0049 0.0203
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0298 0.0417
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.098 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0685 0.2809
Brugia malayi hypothetical protein 0.002 0.013 0.0173
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0049 0.004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1208 0.1732
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.001 0.0017
Schistosoma mansoni sugar transporter 0.0014 0.0049 0.0203
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.001 0.0024
Schistosoma mansoni inositol monophosphatase 0.0079 0.0997 0.4086
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0109 0.1429 0.2051
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0182 0.025
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.1576 0.2264
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0119 0.1576 0.9374
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.098 0.1671
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.1341 0.3283
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0049 0.0068
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Plasmodium vivax hypothetical protein, conserved 0.0109 0.1429 0.2298
Schistosoma mansoni protein kinase 0.0032 0.0298 0.1223
Echinococcus multilocularis solute carrier family 22 0.0014 0.0049 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1208 0.4952
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0013 0.0032 0.0077
Mycobacterium ulcerans hypothetical protein 0.0109 0.1429 0.2444
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0064 0.0325
Loa Loa (eye worm) hypothetical protein 0.0084 0.1069 0.1543
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0364 0.058
Plasmodium vivax methionine aminopeptidase 1a, putative 0.0028 0.0241 0.0387
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0606 0.0974
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0364 0.2118
Leishmania major methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0044 0.0474 0.2776
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Mycobacterium leprae Probable lipase LipE 0.0109 0.1429 1
Brugia malayi Inositol-1 0.0079 0.0997 0.1427
Brugia malayi jmjC domain containing protein 0.0015 0.0064 0.0079
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0231 0.0372
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0376 0.5332 0.9168
Loa Loa (eye worm) hypothetical protein 0.002 0.013 0.0187
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.098 0.4016
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0049 0.0237
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0049 0.0057
Schistosoma mansoni inositol monophosphatase 0.0079 0.0997 0.4086
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0156 0.0211
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0064 0.0079
Brugia malayi jmjC domain containing protein 0.0015 0.0064 0.0079
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0064 0.0098
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0044 0.0474 0.2776
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0078 0.098 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.098 0.1671
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0049 0.0071
Schistosoma mansoni carbonyl reductase 0.0012 0.001 0.004
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0289 0.0404
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0064 0.0093
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Giardia lamblia DNA repair protein RAD52 0.0376 0.5332 0.9167
Entamoeba histolytica hypothetical protein 0.0023 0.0174 0.0299
Schistosoma mansoni hypothetical protein 0.0024 0.0182 0.0748
Loa Loa (eye worm) RecQ helicase 0.0022 0.0156 0.0225
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.098 0.9826
Loa Loa (eye worm) hypothetical protein 0.0109 0.1429 0.2062
Echinococcus granulosus solute carrier family 22 0.0014 0.0049 0.0057
Brugia malayi jmjC domain containing protein 0.0058 0.0685 0.0977
Schistosoma mansoni rab6-interacting 0.002 0.013 0.0531
Echinococcus multilocularis solute carrier family 22 0.0014 0.0049 0.0057
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.001 0.001
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0174 0.0425
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Schistosoma mansoni DNA helicase recq5 0.0022 0.0156 0.0638
Loa Loa (eye worm) dehydrogenase 0.0012 0.001 0.0014
Mycobacterium ulcerans esterase/lipase LipP 0.0109 0.1429 0.2444
Schistosoma mansoni protein kinase 0.0032 0.0298 0.1223
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.1208 0.1732
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0049 0.0068
Trypanosoma brucei methionine aminopeptidase, putative 0.0044 0.0474 0.2776
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0298 0.0417
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Toxoplasma gondii oxidoreductase, putative 0.0012 0.001 0.0024
Schistosoma mansoni sugar transporter 0.0014 0.0049 0.0203
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1208 0.1732
Echinococcus granulosus solute carrier family 22 0.0014 0.0049 0.0057
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0685 0.0977
Onchocerca volvulus Huntingtin homolog 0.0123 0.1633 0.2795
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0049 0.0068
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0606 0.1483
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0079 0.0997 0.1714
Brugia malayi Sugar transporter family protein 0.0014 0.0049 0.0057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1208 0.1732
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.098 0.1402
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0156 0.0251
Schistosoma mansoni glucose transport protein 0.0103 0.1341 0.5497
Echinococcus multilocularis chromodomain helicase DNA binding protein 7 0.0013 0.0022 0.0017
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0156 0.0211
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0606 0.3566
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Leishmania major hypothetical protein, conserved 0.0126 0.1681 1
Mycobacterium tuberculosis Conserved protein 0.0109 0.1429 0.142
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0049 0.0057
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.001 0.0014
Schistosoma mansoni intermediate filament proteins 0.0028 0.024 0.0984
Leishmania major hypothetical protein, conserved 0.0016 0.0071 0.0366
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0304 0.1762
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0304 0.0507
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1208 0.1732
Schistosoma mansoni sugar transporter 0.0014 0.0049 0.0203
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Echinococcus granulosus solute carrier family 22 0.0014 0.0049 0.0057
Mycobacterium tuberculosis Methionine aminopeptidase MapB (map) (peptidase M) 0.0028 0.0241 0.0231
Echinococcus granulosus phd:f box containing protein 0.0015 0.0064 0.0079
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0032 0.0032
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0289 0.0481
Echinococcus multilocularis Chromo domain 0.0013 0.0022 0.0018
Schistosoma mansoni helicase 0.0073 0.09 0.3687
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0107 0.1405 0.2028
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0298 0.0417
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.027 0.0376
Echinococcus multilocularis RUN 0.002 0.013 0.0173
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0685 0.0977
Loa Loa (eye worm) BRM protein 0.0038 0.0387 0.0559
Entamoeba histolytica protein kinase, putative 0.0032 0.0298 0.0513
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0012 0.001 0.0024
Schistosoma mansoni rab6-interacting 0.002 0.013 0.0531
Echinococcus multilocularis geminin 0.0178 0.244 0.3513
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0064 0.0263
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0997 0.5908
Schistosoma mansoni steroid dehydrogenase 0.0012 0.001 0.004
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0997 0.5908
Echinococcus multilocularis global transcription activator snf2l2 0.0073 0.09 0.1286
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Giardia lamblia Hexose transporter 0.0014 0.0049 0.0068
Schistosoma mansoni lamin 0.0028 0.024 0.0984
Mycobacterium tuberculosis Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) 0.0028 0.0241 0.0231
Trypanosoma brucei sugar transporter, putative 0.0014 0.0049 0.0237
Brugia malayi Probable ClpP-like protease 0.0078 0.098 0.1402
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0298 0.0431
Schistosoma mansoni glucose transport protein 0.0103 0.1341 0.5497
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0156 0.0211
Loa Loa (eye worm) hypothetical protein 0.0109 0.1429 0.2062
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0071 0.0876 0.0867
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0156 0.0211
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.1341 0.1924
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.001 0.0017
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.001 0.0017
Plasmodium falciparum LCCL domain-containing protein 0.002 0.013 0.0203
Plasmodium falciparum methionine aminopeptidase 1a, putative 0.0028 0.0241 0.0382
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0079 0.0997 0.5908
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Schistosoma mansoni lipoxygenase 0.002 0.013 0.0531
Schistosoma mansoni hypothetical protein 0.0081 0.1017 0.4169
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0049 0.0237
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0304 0.1762
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.001 0.004
Echinococcus granulosus geminin 0.0178 0.244 0.3513
Schistosoma mansoni DNA helicase recq1 0.0022 0.0156 0.0638
Trichomonas vaginalis lymphoid specific helicase, putative 0.0013 0.0032 0.0037
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0289 0.1185
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0156 0.0225
Loa Loa (eye worm) hypothetical protein 0.0023 0.0174 0.0251
Loa Loa (eye worm) intermediate filament protein 0.0028 0.024 0.0347
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0012 0.001 0.0017
Echinococcus multilocularis BRK domain containing protein 0.0013 0.0022 0.0017
Onchocerca volvulus 0.002 0.013 0.0206
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.1429 0.2444
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.001 0.0017
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0156 0.0251
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0156 0.0211
Loa Loa (eye worm) beta-lactamase 0.0109 0.1429 0.2062
Schistosoma mansoni protein kinase 0.0032 0.0298 0.1223
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0064 0.0157
Entamoeba histolytica protein kinase, putative 0.0032 0.0298 0.0513
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0299 0.0475
Trypanosoma brucei methionine aminopeptidase, type I, putative 0.0044 0.0474 0.2776
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0364 0.2118
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0289 0.1185
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0064 0.0093
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0119 0.1576 0.2264
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.001 0.0017
Echinococcus granulosus beta LACTamase domain containing family member 0.0109 0.1429 0.2051
Schistosoma mansoni short chain dehydrogenase 0.0012 0.001 0.004
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Brugia malayi jmjC domain containing protein 0.0015 0.0064 0.0079
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.1341 0.2293
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0156 0.0873
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0119 0.1576 0.646
Loa Loa (eye worm) hypothetical protein 0.0174 0.2385 0.3444
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.1284 0.1842
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0109 0.1429 0.2062
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Plasmodium falciparum mitogen-activated protein kinase 2 0.0166 0.2267 0.3642
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.1341 0.1924
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0586 0.4064
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0304 0.1762
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.013 0.0208
Loa Loa (eye worm) hypothetical protein 0.0031 0.0289 0.0417
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0079 0.0997 0.2441
Schistosoma mansoni loxhd1 0.002 0.013 0.0531
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0685 0.2809
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0364 0.2118
Loa Loa (eye worm) hypothetical protein 0.0015 0.0064 0.0093
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.098 0.2399
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.013 0.0173
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0123 0.0113
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0364 0.2118
Wolbachia endosymbiont of Brugia malayi methionine aminopeptidase 0.0028 0.0241 0.2341
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0064 0.0325
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0156 0.0251
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0049 0.0068
Loa Loa (eye worm) hypothetical protein 0.0025 0.0204 0.0295
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0304 0.0507
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.001 0.0024
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0364 0.2118
Loa Loa (eye worm) hypothetical protein 0.0255 0.3565 0.5146
Mycobacterium tuberculosis Probable lipase LipD 0.0109 0.1429 0.142
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0071 0.0366
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.1208 0.1744
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0093 0.0498
Loa Loa (eye worm) helicase DNA-binding protein 0.0013 0.0022 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0012 0.001 0.0016
Leishmania major hypothetical protein, conserved 0.0109 0.1429 0.8492
Brugia malayi hypothetical protein 0.0034 0.0334 0.0468
Loa Loa (eye worm) hypothetical protein 0.0014 0.0049 0.0071
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.1017 0.1456
Brugia malayi beta-lactamase family protein 0.0109 0.1429 0.2051
Toxoplasma gondii methionine aminopeptidase, type i, putative 0.0028 0.0241 0.059
Loa Loa (eye worm) oxidoreductase 0.0012 0.001 0.0014
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0606 0.3566
Trypanosoma brucei glucose transporter, putative 0.0032 0.0304 0.1762
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0046
Brugia malayi Cam kinase protein 1 0.0032 0.0298 0.0417
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0012 0.001 0.0024
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.1017 0.1456
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Loa Loa (eye worm) doublecortin family protein 0.002 0.013 0.0187
Loa Loa (eye worm) hypothetical protein 0.0123 0.1633 0.2357
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0299 0.0475
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0053 0.0077
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0084 0.1069 0.1838
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0049 0.0074
Trypanosoma brucei glucose transporter 2A 0.0032 0.0304 0.1762
Schistosoma mansoni hypothetical protein 0.0081 0.1017 0.4169
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0119 0.1576 0.1568
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0064 0.0079
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0012 0.001 0.0024
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0156 0.0245
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0071 0.0366
Schistosoma mansoni hypothetical protein 0.0081 0.1017 0.4169
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0299 0.0731
Loa Loa (eye worm) hypothetical protein 0.0013 0.0025 0.0036
Plasmodium vivax DEAD/DEAH helicase, putative 0.0011 0.0003 0.0006
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0156 0.0211
Brugia malayi hypothetical protein 0.0014 0.0049 0.0057
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.013 0.0173
Echinococcus granulosus lamin 0.0028 0.024 0.0333
Echinococcus multilocularis musashi 0.0028 0.024 0.0333
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1208 0.4952
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0409 0.5816 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Entamoeba histolytica hypothetical protein 0.0012 0.001 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0049 0.0068
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) 0.0028 0.0241 0.1628
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0174 0.0282
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0586 0.0577
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0299 0.048
Schistosoma mansoni carbonyl reductase 0.0012 0.001 0.004
Schistosoma mansoni hypothetical protein 0.002 0.013 0.0531
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0049 0.0068
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.098 0.2399
Echinococcus multilocularis GPCR, family 2 0.0081 0.1017 0.1456
Mycobacterium ulcerans methionine aminopeptidase MapB 0.0028 0.0241 0.0398
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0304 0.0507
Schistosoma mansoni hypothetical protein 0.0013 0.0022 0.009
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0298 0.1727
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0174 0.098
Echinococcus granulosus lamin dm0 0.0028 0.024 0.0333
Trypanosoma cruzi hypothetical protein, conserved 0.0126 0.1681 1
Leishmania major glucose transporter, lmgt3 0.0032 0.0304 0.1762
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0049 0.0237
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.001 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0049 0.0068
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0364 0.0891
Loa Loa (eye worm) dehydrogenase 0.0012 0.001 0.0014
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0409 0.5816 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0049 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0049 0.0068
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0685 0.0977
Entamoeba histolytica hypothetical protein 0.0107 0.1401 0.2409
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0685 0.0977
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0064 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0049 0.0068
Echinococcus granulosus General substrate transporter 0.0088 0.113 0.1619

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.