Detailed information for compound 1556430

Basic information

Technical information
  • TDR Targets ID: 1556430
  • Name: dimethyl 1-(3-chlorophenyl)triazole-4,5-dicar boxylate
  • MW: 295.679 | Formula: C12H10ClN3O4
  • H donors: 0 H acceptors: 4 LogP: 2.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1c(nnn1c1cccc(c1)Cl)C(=O)OC
  • InChi: 1S/C12H10ClN3O4/c1-19-11(17)9-10(12(18)20-2)16(15-14-9)8-5-3-4-7(13)6-8/h3-6H,1-2H3
  • InChiKey: JCVAGQBHXATDSO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(3-chlorophenyl)triazole-4,5-dicarboxylic acid dimethyl ester
  • dimethyl 1-(3-chlorophenyl)-1,2,3-triazole-4,5-dicarboxylate
  • MLS000859847
  • SMR000460826
  • dimethyl 1-(3-chlorophenyl)-1H-1,2,3-triazole-4,5-dicarboxylate
  • SEW 00279
  • ZINC00105840

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0041 0.0188 0.017
Echinococcus multilocularis beta adrenergic receptor kinase 0.1878 1 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0041 0.0188 0.7785
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0151 0.0133
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0041 0.0188 0.0686
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0046 0.0216 1
Echinococcus granulosus oxysterol binding protein 3 0.0041 0.0188 0.017
Onchocerca volvulus 0.0034 0.0151 0.0084
Entamoeba histolytica protein kinase, putative 0.0046 0.0216 0.1213
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0041 0.0188 0.7785
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.009 0.0062
Schistosoma mansoni axis inhibition protein axin 0.0217 0.1127 0.1127
Echinococcus multilocularis pleckstrin y domain containing family A 0.0041 0.0188 0.017
Echinococcus granulosus calcium dependent secretion activator 1 0.0041 0.0188 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Onchocerca volvulus 0.0041 0.0188 0.0379
Schistosoma mansoni myotubularin-related protein 0.0041 0.0188 0.0188
Echinococcus multilocularis Rho GTPase activating protein 24 0.0041 0.0188 0.017
Onchocerca volvulus 0.0041 0.0188 0.0379
Entamoeba histolytica hypothetical protein 0.0041 0.0188 0.0944
Echinococcus multilocularis Pleckstrin y 0.0041 0.0188 0.017
Echinococcus granulosus Pleckstrin y 0.0041 0.0188 0.017
Schistosoma mansoni hypothetical protein 0.0018 0.0063 0.0063
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Schistosoma mansoni oxysterol-binding protein 1 0.0041 0.0188 0.0188
Echinococcus granulosus Pleckstrin y 0.0041 0.0188 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Entamoeba histolytica protein kinase, putative 0.0046 0.0216 0.1213
Brugia malayi A-kinase anchor protein 10, precursor 0.0217 0.1127 0.471
Loa Loa (eye worm) hypothetical protein 0.0038 0.0173 0.0145
Echinococcus granulosus cpg binding protein 0.0034 0.015 0.0133
Schistosoma mansoni regulator of G protein signaling 0.0217 0.1127 0.1127
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Leishmania major hypothetical protein, conserved 0.0041 0.0188 0.7785
Echinococcus granulosus myotubularin protein 13 0.0041 0.0188 0.017
Schistosoma mansoni goodpasture antigen-binding protein 0.0041 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0217 0.1127 0.1101
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0188 0.7785
Schistosoma mansoni zinc finger protein 0.0041 0.0188 0.0188
Echinococcus multilocularis Pleckstrin y 0.0041 0.0188 0.017
Onchocerca volvulus outspread protein homolog 0.0041 0.0188 0.0379
Toxoplasma gondii Oxysterol-binding protein 0.0041 0.0188 0.4641
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Echinococcus multilocularis GPCR, family 2 0.0018 0.0063 0.0045
Schistosoma mansoni cpg binding protein 0.0032 0.0141 0.0141
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0151 0.0133
Trypanosoma cruzi PH domain containing protein, putative 0.0041 0.0188 0.7785
Echinococcus multilocularis pdz domain containing protein 0.0041 0.0188 0.017
Onchocerca volvulus 0.0266 0.139 1
Plasmodium falciparum oxysterol-binding protein, putative 0.0041 0.0188 0.7785
Entamoeba histolytica protein kinase, putative 0.0046 0.0216 0.1213
Schistosoma mansoni hypothetical protein 0.0018 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Entamoeba histolytica hypothetical protein 0.0046 0.0216 0.1213
Entamoeba histolytica hypothetical protein 0.0217 0.1127 1
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0041 0.0188 0.7785
Trypanosoma brucei rac serine-threonine kinase, putative 0.0046 0.0216 1
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0046 0.0216 1
Brugia malayi Oxysterol-binding protein 0.0041 0.0188 0.0686
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0046 0.0216 1
Echinococcus multilocularis dynamin 1 0.0041 0.0188 0.017
Echinococcus granulosus DCC interacting protein 13 beta 0.0041 0.0188 0.017
Entamoeba histolytica ARF GTPase activating protein, putative 0.0041 0.0188 0.0944
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0041 0.0188 0.017
Trichomonas vaginalis centaurin gamma, putative 0.0041 0.0188 0.1304
Onchocerca volvulus 0.0041 0.0188 0.0379
Schistosoma mansoni cpg binding protein 0.0034 0.015 0.015
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Trypanosoma cruzi NIMA-related kinase, putative 0.0046 0.0216 1
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0041 0.0188 0.017
Echinococcus granulosus cytohesin 1 0.0041 0.0188 0.017
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0046 0.0216 1
Entamoeba histolytica hypothetical protein 0.0041 0.0188 0.0944
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0041 0.0188 0.0686
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0041 0.0188 0.0944
Schistosoma mansoni hypothetical protein 0.0038 0.0173 0.0173
Brugia malayi Muscleblind-like protein 0.0158 0.0811 0.3355
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0041 0.0188 0.1304
Echinococcus multilocularis Regulator of G protein signaling 20 0.0217 0.1127 0.1111
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0041 0.0188 0.0944
Entamoeba histolytica protein kinase, putative 0.0046 0.0216 0.1213
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0041 0.0188 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Loa Loa (eye worm) RGS-3 protein 0.0217 0.1127 0.1101
Echinococcus granulosus pdz domain containing protein 0.0041 0.0188 0.017
Loa Loa (eye worm) hypothetical protein 0.0056 0.0267 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.2361 0.2361
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.009 0.5
Entamoeba histolytica PH domain containing protein 0.0041 0.0188 0.0944
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0216 0.1213
Schistosoma mansoni regulator of G protein signaling 0.0217 0.1127 0.1127
Loa Loa (eye worm) hypothetical protein 0.0217 0.1127 0.1101
Schistosoma mansoni hypothetical protein 0.0041 0.0188 0.0188
Schistosoma mansoni oxysterol-binding protein 1 0.0041 0.0188 0.0188
Entamoeba histolytica hypothetical protein 0.0041 0.0188 0.0944
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0217 0.1127 0.1111
Trypanosoma cruzi hypothetical protein 0.0041 0.0188 0.7785
Entamoeba histolytica hypothetical protein 0.0041 0.0188 0.0944
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0041 0.0188 0.016
Schistosoma mansoni ap endonuclease 0.0023 0.009 0.009
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0041 0.0188 0.0944
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0216 0.1213
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Schistosoma mansoni serine/threonine protein kinase 0.1878 1 1
Schistosoma mansoni serine/threonine-protein kinase 0.0046 0.0216 0.0216
Plasmodium vivax SET domain protein, putative 0.0034 0.0151 0.4859
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.009 0.5
Echinococcus granulosus G protein coupled receptor kinase 1 0.1661 0.8842 0.884
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0041 0.0188 0.7785
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0151 0.0151
Echinococcus multilocularis Pleckstrin y 0.0041 0.0188 0.017
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Schistosoma mansoni goodpasture antigen-binding protein 0.0041 0.0188 0.0188
Trichomonas vaginalis centaurin beta, putative 0.0041 0.0188 0.1304
Schistosoma mansoni z-protein (S1r protein) 0.0217 0.1127 0.1127
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Echinococcus multilocularis regulator of G protein signaling 7 0.0217 0.1127 0.1111
Loa Loa (eye worm) hypothetical protein 0.0217 0.1127 0.1101
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0063 0.0045
Trypanosoma cruzi hypothetical protein 0.0041 0.0188 0.7785
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0231 0.1203 0.1178
Schistosoma mansoni hypothetical protein 0.0041 0.0188 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.1218 0.1193
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.009 0.0072
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0216 0.1213
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Toxoplasma gondii AtPH1 family protein 0.0041 0.0188 0.4641
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0046 0.0216 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Loa Loa (eye worm) PH domain-containing protein 0.0041 0.0188 0.016
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.009 0.0596
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Brugia malayi Regulator of G protein signaling domain containing protein 0.0217 0.1127 0.471
Entamoeba histolytica protein kinase, putative 0.0046 0.0216 0.1213
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0041 0.0188 0.017
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.034 0.034
Echinococcus granulosus GPCR family 2 0.0018 0.0063 0.0045
Schistosoma mansoni vav2 0.0041 0.0188 0.0188
Schistosoma mansoni ap endonuclease 0.0023 0.009 0.009
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0046 0.0216 1
Trypanosoma cruzi NIMA-related kinase, putative 0.0046 0.0216 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0141 0.0123
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0046 0.0216 1
Brugia malayi Dynamin 0.0041 0.0188 0.0686
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Loa Loa (eye worm) PXA domain-containing protein 0.0217 0.1127 0.1101
Echinococcus multilocularis Ras associated and pleckstrin y 0.0041 0.0188 0.017
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0217 0.1127 0.1127
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0041 0.0188 0.7785
Echinococcus multilocularis DCC interacting protein 13 beta 0.0041 0.0188 0.017
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Trichomonas vaginalis kinesin light chain, putative 0.0041 0.0188 0.1304
Echinococcus multilocularis axis inhibition protein axin 0.0217 0.1127 0.1111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0063 0.0035
Onchocerca volvulus 0.0041 0.0188 0.0379
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0046 0.0216 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0301 1
Trypanosoma cruzi hypothetical protein 0.0041 0.0188 0.7785
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Trypanosoma cruzi hypothetical protein 0.0041 0.0188 0.7785
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0063 0.0045
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0041 0.0188 0.0379
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Entamoeba histolytica protein kinase, putative 0.0046 0.0216 0.1213
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0046 0.0216 1
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0041 0.0188 0.0188
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.009 0.5
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0151 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Brugia malayi hypothetical protein 0.0041 0.0188 0.0686
Schistosoma mansoni rho gtpase activating protein 0.0041 0.0188 0.0188
Onchocerca volvulus 0.0041 0.0188 0.0379
Echinococcus granulosus oxysterol binding protein 1 0.0041 0.0188 0.017
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Echinococcus multilocularis axis inhibition protein axin 0.0217 0.1127 0.1111
Trichomonas vaginalis centaurin alpha, putative 0.0041 0.0188 0.1304
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0041 0.0188 0.7785
Echinococcus multilocularis regulator of G protein signaling 0.0217 0.1127 0.1111
Brugia malayi Cytohesin 3 0.0041 0.0188 0.0686
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Brugia malayi Pleckstrin Homology Domain 0.0041 0.0188 0.0686
Entamoeba histolytica hypothetical protein, conserved 0.0041 0.0188 0.0944
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0041 0.0188 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Brugia malayi Pre-SET motif family protein 0.0034 0.0151 0.0529
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0267 0.0239
Trypanosoma brucei PH domain containing protein, putative 0.0041 0.0188 0.7785
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.1127 0.8094
Echinococcus multilocularis regulator of G protein signaling 3 0.0217 0.1127 0.1111
Echinococcus granulosus regulator of G protein signaling 7 0.0217 0.1127 0.1111
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0041 0.0188 0.1304
Schistosoma mansoni hypothetical protein 0.0041 0.0188 0.0188
Entamoeba histolytica hypothetical protein 0.0041 0.0188 0.0944
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0041 0.0188 0.0944
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0063 0.0045
Brugia malayi regulator of G-protein signaling rgs-7 0.0217 0.1127 0.471
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0041 0.0188 0.0379
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0231 0.1203 0.5037
Trypanosoma cruzi hypothetical protein 0.0041 0.0188 0.7785
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Entamoeba histolytica protein kinase, putative 0.0046 0.0216 0.1213
Leishmania major serine/threonine-protein kinase a, putative 0.0046 0.0216 1
Brugia malayi Cadps2 protein 0.0041 0.0188 0.0686
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0029 0.001
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0041 0.0188 0.1304
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Echinococcus granulosus Pleckstrin y 0.0041 0.0188 0.017
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Trypanosoma brucei protein kinase, putative 0.0046 0.0216 1
Schistosoma mansoni hypothetical protein 0.0458 0.2416 0.2416
Schistosoma mansoni growth factor receptor-bound protein 0.0041 0.0188 0.0188
Trypanosoma cruzi PH domain containing protein, putative 0.0041 0.0188 0.7785
Schistosoma mansoni dynamin 0.0041 0.0188 0.0188
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0046 0.0216 1
Toxoplasma gondii phosphatidylinositol transfer protein 0.0041 0.0188 0.4641
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Loa Loa (eye worm) hypothetical protein 0.0217 0.1127 0.1101
Brugia malayi probable spectrin beta chain 0.0041 0.0188 0.0686
Leishmania major protein kinase, putative 0.0046 0.0216 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Trichomonas vaginalis protein transport protein sec7, putative 0.0041 0.0188 0.1304
Trypanosoma cruzi PH domain containing protein, putative 0.0041 0.0188 0.7785
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0041 0.0188 0.017
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0448 0.2361 0.2339
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0041 0.0188 0.017
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0041 0.0188 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0217 0.1127 0.1111
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0041 0.0188 0.017
Entamoeba histolytica hypothetical protein 0.0217 0.1127 1
Trypanosoma cruzi Protein kinase B 0.0046 0.0216 1
Echinococcus multilocularis Oxysterol binding protein 11 0.0041 0.0188 0.017
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0046 0.0216 1
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Echinococcus granulosus Regulator of G protein signaling 20 0.0217 0.1127 0.1111
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Onchocerca volvulus Putative zinc finger protein 0.0041 0.0188 0.0379
Echinococcus granulosus dnaJ subfamily B 0.0458 0.2416 0.2403
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0173 0.0621
Brugia malayi regulator of G-protein signaling egl-10 0.0217 0.1127 0.471
Leishmania major folate/biopterin transporter, putative 0.0046 0.0216 1
Brugia malayi Dynamin 0.0041 0.0188 0.0686
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.009 0.0596
Plasmodium falciparum PH domain-containing protein, putative 0.0041 0.0188 0.7785
Echinococcus granulosus serine/threonine protein kinase 0.0046 0.0216 0.0198
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0041 0.0188 0.016
Echinococcus granulosus regulator of G protein signaling 3 0.0217 0.1127 0.1111
Leishmania major hypothetical protein, conserved 0.0041 0.0188 0.7785
Trypanosoma cruzi hypothetical protein 0.0041 0.0188 0.7785
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.009 0.5
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.009 0.5
Schistosoma mansoni zinc finger protein 0.0041 0.0188 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Schistosoma mansoni axis inhibition protein axin 0.0217 0.1127 0.1127
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0029 0.001
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0041 0.0188 0.017
Echinococcus multilocularis G protein coupled receptor kinase 1 0.1661 0.8842 0.884
Brugia malayi MAX-1A 0.0041 0.0188 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.1127 0.8094
Schistosoma mansoni hypothetical protein 0.0041 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0041 0.0188 0.1304
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0046 0.0216 0.5962
Echinococcus granulosus oxysterol binding protein 9 0.0041 0.0188 0.017
Echinococcus multilocularis cpg binding protein 0.0034 0.015 0.0133
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0041 0.0188 0.017
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Onchocerca volvulus 0.0041 0.0188 0.0379
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0231 0.1203 0.1187
Brugia malayi PXA domain containing protein 0.0217 0.1127 0.471
Echinococcus multilocularis GRB2 associated binding protein 3 0.0041 0.0188 0.017
Echinococcus granulosus muscleblind protein 0.0158 0.0811 0.0794
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0041 0.0188 0.017
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0217 0.1127 0.1127
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0041 0.0188 0.0944
Loa Loa (eye worm) AGC/AKT protein kinase 0.0046 0.0216 0.0188
Schistosoma mansoni hypothetical protein 0.0018 0.0063 0.0063
Entamoeba histolytica PH domain containing protein 0.0041 0.0188 0.0944
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0046 0.0216 0.1505
Trypanosoma cruzi PH domain containing protein, putative 0.0041 0.0188 0.7785
Echinococcus multilocularis actin binding protein anillin 0.0041 0.0188 0.017
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Echinococcus granulosus regulator of G protein signaling 3 0.0217 0.1127 0.1111
Loa Loa (eye worm) oxysterol binding protein 0.0041 0.0188 0.016
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Schistosoma mansoni hypothetical protein 0.0041 0.0188 0.0188
Toxoplasma gondii hypothetical protein 0.0041 0.0188 0.4641
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0216 0.1213
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0041 0.0188 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Schistosoma mansoni hypothetical protein 0.0018 0.0063 0.0063
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0041 0.0188 0.7785
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.1127 0.8094
Loa Loa (eye worm) uncoordinated protein 104 0.0041 0.0188 0.016
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.009 0.0072
Echinococcus granulosus Rho GTPase activating protein 24 0.0041 0.0188 0.017
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0041 0.0188 0.017
Schistosoma mansoni regulator of G protein signaling 0.0217 0.1127 0.1127
Trichomonas vaginalis protein transport protein sec7, putative 0.0041 0.0188 0.1304
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0267 0.1026
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0448 0.2361 1
Plasmodium falciparum calcium-dependent protein kinase 7 0.0046 0.0216 1
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0063 0.0151
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Loa Loa (eye worm) hypothetical protein 0.0158 0.0811 0.0784
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0231 0.1203 0.1178
Brugia malayi Regulator of G protein signaling domain containing protein 0.0217 0.1127 0.471
Brugia malayi Variant SH3 domain containing protein 0.0041 0.0188 0.0686
Brugia malayi hypothetical protein 0.0217 0.1127 0.471
Trichomonas vaginalis hypothetical protein 0.0041 0.0188 0.1304
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0041 0.0188 0.017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0141 0.0112
Echinococcus multilocularis dnaJ subfamily B 0.0458 0.2416 0.2403
Brugia malayi CXXC zinc finger family protein 0.0032 0.0141 0.0484
Loa Loa (eye worm) hypothetical protein 0.0217 0.1127 0.1101
Schistosoma mansoni regulator of G protein signaling 0.0217 0.1127 0.1127
Leishmania major protein kinase, putative 0.0046 0.0216 1
Loa Loa (eye worm) cytohesin 3 0.0041 0.0188 0.016
Echinococcus multilocularis oxysterol binding protein 3 0.0041 0.0188 0.017
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Echinococcus multilocularis muscleblind protein 1 0.0158 0.0811 0.0794
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0046 0.0216 0.1505
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0041 0.0188 0.017
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0046 0.0216 1
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Entamoeba histolytica hypothetical protein 0.0046 0.0216 0.1213
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.1127 0.8094
Echinococcus granulosus beta 1 syntrophin 0.0041 0.0188 0.017
Brugia malayi Protein kinase domain containing protein 0.0046 0.0216 0.0806
Brugia malayi Pre-SET motif family protein 0.0234 0.1218 0.5102
Loa Loa (eye worm) Plekhf2 protein 0.0041 0.0188 0.016
Brugia malayi TBC domain containing protein 0.0041 0.0188 0.0686
Trichomonas vaginalis alpha chimerin, putative 0.0041 0.0188 0.1304
Echinococcus multilocularis rac serine:threonine kinase 0.0046 0.0216 0.0198
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0063 0.0151
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0151 0.0151
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Entamoeba histolytica PH domain containing protein 0.0041 0.0188 0.0944
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0046 0.0216 1
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0046 0.0216 1
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0046 0.0216 1
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0041 0.0188 0.0944
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0041 0.0188 0.017
Toxoplasma gondii hypothetical protein 0.0041 0.0188 0.4641
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Echinococcus multilocularis oxysterol binding protein 1 0.0041 0.0188 0.017
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0151 0.0133
Onchocerca volvulus Protein melted homolog 0.0041 0.0188 0.0379
Entamoeba histolytica hypothetical protein 0.0217 0.1127 1
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.1878 1 1
Loa Loa (eye worm) hypothetical protein 0.0158 0.0811 0.0784
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0041 0.0188 0.7785
Schistosoma mansoni centaurin alpha 0.0041 0.0188 0.0188
Brugia malayi Plekhf2 protein 0.0041 0.0188 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.1878 1 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0217 0.1127 0.1111
Schistosoma mansoni cpg binding protein 0.0034 0.015 0.015
Echinococcus multilocularis muscleblind protein 0.0158 0.0811 0.0794
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0041 0.0188 0.7785
Brugia malayi PXA domain containing protein 0.0217 0.1127 0.471
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0041 0.0188 0.0686
Brugia malayi PH domain containing protein 0.0041 0.0188 0.0686
Onchocerca volvulus 0.0041 0.0188 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0151 0.2897
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Toxoplasma gondii protein kinase domain-containing protein 0.0046 0.0216 0.5962
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0046 0.0216 1
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0231 0.1203 0.1187
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.1127 0.8094
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Plasmodium vivax PH domain containing protein 0.0041 0.0188 0.7785
Echinococcus granulosus axis inhibition protein axin 0.0217 0.1127 0.1111
Trichomonas vaginalis centaurin/arf, putative 0.0041 0.0188 0.1304
Echinococcus multilocularis regulator of G protein signaling 7 0.0217 0.1127 0.1111
Schistosoma mansoni regulator of G protein signaling 0.0217 0.1127 0.1127
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Loa Loa (eye worm) hypothetical protein 0.0217 0.1127 0.1101
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0217 0.1127 0.1127
Echinococcus multilocularis myotubularin protein 13 0.0041 0.0188 0.017
Echinococcus granulosus axis inhibition protein axin 0.0217 0.1127 0.1111
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0267 0.1026
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0041 0.0188 0.1304
Trypanosoma cruzi hypothetical protein 0.0041 0.0188 0.7785
Schistosoma mansoni syntrophin 0.0041 0.0188 0.0188
Brugia malayi hypothetical protein 0.0217 0.1127 0.471
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0041 0.0188 0.016
Brugia malayi Uncoordinated protein 104 0.0041 0.0188 0.0686
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0063 0.0035
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0217 0.1127 0.8094
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0041 0.0188 0.1304
Schistosoma mansoni dynamin 0.0041 0.0188 0.0188
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0041 0.0188 0.0188
Echinococcus granulosus regulator of G protein signaling 7 0.0217 0.1127 0.1111
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Echinococcus granulosus Oxysterol binding protein 11 0.0041 0.0188 0.017
Echinococcus multilocularis calcium dependent secretion activator 1 0.0041 0.0188 0.017
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0041 0.0188 0.016
Echinococcus granulosus dynamin 1 0.0041 0.0188 0.017
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Trichomonas vaginalis centaurin/arf, putative 0.0041 0.0188 0.1304
Brugia malayi Syntrophin-1 0.0041 0.0188 0.0686
Loa Loa (eye worm) hypothetical protein 0.0034 0.0151 0.0123
Echinococcus multilocularis expressed protein 0.0217 0.1127 0.1111
Trichomonas vaginalis set domain proteins, putative 0.0266 0.139 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0217 0.1127 0.1101
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.1127 0.8094
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0018 0.0018
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.009 0.0267
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Echinococcus granulosus GRB2 associated binding protein 3 0.0041 0.0188 0.017
Echinococcus granulosus expressed protein 0.0217 0.1127 0.1111
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0041 0.0188 0.0944
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0188 0.1304
Echinococcus multilocularis cytohesin 1 0.0041 0.0188 0.017
Brugia malayi Variant SH3 domain containing protein 0.0041 0.0188 0.0686
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0216 0.1505
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0216 0.1213
Echinococcus multilocularis beta 1 syntrophin 0.0041 0.0188 0.017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0151 0.0151
Loa Loa (eye worm) syntrophin-1 0.0041 0.0188 0.016
Loa Loa (eye worm) rho-GTPase-activating 0.0041 0.0188 0.016
Loa Loa (eye worm) hypothetical protein 0.0041 0.0188 0.016
Echinococcus multilocularis oxysterol binding protein 9 0.0041 0.0188 0.017
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0063 0.0045
Echinococcus granulosus pleckstrin y domain containing family A 0.0041 0.0188 0.017
Entamoeba histolytica p21-activated kinase 0.0046 0.0216 0.1213
Schistosoma mansoni serine/threonine-protein kinase 0.0046 0.0216 0.0216
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0216 0.1213
Brugia malayi Oxysterol binding protein 0.0041 0.0188 0.0686

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.5481 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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