Detailed information for compound 1499847

Basic information

Technical information
  • TDR Targets ID: 1499847
  • Name: N-tert-butyl-2-[3-cyano-6-methyl-4-(trifluoro methyl)pyridin-2-yl]sulfanylacetamide
  • MW: 331.357 | Formula: C14H16F3N3OS
  • H donors: 1 H acceptors: 3 LogP: 3.03 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1c(SCC(=O)NC(C)(C)C)nc(cc1C(F)(F)F)C
  • InChi: 1S/C14H16F3N3OS/c1-8-5-10(14(15,16)17)9(6-18)12(19-8)22-7-11(21)20-13(2,3)4/h5H,7H2,1-4H3,(H,20,21)
  • InChiKey: JIGREOAFYCOJOD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-tert-butyl-2-[[3-cyano-6-methyl-4-(trifluoromethyl)-2-pyridyl]sulfanyl]acetamide
  • N-tert-butyl-2-[[3-cyano-6-methyl-4-(trifluoromethyl)-2-pyridyl]thio]acetamide
  • N-tert-butyl-2-[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-ethanamide
  • ZINC00139447
  • A0162/0007241
  • MLS000092387
  • N-(tert-butyl)-2-{[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]thio}acetamide
  • SMR000027464

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tubulin gamma 1 chain 0.0121 0.225 0.2492
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0266 1
Leishmania major UDP-galactopyranose mutase 0.0021 0.0251 0.0497
Echinococcus granulosus netrin receptor unc 5 0.0086 0.1552 0.1719
Onchocerca volvulus 0.0148 0.2791 0.2778
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0266 0.0242
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0021 0.0251 0.0227
Trypanosoma brucei unspecified product 0.0019 0.0218 0.042
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0251 0.0531
Brugia malayi hypothetical protein 0.0021 0.0251 0.0251
Leishmania major ATP-binding cassette protein subfamily G, member 1, putative 0.001 0.0043 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0251 0.0251
Trypanosoma brucei ATP-binding cassette protein subfamily G 0.001 0.0043 0.0007
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0021 0.0251 0.2625
Brugia malayi Death domain containing protein 0.0086 0.1552 0.1552
Giardia lamblia Kinase, PLK 0.0093 0.1685 0.15
Leishmania major delta tubulin, putative 0.0053 0.0887 0.1995
Loa Loa (eye worm) hypothetical protein 0.0015 0.0149 0.0149
Trypanosoma brucei ATP-binding cassette protein, putative 0.0061 0.1049 0.2376
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0018 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0218 0.0455
Brugia malayi RNA binding protein 0.0064 0.1105 0.1105
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0251 0.0244
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0053 0.0887 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0053 0.0887 0.0756
Entamoeba histolytica tubulin family protein 0.0224 0.4288 0.4274
Loa Loa (eye worm) tubulin alpha 2 0.0048 0.0795 0.0795
Onchocerca volvulus 0.0069 0.1204 0.1188
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0266 0.0294
Trichomonas vaginalis tubulin epsilon chain, putative 0.0224 0.4288 0.4206
Trypanosoma cruzi epsilon tubulin, putative 0.0121 0.225 0.5221
Echinococcus granulosus dna polymerase kappa 0.0019 0.0218 0.0241
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0304 0.0623
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0304 0.0281
Schistosoma mansoni tubulin subunit alpha 0.0169 0.3204 0.3549
Leishmania major beta tubulin 0.0224 0.4288 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0224 0.4288 0.4749
Trichomonas vaginalis tubulin beta chain, putative 0.0169 0.3204 0.3107
Loa Loa (eye worm) BEN-1 protein 0.0224 0.4288 0.4288
Giardia lamblia Epsilon tubulin 0.0053 0.0887 0.0684
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0266 0.0294
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0266 0.0294
Onchocerca volvulus 0.0021 0.0266 0.0248
Brugia malayi hypothetical protein 0.0016 0.0159 0.0159
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.103 0.1141
Trypanosoma cruzi zeta tubulin, putative 0.0053 0.0887 0.2024
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.1049 0.1027
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0218 0.0241
Trypanosoma cruzi beta tubulin, putative 0.0224 0.4288 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0511 1 1
Schistosoma mansoni tubulin subunit beta 0.0224 0.4288 0.4749
Loa Loa (eye worm) hypothetical protein 0.002 0.0247 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0754 0.0621
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0304 0.0281
Echinococcus multilocularis transient receptor potential ion channel A 0.0092 0.1673 0.1853
Echinococcus multilocularis transient receptor potential gamma protein 0.0095 0.1736 0.1923
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.1049 0.1162
Trypanosoma brucei epsilon tubulin 0.0121 0.225 0.5204
Trypanosoma brucei alpha tubulin 0.0169 0.3204 0.745
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0462 0.9028 1
Leishmania major epsilon tubulin, putative 0.0121 0.225 0.5204
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0814 0.0814
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0266 0.0532
Echinococcus granulosus death domain containing protein 0.0086 0.1552 0.1719
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0051 0.0847 0.0939
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0218 0.0455
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0218 0.0455
Loa Loa (eye worm) hypothetical protein 0.0009 0.0024 0.0024
Loa Loa (eye worm) tubulin beta-2A chain 0.0224 0.4288 0.4288
Loa Loa (eye worm) hypothetical protein 0.0095 0.1736 0.1736
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0462 0.9028 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0493 0.0493
Echinococcus multilocularis protoporphyrinogen oxidase 0.0021 0.0251 0.0278
Schistosoma mansoni dep domain containing protein 0.0009 0.0018 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0101 0.0145
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1685 0.3896
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0333 0.0444
Trichomonas vaginalis tubulin epsilon chain, putative 0.0169 0.3204 0.3107
Echinococcus granulosus dnaJ subfamily B 0.0402 0.7826 0.8668
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1105 0.1224
Trypanosoma cruzi ABC transporter, putative 0.0061 0.1049 0.2403
Trichomonas vaginalis tubulin alpha chain, putative 0.0069 0.1204 0.1078
Loa Loa (eye worm) hypothetical protein 0.0086 0.1552 0.1552
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0251 0.0544
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0062 0.0069
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Schistosoma mansoni alpha tubulin 0.0169 0.3204 0.3549
Giardia lamblia Alpha-tubulin 0.0169 0.3204 0.3053
Loa Loa (eye worm) tubulin alpha chain 0.0169 0.3204 0.3204
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0251 0.0227
Trypanosoma brucei alpha tubulin 0.0169 0.3204 0.745
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Loa Loa (eye worm) tubulin alpha 2 0.0117 0.2158 0.2158
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0061 0.1049 0.2376
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0478 0.1032
Echinococcus multilocularis Polycystic kidney disease protein 0.0077 0.1377 0.1525
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Toxoplasma gondii beta-1 tubulin, putative 0.0224 0.4288 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0018 0.0018
Loa Loa (eye worm) tubulin alpha-3 chain 0.0101 0.1841 0.1841
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0018 0.002
Leishmania major gamma-tubulin 0.0121 0.225 0.5204
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.015 0.0166
Leishmania major beta tubulin 0.0224 0.4288 1
Echinococcus granulosus beta tubulin 0.0224 0.4288 0.4749
Echinococcus granulosus Tubulin beta 2C chain 0.0224 0.4288 0.4749
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0266 0.0242
Loa Loa (eye worm) alpha-tubulin 0.0169 0.3204 0.3204
Schistosoma mansoni rotamase 0.0033 0.0493 0.0546
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Plasmodium falciparum tubulin beta chain 0.0224 0.4288 1
Schistosoma mansoni hypothetical protein 0.0402 0.7826 0.8668
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0511 1 1
Echinococcus granulosus tubulin beta 4A class IVa 0.0224 0.4288 0.4749
Brugia malayi alpha-tubulin 0.0169 0.3204 0.3204
Leishmania major beta tubulin 0.0224 0.4288 1
Echinococcus granulosus tubulin alpha chain 0.0169 0.3204 0.3549
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0903 0.2073
Echinococcus granulosus tar DNA binding protein 0.0064 0.1105 0.1224
Toxoplasma gondii alpha tubulin TUBA1 0.0169 0.3204 0.7462
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0021 0.0251 0.0278
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.015 0.015
Leishmania major beta tubulin 0.0224 0.4288 1
Brugia malayi Protein kinase domain containing protein 0.0086 0.1558 0.1558
Plasmodium vivax tubulin gamma chain, putative 0.0121 0.225 0.5076
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0121 0.225 0.5228
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Schistosoma mansoni netrin receptor unc5 0.0086 0.1552 0.1719
Onchocerca volvulus 0.0023 0.0304 0.0286
Loa Loa (eye worm) tubulin beta-4 chain 0.0224 0.4288 0.4288
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.1049 0.1162
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0021 0.0251 0.0244
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0266 0.0126
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0018 0.002
Mycobacterium ulcerans cell division protein FtsZ 0.0053 0.0887 0.0865
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0266 0.0294
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0511 1 1
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0018 0.002
Schistosoma mansoni tubulin subunit beta 0.0224 0.4288 0.4749
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0333 0.0737
Schistosoma mansoni hypothetical protein 0.0167 0.3149 0.3488
Loa Loa (eye worm) ABC transporter 0.0052 0.0866 0.0866
Loa Loa (eye worm) hypothetical protein 0.0019 0.0218 0.0218
Trypanosoma cruzi zeta tubulin, putative 0.0053 0.0887 0.2024
Entamoeba histolytica tubulin alpha-1 chain 0.0169 0.3204 0.3188
Mycobacterium leprae cell division protein FtsZ 0.0053 0.0887 1
Trypanosoma brucei ABC transporter, putative 0.001 0.0043 0.0007
Brugia malayi Tubulin gamma chain 0.0121 0.225 0.225
Plasmodium vivax multidomain scavenger receptor, putative 0.0077 0.1377 0.2966
Trichomonas vaginalis tubulin beta chain, putative 0.0169 0.3204 0.3107
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0086 0.1552 0.1719
Schistosoma mansoni transient receptor potential channel 4 0.0095 0.1736 0.1923
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0266 0.0242
Mycobacterium ulcerans hypothetical protein 0.0023 0.0304 0.0281
Leishmania major beta tubulin 0.0224 0.4288 1
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1685 0.1566
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.001 0.0043 0.0043
Giardia lamblia Gamma tubulin 0.0121 0.225 0.2078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0304 0.0281
Schistosoma mansoni apoptosis regulator bax 0.0164 0.3097 0.343
Loa Loa (eye worm) hypothetical protein 0.0033 0.0506 0.0506
Plasmodium vivax tubulin alpha chain, putative 0.0169 0.3204 0.7382
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.015 0.0166
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0266 0.0126
Trypanosoma brucei beta tubulin 0.0121 0.225 0.5204
Toxoplasma gondii beta-tubulin, putative 0.0224 0.4288 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0218 0.042
Echinococcus multilocularis dna polymerase eta 0.0019 0.0218 0.0241
Onchocerca volvulus 0.0077 0.1377 0.1361
Loa Loa (eye worm) hypothetical protein 0.0021 0.0251 0.0251
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0511 1 1
Trypanosoma brucei tubulin gamma chain 0.0121 0.225 0.5204
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0018 0.002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.1685 0.1665
Trypanosoma brucei unspecified product 0.0013 0.0101 0.0145
Loa Loa (eye worm) hypothetical protein 0.0021 0.0251 0.0251
Brugia malayi CXXC zinc finger family protein 0.0028 0.0402 0.0402
Plasmodium falciparum protoporphyrinogen oxidase 0.0021 0.0251 0.0244
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0168 0.0144
Echinococcus granulosus Tubulin beta 2C chain 0.0224 0.4288 0.4749
Schistosoma mansoni hypothetical protein 0.0035 0.0544 0.0602
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0511 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1685 0.1566
Giardia lamblia ABC transporter 0.006 0.103 0.083
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0021 0.0251 0.0244
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0035 0.0546 0.0605
Trypanosoma cruzi epsilon tubulin, putative 0.0121 0.225 0.5221
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0218 0.0455
Trypanosoma cruzi ABC transporter, putative 0.001 0.0043 0.0043
Mycobacterium tuberculosis Cell division protein FtsZ 0.0053 0.0887 0.0865
Echinococcus granulosus tubulin alpha 1C chain 0.0169 0.3204 0.3549
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0511 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0304 0.0281
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0266 0.0294
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0039 0.0036
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.015 0.0259
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0018 0.002
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0266 0.028
Toxoplasma gondii beta tubulin 0.0224 0.4288 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0169 0.3204 0.3107
Leishmania major beta tubulin 0.0224 0.4288 1
Trichomonas vaginalis rotamase, putative 0.0033 0.0493 0.0357
Loa Loa (eye worm) hypothetical protein 0.0021 0.0266 0.0266
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0266 0.0126
Leishmania major p-glycoprotein 0.0021 0.0266 0.0532
Loa Loa (eye worm) hypothetical protein 0.0021 0.0266 0.0266
Trichomonas vaginalis tubulin epsilon chain, putative 0.0053 0.0887 0.0756
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.1049 0.1027
Trypanosoma brucei zeta tubulin 0.0053 0.0887 0.1995
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0187 0.009
Brugia malayi hypothetical protein 0.0077 0.1377 0.1377
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0266 0.0266
Echinococcus multilocularis tubulin alpha chain 0.0169 0.3204 0.3549
Schistosoma mansoni tubulin subunit beta 0.0224 0.4288 0.4749
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0272 0.5245 0.5234
Echinococcus granulosus Tubulin beta 2C chain 0.0224 0.4288 0.4749
Plasmodium falciparum LCCL domain-containing protein 0.0077 0.1377 0.2966
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0061 0.1049 0.1027
Echinococcus multilocularis Tubulin beta 2C chain 0.0224 0.4288 0.4749
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0018 0.0018
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0511 1 1
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.1105 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1685 0.1566
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0187 0.0163
Trypanosoma brucei beta tubulin 0.0224 0.4288 1
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Entamoeba histolytica hypothetical protein 0.0035 0.0544 0.0521
Echinococcus multilocularis tubulin subunit TubB 0.0169 0.3204 0.3549
Brugia malayi Tubulin alpha chain 0.0169 0.3204 0.3204
Schistosoma mansoni transient receptor potential channel 0.0095 0.1736 0.1923
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0018 0.002
Echinococcus granulosus Polycystic kidney disease protein 0.0077 0.1377 0.1525
Trichomonas vaginalis tubulin beta chain, putative 0.0169 0.3204 0.3107
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.1049 0.1162
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0164 0.3097 0.343
Trichomonas vaginalis tubulin alpha chain, putative 0.0069 0.1204 0.1078
Toxoplasma gondii ATP-binding cassette G family transporter ABCG96 0.001 0.0043 0.0057
Leishmania major beta tubulin 0.0224 0.4288 1
Schistosoma mansoni tubulin subunit beta 0.0224 0.4288 0.4749
Toxoplasma gondii ATP-binding cassette G family transporter ABCG89 0.001 0.0043 0.0057
Trypanosoma brucei epsilon tubulin 0.0121 0.225 0.5204
Plasmodium falciparum tubulin epsilon chain, putative 0.0121 0.225 0.5076
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0218 0.042
Toxoplasma gondii ATP-binding cassette G family transporter ABCG87 0.001 0.0043 0.0057
Loa Loa (eye worm) hypothetical protein 0.0169 0.3204 0.3204
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0266 0.0126
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Echinococcus granulosus lipoxygenase domain containing protein 0.0077 0.1377 0.1525
Echinococcus multilocularis Tubulin alpha 1 chain 0.0169 0.3204 0.3549
Echinococcus granulosus alpha tubulin 0.0169 0.3204 0.3549
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0266 0.028
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Trypanosoma brucei polo-like protein kinase 0.0093 0.1685 0.3874
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0018 0.0018
Echinococcus multilocularis Tubulin alpha 1 chain 0.0169 0.3204 0.3549
Echinococcus granulosus tubulin beta 1 chain 0.0224 0.4288 0.4749
Trypanosoma brucei unspecified product 0.0013 0.0101 0.0145
Echinococcus granulosus lipoxygenase domain containing protein 0.0077 0.1377 0.1525
Echinococcus granulosus tubulin alpha chain 0.0169 0.3204 0.3549
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.015 0.0294
Echinococcus granulosus peroxisome assembly protein 26 0.0169 0.3204 0.3549
Echinococcus multilocularis RUN 0.0077 0.1377 0.1525
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0218 0.0194
Echinococcus multilocularis GPCR, family 2 0.0015 0.0149 0.0165
Schistosoma mansoni dishevelled 0.0009 0.0018 0.002
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0251 0.0531
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0018
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0304 0.0281
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0266 0.0294
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0131 0.2452 0.2716
Loa Loa (eye worm) hypothetical protein 0.0021 0.0251 0.0251
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.015 0.0166
Schistosoma mansoni lipoxygenase 0.0462 0.9028 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0218 0.0077
Schistosoma mansoni hypothetical protein 0.0011 0.0062 0.0069
Echinococcus multilocularis hypothetical protein 0.0169 0.3204 0.3549
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0218 0.0194
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0266 0.0126
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0266 0.0294
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0304 0.0281
Schistosoma mansoni tubulin subunit beta 0.0053 0.0887 0.0983
Schistosoma mansoni tubulin subunit beta 0.0224 0.4288 0.4749
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0149 0.0165
Leishmania major beta tubulin 0.0224 0.4288 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0086 0.1552 0.1719
Loa Loa (eye worm) hypothetical protein 0.0086 0.1552 0.1552
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0218 0.0241
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0018 0.0018
Brugia malayi isocitrate dehydrogenase 0.0016 0.015 0.015
Onchocerca volvulus 0.0028 0.0402 0.0384
Trichomonas vaginalis abcb9, putative 0.0021 0.0266 0.0126
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0544 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1685 0.1566
Leishmania major beta tubulin 0.0224 0.4288 1
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0266 0.0242
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0018 0.002
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0018 0.002
Brugia malayi Tubulin beta-1 chain 0.0224 0.4288 0.4288
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0018 0.002
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0061 0.1049 0.2403
Loa Loa (eye worm) hypothetical protein 0.0049 0.0814 0.0814
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0478 0.1076
Echinococcus granulosus Tubulin beta 2C chain 0.0224 0.4288 0.4749
Echinococcus multilocularis tubulin alpha 0.0121 0.225 0.2492
Echinococcus multilocularis tubulin delta chain 0.0053 0.0887 0.0983
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0164 0.3097 0.343
Loa Loa (eye worm) hypothetical protein 0.0023 0.0304 0.0304
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.1105 0.1105
Trypanosoma brucei epsilon tubulin 0.0121 0.225 0.5204
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0021 0.0251 0.0278
Trichomonas vaginalis tubulin beta chain, putative 0.0169 0.3204 0.3107
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0149 0.0165
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0266 0.0242
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0511 1 1
Schistosoma mansoni tubulin subunit epsilon 0.0121 0.225 0.2492
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0511 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0506 0.0506
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0333 0.0692
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0149 0.0149
Schistosoma mansoni tubulin subunit alpha 0.0169 0.3204 0.3549
Echinococcus multilocularis beta tubulin 0.0224 0.4288 0.4749
Brugia malayi tubulin alpha-2 chain 0.0169 0.3204 0.3204
Trichomonas vaginalis tubulin, putative 0.0069 0.1204 0.1078
Plasmodium vivax ABC transporter G family member 2, putative 0.0061 0.1049 0.2173
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0015 0.0016
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0734 0.0734
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0251 0.0278
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0218 0.0218
Entamoeba histolytica hypothetical protein 0.0035 0.0544 0.0521
Leishmania major beta tubulin 0.0224 0.4288 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0062 0.0069
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0187
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0814 0.0814
Schistosoma mansoni hypothetical protein 0.0033 0.0506 0.0561
Echinococcus multilocularis Tubulin beta 2C chain 0.0224 0.4288 0.4749
Brugia malayi tubulin alpha chain - mouse 0.0169 0.3204 0.3204
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0293 0.5655 0.5644
Echinococcus multilocularis netrin receptor unc 5 0.0086 0.1552 0.1719
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0187 0.009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0266 0.0126
Trypanosoma brucei alpha tubulin 0.0169 0.3204 0.745
Giardia lamblia Beta tubulin 0.0224 0.4288 0.416
Echinococcus granulosus tubulin delta chain 0.0053 0.0887 0.0983
Echinococcus multilocularis tubulin subunit beta 0.0224 0.4288 0.4749
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0304 0.0281
Trypanosoma brucei ABC transporter, putative 0.0061 0.1049 0.2376
Loa Loa (eye worm) hypothetical protein 0.0181 0.3442 0.3442
Echinococcus granulosus Ankyrin 0.0086 0.1552 0.1719
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0251 0.0244
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0544 0.0602
Echinococcus multilocularis lipoxygenase domain containing protein 0.0077 0.1377 0.1525
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0266 0.0126
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0018 0.0018
Echinococcus multilocularis ATP binding cassette sub family G 0.0061 0.1049 0.1162
Schistosoma mansoni multidrug resistance protein 0.0021 0.0266 0.0294
Schistosoma mansoni transient receptor potential channel 0.0063 0.1094 0.1212
Brugia malayi Tubulin beta chain 0.0053 0.0887 0.0887
Trichomonas vaginalis abcb9, putative 0.0021 0.0266 0.0126
Echinococcus multilocularis Tubulin beta 2C chain 0.0224 0.4288 0.4749
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.1049 0.1162
Trypanosoma cruzi tubulin gamma chain 0.0121 0.225 0.5221
Echinococcus multilocularis lipoxygenase domain containing protein 0.0077 0.1377 0.1525
Schistosoma mansoni ABC transporter 0.0009 0.0024 0.0027
Schistosoma mansoni cpg binding protein 0.003 0.0434 0.0481
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0304 0.3244
Leishmania major hypothetical protein, conserved 0.0025 0.0333 0.0692
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0266 0.0126
Leishmania major beta tubulin 0.0224 0.4288 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0734 0.0813
Mycobacterium ulcerans monoamine oxidase 0.0021 0.0251 0.0227
Trichomonas vaginalis tubulin alpha chain, putative 0.0224 0.4288 0.4206
Brugia malayi DIX domain containing protein 0.0009 0.0018 0.0018
Echinococcus granulosus transient receptor potential ion channel A 0.0092 0.1673 0.1853
Echinococcus multilocularis ATP binding cassette sub family B 0.002 0.0247 0.0274
Leishmania major beta tubulin 0.0224 0.4288 1
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0511 1 1
Schistosoma mansoni tumor necrosis factor receptor related 0.0131 0.2452 0.2716
Schistosoma mansoni tubulin subunit gamma 0.0121 0.225 0.2492
Loa Loa (eye worm) doublecortin family protein 0.0077 0.1377 0.1377
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.1685 0.1867
Trichomonas vaginalis tubulin gamma chain, putative 0.0224 0.4288 0.4206
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0086 0.1552 0.1552
Trichomonas vaginalis tubulin epsilon chain, putative 0.0224 0.4288 0.4206
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0511 1 1
Brugia malayi Tubulin beta chain 0.0069 0.1204 0.1204
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0734 0.0734
Loa Loa (eye worm) tubulin beta chain 0.0224 0.4288 0.4288
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0022 0.0285 0.0624
Schistosoma mansoni amine oxidase 0.0021 0.0251 0.0278
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0018 0.002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0304 0.0281
Echinococcus multilocularis tubulin alpha 3 chain 0.0169 0.3204 0.3549
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0043 0.0043
Schistosoma mansoni cpg binding protein 0.003 0.0434 0.0481
Echinococcus multilocularis tar DNA binding protein 0.0064 0.1105 0.1224
Echinococcus multilocularis cpg binding protein 0.003 0.0434 0.0481
Trypanosoma brucei tubulin delta chain 0.0053 0.0887 0.1995
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0478 0.1064
Brugia malayi hypothetical protein 0.0148 0.2791 0.2791
Trypanosoma brucei beta tubulin 0.0224 0.4288 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.015 0.0166
Echinococcus granulosus cpg binding protein 0.003 0.0434 0.0481
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0053 0.0887 0.2035
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0266 0.0126
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.015 0.0126
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.015 0.0166
Loa Loa (eye worm) apoptosis regulator protein 0.0164 0.3097 0.3097
Schistosoma mansoni hypothetical protein 0.0164 0.3097 0.343
Trypanosoma brucei beta tubulin 0.0224 0.4288 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0304 0.0304
Brugia malayi Immunoglobulin I-set domain containing protein 0.0086 0.1552 0.1552
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0086 0.1552 0.1719
Plasmodium falciparum alpha tubulin 1 0.0169 0.3204 0.7382
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.0142 0.0157
Loa Loa (eye worm) hypothetical protein 0.0021 0.0251 0.0251
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Mycobacterium ulcerans dehydrogenase 0.0021 0.0251 0.0227
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0266 0.0294
Echinococcus multilocularis beta tubulin 0.0224 0.4288 0.4749
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0266 0.0294
Trichomonas vaginalis tubulin gamma chain, putative 0.0121 0.225 0.2139
Brugia malayi hypothetical protein 0.0009 0.0018 0.0018
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0051 0.0847 0.0825
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0511 1 1
Schistosoma mansoni transient receptor potential channel 0.0063 0.1094 0.1212
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0187
Trypanosoma brucei alpha tubulin, putative 0.0069 0.1204 0.2742
Brugia malayi SWIRM domain containing protein 0.0021 0.0251 0.0251
Trichomonas vaginalis tubulin beta chain, putative 0.0169 0.3204 0.3107
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0101 0.0145
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0304 0.0623
Loa Loa (eye worm) hypothetical protein 0.0077 0.1377 0.1377
Echinococcus granulosus Tubulin alpha 1 chain 0.0169 0.3204 0.3549
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.002 0.0247 0.0274
Plasmodium falciparum ABC transporter G family member 2 0.0061 0.1049 0.2173
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0015 0.0016
Schistosoma mansoni hypothetical protein 0.0164 0.3097 0.343
Giardia lamblia Beta tubulin 0.0224 0.4288 0.416
Loa Loa (eye worm) beta-tubulin 0.0224 0.4288 0.4288
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.015 0.0259
Trichomonas vaginalis tubulin epsilon chain, putative 0.0169 0.3204 0.3107
Schistosoma mansoni hypothetical protein 0.0015 0.0149 0.0165
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0266 0.0294
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.015 0.0307
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0304 0.0304
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0168 0.0144
Trichomonas vaginalis abcb9, putative 0.0021 0.0266 0.0126
Echinococcus multilocularis tubulin alpha 1C chain 0.0169 0.3204 0.3549
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0149 0.0165
Leishmania major beta tubulin 0.0224 0.4288 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0734 0.0813
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0266 0.0266
Schistosoma mansoni alpha tubulin 0.0169 0.3204 0.3549
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.015 0.0166
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0039 0.0049
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0018
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0018 0.002
Brugia malayi Tubulin alpha chain 0.0053 0.0887 0.0887
Brugia malayi multidrug resistance protein 3 0.0021 0.0266 0.0266
Loa Loa (eye worm) tubulin gamma chain 0.0121 0.225 0.225
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0333 0.0444
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0304 0.0281
Schistosoma mansoni cpg binding protein 0.0028 0.0402 0.0445
Chlamydia trachomatis protoporphyrinogen oxidase 0.0021 0.0251 0.8088
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0266 0.0294
Plasmodium falciparum alpha tubulin 2 0.0169 0.3204 0.7382
Schistosoma mansoni multidrug resistance protein 0.0021 0.0266 0.0294
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.015 0.0166
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0117 0.2158 0.2158
Trichomonas vaginalis tubulin gamma chain, putative 0.0121 0.225 0.2139
Echinococcus multilocularis tubulin epsilon chain 0.0121 0.225 0.2492
Loa Loa (eye worm) TAR-binding protein 0.0064 0.1105 0.1105
Schistosoma mansoni tubulin subunit beta 0.0224 0.4288 0.4749
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.001 0.0043 0.0043
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0293 0.5655 0.5644
Echinococcus granulosus ATP binding cassette sub family G 0.0061 0.1049 0.1162
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0333 0.0725
Trypanosoma brucei alpha tubulin 0.0169 0.3204 0.745
Echinococcus granulosus geminin 0.0167 0.3149 0.3488
Brugia malayi hypothetical protein 0.0035 0.0544 0.0544
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0402 0.0402
Trypanosoma brucei beta tubulin 0.0224 0.4288 1
Toxoplasma gondii alpha-tubulin I, putative 0.0169 0.3204 0.7462
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.2172 0.2172
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.015 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0887 0.0756
Trichomonas vaginalis tubulin, putative 0.0053 0.0887 0.0756
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0218 0.042
Loa Loa (eye worm) hypothetical protein 0.0023 0.0304 0.0304
Brugia malayi Transient-receptor-potential like protein 0.0035 0.0546 0.0546
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0164 0.3097 0.3097
Trypanosoma cruzi alpha tubulin, putative 0.0169 0.3204 0.7459
Brugia malayi N-terminal motif family protein 0.0181 0.3442 0.3442
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0266 0.0294
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0218 0.0218
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0012 0.0012
Schistosoma mansoni lipoxygenase 0.0323 0.6264 0.6938
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0304 0.0281
Loa Loa (eye worm) hypothetical protein 0.0032 0.0483 0.0483
Trypanosoma cruzi tubulin delta chain 0.0053 0.0887 0.2024
Loa Loa (eye worm) hypothetical protein 0.006 0.1031 0.1031
Brugia malayi ABC transporter family protein 0.0052 0.0866 0.0866
Echinococcus multilocularis tubulin alpha chain 0.0169 0.3204 0.3549
Schistosoma mansoni hypothetical protein 0.0167 0.3149 0.3488
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0266 0.0579
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0218 0.0455
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0069 0.1204 0.1078
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0039 0.0036
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0218 0.0194
Trypanosoma brucei zeta tubulin, putative 0.0053 0.0887 0.1995
Entamoeba histolytica tubulin gamma chain 0.0121 0.225 0.2232
Brugia malayi amine oxidase, flavin-containing family protein 0.0021 0.0251 0.0251
Schistosoma mansoni smdr2 0.0021 0.0266 0.0294
Brugia malayi beta-tubulin, identical 0.0224 0.4288 0.4288
Echinococcus granulosus tubulin epsilon chain 0.0121 0.225 0.2492
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Echinococcus granulosus Tubulin alpha 1 chain 0.0169 0.3204 0.3549
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0164 0.3097 0.343
Brugia malayi Cell division protein ftsZ 0.0053 0.0887 0.0887
Echinococcus granulosus tubulin alpha chain 0.0169 0.3204 0.3549
Echinococcus multilocularis 0.0021 0.0251 0.0278
Trichomonas vaginalis tubulin alpha chain, putative 0.0121 0.225 0.2139
Echinococcus granulosus GPCR family 2 0.0015 0.0149 0.0165
Trichomonas vaginalis tubulin beta chain, putative 0.0169 0.3204 0.3107
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0304 0.0623
Echinococcus granulosus transient receptor potential gamma protein 0.0095 0.1736 0.1923
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0266 0.0126
Loa Loa (eye worm) hypothetical protein 0.0148 0.2791 0.2791
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0018 0.002
Loa Loa (eye worm) alpha-tubulin 0.0169 0.3204 0.3204
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0251 0.0227
Echinococcus granulosus tubulin alpha 1C chain 0.0169 0.3204 0.3549
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1685 0.1566
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0218 0.0241
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0164 0.3097 0.343
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Brugia malayi hypothetical protein 0.0077 0.1377 0.1377
Brugia malayi Tubulin alpha-2 chain 0.0169 0.3204 0.3204
Brugia malayi Uncoordinated protein 44 0.0086 0.1552 0.1552
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0266 0.0126
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0021 0.0251 0.0278
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.1094 0.1212
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0304 0.0281
Echinococcus granulosus RUN 0.0077 0.1377 0.1525
Schistosoma mansoni tubulin subunit alpha 0.0169 0.3204 0.3549
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0304 0.0281
Leishmania major beta tubulin 0.0224 0.4288 1
Leishmania major ATP-binding cassette protein subfamily G, member 5, putative 0.001 0.0043 0.0007
Loa Loa (eye worm) RNA binding protein 0.0064 0.1105 0.1105
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Leishmania major beta tubulin 0.0224 0.4288 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0251 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0493 0.0357
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0218 0.042
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.1685 0.3874
Schistosoma mansoni hypothetical protein 0.0164 0.3097 0.343
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1105 0.1224
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0266 0.0126
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0266 0.0579
Echinococcus granulosus tubulin alpha chain 0.0169 0.3204 0.3549
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.1685 0.167
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0053 0.0887 0.0756
Loa Loa (eye worm) tubulin alpha-2 chain 0.0169 0.3204 0.3204
Brugia malayi ABC transporter family protein 0.0021 0.0266 0.0266
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1105 0.1224
Leishmania major beta tubulin 0.0224 0.4288 1
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0754 0.0621
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0333 0.0725
Schistosoma mansoni hypothetical protein 0.0015 0.0149 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0101 0.0145
Echinococcus multilocularis tubulin alpha chain 0.0169 0.3204 0.3549
Loa Loa (eye worm) tubulin alpha chain 0.0169 0.3204 0.3204
Brugia malayi hypothetical protein 0.0009 0.0018 0.0018
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0266 0.0126
Onchocerca volvulus 0.0077 0.1377 0.1361
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0218 0.0241
Trichomonas vaginalis tubulin beta chain, putative 0.0069 0.1204 0.1078
Schistosoma mansoni kinase 0.0047 0.0778 0.0862
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0131 0.2452 0.2716
Loa Loa (eye worm) hypothetical protein 0.0117 0.2158 0.2158
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0149 0.0165
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0734 0.0813
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0218 0.0194
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.3442 0.343
Giardia lamblia Delta tubulin 0.0053 0.0887 0.0684
Schistosoma mansoni DNA polymerase eta 0.0019 0.0218 0.0241
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0043 0.0043
Schistosoma mansoni polycystin 1-related 0.0077 0.1377 0.1525
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0053 0.0887 0.2035
Treponema pallidum cell division protein FtsZ 0.0053 0.0887 0.5
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0061 0.1049 0.2376
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0187
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0218 0.042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0266 0.0126
Entamoeba histolytica hypothetical protein 0.0035 0.0544 0.0521
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0251 0.0244
Echinococcus multilocularis tubulin alpha chain 0.0169 0.3204 0.3549
Schistosoma mansoni hypothetical protein 0.0086 0.1552 0.1719
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0251 0.0244
Echinococcus multilocularis Tubulin alpha 1 chain 0.0169 0.3204 0.3549
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.015 0.0294
Entamoeba histolytica tubulin family protein 0.0224 0.4288 0.4274
Plasmodium vivax tubulin beta chain, putative 0.0224 0.4288 1
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0164 0.3097 0.343
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0168 0.0144
Plasmodium vivax tubulin alpha chain, putative 0.0169 0.3204 0.7382
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0218 0.0077
Schistosoma mansoni ABC transporter 0.0052 0.0866 0.0959
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1105 0.1224
Toxoplasma gondii ATP-binding cassette G family transporter ABCG107 0.001 0.0043 0.0057
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0734 0.0813
Echinococcus granulosus tubulin alpha chain 0.0169 0.3204 0.3549
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0266 0.0242
Leishmania major beta tubulin 0.0224 0.4288 1
Brugia malayi Tubulin alpha-2 chain 0.0169 0.3204 0.3204
Schistosoma mansoni alpha tubulin 0.0169 0.3204 0.3549
Echinococcus granulosus tubulin gamma 1 chain 0.0121 0.225 0.2492
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0187
Echinococcus granulosus Tubulin beta 2C chain 0.0224 0.4288 0.4749
Brugia malayi Isocitrate dehydrogenase 0.0016 0.015 0.015
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0218 0.042
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0025 0.0333 0.0333
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1685 0.3896
Leishmania major beta tubulin 0.0224 0.4288 1
Loa Loa (eye worm) tubulin beta-1 chain 0.0224 0.4288 0.4288
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0887 0.0756
Entamoeba histolytica tubulin alpha chain, putative 0.0169 0.3204 0.3188
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.2172 0.2172
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0266 0.0126
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0478 0.1064
Trichomonas vaginalis tubulin, putative 0.0069 0.1204 0.1078
Loa Loa (eye worm) BEN-1 protein 0.0224 0.4288 0.4288
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0149 0.0149
Leishmania major zeta tubulin, putative 0.0053 0.0887 0.1995
Loa Loa (eye worm) tubulin beta chain 0.0053 0.0887 0.0887
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0333 0.0444
Echinococcus granulosus tubulin subunit beta 0.0224 0.4288 0.4749
Schistosoma mansoni rab6-interacting 0.0077 0.1377 0.1525
Echinococcus multilocularis Ankyrin 0.0086 0.1552 0.1719
Schistosoma mansoni ankyrin 23/unc44 0.0086 0.1552 0.1719
Plasmodium falciparum tubulin gamma chain 0.0121 0.225 0.5076
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0061 0.1049 0.2413
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0266 0.0242
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.015 0.0259
Schistosoma mansoni loxhd1 0.0077 0.1377 0.1525
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0009 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0164 0.3097 0.3097
Trichomonas vaginalis tubulin alpha chain, putative 0.0069 0.1204 0.1078
Brugia malayi RE11181p 0.0009 0.0024 0.0024
Brugia malayi MH2 domain containing protein 0.0117 0.2172 0.2172
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0734 0.0813
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Echinococcus multilocularis geminin 0.0167 0.3149 0.3488
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0478 0.0455
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.1094 0.1212
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0117 0.2158 0.2046
Echinococcus granulosus TRP transient receptor potential channel 0.0035 0.0546 0.0605
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0734 0.0813
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Schistosoma mansoni tubulin subunit alpha 0.0053 0.0887 0.0983
Brugia malayi hypothetical protein 0.0025 0.0333 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.1685 0.1867
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0814 0.0814
Loa Loa (eye worm) hypothetical protein 0.0101 0.1841 0.1841
Brugia malayi hypothetical protein 0.0009 0.0024 0.0024
Echinococcus multilocularis tubulin alpha chain 0.0169 0.3204 0.3549
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0304 0.3244
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0218 0.0241
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.0142 0.0157
Echinococcus multilocularis tubulin beta 1 chain 0.0224 0.4288 0.4749
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0493 0.0493
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0224 0.4288 0.4749
Echinococcus granulosus tubulin alpha 3 chain 0.0169 0.3204 0.3549
Entamoeba histolytica hypothetical protein 0.0035 0.0544 0.0521
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0266 0.0126
Echinococcus multilocularis multidrug resistance protein 1 0.0015 0.0142 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1685 0.1566
Loa Loa (eye worm) tubulin alpha 2 0.0117 0.2158 0.2158
Giardia lamblia Beta tubulin 0.0224 0.4288 0.416
Schistosoma mansoni dishevelled 0.0009 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.0018
Trichomonas vaginalis rotamase, putative 0.0032 0.0478 0.0341
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0218 0.0218
Schistosoma mansoni tubulin subunit delta 0.0053 0.0887 0.0983
Echinococcus multilocularis expressed protein 0.0033 0.0493 0.0546
Trichomonas vaginalis tubulin beta chain, putative 0.0224 0.4288 0.4206
Brugia malayi Doublecortin family protein 0.0077 0.1377 0.1377
Mycobacterium ulcerans oxidoreductase 0.0021 0.0251 0.0227
Echinococcus granulosus Tubulin alpha 1 chain 0.0169 0.3204 0.3549
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.1685 0.1867
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Trichomonas vaginalis tubulin, putative 0.0224 0.4288 0.4206
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0266 0.0294
Leishmania major alpha tubulin 0.0169 0.3204 0.745
Loa Loa (eye worm) hypothetical protein 0.0035 0.0546 0.0546
Plasmodium vivax tubulin epsilon chain, putative 0.0121 0.225 0.5076
Entamoeba histolytica ABC transporter, putative 0.0061 0.1049 0.1027
Leishmania major DNA polymerase kappa, putative 0.0019 0.0218 0.042
Echinococcus granulosus beta tubulin 0.0224 0.4288 0.4749
Echinococcus granulosus dna polymerase eta 0.0019 0.0218 0.0241
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1685 0.1566
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.1685 0.1685
Schistosoma mansoni hypothetical protein 0.0015 0.0149 0.0165
Trichomonas vaginalis taga, putative 0.0021 0.0266 0.0126
Trypanosoma cruzi tubulin delta chain 0.0053 0.0887 0.2024
Schistosoma mansoni hypothetical protein 0.0077 0.1377 0.1525
Echinococcus granulosus tubulin alpha 0.0121 0.225 0.2492
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0168 0.0144
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0061 0.1049 0.1162
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0266 0.0242
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0734 0.0813
Plasmodium falciparum tubulin delta chain, putative 0.0053 0.0887 0.1782
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0266 0.0294
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0544 0.0602
Onchocerca volvulus 0.0511 1 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0149 0.0149
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.1094 0.1212
Giardia lamblia Alpha-tubulin 0.0169 0.3204 0.3053
Brugia malayi TAR-binding protein 0.0064 0.1105 0.1105
Echinococcus granulosus expressed protein 0.0033 0.0493 0.0546
Echinococcus multilocularis tubulin alpha 3 chain 0.0169 0.3204 0.3549
Leishmania major DNA polymerase eta, putative 0.0019 0.0218 0.042
Onchocerca volvulus Netrin receptor homolog 0.0086 0.1552 0.1536
Leishmania major ATP-binding cassette protein subfamily G, member 2, putative 0.001 0.0043 0.0007
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0266 0.0126
Onchocerca volvulus 0.0021 0.0251 0.0233
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Echinococcus granulosus tubulin subunit TubB 0.0169 0.3204 0.3549
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0131 0.2452 0.2716
Schistosoma mansoni multidrug resistance protein 0.0021 0.0266 0.0294
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0478 0.1032
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0131 0.2452 0.2716
Echinococcus granulosus tubulin alpha 3 chain 0.0169 0.3204 0.3549
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0266 0.0126
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0101 0.1841 0.1724
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0187 0.0163
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.7826 0.8668
Schistosoma mansoni amine oxidase 0.0021 0.0251 0.0278
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.1094 0.1212
Echinococcus multilocularis Tubulin beta 2C chain 0.0224 0.4288 0.4749
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0266 0.0126
Schistosoma mansoni hypothetical protein 0.0015 0.0149 0.0165
Schistosoma mansoni rab6-interacting 0.0077 0.1377 0.1525
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0251 0.0278
Loa Loa (eye worm) hypothetical protein 0.0009 0.0024 0.0024
Echinococcus multilocularis peroxisome assembly protein 26 0.0169 0.3204 0.3549
Echinococcus multilocularis tubulin alpha 1C chain 0.0169 0.3204 0.3549
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.1685 0.1685
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1105 0.1224
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0218 0.0194
Plasmodium vivax delta tubulin, putative 0.0053 0.0887 0.1782
Loa Loa (eye worm) hypothetical protein 0.0077 0.1377 0.1377

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0033 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 2.0588 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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