Detailed information for compound 1383743

Basic information

Technical information
  • TDR Targets ID: 1383743
  • Name: [(2S,3S,4S)-4-acetyloxy-2-methyl-3,4-dihydro- 2H-pyran-3-yl] acetate
  • MW: 214.215 | Formula: C10H14O5
  • H donors: 0 H acceptors: 2 LogP: 0.65 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)O[C@H]1[C@H](C)OC=C[C@@H]1OC(=O)C
  • InChi: 1S/C10H14O5/c1-6-10(15-8(3)12)9(4-5-13-6)14-7(2)11/h4-6,9-10H,1-3H3/t6-,9-,10-/m0/s1
  • InChiKey: NDEGMKQAZZBNBB-JUWDTYFHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(2S,3S,4S)-4-acetoxy-2-methyl-3,4-dihydro-2H-pyran-3-yl] acetate
  • acetic acid [(2S,3S,4S)-4-acetoxy-2-methyl-3,4-dihydro-2H-pyran-3-yl] ester
  • [(2S,3S,4S)-4-acetyloxy-2-methyl-3,4-dihydro-2H-pyran-3-yl] ethanoate
  • Di-O-acetyl-L-rhamnal
  • STOCK1N-01810
  • ZINC04023511
  • 3,4-Di-O-acetyl-6-deoxy-L-glucal
  • 332291_ALDRICH

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.006 0.006 0.0284
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Echinococcus multilocularis integrin linked protein kinase 0.0042 0.0015 0.001
Echinococcus granulosus protein tyrosine kinase 0.0042 0.0015 0.001
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0093 0.0602
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0042 0.0015 0.001
Entamoeba histolytica hypothetical protein 0.0076 0.01 0.0559
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0076 0.01 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0066 0.006
Echinococcus multilocularis ephrin type A receptor 4 A 0.0042 0.0015 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.006 0.006 0.5267
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.338 0.8364 0.8363
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TK family protein kinase 0.0042 0.0015 0.0095
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0042 0.0015 0.0008
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.006 0.006 0.5267
Trichomonas vaginalis AGC family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) TK/FAK protein kinase 0.0042 0.0015 0.0008
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0654 0.1546 0.1533
Schistosoma mansoni regulator of G protein signaling 0.0654 0.1546 0.1533
Loa Loa (eye worm) hypothetical protein 0.0288 0.0629 0.0623
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Echinococcus multilocularis actin binding protein anillin 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0288 0.0629 0.0623
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Brugia malayi Sema domain containing protein 0.0288 0.0629 0.0623
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0063 0.0066 0.0072
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.006 0.006 0.0064
Brugia malayi PXA domain containing protein 0.0654 0.1546 0.154
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0058 0.0055 0.4733
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.006 0.0295
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0042 0.0015 0.0095
Echinococcus granulosus beta 1 syntrophin 0.006 0.006 0.0064
Entamoeba histolytica protein kinase, putative 0.0076 0.01 0.0559
Schistosoma mansoni fibrocystin l 0.0126 0.0225 0.0211
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0042 0.0015 0.001
Brugia malayi Raf kinase 0.0042 0.0015 0.0008
Echinococcus granulosus pleckstrin y domain containing family A 0.006 0.006 0.0064
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0042 0.0015 0.001
Brugia malayi DNA-binding protein LAG-1 0.0126 0.0225 0.0219
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Brugia malayi Uncoordinated protein 104 0.006 0.006 0.0053
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis epidermal growth factor receptor 0.0042 0.0015 0.001
Echinococcus multilocularis c src tyrosine kinase 0.0042 0.0015 0.001
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.006 0.0295
Trichomonas vaginalis protein kinase atn1, putative 0.0042 0.0015 0.0095
Trypanosoma brucei protein kinase, putative 0.0076 0.01 1
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Onchocerca volvulus 0.006 0.006 0.0284
Plasmodium vivax conserved Plasmodium protein, unknown function 0.006 0.006 0.5267
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0042 0.0015 0.001
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.006 0.006 0.0064
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0042 0.0015 0.001
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Trichomonas vaginalis CAMK family protein kinase 0.0042 0.0015 0.0095
Toxoplasma gondii aurora kinase 0.0073 0.0093 0.9159
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Loa Loa (eye worm) serine/threonine protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.006 0.006 0.0387
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0042 0.0015 0.001
Schistosoma mansoni zinc finger protein 0.006 0.006 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0042 0.0015 0.001
Echinococcus multilocularis Pleckstrin y 0.006 0.006 0.0064
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0042 0.0015 0.001
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.006 0.006 0.5267
Brugia malayi Sema domain containing protein 0.0288 0.0629 0.0623
Trypanosoma cruzi hypothetical protein 0.006 0.006 0.5267
Echinococcus granulosus pdz domain containing protein 0.006 0.006 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Entamoeba histolytica hypothetical protein 0.006 0.006 0.0295
Trichomonas vaginalis protein transport protein sec7, putative 0.006 0.006 0.0387
Trypanosoma cruzi hypothetical protein 0.006 0.006 0.5267
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Echinococcus granulosus fibroblast growth factor receptor 4 0.0042 0.0015 0.001
Loa Loa (eye worm) Plekhf2 protein 0.006 0.006 0.0053
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0042 0.0015 0.001
Loa Loa (eye worm) plexin A 0.0802 0.1915 0.191
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0042 0.0015 0.0008
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0042 0.0015 0.001
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0076 0.01 1
Echinococcus multilocularis kinase suppressor of Ras 1 0.0042 0.0015 0.001
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0042 0.0015 0.001
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0015 0.0008
Echinococcus multilocularis rac serine:threonine kinase 0.0076 0.01 0.0112
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.0067 0.0078 0.0072
Loa Loa (eye worm) TK/ROR protein kinase 0.0042 0.0015 0.0008
Schistosoma mansoni protein kinase 0.0058 0.0055 0.0041
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.006 0.006 0.0064
Brugia malayi serine/threonine protein kinase 6 0.0073 0.0093 0.0087
Entamoeba histolytica protein kinase, putative 0.0076 0.01 0.0559
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0042 0.0015 0.001
Brugia malayi Tyrosine-protein kinase abl-1 0.0042 0.0015 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0015 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis transfer RNA-Thr 0.0042 0.0015 0.001
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0042 0.0015 0.001
Trichomonas vaginalis centaurin alpha, putative 0.006 0.006 0.0387
Echinococcus multilocularis protein kinase 0.0042 0.0015 0.001
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.006 0.006 0.0064
Schistosoma mansoni centaurin alpha 0.006 0.006 0.0045
Echinococcus multilocularis protein KINase family member (kin 25) 0.0042 0.0015 0.001
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Leishmania major hypothetical protein, conserved 0.006 0.006 0.5267
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0654 0.1546 1
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Brugia malayi SRC-1 0.0042 0.0015 0.0008
Trypanosoma brucei protein kinase, putative 0.0058 0.0055 0.4733
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Schistosoma mansoni rhogef and pleckstrin domain protein 0.006 0.006 0.0045
Echinococcus multilocularis protein tyrosine kinase 0.0042 0.0015 0.001
Entamoeba histolytica p21-activated kinase 0.0076 0.01 0.0559
Loa Loa (eye worm) TK/DDR protein kinase 0.0042 0.0015 0.0008
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0042 0.0015 0.001
Trypanosoma cruzi hypothetical protein 0.006 0.006 0.5267
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.006 0.006 0.0387
Loa Loa (eye worm) TK/RYK protein kinase 0.0042 0.0015 0.0008
Schistosoma mansoni hypothetical protein 0.0126 0.0225 0.0211
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0042 0.0015 0.001
Loa Loa (eye worm) TK/EGFR protein kinase 0.0042 0.0015 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0073 0.0093 0.0079
Schistosoma mansoni hypothetical protein 0.006 0.006 0.0045
Trichomonas vaginalis centaurin/arf, putative 0.006 0.006 0.0387
Echinococcus granulosus tyrosine protein kinase csk 0.0042 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0063 0.0066 0.006
Schistosoma mansoni regulator of G protein signaling 0.0654 0.1546 0.1533
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Schistosoma mansoni zinc finger protein 0.006 0.006 0.0045
Echinococcus granulosus tyrosine kinase 0.0042 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0067 0.0078 0.0072
Brugia malayi Guanylyl cyclase protein 23 0.0042 0.0015 0.0008
Echinococcus granulosus Immunoglobulin 0.0063 0.0066 0.0072
Loa Loa (eye worm) rho-GTPase-activating 0.006 0.006 0.0053
Toxoplasma gondii hypothetical protein 0.006 0.006 0.5267
Echinococcus granulosus natriuretic peptide receptor 1 0.0042 0.0015 0.001
Brugia malayi Tyrosine-protein kinase PR2 0.0042 0.0015 0.0008
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0076 0.01 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Entamoeba histolytica protein kinase domain containing protein 0.0073 0.0093 0.0512
Brugia malayi probable spectrin beta chain 0.006 0.006 0.0053
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Entamoeba histolytica PH domain containing protein kinase, putative 0.0076 0.01 0.0559
Entamoeba histolytica PH domain containing protein kinase, putative 0.0076 0.01 0.0559
Loa Loa (eye worm) uncoordinated protein 104 0.006 0.006 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0058 0.0055 0.4733
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi MAX-1A 0.006 0.006 0.0053
Echinococcus multilocularis Pleckstrin y 0.006 0.006 0.0064
Echinococcus granulosus dynamin 1 0.006 0.006 0.0064
Brugia malayi integrin-linked kinase 0.0042 0.0015 0.0008
Leishmania major serine/threonine-protein kinase a, putative 0.0076 0.01 1
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.0055 0.0265
Trypanosoma cruzi hypothetical protein 0.006 0.006 0.5267
Loa Loa (eye worm) hypothetical protein 0.0063 0.0066 0.006
Trypanosoma cruzi Protein kinase B 0.0076 0.01 1
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Onchocerca volvulus Protein melted homolog 0.006 0.006 0.0284
Onchocerca volvulus 0.006 0.006 0.0284
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Entamoeba histolytica PH domain containing protein 0.006 0.006 0.0295
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis exocyst complex component 2 0.0126 0.0225 0.0262
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.006 0.006 0.0284
Plasmodium falciparum serine/threonine protein kinase, putative 0.0073 0.0093 0.9159
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0225 0.1456
Echinococcus multilocularis beta adrenergic receptor kinase 0.3092 0.7644 0.9139
Brugia malayi hypothetical protein 0.0288 0.0629 0.0623
Trypanosoma cruzi hypothetical protein 0.006 0.006 0.5267
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0126 0.0225 0.1456
Echinococcus granulosus defective proboscis extension response 0.0063 0.0066 0.0072
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0073 0.0093 0.0104
Loa Loa (eye worm) SRC-1 0.0042 0.0015 0.0008
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0042 0.0015 0.0095
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0042 0.0015 0.001
Brugia malayi SH2 domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis regulator of G protein signaling 0.0654 0.1546 0.1842
Entamoeba histolytica hypothetical protein 0.0126 0.0225 0.1374
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0654 0.1546 0.1842
Loa Loa (eye worm) TK/INSR protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) syntrophin-1 0.006 0.006 0.0053
Plasmodium falciparum calcium-dependent protein kinase 7 0.0076 0.01 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0042 0.0015 0.0008
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0105 0.0171 0.0165
Plasmodium falciparum protein kinase, putative 0.0058 0.0055 0.4733
Echinococcus multilocularis DCC interacting protein 13 beta 0.006 0.006 0.0064
Echinococcus multilocularis tyrosine protein kinase pr2 0.0042 0.0015 0.001
Trichomonas vaginalis alpha chimerin, putative 0.006 0.006 0.0387
Echinococcus multilocularis activated cdc42 kinase 1 0.0042 0.0015 0.001
Plasmodium vivax hypothetical protein, conserved 0.006 0.006 0.5267
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Echinococcus granulosus tyrosine protein kinase ABL1 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Entamoeba histolytica hypothetical protein 0.0654 0.1546 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0042 0.0015 0.001
Echinococcus granulosus tyrosine protein kinase HCK 0.0042 0.0015 0.001
Entamoeba histolytica protein kinase , putative 0.0073 0.0093 0.0512
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.006 0.5267
Echinococcus granulosus retinal guanylyl cyclase 2 0.0042 0.0015 0.001
Entamoeba histolytica protein kinase, putative 0.0076 0.01 0.0559
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0042 0.0015 0.001
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0076 0.01 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0042 0.0015 0.001
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.4034 1 1
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.006 0.006 0.0064
Entamoeba histolytica ARF GTPase activating protein, putative 0.006 0.006 0.0295
Echinococcus multilocularis FL cytokine receptor 0.0042 0.0015 0.001
Echinococcus multilocularis calcium dependent secretion activator 1 0.006 0.006 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.4034 1 1
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi Furin-like cysteine rich region family protein 0.0042 0.0015 0.0008
Echinococcus granulosus exocyst complex component 2 0.0126 0.0225 0.0262
Schistosoma mansoni cell adhesion molecule 0.0067 0.0078 0.0064
Echinococcus granulosus ephrin type A receptor 4 A 0.0042 0.0015 0.001
Schistosoma mansoni oxysterol-binding protein 1 0.006 0.006 0.0045
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.006 0.006 0.0064
Leishmania major protein kinase, putative 0.0073 0.0093 0.9159
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Echinococcus multilocularis tyrosine protein kinase shark 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus tyrosine protein kinase Blk 0.0042 0.0015 0.001
Echinococcus granulosus kinase suppressor of Ras 1 0.0042 0.0015 0.001
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.006 0.006 0.0064
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0126 0.0225 0.1456
Entamoeba histolytica hypothetical protein 0.0076 0.01 0.0559
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Onchocerca volvulus 0.0676 0.16 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0042 0.0015 0.001
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Echinococcus multilocularis axis inhibition protein axin 0.0654 0.1546 0.1842
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.006 0.006 0.0064
Echinococcus multilocularis cytohesin 1 0.006 0.006 0.0064
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0042 0.0015 0.0008
Entamoeba histolytica hypothetical protein 0.006 0.006 0.0295
Echinococcus multilocularis Immunoglobulin 0.0063 0.0066 0.0072
Echinococcus multilocularis heat shock protein 70 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0063 0.0066 0.0072
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Echinococcus granulosus myotubularin protein 13 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0654 0.1546 0.154
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.006 0.0295
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.0126 0.0225 0.0219
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0042 0.0015 0.0008
Brugia malayi GTP-ase activating protein for Arf containing protein 0.006 0.006 0.0053
Echinococcus multilocularis natriuretic peptide receptor 1 0.0042 0.0015 0.001
Entamoeba histolytica hypothetical protein 0.0654 0.1546 1
Echinococcus multilocularis semaphorin 5B 0.0288 0.0629 0.0745
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0654 0.1546 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Schistosoma mansoni regulator of G protein signaling 0.0654 0.1546 0.1533
Loa Loa (eye worm) sema domain-containing protein 0.0288 0.0629 0.0623
Trichomonas vaginalis protein tyrosine kinase, putative 0.0042 0.0015 0.0095
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0076 0.01 1
Echinococcus granulosus Regulator of G protein signaling 20 0.0654 0.1546 0.1842
Brugia malayi Immunoglobulin I-set domain containing protein 0.0067 0.0078 0.0072
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Giardia lamblia Aurora kinase 0.0073 0.0093 1
Echinococcus granulosus tyrosine protein kinase shark 0.0042 0.0015 0.001
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0076 0.01 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Echinococcus multilocularis neuroglian 0.0063 0.0066 0.0072
Brugia malayi hypothetical protein 0.0288 0.0629 0.0623
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0076 0.01 0.0649
Echinococcus granulosus DCC interacting protein 13 beta 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0654 0.1546 0.154
Echinococcus granulosus G protein coupled receptor kinase 1 0.2438 0.6008 0.7181
Echinococcus granulosus cytohesin 1 0.006 0.006 0.0064
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.006 0.5267
Loa Loa (eye worm) hypothetical protein 0.0229 0.0482 0.0476
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Schistosoma mansoni vesicular amine transporter 0.0065 0.0073 0.0058
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Schistosoma mansoni goodpasture antigen-binding protein 0.006 0.006 0.0045
Trypanosoma brucei rac serine-threonine kinase, putative 0.0076 0.01 1
Echinococcus granulosus activated cdc42 kinase 1 0.0042 0.0015 0.001
Echinococcus granulosus tyrosine protein kinase csk 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0225 0.1456
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0225 0.1456
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0042 0.0015 0.001
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.006 0.006 0.0064
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Echinococcus granulosus transcription factor collier 0.0126 0.0225 0.0262
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.006 0.006 0.0387
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis regulator of G protein signaling 7 0.0654 0.1546 0.1842
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.006 0.006 0.0064
Echinococcus granulosus twitchin 0.0079 0.0107 0.012
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus insulin receptor 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0225 0.1456
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0093 0.0602
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.338 0.8364 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.0042 0.0015 0.001
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus granulosus retinal guanylyl cyclase 2 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0095
Schistosoma mansoni syntrophin 0.006 0.006 0.0045
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0058 0.0055 0.4733
Schistosoma mansoni serine/threonine protein kinase 0.3092 0.7644 0.7641
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Loa Loa (eye worm) RhoGEF domain-containing protein 0.006 0.006 0.0053
Echinococcus multilocularis oxysterol binding protein 3 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0042 0.0015 0.0008
Entamoeba histolytica protein kinase, putative 0.0073 0.0093 0.0512
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0093 0.0602
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Echinococcus multilocularis myotubularin protein 13 0.006 0.006 0.0064
Leishmania major protein kinase, putative 0.0076 0.01 1
Entamoeba histolytica protein kinase, putative 0.0076 0.01 0.0559
Entamoeba histolytica PH domain containing protein 0.006 0.006 0.0295
Schistosoma mansoni protein kinase 0.0073 0.0093 0.0079
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Echinococcus granulosus roundabout 2 0.0067 0.0078 0.0086
Echinococcus multilocularis axis inhibition protein axin 0.0654 0.1546 0.1842
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Toxoplasma gondii hypothetical protein 0.006 0.006 0.5267
Brugia malayi hypothetical protein 0.0042 0.0015 0.0008
Trypanosoma brucei aurora B kinase 0.0073 0.0093 0.9159
Echinococcus granulosus integrin linked protein kinase 0.0042 0.0015 0.001
Echinococcus granulosus regulator of G protein signaling 3 0.0654 0.1546 0.1842
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.006 0.006 0.0064
Brugia malayi Variant SH3 domain containing protein 0.006 0.006 0.0053
Brugia malayi hypothetical protein 0.0654 0.1546 0.154
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Toxoplasma gondii Oxysterol-binding protein 0.006 0.006 0.5267
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0015 0.0008
Brugia malayi SH2 domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis tyrosine protein kinase 0.0042 0.0015 0.001
Leishmania major hypothetical protein, conserved 0.006 0.006 0.5267
Trichomonas vaginalis centaurin/arf, putative 0.006 0.006 0.0387
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0015 0.001
Echinococcus multilocularis epidermal growth factor receptor 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.006 0.006 0.0387
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.338 0.8364 0.8363
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0015 0.0001
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.006 0.006 0.0053
Schistosoma mansoni z-protein (S1r protein) 0.0654 0.1546 0.1533
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Brugia malayi hypothetical protein 0.0067 0.0078 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Loa Loa (eye worm) TK/ABL protein kinase 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0676 0.16 0.1595
Trichomonas vaginalis kinesin light chain, putative 0.006 0.006 0.0387
Onchocerca volvulus Putative zinc finger protein 0.006 0.006 0.0284
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) AUR protein kinase 0.0073 0.0093 0.0087
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Schistosoma mansoni hypothetical protein 0.0126 0.0225 0.0211
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0042 0.0015 0.0095
Entamoeba histolytica protein kinase domain containing protein 0.0168 0.033 0.206
Loa Loa (eye worm) hypothetical protein 0.0063 0.0066 0.006
Loa Loa (eye worm) cytohesin 3 0.006 0.006 0.0053
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Schistosoma mansoni hypothetical protein 0.006 0.006 0.0045
Plasmodium falciparum oxysterol-binding protein, putative 0.006 0.006 0.5267
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Echinococcus granulosus Pleckstrin domain containing protein family B 0.006 0.006 0.0064
Echinococcus granulosus activated cdc42 kinase 1 0.0042 0.0015 0.001
Brugia malayi C-terminal src kinase protein 1 0.0042 0.0015 0.0008
Entamoeba histolytica hypothetical protein 0.0126 0.0225 0.1374
Entamoeba histolytica hypothetical protein 0.006 0.006 0.0295
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0073 0.0093 0.0104
Entamoeba histolytica PH domain containing protein kinase, putative 0.0076 0.01 0.0559
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0042 0.0015 0.001
Echinococcus granulosus GRB2 associated binding protein 3 0.006 0.006 0.0064
Brugia malayi hypothetical protein 0.0654 0.1546 0.154
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis pleckstrin y domain containing family A 0.006 0.006 0.0064
Echinococcus granulosus neuroglian 0.0063 0.0066 0.0072
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Entamoeba histolytica protein kinase, putative 0.0073 0.0093 0.0512
Trichomonas vaginalis protein transport protein sec7, putative 0.006 0.006 0.0387
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis GRB2 associated binding protein 3 0.006 0.006 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus plexin a4 0.0802 0.1915 0.2284
Loa Loa (eye worm) hypothetical protein 0.0126 0.0225 0.0219
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0076 0.01 1
Brugia malayi PXA domain containing protein 0.0654 0.1546 0.154
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.006 0.006 0.5267
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0042 0.0015 0.001
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0076 0.01 1
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0225 0.1456
Schistosoma mansoni nephrin 0.0067 0.0078 0.0064
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.006 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0042 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Schistosoma mansoni ephrin receptor 0.0047 0.0027 0.0012
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.338 0.8364 0.8363
Echinococcus multilocularis Immunoglobulin 0.0063 0.0066 0.0072
Echinococcus granulosus tyrosine protein kinase Srms 0.0042 0.0015 0.001
Echinococcus multilocularis regulator of G protein signaling 7 0.0654 0.1546 0.1842
Entamoeba histolytica hypothetical protein 0.0126 0.0225 0.1374
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0076 0.01 1
Brugia malayi Plexin repeat family protein 0.0676 0.16 0.1595
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Echinococcus multilocularis dynamin 1 0.006 0.006 0.0064
Echinococcus granulosus axis inhibition protein axin 0.0654 0.1546 0.1842
Leishmania major protein kinase, putative 0.0076 0.01 1
Loa Loa (eye worm) sema domain-containing protein 0.0288 0.0629 0.0623
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Entamoeba histolytica hypothetical protein 0.006 0.006 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Echinococcus granulosus epidermal growth factor receptor 0.0042 0.0015 0.001
Echinococcus multilocularis tyrosine kinase 0.0042 0.0015 0.001
Plasmodium falciparum PH domain-containing protein, putative 0.006 0.006 0.5267
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis roundabout 2 0.0067 0.0078 0.0086
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0288 0.0629 0.0623
Brugia malayi GTP-ase activating protein for Arf containing protein 0.006 0.006 0.0053
Loa Loa (eye worm) TK/CSK protein kinase 0.0042 0.0015 0.0008
Echinococcus granulosus serine/threonine protein kinase 0.0076 0.01 0.0112
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0058 0.0055 0.4733
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Echinococcus granulosus expressed protein 0.0654 0.1546 0.1842
Loa Loa (eye worm) hypothetical protein 0.0063 0.0066 0.006
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Schistosoma mansoni hypothetical protein 0.006 0.006 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Brugia malayi Cadps2 protein 0.006 0.006 0.0053
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Brugia malayi IPT/TIG domain containing protein 0.0126 0.0225 0.0219
Entamoeba histolytica hypothetical protein 0.0654 0.1546 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0654 0.1546 0.154
Echinococcus multilocularis beta 1 syntrophin 0.006 0.006 0.0064
Schistosoma mansoni vav2 0.006 0.006 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0093 0.0602
Echinococcus granulosus protein kinase 0.0042 0.0015 0.001
Trypanosoma cruzi NIMA-related kinase, putative 0.0076 0.01 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0225 0.0219
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Brugia malayi hypothetical protein 0.0042 0.0015 0.0008
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus granulosus retinal guanylyl cyclase 2 0.0042 0.0015 0.001
Echinococcus multilocularis tyrosine protein kinase HCK 0.0042 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0126 0.0225 0.0219
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Loa Loa (eye worm) TK/EPH protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Schistosoma mansoni regulator of G protein signaling 0.0654 0.1546 0.1533
Leishmania major folate/biopterin transporter, putative 0.0076 0.01 1
Brugia malayi Variant SH3 domain containing protein 0.006 0.006 0.0053
Trichomonas vaginalis centaurin beta, putative 0.006 0.006 0.0387
Brugia malayi serine/threonine kinase 12 0.0073 0.0093 0.0087
Echinococcus granulosus oxysterol binding protein 9 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Onchocerca volvulus 0.006 0.006 0.0284
Echinococcus granulosus oxysterol binding protein 1 0.006 0.006 0.0064
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Schistosoma mansoni hypothetical protein 0.0288 0.0629 0.0616
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.006 0.5267
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Echinococcus multilocularis regulator of G protein signaling 3 0.0654 0.1546 0.1842
Echinococcus granulosus receptor type guanylyl cyclase 0.0042 0.0015 0.001
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0654 0.1546 0.154
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0654 0.1546 0.154
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0015 0.001
Schistosoma mansoni hypothetical protein 0.006 0.006 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.006 0.006 0.5267
Loa Loa (eye worm) variant SH3 domain-containing protein 0.006 0.006 0.0053
Echinococcus granulosus activin receptor type 0.0058 0.0055 0.0058
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0073 0.0093 0.0512
Brugia malayi hypothetical protein 0.0042 0.0015 0.0008
Schistosoma mansoni protein kinase 0.0058 0.0055 0.0041
Toxoplasma gondii phosphatidylinositol transfer protein 0.006 0.006 0.5267
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0042 0.0015 0.0095
Echinococcus multilocularis G protein coupled receptor kinase 6 0.338 0.8364 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0042 0.0015 0.001
Trichomonas vaginalis hypothetical protein 0.006 0.006 0.0387
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0042 0.0015 0.0008
Echinococcus multilocularis Pleckstrin y 0.006 0.006 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Echinococcus multilocularis Rho GTPase activating protein 24 0.006 0.006 0.0064
Schistosoma mansoni oxysterol-binding protein 1 0.006 0.006 0.0045
Echinococcus granulosus semaphorin 5B 0.0288 0.0629 0.0745
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Echinococcus granulosus regulator of G protein signaling 3 0.0654 0.1546 0.1842
Plasmodium vivax PH domain containing protein 0.006 0.006 0.5267
Echinococcus granulosus tyrosine kinase 0.0042 0.0015 0.001
Schistosoma mansoni myotubularin-related protein 0.006 0.006 0.0045
Entamoeba histolytica tyrosin kinase, putative 0.0168 0.033 0.206
Loa Loa (eye worm) TK/ACK protein kinase 0.0042 0.0015 0.0008
Brugia malayi Pleckstrin Homology Domain 0.006 0.006 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Entamoeba histolytica hypothetical protein 0.006 0.006 0.0295
Echinococcus granulosus tyrosine protein kinase pr2 0.0042 0.0015 0.001
Schistosoma mansoni axis inhibition protein axin 0.0654 0.1546 0.1533
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0126 0.0225 0.1456
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0063 0.0066 0.0052
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0076 0.01 1
Schistosoma mansoni protein kinase 0.0058 0.0055 0.0041
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0076 0.01 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0042 0.0015 0.001
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis oxysterol binding protein 9 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0126 0.0225 0.1456
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus tyrosine kinase 0.0042 0.0015 0.001
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.006 0.006 0.0064
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Echinococcus granulosus Rho GTPase activating protein 24 0.006 0.006 0.0064
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.006 0.006 0.5267
Brugia malayi Dynamin 0.006 0.006 0.0053
Echinococcus multilocularis tyrosine protein kinase Abl 0.0042 0.0015 0.001
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Echinococcus multilocularis G protein coupled receptor kinase 1 0.2438 0.6008 0.7181
Entamoeba histolytica hypothetical protein 0.0126 0.0225 0.1374
Brugia malayi regulator of G-protein signaling egl-10 0.0654 0.1546 0.154
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.006 0.0295
Schistosoma mansoni dynamin 0.006 0.006 0.0045
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis expressed protein 0.0654 0.1546 0.1842
Echinococcus multilocularis receptor type guanylyl cyclase 0.0042 0.0015 0.001
Schistosoma mansoni regulator of G protein signaling 0.0654 0.1546 0.1533
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Brugia malayi Cytohesin 3 0.006 0.006 0.0053
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Schistosoma mansoni goodpasture antigen-binding protein 0.006 0.006 0.0045
Brugia malayi Oxysterol-binding protein 0.006 0.006 0.0053
Brugia malayi Fibronectin type III domain containing protein 0.0067 0.0078 0.0072
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0042 0.0015 0.001
Entamoeba histolytica protein kinase, putative 0.0076 0.01 0.0559
Trypanosoma brucei PH domain containing protein, putative 0.006 0.006 0.5267
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Echinococcus multilocularis tyrosine kinase 0.0042 0.0015 0.001
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi Protein kinase domain containing protein 0.0302 0.0666 0.066
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0015 0.0008
Brugia malayi ephrin receptor 1 precursor 0.0042 0.0015 0.0008
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0076 0.01 1
Schistosoma mansoni dynamin 0.006 0.006 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi hypothetical protein 0.006 0.006 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0042 0.0015 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Echinococcus granulosus regulator of G protein signaling 7 0.0654 0.1546 0.1842
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0015 0.001
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0042 0.0015 0.001
Loa Loa (eye worm) TK/ALK protein kinase 0.0302 0.0665 0.0659
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0042 0.0015 0.0008
Brugia malayi Oxysterol binding protein 0.006 0.006 0.0053
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Echinococcus multilocularis oxysterol binding protein 1 0.006 0.006 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis Ras associated and pleckstrin y 0.006 0.006 0.0064
Entamoeba histolytica PH domain containing protein kinase, putative 0.0076 0.01 0.0559
Entamoeba histolytica cell surface protease gp63, putative 0.0126 0.0225 0.1374
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.006 0.006 0.5267
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.006 0.0295
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0063 0.0066 0.0052
Schistosoma mansoni serine/threonine-protein kinase 0.0076 0.01 0.0086
Echinococcus granulosus Oxysterol binding protein 11 0.006 0.006 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi Syntrophin-1 0.006 0.006 0.0053
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Schistosoma mansoni rho gtpase activating protein 0.006 0.006 0.0045
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0076 0.01 1
Trypanosoma cruzi NIMA-related kinase, putative 0.0076 0.01 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0388 0.088 0.0875
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0058 0.0055 0.0058
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.0027 0.0024
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.006 0.5267
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0654 0.1546 0.1842
Brugia malayi TBC domain containing protein 0.006 0.006 0.0053
Loa Loa (eye worm) PH domain-containing protein 0.006 0.006 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Onchocerca volvulus 0.006 0.006 0.0284
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.006 0.006 0.0387
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0076 0.01 1
Brugia malayi regulator of G-protein signaling rgs-7 0.0654 0.1546 0.154
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0095
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Echinococcus granulosus tyrosine protein kinase Lyn 0.0058 0.0055 0.0058
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0073 0.0093 0.0512
Echinococcus multilocularis hypothetical protein 0.0288 0.0629 0.0745
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Brugia malayi serine/threonine-protein kinase 6 0.0073 0.0093 0.0087
Loa Loa (eye worm) AUR protein kinase 0.0073 0.0093 0.0087
Loa Loa (eye worm) hypothetical protein 0.0654 0.1546 0.154
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0225 0.1456
Entamoeba histolytica hypothetical protein, conserved 0.006 0.006 0.0295
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0095
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.006 0.006 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0095
Loa Loa (eye worm) oxysterol binding protein 0.006 0.006 0.0053
Loa Loa (eye worm) hypothetical protein 0.0063 0.0066 0.006
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0076 0.01 1
Echinococcus granulosus tyrosine protein kinase 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0654 0.1546 1
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0654 0.1546 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0654 0.1546 0.154
Echinococcus multilocularis tyrosine protein kinase csk 0.0042 0.0015 0.001
Schistosoma mansoni hypothetical protein 0.0288 0.0629 0.0616
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Brugia malayi Protein kinase domain containing protein 0.0076 0.01 0.0094
Onchocerca volvulus outspread protein homolog 0.006 0.006 0.0284
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.006 0.006 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Brugia malayi Receptor family ligand binding region containing protein 0.0042 0.0015 0.0008
Entamoeba histolytica PH domain containing protein kinase, putative 0.0076 0.01 0.0559
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0654 0.1546 0.1533
Echinococcus multilocularis tyrosine protein kinase Srms 0.0042 0.0015 0.001
Echinococcus granulosus epidermal growth factor receptor 0.0042 0.0015 0.001
Echinococcus granulosus Pleckstrin y 0.006 0.006 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Onchocerca volvulus 0.006 0.006 0.0284
Loa Loa (eye worm) PXA domain-containing protein 0.0654 0.1546 0.154
Toxoplasma gondii AtPH1 family protein 0.006 0.006 0.5267
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Brugia malayi protein-tyrosine kinase 0.0042 0.0015 0.0008
Echinococcus multilocularis transcription factor collier 0.0126 0.0225 0.0262
Echinococcus granulosus axis inhibition protein axin 0.0654 0.1546 0.1842
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0076 0.01 1
Echinococcus granulosus Pleckstrin y 0.006 0.006 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0058 0.0055 0.0058
Trypanosoma cruzi aurora B kinase, putative 0.0073 0.0093 0.9159
Brugia malayi bone morphogenetic protein type 1 receptor 0.0042 0.0015 0.0008
Echinococcus multilocularis aurora kinase A 0.0073 0.0093 0.0104
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0015 0.001
Schistosoma mansoni guanyl-nucleotide exchange factor 0.006 0.006 0.0045
Schistosoma mansoni plexin 0.0676 0.16 0.1588
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) RGS-3 protein 0.0654 0.1546 0.154
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0076 0.01 0.0649
Entamoeba histolytica protein kinase, putative 0.0076 0.01 0.0559
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.006 0.006 0.0064
Echinococcus multilocularis insulin receptor 0.0042 0.0015 0.001
Echinococcus multilocularis activin receptor type 0.0058 0.0055 0.0058
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.006 0.006 0.0053
Echinococcus granulosus semaphorin 1A 0.0288 0.0629 0.0745
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0126 0.0225 0.1456
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.006 0.006 0.0053
Loa Loa (eye worm) TK protein kinase 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0654 0.1546 1
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.006 0.006 0.0295
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.0027 0.0024
Echinococcus granulosus beta-adrenergic receptor kinase 0.3092 0.7644 0.9139
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0073 0.0093 0.0512
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.006 0.006 0.0045
Leishmania major protein kinase, putative 0.0058 0.0055 0.4733
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0105 0.0171 0.0165
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0042 0.0015 0.001
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.006 0.006 0.0387
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0076 0.01 1
Echinococcus multilocularis plexin a4 0.0802 0.1915 0.2284
Trypanosoma cruzi hypothetical protein 0.006 0.006 0.5267
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Trichomonas vaginalis STE family protein kinase 0.0042 0.0015 0.0095
Echinococcus granulosus aurora kinase A 0.0073 0.0093 0.0104
Brugia malayi Regulator of G protein signaling domain containing protein 0.0654 0.1546 0.154
Trichomonas vaginalis conserved hypothetical protein 0.0654 0.1546 1
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0015 0.0008
Echinococcus granulosus tyrosine protein kinase csk 0.0042 0.0015 0.001
Loa Loa (eye worm) TK/Met protein kinase 0.0042 0.0015 0.0008
Schistosoma mansoni serine/threonine-protein kinase 0.0076 0.01 0.0086
Echinococcus granulosus tyrosine protein kinase Src42A 0.0042 0.0015 0.001
Loa Loa (eye worm) AGC/AKT protein kinase 0.0076 0.01 0.0094
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0042 0.0015 0.001
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Loa Loa (eye worm) hypothetical protein 0.0288 0.0629 0.0623
Trichomonas vaginalis conserved hypothetical protein 0.0654 0.1546 1
Trichomonas vaginalis conserved hypothetical protein 0.006 0.006 0.0387
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0042 0.0015 0.0008
Onchocerca volvulus 0.006 0.006 0.0284
Onchocerca volvulus 0.006 0.006 0.0284
Echinococcus multilocularis pdz domain containing protein 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0288 0.0629 0.0623
Echinococcus granulosus oxysterol binding protein 3 0.006 0.006 0.0064
Brugia malayi A-kinase anchor protein 10, precursor 0.0654 0.1546 0.154
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.3092 0.7644 0.7641
Loa Loa (eye worm) hypothetical protein 0.0288 0.0629 0.0623
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0042 0.0015 0.001
Schistosoma mansoni hypothetical protein 0.0388 0.088 0.0867
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Loa Loa (eye worm) AUR protein kinase 0.0073 0.0093 0.0087
Echinococcus multilocularis regulator of G protein signaling 3 0.0654 0.1546 0.1842
Trichomonas vaginalis centaurin gamma, putative 0.006 0.006 0.0387
Echinococcus multilocularis protein kinase 0.0042 0.0015 0.001
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.006 0.006 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0073 0.0093 0.9159
Echinococcus granulosus c src tyrosine kinase 0.0042 0.0015 0.001
Brugia malayi Plekhf2 protein 0.006 0.006 0.0053
Echinococcus granulosus raf serine:threonine protein kinase 0.0042 0.0015 0.001
Brugia malayi Dynamin 0.006 0.006 0.0053
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0042 0.0015 0.0008
Echinococcus granulosus Pleckstrin y 0.006 0.006 0.0064
Brugia malayi Protein kinase domain containing protein 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0126 0.0225 0.1456
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0042 0.0015 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0015 0.0095
Echinococcus multilocularis Regulator of G protein signaling 20 0.0654 0.1546 0.1842
Echinococcus granulosus calcium dependent secretion activator 1 0.006 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0042 0.0015 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Entamoeba histolytica protein kinase, putative 0.0076 0.01 0.0559
Brugia malayi plexin A 0.0802 0.1915 0.191
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.006 0.006 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0042 0.0015 0.0095
Brugia malayi Probable exocyst complex component Sec5 0.0126 0.0225 0.0219
Loa Loa (eye worm) hypothetical protein 0.0654 0.1546 0.154
Brugia malayi PH domain containing protein 0.006 0.006 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0076 0.01 0.0649
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0654 0.1546 0.1533
Entamoeba histolytica PH domain containing protein 0.006 0.006 0.0295
Echinococcus multilocularis Oxysterol binding protein 11 0.006 0.006 0.0064
Trypanosoma cruzi hypothetical protein 0.006 0.006 0.5267
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.3092 0.7644 0.7643
Schistosoma mansoni hypothetical protein 0.006 0.006 0.0045
Schistosoma mansoni plexin 0.0388 0.088 0.0867
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.006 0.006 0.5267
Echinococcus granulosus regulator of G protein signaling 7 0.0654 0.1546 0.1842
Schistosoma mansoni semaphorin 5-related 0.0288 0.0629 0.0616
Loa Loa (eye worm) hypothetical protein 0.0067 0.0078 0.0072
Schistosoma mansoni axis inhibition protein axin 0.0654 0.1546 0.1533
Entamoeba histolytica PH domain containing protein kinase, putative 0.0076 0.01 0.0559
Toxoplasma gondii protein kinase domain-containing protein 0.0076 0.01 1
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.006 0.0295
Onchocerca volvulus 0.0288 0.0629 0.3877

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 23.1093 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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