Detailed information for compound 1510190

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 559.537 | Formula: C22H12Cl2N6S4
  • H donors: 0 H acceptors: 6 LogP: 5.91 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#CC(=C(SCc1nnc(s1)c1ccc(cc1)Cl)SCc1nnc(s1)c1ccc(cc1)Cl)C#N
  • InChi: 1S/C22H12Cl2N6S4/c23-16-5-1-13(2-6-16)20-29-27-18(33-20)11-31-22(15(9-25)10-26)32-12-19-28-30-21(34-19)14-3-7-17(24)8-4-14/h1-8H,11-12H2
  • InChiKey: RUKXJLPLMYOBTQ-UHFFFAOYSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Tyrosine-protein kinase abl-1 0.0043 0.0015 0.0009
Schistosoma mansoni dynamin 0.0065 0.0064 0.005
Schistosoma mansoni myotubularin-related protein 0.0065 0.0064 0.005
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0043 0.0015 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0065 0.0064 0.0058
Brugia malayi hypothetical protein 0.0065 0.0064 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Brugia malayi Sema domain containing protein 0.0299 0.0609 0.0603
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0064 0.5483
Echinococcus multilocularis beta 1 syntrophin 0.0065 0.0064 0.0069
Trichomonas vaginalis hypothetical protein 0.0065 0.0064 0.0413
Echinococcus multilocularis neuroglian 0.0063 0.0062 0.0066
Loa Loa (eye worm) hypothetical protein 0.0703 0.1549 0.1544
Echinococcus granulosus Pleckstrin y 0.0065 0.0064 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis Ras associated and pleckstrin y 0.0065 0.0064 0.0069
Echinococcus multilocularis receptor type guanylyl cyclase 0.0043 0.0015 0.0011
Loa Loa (eye worm) TK/ROR protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0104 0.0583
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0089 0.0083
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Brugia malayi Dynamin 0.0065 0.0064 0.0058
Entamoeba histolytica PH domain containing protein 0.0065 0.0064 0.032
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0043 0.0015 0.0011
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0043 0.0015 0.0011
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0043 0.0015 0.0011
Plasmodium falciparum calcium-dependent protein kinase 7 0.0082 0.0104 1
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0043 0.0015 0.0011
Trypanosoma brucei protein kinase, putative 0.0061 0.0055 0.4517
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus granulosus pleckstrin y domain containing family A 0.0065 0.0064 0.0069
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0082 0.0104 1
Echinococcus multilocularis axis inhibition protein axin 0.0703 0.1549 0.1846
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Echinococcus multilocularis oxysterol binding protein 1 0.0065 0.0064 0.0069
Loa Loa (eye worm) hypothetical protein 0.0299 0.0609 0.0603
Echinococcus granulosus tyrosine protein kinase 0.0043 0.0015 0.0011
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0043 0.0015 0.0011
Trypanosoma cruzi aurora B kinase, putative 0.0075 0.0089 0.827
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0075 0.0089 0.827
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0043 0.0015 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0089 0.0075
Schistosoma mansoni axis inhibition protein axin 0.0703 0.1549 0.1537
Entamoeba histolytica hypothetical protein 0.0065 0.0064 0.032
Leishmania major serine/threonine-protein kinase a, putative 0.0082 0.0104 1
Onchocerca volvulus 0.0065 0.0064 0.032
Entamoeba histolytica protein kinase domain containing protein 0.0174 0.0319 0.1984
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Entamoeba histolytica hypothetical protein 0.0082 0.0104 0.0583
Brugia malayi Immunoglobulin I-set domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0065 0.0064 0.0069
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0043 0.0015 0.0011
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0065 0.0064 0.0413
Trypanosoma cruzi PH domain containing protein, putative 0.0065 0.0064 0.5483
Loa Loa (eye worm) hypothetical protein 0.0063 0.0062 0.0056
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0065 0.0064 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0218 0.141
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0015 0.0096
Entamoeba histolytica hypothetical protein, conserved 0.0065 0.0064 0.032
Schistosoma mansoni syntrophin 0.0065 0.0064 0.005
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0065 0.0064 0.0069
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0299 0.0609 0.0603
Echinococcus multilocularis regulator of G protein signaling 7 0.0703 0.1549 0.1846
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Echinococcus multilocularis protein kinase 0.0043 0.0015 0.0011
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Toxoplasma gondii phosphatidylinositol transfer protein 0.0065 0.0064 0.5483
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0043 0.0015 0.0011
Echinococcus multilocularis protein kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0131 0.0218 0.0213
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Schistosoma mansoni oxysterol-binding protein 1 0.0065 0.0064 0.005
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0026 0.0024
Entamoeba histolytica hypothetical protein 0.0131 0.0218 0.1326
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0082 0.0104 1
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Brugia malayi bone morphogenetic protein type 1 receptor 0.0043 0.0015 0.0009
Echinococcus granulosus expressed protein 0.0703 0.1549 0.1846
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0104 0.0583
Brugia malayi Furin-like cysteine rich region family protein 0.0043 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0131 0.0218 0.0213
Brugia malayi Pleckstrin Homology Domain 0.0065 0.0064 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0068 0.0073 0.0067
Giardia lamblia Aurora kinase 0.0075 0.0089 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0063 0.0062 0.0066
Schistosoma mansoni hypothetical protein 0.0131 0.0218 0.0204
Echinococcus multilocularis roundabout 2 0.0068 0.0073 0.008
Loa Loa (eye worm) hypothetical protein 0.0234 0.0459 0.0453
Echinococcus granulosus integrin linked protein kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0703 0.1549 0.1544
Schistosoma mansoni centaurin alpha 0.0065 0.0064 0.005
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Echinococcus granulosus G protein coupled receptor kinase 1 0.2622 0.601 0.7183
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Trypanosoma cruzi hypothetical protein 0.0065 0.0064 0.5483
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0043 0.0015 0.0011
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0063 0.0062 0.0047
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0065 0.0064 0.5483
Leishmania major hypothetical protein, conserved 0.0065 0.0064 0.5483
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0065 0.0064 0.0069
Loa Loa (eye worm) TK/EGFR protein kinase 0.0043 0.0015 0.0009
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0065 0.0064 0.5483
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) AGC/AKT protein kinase 0.0082 0.0104 0.0098
Schistosoma mansoni hypothetical protein 0.0299 0.0609 0.0595
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0065 0.0064 0.0069
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0065 0.0064 0.0413
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0104 0.0583
Loa Loa (eye worm) hypothetical protein 0.0299 0.0609 0.0603
Echinococcus granulosus pdz domain containing protein 0.0065 0.0064 0.0069
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.0015 0.0011
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0061 0.0055 0.0059
Echinococcus granulosus semaphorin 5B 0.0299 0.0609 0.0721
Brugia malayi Uncoordinated protein 104 0.0065 0.0064 0.0058
Echinococcus multilocularis kinase suppressor of Ras 1 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Brugia malayi Variant SH3 domain containing protein 0.0065 0.0064 0.0058
Trypanosoma cruzi PH domain containing protein, putative 0.0065 0.0064 0.5483
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0043 0.0015 0.0011
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Echinococcus multilocularis regulator of G protein signaling 3 0.0703 0.1549 0.1846
Entamoeba histolytica protein kinase, putative 0.0082 0.0104 0.0583
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.3635 0.8365 0.8364
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0065 0.0064 0.005
Echinococcus granulosus raf serine:threonine protein kinase 0.0043 0.0015 0.0011
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus granulosus ephrin type A receptor 4 A 0.0043 0.0015 0.0011
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0703 0.1549 1
Trichomonas vaginalis conserved hypothetical protein 0.0703 0.1549 1
Brugia malayi hypothetical protein 0.0703 0.1549 0.1544
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0065 0.0064 0.032
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Leishmania major protein kinase, putative 0.0075 0.0089 0.827
Brugia malayi C-terminal src kinase protein 1 0.0043 0.0015 0.0009
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0107 0.0163 0.0157
Brugia malayi Oxysterol-binding protein 0.0065 0.0064 0.0058
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis actin binding protein anillin 0.0065 0.0064 0.0069
Brugia malayi hypothetical protein 0.0299 0.0609 0.0603
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Raf kinase 0.0043 0.0015 0.0009
Echinococcus granulosus tyrosine protein kinase csk 0.0043 0.0015 0.0011
Echinococcus granulosus transcription factor collier 0.0131 0.0218 0.0254
Echinococcus granulosus serine/threonine protein kinase 0.0082 0.0104 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus regulator of G protein signaling 3 0.0703 0.1549 0.1846
Entamoeba histolytica hypothetical protein 0.0703 0.1549 1
Echinococcus multilocularis dynamin 1 0.0065 0.0064 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Echinococcus granulosus Regulator of G protein signaling 20 0.0703 0.1549 0.1846
Trypanosoma cruzi NIMA-related kinase, putative 0.0082 0.0104 1
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trypanosoma cruzi hypothetical protein 0.0065 0.0064 0.5483
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis exocyst complex component 2 0.0131 0.0218 0.0254
Echinococcus granulosus tyrosine protein kinase Lyn 0.0061 0.0055 0.0059
Echinococcus granulosus cytohesin 1 0.0065 0.0064 0.0069
Entamoeba histolytica protein kinase, putative 0.0082 0.0104 0.0583
Entamoeba histolytica protein kinase, putative 0.0082 0.0104 0.0583
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0703 0.1549 0.1537
Entamoeba histolytica protein kinase domain containing protein 0.0061 0.0055 0.0264
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Tyrosine-protein kinase PR2 0.0043 0.0015 0.0009
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Schistosoma mansoni serine/threonine-protein kinase 0.0082 0.0104 0.009
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0065 0.0064 0.0069
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus granulosus beta-adrenergic receptor kinase 0.3325 0.7645 0.9139
Onchocerca volvulus Putative zinc finger protein 0.0065 0.0064 0.032
Echinococcus granulosus tyrosine kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Brugia malayi Oxysterol binding protein 0.0065 0.0064 0.0058
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0043 0.0015 0.0011
Schistosoma mansoni protein kinase 0.0075 0.0089 0.0075
Loa Loa (eye worm) sema domain-containing protein 0.0299 0.0609 0.0603
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Schistosoma mansoni zinc finger protein 0.0065 0.0064 0.005
Leishmania major hypothetical protein, conserved 0.0065 0.0064 0.5483
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0703 0.1549 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0082 0.0104 1
Loa Loa (eye worm) TK/FAK protein kinase 0.0043 0.0015 0.0009
Entamoeba histolytica PH domain containing protein 0.0065 0.0064 0.032
Leishmania major protein kinase, putative 0.0061 0.0055 0.4517
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0082 0.0104 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Echinococcus granulosus oxysterol binding protein 9 0.0065 0.0064 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0703 0.1549 1
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus multilocularis FL cytokine receptor 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0068 0.0073 0.0067
Echinococcus multilocularis c src tyrosine kinase 0.0043 0.0015 0.0011
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Trichomonas vaginalis alpha chimerin, putative 0.0065 0.0064 0.0413
Entamoeba histolytica hypothetical protein 0.0703 0.1549 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0043 0.0015 0.0011
Trypanosoma cruzi hypothetical protein 0.0065 0.0064 0.5483
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0043 0.0015 0.0009
Entamoeba histolytica protein kinase, putative 0.0075 0.0089 0.0483
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0043 0.0015 0.0011
Schistosoma mansoni hypothetical protein 0.0403 0.0852 0.0839
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Schistosoma mansoni vav2 0.0065 0.0064 0.005
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0107 0.0163 0.0157
Entamoeba histolytica hypothetical protein 0.0065 0.0064 0.032
Schistosoma mansoni regulator of G protein signaling 0.0703 0.1549 0.1537
Echinococcus granulosus tyrosine protein kinase Blk 0.0043 0.0015 0.0011
Loa Loa (eye worm) TK/CSK protein kinase 0.0043 0.0015 0.0009
Brugia malayi Regulator of G protein signaling domain containing protein 0.0703 0.1549 0.1544
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0065 0.0064 0.0413
Brugia malayi serine/threonine protein kinase 6 0.0075 0.0089 0.0083
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus retinal guanylyl cyclase 2 0.0043 0.0015 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0043 0.0015 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Brugia malayi Variant SH3 domain containing protein 0.0065 0.0064 0.0058
Toxoplasma gondii protein kinase domain-containing protein 0.0082 0.0104 1
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0131 0.0218 0.141
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0082 0.0104 1
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus neuroglian 0.0063 0.0062 0.0066
Echinococcus multilocularis epidermal growth factor receptor 0.0043 0.0015 0.0011
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0043 0.0015 0.0011
Echinococcus multilocularis Regulator of G protein signaling 20 0.0703 0.1549 0.1846
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0075 0.0089 0.0483
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0043 0.0015 0.0009
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis centaurin alpha, putative 0.0065 0.0064 0.0413
Brugia malayi hypothetical protein 0.0703 0.1549 0.1544
Loa Loa (eye worm) TK/Met protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Schistosoma mansoni goodpasture antigen-binding protein 0.0065 0.0064 0.005
Echinococcus multilocularis tyrosine kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0068 0.0073 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trypanosoma cruzi NIMA-related kinase, putative 0.0082 0.0104 1
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Loa Loa (eye worm) hypothetical protein 0.0063 0.0062 0.0056
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0065 0.0064 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0065 0.0064 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0089 0.0574
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Echinococcus multilocularis beta adrenergic receptor kinase 0.3325 0.7645 0.9139
Echinococcus multilocularis tyrosine protein kinase Blk 0.0043 0.0015 0.0011
Echinococcus granulosus tyrosine protein kinase HCK 0.0043 0.0015 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0218 0.141
Echinococcus multilocularis oxysterol binding protein 3 0.0065 0.0064 0.0069
Onchocerca volvulus 0.0065 0.0064 0.032
Schistosoma mansoni hypothetical protein 0.0065 0.0064 0.005
Trichomonas vaginalis STE family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Guanylyl cyclase protein 23 0.0043 0.0015 0.0009
Toxoplasma gondii AtPH1 family protein 0.0065 0.0064 0.5483
Echinococcus granulosus tyrosine kinase 0.0043 0.0015 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0043 0.0015 0.0011
Onchocerca volvulus 0.0065 0.0064 0.032
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Plasmodium falciparum oxysterol-binding protein, putative 0.0065 0.0064 0.5483
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis semaphorin 5B 0.0299 0.0609 0.0721
Plasmodium vivax PH domain containing protein 0.0065 0.0064 0.5483
Echinococcus multilocularis heat shock protein 70 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Trichomonas vaginalis centaurin gamma, putative 0.0065 0.0064 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0043 0.0015 0.0011
Schistosoma mansoni growth factor receptor-bound protein 0.0065 0.0064 0.005
Brugia malayi TBC domain containing protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0043 0.0015 0.0011
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0065 0.0064 0.005
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi A-kinase anchor protein 10, precursor 0.0703 0.1549 0.1544
Brugia malayi SH2 domain containing protein 0.0043 0.0015 0.0009
Echinococcus granulosus fibroblast growth factor receptor 4 0.0043 0.0015 0.0011
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0082 0.0104 1
Schistosoma mansoni hypothetical protein 0.0065 0.0064 0.005
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0065 0.0064 0.032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0043 0.0015 0.0011
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0082 0.0104 0.0674
Echinococcus multilocularis tyrosine protein kinase csk 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis calcium dependent secretion activator 1 0.0065 0.0064 0.0069
Echinococcus granulosus oxysterol binding protein 3 0.0065 0.0064 0.0069
Brugia malayi Probable exocyst complex component Sec5 0.0131 0.0218 0.0213
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0015 0.0096
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0043 0.0015 0.0011
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0065 0.0064 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0082 0.0104 0.0674
Onchocerca volvulus 0.0299 0.0609 0.3877
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0065 0.0064 0.032
Brugia malayi Plekhf2 protein 0.0065 0.0064 0.0058
Entamoeba histolytica cell surface protease gp63, putative 0.0131 0.0218 0.1326
Entamoeba histolytica protein kinase, putative 0.0082 0.0104 0.0583
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Echinococcus multilocularis myotubularin protein 13 0.0065 0.0064 0.0069
Echinococcus multilocularis tyrosine protein kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0043 0.0015 0.0009
Entamoeba histolytica p21-activated kinase 0.0082 0.0104 0.0583
Leishmania major folate/biopterin transporter, putative 0.0082 0.0104 1
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0043 0.0015 0.0096
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0065 0.0064 0.032
Echinococcus multilocularis regulator of G protein signaling 3 0.0703 0.1549 0.1846
Schistosoma mansoni hypothetical protein 0.0065 0.0064 0.005
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis natriuretic peptide receptor 1 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Entamoeba histolytica protein kinase, putative 0.0075 0.0089 0.0483
Echinococcus granulosus Pleckstrin y 0.0065 0.0064 0.0069
Entamoeba histolytica protein kinase, putative 0.0082 0.0104 0.0583
Onchocerca volvulus 0.0065 0.0064 0.032
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) oxysterol binding protein 0.0065 0.0064 0.0058
Echinococcus granulosus tyrosine protein kinase Srms 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis Immunoglobulin 0.0063 0.0062 0.0066
Entamoeba histolytica hypothetical protein 0.0065 0.0064 0.032
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0065 0.0064 0.5483
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0089 0.0574
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) RGC/RGC protein kinase 0.0043 0.0015 0.0009
Echinococcus granulosus calcium dependent secretion activator 1 0.0065 0.0064 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Trypanosoma cruzi PH domain containing protein, putative 0.0065 0.0064 0.5483
Brugia malayi serine/threonine-protein kinase 6 0.0075 0.0089 0.0083
Brugia malayi Dynamin 0.0065 0.0064 0.0058
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0065 0.0064 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus granulosus Oxysterol binding protein 11 0.0065 0.0064 0.0069
Brugia malayi hypothetical protein 0.0068 0.0073 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0218 0.141
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0089 0.0574
Echinococcus multilocularis regulator of G protein signaling 0.0703 0.1549 0.1846
Loa Loa (eye worm) TK/EPH protein kinase 0.0043 0.0015 0.0009
Brugia malayi Sema domain containing protein 0.0299 0.0609 0.0603
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0218 0.141
Echinococcus multilocularis expressed protein 0.0703 0.1549 0.1846
Trichomonas vaginalis conserved hypothetical protein 0.0703 0.1549 1
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Schistosoma mansoni hypothetical protein 0.0131 0.0218 0.0204
Echinococcus multilocularis raf serine:threonine protein kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Trichomonas vaginalis centaurin/arf, putative 0.0065 0.0064 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0702 0.1547 0.1542
Echinococcus granulosus regulator of G protein signaling 7 0.0703 0.1549 0.1846
Trypanosoma cruzi hypothetical protein 0.0065 0.0064 0.5483
Onchocerca volvulus 0.0065 0.0064 0.032
Brugia malayi integrin-linked kinase 0.0043 0.0015 0.0009
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0075 0.0089 0.0099
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0089 0.0083
Loa Loa (eye worm) rho-GTPase-activating 0.0065 0.0064 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Echinococcus granulosus kinase suppressor of Ras 1 0.0043 0.0015 0.0011
Loa Loa (eye worm) uncoordinated protein 104 0.0065 0.0064 0.0058
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0065 0.0064 0.032
Loa Loa (eye worm) sema domain-containing protein 0.0299 0.0609 0.0603
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Echinococcus granulosus beta 1 syntrophin 0.0065 0.0064 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0015 0.0096
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0082 0.0104 1
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Onchocerca volvulus 0.0702 0.1547 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.3325 0.7645 0.7644
Schistosoma mansoni axis inhibition protein axin 0.0703 0.1549 0.1537
Loa Loa (eye worm) hypothetical protein 0.0299 0.0609 0.0603
Brugia malayi hypothetical protein 0.0299 0.0609 0.0603
Echinococcus multilocularis epidermal growth factor receptor 0.0043 0.0015 0.0011
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0065 0.0064 0.5483
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Entamoeba histolytica hypothetical protein 0.0131 0.0218 0.1326
Echinococcus multilocularis pdz domain containing protein 0.0065 0.0064 0.0069
Loa Loa (eye worm) hypothetical protein 0.0131 0.0218 0.0213
Loa Loa (eye worm) hypothetical protein 0.0703 0.1549 0.1544
Brugia malayi Syntrophin-1 0.0065 0.0064 0.0058
Trypanosoma brucei rac serine-threonine kinase, putative 0.0082 0.0104 1
Entamoeba histolytica hypothetical protein 0.0065 0.0064 0.032
Brugia malayi ephrin receptor 1 precursor 0.0043 0.0015 0.0009
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0075 0.0089 0.0483
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0065 0.0064 0.0413
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus multilocularis regulator of G protein signaling 7 0.0703 0.1549 0.1846
Brugia malayi hypothetical protein 0.0043 0.0015 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0131 0.0218 0.141
Schistosoma mansoni protein kinase 0.0061 0.0055 0.0041
Entamoeba histolytica protein kinase, putative 0.0082 0.0104 0.0583
Echinococcus granulosus exocyst complex component 2 0.0131 0.0218 0.0254
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Toxoplasma gondii aurora kinase 0.0075 0.0089 0.827
Trypanosoma cruzi Protein kinase B 0.0082 0.0104 1
Loa Loa (eye worm) AUR protein kinase 0.0075 0.0089 0.0083
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Echinococcus granulosus tyrosine protein kinase pr2 0.0043 0.0015 0.0011
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0082 0.0104 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0703 0.1549 0.1537
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Loa Loa (eye worm) PH domain-containing protein 0.0065 0.0064 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Schistosoma mansoni z-protein (S1r protein) 0.0703 0.1549 0.1537
Loa Loa (eye worm) TK/RYK protein kinase 0.0043 0.0015 0.0009
Brugia malayi PXA domain containing protein 0.0703 0.1549 0.1544
Entamoeba histolytica hypothetical protein 0.0082 0.0104 0.0583
Trypanosoma cruzi hypothetical protein 0.0065 0.0064 0.5483
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0075 0.0089 0.0483
Onchocerca volvulus outspread protein homolog 0.0065 0.0064 0.032
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus granulosus tyrosine protein kinase csk 0.0043 0.0015 0.0011
Echinococcus multilocularis transcription factor collier 0.0131 0.0218 0.0254
Trypanosoma brucei PH domain containing protein, putative 0.0065 0.0064 0.5483
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis Immunoglobulin 0.0063 0.0062 0.0066
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) RGC/RGC protein kinase 0.0043 0.0015 0.0009
Echinococcus multilocularis axis inhibition protein axin 0.0703 0.1549 0.1846
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis tyrosine protein kinase csk 0.0043 0.0015 0.0011
Echinococcus granulosus activated cdc42 kinase 1 0.0043 0.0015 0.0011
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0065 0.0064 0.032
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Loa Loa (eye worm) TK/ACK protein kinase 0.0043 0.0015 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.3325 0.7645 0.7642
Echinococcus multilocularis protein tyrosine kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Echinococcus granulosus insulin receptor 0.0043 0.0015 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0703 0.1549 1
Echinococcus multilocularis Oxysterol binding protein 11 0.0065 0.0064 0.0069
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0082 0.0104 1
Toxoplasma gondii Oxysterol-binding protein 0.0065 0.0064 0.5483
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Entamoeba histolytica PH domain containing protein 0.0065 0.0064 0.032
Brugia malayi Plexin repeat family protein 0.0702 0.1547 0.1542
Loa Loa (eye worm) SRC-1 0.0043 0.0015 0.0009
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.3635 0.8365 0.8364
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0043 0.0015 0.0011
Schistosoma mansoni hypothetical protein 0.0065 0.0064 0.005
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Echinococcus granulosus tyrosine kinase 0.0043 0.0015 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0089 0.0574
Onchocerca volvulus Protein melted homolog 0.0065 0.0064 0.032
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0082 0.0104 1
Toxoplasma gondii hypothetical protein 0.0065 0.0064 0.5483
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0703 0.1549 0.1537
Echinococcus multilocularis tyrosine protein kinase HCK 0.0043 0.0015 0.0011
Brugia malayi DNA-binding protein LAG-1 0.0131 0.0218 0.0213
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis protein transport protein sec7, putative 0.0065 0.0064 0.0413
Entamoeba histolytica protein kinase domain containing protein 0.0075 0.0089 0.0483
Trypanosoma cruzi hypothetical protein 0.0065 0.0064 0.5483
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0043 0.0015 0.0011
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0082 0.0104 1
Echinococcus granulosus Rho GTPase activating protein 24 0.0065 0.0064 0.0069
Echinococcus multilocularis cytohesin 1 0.0065 0.0064 0.0069
Schistosoma mansoni regulator of G protein signaling 0.0703 0.1549 0.1537
Echinococcus multilocularis integrin linked protein kinase 0.0043 0.0015 0.0011
Brugia malayi PXA domain containing protein 0.0703 0.1549 0.1544
Schistosoma mansoni hypothetical protein 0.0065 0.0064 0.005
Loa Loa (eye worm) hypothetical protein 0.0299 0.0609 0.0603
Entamoeba histolytica hypothetical protein 0.0131 0.0218 0.1326
Schistosoma mansoni semaphorin 5-related 0.0299 0.0609 0.0595
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0131 0.0218 0.141
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0061 0.0055 0.4517
Brugia malayi SRC-1 0.0043 0.0015 0.0009
Echinococcus multilocularis insulin receptor 0.0043 0.0015 0.0011
Echinococcus granulosus oxysterol binding protein 1 0.0065 0.0064 0.0069
Loa Loa (eye worm) hypothetical protein 0.0703 0.1549 0.1544
Echinococcus multilocularis tyrosine protein kinase csk 0.0043 0.0015 0.0011
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0065 0.0064 0.0069
Echinococcus granulosus protein kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0104 0.0583
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0065 0.0064 0.032
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0061 0.0055 0.0059
Echinococcus granulosus aurora kinase A 0.0075 0.0089 0.0099
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0061 0.0055 0.4517
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0043 0.0015 0.0011
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0043 0.0015 0.0011
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0043 0.0015 0.0011
Echinococcus granulosus Immunoglobulin 0.0063 0.0062 0.0066
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0043 0.0015 0.0011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Plasmodium falciparum protein kinase, putative 0.0061 0.0055 0.4517
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Onchocerca volvulus 0.0065 0.0064 0.032
Trichomonas vaginalis protein transport protein sec7, putative 0.0065 0.0064 0.0413
Echinococcus granulosus natriuretic peptide receptor 1 0.0043 0.0015 0.0011
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Echinococcus granulosus tyrosine protein kinase csk 0.0043 0.0015 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Schistosoma mansoni rho gtpase activating protein 0.0065 0.0064 0.005
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis protein KINase family member (kin 25) 0.0043 0.0015 0.0011
Echinococcus granulosus tyrosine protein kinase ABL1 0.0043 0.0015 0.0011
Loa Loa (eye worm) plexin A 0.0833 0.1851 0.1846
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0063 0.0062 0.0066
Plasmodium falciparum PH domain-containing protein, putative 0.0065 0.0064 0.5483
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Fibronectin type III domain containing protein 0.0068 0.0073 0.0067
Echinococcus granulosus regulator of G protein signaling 3 0.0703 0.1549 0.1846
Entamoeba histolytica hypothetical protein 0.0131 0.0218 0.1326
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0703 0.1549 0.1544
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Brugia malayi MAX-1A 0.0065 0.0064 0.0058
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0043 0.0015 0.0011
Echinococcus multilocularis GRB2 associated binding protein 3 0.0065 0.0064 0.0069
Brugia malayi protein-tyrosine kinase 0.0043 0.0015 0.0009
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0065 0.0064 0.032
Echinococcus multilocularis Pleckstrin y 0.0065 0.0064 0.0069
Echinococcus granulosus GRB2 associated binding protein 3 0.0065 0.0064 0.0069
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0131 0.0218 0.141
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis hypothetical protein 0.0299 0.0609 0.0721
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0043 0.0015 0.0009
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0065 0.0064 0.005
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0065 0.0064 0.5483
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Schistosoma mansoni regulator of G protein signaling 0.0703 0.1549 0.1537
Echinococcus multilocularis G protein coupled receptor kinase 6 0.3635 0.8365 1
Loa Loa (eye worm) cytohesin 3 0.0065 0.0064 0.0058
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0703 0.1549 0.1846
Echinococcus multilocularis ephrin type A receptor 4 A 0.0043 0.0015 0.0011
Schistosoma mansoni nephrin 0.0068 0.0073 0.0059
Trichomonas vaginalis centaurin/arf, putative 0.0065 0.0064 0.0413
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0065 0.0064 0.0069
Echinococcus multilocularis activin receptor type 0.0061 0.0055 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0065 0.0064 0.0069
Echinococcus granulosus plexin a4 0.0833 0.1851 0.2208
Brugia malayi serine/threonine kinase 12 0.0075 0.0089 0.0083
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0082 0.0104 1
Echinococcus granulosus twitchin 0.0081 0.0102 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0043 0.0015 0.0096
Brugia malayi SH2 domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis activated cdc42 kinase 1 0.0043 0.0015 0.0011
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0065 0.0064 0.0058
Brugia malayi hypothetical protein 0.0043 0.0015 0.0009
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0065 0.0064 0.0069
Echinococcus granulosus tyrosine protein kinase shark 0.0043 0.0015 0.0011
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0065 0.0064 0.032
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0043 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0703 0.1549 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0703 0.1549 0.1846
Schistosoma mansoni cell adhesion molecule 0.0068 0.0073 0.0059
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0082 0.0104 1
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Trypanosoma brucei protein kinase, putative 0.0082 0.0104 1
Schistosoma mansoni hypothetical protein 0.0299 0.0609 0.0595
Echinococcus granulosus myotubularin protein 13 0.0065 0.0064 0.0069
Brugia malayi PH domain containing protein 0.0065 0.0064 0.0058
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Echinococcus multilocularis tyrosine protein kinase Srms 0.0043 0.0015 0.0011
Echinococcus multilocularis rac serine:threonine kinase 0.0082 0.0104 0.0118
Plasmodium falciparum serine/threonine protein kinase, putative 0.0075 0.0089 0.827
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0065 0.0064 0.5483
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0104 0.0583
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0065 0.0064 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis plexin a4 0.0833 0.1851 0.2208
Schistosoma mansoni ephrin receptor 0.0048 0.0026 0.0012
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0065 0.0064 0.5483
Loa Loa (eye worm) hypothetical protein 0.0063 0.0062 0.0056
Leishmania major protein kinase, putative 0.0082 0.0104 1
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) protein kinase domain-containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Cytohesin 3 0.0065 0.0064 0.0058
Loa Loa (eye worm) hypothetical protein 0.0063 0.0062 0.0056
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Brugia malayi hypothetical protein 0.0043 0.0015 0.0009
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0043 0.0015 0.0011
Schistosoma mansoni protein kinase 0.0061 0.0055 0.0041
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0065 0.0064 0.5483
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0043 0.0015 0.0009
Entamoeba histolytica ARF GTPase activating protein, putative 0.0065 0.0064 0.032
Brugia malayi regulator of G-protein signaling egl-10 0.0703 0.1549 0.1544
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus granulosus axis inhibition protein axin 0.0703 0.1549 0.1846
Trichomonas vaginalis TK family protein kinase 0.0043 0.0015 0.0096
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0082 0.0104 1
Loa Loa (eye worm) RGS-3 protein 0.0703 0.1549 0.1544
Trichomonas vaginalis protein tyrosine kinase, putative 0.0043 0.0015 0.0096
Echinococcus multilocularis tyrosine protein kinase Abl 0.0043 0.0015 0.0011
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0065 0.0064 0.5483
Brugia malayi regulator of G-protein signaling rgs-7 0.0703 0.1549 0.1544
Brugia malayi IPT/TIG domain containing protein 0.0131 0.0218 0.0213
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0065 0.0064 0.0069
Loa Loa (eye worm) hypothetical protein 0.0703 0.1549 0.1544
Echinococcus multilocularis DCC interacting protein 13 beta 0.0065 0.0064 0.0069
Echinococcus granulosus semaphorin 1A 0.0299 0.0609 0.0721
Echinococcus granulosus regulator of G protein signaling 7 0.0703 0.1549 0.1846
Echinococcus granulosus Pleckstrin y 0.0065 0.0064 0.0069
Onchocerca volvulus 0.0065 0.0064 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Loa Loa (eye worm) TK/DDR protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Echinococcus granulosus activin receptor type 0.0061 0.0055 0.0059
Schistosoma mansoni oxysterol-binding protein 1 0.0065 0.0064 0.005
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0065 0.0064 0.0413
Brugia malayi Receptor family ligand binding region containing protein 0.0043 0.0015 0.0009
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0065 0.0064 0.0413
Trypanosoma cruzi hypothetical protein 0.0065 0.0064 0.5483
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.3635 0.8365 1
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0015 0.0096
Trypanosoma brucei aurora B kinase 0.0075 0.0089 0.827
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0065 0.0064 0.005
Echinococcus multilocularis tyrosine protein kinase shark 0.0043 0.0015 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.3325 0.7645 0.7642
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0218 0.141
Echinococcus granulosus tyrosine protein kinase Src64B 0.0043 0.0015 0.0011
Echinococcus multilocularis tyrosine protein kinase csk 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) serine/threonine protein kinase 0.0043 0.0015 0.0009
Schistosoma mansoni zinc finger protein 0.0065 0.0064 0.005
Schistosoma mansoni fibrocystin l 0.0131 0.0218 0.0204
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0065 0.0064 0.0058
Trichomonas vaginalis kinesin light chain, putative 0.0065 0.0064 0.0413
Entamoeba histolytica hypothetical protein 0.0703 0.1549 1
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Schistosoma mansoni goodpasture antigen-binding protein 0.0065 0.0064 0.005
Trichomonas vaginalis protein kinase atn1, putative 0.0043 0.0015 0.0096
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trypanosoma cruzi PH domain containing protein, putative 0.0065 0.0064 0.5483
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Brugia malayi Regulator of G protein signaling domain containing protein 0.0703 0.1549 0.1544
Echinococcus granulosus dynamin 1 0.0065 0.0064 0.0069
Schistosoma mansoni regulator of G protein signaling 0.0703 0.1549 0.1537
Leishmania major protein kinase, putative 0.0082 0.0104 1
Echinococcus granulosus axis inhibition protein axin 0.0703 0.1549 0.1846
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Brugia malayi probable spectrin beta chain 0.0065 0.0064 0.0058
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0082 0.0104 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0061 0.0055 0.4517
Toxoplasma gondii hypothetical protein 0.0065 0.0064 0.5483
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0015 0.0096
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0063 0.0062 0.0047
Loa Loa (eye worm) Plekhf2 protein 0.0065 0.0064 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0061 0.0055 0.4517
Trichomonas vaginalis CAMK family protein kinase 0.0043 0.0015 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus granulosus defective proboscis extension response 0.0063 0.0062 0.0066
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) hypothetical protein 0.0068 0.0073 0.0067
Brugia malayi Cadps2 protein 0.0065 0.0064 0.0058
Loa Loa (eye worm) hypothetical protein 0.0403 0.0852 0.0846
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.3635 0.8365 0.8364
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.0015 0.0011
Entamoeba histolytica hypothetical protein 0.0065 0.0064 0.032
Loa Loa (eye worm) hypothetical protein 0.0063 0.0062 0.0056
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0075 0.0089 0.0099
Echinococcus multilocularis transfer RNA-Thr 0.0043 0.0015 0.0011
Echinococcus granulosus DCC interacting protein 13 beta 0.0065 0.0064 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0015 0.0096
Schistosoma mansoni dynamin 0.0065 0.0064 0.005
Loa Loa (eye worm) syntrophin-1 0.0065 0.0064 0.0058
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0043 0.0015 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0063 0.0062 0.0056
Brugia malayi plexin A 0.0833 0.1851 0.1846
Echinococcus multilocularis tyrosine protein kinase pr2 0.0043 0.0015 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Loa Loa (eye worm) TK protein kinase 0.0043 0.0015 0.0009
Schistosoma mansoni protein kinase 0.0061 0.0055 0.0041
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0043 0.0015 0.0011
Echinococcus granulosus retinal guanylyl cyclase 2 0.0043 0.0015 0.0011
Echinococcus multilocularis tyrosine kinase 0.0043 0.0015 0.0011
Echinococcus granulosus activated cdc42 kinase 1 0.0043 0.0015 0.0011
Entamoeba histolytica protein kinase , putative 0.0075 0.0089 0.0483
Echinococcus multilocularis aurora kinase A 0.0075 0.0089 0.0099
Loa Loa (eye worm) TK/FER protein kinase 0.0043 0.0015 0.0009
Echinococcus multilocularis Pleckstrin y 0.0065 0.0064 0.0069
Brugia malayi Protein kinase domain containing protein 0.0082 0.0104 0.0098
Entamoeba histolytica protein kinase, putative 0.0082 0.0104 0.0583
Echinococcus granulosus c src tyrosine kinase 0.0043 0.0015 0.0011
Loa Loa (eye worm) TK/ABL protein kinase 0.0043 0.0015 0.0009
Schistosoma mansoni serine/threonine-protein kinase 0.0082 0.0104 0.009
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0082 0.0104 1
Schistosoma mansoni plexin 0.0403 0.0852 0.0839
Echinococcus granulosus retinal guanylyl cyclase 2 0.0043 0.0015 0.0011
Entamoeba histolytica tyrosin kinase, putative 0.0174 0.0319 0.1984
Brugia malayi Protein kinase domain containing protein 0.0043 0.0015 0.0009
Schistosoma mansoni vesicular amine transporter 0.0066 0.0068 0.0053
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0043 0.0015 0.0011
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0026 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0218 0.141
Loa Loa (eye worm) RGC/RGC protein kinase 0.0043 0.0015 0.0009
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0015 0.0011
Echinococcus granulosus epidermal growth factor receptor 0.0043 0.0015 0.0011
Echinococcus granulosus receptor type guanylyl cyclase 0.0043 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0065 0.0064 0.0058
Echinococcus multilocularis Rho GTPase activating protein 24 0.0065 0.0064 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0218 0.141
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis Pleckstrin y 0.0065 0.0064 0.0069
Schistosoma mansoni regulator of G protein signaling 0.0703 0.1549 0.1537
Loa Loa (eye worm) TK/ALK protein kinase 0.031 0.0634 0.0629
Loa Loa (eye worm) PXA domain-containing protein 0.0703 0.1549 0.1544
Echinococcus granulosus protein tyrosine kinase 0.0043 0.0015 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Echinococcus multilocularis G protein coupled receptor kinase 1 0.2622 0.601 0.7183
Trichomonas vaginalis centaurin beta, putative 0.0065 0.0064 0.0413
Schistosoma mansoni plexin 0.0702 0.1547 0.1535
Loa Loa (eye worm) TK/INSR protein kinase 0.0043 0.0015 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0064 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Echinococcus multilocularis pleckstrin y domain containing family A 0.0065 0.0064 0.0069
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0131 0.0218 0.141
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0009
Echinococcus granulosus roundabout 2 0.0068 0.0073 0.008
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0082 0.0104 1
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0065 0.0064 0.0069
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0043 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0299 0.0609 0.0603
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0104 0.0674
Echinococcus granulosus epidermal growth factor receptor 0.0043 0.0015 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0043 0.0015 0.0096
Brugia malayi Protein kinase domain containing protein 0.031 0.0634 0.0629
Loa Loa (eye worm) hypothetical protein 0.0703 0.1549 0.1544
Entamoeba histolytica PH domain containing protein kinase, putative 0.0082 0.0104 0.0583
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0065 0.0064 0.0069
Echinococcus multilocularis oxysterol binding protein 9 0.0065 0.0064 0.0069
Loa Loa (eye worm) hypothetical protein 0.0131 0.0218 0.0213

Activities

Activity type Activity value Assay description Source Reference
IZ (functional) = 25 mm Antibacterial activity against Escherichia coli assessed as zone of inhibition at 100 ug/ml after 24 hrs by disc diffusion method ChEMBL. 21342736
IZ (functional) = 26 mm Antibacterial activity against Escherichia coli assessed as zone of inhibition at 200 ug/ml after 24 hrs by disc diffusion method ChEMBL. 21342736
MIC (functional) = 200 ug ml-1 Antibacterial activity against Escherichia coli after 24 hrs by microdilution method ChEMBL. 21342736

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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