Detailed information for compound 153484

Basic information

Technical information
  • TDR Targets ID: 153484
  • Name: (2R)-2,5-diamino-N-[(2R)-1-oxo-4-phenyl-1-(qu inolin-3-ylamino)butan-2-yl]pentanamide
  • MW: 419.519 | Formula: C24H29N5O2
  • H donors: 4 H acceptors: 3 LogP: 1.96 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCCC[C@H](C(=O)N[C@@H](C(=O)Nc1cnc2c(c1)cccc2)CCc1ccccc1)N
  • InChi: 1S/C24H29N5O2/c25-14-6-10-20(26)23(30)29-22(13-12-17-7-2-1-3-8-17)24(31)28-19-15-18-9-4-5-11-21(18)27-16-19/h1-5,7-9,11,15-16,20,22H,6,10,12-14,25-26H2,(H,28,31)(H,29,30)/t20-,22-/m1/s1
  • InChiKey: KUXYCYLURMIFID-IFMALSPDSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-2,5-diamino-N-[(1R)-3-phenyl-1-(3-quinolylcarbamoyl)propyl]pentanamide
  • (2R)-2,5-diamino-N-[(1R)-1-[oxo-(3-quinolylamino)methyl]-3-phenylpropyl]pentanamide
  • (2R)-2,5-bis(azanyl)-N-[(2R)-1-oxo-4-phenyl-1-(quinolin-3-ylamino)butan-2-yl]pentanamide
  • (2R)-2,5-diamino-N-[(1R)-3-phenyl-1-(3-quinolylcarbamoyl)propyl]valeramide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0036 0.0025
Loa Loa (eye worm) peptidase family M1 containing protein 0.0013 0.003 0.0031
Echinococcus granulosus tachykinin peptides receptor 99D 0.0016 0.006 0.0064
Brugia malayi Protein-tyrosine phosphatase 1 0.0022 0.0126 0.0141
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.003 0.0209 0.0231
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Trypanosoma brucei aldo-keto reductase, putative 0.0099 0.0931 0.2173
Brugia malayi Serotonin receptor 0.0016 0.006 0.0067
Echinococcus multilocularis dnaJ subfamily C 6 0.0064 0.0563 0.0626
Loa Loa (eye worm) hypothetical protein 0.0052 0.0439 0.0488
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0586 0.0654
Brugia malayi Bromodomain containing protein 0.0033 0.0239 0.0267
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0925 0.3659
Loa Loa (eye worm) hypothetical protein 0.0242 0.2419 0.2698
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0557 0.0529
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0022 0.0126 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0126 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0006 0.0007
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0016 0.006 0.0064
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Mycobacterium leprae Possible oxidoreductase 0.0029 0.0196 0.0046
Schistosoma mansoni hypothetical protein 0.0022 0.0121 0.0135
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0024 0.015 0.0164
Echinococcus granulosus tyrosine protein kinase Src64B 0.0018 0.0083 0.009
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0259 0.0287
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Echinococcus multilocularis aminopeptidase N 0.0013 0.003 0.0031
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0006 0.0005
Brugia malayi intermediate filament protein 0.0028 0.019 0.0212
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0016 0.006 0.0064
Schistosoma mansoni hypothetical protein 0.0016 0.006 0.0067
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0087 0.0798 0.0888
Onchocerca volvulus 0.0025 0.0154 0.0615
Brugia malayi hypothetical protein 0.0022 0.0126 0.0141
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.0931 0.1039
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.0931 0.1419
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0925 0.3659
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0407 0.0454
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0557 0.062
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0394 0.044
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0099 0.0931 0.3686
Schistosoma mansoni hypothetical protein 0.0016 0.0068 0.0076
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.019 0.0209
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0006 0.0005
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Entamoeba histolytica aldose reductase, putative 0.0099 0.0931 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0016 0.006 0.0064
Echinococcus granulosus tar DNA binding protein 0.0066 0.0586 0.0652
Mycobacterium ulcerans oxidoreductase 0.0099 0.0931 0.0904
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0022 0.0126 0.0138
Trichomonas vaginalis set domain proteins, putative 0.0248 0.2476 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0126 0.0141
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0038 0.004
Echinococcus granulosus pyruvate kinase 0.0018 0.0083 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.006 0.0064
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0006 0.0005
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0151 0.012
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0221 0.0221
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0925 0.2103
Echinococcus multilocularis high affinity choline transporter 1 0.0364 0.3681 0.4106
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Brugia malayi ecdysteroid receptor 0.0011 0.0006 0.0007
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Echinococcus multilocularis zinc finger protein 0.002 0.0109 0.012
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0259 0.0939
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0417 0.4233 0.4724
Loa Loa (eye worm) hypothetical protein 0.0074 0.0666 0.0741
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.0971 1 1
Echinococcus granulosus growth factor receptor bound protein 2 0.0016 0.006 0.0064
Brugia malayi TATA binding protein associated factor 0.0013 0.003 0.0033
Toxoplasma gondii hypothetical protein 0.0242 0.2419 0.2419
Onchocerca volvulus 0.0248 0.2476 1
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.004 0.0314 0.0348
Onchocerca volvulus 0.0011 0.0006 0.0017
Leishmania major pyruvate kinase 0.0035 0.0259 0.054
Loa Loa (eye worm) aminopeptidase N 0.0013 0.003 0.0031
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0557 0.0622
Schistosoma mansoni biogenic amine receptor 0.0016 0.006 0.0067
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0259 0.0939
Schistosoma mansoni hypothetical protein 0.003 0.0214 0.0238
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0586 0.0652
Echinococcus multilocularis lamin dm0 0.0028 0.019 0.0209
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0022 0.0126 0.1333
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0154 0.1638
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0016 0.006 0.0064
Echinococcus granulosus g-protein coupled receptor 0.0016 0.006 0.0064
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0022 0.0126 0.0226
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Echinococcus multilocularis lamin 0.0028 0.019 0.0209
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0022 0.0126 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Leishmania major tyrosine specific protein phosphatase, putative 0.0022 0.0126 0.0226
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0006 0.0005
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0006 0.0007
Entamoeba histolytica alcohol dehydrogenase, putative 0.0029 0.0196 0.2086
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0022 0.0126 0.0226
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0006 0.0007
Schistosoma mansoni carbonic anhydrase 0.0242 0.2419 0.2699
Echinococcus granulosus bloom syndrome protein 0.0025 0.0158 0.0173
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0871 0.8961 1
Brugia malayi AKH receptor 0.0016 0.006 0.0067
Echinococcus multilocularis 0.0022 0.0126 0.0138
Schistosoma mansoni aminopeptidase A (M01 family) 0.0013 0.003 0.0033
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Onchocerca volvulus 0.0022 0.0126 0.0501
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0259 0.0287
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.0971 1 1
Onchocerca volvulus 0.0016 0.006 0.0233
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0016 0.006 0.0064
Schistosoma mansoni hypothetical protein 0.0064 0.0563 0.0629
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0016 0.006 0.0233
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Onchocerca volvulus 0.004 0.0314 0.1259
Schistosoma mansoni protein tyrosine phosphatase 0.0022 0.0126 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Echinococcus granulosus orexin receptor type 2 0.0016 0.006 0.0064
Schistosoma mansoni hypothetical protein 0.0242 0.2419 0.2699
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0925 0.103
Brugia malayi Variant SH3 domain containing protein 0.0016 0.006 0.0067
Trypanosoma brucei aminopeptidase, putative 0.0013 0.003 0.007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Brugia malayi Protein-tyrosine phosphatase 0.0022 0.0126 0.0141
Schistosoma mansoni coup transcription factor 0.0011 0.0006 0.0007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.006 0.0067
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0259 0.0259
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0925 0.1032
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Onchocerca volvulus 0.0022 0.0126 0.0501
Brugia malayi G-protein coupled receptor 0.0016 0.006 0.0067
Schistosoma mansoni hypothetical protein 0.0087 0.0798 0.089
Plasmodium falciparum carbonic anhydrase 0.0242 0.2419 0.2419
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0006 0.0005
Trypanosoma brucei aldo/keto reductase, putative 0.0029 0.0196 0.0457
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Brugia malayi nuclear receptor NHR-88 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0151 0.0151
Echinococcus granulosus carbonic anhydrase 0.0242 0.2419 0.2698
Schistosoma mansoni hypothetical protein 0.0016 0.0068 0.0076
Trypanosoma brucei carbonic anhydrase-like protein 0.0417 0.4233 0.9877
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0439 0.0488
Echinococcus granulosus allatostatin A receptor 0.0016 0.006 0.0064
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0925 0.103
Schistosoma mansoni hypothetical protein 0.0016 0.0068 0.0076
Brugia malayi Protein-tyrosine phosphatase 0.0022 0.0126 0.0141
Schistosoma mansoni survival motor neuron protein 0.005 0.0421 0.047
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0034
Brugia malayi G-protein coupled receptor 0.0016 0.006 0.0067
Echinococcus multilocularis GPCR, family 2 0.0016 0.0068 0.0073
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0154 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.006 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0925 0.3659
Onchocerca volvulus 0.0016 0.006 0.0233
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0103 0.0115
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus granulosus carbonic anhydrase 0.0242 0.2419 0.2698
Loa Loa (eye worm) hypothetical protein 0.003 0.0214 0.0236
Schistosoma mansoni lamin 0.0028 0.019 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0151 0.0062
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0082 0.0091
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0242 0.2419 0.2699
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0394 0.0438
Schistosoma mansoni amine GPCR 0.0016 0.006 0.0067
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.0126 0.0138
Echinococcus multilocularis allatostatin A receptor 0.0016 0.006 0.0064
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0259 0.0605
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0089 0.0089
Loa Loa (eye worm) oxidoreductase 0.0099 0.0931 0.1037
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0006 0.0007
Echinococcus granulosus tyrosine protein kinase shark 0.001 0.0002 0.000000015197
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Brugia malayi Protein kinase domain containing protein 0.001 0.0002 0.0002
Toxoplasma gondii aldo-keto reductase 0.0029 0.0196 0.0196
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.003 0.0209 0.0233
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0557 0.124
Echinococcus multilocularis NCK adaptor protein 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.0126 0.0138
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0871 0.8961 1
Plasmodium vivax hypothetical protein, conserved 0.003 0.0214 0.0214
Echinococcus granulosus fmrfamide receptor 0.0016 0.006 0.0064
Trichomonas vaginalis pten, drome, putative 0.0022 0.0126 0.0393
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Brugia malayi PHD-finger family protein 0.003 0.0214 0.0238
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0196 0.068
Loa Loa (eye worm) hypothetical protein 0.0019 0.0089 0.0097
Schistosoma mansoni amine GPCR 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0099 0.0931 0.1037
Onchocerca volvulus 0.0099 0.0931 0.3756
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Echinococcus granulosus neuropeptide receptor 0.0016 0.006 0.0064
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0151 0.0121
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0022 0.0126 0.0138
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0016 0.006 0.0233
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0018 0.0083 0.009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0006 0.0005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0089 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0259 0.054
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0158 0.0176
Echinococcus multilocularis pyruvate kinase 0.0035 0.0259 0.0287
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0394 0.0438
Onchocerca volvulus 0.0099 0.0931 0.3756
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Plasmodium vivax SET domain protein, putative 0.0031 0.0221 0.0221
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Brugia malayi Variant SH3 domain containing protein 0.0016 0.006 0.0067
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0154 0.0004
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0417 0.4233 0.9876
Schistosoma mansoni tyrosine kinase 0.001 0.0002 0.0002
Echinococcus granulosus 7TM GPCR rhodopsin 0.0016 0.006 0.0064
Echinococcus multilocularis sodium:myo inositol cotransporter 0.004 0.0314 0.0348
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0022 0.0126 0.0138
Echinococcus multilocularis aldo keto reductase 0.0099 0.0931 0.1037
Brugia malayi hypothetical protein 0.0013 0.003 0.0033
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0154 0.1638
Echinococcus granulosus 7tm_1 domain containing protein 0.0016 0.006 0.0064
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0082 0.0089
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0018 0.0083 0.009
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0054 0.0057
Onchocerca volvulus 0.0028 0.019 0.0759
Loa Loa (eye worm) apoptosis regulator protein 0.0087 0.0798 0.0888
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.0931 0.1039
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0006 0.0005
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0154 0.0004
Onchocerca volvulus 0.0022 0.0126 0.0501
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus granulosus c src tyrosine kinase 0.0018 0.0083 0.009
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0089 0.0018
Brugia malayi Dopamine receptor protein 1 0.0016 0.006 0.0067
Giardia lamblia Pyruvate kinase 0.0035 0.0259 0.2754
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Schistosoma mansoni nck2/grb4 0.0016 0.006 0.0067
Echinococcus granulosus g protein coupled receptor 0.0016 0.006 0.0064
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0126 0.0126
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0259 0.0287
Loa Loa (eye worm) hypothetical protein 0.0052 0.044 0.0489
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0301 0.0334
Trypanosoma brucei polo-like protein kinase 0.0099 0.0925 0.2158
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0029 0.0196 0.0216
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0054 0.006
Echinococcus granulosus aldo keto reductase 0.0099 0.0931 0.1037
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0557 0.0557
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Toxoplasma gondii aldose reductase, putative 0.0099 0.0931 0.0931
Schistosoma mansoni hypothetical protein 0.0016 0.0068 0.0076
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Loa Loa (eye worm) carbonic anhydrase 3 0.0417 0.4233 0.4722
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0006 0.0005
Giardia lamblia Kinase, PLK 0.0099 0.0925 0.993
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.006 0.0067
Brugia malayi hypothetical protein 0.0022 0.0126 0.0141
Onchocerca volvulus 0.0016 0.006 0.0233
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.2162 0.2411
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0158 0.0523
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0022 0.0126 0.0138
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0802 0.0892
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0016 0.006 0.0067
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0158 0.0523
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0439 0.049
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0259 0.023
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0004 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0394 0.044
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0016 0.006 0.0064
Echinococcus multilocularis g protein coupled receptor 0.0016 0.006 0.0064
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0018 0.0083 0.009
Mycobacterium tuberculosis Conserved protein 0.0029 0.0196 0.0195
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.006 0.0064
Echinococcus multilocularis neuropeptide receptor 0.0016 0.006 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.006 0.0064
Echinococcus granulosus peptide allatostatin:somatostatin 0.0016 0.006 0.0064
Schistosoma mansoni kinase 0.005 0.0419 0.0468
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0016 0.006 0.0067
Brugia malayi TAR-binding protein 0.0066 0.0586 0.0654
Schistosoma mansoni carbonic anhydrase-related 0.0242 0.2419 0.2699
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0016 0.006 0.0067
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0242 0.2419 0.2698
Loa Loa (eye worm) hypothetical protein 0.0364 0.3681 0.4106
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0068 0.0073
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0214 0.0236
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0546 0.0607
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0259 0.104
Brugia malayi hypothetical protein 0.0013 0.003 0.0033
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Onchocerca volvulus 0.0099 0.0931 0.3756
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Echinococcus granulosus high affinity choline transporter 1 0.0364 0.3681 0.4106
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0586 0.0654
Brugia malayi Peptidase family M1 containing protein 0.0013 0.003 0.0033
Echinococcus multilocularis aldo keto reductase 0.0099 0.0931 0.1037
Loa Loa (eye worm) hypothetical protein 0.0216 0.214 0.2386
Echinococcus granulosus neuropeptide s receptor 0.0497 0.5069 0.5656
Onchocerca volvulus 0.0016 0.006 0.0233
Brugia malayi SRC-1 0.0018 0.0083 0.0092
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni pyruvate kinase 0.0035 0.0259 0.029
Echinococcus multilocularis somatostatin receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.004
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0557 0.0622
Brugia malayi hypothetical protein 0.0022 0.0126 0.0141
Loa Loa (eye worm) hypothetical protein 0.0013 0.0033 0.0034
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Onchocerca volvulus 0.0022 0.0126 0.0501
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0214 0.0236
Echinococcus granulosus tyrosine protein kinase Fyn 0.0018 0.0083 0.009
Onchocerca volvulus 0.0028 0.019 0.0759
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.006 0.0067
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0022 0.0126 0.0141
Schistosoma mansoni DNA helicase recq1 0.001 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.0031
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.0971 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.006 0.0067
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.019 0.0212
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0126 0.0141
Brugia malayi steroid hormone receptor 0.0011 0.0006 0.0007
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0004 0.0005
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.006 0.0067
Echinococcus granulosus zinc finger protein 0.002 0.0109 0.012
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0417 0.4233 0.9876
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0394 0.0438
Schistosoma mansoni hypothetical protein 0.0016 0.006 0.0067
Onchocerca volvulus 0.0016 0.006 0.0233
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0087 0.0798 0.0888
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0006 0.0017
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0022 0.0126 0.0141
Schistosoma mansoni DNA helicase recq5 0.001 0.0004 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0552 0.0613
Brugia malayi Sodium:solute symporter family protein 0.004 0.0314 0.035
Onchocerca volvulus 0.0011 0.0014 0.0048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Trichomonas vaginalis aldo/keto reductase, putative 0.0099 0.0931 0.3686
Echinococcus multilocularis c src tyrosine kinase 0.0018 0.0083 0.009
Entamoeba histolytica hypothetical protein 0.0024 0.0151 0.16
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0013 0.003 0.003
Schistosoma mansoni neuropeptide f receptor 76f 0.0016 0.006 0.0067
Echinococcus granulosus tyrosine protein kinase Src42A 0.0018 0.0083 0.009
Echinococcus granulosus voltage gated potassium channel subunit 0.0029 0.0196 0.0216
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0006 0.0007
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.004 0.0314 0.0314
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0196 0.068
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.006 0.0064
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0038 0.004
Echinococcus multilocularis solute carrier family 5 0.004 0.0314 0.0348
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0022 0.0126 0.0138
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.0126 0.0138
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Entamoeba histolytica aminopeptidase, putative 0.0013 0.003 0.0297
Brugia malayi Tachykinin-like peptides receptor 99D 0.0016 0.006 0.0067
Brugia malayi Dopamine receptor 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Echinococcus multilocularis fmrfamide receptor 0.0016 0.006 0.0064
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0022 0.0126 0.0138
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0068 0.0073
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0029 0.0196 0.0784
Brugia malayi Protein kinase domain containing protein 0.001 0.0002 0.0002
Schistosoma mansoni carbonic anhydrase-related 0.0242 0.2419 0.2699
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Onchocerca volvulus 0.0022 0.0126 0.0501
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0006 0.0005
Onchocerca volvulus 0.0022 0.0126 0.0501
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0022 0.0126 0.0138
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0154 0.0172
Trypanosoma cruzi aldo-keto reductase 0.0099 0.0931 0.2118
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0099 0.0931 0.2118
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus multilocularis tyrosine protein kinase shark 0.001 0.0002 0.000000015197
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Echinococcus granulosus microtubule associated protein 2 0.0722 0.741 0.8269
Echinococcus granulosus dnaJ subfamily C 6 0.0064 0.0563 0.0626
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0013 0.003 0.0033
Schistosoma mansoni neuropeptide receptor 0.0016 0.006 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0006 0.0007
Onchocerca volvulus 0.0016 0.006 0.0233
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0154 0.0126
Onchocerca volvulus 0.0016 0.006 0.0233
Brugia malayi hypothetical protein 0.0022 0.0126 0.0141
Onchocerca volvulus 0.0022 0.0126 0.0501
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.0971 1 1
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0083 0.0083
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0407 0.0452
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0006 0.0005
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0035 0.0259 0.0287
Onchocerca volvulus 0.0022 0.0126 0.0501
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Entamoeba histolytica aldose reductase, putative 0.0099 0.0931 1
Echinococcus multilocularis sex peptide receptor 0.0016 0.006 0.0064
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0016 0.006 0.0233
Echinococcus granulosus neuropeptide FF receptor 2 0.0016 0.006 0.0064
Brugia malayi Protein kinase domain containing protein 0.001 0.0002 0.0002
Echinococcus multilocularis g-protein coupled receptor 0.0016 0.006 0.0064
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0006 0.0005
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0022 0.0126 0.0141
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0142 0.0158
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.006 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0405 0.1536
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0016 0.006 0.0064
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.006 0.0064
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0028 0.0185 0.0203
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0016 0.006 0.0064
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0006 0.0005
Leishmania major carbonic anhydrase-like protein 0.0417 0.4233 0.9876
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0242 0.2419 0.2698
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0006 0.0005
Brugia malayi Sex muscle abnormal protein 5 0.0016 0.006 0.0067
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.0595 0.6089 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni myosin xvIII 0.0016 0.006 0.0067
Brugia malayi RNA binding protein 0.0066 0.0586 0.0654
Schistosoma mansoni tyrosine kinase 0.0018 0.0083 0.0092
Echinococcus multilocularis neuropeptide FF receptor 2 0.0016 0.006 0.0064
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0036 0.0363
Leishmania major prostaglandin f synthase, putative 0.0099 0.0931 0.2118
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0006 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0154 0.0293
Brugia malayi putative neuropeptide receptor 0.0016 0.006 0.0067
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Brugia malayi protein-tyrosine kinase 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0087 0.0802 0.0892
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0022 0.0126 0.0138
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Onchocerca volvulus 0.0022 0.0126 0.0501
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.2471 0.2756
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.006 0.0067
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0022 0.0126 0.0501
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0004 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Loa Loa (eye worm) protein-tyrosine phosphatase 0.003 0.0209 0.0231
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0242 0.2419 0.2699
Echinococcus granulosus pyruvate kinase 0.0018 0.0083 0.009
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0154 0.0293
Echinococcus granulosus alpha 1A adrenergic receptor 0.0016 0.006 0.0064
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0016 0.006 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Echinococcus granulosus carbonic anhydrase II 0.0417 0.4233 0.4722
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.0971 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0151 0.0352
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.0971 1 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0016 0.006 0.0064
Brugia malayi Protein kinase domain containing protein 0.001 0.0002 0.0002
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.002 0.0019
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.006 0.0064
Echinococcus granulosus protein tyrosine phosphatase n9 0.0022 0.0126 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0154 0.0125
Plasmodium falciparum phd finger protein, putative 0.003 0.0214 0.0214
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.003 0.0209 0.0231
Echinococcus granulosus tyrosine protein kinase Fyn 0.0018 0.0083 0.009
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Echinococcus multilocularis growth factor receptor bound protein 2 0.0016 0.006 0.0064
Leishmania major C-8 sterol isomerase-like protein 0.0422 0.4286 1
Echinococcus granulosus sodium:myo inositol cotransporter 0.004 0.0314 0.0348
Echinococcus granulosus carbonic anhydrase 0.0242 0.2419 0.2698
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0099 0.0931 0.0792
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0242 0.2419 0.2699
Schistosoma mansoni adapter molecule crk 0.0016 0.006 0.0067
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0013 0.003 0.0033
Schistosoma mansoni microtubule-associated protein tau 0.0722 0.741 0.827
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Brugia malayi Tyrosine-protein kinase abl-1 0.0018 0.0083 0.0092
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0004 0.0002
Trypanosoma brucei Aminopeptidase M1, putative 0.0013 0.003 0.007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0154 0.0125
Brugia malayi jmjC domain containing protein 0.01 0.0936 0.1044
Onchocerca volvulus 0.0016 0.006 0.0233
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0073 0.0073
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.006 0.0064
Brugia malayi putative neuropeptide receptor NPR1 0.0016 0.006 0.0067
Schistosoma mansoni tyrosine kinase 0.0018 0.0083 0.0092
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0557 0.062
Echinococcus granulosus lamin 0.0028 0.019 0.0209
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0022 0.0126 0.0138
Echinococcus multilocularis pyruvate kinase 0.0028 0.0183 0.0202
Echinococcus granulosus serotonin receptor 0.0016 0.006 0.0064
Entamoeba histolytica alcohol dehydrogenase, putative 0.0029 0.0196 0.2086
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.006 0.0064
Echinococcus granulosus somatostatin receptor 0.0016 0.006 0.0064
Echinococcus granulosus pyruvate kinase 0.0035 0.0259 0.0287
Schistosoma mansoni carbonic anhydrase-related 0.0242 0.2419 0.2699
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0242 0.2419 0.2699
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0925 0.3659
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0006 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.002 0.0019
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Schistosoma mansoni neuropeptide receptor 0.0016 0.006 0.0067
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0099 0.0931 0.2118
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Trypanosoma brucei prostaglandin f synthase 0.0099 0.0931 0.2173
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0325 0.3282 0.3282
Chlamydia trachomatis pyruvate kinase 0.0035 0.0259 0.0172
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0925 0.993
Leishmania major pyruvate kinase 0.0035 0.0259 0.054
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.0936 0.1042
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0004 0.0002
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0871 0.8961 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0068 0.0073
Schistosoma mansoni hypothetical protein 0.0016 0.0063 0.007
Echinococcus multilocularis hypothetical protein 0.0022 0.0126 0.0138
Loa Loa (eye worm) hypothetical protein 0.001 0.0004 0.0002
Schistosoma mansoni amine GPCR 0.0016 0.006 0.0067
Brugia malayi ORL1-like opioid receptor 0.0016 0.006 0.0067
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0016 0.006 0.0067
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0259 0.0605
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0013 0.003 0.007
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.006 0.0064
Loa Loa (eye worm) DnaJ domain-containing protein 0.0064 0.0563 0.0626
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0089 0.0097
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0267 0.0298
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0013 0.003 0.0031
Onchocerca volvulus 0.0099 0.0931 0.3756
Loa Loa (eye worm) protein tyrosine phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) oxidoreductase 0.0099 0.0931 0.1037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0154 0.0125
Schistosoma mansoni hypothetical protein 0.0087 0.0798 0.089
Trypanosoma brucei C-8 sterol isomerase, putative 0.0422 0.4286 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0006 0.0005
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0018 0.0083 0.009
Onchocerca volvulus 0.0022 0.0126 0.0501
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0439 0.049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0006 0.0005
Brugia malayi hypothetical protein 0.0022 0.0126 0.0141
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Brugia malayi nuclear hormone receptor 0.0011 0.0006 0.0007
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni alpha-1 adrenergic receptor 0.0016 0.006 0.0067
Echinococcus multilocularis musashi 0.0028 0.019 0.0209
Brugia malayi Dopamine receptor protein 2 0.0016 0.006 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0006 0.0007
Echinococcus multilocularis dro:myosuppressin receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Echinococcus granulosus g protein coupled receptor 0.0016 0.006 0.0064
Brugia malayi PHD-finger family protein 0.0026 0.0167 0.0187
Trypanosoma cruzi aldo/keto reductase, putative 0.0029 0.0196 0.0391
Echinococcus multilocularis neuropeptide receptor A26 0.0497 0.5069 0.5656
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0016 0.006 0.0233
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0087 0.0798 0.089
Onchocerca volvulus 0.0099 0.0931 0.3756
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0011 0.0006 0.0007
Schistosoma mansoni tyrosine kinase 0.0018 0.0083 0.0092
Echinococcus multilocularis pyruvate kinase 0.0018 0.0083 0.009
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0029 0.0196 0.068
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0006 0.0007
Schistosoma mansoni tyrosine kinase 0.0018 0.0083 0.0092
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0016 0.006 0.0067
Onchocerca volvulus 0.0087 0.0802 0.3232
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0022 0.0126 0.0138
Brugia malayi RE15519p 0.0016 0.006 0.0067
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0083 0.0083
Schistosoma mansoni protein tyrosine phosphatase 0.0022 0.0126 0.0141
Schistosoma mansoni pol-related 0.0099 0.0931 0.1039
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.0031
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0586 0.0654
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Onchocerca volvulus 0.0022 0.0126 0.0501
Schistosoma mansoni hypothetical protein 0.0087 0.0798 0.089
Schistosoma mansoni intermediate filament proteins 0.0028 0.019 0.0212
Giardia lamblia Protein tyrosine phosphatase 0.0022 0.0126 0.1315
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Echinococcus multilocularis fmrfamide receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.006 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0006 0.0005
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0016 0.006 0.0064
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0006 0.0005
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.028 0.0311
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0394 0.0438
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0083 0.0083
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.0348
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni opsin-like receptor 0.0016 0.006 0.0067
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.006 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0006 0.0007
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0802 0.0892
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0089 0.0089
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0013 0.003 0.0031
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0214 0.0214
Schistosoma mansoni pcd6 interacting protein-related 0.0022 0.0126 0.0141
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Schistosoma mansoni sodium/solute symporter 0.004 0.0314 0.035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Onchocerca volvulus 0.0022 0.0126 0.0501
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0417 0.4233 0.4722
Loa Loa (eye worm) hypothetical protein 0.0043 0.034 0.0377
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0006 0.0007
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0925 0.2103
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.0931 0.1039
Trypanosoma brucei Aminopeptidase M1, putative 0.0013 0.003 0.007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0022 0.0126 0.0141
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0259 0.104
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.015 0.0164
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Trypanosoma cruzi ISWI complex protein 0.0016 0.0063 0.0078
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0004 0.0002
Brugia malayi Bromodomain containing protein 0.0078 0.0713 0.0796
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0925 0.1032
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0259 0.0301
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0016 0.006 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0099 0.0931 0.3686
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0012 0.0013
Schistosoma mansoni growth hormone secretagogue receptor 0.0016 0.006 0.0067
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0022 0.0126 0.0141
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0022 0.0126 0.0501
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.004 0.0314 0.0348
Echinococcus multilocularis neuropeptide receptor 0.0016 0.006 0.0064
Echinococcus granulosus tyrosine protein kinase Lyn 0.0018 0.0086 0.0094
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0214 0.0214
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0154 0.0126
Trypanosoma cruzi aldo/keto reductase, putative 0.0099 0.0931 0.2118
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0087 0.0798 0.0888
Schistosoma mansoni apoptosis regulator bax 0.0087 0.0798 0.089
Loa Loa (eye worm) melatonin receptor type 1A 0.0016 0.006 0.0064
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0082 0.0089
Echinococcus granulosus aminopeptidase N 0.0013 0.003 0.0031
Loa Loa (eye worm) SRC-1 0.0018 0.0083 0.009
Onchocerca volvulus 4.1 G protein, putative homolog 0.0022 0.0126 0.0501
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0013 0.003 0.0031
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0242 0.2419 0.2698
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0018 0.0083 0.009
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0018 0.0083 0.009
Trypanosoma brucei ISWI complex protein 0.0016 0.0063 0.0147
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0099 0.0931 0.3686
Onchocerca volvulus Neuropeptide F receptor homolog 0.0016 0.006 0.0233
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) hypothetical protein 0.0025 0.0154 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0925 0.3659
Onchocerca volvulus 0.0022 0.0126 0.0501
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0242 0.2419 0.2699
Echinococcus multilocularis pyruvate kinase 0.0018 0.0083 0.009
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0006 0.0007
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Brugia malayi hypothetical protein 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0016 0.006 0.0067
Echinococcus multilocularis orexin receptor type 2 0.0016 0.006 0.0064
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0338 0.0375
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.0031
Echinococcus granulosus G protein coupled receptor 139 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0126 0.1212 0.135
Loa Loa (eye worm) hypothetical protein 0.0019 0.0089 0.0097
Echinococcus granulosus neuropeptide receptor 0.0016 0.006 0.0064
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0022 0.0126 0.0138
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0016 0.006 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0394 0.044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Brugia malayi SH2 domain containing protein 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0361 0.04
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0586 0.0654
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0082 0.0091
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.006 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0925 0.3659
Echinococcus multilocularis G-protein coupled receptor, putative 0.0016 0.006 0.0064
Toxoplasma gondii aminopeptidase N, putative 0.0325 0.3282 0.3282
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.015 0.1586
Brugia malayi larval opioid receptor 0.0016 0.006 0.0067
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.006 0.0067
Schistosoma mansoni inositol transporter 0.004 0.0314 0.035
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.006 0.0064
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) RecQ helicase 0.0025 0.0158 0.0173
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0022 0.0126 0.0141
Schistosoma mansoni hypothetical protein 0.0036 0.0267 0.0298
Leishmania major hypothetical protein, conserved 0.0016 0.0063 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0006 0.0007
Loa Loa (eye worm) TATA binding protein associated factor 0.0013 0.003 0.0031
Brugia malayi neuropeptide F receptor 0.0016 0.006 0.0067
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Brugia malayi Pre-SET motif family protein 0.0031 0.0221 0.0247
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0154 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.019 0.0209
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0016 0.006 0.0067
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0259 0.029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Schistosoma mansoni opsin-like receptor 0.0016 0.006 0.0067
Brugia malayi Peptidase family M1 containing protein 0.0013 0.003 0.0033
Schistosoma mansoni high-affinity choline transporter 0.0364 0.3681 0.4108
Schistosoma mansoni amine GPCR 0.0016 0.006 0.0067
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0259 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0006 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0405 0.1536
Onchocerca volvulus 0.0031 0.0221 0.0886
Echinococcus granulosus g protein coupled receptor 0.0016 0.006 0.0064
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0126 0.0138
Echinococcus multilocularis aldehyde reductase 0.0071 0.0632 0.0702
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.006 0.0064
Echinococcus granulosus aldehyde reductase 0.0071 0.0632 0.0702
Onchocerca volvulus 0.0022 0.0126 0.0501
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.006 0.0064
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0016 0.006 0.0233
Echinococcus multilocularis neuropeptide s receptor 0.0497 0.5069 0.5656
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0004 0.0004
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Schistosoma mansoni hypothetical protein 0.005 0.0421 0.047
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0006 0.0017
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0006 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.006 0.0064
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0546 0.0607
Mycobacterium leprae Conserved hypothetical protein 0.0071 0.0632 0.0488
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0016 0.006 0.0064
Echinococcus multilocularis g protein coupled receptor 0.0016 0.006 0.0064
Echinococcus granulosus aldo keto reductase 0.0099 0.0931 0.1037
Loa Loa (eye worm) intermediate filament protein 0.0028 0.019 0.0209
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Echinococcus multilocularis peregrin 0.0033 0.0239 0.0265
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0121 0.0133
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0006 0.0007
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0087 0.0798 0.0888
Brugia malayi G protein-coupled receptor F59B2.13 0.0016 0.006 0.0067
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Schistosoma mansoni opsin-like receptor 0.0016 0.006 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0417 0.4233 0.4724
Echinococcus multilocularis serotonin receptor 0.0016 0.006 0.0064
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0018 0.0083 0.009
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0016 0.006 0.0067
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0154 0.0125
Loa Loa (eye worm) oxidoreductase 0.0099 0.0931 0.1037
Onchocerca volvulus 0.0022 0.0126 0.0501
Brugia malayi Melatonin receptor type 1A 0.0016 0.006 0.0067
Echinococcus granulosus peregrin 0.0033 0.0239 0.0265
Giardia lamblia Aldose reductase 0.0099 0.0931 1
Echinococcus granulosus hypothetical protein 0.0016 0.006 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0006 0.0007
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.006 0.0064
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.0931 0.1039
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0006 0.0005
Loa Loa (eye worm) TYRA-2 protein 0.0016 0.006 0.0064
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Giardia lamblia PHD finger protein 15 0.003 0.0214 0.226
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0196 0.068
Mycobacterium ulcerans hypothetical protein 0.0029 0.0196 0.0167
Schistosoma mansoni zinc finger protein 0.002 0.0109 0.0122
Echinococcus multilocularis voltage gated potassium channel subunit 0.0029 0.0196 0.0216
Loa Loa (eye worm) hypothetical protein 0.0247 0.2471 0.2756
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0021
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0301 0.0336
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0557 0.0529
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0036 0.0267 0.0296
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0006 0.0007
Echinococcus granulosus intermediate filament protein 0.0028 0.019 0.0209
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0016 0.006 0.0067
Echinococcus multilocularis carbonic anhydrase II 0.0417 0.4233 0.4722
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.2471 0.2756
Schistosoma mansoni lamin 0.0028 0.019 0.0212
Loa Loa (eye worm) hypothetical protein 0.0019 0.0089 0.0097
Brugia malayi Bromodomain containing protein 0.004 0.0313 0.035
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0018 0.0083 0.009
Brugia malayi SH2 domain containing protein 0.001 0.0002 0.0002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0018 0.0083 0.009
Echinococcus granulosus lamin dm0 0.0028 0.019 0.0209
Brugia malayi Protein-tyrosine phosphatase containing protein 0.003 0.0209 0.0233
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0158 0.0173
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0421 0.047
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0802 0.0894
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0016 0.006 0.0064
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0151 0.0121
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Echinococcus multilocularis serotonin receptor 0.0016 0.006 0.0064
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0154 0.0293
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0287 0.0318
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0126 0.0141
Schistosoma mansoni neuropeptide receptor 0.0016 0.006 0.0067
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0018 0.0083 0.009
Onchocerca volvulus 0.0016 0.006 0.0233
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0259 0.054
Loa Loa (eye worm) oxidoreductase 0.0099 0.0931 0.1037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0022 0.0126 0.0138
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0925 0.373
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0004 0.0004
Trypanosoma brucei protein tyrosine phosphatase 1 0.0022 0.0126 0.0294
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0029 0.0196 0.0216
Echinococcus granulosus hypothetical protein 0.0099 0.0931 0.1037
Brugia malayi GH02984p 0.0364 0.3681 0.4108
Echinococcus multilocularis sodium:glucose cotransporter 2 0.004 0.0314 0.0348
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0006 0.0007
Schistosoma mansoni neuropeptide receptor 0.0016 0.006 0.0067
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0557 0.0529
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0301 0.0336
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0018 0.0083 0.009
Entamoeba histolytica aldose reductase, putative 0.0099 0.0931 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0871 0.8961 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0005
Leishmania major aldo-keto reductase-like protein 0.0099 0.0931 0.2118
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0925 0.2103
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0006 0.0007
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0142 0.0156
Schistosoma mansoni zinc finger protein 0.0016 0.0063 0.007
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0029 0.0196 0.0196
Brugia malayi GnHR receptor homolog 0.0016 0.006 0.0067
Schistosoma mansoni potassium channel beta 0.0029 0.0196 0.0219
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0036 0.0014
Trichomonas vaginalis aldo/keto reductase, putative 0.0099 0.0931 0.3686
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0422 0.4286 0.4783
Schistosoma mansoni adenoreceptor 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Onchocerca volvulus 0.0016 0.006 0.0233
Echinococcus granulosus sodium:glucose cotransporter 0.004 0.0314 0.0348
Onchocerca volvulus 0.005 0.0421 0.1695
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Echinococcus granulosus NCK adaptor protein 0.0016 0.006 0.0064
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0325 0.3282 0.3282
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0016 0.006 0.0064
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0087 0.0798 0.089
Brugia malayi Pre-SET motif family protein 0.0218 0.2162 0.2413
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0036 0.0084
Echinococcus granulosus pyruvate kinase 0.0035 0.0259 0.0287
Loa Loa (eye worm) hypothetical protein 0.0019 0.0089 0.0097
Brugia malayi follicle stimulating hormone receptor 0.0016 0.006 0.0067
Schistosoma mansoni histamine h1 receptor 0.0016 0.006 0.0067
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0586 0.0652
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0013 0.003 0.0033
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0871 0.8961 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.006 0.0064
Echinococcus multilocularis g protein coupled receptor 0.0016 0.006 0.0064
Brugia malayi hypothetical protein 0.0016 0.006 0.0067
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Schistosoma mansoni bromodomain containing protein 0.0066 0.0585 0.0653
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0221 0.0247
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0209 0.0231
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0004 0.0002
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0068 0.0076
Echinococcus granulosus sodium:glucose cotransporter 2 0.004 0.0314 0.0348
Plasmodium vivax aldehyde reductase, putative 0.0029 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0006 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0068 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0068 0.0073
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0722 0.0806
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Echinococcus multilocularis G protein coupled receptor 139 0.0016 0.006 0.0064
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.006 0.0064
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0586 0.0652
Schistosoma mansoni protein tyrosine phosphatase 0.0022 0.0126 0.0141
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0022 0.0126 0.0138
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0018 0.0083 0.009
Echinococcus granulosus sex peptide receptor 0.0016 0.006 0.0064
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0016 0.006 0.0064
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.006 0.0067
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.006 0.0064
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0196 0.068
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0071 0.0071
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0029 0.0196 0.0219
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0586 0.0654
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Echinococcus multilocularis pyruvate kinase 0.0035 0.0259 0.0287
Toxoplasma gondii aminopeptidase N protein 0.0325 0.3282 0.3282
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0417 0.4233 0.4724
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Giardia lamblia Aldose reductase 0.0099 0.0931 1
Onchocerca volvulus 0.0013 0.003 0.0112
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0287 0.0318
Giardia lamblia Pyruvate kinase 0.0018 0.0083 0.0847
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0154 0.0172
Onchocerca volvulus 0.0099 0.0931 0.3756
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.003 0.0209 0.0231
Loa Loa (eye worm) RNA binding protein 0.0066 0.0586 0.0652
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.006 0.0064
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0018 0.0083 0.0092
Echinococcus granulosus pyruvate kinase 0.0018 0.0083 0.009
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0154 0.0172
Echinococcus multilocularis carbonic anhydrase 0.0242 0.2419 0.2698
Plasmodium falciparum aldo-keto reductase, putative 0.0029 0.0196 0.0196
Brugia malayi hypothetical protein 0.0247 0.2471 0.2758
Schistosoma mansoni inositol transporter 0.004 0.0314 0.035
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0006 0.0005
Brugia malayi jmjC domain containing protein 0.0039 0.0301 0.0336
Plasmodium falciparum aldehyde reductase, putative 0.0029 0.0196 0.0196
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0221 0.0247
Schistosoma mansoni aldo-keto reductase 0.0099 0.0931 0.1039
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0126 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0006 0.0005
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0016 0.006 0.0067
Echinococcus multilocularis microtubule associated protein 2 0.0722 0.741 0.8269
Toxoplasma gondii aminopeptidase n, putative 0.0325 0.3282 0.3282
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.0931 0.1037
Echinococcus granulosus neuropeptide receptor A26 0.0497 0.5069 0.5656
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0004 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0394 0.0438
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0126 0.0141
Onchocerca volvulus 0.0022 0.0126 0.0501
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Onchocerca volvulus 0.0022 0.0126 0.0501
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.0126 0.0138
Echinococcus granulosus solute carrier family 5 0.004 0.0314 0.0348
Onchocerca volvulus 0.0022 0.0126 0.0501
Loa Loa (eye worm) hypothetical protein 0.004 0.0314 0.0348
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0018 0.0083 0.009
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0022 0.0126 0.1333
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0022 0.0126 0.0141
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0068 0.0076
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.006 0.0067
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0586 0.0654
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0029 0.0196 0.0196
Echinococcus multilocularis aldo keto reductase 0.0099 0.0931 0.1037
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0142 0.0156
Schistosoma mansoni hypothetical protein 0.0016 0.006 0.0067
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Brugia malayi DnaJ domain containing protein 0.0064 0.0563 0.0629
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.006 0.0064
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0006 0.0005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0259 0.104
Loa Loa (eye worm) hypothetical protein 0.0025 0.0154 0.017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0006 0.0005
Trypanosoma cruzi ISWI complex protein 0.0016 0.0063 0.0078
Schistosoma mansoni amine GPCR 0.0016 0.006 0.0067
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0029 0.0196 0.0391
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Schistosoma mansoni biogenic amine receptor 0.0016 0.006 0.0067
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0417 0.4233 0.4724
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0407 0.0452
Onchocerca volvulus 0.0013 0.003 0.0112
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0022 0.0126 0.0138
Schistosoma mansoni hypothetical protein 0.0016 0.006 0.0067
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0154 0.1638
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0259 0.011
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0016 0.006 0.0064
Schistosoma mansoni pyruvate kinase 0.0018 0.0083 0.0092
Loa Loa (eye worm) hypothetical protein 0.0025 0.0154 0.017
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Onchocerca volvulus 0.0016 0.006 0.0233
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0557 0.0797
Echinococcus granulosus GPCR family 2 0.0016 0.0068 0.0073
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0006 0.0005
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0013 0.003 0.0033
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.0931 0.3686
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0013 0.003 0.003
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0259 0.029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0006 0.0007
Onchocerca volvulus 0.0022 0.0126 0.0501
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Loa Loa (eye worm) hypothetical protein 0.0422 0.4286 0.4781
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0925 0.103
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0151 0.0151
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0006 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0301 0.0334
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0214 0.0236
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0029 0.0196 0.0196
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0126 0.0141
Trichomonas vaginalis aldo/keto reductase, putative 0.0099 0.0931 0.3686
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.006 0.0064
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0022 0.0126 0.0138
Brugia malayi Protein kinase domain containing protein 0.001 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.006 0.0067
Echinococcus multilocularis pyruvate kinase 0.0018 0.0083 0.009
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Brugia malayi neuropeptide F receptor 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0049 0.0407 0.0452
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0064
Schistosoma mansoni tyrosine kinase 0.001 0.0002 0.0002
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.0971 1 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0126 0.0141
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0022 0.0126 0.0141
Mycobacterium ulcerans hypothetical protein 0.0025 0.0154 0.0125
Brugia malayi NADH-dependent xylose reductase 0.0029 0.0196 0.0219
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0018 0.0083 0.009
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.003 0.0209 0.0231
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0022 0.0126 0.0141
Echinococcus multilocularis aldo keto reductase 0.0099 0.0931 0.1037
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0126 0.0138
Onchocerca volvulus 0.0016 0.006 0.0233
Loa Loa (eye worm) oxidoreductase 0.0099 0.0931 0.1037
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0022 0.0126 0.0141
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Onchocerca volvulus 0.0013 0.003 0.0112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0126 0.0138
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0151 0.0284
Plasmodium falciparum pyruvate kinase 0.0035 0.0259 0.0259
Echinococcus granulosus aldo keto reductase 0.0099 0.0931 0.1037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0068 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0407 0.0454
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0154 0.0125
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0089 0.0096
Brugia malayi Serotonin receptor 0.0016 0.006 0.0067
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0087 0.0798 0.0888
Onchocerca volvulus Alhambra homolog 0.003 0.0214 0.0855
Echinococcus multilocularis carbonic anhydrase 0.0242 0.2419 0.2698
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.006 0.0064
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0422 0.4286 1
Echinococcus granulosus dro:myosuppressin receptor 0.0016 0.006 0.0064
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0221 0.0245
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0338 0.0375
Echinococcus multilocularis carbonic anhydrase 0.0242 0.2419 0.2698
Schistosoma mansoni biogenic amine receptor 0.0016 0.006 0.0067
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0214 0.0238
Brugia malayi sulfakinin receptor protein 0.0016 0.006 0.0067
Brugia malayi PHD-finger family protein 0.0012 0.0021 0.0023
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.0931 0.1037
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.0936 0.1042
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0013 0.003 0.0031
Schistosoma mansoni aldo-keto reductase 0.0099 0.0931 0.1039
Onchocerca volvulus 0.0022 0.0126 0.0501
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0394 0.044
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0022 0.0126 0.1333
Onchocerca volvulus 0.0016 0.006 0.0233
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0925 0.3659
Onchocerca volvulus 0.0022 0.0126 0.0501
Schistosoma mansoni pyruvate kinase 0.0035 0.0259 0.029
Brugia malayi Peptidase family M1 containing protein 0.0013 0.003 0.0033
Echinococcus multilocularis tyrosine protein kinase Abl 0.0018 0.0083 0.009
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0033 0.0037
Echinococcus granulosus leukotriene A 4 hydrolase 0.0013 0.003 0.0031
Trichomonas vaginalis protein kinase inhibitor, putative 0.0064 0.0563 0.2181
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0036 0.0014
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0802 0.0894
Brugia malayi G protein-coupled receptor 0.0016 0.006 0.0067

Activities

Activity type Activity value Assay description Source Reference
CLfree (ADMET) = 1.7 l hr-1 kg-1 Pharmacokinectic property of the compound was measured in rat ChEMBL. 12873508
LD50 (ADMET) < 25 mg kg-1 In vivo toxixcity of the compound was determined in mice i.v. ChEMBL. 12873508
MIC (functional) = 0.125 ug ml-1 Compound was evaluated in PAM 1032 strain of Pseudomonas aeruginosa for its effect on levofloxacin (20 ug/mL) potentiation ChEMBL. 11266165
MIC (functional) = 0.125 ug ml-1 Compound was evaluated in PAM 1032 strain of Pseudomonas aeruginosa for its effect on levofloxacin (40 ug/mL) potentiation ChEMBL. 11266165
MIC (functional) = 2 ug ml-1 Compound was evaluated in PAM 1032 strain of Pseudomonas aeruginosa for its effect on levofloxacin ( 10 ug/mL) potentiation ChEMBL. 11266165
MIC (functional) = 4 ug ml-1 Compound was evaluated in PAM 1032 strain of Pseudomonas aeruginosa for its effect on levofloxacin (microg/mL) potentiation ChEMBL. 11266165
MIC (functional) = 4 ug ml-1 Compound was evaluated in PAM 1032 strain of Pseudomonas aeruginosa for its effect on levofloxacin ( 5 ug/mL) potentiation ChEMBL. 11266165
MIC (functional) > 512 ug ml-1 In vitro minimum concentration of the efflux pump inhibitor required to inhibit the growth of PAM 1723 a strain of Pseudomonas aeruginosa ChEMBL. 12873508
MIC (functional) > 512 ug ml-1 Tested for the minimum inhibitory concentration (MIC) against growth of PAM 1032 , a strain of Pseudomonas aeruginosa ChEMBL. 11858997
MLD (ADMET) < 25 mg kg-1 In vivo minimum lethal dose causing lethality to >/=66% of the mice tested i.v. ChEMBL. 12873508
MLD (ADMET) = 200 mg kg-1 In vivo minimum lethal dose causing lethality to >/=66% of the mice tested i.p. ChEMBL. 12873508
MPC (functional) = 10 ug ml-1 In vitro minimum concentration of the efflux pump inhibitor required to reduce (potentiate) the MIC of fuoroquinolone levofloxacin 8-fold (LVFX) ChEMBL. 12873508
MPC (functional) = 20 ug ml-1 Minimum concentration of compound required to reduce the MIC of levofloxacin 8-fold in PAM 1032 strain of Pseudomonas aeruginosa that over expresses MexAB-OprM efflux pump ChEMBL. 11266165
MPC8 (functional) = 10 ug ml-1 Minimum concentration of the compound required to reduce (potentiate) the MIC of levofloxacin of Pseudomonas aeruginosa by 8-folds ChEMBL. 11858997

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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