Detailed information for compound 1407656

Basic information

Technical information
  • TDR Targets ID: 1407656
  • Name: 3-(2-furan-2-yl-2-oxoethyl)-3-hydroxy-1-(2-ph enylethyl)indol-2-one
  • MW: 361.391 | Formula: C22H19NO4
  • H donors: 1 H acceptors: 3 LogP: 3.44 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1N(CCc2ccccc2)c2c(C1(O)CC(=O)c1ccco1)cccc2
  • InChi: 1S/C22H19NO4/c24-19(20-11-6-14-27-20)15-22(26)17-9-4-5-10-18(17)23(21(22)25)13-12-16-7-2-1-3-8-16/h1-11,14,26H,12-13,15H2
  • InChiKey: WUFBWMAXHHZRJV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[2-(2-furyl)-2-oxo-ethyl]-3-hydroxy-1-(2-phenylethyl)indolin-2-one
  • 3-[2-(2-furyl)-2-oxoethyl]-3-hydroxy-1-(2-phenylethyl)-2-indolinone
  • 3-[2-(2-furyl)-2-keto-ethyl]-3-hydroxy-1-(2-phenylethyl)oxindole
  • 3-(2-furan-2-yl-2-oxo-ethyl)-3-hydroxy-1-(2-phenylethyl)indol-2-one
  • MLS000113583
  • SMR000109480
  • STK216826
  • Oprea1_607949
  • EU-0081167

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0154 0.0318
Onchocerca volvulus 0.003 0.004 0.0122
Schistosoma mansoni adapter molecule crk 0.0025 0.0015 0.0015
Echinococcus granulosus cyclins 0.0039 0.0081 0.0081
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0032 0.0049 0.01
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0213 0.0874 0.0874
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.046 0.2008 0.413
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Echinococcus multilocularis endonuclease reverse transcriptase 0.0029 0.0033 0.0033
Echinococcus granulosus protein kinase c iota type 0.0032 0.0049 0.0049
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Echinococcus granulosus activin receptor type 0.0039 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.023
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0131 0.0501 0.0501
Echinococcus granulosus tyrosine protein kinase HCK 0.0095 0.0334 0.0334
Brugia malayi Cyclin, N-terminal domain containing protein 0.0039 0.0081 0.0192
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Entamoeba histolytica tyrosin kinase, putative 0.0037 0.0072 0.0521
Echinococcus multilocularis enteropeptidase 0.0039 0.0079 0.0079
Brugia malayi Immunoglobulin I-set domain containing protein 0.0814 0.3624 0.8584
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0256 0.1074 0.7801
Echinococcus multilocularis muscleblind protein 0.046 0.2008 0.2008
Brugia malayi Cyclin, N-terminal domain containing protein 0.0039 0.0081 0.0192
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.003 0.004 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0162
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0001
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.003 0.0041 0.0085
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0448 0.0448
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1518 0.6844 1
Brugia malayi Guanylyl cyclase protein 23 0.003 0.004 0.0094
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0501 0.0639
Brugia malayi Protein kinase domain containing protein 0.0032 0.0049 0.0115
Brugia malayi Receptor family ligand binding region containing protein 0.003 0.004 0.0094
Echinococcus multilocularis tyrosine protein kinase pr2 0.003 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0075 0.0247 0.0507
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0103 0.0374 0.3278
Entamoeba histolytica protein kinase, putative 0.0256 0.1074 0.7801
Schistosoma mansoni serine/threonine-protein kinase 0.0059 0.0171 0.0171
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0501 0.0501
Plasmodium vivax protein kinase, putative 0.004 0.0083 0.0772
Loa Loa (eye worm) AUR protein kinase 0.0256 0.1074 0.221
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0086 0.0297 0.0612
Loa Loa (eye worm) TK protein kinase 0.0095 0.0334 0.0688
Brugia malayi Plexin repeat family protein 0.0038 0.0076 0.0181
Giardia lamblia Hypothetical protein 0.0039 0.0081 0.0357
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.005 0.0131 0.011
Brugia malayi TAR-binding protein 0.0062 0.0184 0.0436
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0037 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0082
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0000090787 0.0000090787
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0059 0.0171 0.098
Echinococcus granulosus roundabout 2 0.0127 0.0481 0.0481
Brugia malayi Trypsin family protein 0.0039 0.0079 0.0187
Echinococcus multilocularis cyclins 0.0039 0.0081 0.0081
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0618 0.4488
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0003 0.0003
Entamoeba histolytica PH domain containing protein kinase, putative 0.0059 0.0171 0.1241
Schistosoma mansoni ephrin receptor 0.0043 0.0097 0.0097
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0003 0.0003
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0015 0.0035
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.003 0.004 0.0082
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.1377 0.1377
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0163
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Entamoeba histolytica cyclin family protein 0.0039 0.0081 0.0589
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0039 0.0079 0.0244
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0078
Toxoplasma gondii protein kinase domain-containing protein 0.003 0.004 0.0063
Echinococcus multilocularis growth factor receptor bound protein 2 0.0025 0.0015 0.0015
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.005 0.0131 0.0681
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0022 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0412 0.2996
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0448 0.0448
Loa Loa (eye worm) AUR protein kinase 0.0256 0.1074 0.221
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.003 0.004 0.0288
Brugia malayi Pre-SET motif family protein 0.0234 0.0972 0.2303
Schistosoma mansoni tyrosine kinase 0.0639 0.2826 0.2826
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1377 1
Trypanosoma cruzi cyclin 6, putative 0.0039 0.0081 0.031
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0119 0.0448 0.0448
Schistosoma mansoni rab6-interacting 0.0022 0.0000090787 0.0000090787
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0077 0.0256 0.0526
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0081 0.0308
Brugia malayi serine/threonine-protein kinase 6 0.0256 0.1074 0.2545
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0039 0.0079 0.0079
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0003 0.0003
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.004 0.004
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0068 0.0628
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.003 0.0041 0.0098
Echinococcus multilocularis raf serine:threonine protein kinase 0.003 0.004 0.004
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1518 0.6844 1
Schistosoma mansoni rab6-interacting 0.0022 0.0000090787 0.0000090787
Echinococcus multilocularis Immunoglobulin 0.0022 0.0001 0.0001
Echinococcus multilocularis epidermal growth factor receptor 0.0944 0.4221 0.4221
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0031
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0124 0.0255
Schistosoma mansoni tyrosine-protein kinase fps85d 0.003 0.004 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0087
Plasmodium falciparum casein kinase 2, alpha subunit 0.0157 0.0618 0.5753
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.003 0.004 0.004
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.0001 0.0001
Echinococcus granulosus NDR protein kinase 0.0032 0.0049 0.0049
Toxoplasma gondii aldehyde dehydrogenase 0.0131 0.0501 0.449
Echinococcus multilocularis tyrosine protein kinase Blk 0.0107 0.0392 0.0392
Brugia malayi steroid hormone receptor 0.0022 0.0003 0.0006
Echinococcus granulosus contactin 0.0051 0.0137 0.0137
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.1049 0.1049
Echinococcus granulosus neuroglian 0.0051 0.0137 0.0137
Schistosoma mansoni peroxidasin 0.0022 0.0001 0.0001
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0045 0.0109 0.0109
Schistosoma mansoni serine/threonine-protein kinase 0.0059 0.0171 0.0171
Trypanosoma cruzi Protein kinase B 0.0059 0.0171 0.098
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0039 0.0079 0.0079
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni cyclin B 0.0039 0.0081 0.0081
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0177 0.0177
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0501 0.0639
Echinococcus multilocularis cyclin B3 1 0.0039 0.0081 0.0081
Trypanosoma brucei aurora B kinase 0.0256 0.1074 0.7736
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0448 0.0448
Schistosoma mansoni titin 0.003 0.0037 0.0037
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0103 0.0374 0.077
Brugia malayi Immunoglobulin domain containing protein 0.0022 0.0001 0.0003
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0082
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0051 0.0137 0.0281
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0037 0.0076
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0119 0.0448 0.0448
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.003 0.004 0.0063
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0022 0.0001 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0079 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0049
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0124 0.0898
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0082
Echinococcus granulosus expressed conserved protein 0.0189 0.0768 0.0768
Echinococcus granulosus tyrosine protein kinase Src42A 0.0119 0.0448 0.0448
Entamoeba histolytica protein kinase, putative 0.0077 0.0256 0.1858
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0078
Echinococcus multilocularis cyclins 0.0039 0.0081 0.0081
Brugia malayi Fibronectin type III domain containing protein 0.0088 0.0304 0.0719
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.004
Onchocerca volvulus 0.0043 0.0097 0.0298
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0058 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0096 0.0096
Entamoeba histolytica tyrosin kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis fibroblast growth factor receptor 4 0.003 0.004 0.004
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.005 0.0131 0.0938
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0087
Echinococcus multilocularis protein KINase family member (kin 25) 0.003 0.004 0.004
Giardia lamblia Kinase, CMGC CDK 0.0103 0.0374 0.254
Onchocerca volvulus 0.0266 0.1119 0.3437
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1377 1
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0137 0.0323
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0374 0.2719
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus tyrosine kinase 0.003 0.004 0.004
Entamoeba histolytica receptor protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni nephrin 0.0051 0.0137 0.0137
Entamoeba histolytica PH domain containing protein kinase, putative 0.0059 0.0171 0.1241
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0124 0.0083
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0163
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Echinococcus granulosus plexin a4 0.0045 0.0108 0.0108
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0043 0.0097 0.0097
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0068 0.0628
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0058 0.0058
Echinococcus granulosus tyrosine kinase 0.0043 0.0097 0.0097
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0043 0.0097 0.0097
Plasmodium falciparum protein kinase, putative 0.003 0.004 0.0369
Schistosoma mansoni septate junction protein 0.0022 0.0001 0.0001
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.003 0.004 0.0288
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Onchocerca volvulus 0.003 0.004 0.0122
Echinococcus multilocularis cyclin b3 0.0039 0.0081 0.0081
Brugia malayi protein unc-22 0.0039 0.0078 0.0185
Schistosoma mansoni hemicentin 0.003 0.0037 0.0037
Schistosoma mansoni cyclin B3 0.0039 0.0081 0.0081
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0589
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0589
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0087
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0054 0.015 0.1396
Echinococcus granulosus cyclin dependent kinase 1 0.0103 0.0374 0.0374
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.023
Echinococcus multilocularis sterol regulatory element binding protein 0.0086 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0039 0.0079 0.0079
Loa Loa (eye worm) TK/Met protein kinase 0.003 0.004 0.0082
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni cell adhesion molecule 0.003 0.0037 0.0037
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0025 0.0015 0.0031
Echinococcus granulosus Mastin 0.0039 0.0079 0.0079
Plasmodium falciparum cysteine repeat modular protein 3 0.0029 0.0033 0.0307
Schistosoma mansoni hypothetical protein 0.0083 0.0283 0.0283
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.1049 0.1049
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0003 0.0008
Brugia malayi Immunoglobulin domain containing protein 0.0022 0.0001 0.0003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.0972 0.2
Echinococcus multilocularis FL cytokine receptor 0.003 0.004 0.004
Brugia malayi Muscleblind-like protein 0.046 0.2008 0.4756
Echinococcus granulosus Immunoglobulin subtype 0.0022 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Schistosoma mansoni hypothetical protein 0.003 0.0037 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1377 1
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0039 0.0079 0.0079
Trypanosoma brucei Casein kinase II 0.0157 0.0618 0.4325
Schistosoma mansoni lipoxygenase 0.006 0.0177 0.0177
Brugia malayi Protein kinase domain containing protein 0.0593 0.2614 0.6193
Schistosoma mansoni protein kinase 0.0256 0.1074 0.1074
Schistosoma mansoni serine/threonine RGC 0.003 0.004 0.004
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.005 0.0131 0.0131
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Schistosoma mansoni tyrosine kinase 0.0119 0.0448 0.0448
Loa Loa (eye worm) TK/RYK protein kinase 0.003 0.004 0.0082
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0078
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Toxoplasma gondii aurora kinase 0.0256 0.1074 1
Entamoeba histolytica cyclin, putative 0.0039 0.0081 0.0589
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0082
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.003 0.004 0.0288
Echinococcus multilocularis protein tyrosine kinase 0.0586 0.2584 0.2584
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0124 0.0898
Schistosoma mansoni cell adhesion molecule 0.011 0.0403 0.0403
Trichomonas vaginalis set domain proteins, putative 0.0266 0.1119 0.813
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0082
Onchocerca volvulus 0.0121 0.0453 0.1392
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0124 0.0083
Echinococcus granulosus tyrosine protein kinase Fyn 0.0119 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0036 0.0068 0.0139
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Echinococcus multilocularis tyrosine protein kinase HCK 0.0095 0.0334 0.0334
Trypanosoma cruzi cyclin, putative 0.0039 0.0081 0.031
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0003 0.0008
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Entamoeba histolytica hypothetical protein 0.0029 0.0033 0.024
Trichomonas vaginalis serine-threonine protein kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Echinococcus granulosus casein kinase ii subunit alpha 0.0157 0.0618 0.0618
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0154 0.0366
Echinococcus multilocularis cyclins 0.0039 0.0081 0.0081
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Entamoeba histolytica protein kinase, putative 0.0082 0.0277 0.2008
Trypanosoma cruzi cdc2-related kinase 1 0.0103 0.0374 0.2503
Onchocerca volvulus 0.0043 0.0097 0.0298
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0003 0.0006
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.003 0.004 0.0082
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0000090787 0.0000090787
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0618 0.4488
Brugia malayi Protein kinase domain containing protein 0.0346 0.1483 0.3513
Loa Loa (eye worm) TK protein kinase 0.0047 0.0118 0.0242
Trichomonas vaginalis protein tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis roundabout 2 0.0051 0.0137 0.0137
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0087
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.0079 0.0163
Echinococcus multilocularis protein kinase 0.003 0.004 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0079 0.0188
Trichomonas vaginalis AGC family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0058 0.012
Toxoplasma gondii hypothetical protein 0.003 0.0038 0.0045
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trypanosoma cruzi cyclin, putative 0.0039 0.0081 0.031
Echinococcus granulosus basement membrane specific heparan sulfate 0.0022 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Srms 0.0107 0.0392 0.0392
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Echinococcus granulosus Immunoglobulin 0.0022 0.0001 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0184 0.0184
Brugia malayi Raf kinase 0.003 0.004 0.0094
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0124 0.0628
Loa Loa (eye worm) hypothetical protein 0.0106 0.0386 0.0795
Brugia malayi Immunoglobulin I-set domain containing protein 0.0047 0.0118 0.0279
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0177 0.0177
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0082
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Giardia lamblia Protein 21.1 0.003 0.004 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0003 0.0003
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni kinase 0.0466 0.2032 0.2032
Echinococcus multilocularis cyclin dependent kinase 1 0.0103 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0003
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus fibroblast growth factor receptor 4 0.003 0.004 0.004
Schistosoma mansoni atypical protein kinase C 0.0032 0.0049 0.0049
Echinococcus multilocularis muscleblind protein 1 0.046 0.2008 0.2008
Trypanosoma cruzi CYC2-like cyclin, putative 0.0039 0.0081 0.031
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trichomonas vaginalis STE family protein kinase 0.003 0.004 0.0288
Brugia malayi Trypsin family protein 0.0039 0.0079 0.0187
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0003 0.0003
Loa Loa (eye worm) projectin 0.003 0.0037 0.0076
Echinococcus granulosus tyrosine protein kinase pr2 0.003 0.004 0.004
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.004 0.004
Toxoplasma gondii AGC kinase 0.0077 0.0256 0.2139
Loa Loa (eye worm) hypothetical protein 0.0088 0.0304 0.0625
Echinococcus multilocularis 0.028 0.1181 0.1181
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0034 0.0058 0.0058
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0003 0.0003
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0054 0.015 0.015
Echinococcus multilocularis transmembrane protease serine 3 0.0039 0.0079 0.0079
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0039 0.0078 0.0161
Entamoeba histolytica receptor protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) serine/threonine protein kinase 0.003 0.004 0.0082
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Echinococcus granulosus dnaJ subfamily B 0.0404 0.1748 0.1748
Onchocerca volvulus 0.0023 0.0009 0.0028
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0124 0.0083
Echinococcus granulosus nervana 2 0.0045 0.0109 0.0109
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0003 0.0005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.003 0.004 0.004
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0003 0.0003
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0023 0.0007 0.0054
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus peroxidasin 0.0039 0.0079 0.0079
Echinococcus multilocularis protein kinase 0.003 0.004 0.004
Schistosoma mansoni coup transcription factor 0.0022 0.0003 0.0003
Schistosoma mansoni septate junction protein 0.0039 0.0079 0.0079
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0000090787 0.0000090787
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.0374 0.2719
Onchocerca volvulus Serine\/threonine kinase homolog 0.0323 0.1377 0.4227
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.003 0.004 0.0288
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) AUR protein kinase 0.0256 0.1074 0.221
Trypanosoma cruzi polo-like protein kinase, putative 0.0323 0.1377 1
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0001 0.0001
Entamoeba histolytica tyrosin kinase, putative 0.003 0.004 0.0288
Plasmodium vivax SET domain protein, putative 0.0034 0.0058 0.0536
Echinococcus granulosus Immunoglobulin 0.0075 0.0247 0.0247
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0054 0.015 0.1396
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0003
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Brugia malayi Probable tyrosine-protein kinase kin-31 0.003 0.004 0.0094
Schistosoma mansoni tyrosine kinase 0.0069 0.0217 0.0217
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.003 0.004 0.004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0154 0.0154
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0051 0.0137 0.0137
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.1748 0.1748
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0082
Echinococcus granulosus cyclins 0.0039 0.0081 0.0081
Trichomonas vaginalis TK family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Echinococcus multilocularis cyclins 0.0039 0.0081 0.0081
Schistosoma mansoni growth factor receptor-bound protein 0.0025 0.0015 0.0015
Brugia malayi hypothetical protein 0.0043 0.0097 0.023
Schistosoma mansoni hypothetical protein 0.0083 0.0283 0.0283
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0103 0.0374 0.0374
Schistosoma mansoni hypothetical protein 0.0083 0.0283 0.0283
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0082
Echinococcus multilocularis transfer RNA-Phe 0.003 0.0037 0.0037
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.0001 0.0001
Onchocerca volvulus 0.0147 0.0575 0.1766
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0255 0.1068 0.1068
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0055 0.0153 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0003 0.0006
Trypanosoma cruzi cdc2-related kinase 3 0.0103 0.0374 0.2503
Entamoeba histolytica hypothetical protein 0.0029 0.0033 0.024
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0051 0.0137 0.0137
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Brugia malayi p70 ribosomal S6 kinase beta 0.0077 0.0256 0.0606
Schistosoma mansoni hypothetical protein 0.0165 0.0657 0.0657
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0277 0.2008
Schistosoma mansoni vesicular amine transporter 0.0075 0.0247 0.0247
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Mycobacterium ulcerans aldehyde dehydrogenase 0.0131 0.0501 0.0639
Echinococcus multilocularis cyclin dependent kinase 0.0103 0.0374 0.0374
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0124 0.0293
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0107 0.0392 0.0392
Echinococcus multilocularis epidermal growth factor receptor 0.0639 0.2826 0.2826
Echinococcus multilocularis tyrosine protein kinase Abl 0.0055 0.0153 0.0153
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0589
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.005 0.0131 0.0681
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Echinococcus granulosus raf serine:threonine protein kinase 0.003 0.004 0.004
Echinococcus multilocularis expressed conserved protein 0.0189 0.0768 0.0768
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0119 0.0448 0.0448
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0119 0.0448 0.0448
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0082
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0124 0.0628
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni hypothetical protein 0.0022 0.0000090787 0.0000090787
Loa Loa (eye worm) TK protein kinase 0.0107 0.0392 0.0806
Loa Loa (eye worm) TK/KIN6 protein kinase 0.003 0.004 0.0082
Schistosoma mansoni patched 1 0.0086 0.0297 0.0297
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Loa Loa (eye worm) hypothetical protein 0.0251 0.1049 0.2157
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus aurora kinase A 0.0256 0.1074 0.1074
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis heat shock protein 70 0.003 0.004 0.004
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0003 0.0003
Schistosoma mansoni cyclins 0.0039 0.0081 0.0081
Schistosoma mansoni serine/threonine kinase 0.0032 0.0049 0.0049
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0589
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0162
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Echinococcus multilocularis titin 0.0039 0.0078 0.0078
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.003 0.004 0.0094
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0003 0.0003
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.003 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus tyrosine kinase 0.0107 0.0392 0.0392
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0022 0.0001 0.0001
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0824 0.367 0.367
Trichomonas vaginalis cyclin B, putative 0.0039 0.0081 0.0589
Echinococcus granulosus cyclin b3 0.0039 0.0081 0.0081
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.005 0.0131 0.095
Plasmodium falciparum conserved protein, unknown function 0.0029 0.0033 0.0307
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) LAD-2 short isoform 0.0022 0.0001 0.0003
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0043 0.0097 0.0097
Onchocerca volvulus Tyrosine kinase homolog 0.0734 0.3257 1
Onchocerca volvulus 0.0039 0.0079 0.0242
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0032 0.0049 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0079 0.0188
Echinococcus multilocularis c src tyrosine kinase 0.0055 0.0153 0.0153
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni basigin related 0.0022 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.0034 0.0058 0.0137
Echinococcus granulosus activated cdc42 kinase 1 0.003 0.004 0.004
Echinococcus multilocularis glycoprotein Antigen 5 0.0039 0.0079 0.0079
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Echinococcus multilocularis cyclins 0.0039 0.0081 0.0081
Echinococcus granulosus roundabout 2 0.0051 0.0137 0.0137
Giardia lamblia Kinase, NEK 0.003 0.004 0.0049
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.0079 0.0163
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.005 0.0131 0.095
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Schistosoma mansoni nephrin 0.0105 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0205 0.0838 0.0838
Schistosoma mansoni cell adhesion molecule 0.0022 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0609 0.2688 0.2688
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0256 0.1074 0.7801
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0639 0.2826 0.2826
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0124 0.0898
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0124 0.0083
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Echinococcus granulosus beta-adrenergic receptor kinase 0.003 0.0041 0.0041
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0124 0.0628
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis cyclin A, putative 0.0039 0.0081 0.0589
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Schistosoma mansoni tyrosine kinase 0.0944 0.4221 0.4221
Brugia malayi Furin-like cysteine rich region family protein 0.0944 0.4221 1
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0033 0.0054 0.0054
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0000090787 0.0000090787
Schistosoma mansoni nck2/grb4 0.0025 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0119 0.0448 0.0448
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trypanosoma brucei cdc2-related kinase 3 0.0103 0.0374 0.2503
Giardia lamblia Kinase, PLK 0.0323 0.1377 1
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0003 0.0008
Echinococcus granulosus cyclin B3 1 0.0039 0.0081 0.0081
Echinococcus multilocularis cpg binding protein 0.003 0.0039 0.0039
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1377 1
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0103 0.0374 0.2503
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0256 0.1074 0.1074
Echinococcus granulosus nervana 2 0.0045 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0163
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0323 0.1377 0.1377
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0003 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0058 0.0058
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0022 0.0003 0.0003
Echinococcus granulosus serine/threonine protein kinase 0.0059 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0036 0.0068 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0288
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.023
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0277 0.2008
Loa Loa (eye worm) plexin A 0.0045 0.0108 0.0223
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.003 0.004 0.0094
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Echinococcus multilocularis cyclin dependent kinase 5 0.0103 0.0374 0.0374
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0068 0.5
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0277 0.2008
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus tyrosine protein kinase Blk 0.0107 0.0392 0.0392
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0032 0.0049 0.01
Echinococcus multilocularis beta adrenergic receptor kinase 0.003 0.0041 0.0041
Trypanosoma cruzi cdc2-related kinase 1 0.0103 0.0374 0.2503
Schistosoma mansoni tyrosine kinase 0.0811 0.3613 0.3613
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Brugia malayi serine/threonine protein kinase 6 0.0256 0.1074 0.2545
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0003 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0103 0.0374 0.2503
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0022 0.0001 0.0001
Brugia malayi Trypsin family protein 0.0039 0.0079 0.0187
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0087
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0033 0.0307
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0049 0.0353
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0124 0.0294
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0003 0.0003
Brugia malayi nuclear receptor NHR-88 0.0022 0.0003 0.0006
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.004 0.004
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0374 0.2719
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0163
Onchocerca volvulus 0.0022 0.0003 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0037 0.0087
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0054 0.015 0.0825
Loa Loa (eye worm) hypothetical protein 0.0043 0.0097 0.02
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0124 0.0293
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0058 0.0058
Schistosoma mansoni polycystin 1-related 0.0022 0.0000090787 0.0000090787
Schistosoma mansoni tyrosine-protein kinase fps85d 0.003 0.004 0.004
Echinococcus granulosus tar DNA binding protein 0.0062 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0094 0.0333 0.0686
Loa Loa (eye worm) hypothetical protein 0.0114 0.0424 0.0873
Brugia malayi Niemann-Pick C1 protein precursor 0.0202 0.0824 0.1951
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.005 0.0131 0.0269
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0256 0.1074 0.1074
Echinococcus granulosus NCK adaptor protein 0.0025 0.0015 0.0015
Echinococcus granulosus defective proboscis extension response 0.0075 0.0247 0.0247
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0029 0.0033 0.0307
Schistosoma mansoni cpg binding protein 0.0028 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0288
Echinococcus granulosus epidermal growth factor receptor 0.0639 0.2826 0.2826
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0277 0.2008
Giardia lamblia Kinase 0.003 0.004 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0079 0.0188
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0003 0.0003
Schistosoma mansoni plexin 0.0038 0.0076 0.0076
Echinococcus granulosus enteropeptidase 0.0039 0.0079 0.0079
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.006 0.0178 0.0366
Loa Loa (eye worm) hypothetical protein 0.0114 0.0424 0.0873
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.003 0.004 0.004
Echinococcus multilocularis RUN 0.0022 0.0000090787 0.0000090787
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0081 0.0589
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0589
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0277 0.2008
Onchocerca volvulus 0.0043 0.0097 0.0298
Echinococcus granulosus cyclins 0.0039 0.0081 0.0081
Plasmodium vivax protein kinase Crk2 0.0103 0.0374 0.3485
Loa Loa (eye worm) hypothetical protein 0.0034 0.0058 0.0119
Loa Loa (eye worm) hypothetical protein 0.0075 0.0247 0.0507
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.1084 0.486 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0032 0.0049 0.0049
Echinococcus granulosus expressed protein 0.0419 0.1816 0.1816
Echinococcus multilocularis neuroglian 0.0051 0.0137 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0079 0.0188
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.004
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0068 0.0014
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis serine:threonine protein kinase N2 0.0032 0.0049 0.0049
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0000090787 0.0000090787
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.003 0.004 0.004
Brugia malayi RNA binding protein 0.0062 0.0184 0.0436
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0049 0.0049
Onchocerca volvulus 0.003 0.004 0.0122
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Brugia malayi Heparan sulfate 0.0022 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.01
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0039 0.0081 0.031
Loa Loa (eye worm) hypothetical protein 0.0049 0.0124 0.0255
Echinococcus granulosus Niemann Pick C1 protein 0.0202 0.0824 0.0824
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1074 0.7801
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0003 0.0006
Toxoplasma gondii STE kinase 0.003 0.004 0.0063
Echinococcus multilocularis neuroglian 0.0092 0.0325 0.0325
Echinococcus granulosus neuroglian 0.0092 0.0325 0.0325
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.005 0.0131 0.0093
Echinococcus multilocularis twitchin 0.0026 0.0021 0.0021
Plasmodium falciparum protein kinase, putative 0.003 0.004 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0041 0.0041
Echinococcus multilocularis tyrosine protein kinase shark 0.0043 0.0097 0.0097
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.003 0.004 0.0122
Trypanosoma brucei protein kinase, putative 0.0039 0.0081 0.0308
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0079 0.0188
Brugia malayi plexin A 0.0045 0.0108 0.0257
Echinococcus granulosus activated cdc42 kinase 1 0.003 0.004 0.004
Onchocerca volvulus 0.0043 0.0097 0.0298
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis ephrin type A receptor 4 A 0.018 0.0723 0.0723
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0022 0.0001 0.0001
Giardia lamblia Kinase, AGC PKA 0.0054 0.015 0.087
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.011
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0032 0.0049 0.0049
Onchocerca volvulus 0.0034 0.0058 0.0177
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0041 0.0041
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0082
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0119 0.0448 0.0448
Echinococcus multilocularis cyclins 0.0039 0.0081 0.0081
Onchocerca volvulus 0.003 0.004 0.0122
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0162
Echinococcus multilocularis protein kinase c epsilon type 0.0032 0.0049 0.0049
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0081 0.0308
Loa Loa (eye worm) hypothetical protein 0.0036 0.0068 0.0139
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0082
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0103 0.0374 0.077
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0001 0.0003
Echinococcus granulosus protein tyrosine kinase 0.0586 0.2584 0.2584
Brugia malayi basement membrane proteoglycan precursor 0.0022 0.0001 0.0003
Trypanosoma brucei mitotic cyclin 6 0.0039 0.0081 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0003 0.0005
Echinococcus granulosus Immunoglobulin 0.0022 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0154 0.0154
Onchocerca volvulus 0.0051 0.0136 0.0416
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0007
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.023
Echinococcus granulosus sterol regulatory element binding protein 0.0086 0.0297 0.0297
Schistosoma mansoni tyrosine kinase 0.0055 0.0153 0.0153
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0589
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0049 0.0353
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0037 0.0072 0.0521
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0184 0.0184
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0003 0.0003
Echinococcus multilocularis nervana 2 0.0045 0.0109 0.0109
Echinococcus granulosus twitchin 0.0101 0.0366 0.0366
Brugia malayi Protein kinase domain containing protein 0.0043 0.0097 0.023
Echinococcus granulosus c src tyrosine kinase 0.0055 0.0153 0.0153
Loa Loa (eye worm) trypsin family protein 0.0039 0.0079 0.0162
Brugia malayi ecdysteroid receptor 0.0022 0.0003 0.0006
Schistosoma mansoni roundabout 0.0039 0.0079 0.0079
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0032 0.0049 0.0049
Echinococcus granulosus protein kinase 0.003 0.004 0.004
Echinococcus granulosus cyclins 0.0039 0.0081 0.0081
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0131 0.0501 0.3447
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Brugia malayi serine/threonine-protein kinase plk-2 0.0323 0.1377 0.3262
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0069 0.0503
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0162
Echinococcus granulosus tyrosine protein kinase Lyn 0.0128 0.0489 0.0489
Onchocerca volvulus 0.003 0.004 0.0122
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0082
Echinococcus granulosus roundabout 2 0.0051 0.0137 0.0137
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0255 0.1068 0.1068
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0323 0.1377 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.003 0.004 0.004
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0075 0.0247 0.0247
Echinococcus multilocularis plexin a4 0.0045 0.0108 0.0108
Echinococcus granulosus protein kinase c epsilon type 0.0032 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0049
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0288
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0124 0.0083
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0119 0.0448 0.0448
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Onchocerca volvulus 0.003 0.0037 0.0113
Echinococcus granulosus Protein kinase C brain isozyme 0.0032 0.0049 0.0049
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0288
Leishmania major casein kinase II, putative 0.0157 0.0618 0.4325
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.004 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0157 0.0618 0.4488
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.003 0.004 0.004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1074 0.7801
Onchocerca volvulus 0.0043 0.0097 0.0298
Echinococcus granulosus Glutaredoxin protein 5 0.0045 0.0109 0.0109
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0003 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Echinococcus multilocularis NCK adaptor protein 0.0025 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0147 0.0575 0.1184
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.003 0.004 0.004
Entamoeba histolytica casein kinase, putative 0.0157 0.0618 0.4488
Brugia malayi Protein kinase domain containing protein 0.0082 0.0277 0.0655
Echinococcus granulosus cyclin B 0.0039 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0003 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0131 0.0501 0.0501
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.0374 0.2719
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Plasmodium falciparum cyclin 0.0039 0.0081 0.0754
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0003 0.0006
Onchocerca volvulus 0.003 0.004 0.0122
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0033 0.024
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis cyclin D, putative 0.0039 0.0081 0.0589
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.005 0.0131 0.0131
Brugia malayi SRC-1 0.0119 0.0448 0.1061
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0256 0.1074 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.005 0.0131 0.011
Giardia lamblia Aurora kinase 0.0256 0.1074 0.7747
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0824 0.367 0.367
Echinococcus multilocularis roundabout 2 0.0127 0.0481 0.0481
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0058 0.0138
Brugia malayi hypothetical protein 0.003 0.004 0.0094
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0077 0.0254 0.0254
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0153 0.115
Schistosoma mansoni cpg binding protein 0.003 0.0039 0.0039
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Entamoeba histolytica ankyrin repeat protein 0.003 0.004 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0049 0.0353
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.086 0.3835 0.3835
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0003 0.0006
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0131 0.0501 0.0674
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.003 0.004 0.004
Brugia malayi Protein kinase domain containing protein 0.0811 0.3613 0.8558
Loa Loa (eye worm) hypothetical protein 0.046 0.2008 0.413
Loa Loa (eye worm) hypothetical protein 0.0121 0.0453 0.0933
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0032 0.0049 0.01
Schistosoma mansoni tyrosine kinase 0.0609 0.2688 0.2688
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0047 0.0118 0.0118
Brugia malayi protein kinase C II. 0.0032 0.0049 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0076
Loa Loa (eye worm) cyclin domain-containing protein 0.0039 0.0081 0.0167
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0184 0.0379
Echinococcus multilocularis geminin 0.0165 0.0657 0.0657
Echinococcus granulosus growth factor receptor bound protein 2 0.0025 0.0015 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0184 0.0184
Entamoeba histolytica protein kinase domain containing protein 0.0039 0.0081 0.0587
Loa Loa (eye worm) hypothetical protein 0.0049 0.0124 0.0254
Echinococcus granulosus titin 0.0039 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0003 0.0006
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1468 0.6615 1
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis retinal guanylyl cyclase 2 0.003 0.004 0.004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Onchocerca volvulus 0.003 0.004 0.0122
Echinococcus granulosus tyrosine protein kinase shark 0.0043 0.0097 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0154 0.0154
Onchocerca volvulus 0.0039 0.0079 0.0242
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0003 0.0003
Brugia malayi hypothetical protein 0.0251 0.1049 0.2484
Entamoeba histolytica serine/threonine protein kinase, putative 0.0323 0.1377 1
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0412 0.2996
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.003 0.004 0.0094
Entamoeba histolytica protein kinase, putative 0.0095 0.0334 0.2429
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0316 0.1345 0.2767
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0051 0.0137 0.0137
Giardia lamblia Cyclin A 0.0039 0.0081 0.0357
Echinococcus multilocularis netrin receptor unc 5 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0081 0.0167
Loa Loa (eye worm) hypothetical protein 0.0036 0.0068 0.0139
Loa Loa (eye worm) TK/ROR protein kinase 0.0047 0.0118 0.0242
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1377 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.0001 0.0001
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0039 0.0079 0.0079
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0003 0.0003
Echinococcus multilocularis serine threonine protein kinase 0.0032 0.0049 0.0049
Echinococcus multilocularis cyclins 0.0039 0.0081 0.0081
Schistosoma mansoni netrin receptor unc5 0.0022 0.0001 0.0001
Schistosoma mansoni basigin related 0.0022 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0003 0.0005
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0157 0.0618 0.5753
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0032 0.0049 0.01
Schistosoma mansoni loxhd1 0.0022 0.0000090787 0.0000090787
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0618 0.4488
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.003 0.0041 0.0085
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0003 0.0003
Plasmodium falciparum cysteine repeat modular protein 4 0.0029 0.0033 0.0307
Brugia malayi hypothetical protein 0.0147 0.0575 0.1363
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0162
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.005 0.0131 0.0727
Echinococcus multilocularis nervana 2 0.0045 0.0109 0.0109
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.003 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis natriuretic peptide receptor 1 0.003 0.004 0.004
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0039 0.0081 0.0081
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0137 0.0323
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0082
Schistosoma mansoni cell adhesion molecule 0.0039 0.0079 0.0079
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Onchocerca volvulus 0.0049 0.0124 0.0379
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.005 0.0131 0.0011
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.003 0.0037 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0003 0.0006
Entamoeba histolytica cysteine-rich surface protein, putative 0.0029 0.0033 0.024
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Plasmodium vivax tyrosine kinase-like protein, putative 0.003 0.004 0.0369
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0323 0.1377 0.1377
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0119 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0036 0.0068 0.0139
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0051 0.0137 0.0137
Trichomonas vaginalis cyclin B3, putative 0.0039 0.0081 0.0589
Loa Loa (eye worm) AGC/PKN protein kinase 0.0032 0.0049 0.01
Schistosoma mansoni tyrosine kinase 0.0811 0.3613 0.3613
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.004 0.0082
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0124 0.0254
Brugia malayi SH2 domain containing protein 0.0043 0.0097 0.023
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Echinococcus granulosus serine threonine protein kinase nrc 0.0054 0.015 0.015
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0055 0.0153 0.0153
Brugia malayi Trypsin-like protease protein 5 0.0039 0.0079 0.0187
Echinococcus multilocularis serine:threonine protein kinase 38 0.0032 0.0049 0.0049
Schistosoma mansoni myosin-binding protein-related 0.003 0.0037 0.0037
Schistosoma mansoni titin 0.0039 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0068
Echinococcus multilocularis lachesin 0.0039 0.0079 0.0079
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Trypanosoma brucei polo-like protein kinase 0.0323 0.1377 1
Echinococcus granulosus RUN 0.0022 0.0000090787 0.0000090787
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0003 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.004
Echinococcus multilocularis Immunoglobulin 0.0075 0.0247 0.0247
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0277 0.2008
Brugia malayi Protein kinase domain containing protein 0.0032 0.0049 0.0115
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Echinococcus multilocularis peroxidasin 0.0039 0.0079 0.0079
Plasmodium vivax tyrosine kinase-like protein, putative 0.003 0.004 0.0369
Brugia malayi Tyrosine-protein kinase abl-1 0.0055 0.0153 0.0362
Schistosoma mansoni growth factor receptor-bound protein 0.0025 0.0015 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0049
Onchocerca volvulus 0.0039 0.0079 0.0242
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.005 0.0131 0.031
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.0304 0.0719
Entamoeba histolytica ankyrin repeat protein 0.003 0.004 0.0288
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus integrin linked protein kinase 0.003 0.004 0.004
Echinococcus granulosus netrin receptor unc 5 0.0022 0.0001 0.0001
Echinococcus multilocularis roundabout 2 0.0051 0.0137 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Giardia lamblia G2/mitotic-specific cyclin B 0.0039 0.0081 0.0357
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0124 0.0083
Onchocerca volvulus 0.0039 0.0078 0.0239
Echinococcus granulosus kinase suppressor of Ras 1 0.003 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Brugia malayi CXXC zinc finger family protein 0.0028 0.0031 0.0074
Onchocerca volvulus 0.0043 0.0097 0.0298
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0162
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0814 0.3624 0.7456
Brugia malayi cell division control protein 2 homolog 0.0103 0.0374 0.0887
Schistosoma mansoni ephrin receptor 0.0151 0.0591 0.0591
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Echinococcus granulosus muscleblind protein 0.046 0.2008 0.2008
Echinococcus multilocularis serine:threonine protein kinase N2 0.0032 0.0049 0.0049
Schistosoma mansoni cell adhesion molecule 0.0051 0.0137 0.0137
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Entamoeba histolytica protein kinase, putative 0.0038 0.0074 0.0539
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0154 0.0154
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0003 0.0005
Brugia malayi CHE-14 protein 0.0086 0.0297 0.0704
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.003 0.004 0.0082
Echinococcus multilocularis kinase suppressor of Ras 1 0.003 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0088 0.0304 0.0625
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Mycobacterium ulcerans hypothetical protein 0.0039 0.0079 0.0017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0068
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0039 0.0081 0.0308
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Plasmodium falciparum protein kinase, putative 0.0039 0.0081 0.0752
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0054 0.0127
Mycobacterium ulcerans hypothetical protein 0.0049 0.0124 0.0083
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0374 0.0374
Echinococcus multilocularis rac serine:threonine kinase 0.0059 0.0171 0.0171
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Onchocerca volvulus 0.0029 0.0033 0.0101
Echinococcus multilocularis tyrosine kinase 0.0043 0.0097 0.0097
Echinococcus granulosus tyrosine protein kinase 0.003 0.004 0.004
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0039 0.0079 0.0079
Schistosoma mansoni tyrosine kinase 0.0586 0.2584 0.2584
Schistosoma mansoni tyrosine kinase 0.0055 0.0153 0.0153
Entamoeba histolytica cysteine surface protein, putative 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Onchocerca volvulus 0.0039 0.0079 0.0242
Schistosoma mansoni hypothetical protein 0.0039 0.0079 0.0079
Loa Loa (eye worm) SRC-1 0.0119 0.0448 0.0921
Brugia malayi C-terminal src kinase protein 1 0.003 0.004 0.0094
Plasmodium falciparum protein kinase 5 0.0103 0.0374 0.3485
Giardia lamblia Kinase, CMGC CK2 0.0157 0.0618 0.4352
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0119 0.0448 0.0448
Brugia malayi basement membrane proteoglycan 0.0022 0.0001 0.0003
Loa Loa (eye worm) TK/ACK protein kinase 0.003 0.004 0.0082
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.005 0.0131 0.1217
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Brugia malayi Cyclin, N-terminal domain containing protein 0.0039 0.0081 0.0192
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0001
Loa Loa (eye worm) AGC/AKT protein kinase 0.0082 0.0277 0.0569
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0277 0.2008
Toxoplasma gondii protein kinase 0.003 0.004 0.0063
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0107 0.0392 0.0392
Brugia malayi hypothetical protein 0.003 0.004 0.0094
Schistosoma mansoni protein kinase 0.0213 0.0874 0.0874
Entamoeba histolytica protein kinase, putative 0.0256 0.1074 0.7801
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0157 0.0618 0.1272
Trichomonas vaginalis cyclin D, putative 0.0039 0.0081 0.0589
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0003 0.0006
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.003 0.004 0.0082
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni hypothetical protein 0.0165 0.0657 0.0657
Brugia malayi bone morphogenetic protein type 1 receptor 0.003 0.004 0.0094
Trypanosoma cruzi polo-like protein kinase, putative 0.0323 0.1377 1
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0256 0.1074 0.7801
Loa Loa (eye worm) hypothetical protein 0.0038 0.0076 0.0157
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0041 0.0041
Plasmodium falciparum tyrosine kinase-like protein 0.003 0.004 0.0369
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.003 0.004 0.0082
Leishmania major cyclin 0.0039 0.0081 0.031
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0000090787 0.0000090787
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0058 0.0058
Echinococcus granulosus nephrin 0.003 0.0037 0.0037
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Brugia malayi Tyrosine-protein kinase PR2 0.003 0.004 0.0094
Echinococcus multilocularis aurora kinase A 0.0256 0.1074 0.1074
Echinococcus granulosus glycoprotein Antigen 5 0.0039 0.0079 0.0079
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0029 0.0033 0.0307
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Onchocerca volvulus 0.003 0.004 0.0122
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0001 0.0003
Schistosoma mansoni src-type protein tyrosine kinase-related 0.003 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis activated cdc42 kinase 1 0.003 0.004 0.004
Plasmodium falciparum cysteine repeat modular protein 2 0.0029 0.0033 0.0307
Brugia malayi Prion-like- 0.0039 0.0079 0.0188
Echinococcus multilocularis tyrosine protein kinase otk 0.0039 0.0079 0.0079
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0182 0.0182
Loa Loa (eye worm) TK/EPH protein kinase 0.0184 0.0743 0.1528
Giardia lamblia Kinase, CMGC CDK 0.0103 0.0374 0.254
Echinococcus granulosus tyrosine protein kinase Btk29A 0.003 0.004 0.004
Schistosoma mansoni basigin related 0.0022 0.0001 0.0001
Entamoeba histolytica tyrosin kinase, putative 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0082
Loa Loa (eye worm) AGC/NDR protein kinase 0.0032 0.0049 0.01
Entamoeba histolytica hypothetical protein, conserved 0.003 0.004 0.0288
Echinococcus multilocularis activin receptor type 0.0039 0.0081 0.0081
Brugia malayi hypothetical protein 0.0088 0.0304 0.0719
Echinococcus granulosus protein kinase C gamma type 0.0032 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0049
Plasmodium falciparum cysteine repeat modular protein 1 0.0029 0.0033 0.0307
Loa Loa (eye worm) TK/FAK protein kinase 0.0593 0.2614 0.5379
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0618 0.4488
Schistosoma mansoni netrin receptor unc5 0.0022 0.0001 0.0001
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.004 0.004
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0124 0.0099
Echinococcus multilocularis Immunoglobulin 0.0075 0.0247 0.0247
Echinococcus granulosus tyrosine protein kinase Src42A 0.0077 0.0254 0.0254
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0154 0.0154
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1377 1
Schistosoma mansoni serine/threonine protein kinase 0.003 0.004 0.004
Loa Loa (eye worm) TK/EGFR protein kinase 0.0944 0.4221 0.8685
Schistosoma mansoni hypothetical protein 0.003 0.004 0.004
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Echinococcus multilocularis cyclin B 0.0039 0.0081 0.0081
Echinococcus granulosus Protein patched homolog 1 0.0086 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0003
Schistosoma mansoni cell adhesion molecule 0.0022 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0047 0.0118 0.0118
Echinococcus granulosus endonuclease reverse transcriptase 0.0029 0.0033 0.0033
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0184 0.0436
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0039 0.0079 0.0079
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0058 0.0235
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0039 0.0081 0.0081
Loa Loa (eye worm) TK/ABL protein kinase 0.0043 0.0097 0.02
Schistosoma mansoni regulator of G protein signaling 0.0024 0.001 0.001
Echinococcus granulosus insulin receptor 0.0811 0.3613 0.3613
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Onchocerca volvulus 0.0038 0.0076 0.0234
Onchocerca volvulus 0.0039 0.0079 0.0242
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0163
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0068
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0051 0.0137 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1074 0.7801
Schistosoma mansoni titin 0.0039 0.0079 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0049
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0034 0.0058 0.0058
Echinococcus multilocularis protein patched 0.0086 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0297 0.2159
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.003 0.004 0.0082
Loa Loa (eye worm) hypothetical protein 0.0088 0.0304 0.0625
Brugia malayi integrin-linked kinase 0.003 0.004 0.0094
Entamoeba histolytica serine/threonine kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0103 0.0374 0.077
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0119 0.0448 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0003 0.0005
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0029 0.0033 0.0307
Schistosoma mansoni hypothetical protein 0.0083 0.0283 0.0283
Schistosoma mansoni tyrosine kinase 0.0609 0.2688 0.2688
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0031 0.0064
Echinococcus granulosus cyclins 0.0039 0.0081 0.0081
Echinococcus granulosus titin 0.0039 0.0078 0.0078
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0003 0.0003
Entamoeba histolytica protein kinase , putative 0.0256 0.1074 0.7801
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0124 0.0293
Loa Loa (eye worm) hypothetical protein 0.0075 0.0247 0.0507
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0003 0.0006
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.005 0.0131 0.095
Echinococcus granulosus hemicentin 1 0.0039 0.0079 0.0079
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus multilocularis transfer RNA-Thr 0.003 0.004 0.004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0154 0.0154
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0051 0.0137 0.0137
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0078 0.0185
Schistosoma mansoni septate junction protein 0.0039 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0032 0.0049 0.0049
Loa Loa (eye worm) TK/ALK protein kinase 0.003 0.004 0.0082
Schistosoma mansoni tyrosine kinase 0.0043 0.0097 0.0097
Leishmania major protein kinase, putative 0.0039 0.0081 0.0308
Echinococcus multilocularis cyclin dependent kinase 1 0.0103 0.0374 0.0374
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0068
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni cell adhesion molecule 0.003 0.0037 0.0037
Entamoeba histolytica protein kinase 2, putative 0.0054 0.015 0.109
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0032 0.0049 0.0049
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.003 0.004 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0097 0.0346 0.0712
Brugia malayi hypothetical protein 0.0039 0.0079 0.0187
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Schistosoma mansoni cpg binding protein 0.003 0.0039 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0618 0.4488
Entamoeba histolytica protein kinase, putative 0.0032 0.0049 0.0353
Entamoeba histolytica protein kinase domain containing protein 0.0256 0.1074 0.7801
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0131 0.0501 0.0501
Onchocerca volvulus 0.0039 0.0081 0.0249
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.005 0.0131 0.0131
Loa Loa (eye worm) TK/FER protein kinase 0.003 0.004 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0078 0.0078
Schistosoma mansoni nephrin related 0.0022 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0082 0.0277 0.2008
Schistosoma mansoni protein kinase 0.0157 0.0618 0.0618
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0003 0.0003
Echinococcus multilocularis protein dispatched 1 0.0099 0.0353 0.0353
Echinococcus granulosus serine:threonine protein kinase N2 0.0032 0.0049 0.0049
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Echinococcus granulosus epidermal growth factor receptor 0.0944 0.4221 0.4221
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Plasmodium falciparum serine/threonine protein kinase, putative 0.0256 0.1074 1
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0288
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Schistosoma mansoni hypothetical protein 0.0404 0.1748 0.1748
Echinococcus multilocularis Immunoglobulin 0.0022 0.0001 0.0001
Echinococcus multilocularis hemicentin 1 0.0039 0.0079 0.0079
Onchocerca volvulus 0.003 0.004 0.0122
Loa Loa (eye worm) hypothetical protein 0.0049 0.0124 0.0254
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0589
Echinococcus multilocularis protein kinase c iota type 0.0032 0.0049 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0003 0.0003
Brugia malayi GCC2 and GCC3 family protein 0.0029 0.0033 0.0078
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.003 0.004 0.004
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0618 0.4488
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.003 0.004 0.004
Echinococcus granulosus tyrosine protein kinase csk 0.003 0.004 0.004
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0039 0.0079 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0051 0.0137 0.0323
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus Niemann Pick C1 protein 0.0288 0.1219 0.1219
Echinococcus multilocularis tyrosine protein kinase 0.003 0.004 0.004
Leishmania major protein kinase, putative 0.0256 0.1074 0.7736
Echinococcus granulosus tyrosine protein kinase Src64B 0.0119 0.0448 0.0448
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0003 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0079 0.0079
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.0001 0.0003
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0323 0.1377 0.2833
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0075 0.0247 0.0247
Loa Loa (eye worm) RNA binding protein 0.0062 0.0184 0.0379
Trypanosoma cruzi cdc2-related kinase 3 0.0103 0.0374 0.2503
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Brugia malayi nuclear hormone receptor 0.0022 0.0003 0.0006
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Trypanosoma cruzi casein kinase II, putative 0.0157 0.0618 0.4325
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0589
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0039 0.0081 0.0459
Echinococcus granulosus retinal guanylyl cyclase 2 0.003 0.004 0.004
Echinococcus granulosus cyclin dependent kinase 0.0103 0.0374 0.0374
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0049 0.0049
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0015 0.0035
Brugia malayi Hr1 repeat family protein 0.0032 0.0049 0.0115
Schistosoma mansoni protein kinase 0.0039 0.0081 0.0081
Loa Loa (eye worm) TK/INSR protein kinase 0.0811 0.3613 0.7433
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni plexin 0.0022 0.0003 0.0003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0184 0.0379
Brugia malayi ephrin receptor 1 precursor 0.0087 0.03 0.071
Loa Loa (eye worm) TK protein kinase 0.003 0.004 0.0082
Echinococcus granulosus lachesin 0.0039 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0051 0.0136 0.0136
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Echinococcus multilocularis expressed protein 0.0419 0.1816 0.1816
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0003
Echinococcus granulosus transmembrane protease serine 3 0.0039 0.0079 0.0079
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0097 0.02
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0003 0.0006
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.1377 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0086 0.0297 0.0612
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.003 0.004 0.004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0154 0.0154
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.005 0.0131 0.0681
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0003 0.0006
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0033 0.0307
Schistosoma mansoni tyrosine kinase 0.0043 0.0097 0.0097
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Trichomonas vaginalis CMGC family protein kinase 0.0157 0.0618 0.4488
Echinococcus multilocularis integrin linked protein kinase 0.003 0.004 0.004
Trichomonas vaginalis AGC family protein kinase 0.0256 0.1074 0.7801
Plasmodium falciparum tyrosine kinase-like protein 0.003 0.004 0.0369
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.003 0.004 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.1074 0.1074
Brugia malayi Trypsin family protein 0.0039 0.0079 0.0187
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0075 0.0247 0.0247
Echinococcus granulosus receptor type guanylyl cyclase 0.003 0.004 0.004
Brugia malayi Protein kinase domain containing protein 0.0103 0.0374 0.0887
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.003 0.004 0.0288
Loa Loa (eye worm) CAMK protein kinase 0.0039 0.0078 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.003 0.004 0.0288
Schistosoma mansoni tyrosine protein kinase 0.003 0.004 0.004
Schistosoma mansoni protein tyrosine kinase 0.003 0.004 0.004
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Brugia malayi Immunoglobulin domain containing protein 0.0022 0.0001 0.0003
Echinococcus granulosus geminin 0.0165 0.0657 0.0657
Schistosoma mansoni hypothetical protein 0.0022 0.0001 0.0001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0202 0.0824 0.5981
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.003 0.004 0.0288
Onchocerca volvulus 0.0039 0.0079 0.0242
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0163
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0097 0.0346 0.0346
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Plasmodium vivax unspecified product 0.0157 0.0618 0.5753
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Trichomonas vaginalis cyclins, putative 0.0039 0.0081 0.0589
Echinococcus multilocularis Niemann Pick C1 protein 0.0202 0.0824 0.0824
Loa Loa (eye worm) hypothetical protein 0.0202 0.0824 0.1694
Loa Loa (eye worm) TK/CSK protein kinase 0.003 0.004 0.0082
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.003 0.004 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0124 0.0099
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.003 0.0037 0.0037
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0025 0.0015 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0184 0.0184
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Trichomonas vaginalis protein kinase atn1, putative 0.003 0.004 0.0288
Echinococcus granulosus ephrin type A receptor 4 A 0.018 0.0723 0.0723
Loa Loa (eye worm) protein kinase domain-containing protein 0.003 0.004 0.0082
Brugia malayi hypothetical protein 0.0022 0.0001 0.0003
Entamoeba histolytica cyclin, putative 0.0039 0.0081 0.0589
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.003 0.004 0.0288
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni septate junction protein 0.0022 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase csk 0.003 0.004 0.004
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Echinococcus granulosus cyclin dependent kinase 5 0.0103 0.0374 0.0374
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0054 0.015 0.015
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0043 0.0097 0.0705
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.005 0.0131 0.1217
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0003 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0374 0.2719
Echinococcus granulosus tyrosine protein kinase otk 0.0039 0.0079 0.0079
Trypanosoma brucei cdc2-related kinase 1 0.0103 0.0374 0.2503
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.003 0.004 0.004
Onchocerca volvulus 0.0686 0.3041 0.9337
Brugia malayi Protein kinase domain containing protein 0.003 0.004 0.0094
Trypanosoma brucei rac serine-threonine kinase, putative 0.0082 0.0277 0.1771
Echinococcus multilocularis Niemann Pick C1 protein 0.0288 0.1219 0.1219
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.005 0.0131 0.0681
Schistosoma mansoni hypothetical protein 0.0029 0.0033 0.0033
Brugia malayi Peroxidasin 0.0039 0.0079 0.0188
Loa Loa (eye worm) hypothetical protein 0.0051 0.0137 0.0281
Schistosoma mansoni protein kinase 0.003 0.004 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0124 0.0083
Loa Loa (eye worm) hypothetical protein 0.0069 0.0219 0.045
Brugia malayi protein-tyrosine kinase 0.0107 0.0392 0.0928
Echinococcus multilocularis tyrosine kinase 0.003 0.004 0.004
Onchocerca volvulus 0.003 0.0037 0.0113
Echinococcus granulosus tyrosine protein kinase Srms 0.0043 0.0097 0.0097
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0058 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0021 0.0021
Schistosoma mansoni cell adhesion molecule 0.0051 0.0137 0.0137
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0124 0.0294
Toxoplasma gondii CMGC kinase, CK2 family 0.0157 0.0618 0.5618
Echinococcus multilocularis hemicentin 1 0.0039 0.0079 0.0079
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.003 0.004 0.0063
Brugia malayi Casein kinase II, alpha chain 0.0157 0.0618 0.1464
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.003 0.004 0.004
Echinococcus granulosus natriuretic peptide receptor 1 0.003 0.004 0.004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0003 0.0003
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.0001 0.0001
Loa Loa (eye worm) TK/DDR protein kinase 0.003 0.004 0.0082
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0058 0.0058
Schistosoma mansoni survival motor neuron protein 0.0051 0.0136 0.0136
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0045 0.0109 0.0109
Entamoeba histolytica protein kinase domain containing protein 0.003 0.004 0.0288
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0163
Echinococcus granulosus cpg binding protein 0.003 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0005
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0022 0.0001 0.0001
Schistosoma mansoni neuroglian 0.0051 0.0137 0.0137
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0055 0.0153 0.0153
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.003 0.004 0.0288
Schistosoma mansoni protein kinase 0.0213 0.0874 0.0874
Echinococcus multilocularis casein kinase ii subunit alpha 0.0157 0.0618 0.0618
Onchocerca volvulus 0.0029 0.0033 0.0101
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0162
Schistosoma mansoni tyrosine kinase 0.0639 0.2826 0.2826
Brugia malayi SH2 domain containing protein 0.0043 0.0097 0.023
Echinococcus granulosus tyrosine protein kinase ABL1 0.0043 0.0097 0.0097
Brugia malayi Sex muscle abnormal protein 5 0.0025 0.0015 0.0035
Entamoeba histolytica tyrosine kinase, putative 0.003 0.004 0.0288
Entamoeba histolytica cyclin family protein 0.0039 0.0081 0.0589
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0039 0.0081 0.0167
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0136 0.0321
Brugia malayi Probable tyrosine-protein kinase kin-31 0.003 0.004 0.0094
Entamoeba histolytica protein kinase, putative 0.003 0.004 0.0288
Giardia lamblia Kinase, NEK 0.003 0.004 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0003 0.0006
Echinococcus multilocularis Glutaredoxin protein 5 0.0045 0.0109 0.0109
Onchocerca volvulus 0.0028 0.0031 0.0096
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0032 0.0049 0.0049
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0025 0.0015 0.0015
Brugia malayi serine/threonine kinase 12 0.0256 0.1074 0.2545
Loa Loa (eye worm) hypothetical protein 0.003 0.004 0.0082
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0184 0.0184
Schistosoma mansoni tyrosine kinase 0.003 0.004 0.004
Echinococcus multilocularis Mastin 0.0039 0.0079 0.0079
Schistosoma mansoni lipoxygenase 0.0022 0.0000090787 0.0000090787
Echinococcus multilocularis insulin receptor 0.0811 0.3613 0.3613
Entamoeba histolytica hypothetical protein 0.003 0.004 0.0288
Echinococcus multilocularis Immunoglobulin subtype 0.0022 0.0001 0.0001
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0003 0.0003
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0213 0.0874 0.0874
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.003 0.004 0.004
Trypanosoma cruzi aurora B kinase, putative 0.0256 0.1074 0.7736
Echinococcus granulosus low density lipoprotein receptor ldl 0.0022 0.0001 0.0001

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.9953 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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