TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 416.4 | Formula: C20H19F3N6O
H donors: 1 H acceptors: 4 LogP: 0.64 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: N[C@H](Cc1cc(F)c(cc1F)F)CC(=O)N1CCn2c(C1)c(nn2)c1ccncc1
InChi: 1S/C20H19F3N6O/c21-15-10-17(23)16(22)8-13(15)7-14(24)9-19(30)28-5-6-29-18(11-28)20(26-27-29)12-1-3-25-4-2-12/h1-4,8,10,14H,5-7,9,11,24H2/t14-/m1/s1
InChiKey: QCIARNRITBGBSW-CQSZACIVSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Echinococcus granulosus	transcription factor collier	0.0123	0.0203	0.0236
Echinococcus granulosus	tyrosine protein kinase Src64B	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Schistosoma mansoni	hypothetical protein	0.0064	0.0065	0.0057
Echinococcus granulosus	tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Schistosoma mansoni	hypothetical protein	0.0064	0.0065	0.0057
Schistosoma mansoni	semaphorin 5-related	0.028	0.0572	0.0565
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0081	0.0105	0.0099
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0697	0.155	0.1545
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	tyrosine protein kinase csk	0.004	0.0008	0.0002
Trypanosoma brucei	PH domain containing protein, putative	0.0064	0.0065	0.5844
Entamoeba histolytica	ARF GTPase activating protein, putative	0.0064	0.0065	0.0369
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0081	0.0105	0.0631
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine kinase	0.004	0.0008	0.0002
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0064	0.0065	0.0059
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Schistosoma mansoni	growth factor receptor-bound protein	0.0064	0.0065	0.0057
Echinococcus multilocularis	tyrosine kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0008	0.0052
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus granulosus	collagen type iv alpha 3 binding protein	0.0064	0.0065	0.007
Loa Loa (eye worm)	TK/EGFR protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.028	0.0572	0.0567
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Schistosoma mansoni	dynamin	0.0064	0.0065	0.0057
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.004	0.0008	0.0002
Brugia malayi	serine/threonine-protein kinase 6	0.0074	0.0089	0.0083
Trichomonas vaginalis	centaurin alpha, putative	0.0064	0.0065	0.0419
Plasmodium vivax	calcium-dependent protein kinase 7, putative	0.0081	0.0105	1
Schistosoma mansoni	centaurin alpha	0.0064	0.0065	0.0057
Echinococcus multilocularis	tyrosine protein kinase pr2	0.004	0.0008	0.0002
Loa Loa (eye worm)	RhoGEF domain-containing protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trypanosoma cruzi	hypothetical protein	0.0064	0.0065	0.5844
Trichomonas vaginalis	ribosomal protein S6 kinase, 90kD, polypeptide, putative	0.0081	0.0105	0.068
Echinococcus granulosus	retinal guanylyl cyclase 2	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	regulator of G protein signaling 3	0.0697	0.155	0.1847
Echinococcus granulosus	type II inositol 34 bisphosphate 4 phosphatase	0.0064	0.0065	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Echinococcus multilocularis	tyrosine protein kinase shark	0.004	0.0008	0.0002
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.004	0.0008	0.0002
Onchocerca volvulus	Protein melted homolog	0.0064	0.0065	0.0392
Toxoplasma gondii	AtPH1 family protein	0.0064	0.0065	0.5844
Trichomonas vaginalis	conserved hypothetical protein	0.0123	0.0203	0.1309
Echinococcus multilocularis	Oxysterol binding protein 11	0.0064	0.0065	0.007
Loa Loa (eye worm)	SRC-1	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0081	0.0105	1
Trichomonas vaginalis	guanyl-nucleotide exchange factor, putative	0.0064	0.0065	0.0419
Schistosoma mansoni	guanyl-nucleotide exchange factor	0.0064	0.0065	0.0057
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0064	0.0065	0.5844
Echinococcus multilocularis	dynamin 1	0.0064	0.0065	0.007
Trypanosoma cruzi	aurora B kinase, putative	0.0074	0.0089	0.8276
Schistosoma mansoni	zinc finger protein	0.0064	0.0065	0.0057
Loa Loa (eye worm)	TK/ROR protein kinase	0.004	0.0008	0.0002
Echinococcus granulosus	arf GAP with coiled coil ANK repeat and PH	0.0064	0.0065	0.007
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trypanosoma brucei	serine/threonine-protein kinase NrkA	0.0081	0.0105	1
Echinococcus granulosus	dynamin 1	0.0064	0.0065	0.007
Loa Loa (eye worm)	rho-GTPase-activating	0.0064	0.0065	0.0059
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0081	0.0105	0.0631
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.0074	0.0089	0.8276
Schistosoma mansoni	serine/threonine-protein kinase	0.0081	0.0105	0.0097
Leishmania major	hypothetical protein, conserved	0.0064	0.0065	0.5844
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.004	0.0008	0.0002
Schistosoma mansoni	protein kinase	0.0057	0.0048	0.004
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.004	0.0008	0.0052
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Echinococcus multilocularis	Ras associated and pleckstrin y	0.0064	0.0065	0.007
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0064	0.0065	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	hypothetical protein	0.028	0.0572	0.0567
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0074	0.0089	0.0522
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	Pleckstrin domain containing protein family B	0.0064	0.0065	0.007
Brugia malayi	TBC domain containing protein	0.0064	0.0065	0.0059
Echinococcus granulosus	Pleckstrin y	0.0064	0.0065	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Loa Loa (eye worm)	hypothetical protein	0.0697	0.155	0.1545
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.0074	0.0089	0.0099
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0008	0.0052
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Onchocerca volvulus	outspread protein homolog	0.0064	0.0065	0.0392
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0064	0.0065	0.0369
Echinococcus granulosus	Regulator of G protein signaling 20	0.0697	0.155	0.1847
Echinococcus granulosus	regulator of G protein signaling 3	0.0697	0.155	0.1847
Echinococcus granulosus	oxysterol binding protein 1	0.0064	0.0065	0.007
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0123	0.0203	0.1309
Loa Loa (eye worm)	hypothetical protein	0.0658	0.1458	0.1453
Echinococcus granulosus	tyrosine protein kinase HCK	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	tyrosine protein kinase HCK	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0697	0.155	1
Brugia malayi	hypothetical protein	0.028	0.0572	0.0567
Trichomonas vaginalis	conserved hypothetical protein	0.0123	0.0203	0.1309
Giardia lamblia	Aurora kinase	0.0074	0.0089	1
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0123	0.0203	0.1309
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Entamoeba histolytica	hypothetical protein	0.0081	0.0105	0.0631
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0697	0.155	1
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Onchocerca volvulus		0.0064	0.0065	0.0392
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Plasmodium falciparum	oxysterol-binding protein, putative	0.0064	0.0065	0.5844
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0081	0.0105	0.0631
Echinococcus multilocularis	FL cytokine receptor	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase Srms	0.004	0.0008	0.0002
Entamoeba histolytica	p21-activated kinase	0.0081	0.0105	0.0631
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Onchocerca volvulus		0.0064	0.0065	0.0392
Schistosoma mansoni	regulator of G protein signaling	0.0697	0.155	0.1543
Trypanosoma cruzi	hypothetical protein	0.0064	0.0065	0.5844
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Echinococcus granulosus	regulator of G protein signaling 3	0.0697	0.155	0.1847
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0081	0.0105	0.0631
Echinococcus granulosus	defective proboscis extension response	0.0047	0.0026	0.0024
Loa Loa (eye worm)	protein kinase domain-containing protein	0.004	0.0008	0.0002
Leishmania major	hypothetical protein, conserved	0.0064	0.0065	0.5844
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Trichomonas vaginalis	conserved hypothetical protein	0.0697	0.155	1
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0008	0.0052
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.004	0.0008	0.0052
Entamoeba histolytica	hypothetical protein	0.0064	0.0065	0.0369
Echinococcus multilocularis	aurora kinase A	0.0074	0.0089	0.0099
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0087	0.0119	0.0113
Brugia malayi	Syntrophin-1	0.0064	0.0065	0.0059
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.004	0.0008	0.0002
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Entamoeba histolytica	hypothetical protein	0.0697	0.155	1
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Schistosoma mansoni	plexin	0.0378	0.0801	0.0793
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	raf serine:threonine protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Entamoeba histolytica	protein kinase, putative	0.0081	0.0105	0.0631
Plasmodium falciparum	protein kinase, putative	0.0057	0.0048	0.4156
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Brugia malayi	serine/threonine kinase 12	0.0074	0.0089	0.0083
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Schistosoma mansoni	rho gtpase activating protein	0.0064	0.0065	0.0057
Echinococcus granulosus	tyrosine protein kinase csk	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Echinococcus multilocularis	oxysterol binding protein 1	0.0064	0.0065	0.007
Echinococcus multilocularis	pleckstrin y domain containing family A	0.0064	0.0065	0.007
Echinococcus multilocularis	protein tyrosine kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0008	0.0052
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus multilocularis	tyrosine protein kinase csk	0.004	0.0008	0.0002
Echinococcus granulosus	regulator of G protein signaling 7	0.0697	0.155	0.1847
Echinococcus multilocularis	beta 1 syntrophin	0.0064	0.0065	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Brugia malayi	SRC-1	0.004	0.0008	0.0002
Echinococcus multilocularis	expressed protein	0.0697	0.155	0.1847
Brugia malayi	Guanylyl cyclase protein 23	0.004	0.0008	0.0002
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0089	0.0522
Brugia malayi	Furin-like cysteine rich region family protein	0.004	0.0008	0.0002
Trypanosoma cruzi	PH domain containing protein, putative	0.0064	0.0065	0.5844
Trypanosoma brucei	Serine/threonine-protein kinase NEK21, putative	0.0081	0.0105	1
Trichomonas vaginalis	CAMK family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	RGC/RGC protein kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.004	0.0008	0.0002
Schistosoma mansoni	vesicular amine transporter	0.005	0.0032	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0123	0.0203	0.1309
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.004	0.0008	0.0002
Trypanosoma brucei	NEK family Serine/threonine-protein kinase, putative	0.0081	0.0105	1
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Entamoeba histolytica	PH domain containing protein	0.0064	0.0065	0.0369
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.004	0.0008	0.0002
Echinococcus granulosus	activated cdc42 kinase 1	0.004	0.0008	0.0002
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0064	0.0065	0.5844
Echinococcus granulosus	calcium dependent secretion activator 1	0.0064	0.0065	0.007
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.004	0.0008	0.0052
Schistosoma mansoni	serine/threonine protein kinase	0.3296	0.7645	0.7643
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	Pleckstrin y	0.0064	0.0065	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0123	0.0203	0.1309
Echinococcus multilocularis	DCC interacting protein 13 beta	0.0064	0.0065	0.007
Echinococcus granulosus	Oxysterol binding protein 11	0.0064	0.0065	0.007
Schistosoma mansoni	voltage-gated potassium channel	0.0042	0.0014	0.0006
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0037	0.0031
Brugia malayi	Cadps2 protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Toxoplasma gondii	hypothetical protein	0.0064	0.0065	0.5844
Brugia malayi	serine/threonine protein kinase 6	0.0074	0.0089	0.0083
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus granulosus	tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Echinococcus multilocularis	Arf GAP and Pleckstrin domain containing protein	0.0064	0.0065	0.007
Brugia malayi	Variant SH3 domain containing protein	0.0064	0.0065	0.0059
Plasmodium vivax	oxysterol-binding protein/PH domain containing protein	0.0064	0.0065	0.5844
Brugia malayi	Protein kinase domain containing protein	0.0081	0.0105	0.0099
Schistosoma mansoni	hypothetical protein	0.028	0.0572	0.0565
Echinococcus granulosus	kinase suppressor of Ras 1	0.004	0.0008	0.0002
Plasmodium falciparum	acylated pleckstrin-homology domain-containing protein, putative	0.0064	0.0065	0.5844
Loa Loa (eye worm)	TK/FAK protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	oxysterol binding protein	0.0064	0.0065	0.0059
Brugia malayi	Dynamin	0.0064	0.0065	0.0059
Schistosoma mansoni	rhogef and pleckstrin domain protein	0.0064	0.0065	0.0057
Echinococcus granulosus	Pleckstrin y	0.0064	0.0065	0.007
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0057	0.0048	0.0051
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0081	0.0105	0.0631
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.004	0.0008	0.0002
Brugia malayi	Immunoglobulin I-set domain containing protein	0.004	0.0008	0.0002
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0057	0.0048	0.4156
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	hypothetical protein	0.0697	0.155	0.1545
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.2599	0.601	0.7183
Schistosoma mansoni	dynamin	0.0064	0.0065	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Entamoeba histolytica	PH domain containing protein	0.0064	0.0065	0.0369
Schistosoma mansoni	regulator of G protein signaling	0.0697	0.155	0.1543
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0064	0.0065	0.5844
Loa Loa (eye worm)	hypothetical protein	0.0697	0.155	0.1545
Echinococcus granulosus	aurora kinase A	0.0074	0.0089	0.0099
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Onchocerca volvulus	Abnormal cell migration protein 10 homolog	0.0064	0.0065	0.0392
Echinococcus multilocularis	c src tyrosine kinase	0.004	0.0008	0.0002
Brugia malayi	hypothetical protein	0.0697	0.155	0.1545
Trypanosoma cruzi	Protein kinase B	0.0081	0.0105	1
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.3603	0.8365	1
Schistosoma mansoni	regulator of G protein signaling	0.0697	0.155	0.1543
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0008	0.0052
Echinococcus granulosus	semaphorin 5B	0.028	0.0572	0.0677
Echinococcus granulosus	FERM and pleckstrin domain containing protein	0.0064	0.0065	0.007
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0047	0.0026	0.0024
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0057	0.0048	0.4156
Plasmodium falciparum	PH domain-containing protein, putative	0.0064	0.0065	0.5844
Trypanosoma cruzi	hypothetical protein	0.0064	0.0065	0.5844
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	Pleckstrin y	0.0064	0.0065	0.007
Trypanosoma cruzi	NIMA-related kinase, putative	0.0081	0.0105	1
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Schistosoma mansoni	syntrophin	0.0064	0.0065	0.0057
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.028	0.0572	0.0567
Loa Loa (eye worm)	hypothetical protein	0.0123	0.0203	0.0197
Trichomonas vaginalis	TK family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	Pleckstrin y	0.0064	0.0065	0.007
Echinococcus multilocularis	neuroglian	0.0047	0.0026	0.0024
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Echinococcus granulosus	protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Schistosoma mansoni	axis inhibition protein axin	0.0697	0.155	0.1543
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Trypanosoma cruzi	hypothetical protein	0.0064	0.0065	0.5844
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	DNA-binding protein LAG-1	0.0123	0.0203	0.0197
Echinococcus multilocularis	transfer RNA-Thr	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	oxysterol binding protein 9	0.0064	0.0065	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Toxoplasma gondii	calcium dependent protein kinase CDPK7	0.0081	0.0105	1
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0697	0.155	0.1545
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	PXA domain-containing protein	0.0697	0.155	0.1545
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	TK/Met protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0087	0.0119	0.0113
Loa Loa (eye worm)	hypothetical protein	0.028	0.0572	0.0567
Echinococcus granulosus	tyrosine protein kinase ABL1	0.004	0.0008	0.0002
Echinococcus granulosus	beta-adrenergic receptor kinase	0.3296	0.7645	0.9139
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	centaurin/arf, putative	0.0064	0.0065	0.0419
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	cytohesin 3	0.0064	0.0065	0.0059
Schistosoma mansoni	voltage-gated potassium channel	0.0042	0.0014	0.0006
Trichomonas vaginalis	AGC family protein kinase	0.0074	0.0089	0.0571
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.028	0.0572	0.0567
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Brugia malayi	Dynamin	0.0064	0.0065	0.0059
Echinococcus multilocularis	Immunoglobulin	0.0047	0.0026	0.0024
Onchocerca volvulus	Putative zinc finger protein	0.0064	0.0065	0.0392
Trypanosoma brucei	protein kinase, putative	0.0081	0.0105	1
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.004	0.0008	0.0002
Trichomonas vaginalis	STE family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	activin receptor type	0.0057	0.0048	0.0051
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0697	0.155	0.1545
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0081	0.0105	1
Leishmania major	protein kinase, putative	0.0081	0.0105	1
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase csk	0.004	0.0008	0.0002
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.004	0.0008	0.0002
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	PH domain-containing protein	0.0064	0.0065	0.0059
Echinococcus granulosus	serine/threonine protein kinase	0.0081	0.0105	0.0119
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Schistosoma mansoni	vav2	0.0064	0.0065	0.0057
Brugia malayi	regulator of G-protein signaling egl-10	0.0697	0.155	0.1545
Entamoeba histolytica	protein kinase domain containing protein	0.0057	0.0048	0.0262
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.004	0.0008	0.0052
Echinococcus granulosus	Rho GTPase activating protein 24	0.0064	0.0065	0.007
Echinococcus multilocularis	Pleckstrin y	0.0064	0.0065	0.007
Echinococcus multilocularis	arf GAP with coiled coil, ANK repeat and PH	0.0064	0.0065	0.007
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Plasmodium falciparum	phosphatidylinositol transfer protein, putative	0.0064	0.0065	0.5844
Schistosoma mansoni	protein kinase	0.0057	0.0048	0.004
Leishmania major	folate/biopterin transporter, putative	0.0081	0.0105	1
Echinococcus multilocularis	semaphorin 5B	0.028	0.0572	0.0677
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Brugia malayi	Pleckstrin Homology Domain	0.0064	0.0065	0.0059
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Schistosoma mansoni	myotubularin-related protein	0.0064	0.0065	0.0057
Schistosoma mansoni	protein kinase	0.0074	0.0089	0.0081
Trypanosoma cruzi	PH domain containing protein, putative	0.0064	0.0065	0.5844
Entamoeba histolytica	protein kinase, putative	0.0081	0.0105	0.0631
Trichomonas vaginalis	conserved hypothetical protein	0.0697	0.155	1
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0064	0.0065	0.0059
Echinococcus granulosus	insulin receptor	0.004	0.0008	0.0002
Schistosoma mansoni	serine/threonine-protein kinase	0.0081	0.0105	0.0097
Echinococcus multilocularis	regulator of G protein signaling	0.0697	0.155	0.1847
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Schistosoma mansoni	serine/threonine protein kinase	0.0074	0.0089	0.0081
Echinococcus multilocularis	tyrosine protein kinase Srms	0.004	0.0008	0.0002
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0064	0.0065	0.0059
Trichomonas vaginalis	AGC family protein kinase	0.0074	0.0089	0.0571
Trypanosoma cruzi	NEK family Serine/threonine-protein kinase, putative	0.0081	0.0105	1
Loa Loa (eye worm)	sema domain-containing protein	0.028	0.0572	0.0567
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0026	0.002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	natriuretic peptide receptor 1	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0064	0.0065	0.007
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Entamoeba histolytica	pleckstrin homology (PH) domain containing protein	0.0064	0.0065	0.0369
Entamoeba histolytica	protein kinase , putative	0.0074	0.0089	0.0522
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Echinococcus granulosus	activated cdc42 kinase 1	0.004	0.0008	0.0002
Echinococcus granulosus	GRB2 associated binding protein 3	0.0064	0.0065	0.007
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Brugia malayi	PXA domain containing protein	0.0697	0.155	0.1545
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Brugia malayi	Sema domain containing protein	0.028	0.0572	0.0567
Brugia malayi	hypothetical protein	0.004	0.0008	0.0002
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0057	0.0048	0.4156
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0064	0.0065	0.0419
Trichomonas vaginalis	conserved hypothetical protein	0.0123	0.0203	0.1309
Trypanosoma cruzi	hypothetical protein	0.0064	0.0065	0.5844
Echinococcus multilocularis	actin binding protein anillin	0.0064	0.0065	0.007
Brugia malayi	bone morphogenetic protein type 1 receptor	0.004	0.0008	0.0002
Brugia malayi	Fibronectin type III domain containing protein	0.0052	0.0037	0.0031
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	TK/RYK protein kinase	0.004	0.0008	0.0002
Entamoeba histolytica	protein kinase domain containing protein	0.0163	0.0296	0.1868
Onchocerca volvulus		0.0064	0.0065	0.0392
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Trypanosoma cruzi	serine/threonine-protein kinase NRKB, putative	0.0081	0.0105	1
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus multilocularis	activated cdc42 kinase 1	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.023	0.0454	0.0449
Echinococcus granulosus	roundabout 2	0.0052	0.0037	0.0038
Loa Loa (eye worm)	hypothetical protein	0.0123	0.0203	0.0197
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Leishmania major	protein kinase, putative	0.0081	0.0105	1
Trypanosoma brucei	aurora B kinase	0.0074	0.0089	0.8276
Entamoeba histolytica	hypothetical protein	0.0123	0.0203	0.1263
Entamoeba histolytica	hypothetical protein	0.0064	0.0065	0.0369
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase csk	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Brugia malayi	IPT/TIG domain containing protein	0.0123	0.0203	0.0197
Echinococcus granulosus	beta 1 syntrophin	0.0064	0.0065	0.007
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0081	0.0105	1
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0123	0.0203	0.1309
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0045	0.0019	0.0016
Echinococcus multilocularis	regulator of G protein signaling 7	0.0697	0.155	0.1847
Toxoplasma gondii	protein kinase domain-containing protein	0.0081	0.0105	1
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	RGC/RGC protein kinase	0.004	0.0008	0.0002
Trypanosoma cruzi	rac serine-threonine kinase, putative	0.0081	0.0105	1
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.004	0.0008	0.0002
Echinococcus multilocularis	integrin linked protein kinase	0.004	0.0008	0.0002
Echinococcus granulosus	c src tyrosine kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	tyrosine protein kinase csk	0.004	0.0008	0.0002
Toxoplasma gondii	phosphatidylinositol transfer protein	0.0064	0.0065	0.5844
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0081	0.0105	0.0631
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0052	0.0037	0.0031
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	oxysterol binding protein 3	0.0064	0.0065	0.007
Brugia malayi	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus granulosus	tyrosine kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0026	0.002
Brugia malayi	hypothetical protein	0.0052	0.0037	0.0031
Plasmodium vivax	PH domain containing protein	0.0064	0.0065	0.5844
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Entamoeba histolytica	PH domain containing protein	0.0064	0.0065	0.0369
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Echinococcus granulosus	Immunoglobulin	0.0047	0.0026	0.0024
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Entamoeba histolytica	hypothetical protein	0.0697	0.155	1
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	hypothetical protein	0.0697	0.155	0.1545
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	retinal guanylyl cyclase 2	0.004	0.0008	0.0002
Brugia malayi	ephrin receptor 1 precursor	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0026	0.002
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine kinase	0.004	0.0008	0.0002
Leishmania major	protein kinase, putative	0.0057	0.0048	0.4156
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	serine/threonine protein kinase	0.004	0.0008	0.0002
Entamoeba histolytica	protein kinase, putative	0.0081	0.0105	0.0631
Brugia malayi	plexin A	0.0781	0.1746	0.1741
Loa Loa (eye worm)	AUR protein kinase	0.0074	0.0089	0.0083
Brugia malayi	Receptor family ligand binding region containing protein	0.004	0.0008	0.0002
Brugia malayi	GTPase-activator protein for Ras-like GTPase containing protein	0.0064	0.0065	0.0059
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.0064	0.0065	0.0419
Echinococcus multilocularis	tyrosine protein kinase Blk	0.004	0.0008	0.0002
Brugia malayi	Plekhf2 protein	0.0064	0.0065	0.0059
Schistosoma mansoni	oxysterol-binding protein 1	0.0064	0.0065	0.0057
Schistosoma mansoni	hypothetical protein	0.0378	0.0801	0.0793
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.3603	0.8365	1
Onchocerca volvulus		0.0064	0.0065	0.0392
Echinococcus granulosus	pdz domain containing protein	0.0064	0.0065	0.007
Schistosoma mansoni	nephrin	0.0052	0.0037	0.0029
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0045	0.0019	0.0016
Schistosoma mansoni	fibrocystin l	0.0123	0.0203	0.0195
Loa Loa (eye worm)	syntrophin-1	0.0064	0.0065	0.0059
Trichomonas vaginalis	protein tyrosine kinase, putative	0.004	0.0008	0.0052
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.004	0.0008	0.0002
Entamoeba histolytica	hypothetical protein	0.0123	0.0203	0.1263
Brugia malayi	hypothetical protein	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase shark	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus granulosus	tyrosine protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	hypothetical protein	0.0378	0.0801	0.0795
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	tyrosine protein kinase Blk	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Entamoeba histolytica	tyrosin kinase, putative	0.0163	0.0296	0.1868
Echinococcus multilocularis	protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	centaurin beta, putative	0.0064	0.0065	0.0419
Echinococcus multilocularis	kinase suppressor of Ras 1	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Entamoeba histolytica	hypothetical protein	0.0081	0.0105	0.0631
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0074	0.0089	0.0522
Echinococcus multilocularis	ephrin type A receptor 4 A	0.004	0.0008	0.0002
Loa Loa (eye worm)	AUR protein kinase	0.0074	0.0089	0.0083
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	TK/ALK protein kinase	0.0301	0.0621	0.0615
Schistosoma mansoni	regulator of G protein signaling	0.0697	0.155	0.1543
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	exocyst complex component 2	0.0123	0.0203	0.0236
Leishmania major	rac serine-threonine kinase, putative,protein kinase, putative	0.0081	0.0105	1
Echinococcus multilocularis	cytohesin 1	0.0064	0.0065	0.007
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Echinococcus multilocularis	transcription factor collier	0.0123	0.0203	0.0236
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.004	0.0008	0.0002
Onchocerca volvulus		0.028	0.0572	0.3891
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Echinococcus granulosus	myotubularin protein 13	0.0064	0.0065	0.007
Echinococcus multilocularis	GRB2 associated binding protein 3	0.0064	0.0065	0.007
Echinococcus granulosus	G protein coupled receptor kinase 1	0.2599	0.601	0.7183
Onchocerca volvulus		0.0064	0.0065	0.0392
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0064	0.0065	0.0419
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Brugia malayi	Plexin repeat family protein	0.0658	0.1458	0.1453
Echinococcus granulosus	regulator of G protein signaling 7	0.0697	0.155	0.1847
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus granulosus	ephrin type A receptor 4 A	0.004	0.0008	0.0002
Brugia malayi	Protein kinase domain containing protein	0.0301	0.0621	0.0616
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0697	0.155	0.1847
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.004	0.0008	0.0002
Entamoeba histolytica	protein kinase, putative	0.0081	0.0105	0.0631
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0074	0.0089	0.8276
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Trypanosoma cruzi	ADP-ribosylation factor family, putative	0.0064	0.0065	0.5844
Trypanosoma brucei	serine/threonine-protein kinase NRKB, putative	0.0081	0.0105	1
Trichomonas vaginalis	alpha chimerin, putative	0.0064	0.0065	0.0419
Trypanosoma cruzi	Serine/threonine-protein kinase NEK17, putative	0.0081	0.0105	1
Entamoeba histolytica	protein kinase, putative	0.0081	0.0105	0.0631
Echinococcus granulosus	DCC interacting protein 13 beta	0.0064	0.0065	0.007
Schistosoma mansoni	hypothetical protein	0.0064	0.0065	0.0057
Echinococcus granulosus	oxysterol binding protein 9	0.0064	0.0065	0.007
Schistosoma mansoni	hypothetical protein	0.028	0.0572	0.0565
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	RGS-3 protein	0.0697	0.155	0.1545
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Echinococcus multilocularis	Rho GTPase activating protein 24	0.0064	0.0065	0.007
Echinococcus multilocularis	ras specific guanine nucleotide releasing factor	0.0064	0.0065	0.007
Schistosoma mansoni	z-protein (S1r protein)	0.0697	0.155	0.1543
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.004	0.0008	0.0002
Echinococcus granulosus	protein tyrosine kinase	0.004	0.0008	0.0002
Echinococcus granulosus	Arf GAP and Pleckstrin domain containing protein	0.0064	0.0065	0.007
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.004	0.0008	0.0002
Echinococcus granulosus	oxysterol binding protein 3	0.0064	0.0065	0.007
Brugia malayi	Raf kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	heat shock protein 70	0.004	0.0008	0.0002
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0064	0.0065	0.0369
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Schistosoma mansoni	regulator of G protein signaling	0.0697	0.155	0.1543
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	regulator of G protein signaling 7	0.0697	0.155	0.1847
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Entamoeba histolytica	protein kinase, putative	0.0081	0.0105	0.0631
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Echinococcus multilocularis	Immunoglobulin	0.0047	0.0026	0.0024
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0057	0.0048	0.4156
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK/ACK protein kinase	0.004	0.0008	0.0002
Brugia malayi	Tyrosine-protein kinase PR2	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Loa Loa (eye worm)	plexin A	0.0781	0.1746	0.1741
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0057	0.0048	0.0051
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Plasmodium falciparum	calcium-dependent protein kinase 7	0.0081	0.0105	1
Echinococcus multilocularis	roundabout 2	0.0052	0.0037	0.0038
Schistosoma mansoni	ephrin receptor	0.0045	0.0019	0.0011
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0064	0.0065	0.007
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.004	0.0008	0.0002
Echinococcus multilocularis	myotubularin protein 13	0.0064	0.0065	0.007
Brugia malayi	SH2 domain containing protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0026	0.002
Schistosoma mansoni	hypothetical protein	0.0064	0.0065	0.0057
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	hypothetical protein	0.028	0.0572	0.0567
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0064	0.0065	0.0057
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0697	0.155	0.1543
Echinococcus multilocularis	calcium dependent secretion activator 1	0.0064	0.0065	0.007
Echinococcus granulosus	activin receptor type	0.0057	0.0048	0.0051
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus multilocularis	protein KINase family member (kin 25)	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0697	0.155	0.1847
Trypanosoma cruzi	hypothetical protein	0.0064	0.0065	0.5844
Echinococcus granulosus	axis inhibition protein axin	0.0697	0.155	0.1847
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0697	0.155	0.1543
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0064	0.0065	0.0369
Schistosoma mansoni	hypothetical protein	0.0123	0.0203	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Echinococcus multilocularis	receptor type guanylyl cyclase	0.004	0.0008	0.0002
Schistosoma mansoni	goodpasture antigen-binding protein	0.0064	0.0065	0.0057
Trichomonas vaginalis	conserved hypothetical protein	0.0697	0.155	1
Echinococcus granulosus	integrin linked protein kinase	0.004	0.0008	0.0002
Schistosoma mansoni	protein kinase	0.0057	0.0048	0.004
Schistosoma mansoni	oxysterol-binding protein 1	0.0064	0.0065	0.0057
Echinococcus multilocularis	natriuretic peptide receptor 1	0.004	0.0008	0.0002
Echinococcus granulosus	raf serine:threonine protein kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	tyrosine protein kinase csk	0.004	0.0008	0.0002
Entamoeba histolytica	hypothetical protein	0.0697	0.155	1
Entamoeba histolytica	cell surface protease gp63, putative	0.0123	0.0203	0.1263
Trichomonas vaginalis	development and differentiation-enhancing factor, ddef, putative	0.0064	0.0065	0.0419
Trichomonas vaginalis	centaurin gamma, putative	0.0064	0.0065	0.0419
Entamoeba histolytica	hypothetical protein	0.0123	0.0203	0.1263
Echinococcus granulosus	tyrosine protein kinase Src42A	0.004	0.0008	0.0002
Trichomonas vaginalis	protein kinase atn1, putative	0.004	0.0008	0.0052
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.3603	0.8365	0.8364
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.0074	0.0089	0.0099
Brugia malayi	GTP-ase activating protein for Arf containing protein	0.0064	0.0065	0.0059
Entamoeba histolytica	hypothetical protein	0.0064	0.0065	0.0369
Schistosoma mansoni	serine/threonine protein kinase	0.3296	0.7645	0.7643
Echinococcus multilocularis	epidermal growth factor receptor	0.004	0.0008	0.0002
Echinococcus granulosus	fibroblast growth factor receptor 4	0.004	0.0008	0.0002
Schistosoma mansoni	goodpasture antigen-binding protein	0.0064	0.0065	0.0057
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase pr2	0.004	0.0008	0.0002
Trichomonas vaginalis	protein transport protein sec7, putative	0.0064	0.0065	0.0419
Loa Loa (eye worm)	RGC/RGC protein kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	tyrosine kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	insulin receptor	0.004	0.0008	0.0002
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.004	0.0008	0.0002
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0047	0.0026	0.0018
Schistosoma mansoni	axis inhibition protein axin	0.0697	0.155	0.1543
Brugia malayi	Oxysterol binding protein	0.0064	0.0065	0.0059
Brugia malayi	Sema domain containing protein	0.028	0.0572	0.0567
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	sema domain-containing protein	0.028	0.0572	0.0567
Schistosoma mansoni	hypothetical protein	0.0123	0.0203	0.0195
Entamoeba histolytica	hypothetical protein	0.0123	0.0203	0.1263
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.004	0.0008	0.0002
Echinococcus multilocularis	rac serine:threonine kinase	0.0081	0.0105	0.0119
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0697	0.155	0.1847
Brugia malayi	Uncoordinated protein 104	0.0064	0.0065	0.0059
Loa Loa (eye worm)	Plekhf2 protein	0.0064	0.0065	0.0059
Brugia malayi	A-kinase anchor protein 10, precursor	0.0697	0.155	0.1545
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Toxoplasma gondii	Oxysterol-binding protein	0.0064	0.0065	0.5844
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Brugia malayi	probable spectrin beta chain	0.0064	0.0065	0.0059
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	retinal guanylyl cyclase 2	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.004	0.0008	0.0002
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0064	0.0065	0.0419
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0064	0.0065	0.5844
Onchocerca volvulus		0.0064	0.0065	0.0392
Echinococcus granulosus	pleckstrin y domain containing family A	0.0064	0.0065	0.007
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	tyrosine protein kinase Fyn	0.004	0.0008	0.0002
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0037	0.0031
Brugia malayi	Tyrosine-protein kinase abl-1	0.004	0.0008	0.0002
Echinococcus granulosus	neuroglian	0.0047	0.0026	0.0024
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Brugia malayi	integrin-linked kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.004	0.0008	0.0002
Leishmania major	serine/threonine-protein kinase a, putative	0.0081	0.0105	1
Echinococcus multilocularis	tyrosine protein kinase	0.004	0.0008	0.0002
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0047	0.0026	0.0018
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0047	0.0026	0.0024
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0074	0.0089	0.0522
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.004	0.0008	0.0002
Entamoeba histolytica	hypothetical protein	0.0064	0.0065	0.0369
Echinococcus multilocularis	exocyst complex component 2	0.0123	0.0203	0.0236
Loa Loa (eye worm)	TK/ABL protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0008	0.0052
Brugia malayi	hypothetical protein	0.028	0.0572	0.0567
Trichomonas vaginalis	hypothetical protein	0.0064	0.0065	0.0419
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.004	0.0008	0.0002
Entamoeba histolytica	Rho guanine nucleotide exchange factor, putative	0.0064	0.0065	0.0369
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.004	0.0008	0.0002
Echinococcus multilocularis	FERM and pleckstrin domain containing protein	0.0064	0.0065	0.007
Echinococcus multilocularis	Pleckstrin domain containing protein, family B	0.0064	0.0065	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0123	0.0203	0.0197
Echinococcus granulosus	expressed protein	0.0697	0.155	0.1847
Echinococcus multilocularis	pdz domain containing protein	0.0064	0.0065	0.007
Trypanosoma cruzi	phosphatidylinositol-4-phosphate 5-kinase, putative	0.0064	0.0065	0.5844
Schistosoma mansoni	cell adhesion molecule	0.0052	0.0037	0.0029
Brugia malayi	Variant SH3 domain containing protein	0.0064	0.0065	0.0059
Echinococcus multilocularis	plexin a4	0.0781	0.1746	0.2082
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Echinococcus granulosus	receptor type guanylyl cyclase	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0697	0.155	1
Trichomonas vaginalis	protein transport protein sec7, putative	0.0064	0.0065	0.0419
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK/CSK protein kinase	0.004	0.0008	0.0002
Schistosoma mansoni	phosphoinositol 4-phosphate adaptor protein	0.0064	0.0065	0.0057
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Brugia malayi	protein-tyrosine kinase	0.004	0.0008	0.0002
Schistosoma mansoni	hypothetical protein	0.0064	0.0065	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0026	0.002
Echinococcus granulosus	epidermal growth factor receptor	0.004	0.0008	0.0002
Trichomonas vaginalis	AGC family protein kinase	0.0074	0.0089	0.0571
Echinococcus multilocularis	collagen type iv alpha 3 binding protein	0.0064	0.0065	0.007
Trichomonas vaginalis	3-phosphoinositide dependent protein kinase-1, putative	0.0081	0.0105	0.068
Echinococcus granulosus	plexin a4	0.0781	0.1746	0.2082
Entamoeba histolytica	protein kinase, putative	0.0074	0.0089	0.0522
Trichomonas vaginalis	centaurin/arf, putative	0.0064	0.0065	0.0419
Onchocerca volvulus	Putative neuronal RhoA GEF protein	0.0064	0.0065	0.0392
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.004	0.0008	0.0002
Echinococcus multilocularis	axis inhibition protein axin	0.0697	0.155	0.1847
Schistosoma mansoni	zinc finger protein	0.0064	0.0065	0.0057
Trypanosoma cruzi	hypothetical protein	0.0064	0.0065	0.5844
Echinococcus multilocularis	type II inositol 3,4 bisphosphate 4 phosphatase	0.0064	0.0065	0.007
Echinococcus granulosus	axis inhibition protein axin	0.0697	0.155	0.1847
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.3603	0.8365	0.8364
Brugia malayi	hypothetical protein	0.0697	0.155	0.1545
Trichomonas vaginalis	conserved hypothetical protein	0.0064	0.0065	0.0419
Trypanosoma cruzi	NIMA-related kinase, putative	0.0081	0.0105	1
Entamoeba histolytica	protein kinase, putative	0.0074	0.0089	0.0522
Entamoeba histolytica	hypothetical protein, conserved domain containing	0.0064	0.0065	0.0369
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0057	0.0048	0.0051
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	TK/INSR protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0123	0.0203	0.1309
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	GTP-ase activating protein for Arf containing protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	hypothetical protein	0.0123	0.0203	0.0197
Echinococcus multilocularis	regulator of G protein signaling 3	0.0697	0.155	0.1847
Trichomonas vaginalis	Clan MA, family M8, leishmanolysin-like metallopeptidase	0.0123	0.0203	0.1309
Brugia malayi	PH domain containing protein	0.0064	0.0065	0.0059
Echinococcus multilocularis	hypothetical protein	0.028	0.0572	0.0677
Echinococcus multilocularis	epidermal growth factor receptor	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0008	0.0052
Brugia malayi	PXA domain containing protein	0.0697	0.155	0.1545
Echinococcus multilocularis	beta adrenergic receptor kinase	0.3296	0.7645	0.9139
Echinococcus granulosus	semaphorin 1A	0.028	0.0572	0.0677
Trypanosoma cruzi	PH domain containing protein, putative	0.0064	0.0065	0.5844
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Schistosoma mansoni	plexin	0.0658	0.1458	0.1451
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0697	0.155	0.1543
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0697	0.155	0.1545
Loa Loa (eye worm)	hypothetical protein	0.0697	0.155	0.1545
Brugia malayi	SH2 domain containing protein	0.004	0.0008	0.0002
Leishmania major	protein kinase, putative	0.0074	0.0089	0.8276
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0081	0.0105	1
Loa Loa (eye worm)	uncoordinated protein 104	0.0064	0.0065	0.0059
Entamoeba histolytica	protein kinase, putative	0.0081	0.0105	0.0631
Trichomonas vaginalis	kinesin light chain, putative	0.0064	0.0065	0.0419
Echinococcus granulosus	ras specific guanine nucleotide releasing factor	0.0064	0.0065	0.007
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Trichomonas vaginalis	AGC family protein kinase	0.0074	0.0089	0.0571
Trichomonas vaginalis	conserved hypothetical protein	0.0123	0.0203	0.1309
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0026	0.002
Entamoeba histolytica	hypothetical protein	0.0064	0.0065	0.0369
Echinococcus multilocularis	tyrosine protein kinase Abl	0.004	0.0008	0.0002
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.004	0.0008	0.0002
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.3296	0.7645	0.7644
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Leishmania major	protein kinase, putative,serine/threonine protein kinase, putative	0.0081	0.0105	1
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0037	0.0031
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0697	0.155	1
Loa Loa (eye worm)	hypothetical protein	0.004	0.0008	0.0002
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Brugia malayi	Protein kinase domain containing protein	0.004	0.0008	0.0002
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0081	0.0105	1
Brugia malayi	MAX-1A	0.0064	0.0065	0.0059
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Probable exocyst complex component Sec5	0.0123	0.0203	0.0197
Trypanosoma brucei	protein kinase, putative	0.0057	0.0048	0.4156
Trypanosoma cruzi	Serine/threonine-protein kinase NEK21, putative	0.0081	0.0105	1
Onchocerca volvulus		0.0064	0.0065	0.0392
Echinococcus granulosus	epidermal growth factor receptor	0.004	0.0008	0.0002
Toxoplasma gondii	aurora kinase	0.0074	0.0089	0.8276
Loa Loa (eye worm)	TK/EPH protein kinase	0.004	0.0008	0.0002
Brugia malayi	Cytohesin 3	0.0064	0.0065	0.0059
Brugia malayi	regulator of G-protein signaling rgs-7	0.0697	0.155	0.1545
Loa Loa (eye worm)	RGC/RGC protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	conserved hypothetical protein	0.0123	0.0203	0.1309
Entamoeba histolytica	hypothetical protein, conserved	0.0064	0.0065	0.0369
Echinococcus granulosus	twitchin	0.0065	0.0067	0.0072
Loa Loa (eye worm)	TK protein kinase	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Plasmodium vivax	hypothetical protein, conserved	0.0064	0.0065	0.5844
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Toxoplasma gondii	hypothetical protein	0.0064	0.0065	0.5844
Loa Loa (eye worm)	AUR protein kinase	0.0074	0.0089	0.0083
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.004	0.0008	0.0002
Loa Loa (eye worm)	TK/DDR protein kinase	0.004	0.0008	0.0002
Onchocerca volvulus		0.0658	0.1458	1
Trypanosoma cruzi	PH domain containing protein, putative	0.0064	0.0065	0.5844
Trichomonas vaginalis	AGC family protein kinase	0.0081	0.0105	0.068
Echinococcus granulosus	cytohesin 1	0.0064	0.0065	0.007
Loa Loa (eye worm)	TK/FER protein kinase	0.004	0.0008	0.0002
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052
Brugia malayi	Oxysterol-binding protein	0.0064	0.0065	0.0059
Brugia malayi	hypothetical protein	0.004	0.0008	0.0002
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.3603	0.8365	0.8364
Echinococcus multilocularis	protein kinase	0.004	0.0008	0.0002
Brugia malayi	C-terminal src kinase protein 1	0.004	0.0008	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0064	0.0065	0.0059
Echinococcus multilocularis	axis inhibition protein axin	0.0697	0.155	0.1847
Trichomonas vaginalis	TKL family protein kinase	0.004	0.0008	0.0052

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1739484

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1509298