Detailed information for compound 1357722

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 519.772 | Formula: C23H20BrClN2O5
  • H donors: 0 H acceptors: 3 LogP: 3.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOC(=O)[C@@H]1[C@H]2COc3c([C@H]2N2[C@@]1(C)C(=O)N(C2=O)c1ccc(cc1)Cl)cc(cc3)Br
  • InChi: 1S/C23H20BrClN2O5/c1-3-31-20(28)18-16-11-32-17-9-4-12(24)10-15(17)19(16)27-22(30)26(21(29)23(18,27)2)14-7-5-13(25)6-8-14/h4-10,16,18-19H,3,11H2,1-2H3/t16-,18+,19-,23-/m1/s1
  • InChiKey: IKKDKEBIRMANSH-YCMMZOLNSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens snurportin 1 No references
Homo sapiens RAN, member RAS oncogene family No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens multiple endocrine neoplasia I No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0005 0.0009
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0132 0.0209
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0001 0.0014
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0181 0.8753
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0181 0.1331
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0198 0.0738
Plasmodium falciparum glutathione reductase 0.0048 0.0061 0.0695
Echinococcus multilocularis cathepsin L cysteine protease 0.0466 0.088 0.1391
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.007 0.0259
Plasmodium vivax glutathione reductase, putative 0.0048 0.0061 0.0695
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0426 0.0426
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0118 0.0198 0.2256
Brugia malayi hypothetical protein 0.0036 0.0039 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0029 0.0029
Brugia malayi Cathepsin L-like precursor 0.0325 0.0604 0.0604
Echinococcus granulosus intermediate filament protein 0.0055 0.0074 0.0275
Echinococcus multilocularis cpg binding protein 0.0037 0.0039 0.0062
Brugia malayi hypothetical protein 0.0052 0.007 0.007
Entamoeba histolytica cysteine protease, putative 0.0466 0.088 0.903
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1052 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.0475 0.4427
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0305 0.0482
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0112 0.0186 0.0186
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0679 0.64
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0029 0.0029
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0039 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0198 0.1762
Echinococcus multilocularis cathepsin b 0.1391 0.2691 0.4254
Loa Loa (eye worm) hypothetical protein 0.0055 0.0075 0.0075
Brugia malayi Inositol-1 0.0074 0.0112 0.0112
Echinococcus multilocularis lamin dm0 0.0055 0.0074 0.0117
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0198 0.0738
Loa Loa (eye worm) hypothetical protein 0.0141 0.0243 0.0243
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.007 0.0259
Plasmodium vivax hypothetical protein, conserved 0.0022 0.001 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.088 0.3269
Brugia malayi PHD-finger family protein 0.0022 0.001 0.001
Echinococcus multilocularis cathepsin L 0.0118 0.0198 0.0314
Schistosoma mansoni polycystin 1-related 0.0021 0.0009 0.0034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0198 0.0738
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0695 0.0695
Entamoeba histolytica cysteine proteinase, putative 0.0466 0.088 0.903
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0042 0.0154
Schistosoma mansoni hypothetical protein 0.006 0.0086 0.0318
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0042 0.0154
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0086 0.0135
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0029 0.0047
Brugia malayi Cathepsin L-like precursor 0.0466 0.088 0.088
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0029 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.062 0.2305
Loa Loa (eye worm) hypothetical protein 0.0141 0.0243 0.0243
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0042 0.0435
Onchocerca volvulus Alhambra homolog 0.006 0.0086 0.0077
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0554 0.1052 0.1052
Schistosoma mansoni alpha-glucosidase 0.0149 0.0258 0.0959
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0029 0.0029
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0112 0.0417
Echinococcus multilocularis cathepsin L 0.0259 0.0475 0.075
Onchocerca volvulus Cathepsin L homolog 0.0466 0.088 0.0872
Plasmodium vivax vivapain-2 0.0466 0.088 1
Trypanosoma cruzi cruzipain precursor, putative 0.0466 0.088 0.3269
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0466 0.088 0.8336
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0207 0.2136
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Mycobacterium tuberculosis Conserved protein 0.0112 0.0186 0.1362
Brugia malayi Cathepsin L-like precursor 0.0466 0.088 0.088
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2691 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.0186 0.0186
Brugia malayi PHD-finger family protein 0.006 0.0086 0.0086
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.0186 0.1362
Giardia lamblia Cathepsin B precursor 0.0512 0.0969 1
Plasmodium falciparum serine repeat antigen 7 0.0118 0.0198 0.2256
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0029 0.0109
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0105 0.0391
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0554 0.1052 0.1052
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0118 0.0198 0.0198
Brugia malayi Cathepsin L-like precursor 0.0466 0.088 0.088
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0466 0.088 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0097 0.0711
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0028 0.0044
Brugia malayi cathepsin L-like precursor 0.0325 0.0604 0.0604
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0014 0.0141
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0001 0.0005
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0009 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0042 0.0254
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0029 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0016 0.0059
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0033 0.017
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0174 0.0647
Loa Loa (eye worm) hypothetical protein 0.0034 0.0033 0.0033
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.0186 0.1362
Trichomonas vaginalis glucosylceramidase, putative 0.0383 0.0717 0.677
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0105 0.0391
Brugia malayi Doublecortin family protein 0.0021 0.0009 0.0009
Brugia malayi ecdysteroid receptor 0.0032 0.0029 0.0029
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0029 0.0109
Brugia malayi cathepsin F-like cysteine proteinase 0.0118 0.0198 0.0198
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0141 0.0243 0.0243
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0033 0.0124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0305 0.0482
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0198 0.1762
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0042 0.0042
Onchocerca volvulus 0.0241 0.0439 0.043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Schistosoma mansoni cpg binding protein 0.0037 0.0039 0.0145
Echinococcus granulosus cathepsin b 0.1391 0.2691 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0023 0.0064
Echinococcus multilocularis peregrin 0.006 0.0086 0.0135
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.088 0.3269
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0029 0.0109
Plasmodium vivax unspecified product 0.0259 0.0475 0.5396
Plasmodium falciparum serine repeat antigen 4 0.0118 0.0198 0.2256
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0001 0.0001
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0118 0.0198 0.2256
Schistosoma mansoni jumonji domain containing protein 0.002 0.0005 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0466 0.088 0.8336
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.0186 0.1362
Brugia malayi Cathepsin L-like precursor 0.0466 0.088 0.088
Echinococcus granulosus lamin 0.0055 0.0074 0.0275
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0086 0.0086
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0042 0.0157
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0679 0.64
Plasmodium vivax vivapain-3 0.0259 0.0475 0.5396
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0186 0.069
Brugia malayi jmjC domain containing protein 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0084 0.0132 0.0132
Echinococcus granulosus cathepsin L 0.0118 0.0198 0.0738
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0118 0.0198 0.0738
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0029 0.0109
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0113 0.0422
Loa Loa (eye worm) hypothetical protein 0.0325 0.0604 0.0604
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0029 0.0109
Onchocerca volvulus Glucosylceramidase homolog 0.0364 0.0679 0.0671
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0118 0.0198 0.1762
Mycobacterium leprae conserved hypothetical protein 0.0112 0.0186 0.8976
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0061 0.0448
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0019
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0106 0.0174 0.0275
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0112 0.1156
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0022
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0023 0.0084
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0009 0.0014
Trypanosoma brucei glucosidase, putative 0.0038 0.0042 0.0435
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0042 0.0154
Loa Loa (eye worm) hypothetical protein 0.0118 0.0198 0.0198
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0009 0.0014
Leishmania major GTP-binding protein, putative 0.0026 0.0017 0.018
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0044 1
Plasmodium vivax vivapain-2 0.0466 0.088 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0044 0.0044
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.0017
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0016 0.0059
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0117 0.0117
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0009 0.0035
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0035 0.0035
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0013 0.0049
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0475 0.1764
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0112 0.0177
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0005 0.002
Plasmodium vivax hypothetical protein, conserved 0.006 0.0086 0.0973
Brugia malayi fibroinase precursor 0.0118 0.0198 0.0198
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.0475 0.0475
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.0186 0.1362
Onchocerca volvulus 0.0466 0.088 0.0872
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0466 0.088 0.088
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0005 0.002
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0132 0.0209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0112 0.0928
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0033 0.0033
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0044 0.0165
Loa Loa (eye worm) fibroinase 0.0466 0.088 0.088
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0005 0.0056
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0017 0.0065
Giardia lamblia Cathepsin L precursor 0.0118 0.0198 0.2038
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0112 1
Onchocerca volvulus 0.0325 0.0604 0.0595
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0029 0.0029
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0198 0.2038
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0017 0.0028
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0132 0.049
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0044 0.0044
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0475 0.1764
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0029 0.0047
Schistosoma mansoni cathepsin F (C01 family) 0.0466 0.088 0.3269
Brugia malayi intermediate filament protein 0.0055 0.0074 0.0074
Echinococcus multilocularis cathepsin L cysteine protease 0.0466 0.088 0.1391
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0044 0.0446
Loa Loa (eye worm) ctsf protein 0.0466 0.088 0.088
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0033 0.017
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0029 0.0029
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0118 0.0198 0.2256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Echinococcus granulosus pyruvate kinase 0.0034 0.0033 0.0124
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.0186 0.8893
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Mycobacterium ulcerans hypothetical protein 0.0025 0.0016 0.0114
Trypanosoma brucei trypanothione reductase 0.0048 0.0061 0.063
Schistosoma mansoni cathepsin C 0.0118 0.0198 0.0738
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0029 0.0029
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0118 0.0198 0.2256
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.039 0.1448
Trypanosoma cruzi cruzipain precursor, putative 0.0141 0.0243 0.0905
Onchocerca volvulus 0.0466 0.088 0.0872
Giardia lamblia Cathepsin L precursor 0.0118 0.0198 0.2038
Brugia malayi hypothetical protein 0.0147 0.0255 0.0255
Echinococcus granulosus cathepsin L cysteine proteinase 0.0466 0.088 0.3269
Loa Loa (eye worm) hypothetical protein 0.006 0.0086 0.0086
Onchocerca volvulus 0.0035 0.0035 0.0026
Trypanosoma cruzi cysteine peptidase, putative 0.0141 0.0243 0.0905
Onchocerca volvulus 0.0084 0.0132 0.0123
Giardia lamblia Cathepsin B precursor 0.0512 0.0969 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0009 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.0475 0.4427
Plasmodium vivax unspecified product 0.0118 0.0198 0.2256
Schistosoma mansoni inositol monophosphatase 0.0074 0.0112 0.0417
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0016 0.0025
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0042 0.0157
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0002
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0005 0.002
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0086 0.0318
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0005 0.002
Trypanosoma cruzi cysteine proteinase, putative 0.0259 0.0475 0.1764
Plasmodium falciparum serine repeat antigen 5 0.0118 0.0198 0.2256
Loa Loa (eye worm) RNA binding protein 0.0076 0.0117 0.0117
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0198 0.1762
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0016 0.0116
Schistosoma mansoni intermediate filament proteins 0.0055 0.0074 0.0275
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0198 0.0738
Brugia malayi Cathepsin L-like precursor 0.0466 0.088 0.088
Schistosoma mansoni hypothetical protein 0.0372 0.0695 0.2583
Entamoeba histolytica hypothetical protein 0.0036 0.0039 0.0262
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.0186 0.0186
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0186 0.1638
Schistosoma mansoni cpg binding protein 0.0035 0.0035 0.0131
Echinococcus granulosus cysteine protease 0.0259 0.0475 0.1764
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0198 0.1762
Entamoeba histolytica hypothetical protein 0.0118 0.0198 0.1929
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0028 0.0104
Onchocerca volvulus Cathepsin L homolog 0.0466 0.088 0.0872
Brugia malayi beta-lactamase family protein 0.0112 0.0186 0.0186
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0029 0.0047
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0086 0.0883
Brugia malayi cathepsin L precursor 0.0118 0.0198 0.0198
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0042 0.0254
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0041
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1391 0.2691 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0029 0.0109
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0118 0.0198 0.2256
Schistosoma mansoni loxhd1 0.0021 0.0009 0.0034
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0118 0.0198 0.2256
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0128 0.0217 0.0807
Brugia malayi Bromodomain containing protein 0.006 0.0086 0.0086
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0029 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0198 0.1762
Plasmodium falciparum phd finger protein, putative 0.006 0.0086 0.0973
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0029 0.0029
Echinococcus granulosus lamin dm0 0.0055 0.0074 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0186 0.069
Echinococcus multilocularis phd:f box containing protein 0.002 0.0005 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0259 0.0475 0.4897
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.001 0.0114
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0044 0.0165
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0118 0.0198 0.2256
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0035 0.0365
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.062 0.2305
Echinococcus multilocularis GPCR, family 2 0.0017 0.0001 0.0002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0024 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.062 0.2305
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0033 0.0033
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0198 0.0198
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0207 0.0769
Schistosoma mansoni hypothetical protein 0.0023 0.0013 0.0049
Mycobacterium ulcerans lipase LipD 0.0112 0.0186 0.8893
Giardia lamblia Cysteine protease 0.0118 0.0198 0.2038
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0186 0.1638
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0198 0.1762
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.0186 0.1362
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0044 0.0165
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.088 0.3269
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0186 0.069
Giardia lamblia Encystation-specific protease 0.0118 0.0198 0.2038
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0514 0.0973 1
Brugia malayi nuclear receptor NHR-88 0.0032 0.0029 0.0029
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0017 0.0198
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0029 0.0109
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0029 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.0466 0.088 0.903
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Giardia lamblia Cathepsin B precursor 0.0118 0.0198 0.2038
Loa Loa (eye worm) hypothetical protein 0.1391 0.2691 0.2691
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0475 0.4808
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0029 0.0109
Toxoplasma gondii ABC1 family protein 0.0112 0.0186 0.1915
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0112 0.1028
Loa Loa (eye worm) beta-lactamase 0.0112 0.0186 0.0186
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0198 0.1929
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.007 0.0791
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0475 0.4808
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0117 0.0185
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0029 0.0109
Schistosoma mansoni hypothetical protein 0.0036 0.0039 0.0143
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0028 0.0104
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0207 0.0769
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0934 0.1477
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.007 0.0791
Plasmodium falciparum serine repeat antigen 2 0.0118 0.0198 0.2256
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0117 0.0435
Onchocerca volvulus 0.0112 0.0186 0.0177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0325 0.0604 0.5671
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0028 0.0044
Giardia lamblia PHD finger protein 15 0.006 0.0086 0.0871
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0325 0.0604 0.2243
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0028 0.0104
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.0186 0.8893
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0005 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Brugia malayi hypothetical protein 0.0126 0.0213 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0028 0.0104
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0002
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0042 0.0067
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0198 0.1762
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0112 0.0417
Schistosoma mansoni cathepsin S (C01 family) 0.0118 0.0198 0.0738
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0041 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Brugia malayi Importin beta-1 subunit 0.0035 0.0035 0.0035
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0259 0.0475 0.1764
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0466 0.088 0.1391
Loa Loa (eye worm) hypothetical protein 0.0104 0.017 0.017
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1052 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0198 0.1762
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0174 0.0647
Schistosoma mansoni hypothetical protein 0.0494 0.0934 0.3473
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0039 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0118 0.0198 0.1762
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0118 0.0198 0.0198
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0014 0.0141
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0033 0.038
Brugia malayi hypothetical protein 0.0034 0.0033 0.0033
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0014 0.01
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1391 0.2691 1
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0061 0.0695
Schistosoma mansoni lamin 0.0055 0.0074 0.0275
Mycobacterium tuberculosis Conserved protein 0.0112 0.0186 0.1362
Loa Loa (eye worm) hypothetical protein 0.0126 0.0213 0.0213
Echinococcus granulosus snurportin 1 0.0372 0.0695 0.2583
Loa Loa (eye worm) hypothetical protein 0.0514 0.0973 0.0973
Plasmodium falciparum cysteine proteinase falcipain 1 0.0259 0.0475 0.5396
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0033 0.0033
Mycobacterium tuberculosis Probable reductase 0.0109 0.0181 0.1331
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0426 0.0426
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Brugia malayi hypothetical protein 0.0021 0.0009 0.0009
Onchocerca volvulus 0.0032 0.0029 0.002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0713 0.1363 1
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0106 0.0174 0.0275
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0186 0.1638
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0042 0.0042
Mycobacterium ulcerans hypothetical protein 0.0025 0.0016 0.0114
Giardia lamblia Cysteine protease 0.0118 0.0198 0.2038
Schistosoma mansoni phd/f-box containing protein 0.002 0.0005 0.002
Echinococcus multilocularis RUN 0.0021 0.0009 0.0014
Plasmodium vivax SET domain protein, putative 0.0031 0.0028 0.0318
Brugia malayi Papain family cysteine protease containing protein 0.0466 0.088 0.088
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0033 0.1024
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0024 0.009
Trypanosoma brucei cysteine peptidase C (CPC) 0.0512 0.0969 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Mycobacterium tuberculosis Conserved protein 0.0112 0.0186 0.1362
Giardia lamblia Cathepsin L-like protease 0.0118 0.0198 0.2038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0042
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0117 0.0117
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0001 0.0001
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0132 0.0492
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0141 0.0243 0.0243
Onchocerca volvulus Cathepsin L homolog 0.0118 0.0198 0.019
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0118 0.0198 0.0738
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0112 0.509
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0016 0.0114
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0042 0.0247
Onchocerca volvulus 0.0466 0.088 0.0872
Brugia malayi Pre-SET motif family protein 0.0212 0.0382 0.0382
Plasmodium vivax vivapain-1 0.0259 0.0475 0.5396
Loa Loa (eye worm) hypothetical protein 0.0466 0.088 0.088
Schistosoma mansoni pyruvate kinase 0.0034 0.0033 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0042 0.0247
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0029 0.0029
Onchocerca volvulus 0.0112 0.0186 0.0177
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0033 0.0345
Brugia malayi jmjC domain containing protein 0.002 0.0005 0.0005
Echinococcus granulosus cathepsin l1 0.0325 0.0604 0.2243
Entamoeba histolytica Ran family GTPase 0.0026 0.0017 0.0042
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0017
Echinococcus granulosus cathepsin L cysteine protease 0.0259 0.0475 0.1764
Echinococcus granulosus RUN 0.0021 0.0009 0.0034
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0014 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0028 0.0289
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0001 0.0013
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.0186 0.069
Brugia malayi AF-10 protein 0.002 0.0006 0.0006
Brugia malayi MH2 domain containing protein 0.0144 0.025 0.025
Brugia malayi jmjC domain containing protein 0.002 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.0039 0.0262
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0006 0.0061
Giardia lamblia Cathepsin B precursor 0.0512 0.0969 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0198 0.0198
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0005 0.0009
Brugia malayi nuclear hormone receptor 0.0032 0.0029 0.0029
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0512 0.0969 0.3602
Onchocerca volvulus 0.0466 0.088 0.0872
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0132 0.0132
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0475 0.1764
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0198 0.0198
Giardia lamblia Hypothetical protein 0.0118 0.0198 0.2038
Brugia malayi cathepsin B-like cysteine proteinase 0.1391 0.2691 0.2691
Giardia lamblia Cathepsin L precursor 0.0118 0.0198 0.2038
Echinococcus granulosus cathepsin l cysteine peptidase 0.0466 0.088 0.3269
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0042 0.0428
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0198 0.0738
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0042 0.0154
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0042 0.03
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0042 0.0254
Loa Loa (eye worm) hypothetical protein 0.0118 0.0198 0.0198
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0061 0.0097
Loa Loa (eye worm) hypothetical protein 0.0112 0.0186 0.0186
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0042 0.0247
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0333 0.062 0.062
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0512 0.0969 0.92
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0029 0.0047
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.007 0.0718
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.0186 0.1362
Schistosoma mansoni rab6-interacting 0.0021 0.0009 0.0034
Echinococcus multilocularis pyruvate kinase 0.0034 0.0033 0.0053
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0118 0.0198 0.2256
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0029 0.0029
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0174 0.0647
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0466 0.088 0.088
Brugia malayi beta-lactamase 0.0112 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0141 0.0243 0.0243
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0029 0.002
Trichomonas vaginalis ran, putative 0.0026 0.0017 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0042 0.0254
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.025 0.025
Entamoeba histolytica cysteine protease, putative 0.0118 0.0198 0.1929
Onchocerca volvulus Huntingtin homolog 0.0126 0.0213 0.0204
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0112 0.0928
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0029 0.0029
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0305 0.1134
Onchocerca volvulus 0.0118 0.0198 0.019
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Entamoeba histolytica cysteine proteinase, putative 0.0325 0.0604 0.6151
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0118 0.0198 0.2256
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0042 0.0254
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.025 0.025
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0042 0.0066
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0056
Brugia malayi Cathepsin L-like precursor 0.0325 0.0604 0.0604
Schistosoma mansoni cathepsin B (C01 family) 0.0118 0.0198 0.0738
Entamoeba histolytica cysteine protease, putative 0.0118 0.0198 0.1929
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0006 0.0061
Schistosoma mansoni hypothetical protein 0.0037 0.0041 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0029 0.0029
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0044 0.007
Echinococcus granulosus cathepsin b 0.1391 0.2691 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0075 0.0075
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0186 0.1638
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0029 0.0109
Echinococcus multilocularis cathepsin b 0.1391 0.2691 0.4254
Schistosoma mansoni jumonji domain containing protein 0.0157 0.0275 0.1023
Trichomonas vaginalis glucosylceramidase, putative 0.0383 0.0717 0.677
Entamoeba histolytica hypothetical protein 0.0028 0.0023 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0679 0.64
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0198 0.2256
Echinococcus multilocularis cysteine protease 0.0466 0.088 0.1391
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0039 0.0143
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0019 0.003
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0005 0.002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0042 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0198 0.1762
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0016 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Toxoplasma gondii cathepsin CPC2 0.0118 0.0198 0.2048
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0042 0.0066
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0017 0.0065
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0029 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0117 0.0435
Echinococcus granulosus phd:f box containing protein 0.002 0.0005 0.002
Onchocerca volvulus 0.0147 0.0255 0.0246
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0198 0.2038
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0005
Loa Loa (eye worm) glutathione reductase 0.0048 0.0061 0.0061
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0086 0.0883
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0205 0.1506
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0029 0.0109
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0512 0.0969 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0112 0.1156
Loa Loa (eye worm) hypothetical protein 0.0055 0.0074 0.0074
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.062 0.098
Plasmodium falciparum serine repeat antigen 6 0.0118 0.0198 0.2256
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0128 0.0217 0.0343
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0114 0.0425
Chlamydia trachomatis pyruvate kinase 0.0034 0.0033 1
Plasmodium falciparum pyruvate kinase 0.0034 0.0033 0.038
Onchocerca volvulus Cathepsin F homolog 0.0466 0.088 0.0872
Entamoeba histolytica cysteine protease, putative 0.0118 0.0198 0.1929
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0186 0.211
Trichomonas vaginalis set domain proteins, putative 0.0241 0.0439 0.4083
Echinococcus granulosus peregrin 0.006 0.0086 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0198 0.1762
Leishmania major cysteine peptidase A (CPA) 0.0466 0.088 0.9076
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0006 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0118 0.0198 0.1762
Entamoeba histolytica hypothetical protein 0.0024 0.0014 0.0002
Loa Loa (eye worm) hypothetical protein 0.0147 0.0255 0.0255
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0259 0.0475 0.4897
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0466 0.088 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0198 0.0198
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1052 1
Onchocerca volvulus 0.0055 0.0074 0.0065
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0001 0.0001
Echinococcus granulosus GPCR family 2 0.0017 0.0001 0.0005
Brugia malayi RNA, U transporter 1 0.0099 0.0161 0.0161
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0198 0.0738
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0005
Schistosoma mansoni cathepsin F (C01 family) 0.0325 0.0604 0.2243
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0014 0.0141
Schistosoma mansoni coup transcription factor 0.0032 0.0029 0.0109
Trypanosoma cruzi cysteine protease, putative 0.0259 0.0475 0.1764
Loa Loa (eye worm) hypothetical protein 0.0126 0.0213 0.0213
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0114 0.0425
Giardia lamblia Cathepsin B precursor 0.0118 0.0198 0.2038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0512 0.0969 0.3602
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0005
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0016 0.0114
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0001 0.0002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0198 0.0355 0.0561
Echinococcus multilocularis pyruvate kinase 0.0027 0.002 0.0031
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.0198
Schistosoma mansoni pyruvate kinase 0.0017 0.0001 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1052 1
Echinococcus granulosus cpg binding protein 0.0037 0.0039 0.0145
Giardia lamblia Pyruvate kinase 0.0034 0.0033 0.0333
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0679 0.64
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0044 0.0458
Plasmodium falciparum importin beta, putative 0.0035 0.0035 0.0403
Onchocerca volvulus 0.0466 0.088 0.0872
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.007 0.0105 0.0862
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0042 0.0254
Schistosoma mansoni pyruvate kinase 0.0034 0.0033 0.0124
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0019 0.007
Brugia malayi Cathepsin L-like precursor 0.0141 0.0243 0.0243
Plasmodium vivax JmjC domain containing protein 0.002 0.0005 0.0062
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0333 0.062 0.062
Brugia malayi CXXC zinc finger family protein 0.0035 0.0035 0.0035
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.0186 0.1362
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0114 0.0425
Brugia malayi steroid hormone receptor 0.0032 0.0029 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0679 0.64
Loa Loa (eye worm) jmjC domain-containing protein 0.0125 0.0212 0.0212
Entamoeba histolytica cysteine protease, putative 0.0118 0.0198 0.1929
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.007 0.0105 0.0105
Onchocerca volvulus 0.5123 1 1
Entamoeba histolytica cysteine protease, putative 0.0118 0.0198 0.1929
Brugia malayi cathepsin L-like cysteine proteinase 0.0118 0.0198 0.0198
Schistosoma mansoni ap endonuclease 0.0039 0.0044 0.0165
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0001 0.0014
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.0382 0.0382
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0042 0.0293
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0005
Loa Loa (eye worm) IKK protein kinase 0.5123 1 1
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0005 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0259 0.0475 0.1764
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.0186 0.1915
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0035 0.0365
Echinococcus granulosus pyruvate kinase 0.0034 0.0033 0.0124
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0009 0.0015
Schistosoma mansoni cpg binding protein 0.0037 0.0039 0.0145
Brugia malayi cathepsin F-like cysteine proteinase 0.0141 0.0243 0.0243
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.007 0.0791
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.039 0.1448
Echinococcus granulosus importin subunit beta 1 0.0035 0.0035 0.0132
Mycobacterium leprae Probable lipase LipE 0.0112 0.0186 0.8976
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Onchocerca volvulus 0.0466 0.088 0.0872
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0033 0.0033
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0205 0.1506
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0198 0.1929
Leishmania major pyruvate kinase 0.0034 0.0033 0.0345
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0181 0.1331
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0098 0.1012
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0016 0.0164
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0005 0.0056
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0042 0.0154
Echinococcus granulosus tar DNA binding protein 0.0076 0.0117 0.0435
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2691 1
Toxoplasma gondii cathepsin B 0.0512 0.0969 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Loa Loa (eye worm) hypothetical protein 0.0325 0.0604 0.0604
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0207 1
Brugia malayi Thioredoxin reductase 0.0048 0.0061 0.0061
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0198 0.0355 0.1319
Brugia malayi jmjC domain containing protein 0.0198 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0023 0.0064
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0033 0.0345
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0207 1
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0934 0.3473
Entamoeba histolytica cysteine proteinase 1, putative 0.0259 0.0475 0.4808
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0029 0.0029
Brugia malayi Cathepsin L-like precursor 0.0466 0.088 0.088
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0042 0.0428
Echinococcus granulosus cathepsin l1 0.0466 0.088 0.3269
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0033 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Toxoplasma gondii cathepsin CPL 0.0466 0.088 0.9076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Mycobacterium ulcerans hypothetical protein 0.0112 0.0186 0.8893
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0024 0.0024
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0017 0.0065
Plasmodium falciparum thioredoxin reductase 0.0048 0.0061 0.0695
Brugia malayi RNA binding protein 0.0076 0.0117 0.0117
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0005 0.002
Giardia lamblia Hypothetical protein 0.0118 0.0198 0.2038
Plasmodium falciparum serine repeat antigen 9 0.0118 0.0198 0.2256
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Brugia malayi Melibiase family protein 0.007 0.0105 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0052 0.007 0.007
Toxoplasma gondii cathepsin CPC1 0.0118 0.0198 0.2048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0207 1
Echinococcus multilocularis musashi 0.0055 0.0074 0.0117
Trypanosoma brucei hypothetical protein, conserved 0.0216 0.039 0.4019
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0198 0.2038
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0174 0.0647
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0118 0.0198 0.2256
Schistosoma mansoni lipoxygenase 0.0128 0.0217 0.0807
Trichomonas vaginalis esterase, putative 0.0112 0.0186 0.1638
Echinococcus granulosus cathepsin L 0.0259 0.0475 0.1764
Brugia malayi Pre-SET motif family protein 0.0031 0.0028 0.0028
Schistosoma mansoni importin beta-1 0.0035 0.0035 0.0132
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0029 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0205 0.1506
Plasmodium falciparum serine repeat antigen 1 0.0118 0.0198 0.2256
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0033 0.0033
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0029 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0207 0.2136
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0117 0.0435
Onchocerca volvulus Huntingtin homolog 0.0126 0.0213 0.0204
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.0039 0.0262
Echinococcus multilocularis cysteine protease 0.0466 0.088 0.1391
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0118 0.0198 0.1762
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0029 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0198 0.1762
Onchocerca volvulus 0.0112 0.0186 0.0177
Leishmania major hypothetical protein, conserved 0.0052 0.007 0.0718
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0028 0.0104
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0025 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Schistosoma mansoni rab6-interacting 0.0021 0.0009 0.0034
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0042 0.0154
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0034
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0033 0.0345
Brugia malayi jmjC domain containing protein 0.002 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0118 0.0198 0.1929
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0009 0.0034
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0061 0.0227
Loa Loa (eye worm) hypothetical protein 0.0112 0.0186 0.0186
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0005 0.0062
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.062 0.098
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0023 0.0064
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0042 0.0254
Giardia lamblia Cathepsin L precursor 0.0118 0.0198 0.2038
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0042 0.0154
Giardia lamblia Cathepsin L precursor 0.0118 0.0198 0.2038
Loa Loa (eye worm) hypothetical protein 0.0112 0.0186 0.0186
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0075 0.0075
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0005 0.002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0029 0.0029
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0029 0.0029
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0002
Schistosoma mansoni alpha glucosidase 0.0038 0.0042 0.0157
Mycobacterium ulcerans beta-lactamase 0.0112 0.0186 0.8893
Loa Loa (eye worm) cathepsin B 0.0512 0.0969 0.0969
Loa Loa (eye worm) hypothetical protein 0.0031 0.0028 0.0028
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.011 0.0175
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0097 0.4345
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0044 0.0323
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0017 0.018
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0033 0.0124
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0061 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.0186 0.0186
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0044 0.0276
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0074 0.0074
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0198 0.0738
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0118 0.0198 0.2038
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0198 0.2256
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0009 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0679 0.64
Onchocerca volvulus 0.0055 0.0074 0.0065
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0198 0.2256
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0198 0.2256
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0029 0.0029
Leishmania major hypothetical protein, conserved 0.0216 0.039 0.4019
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.0167
Giardia lamblia Cathepsin L precursor 0.0118 0.0198 0.2038
Onchocerca volvulus 0.0031 0.0028 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1052 1
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0198 0.1762
Leishmania major trypanothione reductase 0.0048 0.0061 0.063
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0042 0.0435
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.088 0.3269
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0014 0.0141
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Schistosoma mansoni protein phosphatase 2C 0.002 0.0005 0.002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0181 0.1331
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2691 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.088 0.8336
Plasmodium vivax unspecified product 0.0141 0.0243 0.2767
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0207 0.0327
Onchocerca volvulus 0.0466 0.088 0.0872
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0305 0.0305
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Schistosoma mansoni lipoxygenase 0.0089 0.0142 0.0528
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0029 0.0029
Echinococcus multilocularis snurportin 1 0.0372 0.0695 0.1099
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0029 0.0029
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0132 0.0492
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0198 0.1762
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0017
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0029 0.002
Onchocerca volvulus 0.01 0.0163 0.0154
Leishmania major hypothetical protein, conserved 0.0112 0.0186 0.1915
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0475 0.4808
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0207 0.0769
Brugia malayi jmjC domain containing protein 0.0075 0.0114 0.0114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0029 0.0047
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0198 0.0738
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0186 0.1638
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0086 0.0318
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0005 0.0005
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0325 0.0604 0.0604
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0009 0.0014
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0074 0.0074
Entamoeba histolytica cysteine proteinase 2 0.0259 0.0475 0.4808
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.062 0.2305
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0198 0.1762
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0029 0.0047
Loa Loa (eye worm) hypothetical protein 0.0118 0.0198 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0325 0.0604 0.5671
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0029 0.0109
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0044 0.0505
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0044 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0198 0.1762
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0112 0.0928
Toxoplasma gondii melibiase subfamily protein 0.0106 0.0174 0.1796
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0006 0.0061
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0114 0.0114
Echinococcus multilocularis pyruvate kinase 0.0034 0.0033 0.0053
Leishmania major cathepsin L-like protease 0.0466 0.088 0.9076
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0033 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.088 0.9076
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0035 0.0365
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.062 0.2305
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0029 0.0109
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0117 0.0117
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0029 0.0109
Schistosoma mansoni cathepsin F (C01 family) 0.0466 0.088 0.3269
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0207 0.1519
Loa Loa (eye worm) hypothetical protein 0.0118 0.0198 0.0198
Schistosoma mansoni lamin 0.0055 0.0074 0.0275
Loa Loa (eye worm) inositol-1 0.0074 0.0112 0.0112
Schistosoma mansoni inositol monophosphatase 0.0074 0.0112 0.0417
Loa Loa (eye worm) cysteine protease 0.0466 0.088 0.088
Plasmodium falciparum cysteine proteinase falcipain 3 0.0466 0.088 1
Giardia lamblia Cathepsin L-like protease 0.0118 0.0198 0.2038
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0036 0.0039 0.0262
Schistosoma mansoni ran 0.0026 0.0017 0.0065
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0514 0.0973 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0466 0.088 0.1391
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0118 0.0198 0.2256
Brugia malayi glutathione reductase 0.0048 0.0061 0.0061
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0112 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0024 0.0013 0.0013
Schistosoma mansoni ran 0.0026 0.0017 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0029 0.0029
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0016 0.0059
Brugia malayi beta-lactamase family protein 0.0112 0.0186 0.0186
Mycobacterium tuberculosis Conserved protein 0.0025 0.0016 0.0116
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3247 0.6326 1
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0074 0.0074
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0042 0.0254
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0042 0.0066
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0305 0.0305
Plasmodium falciparum serine repeat antigen 8 0.0118 0.0198 0.2256
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0475 0.4808
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0679 0.64
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0042 0.0042
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0181 0.1331
Giardia lamblia Cysteine protease 0.0118 0.0198 0.2038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0029 0.0029
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0035 0.0056
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0017 0.018
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0005 0.0005
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0014 0.0155
Loa Loa (eye worm) hypothetical protein 0.0054 0.0072 0.0072
Giardia lamblia Cathepsin B precursor 0.0118 0.0198 0.2038
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0033 0.1033
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0009 0.0102
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0029 0.0109
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0033 0.0246
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Schistosoma mansoni alpha-glucosidase 0.0149 0.0258 0.0959
Leishmania major pyruvate kinase 0.0034 0.0033 0.0345
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0029 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0117 0.0435
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0075 0.0075
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0029 0.0047
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0198 0.0738
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0044 0.3126
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0205 1
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0005
Entamoeba histolytica cysteine protease, putative 0.0259 0.0475 0.4808
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0042 0.0157
Trypanosoma cruzi cysteine proteinase, putative 0.0259 0.0475 0.1764
Leishmania major importin beta-1 subunit, putative 0.0028 0.0023 0.0232
Schistosoma mansoni ap endonuclease 0.0039 0.0044 0.0165
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.007 0.0718
Brugia malayi Cathepsin L-like cysteine proteinase 0.0325 0.0604 0.0604
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0044 0.1591
Plasmodium falciparum serine repeat antigen 3 0.0118 0.0198 0.2256
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1052 1
Echinococcus multilocularis lamin 0.0055 0.0074 0.0117
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0042 0.0416
Plasmodium vivax importin-beta 2, putative 0.0035 0.0035 0.0403
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0198 0.0198
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0112 0.0417
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0029 0.0047
Brugia malayi TAR-binding protein 0.0076 0.0117 0.0117
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0186 0.069
Brugia malayi hypothetical protein 0.0021 0.0009 0.0009
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0181 0.1331
Giardia lamblia Cathepsin B precursor 0.0118 0.0198 0.2038
Toxoplasma gondii thioredoxin reductase 0.0048 0.0061 0.063
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0198 0.0198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.088 0.8336
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0042 0.0254
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0029 0.0109
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0106 0.0174 0.0647
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0061 0.0061
Giardia lamblia Cathepsin B precursor 0.0118 0.0198 0.2038
Toxoplasma gondii preprocathepsin c precursor, putative 0.0118 0.0198 0.2048
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0044 0.0276
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.0186 0.0293
Giardia lamblia Cysteine protease 0.0118 0.0198 0.2038
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0029 0.0047
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0044 0.0458
Schistosoma mansoni cathepsin s 0.0141 0.0243 0.0905
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0112 0.1156
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0117 0.0435
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0009 0.0102
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0033 0.0024
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0198 0.0198
Toxoplasma gondii exonuclease III APE 0.0039 0.0044 0.0458
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0198 0.0198
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0044 0.0326

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1.4125 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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